0s autopkgtest [23:16:40]: starting date and time: 2026-02-09 23:16:40+0000 0s autopkgtest [23:16:40]: git checkout: 508d4a25 a-v-ssh wait_for_ssh: demote "ssh connection failed" to a debug message 0s autopkgtest [23:16:40]: host juju-7f2275-prod-proposed-migration-environment-9; command line: /home/ubuntu/autopkgtest/runner/autopkgtest --output-dir /tmp/autopkgtest-work.1m9vjj51/out --timeout-copy=6000 --setup-commands 'ln -s /dev/null /etc/systemd/system/bluetooth.service; printf "http_proxy=http://squid.internal:3128\nhttps_proxy=http://squid.internal:3128\nno_proxy=127.0.0.1,127.0.1.1,localhost,localdomain,internal,login.ubuntu.com,archive.ubuntu.com,ports.ubuntu.com,security.ubuntu.com,ddebs.ubuntu.com,changelogs.ubuntu.com,keyserver.ubuntu.com,launchpadlibrarian.net,launchpadcontent.net,launchpad.net,keystone.ps5.canonical.com,objectstorage.prodstack5.canonical.com,radosgw.ps5.canonical.com\n" >> /etc/environment' --apt-pocket=proposed=src:r-cran-ggplot2 --apt-upgrade r-cran-dosefinding --timeout-short=300 --timeout-copy=20000 --timeout-build=20000 --env=ADT_TEST_TRIGGERS=r-cran-ggplot2/4.0.2+dfsg-1 -- lxd -r lxd-armhf-10.145.243.107 lxd-armhf-10.145.243.107:autopkgtest/ubuntu/resolute/armhf 26s autopkgtest [23:17:06]: testbed dpkg architecture: armhf 28s autopkgtest [23:17:08]: testbed apt version: 3.1.15 32s autopkgtest [23:17:12]: @@@@@@@@@@@@@@@@@@@@ test bed setup 34s autopkgtest [23:17:14]: testbed release detected to be: None 42s autopkgtest [23:17:22]: updating testbed package index (apt update) 45s Get:1 http://ftpmaster.internal/ubuntu resolute-proposed InRelease [124 kB] 45s Get:2 http://ftpmaster.internal/ubuntu resolute InRelease [124 kB] 45s Get:3 http://ftpmaster.internal/ubuntu resolute-updates InRelease [124 kB] 45s Get:4 http://ftpmaster.internal/ubuntu resolute-security InRelease [124 kB] 46s Get:5 http://ftpmaster.internal/ubuntu resolute-proposed/universe Sources [1645 kB] 48s Get:6 http://ftpmaster.internal/ubuntu resolute-proposed/main Sources [176 kB] 48s Get:7 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse Sources [29.4 kB] 48s Get:8 http://ftpmaster.internal/ubuntu resolute-proposed/main armhf Packages [246 kB] 48s Get:9 http://ftpmaster.internal/ubuntu resolute-proposed/universe armhf Packages [1405 kB] 50s Get:10 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse armhf Packages [7452 B] 51s Get:11 http://ftpmaster.internal/ubuntu resolute/restricted Sources [15.1 kB] 51s Get:12 http://ftpmaster.internal/ubuntu resolute/main Sources [1398 kB] 53s Get:13 http://ftpmaster.internal/ubuntu resolute/universe Sources [21.4 MB] 87s Get:14 http://ftpmaster.internal/ubuntu resolute/main armhf Packages [1374 kB] 89s Get:15 http://ftpmaster.internal/ubuntu resolute/universe armhf Packages [15.3 MB] 114s Fetched 43.5 MB in 1min 10s (625 kB/s) 115s Reading package lists... 121s autopkgtest [23:18:41]: upgrading testbed (apt dist-upgrade and autopurge) 122s Reading package lists... 123s Building dependency tree... 123s Reading state information... 123s Calculating upgrade... 124s The following packages will be upgraded: 124s cryptsetup-bin dracut-install iproute2 iptables libcryptsetup12 libip4tc2 124s libip6tc2 libxtables12 wget 124s 9 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 124s Need to get 2407 kB of archives. 124s After this operation, 152 kB of additional disk space will be used. 124s Get:1 http://ftpmaster.internal/ubuntu resolute/main armhf iptables armhf 1.8.11-2ubuntu3 [345 kB] 125s Get:2 http://ftpmaster.internal/ubuntu resolute/main armhf libip4tc2 armhf 1.8.11-2ubuntu3 [22.0 kB] 125s Get:3 http://ftpmaster.internal/ubuntu resolute/main armhf libip6tc2 armhf 1.8.11-2ubuntu3 [22.3 kB] 125s Get:4 http://ftpmaster.internal/ubuntu resolute/main armhf libxtables12 armhf 1.8.11-2ubuntu3 [33.5 kB] 125s Get:5 http://ftpmaster.internal/ubuntu resolute/main armhf iproute2 armhf 6.18.0-1ubuntu1 [1123 kB] 128s Get:6 http://ftpmaster.internal/ubuntu resolute/main armhf libcryptsetup12 armhf 2:2.8.0-1ubuntu3 [254 kB] 129s Get:7 http://ftpmaster.internal/ubuntu resolute/main armhf wget armhf 1.25.0-2ubuntu4 [327 kB] 129s Get:8 http://ftpmaster.internal/ubuntu resolute/main armhf cryptsetup-bin armhf 2:2.8.0-1ubuntu3 [232 kB] 130s Get:9 http://ftpmaster.internal/ubuntu resolute/main armhf dracut-install armhf 109-11ubuntu1 [47.9 kB] 130s Preconfiguring packages ... 130s Fetched 2407 kB in 6s (418 kB/s) 130s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 68683 files and directories currently installed.) 130s Preparing to unpack .../0-iptables_1.8.11-2ubuntu3_armhf.deb ... 130s Unpacking iptables (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 130s Preparing to unpack .../1-libip4tc2_1.8.11-2ubuntu3_armhf.deb ... 130s Unpacking libip4tc2:armhf (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 130s Preparing to unpack .../2-libip6tc2_1.8.11-2ubuntu3_armhf.deb ... 130s Unpacking libip6tc2:armhf (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 130s Preparing to unpack .../3-libxtables12_1.8.11-2ubuntu3_armhf.deb ... 130s Unpacking libxtables12:armhf (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 131s Preparing to unpack .../4-iproute2_6.18.0-1ubuntu1_armhf.deb ... 131s Unpacking iproute2 (6.18.0-1ubuntu1) over (6.16.0-1ubuntu3) ... 131s Preparing to unpack .../5-libcryptsetup12_2%3a2.8.0-1ubuntu3_armhf.deb ... 131s Unpacking libcryptsetup12:armhf (2:2.8.0-1ubuntu3) over (2:2.8.0-1ubuntu2) ... 131s Preparing to unpack .../6-wget_1.25.0-2ubuntu4_armhf.deb ... 131s Unpacking wget (1.25.0-2ubuntu4) over (1.25.0-2ubuntu3) ... 131s Preparing to unpack .../7-cryptsetup-bin_2%3a2.8.0-1ubuntu3_armhf.deb ... 131s Unpacking cryptsetup-bin (2:2.8.0-1ubuntu3) over (2:2.8.0-1ubuntu2) ... 131s Preparing to unpack .../8-dracut-install_109-11ubuntu1_armhf.deb ... 131s Unpacking dracut-install (109-11ubuntu1) over (109-9ubuntu1) ... 131s Setting up libip4tc2:armhf (1.8.11-2ubuntu3) ... 131s Setting up wget (1.25.0-2ubuntu4) ... 131s Setting up libip6tc2:armhf (1.8.11-2ubuntu3) ... 131s Setting up libxtables12:armhf (1.8.11-2ubuntu3) ... 131s Setting up dracut-install (109-11ubuntu1) ... 131s Setting up libcryptsetup12:armhf (2:2.8.0-1ubuntu3) ... 131s Setting up cryptsetup-bin (2:2.8.0-1ubuntu3) ... 131s Setting up iptables (1.8.11-2ubuntu3) ... 131s Setting up iproute2 (6.18.0-1ubuntu1) ... 131s Processing triggers for man-db (2.13.1-1build1) ... 132s Processing triggers for install-info (7.2-5) ... 133s Processing triggers for libc-bin (2.42-2ubuntu4) ... 135s Reading package lists... 135s Building dependency tree... 135s Reading state information... 135s Solving dependencies... 136s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 139s autopkgtest [23:18:59]: rebooting testbed after setup commands that affected boot 187s autopkgtest [23:19:47]: testbed running kernel: Linux 6.8.0-87-generic #88~22.04.1-Ubuntu SMP PREEMPT_DYNAMIC Tue Oct 14 14:00:09 UTC 2 220s autopkgtest [23:20:20]: @@@@@@@@@@@@@@@@@@@@ apt-source r-cran-dosefinding 235s Get:1 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (dsc) [2322 B] 235s Get:2 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (tar) [698 kB] 235s Get:3 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (diff) [4244 B] 235s gpgv: Signature made Fri Mar 14 00:07:33 2025 UTC 235s gpgv: using RSA key 73471499CC60ED9EEE805946C5BD6C8F2295D502 235s gpgv: issuer "plessy@debian.org" 235s gpgv: Can't check signature: No public key 235s dpkg-source: warning: cannot verify inline signature for ./r-cran-dosefinding_1.3-1-1.dsc: no acceptable signature found 235s autopkgtest [23:20:35]: testing package r-cran-dosefinding version 1.3-1-1 237s autopkgtest [23:20:37]: build not needed 241s autopkgtest [23:20:41]: test run-unit-test: preparing testbed 243s Reading package lists... 243s Building dependency tree... 243s Reading state information... 243s Solving dependencies... 244s The following NEW packages will be installed: 244s fontconfig fontconfig-config fonts-dejavu-core fonts-dejavu-mono 244s fonts-font-awesome fonts-glyphicons-halflings fonts-mathjax 244s javascript-common libblas3 libcairo2 libdatrie1 libdeflate0 libfontconfig1 244s libfreetype6 libgfortran5 libgomp1 libgraphite2-3 libharfbuzz0b libice6 244s libjbig0 libjpeg-turbo8 libjpeg8 libjs-bootstrap libjs-bootstrap4 libjs-d3 244s libjs-es5-shim libjs-highlight.js libjs-jquery libjs-jquery-datatables 244s libjs-jquery-selectize.js libjs-jquery-ui libjs-json libjs-mathjax 244s libjs-microplugin.js libjs-modernizr libjs-popper.js libjs-prettify 244s libjs-sifter.js libjs-twitter-bootstrap-datepicker liblapack3 liblerc4 244s liblua5.4-0 libpango-1.0-0 libpangocairo-1.0-0 libpangoft2-1.0-0 244s libpaper-utils libpaper2 libpixman-1-0 libsharpyuv0 libsm6 libtcl8.6 244s libthai-data libthai0 libtiff6 libtk8.6 libwebp7 libxcb-render0 libxcb-shm0 244s libxft2 libxrender1 libxss1 libxt6t64 node-bootstrap-sass node-html5shiv 244s node-normalize.css pandoc pandoc-data r-base-core r-cran-base64enc 244s r-cran-brio r-cran-bslib r-cran-cachem r-cran-callr r-cran-cli 244s r-cran-codetools r-cran-commonmark r-cran-crayon r-cran-desc r-cran-diffobj 244s r-cran-digest r-cran-dosefinding r-cran-evaluate r-cran-farver 244s r-cran-fastmap r-cran-fontawesome r-cran-fs r-cran-ggplot2 r-cran-glue 244s r-cran-gtable r-cran-highr r-cran-htmltools r-cran-httpuv r-cran-isoband 244s r-cran-jquerylib r-cran-jsonlite r-cran-knitr r-cran-labeling r-cran-later 244s r-cran-lattice r-cran-lifecycle r-cran-littler r-cran-magrittr r-cran-mass 244s r-cran-matrix r-cran-memoise r-cran-mime r-cran-multcomp r-cran-mvtnorm 244s r-cran-nlme r-cran-numderiv r-cran-pkgbuild r-cran-pkgkitten r-cran-pkgload 244s r-cran-praise r-cran-processx r-cran-promises r-cran-ps r-cran-quadprog 244s r-cran-r6 r-cran-rappdirs r-cran-rcolorbrewer r-cran-rcpp r-cran-rlang 244s r-cran-rmarkdown r-cran-rprojroot r-cran-rsolnp r-cran-s7 r-cran-sandwich 244s r-cran-sass r-cran-scales r-cran-shiny r-cran-sourcetools r-cran-survival 244s r-cran-testthat r-cran-th.data r-cran-tinytex r-cran-truncnorm r-cran-vctrs 244s r-cran-viridislite r-cran-waldo r-cran-withr r-cran-xfun r-cran-xtable 244s r-cran-yaml r-cran-zoo unzip x11-common xdg-utils zip 244s 0 upgraded, 149 newly installed, 0 to remove and 0 not upgraded. 244s Need to get 157 MB of archives. 244s After this operation, 500 MB of additional disk space will be used. 244s Get:1 http://ftpmaster.internal/ubuntu resolute/main armhf libfreetype6 armhf 2.14.1+dfsg-2 [345 kB] 245s Get:2 http://ftpmaster.internal/ubuntu resolute/main armhf fonts-dejavu-mono all 2.37-8build1 [502 kB] 246s Get:3 http://ftpmaster.internal/ubuntu resolute/main armhf fonts-dejavu-core all 2.37-8build1 [834 kB] 247s Get:4 http://ftpmaster.internal/ubuntu resolute/main armhf fontconfig-config armhf 2.17.1-3ubuntu1 [38.5 kB] 247s Get:5 http://ftpmaster.internal/ubuntu resolute/main armhf libfontconfig1 armhf 2.17.1-3ubuntu1 [117 kB] 247s Get:6 http://ftpmaster.internal/ubuntu resolute/main armhf fontconfig armhf 2.17.1-3ubuntu1 [180 kB] 248s Get:7 http://ftpmaster.internal/ubuntu resolute/main armhf fonts-font-awesome all 5.0.10+really4.7.0~dfsg-4.1build1 [531 kB] 249s Get:8 http://ftpmaster.internal/ubuntu resolute/universe armhf fonts-glyphicons-halflings all 1.009~3.4.1+dfsg-6 [119 kB] 249s Get:9 http://ftpmaster.internal/ubuntu resolute/main armhf fonts-mathjax all 2.7.9+dfsg-1build1 [2283 kB] 253s Get:10 http://ftpmaster.internal/ubuntu resolute/main armhf javascript-common all 12+nmu1build1 [4864 B] 253s Get:11 http://ftpmaster.internal/ubuntu resolute/main armhf libblas3 armhf 3.12.1-7ubuntu1 [133 kB] 253s Get:12 http://ftpmaster.internal/ubuntu resolute/main armhf libpixman-1-0 armhf 0.46.4-1 [196 kB] 253s Get:13 http://ftpmaster.internal/ubuntu resolute/main armhf libxcb-render0 armhf 1.17.0-2ubuntu1 [15.5 kB] 253s Get:14 http://ftpmaster.internal/ubuntu resolute/main armhf libxcb-shm0 armhf 1.17.0-2ubuntu1 [5956 B] 253s Get:15 http://ftpmaster.internal/ubuntu resolute/main armhf libxrender1 armhf 1:0.9.12-1 [16.6 kB] 253s Get:16 http://ftpmaster.internal/ubuntu resolute/main armhf libcairo2 armhf 1.18.4-3 [489 kB] 254s Get:17 http://ftpmaster.internal/ubuntu resolute/main armhf libdatrie1 armhf 0.2.14-1 [16.4 kB] 254s Get:18 http://ftpmaster.internal/ubuntu resolute/main armhf libdeflate0 armhf 1.23-2build1 [38.8 kB] 254s Get:19 http://ftpmaster.internal/ubuntu resolute/main armhf libgfortran5 armhf 15.2.0-12ubuntu1 [334 kB] 255s Get:20 http://ftpmaster.internal/ubuntu resolute/main armhf libgomp1 armhf 15.2.0-12ubuntu1 [129 kB] 255s Get:21 http://ftpmaster.internal/ubuntu resolute/main armhf libgraphite2-3 armhf 1.3.14-11ubuntu1 [65.2 kB] 255s Get:22 http://ftpmaster.internal/ubuntu resolute/main armhf libharfbuzz0b armhf 12.3.2-1 [501 kB] 256s Get:23 http://ftpmaster.internal/ubuntu resolute/main armhf x11-common all 1:7.7+24ubuntu1 [22.4 kB] 256s Get:24 http://ftpmaster.internal/ubuntu resolute/main armhf libice6 armhf 2:1.1.1-1build1 [37.5 kB] 256s Get:25 http://ftpmaster.internal/ubuntu resolute/main armhf libjpeg-turbo8 armhf 2.1.5-4ubuntu3 [129 kB] 256s Get:26 http://ftpmaster.internal/ubuntu resolute/main armhf libjpeg8 armhf 8c-2ubuntu11 [2148 B] 256s Get:27 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-bootstrap all 3.4.1+dfsg-6 [129 kB] 256s Get:28 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-popper.js all 1.16.1+ds-6build1 [53.8 kB] 257s Get:29 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-bootstrap4 all 4.6.2+dfsg-1 [532 kB] 257s Get:30 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-d3 all 3.5.17-4build1 [136 kB] 258s Get:31 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-es5-shim all 4.6.7-2 [39.8 kB] 258s Get:32 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-highlight.js all 10.7.3+dfsg-2 [144 kB] 258s Get:33 http://ftpmaster.internal/ubuntu resolute/main armhf libjs-jquery all 3.7.1+dfsg+~3.5.33-1build1 [321 kB] 258s Get:34 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-jquery-datatables all 1.11.5+dfsg-2build1 [145 kB] 258s Get:35 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-sifter.js all 0.6.0+dfsg-3 [12.6 kB] 258s Get:36 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-microplugin.js all 0.0.3+dfsg-2 [3946 B] 258s Get:37 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-jquery-selectize.js all 0.12.6+dfsg-1.1 [51.0 kB] 259s Get:38 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-jquery-ui all 1.13.2+dfsg-1build1 [251 kB] 259s Get:39 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-json all 0~20221030+~1.0.8-1build1 [20.6 kB] 259s Get:40 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-prettify all 2015.12.04+dfsg-3 [41.4 kB] 259s Get:41 http://ftpmaster.internal/ubuntu resolute/main armhf liblapack3 armhf 3.12.1-7ubuntu1 [2090 kB] 263s Get:42 http://ftpmaster.internal/ubuntu resolute/main armhf liblerc4 armhf 4.0.0+ds-5ubuntu2 [162 kB] 263s Get:43 http://ftpmaster.internal/ubuntu resolute/main armhf liblua5.4-0 armhf 5.4.8-1 [134 kB] 263s Get:44 http://ftpmaster.internal/ubuntu resolute/main armhf libthai-data all 0.1.30-1 [155 kB] 263s Get:45 http://ftpmaster.internal/ubuntu resolute/main armhf libthai0 armhf 0.1.30-1 [15.4 kB] 263s Get:46 http://ftpmaster.internal/ubuntu resolute/main armhf libpango-1.0-0 armhf 1.57.0-1 [218 kB] 264s Get:47 http://ftpmaster.internal/ubuntu resolute/main armhf libpangoft2-1.0-0 armhf 1.57.0-1 [45.2 kB] 264s Get:48 http://ftpmaster.internal/ubuntu resolute/main armhf libpangocairo-1.0-0 armhf 1.57.0-1 [25.3 kB] 264s Get:49 http://ftpmaster.internal/ubuntu resolute/main armhf libpaper2 armhf 2.2.5-0.3build1 [16.3 kB] 264s Get:50 http://ftpmaster.internal/ubuntu resolute/main armhf libpaper-utils armhf 2.2.5-0.3build1 [14.2 kB] 264s Get:51 http://ftpmaster.internal/ubuntu resolute/main armhf libsharpyuv0 armhf 1.5.0-0.1build1 [16.3 kB] 264s Get:52 http://ftpmaster.internal/ubuntu resolute/main armhf libsm6 armhf 2:1.2.6-1build1 [15.3 kB] 264s Get:53 http://ftpmaster.internal/ubuntu resolute/main armhf libtcl8.6 armhf 8.6.17+dfsg-1build1 [918 kB] 265s Get:54 http://ftpmaster.internal/ubuntu resolute/main armhf libjbig0 armhf 2.1-6.1ubuntu3 [25.3 kB] 265s Get:55 http://ftpmaster.internal/ubuntu resolute/main armhf libwebp7 armhf 1.5.0-0.1build1 [189 kB] 266s Get:56 http://ftpmaster.internal/ubuntu resolute/main armhf libtiff6 armhf 4.7.0-3ubuntu3 [188 kB] 266s Get:57 http://ftpmaster.internal/ubuntu resolute/main armhf libxft2 armhf 2.3.6-1build2 [37.2 kB] 266s Get:58 http://ftpmaster.internal/ubuntu resolute/main armhf libxss1 armhf 1:1.2.3-1build4 [6328 B] 266s Get:59 http://ftpmaster.internal/ubuntu resolute/main armhf libtk8.6 armhf 8.6.17-1 [694 kB] 267s Get:60 http://ftpmaster.internal/ubuntu resolute/main armhf libxt6t64 armhf 1:1.2.1-1.3 [145 kB] 268s Get:61 http://ftpmaster.internal/ubuntu resolute/universe armhf node-bootstrap-sass all 3.4.3-2 [187 kB] 268s Get:62 http://ftpmaster.internal/ubuntu resolute/universe armhf node-html5shiv all 3.7.3+dfsg-5 [13.5 kB] 268s Get:63 http://ftpmaster.internal/ubuntu resolute/universe armhf node-normalize.css all 8.0.1-5.1 [10.4 kB] 268s Get:64 http://ftpmaster.internal/ubuntu resolute/universe armhf pandoc-data all 3.1.11.1-3build1 [78.8 kB] 268s Get:65 http://ftpmaster.internal/ubuntu resolute/universe armhf pandoc armhf 3.1.11.1+ds-4 [36.7 MB] 336s Get:66 http://ftpmaster.internal/ubuntu resolute/main armhf zip armhf 3.0-15ubuntu3 [164 kB] 336s Get:67 http://ftpmaster.internal/ubuntu resolute/main armhf unzip armhf 6.0-29ubuntu1 [167 kB] 336s Get:68 http://ftpmaster.internal/ubuntu resolute/main armhf xdg-utils all 1.2.1-2ubuntu2 [66.1 kB] 336s Get:69 http://ftpmaster.internal/ubuntu resolute/universe armhf r-base-core armhf 4.5.2-1ubuntu2 [28.5 MB] 388s Get:70 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-base64enc armhf 0.1-3-3build1 [28.2 kB] 388s Get:71 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-brio armhf 1.1.5-1 [37.9 kB] 388s Get:72 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rlang armhf 1.1.5-3 [1700 kB] 391s Get:73 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-fastmap armhf 1.2.0-1 [69.8 kB] 392s Get:74 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-cachem armhf 1.1.0-1 [73.8 kB] 392s Get:75 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-digest armhf 0.6.39-1 [211 kB] 392s Get:76 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-htmltools armhf 0.5.8.1-1 [372 kB] 393s Get:77 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-jquerylib all 0.1.4+dfsg-5 [13.7 kB] 393s Get:78 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-jsonlite armhf 1.9.1+dfsg-1 [440 kB] 394s Get:79 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-cli armhf 3.6.4-1 [1377 kB] 396s Get:80 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-lifecycle all 1.0.5+dfsg-1 [120 kB] 396s Get:81 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-memoise all 2.0.1-1build1 [54.5 kB] 396s Get:82 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-mime armhf 0.12-2 [35.5 kB] 396s Get:83 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-fs armhf 1.6.5+dfsg-1 [242 kB] 397s Get:84 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-r6 all 2.6.1-1 [101 kB] 397s Get:85 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rappdirs armhf 0.3.3-1build1 [49.3 kB] 397s Get:86 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-sass armhf 0.4.9+dfsg-1 [926 kB] 399s Get:87 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-bslib all 0.9.0+dfsg-3build1 [4560 kB] 407s Get:88 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-ps armhf 1.9.0-1 [403 kB] 408s Get:89 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-processx armhf 3.8.6-1 [359 kB] 409s Get:90 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-callr all 3.7.6-1 [458 kB] 410s Get:91 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-codetools all 0.2-20-1build1 [91.1 kB] 410s Get:92 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-commonmark armhf 1.9.5-1 [112 kB] 410s Get:93 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-crayon all 1.5.3-1 [165 kB] 410s Get:94 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-desc all 1.4.3-1 [359 kB] 411s Get:95 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-diffobj armhf 0.3.5-1build1 [1154 kB] 413s Get:96 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-glue armhf 1.8.0-1 [162 kB] 413s Get:97 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-gtable all 0.3.6+dfsg-1 [199 kB] 414s Get:98 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-isoband armhf 0.2.7-1 [1477 kB] 416s Get:99 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-s7 armhf 0.2.0-1 [328 kB] 417s Get:100 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-farver armhf 2.1.2-1 [1355 kB] 419s Get:101 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-labeling all 0.4.3-1 [62.1 kB] 419s Get:102 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rcolorbrewer all 1.1-3-1build2 [54.0 kB] 419s Get:103 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-viridislite all 0.4.3-1 [1088 kB] 421s Get:104 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-scales all 1.4.0-1 [725 kB] 422s Get:105 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-vctrs armhf 0.6.5-1 [1310 kB] 425s Get:106 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-withr all 3.0.2+dfsg-1 [214 kB] 425s Get:107 http://ftpmaster.internal/ubuntu resolute-proposed/universe armhf r-cran-ggplot2 all 4.0.2+dfsg-1 [4941 kB] 433s Get:108 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-lattice armhf 0.22-7-1 [1365 kB] 435s Get:109 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-mvtnorm armhf 1.3-3-1build1 [915 kB] 437s Get:110 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-dosefinding armhf 1.3-1-1 [971 kB] 438s Get:111 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-evaluate all 1.0.5-1 [117 kB] 439s Get:112 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-fontawesome all 0.5.3-1 [1331 kB] 441s Get:113 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-xfun armhf 0.55+dfsg-1 [589 kB] 442s Get:114 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-highr all 0.11+dfsg-1 [38.5 kB] 442s Get:115 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-littler armhf 0.3.22-1 [81.0 kB] 442s Get:116 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-pkgkitten all 0.2.4-1 [27.2 kB] 442s Get:117 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rcpp armhf 1.1.0-1 [2009 kB] 445s Get:118 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-later armhf 1.4.1+dfsg-1 [141 kB] 445s Get:119 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-magrittr armhf 2.0.3-1 [154 kB] 446s Get:120 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-promises armhf 1.3.2+dfsg-1 [288 kB] 446s Get:121 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-httpuv armhf 1.6.15+dfsg-1 [480 kB] 447s Get:122 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-yaml armhf 2.3.10-1 [101 kB] 447s Get:123 http://ftpmaster.internal/ubuntu resolute/main armhf libjs-mathjax all 2.7.9+dfsg-1build1 [6017 kB] 458s Get:124 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-knitr all 1.51+dfsg-1 [847 kB] 459s Get:125 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-mass armhf 7.3-65-1 [1108 kB] 461s Get:126 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-matrix armhf 1.7-4-1 [4139 kB] 468s Get:127 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-survival armhf 3.8-6-1 [8253 kB] 481s Get:128 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-th.data all 1.1-5-1 [8740 kB] 497s Get:129 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-zoo armhf 1.8-15-1 [1025 kB] 499s Get:130 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-sandwich all 3.1-1-1build1 [1483 kB] 501s Get:131 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-multcomp all 1.4-29-1 [617 kB] 502s Get:132 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-nlme armhf 3.1.168-1 [2304 kB] 506s Get:133 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-numderiv all 2016.8-1.1-3build1 [116 kB] 506s Get:134 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-pkgbuild all 1.4.8-1 [219 kB] 507s Get:135 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rprojroot all 2.1.1-1 [131 kB] 507s Get:136 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-pkgload all 1.4.1-1 [252 kB] 507s Get:137 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-praise all 1.0.0-4build2 [20.9 kB] 507s Get:138 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-quadprog armhf 1.5-8-1build2 [29.8 kB] 507s Get:139 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-tinytex all 0.58-1 [148 kB] 508s Get:140 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-modernizr all 3.13.0-0.1build1 [100 kB] 508s Get:141 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-xtable all 1:1.8-4-2build1 [691 kB] 509s Get:142 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-sourcetools armhf 0.1.7-1-1 [45.7 kB] 509s Get:143 http://ftpmaster.internal/ubuntu resolute/universe armhf libjs-twitter-bootstrap-datepicker all 1.3.1+dfsg1-4.1 [28.5 kB] 509s Get:144 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-shiny all 1.10.0+dfsg-2 [3124 kB] 515s Get:145 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rmarkdown all 2.30+dfsg-1 [1501 kB] 517s Get:146 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-truncnorm armhf 1.0-9-2 [24.0 kB] 517s Get:147 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-rsolnp all 1.16+dfsg-4build2 [248 kB] 517s Get:148 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-waldo all 0.6.2-1 [153 kB] 517s Get:149 http://ftpmaster.internal/ubuntu resolute/universe armhf r-cran-testthat armhf 3.2.3-1 [1633 kB] 521s Preconfiguring packages ... 521s Fetched 157 MB in 4min 36s (568 kB/s) 521s Selecting previously unselected package libfreetype6:armhf. 521s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 68686 files and directories currently installed.) 521s Preparing to unpack .../000-libfreetype6_2.14.1+dfsg-2_armhf.deb ... 521s Unpacking libfreetype6:armhf (2.14.1+dfsg-2) ... 521s Selecting previously unselected package fonts-dejavu-mono. 521s Preparing to unpack .../001-fonts-dejavu-mono_2.37-8build1_all.deb ... 521s Unpacking fonts-dejavu-mono (2.37-8build1) ... 521s Selecting previously unselected package fonts-dejavu-core. 521s Preparing to unpack .../002-fonts-dejavu-core_2.37-8build1_all.deb ... 521s Unpacking fonts-dejavu-core (2.37-8build1) ... 521s Selecting previously unselected package fontconfig-config. 521s Preparing to unpack .../003-fontconfig-config_2.17.1-3ubuntu1_armhf.deb ... 521s Unpacking fontconfig-config (2.17.1-3ubuntu1) ... 521s Selecting previously unselected package libfontconfig1:armhf. 521s Preparing to unpack .../004-libfontconfig1_2.17.1-3ubuntu1_armhf.deb ... 521s Unpacking libfontconfig1:armhf (2.17.1-3ubuntu1) ... 521s Selecting previously unselected package fontconfig. 521s Preparing to unpack .../005-fontconfig_2.17.1-3ubuntu1_armhf.deb ... 521s Unpacking fontconfig (2.17.1-3ubuntu1) ... 521s Selecting previously unselected package fonts-font-awesome. 521s Preparing to unpack .../006-fonts-font-awesome_5.0.10+really4.7.0~dfsg-4.1build1_all.deb ... 521s Unpacking fonts-font-awesome (5.0.10+really4.7.0~dfsg-4.1build1) ... 521s Selecting previously unselected package fonts-glyphicons-halflings. 521s Preparing to unpack .../007-fonts-glyphicons-halflings_1.009~3.4.1+dfsg-6_all.deb ... 521s Unpacking fonts-glyphicons-halflings (1.009~3.4.1+dfsg-6) ... 521s Selecting previously unselected package fonts-mathjax. 521s Preparing to unpack .../008-fonts-mathjax_2.7.9+dfsg-1build1_all.deb ... 521s Unpacking fonts-mathjax (2.7.9+dfsg-1build1) ... 522s Selecting previously unselected package javascript-common. 522s Preparing to unpack .../009-javascript-common_12+nmu1build1_all.deb ... 522s Unpacking javascript-common (12+nmu1build1) ... 522s Selecting previously unselected package libblas3:armhf. 522s Preparing to unpack .../010-libblas3_3.12.1-7ubuntu1_armhf.deb ... 522s Unpacking libblas3:armhf (3.12.1-7ubuntu1) ... 522s Selecting previously unselected package libpixman-1-0:armhf. 522s Preparing to unpack .../011-libpixman-1-0_0.46.4-1_armhf.deb ... 522s Unpacking libpixman-1-0:armhf (0.46.4-1) ... 522s Selecting previously unselected package libxcb-render0:armhf. 522s Preparing to unpack .../012-libxcb-render0_1.17.0-2ubuntu1_armhf.deb ... 522s Unpacking libxcb-render0:armhf (1.17.0-2ubuntu1) ... 522s Selecting previously unselected package libxcb-shm0:armhf. 522s Preparing to unpack .../013-libxcb-shm0_1.17.0-2ubuntu1_armhf.deb ... 522s Unpacking libxcb-shm0:armhf (1.17.0-2ubuntu1) ... 522s Selecting previously unselected package libxrender1:armhf. 522s Preparing to unpack .../014-libxrender1_1%3a0.9.12-1_armhf.deb ... 522s Unpacking libxrender1:armhf (1:0.9.12-1) ... 522s Selecting previously unselected package libcairo2:armhf. 522s Preparing to unpack .../015-libcairo2_1.18.4-3_armhf.deb ... 522s Unpacking libcairo2:armhf (1.18.4-3) ... 522s Selecting previously unselected package libdatrie1:armhf. 522s Preparing to unpack .../016-libdatrie1_0.2.14-1_armhf.deb ... 522s Unpacking libdatrie1:armhf (0.2.14-1) ... 522s Selecting previously unselected package libdeflate0:armhf. 522s Preparing to unpack .../017-libdeflate0_1.23-2build1_armhf.deb ... 522s Unpacking libdeflate0:armhf (1.23-2build1) ... 522s Selecting previously unselected package libgfortran5:armhf. 522s Preparing to unpack .../018-libgfortran5_15.2.0-12ubuntu1_armhf.deb ... 522s Unpacking libgfortran5:armhf (15.2.0-12ubuntu1) ... 522s Selecting previously unselected package libgomp1:armhf. 522s Preparing to unpack .../019-libgomp1_15.2.0-12ubuntu1_armhf.deb ... 522s Unpacking libgomp1:armhf (15.2.0-12ubuntu1) ... 522s Selecting previously unselected package libgraphite2-3:armhf. 522s Preparing to unpack .../020-libgraphite2-3_1.3.14-11ubuntu1_armhf.deb ... 522s Unpacking libgraphite2-3:armhf (1.3.14-11ubuntu1) ... 522s Selecting previously unselected package libharfbuzz0b:armhf. 522s Preparing to unpack .../021-libharfbuzz0b_12.3.2-1_armhf.deb ... 522s Unpacking libharfbuzz0b:armhf (12.3.2-1) ... 522s Selecting previously unselected package x11-common. 522s Preparing to unpack .../022-x11-common_1%3a7.7+24ubuntu1_all.deb ... 522s Unpacking x11-common (1:7.7+24ubuntu1) ... 522s Selecting previously unselected package libice6:armhf. 522s Preparing to unpack .../023-libice6_2%3a1.1.1-1build1_armhf.deb ... 522s Unpacking libice6:armhf (2:1.1.1-1build1) ... 522s Selecting previously unselected package libjpeg-turbo8:armhf. 522s Preparing to unpack .../024-libjpeg-turbo8_2.1.5-4ubuntu3_armhf.deb ... 522s Unpacking libjpeg-turbo8:armhf (2.1.5-4ubuntu3) ... 522s Selecting previously unselected package libjpeg8:armhf. 522s Preparing to unpack .../025-libjpeg8_8c-2ubuntu11_armhf.deb ... 522s Unpacking libjpeg8:armhf (8c-2ubuntu11) ... 522s Selecting previously unselected package libjs-bootstrap. 522s Preparing to unpack .../026-libjs-bootstrap_3.4.1+dfsg-6_all.deb ... 522s Unpacking libjs-bootstrap (3.4.1+dfsg-6) ... 522s Selecting previously unselected package libjs-popper.js. 522s Preparing to unpack .../027-libjs-popper.js_1.16.1+ds-6build1_all.deb ... 522s Unpacking libjs-popper.js (1.16.1+ds-6build1) ... 522s Selecting previously unselected package libjs-bootstrap4. 522s Preparing to unpack .../028-libjs-bootstrap4_4.6.2+dfsg-1_all.deb ... 522s Unpacking libjs-bootstrap4 (4.6.2+dfsg-1) ... 522s Selecting previously unselected package libjs-d3. 522s Preparing to unpack .../029-libjs-d3_3.5.17-4build1_all.deb ... 522s Unpacking libjs-d3 (3.5.17-4build1) ... 522s Selecting previously unselected package libjs-es5-shim. 522s Preparing to unpack .../030-libjs-es5-shim_4.6.7-2_all.deb ... 522s Unpacking libjs-es5-shim (4.6.7-2) ... 522s Selecting previously unselected package libjs-highlight.js. 522s Preparing to unpack .../031-libjs-highlight.js_10.7.3+dfsg-2_all.deb ... 522s Unpacking libjs-highlight.js (10.7.3+dfsg-2) ... 522s Selecting previously unselected package libjs-jquery. 522s Preparing to unpack .../032-libjs-jquery_3.7.1+dfsg+~3.5.33-1build1_all.deb ... 522s Unpacking libjs-jquery (3.7.1+dfsg+~3.5.33-1build1) ... 523s Selecting previously unselected package libjs-jquery-datatables. 523s Preparing to unpack .../033-libjs-jquery-datatables_1.11.5+dfsg-2build1_all.deb ... 523s Unpacking libjs-jquery-datatables (1.11.5+dfsg-2build1) ... 523s Selecting previously unselected package libjs-sifter.js. 523s Preparing to unpack .../034-libjs-sifter.js_0.6.0+dfsg-3_all.deb ... 523s Unpacking libjs-sifter.js (0.6.0+dfsg-3) ... 523s Selecting previously unselected package libjs-microplugin.js. 523s Preparing to unpack .../035-libjs-microplugin.js_0.0.3+dfsg-2_all.deb ... 523s Unpacking libjs-microplugin.js (0.0.3+dfsg-2) ... 523s Selecting previously unselected package libjs-jquery-selectize.js. 523s Preparing to unpack .../036-libjs-jquery-selectize.js_0.12.6+dfsg-1.1_all.deb ... 523s Unpacking libjs-jquery-selectize.js (0.12.6+dfsg-1.1) ... 523s Selecting previously unselected package libjs-jquery-ui. 523s Preparing to unpack .../037-libjs-jquery-ui_1.13.2+dfsg-1build1_all.deb ... 523s Unpacking libjs-jquery-ui (1.13.2+dfsg-1build1) ... 523s Selecting previously unselected package libjs-json. 523s Preparing to unpack .../038-libjs-json_0~20221030+~1.0.8-1build1_all.deb ... 523s Unpacking libjs-json (0~20221030+~1.0.8-1build1) ... 523s Selecting previously unselected package libjs-prettify. 523s Preparing to unpack .../039-libjs-prettify_2015.12.04+dfsg-3_all.deb ... 523s Unpacking libjs-prettify (2015.12.04+dfsg-3) ... 523s Selecting previously unselected package liblapack3:armhf. 523s Preparing to unpack .../040-liblapack3_3.12.1-7ubuntu1_armhf.deb ... 523s Unpacking liblapack3:armhf (3.12.1-7ubuntu1) ... 523s Selecting previously unselected package liblerc4:armhf. 523s Preparing to unpack .../041-liblerc4_4.0.0+ds-5ubuntu2_armhf.deb ... 523s Unpacking liblerc4:armhf (4.0.0+ds-5ubuntu2) ... 523s Selecting previously unselected package liblua5.4-0:armhf. 523s Preparing to unpack .../042-liblua5.4-0_5.4.8-1_armhf.deb ... 523s Unpacking liblua5.4-0:armhf (5.4.8-1) ... 523s Selecting previously unselected package libthai-data. 523s Preparing to unpack .../043-libthai-data_0.1.30-1_all.deb ... 523s Unpacking libthai-data (0.1.30-1) ... 523s Selecting previously unselected package libthai0:armhf. 523s Preparing to unpack .../044-libthai0_0.1.30-1_armhf.deb ... 523s Unpacking libthai0:armhf (0.1.30-1) ... 523s Selecting previously unselected package libpango-1.0-0:armhf. 523s Preparing to unpack .../045-libpango-1.0-0_1.57.0-1_armhf.deb ... 523s Unpacking libpango-1.0-0:armhf (1.57.0-1) ... 523s Selecting previously unselected package libpangoft2-1.0-0:armhf. 523s Preparing to unpack .../046-libpangoft2-1.0-0_1.57.0-1_armhf.deb ... 523s Unpacking libpangoft2-1.0-0:armhf (1.57.0-1) ... 523s Selecting previously unselected package libpangocairo-1.0-0:armhf. 523s Preparing to unpack .../047-libpangocairo-1.0-0_1.57.0-1_armhf.deb ... 523s Unpacking libpangocairo-1.0-0:armhf (1.57.0-1) ... 523s Selecting previously unselected package libpaper2:armhf. 523s Preparing to unpack .../048-libpaper2_2.2.5-0.3build1_armhf.deb ... 523s Unpacking libpaper2:armhf (2.2.5-0.3build1) ... 523s Selecting previously unselected package libpaper-utils. 523s Preparing to unpack .../049-libpaper-utils_2.2.5-0.3build1_armhf.deb ... 523s Unpacking libpaper-utils (2.2.5-0.3build1) ... 523s Selecting previously unselected package libsharpyuv0:armhf. 523s Preparing to unpack .../050-libsharpyuv0_1.5.0-0.1build1_armhf.deb ... 523s Unpacking libsharpyuv0:armhf (1.5.0-0.1build1) ... 523s Selecting previously unselected package libsm6:armhf. 523s Preparing to unpack .../051-libsm6_2%3a1.2.6-1build1_armhf.deb ... 523s Unpacking libsm6:armhf (2:1.2.6-1build1) ... 523s Selecting previously unselected package libtcl8.6:armhf. 523s Preparing to unpack .../052-libtcl8.6_8.6.17+dfsg-1build1_armhf.deb ... 523s Unpacking libtcl8.6:armhf (8.6.17+dfsg-1build1) ... 523s Selecting previously unselected package libjbig0:armhf. 523s Preparing to unpack .../053-libjbig0_2.1-6.1ubuntu3_armhf.deb ... 523s Unpacking libjbig0:armhf (2.1-6.1ubuntu3) ... 523s Selecting previously unselected package libwebp7:armhf. 523s Preparing to unpack .../054-libwebp7_1.5.0-0.1build1_armhf.deb ... 523s Unpacking libwebp7:armhf (1.5.0-0.1build1) ... 523s Selecting previously unselected package libtiff6:armhf. 523s Preparing to unpack .../055-libtiff6_4.7.0-3ubuntu3_armhf.deb ... 523s Unpacking libtiff6:armhf (4.7.0-3ubuntu3) ... 524s Selecting previously unselected package libxft2:armhf. 524s Preparing to unpack .../056-libxft2_2.3.6-1build2_armhf.deb ... 524s Unpacking libxft2:armhf (2.3.6-1build2) ... 524s Selecting previously unselected package libxss1:armhf. 524s Preparing to unpack .../057-libxss1_1%3a1.2.3-1build4_armhf.deb ... 524s Unpacking libxss1:armhf (1:1.2.3-1build4) ... 524s Selecting previously unselected package libtk8.6:armhf. 524s Preparing to unpack .../058-libtk8.6_8.6.17-1_armhf.deb ... 524s Unpacking libtk8.6:armhf (8.6.17-1) ... 524s Selecting previously unselected package libxt6t64:armhf. 524s Preparing to unpack .../059-libxt6t64_1%3a1.2.1-1.3_armhf.deb ... 524s Unpacking libxt6t64:armhf (1:1.2.1-1.3) ... 524s Selecting previously unselected package node-bootstrap-sass. 524s Preparing to unpack .../060-node-bootstrap-sass_3.4.3-2_all.deb ... 524s Unpacking node-bootstrap-sass (3.4.3-2) ... 524s Selecting previously unselected package node-html5shiv. 524s Preparing to unpack .../061-node-html5shiv_3.7.3+dfsg-5_all.deb ... 524s Unpacking node-html5shiv (3.7.3+dfsg-5) ... 524s Selecting previously unselected package node-normalize.css. 524s Preparing to unpack .../062-node-normalize.css_8.0.1-5.1_all.deb ... 524s Unpacking node-normalize.css (8.0.1-5.1) ... 524s Selecting previously unselected package pandoc-data. 524s Preparing to unpack .../063-pandoc-data_3.1.11.1-3build1_all.deb ... 524s Unpacking pandoc-data (3.1.11.1-3build1) ... 524s Selecting previously unselected package pandoc. 524s Preparing to unpack .../064-pandoc_3.1.11.1+ds-4_armhf.deb ... 524s Unpacking pandoc (3.1.11.1+ds-4) ... 525s Selecting previously unselected package zip. 525s Preparing to unpack .../065-zip_3.0-15ubuntu3_armhf.deb ... 525s Unpacking zip (3.0-15ubuntu3) ... 525s Selecting previously unselected package unzip. 525s Preparing to unpack .../066-unzip_6.0-29ubuntu1_armhf.deb ... 525s Unpacking unzip (6.0-29ubuntu1) ... 525s Selecting previously unselected package xdg-utils. 525s Preparing to unpack .../067-xdg-utils_1.2.1-2ubuntu2_all.deb ... 525s Unpacking xdg-utils (1.2.1-2ubuntu2) ... 525s Selecting previously unselected package r-base-core. 525s Preparing to unpack .../068-r-base-core_4.5.2-1ubuntu2_armhf.deb ... 525s Unpacking r-base-core (4.5.2-1ubuntu2) ... 526s Selecting previously unselected package r-cran-base64enc. 526s Preparing to unpack .../069-r-cran-base64enc_0.1-3-3build1_armhf.deb ... 526s Unpacking r-cran-base64enc (0.1-3-3build1) ... 526s Selecting previously unselected package r-cran-brio. 526s Preparing to unpack .../070-r-cran-brio_1.1.5-1_armhf.deb ... 526s Unpacking r-cran-brio (1.1.5-1) ... 526s Selecting previously unselected package r-cran-rlang. 526s Preparing to unpack .../071-r-cran-rlang_1.1.5-3_armhf.deb ... 526s Unpacking r-cran-rlang (1.1.5-3) ... 526s Selecting previously unselected package r-cran-fastmap. 526s Preparing to unpack .../072-r-cran-fastmap_1.2.0-1_armhf.deb ... 526s Unpacking r-cran-fastmap (1.2.0-1) ... 526s Selecting previously unselected package r-cran-cachem. 526s Preparing to unpack .../073-r-cran-cachem_1.1.0-1_armhf.deb ... 526s Unpacking r-cran-cachem (1.1.0-1) ... 526s Selecting previously unselected package r-cran-digest. 526s Preparing to unpack .../074-r-cran-digest_0.6.39-1_armhf.deb ... 526s Unpacking r-cran-digest (0.6.39-1) ... 526s Selecting previously unselected package r-cran-htmltools. 526s Preparing to unpack .../075-r-cran-htmltools_0.5.8.1-1_armhf.deb ... 526s Unpacking r-cran-htmltools (0.5.8.1-1) ... 526s Selecting previously unselected package r-cran-jquerylib. 526s Preparing to unpack .../076-r-cran-jquerylib_0.1.4+dfsg-5_all.deb ... 526s Unpacking r-cran-jquerylib (0.1.4+dfsg-5) ... 526s Selecting previously unselected package r-cran-jsonlite. 526s Preparing to unpack .../077-r-cran-jsonlite_1.9.1+dfsg-1_armhf.deb ... 526s Unpacking r-cran-jsonlite (1.9.1+dfsg-1) ... 526s Selecting previously unselected package r-cran-cli. 526s Preparing to unpack .../078-r-cran-cli_3.6.4-1_armhf.deb ... 526s Unpacking r-cran-cli (3.6.4-1) ... 526s Selecting previously unselected package r-cran-lifecycle. 526s Preparing to unpack .../079-r-cran-lifecycle_1.0.5+dfsg-1_all.deb ... 526s Unpacking r-cran-lifecycle (1.0.5+dfsg-1) ... 526s Selecting previously unselected package r-cran-memoise. 526s Preparing to unpack .../080-r-cran-memoise_2.0.1-1build1_all.deb ... 526s Unpacking r-cran-memoise (2.0.1-1build1) ... 526s Selecting previously unselected package r-cran-mime. 526s Preparing to unpack .../081-r-cran-mime_0.12-2_armhf.deb ... 526s Unpacking r-cran-mime (0.12-2) ... 526s Selecting previously unselected package r-cran-fs. 526s Preparing to unpack .../082-r-cran-fs_1.6.5+dfsg-1_armhf.deb ... 526s Unpacking r-cran-fs (1.6.5+dfsg-1) ... 527s Selecting previously unselected package r-cran-r6. 527s Preparing to unpack .../083-r-cran-r6_2.6.1-1_all.deb ... 527s Unpacking r-cran-r6 (2.6.1-1) ... 527s Selecting previously unselected package r-cran-rappdirs. 527s Preparing to unpack .../084-r-cran-rappdirs_0.3.3-1build1_armhf.deb ... 527s Unpacking r-cran-rappdirs (0.3.3-1build1) ... 527s Selecting previously unselected package r-cran-sass. 527s Preparing to unpack .../085-r-cran-sass_0.4.9+dfsg-1_armhf.deb ... 527s Unpacking r-cran-sass (0.4.9+dfsg-1) ... 527s Selecting previously unselected package r-cran-bslib. 527s Preparing to unpack .../086-r-cran-bslib_0.9.0+dfsg-3build1_all.deb ... 527s Unpacking r-cran-bslib (0.9.0+dfsg-3build1) ... 527s Selecting previously unselected package r-cran-ps. 527s Preparing to unpack .../087-r-cran-ps_1.9.0-1_armhf.deb ... 527s Unpacking r-cran-ps (1.9.0-1) ... 527s Selecting previously unselected package r-cran-processx. 527s Preparing to unpack .../088-r-cran-processx_3.8.6-1_armhf.deb ... 527s Unpacking r-cran-processx (3.8.6-1) ... 527s Selecting previously unselected package r-cran-callr. 527s Preparing to unpack .../089-r-cran-callr_3.7.6-1_all.deb ... 527s Unpacking r-cran-callr (3.7.6-1) ... 527s Selecting previously unselected package r-cran-codetools. 527s Preparing to unpack .../090-r-cran-codetools_0.2-20-1build1_all.deb ... 527s Unpacking r-cran-codetools (0.2-20-1build1) ... 527s Selecting previously unselected package r-cran-commonmark. 527s Preparing to unpack .../091-r-cran-commonmark_1.9.5-1_armhf.deb ... 527s Unpacking r-cran-commonmark (1.9.5-1) ... 527s Selecting previously unselected package r-cran-crayon. 527s Preparing to unpack .../092-r-cran-crayon_1.5.3-1_all.deb ... 527s Unpacking r-cran-crayon (1.5.3-1) ... 527s Selecting previously unselected package r-cran-desc. 527s Preparing to unpack .../093-r-cran-desc_1.4.3-1_all.deb ... 527s Unpacking r-cran-desc (1.4.3-1) ... 527s Selecting previously unselected package r-cran-diffobj. 527s Preparing to unpack .../094-r-cran-diffobj_0.3.5-1build1_armhf.deb ... 527s Unpacking r-cran-diffobj (0.3.5-1build1) ... 527s Selecting previously unselected package r-cran-glue. 527s Preparing to unpack .../095-r-cran-glue_1.8.0-1_armhf.deb ... 527s Unpacking r-cran-glue (1.8.0-1) ... 527s Selecting previously unselected package r-cran-gtable. 527s Preparing to unpack .../096-r-cran-gtable_0.3.6+dfsg-1_all.deb ... 527s Unpacking r-cran-gtable (0.3.6+dfsg-1) ... 527s Selecting previously unselected package r-cran-isoband. 527s Preparing to unpack .../097-r-cran-isoband_0.2.7-1_armhf.deb ... 527s Unpacking r-cran-isoband (0.2.7-1) ... 527s Selecting previously unselected package r-cran-s7. 527s Preparing to unpack .../098-r-cran-s7_0.2.0-1_armhf.deb ... 527s Unpacking r-cran-s7 (0.2.0-1) ... 527s Selecting previously unselected package r-cran-farver. 527s Preparing to unpack .../099-r-cran-farver_2.1.2-1_armhf.deb ... 527s Unpacking r-cran-farver (2.1.2-1) ... 528s Selecting previously unselected package r-cran-labeling. 528s Preparing to unpack .../100-r-cran-labeling_0.4.3-1_all.deb ... 528s Unpacking r-cran-labeling (0.4.3-1) ... 528s Selecting previously unselected package r-cran-rcolorbrewer. 528s Preparing to unpack .../101-r-cran-rcolorbrewer_1.1-3-1build2_all.deb ... 528s Unpacking r-cran-rcolorbrewer (1.1-3-1build2) ... 528s Selecting previously unselected package r-cran-viridislite. 528s Preparing to unpack .../102-r-cran-viridislite_0.4.3-1_all.deb ... 528s Unpacking r-cran-viridislite (0.4.3-1) ... 528s Selecting previously unselected package r-cran-scales. 528s Preparing to unpack .../103-r-cran-scales_1.4.0-1_all.deb ... 528s Unpacking r-cran-scales (1.4.0-1) ... 528s Selecting previously unselected package r-cran-vctrs. 528s Preparing to unpack .../104-r-cran-vctrs_0.6.5-1_armhf.deb ... 528s Unpacking r-cran-vctrs (0.6.5-1) ... 528s Selecting previously unselected package r-cran-withr. 528s Preparing to unpack .../105-r-cran-withr_3.0.2+dfsg-1_all.deb ... 528s Unpacking r-cran-withr (3.0.2+dfsg-1) ... 528s Selecting previously unselected package r-cran-ggplot2. 528s Preparing to unpack .../106-r-cran-ggplot2_4.0.2+dfsg-1_all.deb ... 528s Unpacking r-cran-ggplot2 (4.0.2+dfsg-1) ... 528s Selecting previously unselected package r-cran-lattice. 528s Preparing to unpack .../107-r-cran-lattice_0.22-7-1_armhf.deb ... 528s Unpacking r-cran-lattice (0.22-7-1) ... 528s Selecting previously unselected package r-cran-mvtnorm. 528s Preparing to unpack .../108-r-cran-mvtnorm_1.3-3-1build1_armhf.deb ... 528s Unpacking r-cran-mvtnorm (1.3-3-1build1) ... 528s Selecting previously unselected package r-cran-dosefinding. 528s Preparing to unpack .../109-r-cran-dosefinding_1.3-1-1_armhf.deb ... 528s Unpacking r-cran-dosefinding (1.3-1-1) ... 528s Selecting previously unselected package r-cran-evaluate. 528s Preparing to unpack .../110-r-cran-evaluate_1.0.5-1_all.deb ... 528s Unpacking r-cran-evaluate (1.0.5-1) ... 528s Selecting previously unselected package r-cran-fontawesome. 528s Preparing to unpack .../111-r-cran-fontawesome_0.5.3-1_all.deb ... 528s Unpacking r-cran-fontawesome (0.5.3-1) ... 528s Selecting previously unselected package r-cran-xfun. 528s Preparing to unpack .../112-r-cran-xfun_0.55+dfsg-1_armhf.deb ... 528s Unpacking r-cran-xfun (0.55+dfsg-1) ... 528s Selecting previously unselected package r-cran-highr. 528s Preparing to unpack .../113-r-cran-highr_0.11+dfsg-1_all.deb ... 528s Unpacking r-cran-highr (0.11+dfsg-1) ... 528s Selecting previously unselected package r-cran-littler. 528s Preparing to unpack .../114-r-cran-littler_0.3.22-1_armhf.deb ... 528s Unpacking r-cran-littler (0.3.22-1) ... 528s Selecting previously unselected package r-cran-pkgkitten. 528s Preparing to unpack .../115-r-cran-pkgkitten_0.2.4-1_all.deb ... 528s Unpacking r-cran-pkgkitten (0.2.4-1) ... 528s Selecting previously unselected package r-cran-rcpp. 528s Preparing to unpack .../116-r-cran-rcpp_1.1.0-1_armhf.deb ... 528s Unpacking r-cran-rcpp (1.1.0-1) ... 529s Selecting previously unselected package r-cran-later. 529s Preparing to unpack .../117-r-cran-later_1.4.1+dfsg-1_armhf.deb ... 529s Unpacking r-cran-later (1.4.1+dfsg-1) ... 529s Selecting previously unselected package r-cran-magrittr. 529s Preparing to unpack .../118-r-cran-magrittr_2.0.3-1_armhf.deb ... 529s Unpacking r-cran-magrittr (2.0.3-1) ... 529s Selecting previously unselected package r-cran-promises. 529s Preparing to unpack .../119-r-cran-promises_1.3.2+dfsg-1_armhf.deb ... 529s Unpacking r-cran-promises (1.3.2+dfsg-1) ... 529s Selecting previously unselected package r-cran-httpuv. 529s Preparing to unpack .../120-r-cran-httpuv_1.6.15+dfsg-1_armhf.deb ... 529s Unpacking r-cran-httpuv (1.6.15+dfsg-1) ... 529s Selecting previously unselected package r-cran-yaml. 529s Preparing to unpack .../121-r-cran-yaml_2.3.10-1_armhf.deb ... 529s Unpacking r-cran-yaml (2.3.10-1) ... 529s Selecting previously unselected package libjs-mathjax. 529s Preparing to unpack .../122-libjs-mathjax_2.7.9+dfsg-1build1_all.deb ... 529s Unpacking libjs-mathjax (2.7.9+dfsg-1build1) ... 529s Selecting previously unselected package r-cran-knitr. 529s Preparing to unpack .../123-r-cran-knitr_1.51+dfsg-1_all.deb ... 529s Unpacking r-cran-knitr (1.51+dfsg-1) ... 530s Selecting previously unselected package r-cran-mass. 530s Preparing to unpack .../124-r-cran-mass_7.3-65-1_armhf.deb ... 530s Unpacking r-cran-mass (7.3-65-1) ... 530s Selecting previously unselected package r-cran-matrix. 530s Preparing to unpack .../125-r-cran-matrix_1.7-4-1_armhf.deb ... 530s Unpacking r-cran-matrix (1.7-4-1) ... 530s Selecting previously unselected package r-cran-survival. 530s Preparing to unpack .../126-r-cran-survival_3.8-6-1_armhf.deb ... 530s Unpacking r-cran-survival (3.8-6-1) ... 530s Selecting previously unselected package r-cran-th.data. 530s Preparing to unpack .../127-r-cran-th.data_1.1-5-1_all.deb ... 530s Unpacking r-cran-th.data (1.1-5-1) ... 530s Selecting previously unselected package r-cran-zoo. 530s Preparing to unpack .../128-r-cran-zoo_1.8-15-1_armhf.deb ... 530s Unpacking r-cran-zoo (1.8-15-1) ... 530s Selecting previously unselected package r-cran-sandwich. 530s Preparing to unpack .../129-r-cran-sandwich_3.1-1-1build1_all.deb ... 530s Unpacking r-cran-sandwich (3.1-1-1build1) ... 530s Selecting previously unselected package r-cran-multcomp. 530s Preparing to unpack .../130-r-cran-multcomp_1.4-29-1_all.deb ... 530s Unpacking r-cran-multcomp (1.4-29-1) ... 530s Selecting previously unselected package r-cran-nlme. 530s Preparing to unpack .../131-r-cran-nlme_3.1.168-1_armhf.deb ... 530s Unpacking r-cran-nlme (3.1.168-1) ... 530s Selecting previously unselected package r-cran-numderiv. 530s Preparing to unpack .../132-r-cran-numderiv_2016.8-1.1-3build1_all.deb ... 530s Unpacking r-cran-numderiv (2016.8-1.1-3build1) ... 530s Selecting previously unselected package r-cran-pkgbuild. 530s Preparing to unpack .../133-r-cran-pkgbuild_1.4.8-1_all.deb ... 530s Unpacking r-cran-pkgbuild (1.4.8-1) ... 530s Selecting previously unselected package r-cran-rprojroot. 530s Preparing to unpack .../134-r-cran-rprojroot_2.1.1-1_all.deb ... 530s Unpacking r-cran-rprojroot (2.1.1-1) ... 530s Selecting previously unselected package r-cran-pkgload. 530s Preparing to unpack .../135-r-cran-pkgload_1.4.1-1_all.deb ... 530s Unpacking r-cran-pkgload (1.4.1-1) ... 530s Selecting previously unselected package r-cran-praise. 530s Preparing to unpack .../136-r-cran-praise_1.0.0-4build2_all.deb ... 530s Unpacking r-cran-praise (1.0.0-4build2) ... 530s Selecting previously unselected package r-cran-quadprog. 530s Preparing to unpack .../137-r-cran-quadprog_1.5-8-1build2_armhf.deb ... 530s Unpacking r-cran-quadprog (1.5-8-1build2) ... 530s Selecting previously unselected package r-cran-tinytex. 530s Preparing to unpack .../138-r-cran-tinytex_0.58-1_all.deb ... 530s Unpacking r-cran-tinytex (0.58-1) ... 531s Selecting previously unselected package libjs-modernizr. 531s Preparing to unpack .../139-libjs-modernizr_3.13.0-0.1build1_all.deb ... 531s Unpacking libjs-modernizr (3.13.0-0.1build1) ... 531s Selecting previously unselected package r-cran-xtable. 531s Preparing to unpack .../140-r-cran-xtable_1%3a1.8-4-2build1_all.deb ... 531s Unpacking r-cran-xtable (1:1.8-4-2build1) ... 531s Selecting previously unselected package r-cran-sourcetools. 531s Preparing to unpack .../141-r-cran-sourcetools_0.1.7-1-1_armhf.deb ... 531s Unpacking r-cran-sourcetools (0.1.7-1-1) ... 531s Selecting previously unselected package libjs-twitter-bootstrap-datepicker. 531s Preparing to unpack .../142-libjs-twitter-bootstrap-datepicker_1.3.1+dfsg1-4.1_all.deb ... 531s Unpacking libjs-twitter-bootstrap-datepicker (1.3.1+dfsg1-4.1) ... 531s Selecting previously unselected package r-cran-shiny. 531s Preparing to unpack .../143-r-cran-shiny_1.10.0+dfsg-2_all.deb ... 531s Unpacking r-cran-shiny (1.10.0+dfsg-2) ... 531s Selecting previously unselected package r-cran-rmarkdown. 531s Preparing to unpack .../144-r-cran-rmarkdown_2.30+dfsg-1_all.deb ... 531s Unpacking r-cran-rmarkdown (2.30+dfsg-1) ... 531s Selecting previously unselected package r-cran-truncnorm. 531s Preparing to unpack .../145-r-cran-truncnorm_1.0-9-2_armhf.deb ... 531s Unpacking r-cran-truncnorm (1.0-9-2) ... 531s Selecting previously unselected package r-cran-rsolnp. 531s Preparing to unpack .../146-r-cran-rsolnp_1.16+dfsg-4build2_all.deb ... 531s Unpacking r-cran-rsolnp (1.16+dfsg-4build2) ... 531s Selecting previously unselected package r-cran-waldo. 531s Preparing to unpack .../147-r-cran-waldo_0.6.2-1_all.deb ... 531s Unpacking r-cran-waldo (0.6.2-1) ... 531s Selecting previously unselected package r-cran-testthat. 531s Preparing to unpack .../148-r-cran-testthat_3.2.3-1_armhf.deb ... 531s Unpacking r-cran-testthat (3.2.3-1) ... 531s Setting up libjs-json (0~20221030+~1.0.8-1build1) ... 531s Setting up javascript-common (12+nmu1build1) ... 531s Setting up libgraphite2-3:armhf (1.3.14-11ubuntu1) ... 531s Setting up libpixman-1-0:armhf (0.46.4-1) ... 531s Setting up libsharpyuv0:armhf (1.5.0-0.1build1) ... 531s Setting up fonts-mathjax (2.7.9+dfsg-1build1) ... 531s Setting up liblerc4:armhf (4.0.0+ds-5ubuntu2) ... 531s Setting up libjs-mathjax (2.7.9+dfsg-1build1) ... 531s Setting up libxrender1:armhf (1:0.9.12-1) ... 531s Setting up libdatrie1:armhf (0.2.14-1) ... 531s Setting up libjs-popper.js (1.16.1+ds-6build1) ... 531s Setting up libxcb-render0:armhf (1.17.0-2ubuntu1) ... 531s Setting up libjs-sifter.js (0.6.0+dfsg-3) ... 531s Setting up fonts-glyphicons-halflings (1.009~3.4.1+dfsg-6) ... 531s Setting up unzip (6.0-29ubuntu1) ... 531s Setting up x11-common (1:7.7+24ubuntu1) ... 532s Setting up node-html5shiv (3.7.3+dfsg-5) ... 532s Setting up libdeflate0:armhf 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(0.11+dfsg-1) ... 535s Setting up r-cran-mass (7.3-65-1) ... 535s Setting up r-cran-rsolnp (1.16+dfsg-4build2) ... 535s Setting up r-cran-glue (1.8.0-1) ... 535s Setting up r-cran-xtable (1:1.8-4-2build1) ... 535s Setting up r-cran-cli (3.6.4-1) ... 535s Setting up r-cran-lifecycle (1.0.5+dfsg-1) ... 535s Setting up r-cran-rprojroot (2.1.1-1) ... 535s Setting up r-cran-fastmap (1.2.0-1) ... 535s Setting up r-cran-jsonlite (1.9.1+dfsg-1) ... 535s Setting up r-cran-s7 (0.2.0-1) ... 535s Setting up r-cran-mvtnorm (1.3-3-1build1) ... 535s Setting up r-cran-rcolorbrewer (1.1-3-1build2) ... 535s Setting up r-cran-isoband (0.2.7-1) ... 535s Setting up r-cran-waldo (0.6.2-1) ... 535s Setting up r-cran-scales (1.4.0-1) ... 535s Setting up r-cran-gtable (0.3.6+dfsg-1) ... 535s Setting up r-cran-zoo (1.8-15-1) ... 535s Setting up r-cran-later (1.4.1+dfsg-1) ... 535s Setting up r-cran-matrix (1.7-4-1) ... 535s Setting up r-cran-htmltools (0.5.8.1-1) ... 535s Setting up r-cran-tinytex (0.58-1) ... 535s Setting up r-cran-knitr (1.51+dfsg-1) ... 535s Setting up r-cran-cachem (1.1.0-1) ... 535s Setting up r-cran-sass (0.4.9+dfsg-1) ... 535s Setting up r-cran-vctrs (0.6.5-1) ... 535s Setting up r-cran-callr (3.7.6-1) ... 535s Setting up r-cran-ggplot2 (4.0.2+dfsg-1) ... 535s Setting up r-cran-desc (1.4.3-1) ... 535s Setting up r-cran-sandwich (3.1-1-1build1) ... 535s Setting up r-cran-fontawesome (0.5.3-1) ... 535s Setting up r-cran-survival (3.8-6-1) ... 535s Setting up r-cran-jquerylib (0.1.4+dfsg-5) ... 535s Setting up r-cran-th.data (1.1-5-1) ... 535s Setting up r-cran-memoise (2.0.1-1build1) ... 535s Setting up r-cran-promises (1.3.2+dfsg-1) ... 535s Setting up r-cran-multcomp (1.4-29-1) ... 535s Setting up r-cran-pkgbuild (1.4.8-1) ... 535s Setting up r-cran-pkgload (1.4.1-1) ... 535s Setting up r-cran-dosefinding (1.3-1-1) ... 535s Setting up r-cran-httpuv (1.6.15+dfsg-1) ... 535s Setting up r-cran-testthat (3.2.3-1) ... 535s Setting up r-cran-bslib (0.9.0+dfsg-3build1) ... 535s Setting up r-cran-shiny (1.10.0+dfsg-2) ... 535s Setting up r-cran-rmarkdown (2.30+dfsg-1) ... 535s Processing triggers for libc-bin (2.42-2ubuntu4) ... 535s Processing triggers for man-db (2.13.1-1build1) ... 535s Processing triggers for install-info (7.2-5) ... 544s autopkgtest [23:25:44]: test run-unit-test: [----------------------- 546s Loading required package: DoseFinding 547s Dose Response Model 547s 547s Model: linear 547s Fit-type: general 547s 547s Coefficients dose-response model 547s delta 547s 0.07484 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 3.472 547s Dose Response Model 547s 547s Model: linear 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 delta 547s 0.33400 0.07484 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 3.472 547s Dose Response Model 547s 547s Model: quadratic 547s Fit-type: general 547s 547s Coefficients dose-response model 547s b1 b2 547s 0.22800 -0.03811 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.9281 547s Dose Response Model 547s 547s Model: quadratic 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 b1 b2 547s 0.24950 0.22800 -0.03811 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.9281 547s Dose Response Model 547s 547s Model: linlog 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 delta 547s 0.47790 0.07728 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.1605 547s Dose Response Model 547s 547s Model: emax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s eMax ed50 547s 0.3771 0.3630 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.09815 547s Dose Response Model 547s 547s Model: emax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax ed50 547s 0.2221 0.3771 0.3630 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.09815 547s Dose Response Model 547s 547s Model: sigEmax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s eMax ed50 h 547s 0.4714 0.4880 0.5000 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.07825 547s Dose Response Model 547s 547s Model: sigEmax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax ed50 h 547s 0.2223 0.4714 0.4880 0.5000 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.07825 547s Dose Response Model 547s 547s Model: exponential 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e1 delta 547s 0.4391 8.0000 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 4.102 547s Dose Response Model 547s 547s Model: exponential 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 e1 delta 547s 0.3510 0.4391 8.0000 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 4.102 547s Dose Response Model 547s 547s Model: logistic 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax ed50 delta 547s -0.1095 0.6665 0.0040 0.4217 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.1951 547s Dose Response Model 547s 547s Model: betaMod 547s Fit-type: general 547s 547s Coefficients dose-response model 547s eMax delta1 delta2 547s 0.3468 0.2216 0.0500 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.0783 547s Dose Response Model 547s 547s Model: betaMod 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax delta1 delta2 547s 0.2222 0.3468 0.2216 0.0500 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.0783 547s Dose Response Model 547s 547s Model: linInt 547s Fit-type: general 547s 547s Coefficients dose-response model 547s d1 d2 d3 d4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0 547s Dose Response Model 547s 547s Model: linInt 547s Fit-type: general 547s 547s Coefficients dose-response model 547s d0 d1 d2 d3 d4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 1.484e-30 547s Dose Response Model 547s 547s Model: emax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s eMax ed50 547s 0.3771 0.3630 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.09815 547s Dose Response Model 547s 547s Model: emax 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax ed50 547s 0.2221 0.3771 0.3630 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.09815 547s Dose Response Model 547s 547s Model: betaMod 547s Fit-type: general 547s 547s Coefficients dose-response model 547s eMax delta1 delta2 547s 0.3468 0.2216 0.0500 547s 547s Fitted to: 547s 1 2 3 4 547s 0.2846 0.2965 0.3502 0.3480 547s 547s Generalized residual sum of squares: 0.0783 547s Dose Response Model 547s 547s Model: betaMod 547s Fit-type: general 547s 547s Coefficients dose-response model 547s e0 eMax delta1 delta2 547s 0.2222 0.3468 0.2216 0.0500 547s 547s Fitted to: 547s 0 1 2 3 4 547s 0.2220 0.5065 0.5185 0.5722 0.5700 547s 547s Generalized residual sum of squares: 0.0783 547s $fit 547s [1] 0.0000000 0.2756421 0.3165257 0.3387105 0.3466573 547s 547s $se.fit 547s [1] 0.0000000 0.1235753 0.1106156 0.1135736 0.1263900 547s 547s $fit 547s [1] 0.2756421 0.3165257 0.3387105 0.3466573 547s 547s $se.fit 547s [1] 0.1235753 0.1106156 0.1135736 0.1263900 547s 547s e0 eMax delta1 delta2 547s e0 0.0118410628 -0.008186899 0.003722514 -0.0008419768 547s eMax -0.0081868987 0.014334651 -0.016984400 -0.0239850502 547s delta1 0.0037225143 -0.016984400 0.475384247 0.3641344062 547s delta2 -0.0008419768 -0.023985050 0.364134406 0.3356088151 547s eMax delta1 delta2 547s eMax 0.01433465 -0.0169844 -0.02398505 547s delta1 -0.01698440 0.4753842 0.36413441 547s delta2 -0.02398505 0.3641344 0.33560882 548s Message: Setting predType to "ls-means" for "type = general" 548s $fit 548s [1] 0.2219856 0.5065390 0.5185323 0.5721580 0.5699850 548s 548s $se.fit 548s [1] 0.1088272 0.1048057 0.1044027 0.1046862 0.1088405 548s 548s $fit 548s [1] 0.0000000 0.2845534 0.2965467 0.3501724 0.3479994 548s 548s $se.fit 548s [1] 0.0000000 0.1252903 0.1265494 0.1279290 0.1273279 548s 548s Message: Setting predType to "effect-curve" for placebo-adjusted data 548s $fit 548s [1] 0.2845534 0.2965467 0.3501724 0.3479994 548s 548s $se.fit 548s [1] 0.1252903 0.1265494 0.1279290 0.1273279 548s 548s d0 d1 d2 d3 d4 548s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 548s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 548s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 548s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 548s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 548s d1 d2 d3 d4 548s d1 0.015697662 0.008221459 0.008223928 0.008215124 548s d2 0.008221459 0.016014746 0.008246506 0.008208911 548s d3 0.008223928 0.008246506 0.016365819 0.008204394 548s d4 0.008215124 0.008208911 0.008204394 0.016212400 548s d0 d1 d2 d3 d4 548s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 548s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 548s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 548s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 548s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 548s gender2 -0.005149393 -0.005062250 -0.004777264 -0.004570087 -0.005308813 548s gender2 548s d0 -0.005149393 548s d1 -0.005062250 548s d2 -0.004777264 548s d3 -0.004570087 548s d4 -0.005308813 548s gender2 0.007312139 548s d0 d1 d2 d3 d4 548s d0 0.00819461 0.000000000 0.000000000 0.000000000 0.0000000 548s d1 0.00000000 0.007459197 0.000000000 0.000000000 0.0000000 548s d2 0.00000000 0.000000000 0.007757564 0.000000000 0.0000000 548s d3 0.00000000 0.000000000 0.000000000 0.008080796 0.0000000 548s d4 0.00000000 0.000000000 0.000000000 0.000000000 0.0079701 548s d1 d2 d3 d4 548s d1 0.015697662 0.008221459 0.008223928 0.008215124 548s d2 0.008221459 0.016014746 0.008246506 0.008208911 548s d3 0.008223928 0.008246506 0.016365819 0.008204394 548s d4 0.008215124 0.008208911 0.008204394 0.016212400 548s $fit 548s [1] 0.2845534 0.2965467 0.3501724 0.3479994 548s 548s $se.fit 548s [1] 0.1252903 0.1265494 0.1279290 0.1273279 548s 548s testgFit.R passed 548s testplanMod.R passed 548s Loading required package: DoseFinding 549s [1] 0.5099184 549s Calculated TD - optimal design: 549s 0 18.75 549s 0.50003 0.49997 549s Calculated TD - optimal design: 549s 0 104.52 549s 0.49993 0.50006 549s [1] 0.4286171 549s Calculated TD - optimal design: 549s 0 101.57 150 549s 0.43958 0.50000 0.06041 549s Calculated TD - optimal design: 549s 0 37.29 64.44 150 549s 0.40070 0.45303 0.09933 0.04694 549s [1] 0.1853293 549s Calculated TD - optimal design: 549s 0 50.22 549s 0.5 0.5 550s Calculated TD - optimal design: 550s 0 0.49 25.2 108.07 550s 0.44787 0.47652 0.05213 0.02348 550s [1] 0.130092 550s Calculated TD - optimal design: 550s 0 27 94.89 150 550s 0.44879 0.47519 0.05121 0.02481 550s [1] 0.5013672 550s Calculated TD - optimal design: 550s 0 0.35 150 550s 0.49865 0.50000 0.00135 550s [1] 0.05572985 550s [1] 4.478701e-01 4.765233e-01 5.212994e-02 2.347673e-02 6.509032e-09 550s [1] 4.478701e-01 4.765233e-01 5.212991e-02 2.347669e-02 1.862896e-09 550s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 550s [1,] 0.246 0.142 0.122 0.000 0.000 0.241 0 0 0.249 550s [2,] 0.248 0.234 0.059 0.211 0.000 0.000 0 0 0.248 550s [3,] 0.247 0.000 0.000 0.224 0.081 0.203 0 0 0.246 550s [4,] 0.250 0.248 0.044 0.210 0.000 0.000 0 0 0.249 550s [5,] 0.250 0.248 0.191 0.064 0.000 0.000 0 0 0.247 550s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 550s [1,] 0.49 0.01 0.00 0.00 0.00 0.00 0.36 0.14 0.00 550s [2,] 0.48 0.02 0.00 0.32 0.18 0.00 0.00 0.00 0.00 550s [3,] 0.21 0.29 0.00 0.00 0.00 0.46 0.04 0.00 0.00 550s [4,] 0.50 0.00 0.49 0.01 0.00 0.00 0.00 0.00 0.00 550s [5,] 0.49 0.02 0.48 0.00 0.00 0.00 0.00 0.00 0.01 550s [1] 0.8823949 551s Calculated D - optimal design: 551s 0 1 551s 0.5 0.5 551s Calculated TD - optimal design: 551s 0 0.25 0.5 1 551s 0.48951 0.35517 0.14483 0.01049 551s testsDesign.R passed 551s Loading required package: DoseFinding 552s [1] 3714.641 552s [1] 3714.641 552s Dose Response Model 552s 552s Model: betaMod 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -23.368 -3.727 0.129 3.894 16.152 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 10.80 0.565 552s eMax 7.41 0.692 552s delta1 2.24 0.589 552s delta2 1.00 0.328 552s 552s Residual standard error: 5.64 552s Degrees of freedom: 585 552s 552s Formula: y ~ betaMod(x, e0, emax, delta1, delta2, 1.2 * max(datset$x)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s e0 10.7964 0.5653 19.098 < 2e-16 *** 552s emax 7.4106 0.6917 10.714 < 2e-16 *** 552s delta1 2.2357 0.5885 3.799 0.000161 *** 552s delta2 1.0047 0.3277 3.066 0.002271 ** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 5.637 on 585 degrees of freedom 552s 552s Number of iterations to convergence: 6 552s Achieved convergence tolerance: 4.028e-06 552s 552s e0 eMax delta1 delta2 552s e0 0.31958673 -0.28252697 0.20809234 0.09247897 552s eMax -0.28252697 0.47843297 -0.04177476 0.01244179 552s delta1 0.20809234 -0.04177476 0.34639417 0.18051781 552s delta2 0.09247897 0.01244179 0.18051781 0.10741017 552s e0 emax delta1 delta2 552s e0 0.31959066 -0.28253052 0.20808969 0.09247786 552s emax -0.28253052 0.47843381 -0.04177516 0.01244118 552s delta1 0.20808969 -0.04177516 0.34638195 0.18051234 552s delta2 0.09247786 0.01244118 0.18051234 0.10740756 552s $fit 552s [1] 6.0578751 6.8058158 7.2227652 6.0578751 3.1444084 6.8058158 7.2227652 552s [8] 3.1444084 6.0578751 0.0000000 6.0578751 6.0578751 7.2227652 3.1444084 552s [15] 0.8440180 0.0000000 6.0578751 3.1444084 3.1444084 0.0000000 7.2227652 552s [22] 0.0000000 7.2227652 6.8058158 6.8058158 3.1444084 6.8058158 6.8058158 552s [29] 3.1444084 6.0578751 7.2227652 6.8058158 3.1444084 3.1444084 3.1444084 552s [36] 0.0000000 0.0000000 3.1444084 6.8058158 3.1444084 3.1444084 0.8440180 552s [43] 3.1444084 6.0578751 3.1444084 6.0578751 0.8440180 7.2227652 0.8440180 552s [50] 0.8440180 0.0000000 7.2227652 6.8058158 6.8058158 7.2227652 3.1444084 552s [57] 7.2227652 6.8058158 0.8440180 0.8440180 3.1444084 0.0000000 7.2227652 552s [64] 6.8058158 6.8058158 6.8058158 0.0000000 7.2227652 3.1444084 6.0578751 552s [71] 0.0000000 0.8440180 0.8440180 6.8058158 3.1444084 3.1444084 6.0578751 552s [78] 0.0000000 6.0578751 6.8058158 6.8058158 3.1444084 3.1444084 3.1444084 552s [85] 3.1444084 7.2227652 6.8058158 0.8440180 0.0000000 0.8440180 7.2227652 552s [92] 6.8058158 3.1444084 7.2227652 6.0578751 6.8058158 6.0578751 6.8058158 552s [99] 6.8058158 6.8058158 3.1444084 6.0578751 6.8058158 0.0000000 6.0578751 552s [106] 6.8058158 0.0000000 6.8058158 3.1444084 3.1444084 0.8440180 6.8058158 552s [113] 6.0578751 3.1444084 0.1731496 6.0578751 6.0578751 0.0000000 6.8058158 552s [120] 0.0000000 0.0000000 6.8058158 0.1731496 0.8440180 0.0000000 6.0578751 552s [127] 6.8058158 3.1444084 6.0578751 0.8440180 6.8058158 0.8440180 7.2227652 552s [134] 6.8058158 3.1444084 6.0578751 6.8058158 7.2227652 6.8058158 0.1731496 552s [141] 6.8058158 6.8058158 0.8440180 6.8058158 6.0578751 7.2227652 6.8058158 552s [148] 3.1444084 3.1444084 0.0000000 6.0578751 3.1444084 0.0000000 3.1444084 552s [155] 6.8058158 7.2227652 6.8058158 0.0000000 0.0000000 0.8440180 3.1444084 552s [162] 0.0000000 0.1731496 3.1444084 3.1444084 6.0578751 0.0000000 0.8440180 552s [169] 0.0000000 3.1444084 3.1444084 6.0578751 6.0578751 0.0000000 7.2227652 552s [176] 0.8440180 0.0000000 6.0578751 0.0000000 7.2227652 0.0000000 3.1444084 552s [183] 6.0578751 6.0578751 3.1444084 3.1444084 0.1731496 7.2227652 3.1444084 552s [190] 0.8440180 7.2227652 7.2227652 0.8440180 0.0000000 7.2227652 3.1444084 552s [197] 7.2227652 7.2227652 0.1731496 3.1444084 0.0000000 7.2227652 3.1444084 552s [204] 6.8058158 6.8058158 7.2227652 6.8058158 7.2227652 0.8440180 6.0578751 552s [211] 3.1444084 3.1444084 3.1444084 0.0000000 0.0000000 6.0578751 6.0578751 552s [218] 3.1444084 3.1444084 0.1731496 7.2227652 7.2227652 0.0000000 0.8440180 552s [225] 7.2227652 0.8440180 3.1444084 0.8440180 0.0000000 7.2227652 3.1444084 552s [232] 6.8058158 6.8058158 3.1444084 0.8440180 6.0578751 0.8440180 0.0000000 552s [239] 0.0000000 6.8058158 7.2227652 6.8058158 6.0578751 3.1444084 7.2227652 552s [246] 6.8058158 3.1444084 7.2227652 0.8440180 0.8440180 7.2227652 6.0578751 552s [253] 0.1731496 7.2227652 6.8058158 6.8058158 7.2227652 6.8058158 6.0578751 552s [260] 6.8058158 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 0.8440180 552s [267] 6.8058158 3.1444084 3.1444084 0.8440180 3.1444084 0.8440180 0.0000000 552s [274] 3.1444084 0.8440180 0.8440180 0.1731496 6.0578751 6.0578751 0.8440180 552s [281] 0.0000000 0.0000000 0.0000000 6.0578751 0.0000000 3.1444084 3.1444084 552s [288] 0.0000000 0.8440180 6.0578751 0.0000000 6.0578751 7.2227652 0.8440180 552s [295] 7.2227652 6.8058158 0.8440180 0.1731496 7.2227652 7.2227652 0.0000000 552s [302] 6.0578751 6.8058158 7.2227652 0.0000000 6.0578751 6.0578751 6.8058158 552s [309] 0.0000000 0.8440180 6.0578751 6.8058158 6.8058158 3.1444084 0.8440180 552s [316] 6.8058158 3.1444084 7.2227652 6.0578751 0.8440180 3.1444084 0.8440180 552s [323] 7.2227652 6.0578751 6.0578751 7.2227652 3.1444084 6.0578751 6.8058158 552s [330] 0.8440180 0.8440180 6.8058158 6.8058158 7.2227652 0.8440180 3.1444084 552s [337] 3.1444084 6.0578751 6.0578751 0.0000000 3.1444084 6.8058158 0.8440180 552s [344] 3.1444084 6.0578751 7.2227652 3.1444084 3.1444084 0.1731496 6.0578751 552s [351] 7.2227652 7.2227652 3.1444084 6.0578751 3.1444084 6.0578751 3.1444084 552s [358] 6.0578751 3.1444084 7.2227652 0.8440180 3.1444084 6.8058158 0.8440180 552s [365] 3.1444084 0.1731496 6.8058158 3.1444084 6.8058158 7.2227652 3.1444084 552s [372] 6.8058158 6.8058158 3.1444084 0.0000000 0.8440180 0.8440180 6.8058158 552s [379] 0.0000000 7.2227652 0.8440180 0.8440180 6.0578751 3.1444084 0.8440180 552s [386] 7.2227652 3.1444084 7.2227652 6.8058158 3.1444084 3.1444084 6.8058158 552s [393] 6.0578751 3.1444084 6.8058158 0.0000000 6.8058158 0.8440180 0.0000000 552s [400] 3.1444084 6.8058158 0.8440180 6.0578751 6.0578751 0.1731496 6.0578751 552s [407] 0.8440180 3.1444084 0.8440180 3.1444084 3.1444084 6.8058158 0.8440180 552s [414] 6.8058158 7.2227652 0.0000000 6.8058158 0.8440180 0.0000000 7.2227652 552s [421] 6.8058158 3.1444084 3.1444084 6.8058158 6.8058158 6.0578751 6.0578751 552s [428] 6.0578751 7.2227652 0.1731496 7.2227652 6.8058158 0.0000000 3.1444084 552s [435] 7.2227652 6.8058158 6.8058158 0.8440180 0.0000000 3.1444084 7.2227652 552s [442] 6.8058158 6.0578751 3.1444084 6.0578751 7.2227652 6.0578751 7.2227652 552s [449] 0.0000000 7.2227652 7.2227652 0.8440180 6.0578751 6.8058158 0.0000000 552s [456] 0.8440180 6.0578751 0.1731496 3.1444084 7.2227652 7.2227652 6.0578751 552s [463] 6.0578751 3.1444084 0.1731496 7.2227652 6.8058158 0.8440180 0.0000000 552s [470] 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 7.2227652 0.8440180 552s [477] 3.1444084 7.2227652 7.2227652 0.1731496 3.1444084 7.2227652 7.2227652 552s [484] 3.1444084 6.8058158 0.0000000 7.2227652 6.0578751 0.8440180 3.1444084 552s [491] 7.2227652 7.2227652 6.0578751 3.1444084 7.2227652 6.0578751 0.0000000 552s [498] 0.8440180 6.0578751 6.8058158 3.1444084 6.0578751 0.0000000 7.2227652 552s [505] 3.1444084 0.0000000 0.8440180 7.2227652 6.8058158 6.8058158 3.1444084 552s [512] 6.8058158 0.1731496 0.0000000 3.1444084 3.1444084 3.1444084 6.8058158 552s [519] 6.8058158 0.0000000 6.8058158 6.8058158 3.1444084 7.2227652 3.1444084 552s [526] 0.8440180 0.8440180 7.2227652 6.0578751 6.0578751 3.1444084 6.8058158 552s [533] 7.2227652 6.0578751 6.8058158 3.1444084 3.1444084 3.1444084 7.2227652 552s [540] 0.0000000 0.0000000 6.8058158 3.1444084 0.1731496 0.0000000 6.0578751 552s [547] 7.2227652 6.0578751 6.0578751 7.2227652 6.0578751 6.0578751 6.8058158 552s [554] 0.0000000 0.0000000 3.1444084 6.0578751 7.2227652 7.2227652 3.1444084 552s [561] 3.1444084 6.8058158 7.2227652 6.8058158 6.8058158 0.0000000 6.8058158 552s [568] 3.1444084 7.2227652 0.8440180 0.0000000 3.1444084 0.8440180 6.8058158 552s [575] 7.2227652 3.1444084 6.0578751 0.8440180 6.8058158 3.1444084 0.0000000 552s [582] 7.2227652 6.8058158 0.8440180 6.0578751 3.1444084 6.8058158 0.8440180 552s [589] 6.0578751 552s 552s $se.fit 552s [1] 0.7643614 0.6580335 0.7488551 0.7643614 0.7997224 0.6580335 0.7488551 552s [8] 0.7997224 0.7643614 0.0000000 0.7643614 0.7643614 0.7488551 0.7997224 552s [15] 0.4790120 0.0000000 0.7643614 0.7997224 0.7997224 0.0000000 0.7488551 552s [22] 0.0000000 0.7488551 0.6580335 0.6580335 0.7997224 0.6580335 0.6580335 552s [29] 0.7997224 0.7643614 0.7488551 0.6580335 0.7997224 0.7997224 0.7997224 552s [36] 0.0000000 0.0000000 0.7997224 0.6580335 0.7997224 0.7997224 0.4790120 552s [43] 0.7997224 0.7643614 0.7997224 0.7643614 0.4790120 0.7488551 0.4790120 552s [50] 0.4790120 0.0000000 0.7488551 0.6580335 0.6580335 0.7488551 0.7997224 552s [57] 0.7488551 0.6580335 0.4790120 0.4790120 0.7997224 0.0000000 0.7488551 552s [64] 0.6580335 0.6580335 0.6580335 0.0000000 0.7488551 0.7997224 0.7643614 552s [71] 0.0000000 0.4790120 0.4790120 0.6580335 0.7997224 0.7997224 0.7643614 552s [78] 0.0000000 0.7643614 0.6580335 0.6580335 0.7997224 0.7997224 0.7997224 552s [85] 0.7997224 0.7488551 0.6580335 0.4790120 0.0000000 0.4790120 0.7488551 552s [92] 0.6580335 0.7997224 0.7488551 0.7643614 0.6580335 0.7643614 0.6580335 552s [99] 0.6580335 0.6580335 0.7997224 0.7643614 0.6580335 0.0000000 0.7643614 552s [106] 0.6580335 0.0000000 0.6580335 0.7997224 0.7997224 0.4790120 0.6580335 552s [113] 0.7643614 0.7997224 0.1680259 0.7643614 0.7643614 0.0000000 0.6580335 552s [120] 0.0000000 0.0000000 0.6580335 0.1680259 0.4790120 0.0000000 0.7643614 552s [127] 0.6580335 0.7997224 0.7643614 0.4790120 0.6580335 0.4790120 0.7488551 552s [134] 0.6580335 0.7997224 0.7643614 0.6580335 0.7488551 0.6580335 0.1680259 552s [141] 0.6580335 0.6580335 0.4790120 0.6580335 0.7643614 0.7488551 0.6580335 552s [148] 0.7997224 0.7997224 0.0000000 0.7643614 0.7997224 0.0000000 0.7997224 552s [155] 0.6580335 0.7488551 0.6580335 0.0000000 0.0000000 0.4790120 0.7997224 552s [162] 0.0000000 0.1680259 0.7997224 0.7997224 0.7643614 0.0000000 0.4790120 552s [169] 0.0000000 0.7997224 0.7997224 0.7643614 0.7643614 0.0000000 0.7488551 552s [176] 0.4790120 0.0000000 0.7643614 0.0000000 0.7488551 0.0000000 0.7997224 552s [183] 0.7643614 0.7643614 0.7997224 0.7997224 0.1680259 0.7488551 0.7997224 552s [190] 0.4790120 0.7488551 0.7488551 0.4790120 0.0000000 0.7488551 0.7997224 552s [197] 0.7488551 0.7488551 0.1680259 0.7997224 0.0000000 0.7488551 0.7997224 552s [204] 0.6580335 0.6580335 0.7488551 0.6580335 0.7488551 0.4790120 0.7643614 552s [211] 0.7997224 0.7997224 0.7997224 0.0000000 0.0000000 0.7643614 0.7643614 552s [218] 0.7997224 0.7997224 0.1680259 0.7488551 0.7488551 0.0000000 0.4790120 552s [225] 0.7488551 0.4790120 0.7997224 0.4790120 0.0000000 0.7488551 0.7997224 552s [232] 0.6580335 0.6580335 0.7997224 0.4790120 0.7643614 0.4790120 0.0000000 552s [239] 0.0000000 0.6580335 0.7488551 0.6580335 0.7643614 0.7997224 0.7488551 552s [246] 0.6580335 0.7997224 0.7488551 0.4790120 0.4790120 0.7488551 0.7643614 552s [253] 0.1680259 0.7488551 0.6580335 0.6580335 0.7488551 0.6580335 0.7643614 552s [260] 0.6580335 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.4790120 552s [267] 0.6580335 0.7997224 0.7997224 0.4790120 0.7997224 0.4790120 0.0000000 552s [274] 0.7997224 0.4790120 0.4790120 0.1680259 0.7643614 0.7643614 0.4790120 552s [281] 0.0000000 0.0000000 0.0000000 0.7643614 0.0000000 0.7997224 0.7997224 552s [288] 0.0000000 0.4790120 0.7643614 0.0000000 0.7643614 0.7488551 0.4790120 552s [295] 0.7488551 0.6580335 0.4790120 0.1680259 0.7488551 0.7488551 0.0000000 552s [302] 0.7643614 0.6580335 0.7488551 0.0000000 0.7643614 0.7643614 0.6580335 552s [309] 0.0000000 0.4790120 0.7643614 0.6580335 0.6580335 0.7997224 0.4790120 552s [316] 0.6580335 0.7997224 0.7488551 0.7643614 0.4790120 0.7997224 0.4790120 552s [323] 0.7488551 0.7643614 0.7643614 0.7488551 0.7997224 0.7643614 0.6580335 552s [330] 0.4790120 0.4790120 0.6580335 0.6580335 0.7488551 0.4790120 0.7997224 552s [337] 0.7997224 0.7643614 0.7643614 0.0000000 0.7997224 0.6580335 0.4790120 552s [344] 0.7997224 0.7643614 0.7488551 0.7997224 0.7997224 0.1680259 0.7643614 552s [351] 0.7488551 0.7488551 0.7997224 0.7643614 0.7997224 0.7643614 0.7997224 552s [358] 0.7643614 0.7997224 0.7488551 0.4790120 0.7997224 0.6580335 0.4790120 552s [365] 0.7997224 0.1680259 0.6580335 0.7997224 0.6580335 0.7488551 0.7997224 552s [372] 0.6580335 0.6580335 0.7997224 0.0000000 0.4790120 0.4790120 0.6580335 552s [379] 0.0000000 0.7488551 0.4790120 0.4790120 0.7643614 0.7997224 0.4790120 552s [386] 0.7488551 0.7997224 0.7488551 0.6580335 0.7997224 0.7997224 0.6580335 552s [393] 0.7643614 0.7997224 0.6580335 0.0000000 0.6580335 0.4790120 0.0000000 552s [400] 0.7997224 0.6580335 0.4790120 0.7643614 0.7643614 0.1680259 0.7643614 552s [407] 0.4790120 0.7997224 0.4790120 0.7997224 0.7997224 0.6580335 0.4790120 552s [414] 0.6580335 0.7488551 0.0000000 0.6580335 0.4790120 0.0000000 0.7488551 552s [421] 0.6580335 0.7997224 0.7997224 0.6580335 0.6580335 0.7643614 0.7643614 552s [428] 0.7643614 0.7488551 0.1680259 0.7488551 0.6580335 0.0000000 0.7997224 552s [435] 0.7488551 0.6580335 0.6580335 0.4790120 0.0000000 0.7997224 0.7488551 552s [442] 0.6580335 0.7643614 0.7997224 0.7643614 0.7488551 0.7643614 0.7488551 552s [449] 0.0000000 0.7488551 0.7488551 0.4790120 0.7643614 0.6580335 0.0000000 552s [456] 0.4790120 0.7643614 0.1680259 0.7997224 0.7488551 0.7488551 0.7643614 552s [463] 0.7643614 0.7997224 0.1680259 0.7488551 0.6580335 0.4790120 0.0000000 552s [470] 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.7488551 0.4790120 552s [477] 0.7997224 0.7488551 0.7488551 0.1680259 0.7997224 0.7488551 0.7488551 552s [484] 0.7997224 0.6580335 0.0000000 0.7488551 0.7643614 0.4790120 0.7997224 552s [491] 0.7488551 0.7488551 0.7643614 0.7997224 0.7488551 0.7643614 0.0000000 552s [498] 0.4790120 0.7643614 0.6580335 0.7997224 0.7643614 0.0000000 0.7488551 552s [505] 0.7997224 0.0000000 0.4790120 0.7488551 0.6580335 0.6580335 0.7997224 552s [512] 0.6580335 0.1680259 0.0000000 0.7997224 0.7997224 0.7997224 0.6580335 552s [519] 0.6580335 0.0000000 0.6580335 0.6580335 0.7997224 0.7488551 0.7997224 552s [526] 0.4790120 0.4790120 0.7488551 0.7643614 0.7643614 0.7997224 0.6580335 552s [533] 0.7488551 0.7643614 0.6580335 0.7997224 0.7997224 0.7997224 0.7488551 552s [540] 0.0000000 0.0000000 0.6580335 0.7997224 0.1680259 0.0000000 0.7643614 552s [547] 0.7488551 0.7643614 0.7643614 0.7488551 0.7643614 0.7643614 0.6580335 552s [554] 0.0000000 0.0000000 0.7997224 0.7643614 0.7488551 0.7488551 0.7997224 552s [561] 0.7997224 0.6580335 0.7488551 0.6580335 0.6580335 0.0000000 0.6580335 552s [568] 0.7997224 0.7488551 0.4790120 0.0000000 0.7997224 0.4790120 0.6580335 552s [575] 0.7488551 0.7997224 0.7643614 0.4790120 0.6580335 0.7997224 0.0000000 552s [582] 0.7488551 0.6580335 0.4790120 0.7643614 0.7997224 0.6580335 0.4790120 552s [589] 0.7643614 552s 552s $fit 552s [1] 16.85434 17.60229 18.01923 16.85434 13.94088 17.60229 18.01923 13.94088 552s [9] 16.85434 10.79647 16.85434 16.85434 18.01923 13.94088 11.64049 10.79647 552s [17] 16.85434 13.94088 13.94088 10.79647 18.01923 10.79647 18.01923 17.60229 552s [25] 17.60229 13.94088 17.60229 17.60229 13.94088 16.85434 18.01923 17.60229 552s [33] 13.94088 13.94088 13.94088 10.79647 10.79647 13.94088 17.60229 13.94088 552s [41] 13.94088 11.64049 13.94088 16.85434 13.94088 16.85434 11.64049 18.01923 552s [49] 11.64049 11.64049 10.79647 18.01923 17.60229 17.60229 18.01923 13.94088 552s [57] 18.01923 17.60229 11.64049 11.64049 13.94088 10.79647 18.01923 17.60229 552s [65] 17.60229 17.60229 10.79647 18.01923 13.94088 16.85434 10.79647 11.64049 552s [73] 11.64049 17.60229 13.94088 13.94088 16.85434 10.79647 16.85434 17.60229 552s [81] 17.60229 13.94088 13.94088 13.94088 13.94088 18.01923 17.60229 11.64049 552s [89] 10.79647 11.64049 18.01923 17.60229 13.94088 18.01923 16.85434 17.60229 552s [97] 16.85434 17.60229 17.60229 17.60229 13.94088 16.85434 17.60229 10.79647 552s [105] 16.85434 17.60229 10.79647 17.60229 13.94088 13.94088 11.64049 17.60229 552s [113] 16.85434 13.94088 10.96962 16.85434 16.85434 10.79647 17.60229 10.79647 552s [121] 10.79647 17.60229 10.96962 11.64049 10.79647 16.85434 17.60229 13.94088 552s [129] 16.85434 11.64049 17.60229 11.64049 18.01923 17.60229 13.94088 16.85434 552s [137] 17.60229 18.01923 17.60229 10.96962 17.60229 17.60229 11.64049 17.60229 552s [145] 16.85434 18.01923 17.60229 13.94088 13.94088 10.79647 16.85434 13.94088 552s [153] 10.79647 13.94088 17.60229 18.01923 17.60229 10.79647 10.79647 11.64049 552s [161] 13.94088 10.79647 10.96962 13.94088 13.94088 16.85434 10.79647 11.64049 552s [169] 10.79647 13.94088 13.94088 16.85434 16.85434 10.79647 18.01923 11.64049 552s [177] 10.79647 16.85434 10.79647 18.01923 10.79647 13.94088 16.85434 16.85434 552s [185] 13.94088 13.94088 10.96962 18.01923 13.94088 11.64049 18.01923 18.01923 552s [193] 11.64049 10.79647 18.01923 13.94088 18.01923 18.01923 10.96962 13.94088 552s [201] 10.79647 18.01923 13.94088 17.60229 17.60229 18.01923 17.60229 18.01923 552s [209] 11.64049 16.85434 13.94088 13.94088 13.94088 10.79647 10.79647 16.85434 552s [217] 16.85434 13.94088 13.94088 10.96962 18.01923 18.01923 10.79647 11.64049 552s [225] 18.01923 11.64049 13.94088 11.64049 10.79647 18.01923 13.94088 17.60229 552s [233] 17.60229 13.94088 11.64049 16.85434 11.64049 10.79647 10.79647 17.60229 552s [241] 18.01923 17.60229 16.85434 13.94088 18.01923 17.60229 13.94088 18.01923 552s [249] 11.64049 11.64049 18.01923 16.85434 10.96962 18.01923 17.60229 17.60229 552s [257] 18.01923 17.60229 16.85434 17.60229 11.64049 17.60229 17.60229 18.01923 552s [265] 16.85434 11.64049 17.60229 13.94088 13.94088 11.64049 13.94088 11.64049 552s [273] 10.79647 13.94088 11.64049 11.64049 10.96962 16.85434 16.85434 11.64049 552s [281] 10.79647 10.79647 10.79647 16.85434 10.79647 13.94088 13.94088 10.79647 552s [289] 11.64049 16.85434 10.79647 16.85434 18.01923 11.64049 18.01923 17.60229 552s [297] 11.64049 10.96962 18.01923 18.01923 10.79647 16.85434 17.60229 18.01923 552s [305] 10.79647 16.85434 16.85434 17.60229 10.79647 11.64049 16.85434 17.60229 552s [313] 17.60229 13.94088 11.64049 17.60229 13.94088 18.01923 16.85434 11.64049 552s [321] 13.94088 11.64049 18.01923 16.85434 16.85434 18.01923 13.94088 16.85434 552s [329] 17.60229 11.64049 11.64049 17.60229 17.60229 18.01923 11.64049 13.94088 552s [337] 13.94088 16.85434 16.85434 10.79647 13.94088 17.60229 11.64049 13.94088 552s [345] 16.85434 18.01923 13.94088 13.94088 10.96962 16.85434 18.01923 18.01923 552s [353] 13.94088 16.85434 13.94088 16.85434 13.94088 16.85434 13.94088 18.01923 552s [361] 11.64049 13.94088 17.60229 11.64049 13.94088 10.96962 17.60229 13.94088 552s [369] 17.60229 18.01923 13.94088 17.60229 17.60229 13.94088 10.79647 11.64049 552s [377] 11.64049 17.60229 10.79647 18.01923 11.64049 11.64049 16.85434 13.94088 552s [385] 11.64049 18.01923 13.94088 18.01923 17.60229 13.94088 13.94088 17.60229 552s [393] 16.85434 13.94088 17.60229 10.79647 17.60229 11.64049 10.79647 13.94088 552s [401] 17.60229 11.64049 16.85434 16.85434 10.96962 16.85434 11.64049 13.94088 552s [409] 11.64049 13.94088 13.94088 17.60229 11.64049 17.60229 18.01923 10.79647 552s [417] 17.60229 11.64049 10.79647 18.01923 17.60229 13.94088 13.94088 17.60229 552s [425] 17.60229 16.85434 16.85434 16.85434 18.01923 10.96962 18.01923 17.60229 552s [433] 10.79647 13.94088 18.01923 17.60229 17.60229 11.64049 10.79647 13.94088 552s [441] 18.01923 17.60229 16.85434 13.94088 16.85434 18.01923 16.85434 18.01923 552s [449] 10.79647 18.01923 18.01923 11.64049 16.85434 17.60229 10.79647 11.64049 552s [457] 16.85434 10.96962 13.94088 18.01923 18.01923 16.85434 16.85434 13.94088 552s [465] 10.96962 18.01923 17.60229 11.64049 10.79647 11.64049 17.60229 17.60229 552s [473] 18.01923 16.85434 18.01923 11.64049 13.94088 18.01923 18.01923 10.96962 552s [481] 13.94088 18.01923 18.01923 13.94088 17.60229 10.79647 18.01923 16.85434 552s [489] 11.64049 13.94088 18.01923 18.01923 16.85434 13.94088 18.01923 16.85434 552s [497] 10.79647 11.64049 16.85434 17.60229 13.94088 16.85434 10.79647 18.01923 552s [505] 13.94088 10.79647 11.64049 18.01923 17.60229 17.60229 13.94088 17.60229 552s [513] 10.96962 10.79647 13.94088 13.94088 13.94088 17.60229 17.60229 10.79647 552s [521] 17.60229 17.60229 13.94088 18.01923 13.94088 11.64049 11.64049 18.01923 552s [529] 16.85434 16.85434 13.94088 17.60229 18.01923 16.85434 17.60229 13.94088 552s [537] 13.94088 13.94088 18.01923 10.79647 10.79647 17.60229 13.94088 10.96962 552s [545] 10.79647 16.85434 18.01923 16.85434 16.85434 18.01923 16.85434 16.85434 552s [553] 17.60229 10.79647 10.79647 13.94088 16.85434 18.01923 18.01923 13.94088 552s [561] 13.94088 17.60229 18.01923 17.60229 17.60229 10.79647 17.60229 13.94088 552s [569] 18.01923 11.64049 10.79647 13.94088 11.64049 17.60229 18.01923 13.94088 552s [577] 16.85434 11.64049 17.60229 13.94088 10.79647 18.01923 17.60229 11.64049 552s [585] 16.85434 13.94088 17.60229 11.64049 16.85434 552s 552s $se.fit 552s [1] 0.4716508 0.3621952 0.5408090 0.4716508 0.4610877 0.3621952 0.5408090 552s [8] 0.4610877 0.4716508 0.5653200 0.4716508 0.4716508 0.5408090 0.4610877 552s [15] 0.3763389 0.5653200 0.4716508 0.4610877 0.4610877 0.5653200 0.5408090 552s [22] 0.5653200 0.5408090 0.3621952 0.3621952 0.4610877 0.3621952 0.3621952 552s [29] 0.4610877 0.4716508 0.5408090 0.3621952 0.4610877 0.4610877 0.4610877 552s [36] 0.5653200 0.5653200 0.4610877 0.3621952 0.4610877 0.4610877 0.3763389 552s [43] 0.4610877 0.4716508 0.4610877 0.4716508 0.3763389 0.5408090 0.3763389 552s [50] 0.3763389 0.5653200 0.5408090 0.3621952 0.3621952 0.5408090 0.4610877 552s [57] 0.5408090 0.3621952 0.3763389 0.3763389 0.4610877 0.5653200 0.5408090 552s [64] 0.3621952 0.3621952 0.3621952 0.5653200 0.5408090 0.4610877 0.4716508 552s [71] 0.5653200 0.3763389 0.3763389 0.3621952 0.4610877 0.4610877 0.4716508 552s [78] 0.5653200 0.4716508 0.3621952 0.3621952 0.4610877 0.4610877 0.4610877 552s [85] 0.4610877 0.5408090 0.3621952 0.3763389 0.5653200 0.3763389 0.5408090 552s [92] 0.3621952 0.4610877 0.5408090 0.4716508 0.3621952 0.4716508 0.3621952 552s [99] 0.3621952 0.3621952 0.4610877 0.4716508 0.3621952 0.5653200 0.4716508 552s [106] 0.3621952 0.5653200 0.3621952 0.4610877 0.4610877 0.3763389 0.3621952 552s [113] 0.4716508 0.4610877 0.4616804 0.4716508 0.4716508 0.5653200 0.3621952 552s [120] 0.5653200 0.5653200 0.3621952 0.4616804 0.3763389 0.5653200 0.4716508 552s [127] 0.3621952 0.4610877 0.4716508 0.3763389 0.3621952 0.3763389 0.5408090 552s [134] 0.3621952 0.4610877 0.4716508 0.3621952 0.5408090 0.3621952 0.4616804 552s [141] 0.3621952 0.3621952 0.3763389 0.3621952 0.4716508 0.5408090 0.3621952 552s [148] 0.4610877 0.4610877 0.5653200 0.4716508 0.4610877 0.5653200 0.4610877 552s [155] 0.3621952 0.5408090 0.3621952 0.5653200 0.5653200 0.3763389 0.4610877 552s [162] 0.5653200 0.4616804 0.4610877 0.4610877 0.4716508 0.5653200 0.3763389 552s [169] 0.5653200 0.4610877 0.4610877 0.4716508 0.4716508 0.5653200 0.5408090 552s [176] 0.3763389 0.5653200 0.4716508 0.5653200 0.5408090 0.5653200 0.4610877 552s [183] 0.4716508 0.4716508 0.4610877 0.4610877 0.4616804 0.5408090 0.4610877 552s [190] 0.3763389 0.5408090 0.5408090 0.3763389 0.5653200 0.5408090 0.4610877 552s [197] 0.5408090 0.5408090 0.4616804 0.4610877 0.5653200 0.5408090 0.4610877 552s [204] 0.3621952 0.3621952 0.5408090 0.3621952 0.5408090 0.3763389 0.4716508 552s [211] 0.4610877 0.4610877 0.4610877 0.5653200 0.5653200 0.4716508 0.4716508 552s [218] 0.4610877 0.4610877 0.4616804 0.5408090 0.5408090 0.5653200 0.3763389 552s [225] 0.5408090 0.3763389 0.4610877 0.3763389 0.5653200 0.5408090 0.4610877 552s [232] 0.3621952 0.3621952 0.4610877 0.3763389 0.4716508 0.3763389 0.5653200 552s [239] 0.5653200 0.3621952 0.5408090 0.3621952 0.4716508 0.4610877 0.5408090 552s [246] 0.3621952 0.4610877 0.5408090 0.3763389 0.3763389 0.5408090 0.4716508 552s [253] 0.4616804 0.5408090 0.3621952 0.3621952 0.5408090 0.3621952 0.4716508 552s [260] 0.3621952 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.3763389 552s [267] 0.3621952 0.4610877 0.4610877 0.3763389 0.4610877 0.3763389 0.5653200 552s [274] 0.4610877 0.3763389 0.3763389 0.4616804 0.4716508 0.4716508 0.3763389 552s [281] 0.5653200 0.5653200 0.5653200 0.4716508 0.5653200 0.4610877 0.4610877 552s [288] 0.5653200 0.3763389 0.4716508 0.5653200 0.4716508 0.5408090 0.3763389 552s [295] 0.5408090 0.3621952 0.3763389 0.4616804 0.5408090 0.5408090 0.5653200 552s [302] 0.4716508 0.3621952 0.5408090 0.5653200 0.4716508 0.4716508 0.3621952 552s [309] 0.5653200 0.3763389 0.4716508 0.3621952 0.3621952 0.4610877 0.3763389 552s [316] 0.3621952 0.4610877 0.5408090 0.4716508 0.3763389 0.4610877 0.3763389 552s [323] 0.5408090 0.4716508 0.4716508 0.5408090 0.4610877 0.4716508 0.3621952 552s [330] 0.3763389 0.3763389 0.3621952 0.3621952 0.5408090 0.3763389 0.4610877 552s [337] 0.4610877 0.4716508 0.4716508 0.5653200 0.4610877 0.3621952 0.3763389 552s [344] 0.4610877 0.4716508 0.5408090 0.4610877 0.4610877 0.4616804 0.4716508 552s [351] 0.5408090 0.5408090 0.4610877 0.4716508 0.4610877 0.4716508 0.4610877 552s [358] 0.4716508 0.4610877 0.5408090 0.3763389 0.4610877 0.3621952 0.3763389 552s [365] 0.4610877 0.4616804 0.3621952 0.4610877 0.3621952 0.5408090 0.4610877 552s [372] 0.3621952 0.3621952 0.4610877 0.5653200 0.3763389 0.3763389 0.3621952 552s [379] 0.5653200 0.5408090 0.3763389 0.3763389 0.4716508 0.4610877 0.3763389 552s [386] 0.5408090 0.4610877 0.5408090 0.3621952 0.4610877 0.4610877 0.3621952 552s [393] 0.4716508 0.4610877 0.3621952 0.5653200 0.3621952 0.3763389 0.5653200 552s [400] 0.4610877 0.3621952 0.3763389 0.4716508 0.4716508 0.4616804 0.4716508 552s [407] 0.3763389 0.4610877 0.3763389 0.4610877 0.4610877 0.3621952 0.3763389 552s [414] 0.3621952 0.5408090 0.5653200 0.3621952 0.3763389 0.5653200 0.5408090 552s [421] 0.3621952 0.4610877 0.4610877 0.3621952 0.3621952 0.4716508 0.4716508 552s [428] 0.4716508 0.5408090 0.4616804 0.5408090 0.3621952 0.5653200 0.4610877 552s [435] 0.5408090 0.3621952 0.3621952 0.3763389 0.5653200 0.4610877 0.5408090 552s [442] 0.3621952 0.4716508 0.4610877 0.4716508 0.5408090 0.4716508 0.5408090 552s [449] 0.5653200 0.5408090 0.5408090 0.3763389 0.4716508 0.3621952 0.5653200 552s [456] 0.3763389 0.4716508 0.4616804 0.4610877 0.5408090 0.5408090 0.4716508 552s [463] 0.4716508 0.4610877 0.4616804 0.5408090 0.3621952 0.3763389 0.5653200 552s [470] 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.5408090 0.3763389 552s [477] 0.4610877 0.5408090 0.5408090 0.4616804 0.4610877 0.5408090 0.5408090 552s [484] 0.4610877 0.3621952 0.5653200 0.5408090 0.4716508 0.3763389 0.4610877 552s [491] 0.5408090 0.5408090 0.4716508 0.4610877 0.5408090 0.4716508 0.5653200 552s [498] 0.3763389 0.4716508 0.3621952 0.4610877 0.4716508 0.5653200 0.5408090 552s [505] 0.4610877 0.5653200 0.3763389 0.5408090 0.3621952 0.3621952 0.4610877 552s [512] 0.3621952 0.4616804 0.5653200 0.4610877 0.4610877 0.4610877 0.3621952 552s [519] 0.3621952 0.5653200 0.3621952 0.3621952 0.4610877 0.5408090 0.4610877 552s [526] 0.3763389 0.3763389 0.5408090 0.4716508 0.4716508 0.4610877 0.3621952 552s [533] 0.5408090 0.4716508 0.3621952 0.4610877 0.4610877 0.4610877 0.5408090 552s [540] 0.5653200 0.5653200 0.3621952 0.4610877 0.4616804 0.5653200 0.4716508 552s [547] 0.5408090 0.4716508 0.4716508 0.5408090 0.4716508 0.4716508 0.3621952 552s [554] 0.5653200 0.5653200 0.4610877 0.4716508 0.5408090 0.5408090 0.4610877 552s [561] 0.4610877 0.3621952 0.5408090 0.3621952 0.3621952 0.5653200 0.3621952 552s [568] 0.4610877 0.5408090 0.3763389 0.5653200 0.4610877 0.3763389 0.3621952 552s [575] 0.5408090 0.4610877 0.4716508 0.3763389 0.3621952 0.4610877 0.5653200 552s [582] 0.5408090 0.3621952 0.3763389 0.4716508 0.4610877 0.3621952 0.3763389 552s [589] 0.4716508 552s 552s [1] 64.48518 552s [1] 3722.867 552s [1] 3722.867 552s Dose Response Model 552s 552s Model: betaMod 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -23.081 -4.023 0.069 3.767 16.317 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 1.02e+01 0.82024 552s eMax 7.36e+00 0.69530 552s delta1 2.25e+00 0.60058 552s delta2 1.01e+00 0.33271 552s age 5.72e-04 0.00829 552s centergreen 7.41e-01 0.73739 552s centerred 8.30e-01 0.74509 552s centersilver 7.30e-01 0.70097 552s centeryellow 6.56e-01 0.73274 552s 552s Residual standard error: 5.65 552s Degrees of freedom: 580 552s 552s Formula: y ~ cbind(XX, betaMod(x, 0, 1, delta1, delta2, scl)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s delta1 2.253e+00 6.006e-01 3.751 0.000194 *** 552s delta2 1.006e+00 3.327e-01 3.025 0.002600 ** 552s .lin.(Intercept) 1.023e+01 8.202e-01 12.470 < 2e-16 *** 552s .lin.centergreen 7.409e-01 7.374e-01 1.005 0.315410 552s .lin.centerred 8.298e-01 7.451e-01 1.114 0.265866 552s .lin.centersilver 7.301e-01 7.010e-01 1.042 0.298051 552s .lin.centeryellow 6.562e-01 7.327e-01 0.896 0.370886 552s .lin.age 5.723e-04 8.288e-03 0.069 0.944970 552s .lin7 7.357e+00 6.953e-01 10.581 < 2e-16 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 5.653 on 580 degrees of freedom 552s 552s Number of iterations to convergence: 6 552s Achieved convergence tolerance: 9.472e-06 552s 552s e0 eMax delta1 delta2 552s e0 0.672788559 -0.2729452045 2.029556e-01 8.893435e-02 552s eMax -0.272945205 0.4834404097 -4.411253e-02 1.212204e-02 552s delta1 0.202955599 -0.0441125324 3.606932e-01 1.869163e-01 552s delta2 0.088934351 0.0121220363 1.869163e-01 1.106931e-01 552s age -0.003530727 0.0001030079 4.984077e-05 7.767012e-05 552s centergreen -0.234450341 -0.0348602442 1.207912e-02 1.405608e-03 552s centerred -0.253662861 -0.0121021695 6.628056e-04 -2.474390e-03 552s centersilver -0.222055302 -0.0379891037 1.347032e-02 4.810797e-03 552s centeryellow -0.242096858 -0.0036488341 1.244170e-02 2.099443e-03 552s age centergreen centerred centersilver 552s e0 -3.530727e-03 -0.2344503414 -0.2536628613 -2.220553e-01 552s eMax 1.030079e-04 -0.0348602442 -0.0121021695 -3.798910e-02 552s delta1 4.984077e-05 0.0120791210 0.0006628056 1.347032e-02 552s delta2 7.767012e-05 0.0014056077 -0.0024743904 4.810797e-03 552s age 6.868689e-05 0.0001513555 0.0001912581 -2.484136e-05 552s centergreen 1.513555e-04 0.5437481113 0.2513884521 2.524566e-01 552s centerred 1.912581e-04 0.2513884521 0.5551521388 2.504165e-01 552s centersilver -2.484136e-05 0.2524565639 0.2504164883 4.913597e-01 552s centeryellow -1.767809e-05 0.2510775793 0.2504115028 2.500668e-01 552s centeryellow 552s e0 -2.420969e-01 552s eMax -3.648834e-03 552s delta1 1.244170e-02 552s delta2 2.099443e-03 552s age -1.767809e-05 552s centergreen 2.510776e-01 552s centerred 2.504115e-01 552s centersilver 2.500668e-01 552s centeryellow 5.369021e-01 552s delta1 delta2 .lin.(Intercept) .lin.centergreen 552s delta1 3.606961e-01 1.869176e-01 0.202956171 0.0120792615 552s delta2 1.869176e-01 1.106938e-01 0.088934648 0.0014056742 552s .lin.(Intercept) 2.029562e-01 8.893465e-02 0.672787602 -0.2344503743 552s .lin.centergreen 1.207926e-02 1.405674e-03 -0.234450374 0.5437481112 552s .lin.centerred 6.627065e-04 -2.474441e-03 -0.253662951 0.2513884457 552s .lin.centersilver 1.347037e-02 4.810825e-03 -0.222055391 0.2524565593 552s .lin.centeryellow 1.244156e-02 2.099363e-03 -0.242097015 0.2510775716 552s .lin.age 4.984142e-05 7.767047e-05 -0.003530726 0.0001513556 552s .lin7 -4.411231e-02 1.212224e-02 -0.272944309 -0.0348602205 552s .lin.centerred .lin.centersilver .lin.centeryellow 552s delta1 0.0006627065 1.347037e-02 1.244156e-02 552s delta2 -0.0024744413 4.810825e-03 2.099363e-03 552s .lin.(Intercept) -0.2536629506 -2.220554e-01 -2.420970e-01 552s .lin.centergreen 0.2513884457 2.524566e-01 2.510776e-01 552s .lin.centerred 0.5551521364 2.504165e-01 2.504115e-01 552s .lin.centersilver 0.2504164813 4.913597e-01 2.500668e-01 552s .lin.centeryellow 0.2504114958 2.500668e-01 5.369021e-01 552s .lin.age 0.0001912581 -2.484131e-05 -1.767806e-05 552s .lin7 -0.0121021533 -3.798904e-02 -3.648777e-03 552s .lin.age .lin7 552s delta1 4.984142e-05 -0.0441123055 552s delta2 7.767047e-05 0.0121222432 552s .lin.(Intercept) -3.530726e-03 -0.2729443093 552s .lin.centergreen 1.513556e-04 -0.0348602205 552s .lin.centerred 1.912581e-04 -0.0121021533 552s .lin.centersilver -2.484131e-05 -0.0379890373 552s .lin.centeryellow -1.767806e-05 -0.0036487770 552s .lin.age 6.868689e-05 0.0001030081 552s .lin7 1.030081e-04 0.4834404337 552s $fit 552s [1] 0.000000 2.289162 552s 552s $se.fit 552s [1] 0.0000000 0.7519464 552s 552s $fit 552s [1] 10.91275 13.20191 552s 552s $se.fit 552s [1] 0.7364602 0.6423551 552s 552s [1] 65.39866 552s [1] -485.5937 552s [1] -485.5937 552s Dose Response Model 552s 552s Model: emax 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -0.0666 -0.0180 -0.0011 0.0193 0.0692 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -0.5830 6.00e-03 552s eMax 0.0163 3.36e-02 552s ed50 286.5994 1.91e+03 552s 552s Residual standard error: 0.0281 552s Degrees of freedom: 111 552s 552s Formula: y ~ emax(x, e0, emax, ed50) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s e0 -0.58297 0.00600 -97.164 <2e-16 *** 552s emax 0.01632 0.03356 0.486 0.628 552s ed50 286.45918 1905.11276 0.150 0.881 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.02814 on 111 degrees of freedom 552s 552s Number of iterations to convergence: 8 552s Achieved convergence tolerance: 9.607e-06 552s 552s e0 eMax ed50 552s e0 3.599786e-05 -2.913476e-05 1.313843e+00 552s eMax -2.913476e-05 1.126946e-03 6.130311e+01 552s ed50 1.313843e+00 6.130311e+01 3.631673e+06 552s e0 emax ed50 552s e0 3.599786e-05 -2.914142e-05 1.313001e+00 552s emax -2.914142e-05 1.126323e-03 6.126673e+01 552s ed50 1.313001e+00 6.126673e+01 3.629455e+06 552s $fit 552s [1] 0.01155472 0.01155472 0.00000000 0.01155472 0.01155472 0.01155472 552s [7] 0.01056820 0.01056820 0.01056820 0.01155472 0.01239306 0.01056820 552s [13] 0.00000000 0.01239306 0.01155472 0.01056820 0.01056820 0.00000000 552s [19] 0.01155472 0.01212084 0.01212084 0.01056820 0.00000000 0.01155472 552s [25] 0.01056820 0.01056820 0.01155472 0.00000000 0.00000000 0.01155472 552s [31] 0.01056820 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 552s [37] 0.01155472 0.01212084 0.00000000 0.01155472 0.01239306 0.01155472 552s [43] 0.01056820 0.01056820 0.01155472 0.01155472 0.01155472 0.00000000 552s [49] 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 0.01239306 552s [55] 0.00000000 0.01056820 0.01155472 0.01056820 0.01239306 0.01239306 552s [61] 0.01056820 0.01239306 0.01056820 0.01155472 0.01212084 0.01155472 552s [67] 0.01056820 0.01056820 0.01239306 0.01056820 0.00000000 0.01155472 552s [73] 0.01239306 0.01155472 0.01155472 0.01056820 0.00000000 0.00000000 552s [79] 0.01155472 0.00000000 0.00000000 0.00000000 0.01155472 0.01155472 552s [85] 0.01056820 0.01056820 0.01155472 0.01056820 0.01155472 0.01155472 552s [91] 0.01212084 0.01155472 0.01212084 0.01056820 0.00000000 0.01155472 552s [97] 0.01155472 0.01056820 0.01155472 0.00000000 0.01155472 0.01155472 552s [103] 0.01056820 0.01056820 0.01056820 0.00000000 0.01155472 0.00000000 552s [109] 0.01056820 0.01056820 0.01155472 0.01056820 0.00000000 0.01056820 552s 552s $se.fit 552s [1] 0.006800657 0.006800657 0.000000000 0.006800657 0.006800657 0.006800657 552s [7] 0.007368990 0.007368990 0.007368990 0.006800657 0.008598392 0.007368990 552s [13] 0.000000000 0.008598392 0.006800657 0.007368990 0.007368990 0.000000000 552s [19] 0.006800657 0.007779856 0.007779856 0.007368990 0.000000000 0.006800657 552s [25] 0.007368990 0.007368990 0.006800657 0.000000000 0.000000000 0.006800657 552s [31] 0.007368990 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 552s [37] 0.006800657 0.007779856 0.000000000 0.006800657 0.008598392 0.006800657 552s [43] 0.007368990 0.007368990 0.006800657 0.006800657 0.006800657 0.000000000 552s [49] 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 0.008598392 552s [55] 0.000000000 0.007368990 0.006800657 0.007368990 0.008598392 0.008598392 552s [61] 0.007368990 0.008598392 0.007368990 0.006800657 0.007779856 0.006800657 552s [67] 0.007368990 0.007368990 0.008598392 0.007368990 0.000000000 0.006800657 552s [73] 0.008598392 0.006800657 0.006800657 0.007368990 0.000000000 0.000000000 552s [79] 0.006800657 0.000000000 0.000000000 0.000000000 0.006800657 0.006800657 552s [85] 0.007368990 0.007368990 0.006800657 0.007368990 0.006800657 0.006800657 552s [91] 0.007779856 0.006800657 0.007779856 0.007368990 0.000000000 0.006800657 552s [97] 0.006800657 0.007368990 0.006800657 0.000000000 0.006800657 0.006800657 552s [103] 0.007368990 0.007368990 0.007368990 0.000000000 0.006800657 0.000000000 552s [109] 0.007368990 0.007368990 0.006800657 0.007368990 0.000000000 0.007368990 552s 552s $fit 552s [1] -0.5714146 -0.5714146 -0.5829694 -0.5714146 -0.5714146 -0.5714146 552s [7] -0.5724012 -0.5724012 -0.5724012 -0.5714146 -0.5705763 -0.5724012 552s [13] -0.5829694 -0.5705763 -0.5714146 -0.5724012 -0.5724012 -0.5829694 552s [19] -0.5714146 -0.5708485 -0.5708485 -0.5724012 -0.5829694 -0.5714146 552s [25] -0.5724012 -0.5724012 -0.5714146 -0.5829694 -0.5829694 -0.5714146 552s [31] -0.5724012 -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 552s [37] -0.5714146 -0.5708485 -0.5829694 -0.5714146 -0.5705763 -0.5714146 552s [43] -0.5724012 -0.5724012 -0.5714146 -0.5714146 -0.5714146 -0.5829694 552s [49] -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 -0.5705763 552s [55] -0.5829694 -0.5724012 -0.5714146 -0.5724012 -0.5705763 -0.5705763 552s [61] -0.5724012 -0.5705763 -0.5724012 -0.5714146 -0.5708485 -0.5714146 552s [67] -0.5724012 -0.5724012 -0.5705763 -0.5724012 -0.5829694 -0.5714146 552s [73] -0.5705763 -0.5714146 -0.5714146 -0.5724012 -0.5829694 -0.5829694 552s [79] -0.5714146 -0.5829694 -0.5829694 -0.5829694 -0.5714146 -0.5714146 552s [85] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5714146 -0.5714146 552s [91] -0.5708485 -0.5714146 -0.5708485 -0.5724012 -0.5829694 -0.5714146 552s [97] -0.5714146 -0.5724012 -0.5714146 -0.5829694 -0.5714146 -0.5714146 552s [103] -0.5724012 -0.5724012 -0.5724012 -0.5829694 -0.5714146 -0.5829694 552s [109] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5829694 -0.5724012 552s 552s $se.fit 552s [1] 0.003169353 0.003169353 0.005999821 0.003169353 0.003169353 0.003169353 552s [7] 0.004290400 0.004290400 0.004290400 0.003169353 0.006190654 0.004290400 552s [13] 0.005999821 0.006190654 0.003169353 0.004290400 0.004290400 0.005999821 552s [19] 0.003169353 0.004963663 0.004963663 0.004290400 0.005999821 0.003169353 552s [25] 0.004290400 0.004290400 0.003169353 0.005999821 0.005999821 0.003169353 552s [31] 0.004290400 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 552s [37] 0.003169353 0.004963663 0.005999821 0.003169353 0.006190654 0.003169353 552s [43] 0.004290400 0.004290400 0.003169353 0.003169353 0.003169353 0.005999821 552s [49] 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 0.006190654 552s [55] 0.005999821 0.004290400 0.003169353 0.004290400 0.006190654 0.006190654 552s [61] 0.004290400 0.006190654 0.004290400 0.003169353 0.004963663 0.003169353 552s [67] 0.004290400 0.004290400 0.006190654 0.004290400 0.005999821 0.003169353 552s [73] 0.006190654 0.003169353 0.003169353 0.004290400 0.005999821 0.005999821 552s [79] 0.003169353 0.005999821 0.005999821 0.005999821 0.003169353 0.003169353 552s [85] 0.004290400 0.004290400 0.003169353 0.004290400 0.003169353 0.003169353 552s [91] 0.004963663 0.003169353 0.004963663 0.004290400 0.005999821 0.003169353 552s [97] 0.003169353 0.004290400 0.003169353 0.005999821 0.003169353 0.003169353 552s [103] 0.004290400 0.004290400 0.004290400 0.005999821 0.003169353 0.005999821 552s [109] 0.004290400 0.004290400 0.003169353 0.004290400 0.005999821 0.004290400 552s 552s [1] 126.5178 552s [1] -481.376 552s [1] -481.378 552s Dose Response Model 552s 552s Model: emax 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -0.07408 -0.01641 -0.00232 0.01807 0.07476 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -5.81e-01 8.97e-03 552s eMax 2.93e-02 9.13e-02 552s ed50 9.03e+02 5.00e+03 552s age -1.22e-04 1.06e-04 552s centergreen 1.07e-02 8.31e-03 552s centerred 9.27e-03 7.73e-03 552s centersilver 1.22e-03 8.91e-03 552s centeryellow -4.65e-03 8.50e-03 552s 552s Residual standard error: 0.0281 552s Degrees of freedom: 106 552s 552s Formula: y ~ cbind(XX, emax(x, 0, 1, ed50)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s ed50 1.111e+03 6.451e+03 0.172 0.864 552s .lin.(Intercept) -5.813e-01 8.970e-03 -64.810 <2e-16 *** 552s .lin.centergreen 1.071e-02 8.309e-03 1.288 0.200 552s .lin.centerred 9.301e-03 7.726e-03 1.204 0.231 552s .lin.centersilver 1.196e-03 8.915e-03 0.134 0.894 552s .lin.centeryellow -4.665e-03 8.497e-03 -0.549 0.584 552s .lin.age -1.213e-04 1.057e-04 -1.148 0.254 552s .lin7 3.300e-02 1.170e-01 0.282 0.778 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.02808 on 106 degrees of freedom 552s 552s Number of iterations to convergence: 9 552s Achieved convergence tolerance: 7.028e-06 552s 552s e0 eMax ed50 age 552s e0 8.046543e-05 -3.844545e-05 2.355425e+00 -4.980066e-07 552s eMax -3.844545e-05 8.342573e-03 4.493061e+02 1.107091e-06 552s ed50 2.355425e+00 4.493061e+02 2.497229e+07 6.444381e-02 552s age -4.980066e-07 1.107091e-06 6.444381e-02 1.116195e-08 552s centergreen -1.978501e-05 6.446464e-05 4.524614e+00 -8.645567e-08 552s centerred -3.432079e-05 7.922237e-05 3.670388e+00 1.157010e-08 552s centersilver -1.753629e-05 -7.656779e-05 -3.796015e+00 -2.309374e-07 552s centeryellow -3.332560e-05 -5.044361e-05 -2.141277e+00 1.346886e-07 552s centergreen centerred centersilver centeryellow 552s e0 -1.978501e-05 -3.432079e-05 -1.753629e-05 -3.332560e-05 552s eMax 6.446464e-05 7.922237e-05 -7.656779e-05 -5.044361e-05 552s ed50 4.524614e+00 3.670388e+00 -3.796015e+00 -2.141277e+00 552s age -8.645567e-08 1.157010e-08 -2.309374e-07 1.346886e-07 552s centergreen 6.902160e-05 3.007695e-05 3.223410e-05 2.943878e-05 552s centerred 3.007695e-05 5.968790e-05 2.924362e-05 2.945739e-05 552s centersilver 3.223410e-05 2.924362e-05 7.947639e-05 2.823145e-05 552s centeryellow 2.943878e-05 2.945739e-05 2.823145e-05 7.219729e-05 552s ed50 .lin.(Intercept) .lin.centergreen 552s ed50 4.162109e+07 3.618133e+00 6.072527e+00 552s .lin.(Intercept) 3.618133e+00 8.045192e-05 -1.978784e-05 552s .lin.centergreen 6.072527e+00 -1.978784e-05 6.904772e-05 552s .lin.centerred 4.627132e+00 -3.432899e-05 3.008663e-05 552s .lin.centersilver -4.847154e+00 -1.752828e-05 3.222029e-05 552s .lin.centeryellow -2.727240e+00 -3.332482e-05 2.942341e-05 552s .lin.age 8.505295e-02 -4.980346e-07 -8.605363e-08 552s .lin7 7.456212e+02 -2.614221e-05 9.001668e-05 552s .lin.centerred .lin.centersilver .lin.centeryellow 552s ed50 4.627132e+00 -4.847154e+00 -2.727240e+00 552s .lin.(Intercept) -3.432899e-05 -1.752828e-05 -3.332482e-05 552s .lin.centergreen 3.008663e-05 3.222029e-05 2.942341e-05 552s .lin.centerred 5.968601e-05 2.924192e-05 2.945040e-05 552s .lin.centersilver 2.924192e-05 7.947836e-05 2.823890e-05 552s .lin.centeryellow 2.945040e-05 2.823890e-05 7.220391e-05 552s .lin.age 1.172543e-08 -2.311322e-07 1.344697e-07 552s .lin7 9.802604e-05 -9.643580e-05 -6.245218e-05 552s .lin.age .lin7 552s ed50 8.505295e-02 7.456212e+02 552s .lin.(Intercept) -4.980346e-07 -2.614221e-05 552s .lin.centergreen -8.605363e-08 9.001668e-05 552s .lin.centerred 1.172543e-08 9.802604e-05 552s .lin.centersilver -2.311322e-07 -9.643580e-05 552s .lin.centeryellow 1.344697e-07 -6.245218e-05 552s .lin.age 1.116761e-08 1.469361e-06 552s .lin7 1.469361e-06 1.368628e-02 552s $fit 552s [1] 0.000000000 0.002916944 552s 552s $se.fit 552s [1] 0.000000 0.005795 552s 552s $fit 552s [1] -0.5861913 -0.5832744 552s 552s $se.fit 552s [1] 0.008937545 0.009550033 552s 552s [1] 186.1323 552s [1] 2049.321 552s [1] 2049.321 552s Dose Response Model 552s 552s Model: sigEmax 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -13.6383 -2.8339 0.0791 3.0983 10.5294 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -10.92 0.555 552s eMax 17.17 3.430 552s ed50 379.22 148.679 552s h 1.38 0.349 552s 552s Residual standard error: 4.37 552s Degrees of freedom: 349 552s 552s Formula: y ~ sigEmax(x, e0, emax, ed50, h) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s e0 -10.9166 0.5552 -19.664 < 2e-16 *** 552s emax 17.1659 3.4296 5.005 8.87e-07 *** 552s ed50 379.2177 148.6773 2.551 0.0112 * 552s h 1.3754 0.3490 3.941 9.81e-05 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 4.372 on 349 degrees of freedom 552s 552s Number of iterations to convergence: 4 552s Achieved convergence tolerance: 7.009e-07 552s 552s e0 eMax ed50 h 552s e0 0.30821303 -0.518459 6.111487 0.06026432 552s eMax -0.51845897 11.762554 468.796910 -1.10430575 552s ed50 6.11148678 468.796910 22105.398371 -40.29693110 552s h 0.06026432 -1.104306 -40.296931 0.12181039 552s e0 emax ed50 h 552s e0 0.30821303 -0.5184566 6.111568 0.06026447 552s emax -0.51845655 11.7623435 468.787156 -1.10429851 552s ed50 6.11156813 468.7871558 22104.941251 -40.29652562 552s h 0.06026447 -1.1042985 -40.296526 0.12181099 552s $fit 552s [1] 12.497935 12.497935 13.842361 2.869998 13.842361 13.842361 0.000000 552s [8] 0.000000 13.842361 2.869998 12.497935 12.497935 11.114421 12.497935 552s [15] 12.497935 12.497935 12.497935 12.497935 0.000000 12.497935 12.497935 552s [22] 0.000000 13.842361 13.842361 0.000000 0.000000 2.869998 12.497935 552s [29] 2.869998 2.869998 13.842361 0.000000 11.114421 12.497935 0.000000 552s [36] 13.842361 13.842361 12.497935 13.842361 2.869998 12.497935 12.497935 552s [43] 12.497935 2.869998 12.497935 12.497935 11.114421 12.497935 13.842361 552s [50] 13.842361 12.497935 0.000000 12.497935 12.497935 0.000000 12.497935 552s [57] 0.000000 13.842361 12.497935 2.869998 12.497935 13.842361 12.497935 552s [64] 13.842361 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 552s [71] 12.497935 2.869998 12.497935 12.497935 0.000000 13.842361 0.000000 552s [78] 13.842361 12.497935 12.497935 12.497935 12.497935 13.842361 2.869998 552s [85] 12.497935 12.497935 12.497935 0.000000 0.000000 0.000000 0.000000 552s [92] 2.869998 12.497935 12.497935 2.869998 12.497935 12.497935 2.869998 552s [99] 12.497935 0.000000 12.497935 0.000000 2.869998 2.869998 2.869998 552s [106] 12.497935 13.842361 12.497935 2.869998 0.000000 13.842361 2.869998 552s [113] 12.497935 0.000000 12.497935 0.000000 13.842361 12.497935 0.000000 552s [120] 12.497935 11.114421 13.842361 12.497935 12.497935 0.000000 12.497935 552s [127] 2.869998 13.842361 12.497935 13.842361 12.497935 2.869998 12.497935 552s [134] 12.497935 12.497935 12.497935 12.497935 13.842361 13.842361 0.000000 552s [141] 11.114421 12.497935 0.000000 12.497935 13.842361 12.497935 11.114421 552s [148] 12.497935 0.000000 0.000000 2.869998 13.842361 0.000000 2.869998 552s [155] 13.842361 2.869998 11.114421 11.114421 12.497935 0.000000 12.497935 552s [162] 12.497935 2.869998 2.869998 12.497935 12.497935 12.497935 12.497935 552s [169] 2.869998 11.114421 0.000000 13.842361 12.497935 11.114421 12.497935 552s [176] 13.842361 13.842361 12.497935 12.497935 12.497935 12.497935 12.497935 552s [183] 2.869998 13.842361 0.000000 12.497935 12.497935 12.497935 2.869998 552s [190] 13.842361 12.497935 13.842361 2.869998 13.842361 12.497935 12.497935 552s [197] 12.497935 0.000000 11.114421 2.869998 12.497935 2.869998 12.497935 552s [204] 0.000000 12.497935 13.842361 12.497935 13.842361 12.497935 2.869998 552s [211] 2.869998 12.497935 13.842361 13.842361 2.869998 0.000000 13.842361 552s [218] 12.497935 12.497935 0.000000 13.842361 12.497935 12.497935 0.000000 552s [225] 13.842361 11.114421 12.497935 2.869998 12.497935 0.000000 12.497935 552s [232] 12.497935 13.842361 0.000000 12.497935 12.497935 13.842361 0.000000 552s [239] 13.842361 13.842361 12.497935 13.842361 0.000000 2.869998 12.497935 552s [246] 13.842361 12.497935 12.497935 13.842361 2.869998 0.000000 0.000000 552s [253] 11.114421 2.869998 12.497935 2.869998 13.842361 0.000000 12.497935 552s [260] 12.497935 12.497935 12.497935 11.114421 0.000000 0.000000 0.000000 552s [267] 0.000000 0.000000 0.000000 12.497935 13.842361 13.842361 2.869998 552s [274] 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 13.842361 552s [281] 12.497935 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 552s [288] 11.114421 0.000000 12.497935 12.497935 0.000000 2.869998 12.497935 552s [295] 0.000000 0.000000 13.842361 0.000000 12.497935 13.842361 12.497935 552s [302] 12.497935 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 552s [309] 11.114421 2.869998 2.869998 0.000000 13.842361 0.000000 12.497935 552s [316] 2.869998 13.842361 0.000000 13.842361 11.114421 12.497935 0.000000 552s [323] 12.497935 12.497935 0.000000 13.842361 13.842361 13.842361 13.842361 552s [330] 11.114421 2.869998 0.000000 12.497935 0.000000 12.497935 13.842361 552s [337] 12.497935 12.497935 12.497935 12.497935 12.497935 13.842361 12.497935 552s [344] 2.869998 13.842361 13.842361 2.869998 11.114421 2.869998 12.497935 552s [351] 12.497935 12.497935 13.842361 552s 552s $se.fit 552s [1] 0.6365415 0.6365415 0.7457881 0.8126372 0.7457881 0.7457881 0.0000000 552s [8] 0.0000000 0.7457881 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 552s [15] 0.6365415 0.6365415 0.6365415 0.6365415 0.0000000 0.6365415 0.6365415 552s [22] 0.0000000 0.7457881 0.7457881 0.0000000 0.0000000 0.8126372 0.6365415 552s [29] 0.8126372 0.8126372 0.7457881 0.0000000 0.8003756 0.6365415 0.0000000 552s [36] 0.7457881 0.7457881 0.6365415 0.7457881 0.8126372 0.6365415 0.6365415 552s [43] 0.6365415 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 0.7457881 552s [50] 0.7457881 0.6365415 0.0000000 0.6365415 0.6365415 0.0000000 0.6365415 552s [57] 0.0000000 0.7457881 0.6365415 0.8126372 0.6365415 0.7457881 0.6365415 552s [64] 0.7457881 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 552s [71] 0.6365415 0.8126372 0.6365415 0.6365415 0.0000000 0.7457881 0.0000000 552s [78] 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.8126372 552s [85] 0.6365415 0.6365415 0.6365415 0.0000000 0.0000000 0.0000000 0.0000000 552s [92] 0.8126372 0.6365415 0.6365415 0.8126372 0.6365415 0.6365415 0.8126372 552s [99] 0.6365415 0.0000000 0.6365415 0.0000000 0.8126372 0.8126372 0.8126372 552s [106] 0.6365415 0.7457881 0.6365415 0.8126372 0.0000000 0.7457881 0.8126372 552s [113] 0.6365415 0.0000000 0.6365415 0.0000000 0.7457881 0.6365415 0.0000000 552s [120] 0.6365415 0.8003756 0.7457881 0.6365415 0.6365415 0.0000000 0.6365415 552s [127] 0.8126372 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 0.6365415 552s [134] 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.7457881 0.0000000 552s [141] 0.8003756 0.6365415 0.0000000 0.6365415 0.7457881 0.6365415 0.8003756 552s [148] 0.6365415 0.0000000 0.0000000 0.8126372 0.7457881 0.0000000 0.8126372 552s [155] 0.7457881 0.8126372 0.8003756 0.8003756 0.6365415 0.0000000 0.6365415 552s [162] 0.6365415 0.8126372 0.8126372 0.6365415 0.6365415 0.6365415 0.6365415 552s [169] 0.8126372 0.8003756 0.0000000 0.7457881 0.6365415 0.8003756 0.6365415 552s [176] 0.7457881 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 552s [183] 0.8126372 0.7457881 0.0000000 0.6365415 0.6365415 0.6365415 0.8126372 552s [190] 0.7457881 0.6365415 0.7457881 0.8126372 0.7457881 0.6365415 0.6365415 552s [197] 0.6365415 0.0000000 0.8003756 0.8126372 0.6365415 0.8126372 0.6365415 552s [204] 0.0000000 0.6365415 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 552s [211] 0.8126372 0.6365415 0.7457881 0.7457881 0.8126372 0.0000000 0.7457881 552s [218] 0.6365415 0.6365415 0.0000000 0.7457881 0.6365415 0.6365415 0.0000000 552s [225] 0.7457881 0.8003756 0.6365415 0.8126372 0.6365415 0.0000000 0.6365415 552s [232] 0.6365415 0.7457881 0.0000000 0.6365415 0.6365415 0.7457881 0.0000000 552s [239] 0.7457881 0.7457881 0.6365415 0.7457881 0.0000000 0.8126372 0.6365415 552s [246] 0.7457881 0.6365415 0.6365415 0.7457881 0.8126372 0.0000000 0.0000000 552s [253] 0.8003756 0.8126372 0.6365415 0.8126372 0.7457881 0.0000000 0.6365415 552s [260] 0.6365415 0.6365415 0.6365415 0.8003756 0.0000000 0.0000000 0.0000000 552s [267] 0.0000000 0.0000000 0.0000000 0.6365415 0.7457881 0.7457881 0.8126372 552s [274] 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 0.7457881 552s [281] 0.6365415 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 552s [288] 0.8003756 0.0000000 0.6365415 0.6365415 0.0000000 0.8126372 0.6365415 552s [295] 0.0000000 0.0000000 0.7457881 0.0000000 0.6365415 0.7457881 0.6365415 552s [302] 0.6365415 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 552s [309] 0.8003756 0.8126372 0.8126372 0.0000000 0.7457881 0.0000000 0.6365415 552s [316] 0.8126372 0.7457881 0.0000000 0.7457881 0.8003756 0.6365415 0.0000000 552s [323] 0.6365415 0.6365415 0.0000000 0.7457881 0.7457881 0.7457881 0.7457881 552s [330] 0.8003756 0.8126372 0.0000000 0.6365415 0.0000000 0.6365415 0.7457881 552s [337] 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.6365415 552s [344] 0.8126372 0.7457881 0.7457881 0.8126372 0.8003756 0.8126372 0.6365415 552s [351] 0.6365415 0.6365415 0.7457881 552s 552s $fit 552s [1] 1.5813420 1.5813420 2.9257678 -8.0465951 2.9257678 2.9257678 552s [7] -10.9165933 -10.9165933 2.9257678 -8.0465951 1.5813420 1.5813420 552s [13] 0.1978278 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 552s [19] -10.9165933 1.5813420 1.5813420 -10.9165933 2.9257678 2.9257678 552s [25] -10.9165933 -10.9165933 -8.0465951 1.5813420 -8.0465951 -8.0465951 552s [31] 2.9257678 -10.9165933 0.1978278 1.5813420 -10.9165933 2.9257678 552s [37] 2.9257678 1.5813420 2.9257678 -8.0465951 1.5813420 1.5813420 552s [43] 1.5813420 -8.0465951 1.5813420 1.5813420 0.1978278 1.5813420 552s [49] 2.9257678 2.9257678 1.5813420 -10.9165933 1.5813420 1.5813420 552s [55] -10.9165933 1.5813420 -10.9165933 2.9257678 1.5813420 -8.0465951 552s [61] 1.5813420 2.9257678 1.5813420 2.9257678 2.9257678 1.5813420 552s [67] 1.5813420 -8.0465951 1.5813420 -8.0465951 1.5813420 -8.0465951 552s [73] 1.5813420 1.5813420 -10.9165933 2.9257678 -10.9165933 2.9257678 552s [79] 1.5813420 1.5813420 1.5813420 1.5813420 2.9257678 -8.0465951 552s [85] 1.5813420 1.5813420 1.5813420 -10.9165933 -10.9165933 -10.9165933 552s [91] -10.9165933 -8.0465951 1.5813420 1.5813420 -8.0465951 1.5813420 552s [97] 1.5813420 -8.0465951 1.5813420 -10.9165933 1.5813420 -10.9165933 552s [103] -8.0465951 -8.0465951 -8.0465951 1.5813420 2.9257678 1.5813420 552s [109] -8.0465951 -10.9165933 2.9257678 -8.0465951 1.5813420 -10.9165933 552s [115] 1.5813420 -10.9165933 2.9257678 1.5813420 -10.9165933 1.5813420 552s [121] 0.1978278 2.9257678 1.5813420 1.5813420 -10.9165933 1.5813420 552s [127] -8.0465951 2.9257678 1.5813420 2.9257678 1.5813420 -8.0465951 552s [133] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257678 552s [139] 2.9257678 -10.9165933 0.1978278 1.5813420 -10.9165933 1.5813420 552s [145] 2.9257678 1.5813420 0.1978278 1.5813420 -10.9165933 -10.9165933 552s [151] -8.0465951 2.9257678 -10.9165933 -8.0465951 2.9257678 -8.0465951 552s [157] 0.1978278 0.1978278 1.5813420 -10.9165933 1.5813420 1.5813420 552s [163] -8.0465951 -8.0465951 1.5813420 1.5813420 1.5813420 1.5813420 552s [169] -8.0465951 0.1978278 -10.9165933 2.9257678 1.5813420 0.1978278 552s [175] 1.5813420 2.9257678 2.9257678 1.5813420 1.5813420 1.5813420 552s [181] 1.5813420 1.5813420 -8.0465951 2.9257678 -10.9165933 1.5813420 552s [187] 1.5813420 1.5813420 -8.0465951 2.9257678 1.5813420 2.9257678 552s [193] -8.0465951 2.9257678 1.5813420 1.5813420 1.5813420 -10.9165933 552s [199] 0.1978278 -8.0465951 1.5813420 -8.0465951 1.5813420 -10.9165933 552s [205] 1.5813420 2.9257678 1.5813420 2.9257678 1.5813420 -8.0465951 552s [211] -8.0465951 1.5813420 2.9257678 2.9257678 -8.0465951 -10.9165933 552s [217] 2.9257678 1.5813420 1.5813420 -10.9165933 2.9257678 1.5813420 552s [223] 1.5813420 -10.9165933 2.9257678 0.1978278 1.5813420 -8.0465951 552s [229] 1.5813420 -10.9165933 1.5813420 1.5813420 2.9257678 -10.9165933 552s [235] 1.5813420 1.5813420 2.9257678 -10.9165933 2.9257678 2.9257678 552s [241] 1.5813420 2.9257678 -10.9165933 -8.0465951 1.5813420 2.9257678 552s [247] 1.5813420 1.5813420 2.9257678 -8.0465951 -10.9165933 -10.9165933 552s [253] 0.1978278 -8.0465951 1.5813420 -8.0465951 2.9257678 -10.9165933 552s [259] 1.5813420 1.5813420 1.5813420 1.5813420 0.1978278 -10.9165933 552s [265] -10.9165933 -10.9165933 -10.9165933 -10.9165933 -10.9165933 1.5813420 552s [271] 2.9257678 2.9257678 -8.0465951 1.5813420 1.5813420 1.5813420 552s [277] -8.0465951 2.9257678 1.5813420 2.9257678 1.5813420 1.5813420 552s [283] 1.5813420 1.5813420 -8.0465951 2.9257678 1.5813420 0.1978278 552s [289] -10.9165933 1.5813420 1.5813420 -10.9165933 -8.0465951 1.5813420 552s [295] -10.9165933 -10.9165933 2.9257678 -10.9165933 1.5813420 2.9257678 552s [301] 1.5813420 1.5813420 2.9257678 1.5813420 1.5813420 -8.0465951 552s [307] 1.5813420 -8.0465951 0.1978278 -8.0465951 -8.0465951 -10.9165933 552s [313] 2.9257678 -10.9165933 1.5813420 -8.0465951 2.9257678 -10.9165933 552s [319] 2.9257678 0.1978278 1.5813420 -10.9165933 1.5813420 1.5813420 552s [325] -10.9165933 2.9257678 2.9257678 2.9257678 2.9257678 0.1978278 552s [331] -8.0465951 -10.9165933 1.5813420 -10.9165933 1.5813420 2.9257678 552s [337] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257678 552s [343] 1.5813420 -8.0465951 2.9257678 2.9257678 -8.0465951 0.1978278 552s [349] -8.0465951 1.5813420 1.5813420 1.5813420 2.9257678 552s 552s $se.fit 552s [1] 0.3179632 0.3179632 0.4944930 0.5940988 0.4944930 0.4944930 0.5551694 552s [8] 0.5551694 0.4944930 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 552s [15] 0.3179632 0.3179632 0.3179632 0.3179632 0.5551694 0.3179632 0.3179632 552s [22] 0.5551694 0.4944930 0.4944930 0.5551694 0.5551694 0.5940988 0.3179632 552s [29] 0.5940988 0.5940988 0.4944930 0.5551694 0.5590023 0.3179632 0.5551694 552s [36] 0.4944930 0.4944930 0.3179632 0.4944930 0.5940988 0.3179632 0.3179632 552s [43] 0.3179632 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 0.4944930 552s [50] 0.4944930 0.3179632 0.5551694 0.3179632 0.3179632 0.5551694 0.3179632 552s [57] 0.5551694 0.4944930 0.3179632 0.5940988 0.3179632 0.4944930 0.3179632 552s [64] 0.4944930 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 552s [71] 0.3179632 0.5940988 0.3179632 0.3179632 0.5551694 0.4944930 0.5551694 552s [78] 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.5940988 552s [85] 0.3179632 0.3179632 0.3179632 0.5551694 0.5551694 0.5551694 0.5551694 552s [92] 0.5940988 0.3179632 0.3179632 0.5940988 0.3179632 0.3179632 0.5940988 552s [99] 0.3179632 0.5551694 0.3179632 0.5551694 0.5940988 0.5940988 0.5940988 552s [106] 0.3179632 0.4944930 0.3179632 0.5940988 0.5551694 0.4944930 0.5940988 552s [113] 0.3179632 0.5551694 0.3179632 0.5551694 0.4944930 0.3179632 0.5551694 552s [120] 0.3179632 0.5590023 0.4944930 0.3179632 0.3179632 0.5551694 0.3179632 552s [127] 0.5940988 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 0.3179632 552s [134] 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.4944930 0.5551694 552s [141] 0.5590023 0.3179632 0.5551694 0.3179632 0.4944930 0.3179632 0.5590023 552s [148] 0.3179632 0.5551694 0.5551694 0.5940988 0.4944930 0.5551694 0.5940988 552s [155] 0.4944930 0.5940988 0.5590023 0.5590023 0.3179632 0.5551694 0.3179632 552s [162] 0.3179632 0.5940988 0.5940988 0.3179632 0.3179632 0.3179632 0.3179632 552s [169] 0.5940988 0.5590023 0.5551694 0.4944930 0.3179632 0.5590023 0.3179632 552s [176] 0.4944930 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 552s [183] 0.5940988 0.4944930 0.5551694 0.3179632 0.3179632 0.3179632 0.5940988 552s [190] 0.4944930 0.3179632 0.4944930 0.5940988 0.4944930 0.3179632 0.3179632 552s [197] 0.3179632 0.5551694 0.5590023 0.5940988 0.3179632 0.5940988 0.3179632 552s [204] 0.5551694 0.3179632 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 552s [211] 0.5940988 0.3179632 0.4944930 0.4944930 0.5940988 0.5551694 0.4944930 552s [218] 0.3179632 0.3179632 0.5551694 0.4944930 0.3179632 0.3179632 0.5551694 552s [225] 0.4944930 0.5590023 0.3179632 0.5940988 0.3179632 0.5551694 0.3179632 552s [232] 0.3179632 0.4944930 0.5551694 0.3179632 0.3179632 0.4944930 0.5551694 552s [239] 0.4944930 0.4944930 0.3179632 0.4944930 0.5551694 0.5940988 0.3179632 552s [246] 0.4944930 0.3179632 0.3179632 0.4944930 0.5940988 0.5551694 0.5551694 552s [253] 0.5590023 0.5940988 0.3179632 0.5940988 0.4944930 0.5551694 0.3179632 552s [260] 0.3179632 0.3179632 0.3179632 0.5590023 0.5551694 0.5551694 0.5551694 552s [267] 0.5551694 0.5551694 0.5551694 0.3179632 0.4944930 0.4944930 0.5940988 552s [274] 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 0.4944930 552s [281] 0.3179632 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 552s [288] 0.5590023 0.5551694 0.3179632 0.3179632 0.5551694 0.5940988 0.3179632 552s [295] 0.5551694 0.5551694 0.4944930 0.5551694 0.3179632 0.4944930 0.3179632 552s [302] 0.3179632 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 552s [309] 0.5590023 0.5940988 0.5940988 0.5551694 0.4944930 0.5551694 0.3179632 552s [316] 0.5940988 0.4944930 0.5551694 0.4944930 0.5590023 0.3179632 0.5551694 552s [323] 0.3179632 0.3179632 0.5551694 0.4944930 0.4944930 0.4944930 0.4944930 552s [330] 0.5590023 0.5940988 0.5551694 0.3179632 0.5551694 0.3179632 0.4944930 552s [337] 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.3179632 552s [344] 0.5940988 0.4944930 0.4944930 0.5940988 0.5590023 0.5940988 0.3179632 552s [351] 0.3179632 0.3179632 0.4944930 552s 552s [1] 50.13644 552s [1] 2052.27 552s [1] 2052.27 552s Dose Response Model 552s 552s Model: sigEmax 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -13.6642 -2.5494 -0.0589 3.1494 10.8255 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -9.3604 8.43e-01 552s eMax 18.0312 4.04e+00 552s ed50 427.8168 1.83e+02 552s h 1.3276 3.36e-01 552s age -0.0117 8.11e-03 552s centergreen -0.7488 7.57e-01 552s centerred -0.8859 7.12e-01 552s centersilver -1.4084 7.52e-01 552s centeryellow -1.4438 7.33e-01 552s 552s Residual standard error: 4.36 552s Degrees of freedom: 344 552s 552s Formula: y ~ cbind(XX, sigEmax(x, 0, 1, ed50, h)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s ed50 427.813485 182.738231 2.341 0.0198 * 552s h 1.327626 0.335875 3.953 9.38e-05 *** 552s .lin.(Intercept) -9.360422 0.842795 -11.106 < 2e-16 *** 552s .lin.centergreen -0.748766 0.757412 -0.989 0.3236 552s .lin.centerred -0.885871 0.711909 -1.244 0.2142 552s .lin.centersilver -1.408359 0.752071 -1.873 0.0620 . 552s .lin.centeryellow -1.443811 0.733469 -1.968 0.0498 * 552s .lin.age -0.011703 0.008114 -1.442 0.1501 552s .lin7 18.031101 4.042408 4.460 1.11e-05 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 4.36 on 344 degrees of freedom 552s 552s Number of iterations to convergence: 4 552s Achieved convergence tolerance: 7.015e-06 552s 552s e0 eMax ed50 h 552s e0 0.710302651 -4.248050e-01 12.9547646 5.611113e-02 552s eMax -0.424805031 1.634158e+01 694.3472386 -1.241172e+00 552s ed50 12.954764633 6.943472e+02 33394.5386146 -4.820462e+01 552s h 0.056111134 -1.241172e+00 -48.2046174 1.128111e-01 552s age -0.003282055 -7.347999e-04 -0.0251683 3.613375e-05 552s centergreen -0.239527553 2.751352e-02 1.4126289 -4.650674e-03 552s centerred -0.290825609 -1.412230e-01 -9.3345325 5.133219e-03 552s centersilver -0.296694203 -2.684223e-01 -15.5401130 1.239080e-02 552s centeryellow -0.294618448 -1.827692e-01 -11.6914478 8.045886e-03 552s age centergreen centerred centersilver 552s e0 -3.282055e-03 -0.2395275534 -2.908256e-01 -2.966942e-01 552s eMax -7.347999e-04 0.0275135152 -1.412230e-01 -2.684223e-01 552s ed50 -2.516830e-02 1.4126288561 -9.334532e+00 -1.554011e+01 552s h 3.613375e-05 -0.0046506738 5.133219e-03 1.239080e-02 552s age 6.584109e-05 -0.0004705249 3.847994e-05 1.268608e-04 552s centergreen -4.705249e-04 0.5736725480 2.674552e-01 2.669211e-01 552s centerred 3.847994e-05 0.2674552437 5.068148e-01 2.741110e-01 552s centersilver 1.268608e-04 0.2669210775 2.741110e-01 5.656114e-01 552s centeryellow 3.360823e-05 0.2672881708 2.729000e-01 2.753064e-01 552s centeryellow 552s e0 -2.946184e-01 552s eMax -1.827692e-01 552s ed50 -1.169145e+01 552s h 8.045886e-03 552s age 3.360823e-05 552s centergreen 2.672882e-01 552s centerred 2.729000e-01 552s centersilver 2.753064e-01 552s centeryellow 5.379774e-01 552s ed50 h .lin.(Intercept) .lin.centergreen 552s ed50 3.339326e+04 -4.820368e+01 12.954858536 1.4125956498 552s h -4.820368e+01 1.128119e-01 0.056111300 -0.0046506961 552s .lin.(Intercept) 1.295486e+01 5.611130e-02 0.710302646 -0.2395275486 552s .lin.centergreen 1.412596e+00 -4.650696e-03 -0.239527549 0.5736725489 552s .lin.centerred -9.334399e+00 5.133264e-03 -0.290825609 0.2674552405 552s .lin.centersilver -1.553987e+01 1.239088e-02 -0.296694200 0.2669210724 552s .lin.centeryellow -1.169127e+01 8.045945e-03 -0.294618447 0.2672881668 552s .lin.age -2.516784e-02 3.613396e-05 -0.003282055 -0.0004705249 552s .lin7 6.943216e+02 -1.241157e+00 -0.424801861 0.0275129941 552s .lin.centerred .lin.centersilver .lin.centeryellow 552s ed50 -9.334399e+00 -1.553987e+01 -1.169127e+01 552s h 5.133264e-03 1.239088e-02 8.045945e-03 552s .lin.(Intercept) -2.908256e-01 -2.966942e-01 -2.946184e-01 552s .lin.centergreen 2.674552e-01 2.669211e-01 2.672882e-01 552s .lin.centerred 5.068148e-01 2.741110e-01 2.729000e-01 552s .lin.centersilver 2.741110e-01 5.656114e-01 2.753064e-01 552s .lin.centeryellow 2.729000e-01 2.753064e-01 5.379774e-01 552s .lin.age 3.847993e-05 1.268608e-04 3.360822e-05 552s .lin7 -1.412207e-01 -2.684181e-01 -1.827662e-01 552s .lin.age .lin7 552s ed50 -2.516784e-02 694.321579932 552s h 3.613396e-05 -1.241156974 552s .lin.(Intercept) -3.282055e-03 -0.424801861 552s .lin.centergreen -4.705249e-04 0.027512994 552s .lin.centerred 3.847993e-05 -0.141220710 552s .lin.centersilver 1.268608e-04 -0.268418091 552s .lin.centeryellow 3.360822e-05 -0.182766244 552s .lin.age 6.584109e-05 -0.000734791 552s .lin7 -7.347910e-04 16.341065046 552s $fit 552s [1] 0.000000 2.286007 552s 552s $se.fit 552s [1] 0.0000000 0.7638951 552s 552s $fit 552s [1] -11.353936 -9.067928 552s 552s $se.fit 552s [1] 0.7291152 0.7547668 552s 552s [1] 50.56495 552s [1] 336.0966 552s [1] 336.0966 552s Dose Response Model 552s 552s Model: logistic 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -6.606 -1.402 -0.298 1.561 5.618 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -8.93 1.09 552s eMax 7.45 1.19 552s ed50 288.28 49.89 552s delta 43.71 37.57 552s 552s Residual standard error: 2.32 552s Degrees of freedom: 69 552s 552s Formula: y ~ logistic(x, e0, emax, ed50, delta) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s e0 -8.931 1.092 -8.179 9.42e-12 *** 552s emax 7.453 1.192 6.251 2.94e-08 *** 552s ed50 288.282 49.890 5.778 1.99e-07 *** 552s delta 43.709 37.566 1.164 0.249 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 2.323 on 69 degrees of freedom 552s 552s Number of iterations to convergence: 5 552s Achieved convergence tolerance: 1.876e-07 552s 552s e0 eMax ed50 delta 552s e0 1.192360 -1.220565 45.77141 -33.34815 552s eMax -1.220565 1.421491 -43.96678 35.28564 552s ed50 45.771406 -43.966777 2488.99422 -1733.71539 552s delta -33.348147 35.285635 -1733.71539 1411.22527 552s e0 emax ed50 delta 552s e0 1.192360 -1.220566 45.77134 -33.34807 552s emax -1.220566 1.421491 -43.96671 35.28556 552s ed50 45.771344 -43.966710 2488.98697 -1733.70785 552s delta -33.348068 35.285556 -1733.70785 1411.21841 552s $fit 552s [1] 0.0000000 5.6020563 7.4419763 7.4430636 5.6020563 0.3578039 7.4430636 552s [8] 0.3578039 7.4130064 7.4419763 5.6020563 5.6020563 5.6020563 5.6020563 552s [15] 5.6020563 5.6020563 7.4130064 0.3578039 0.3578039 7.4419763 0.3578039 552s [22] 7.4430636 0.3578039 7.4419763 7.4430636 0.3578039 7.4419763 7.4419763 552s [29] 5.6020563 0.0000000 7.4419763 5.6020563 7.4130064 7.4130064 7.4430636 552s [36] 0.0000000 7.4419763 7.4430636 5.6020563 5.6020563 5.6020563 7.4419763 552s [43] 5.6020563 0.3578039 7.4130064 5.6020563 7.4419763 0.3578039 5.6020563 552s [50] 0.0000000 5.6020563 7.4130064 7.4430636 5.6020563 0.3578039 7.4419763 552s [57] 7.4130064 7.4430636 7.4419763 7.4430636 0.0000000 5.6020563 5.6020563 552s [64] 5.6020563 7.4419763 5.6020563 7.4419763 7.4130064 7.4419763 5.6020563 552s [71] 5.6020563 0.3578039 5.6020563 552s 552s $se.fit 552s [1] 0.000000 1.134891 1.131632 1.137062 1.134891 1.244804 1.137062 1.244804 552s [9] 1.051179 1.131632 1.134891 1.134891 1.134891 1.134891 1.134891 1.134891 552s [17] 1.051179 1.244804 1.244804 1.131632 1.244804 1.137062 1.244804 1.131632 552s [25] 1.137062 1.244804 1.131632 1.131632 1.134891 0.000000 1.131632 1.134891 552s [33] 1.051179 1.051179 1.137062 0.000000 1.131632 1.137062 1.134891 1.134891 552s [41] 1.134891 1.131632 1.134891 1.244804 1.051179 1.134891 1.131632 1.244804 552s [49] 1.134891 0.000000 1.134891 1.051179 1.137062 1.134891 1.244804 1.131632 552s [57] 1.051179 1.137062 1.131632 1.137062 0.000000 1.134891 1.134891 1.134891 552s [65] 1.131632 1.134891 1.131632 1.051179 1.131632 1.134891 1.134891 1.244804 552s [73] 1.134891 552s 552s $fit 552s [1] -8.920547 -3.318491 -1.478571 -1.477483 -3.318491 -8.562743 -1.477483 552s [8] -8.562743 -1.507541 -1.478571 -3.318491 -3.318491 -3.318491 -3.318491 552s [15] -3.318491 -3.318491 -1.507541 -8.562743 -8.562743 -1.478571 -8.562743 552s [22] -1.477483 -8.562743 -1.478571 -1.477483 -8.562743 -1.478571 -1.478571 552s [29] -3.318491 -8.920547 -1.478571 -3.318491 -1.507541 -1.507541 -1.477483 552s [36] -8.920547 -1.478571 -1.477483 -3.318491 -3.318491 -3.318491 -1.478571 552s [43] -3.318491 -8.562743 -1.507541 -3.318491 -1.478571 -8.562743 -3.318491 552s [50] -8.920547 -3.318491 -1.507541 -1.477483 -3.318491 -8.562743 -1.478571 552s [57] -1.507541 -1.477483 -1.478571 -1.477483 -8.920547 -3.318491 -3.318491 552s [64] -3.318491 -1.478571 -3.318491 -1.478571 -1.507541 -1.478571 -3.318491 552s [71] -3.318491 -8.562743 -3.318491 552s 552s $se.fit 552s [1] 1.0345960 0.4644528 0.4144011 0.4155112 0.4644528 0.6986843 0.4155112 552s [8] 0.6986843 0.4088615 0.4144011 0.4644528 0.4644528 0.4644528 0.4644528 552s [15] 0.4644528 0.4644528 0.4088615 0.6986843 0.6986843 0.4144011 0.6986843 552s [22] 0.4155112 0.6986843 0.4144011 0.4155112 0.6986843 0.4144011 0.4144011 552s [29] 0.4644528 1.0345960 0.4144011 0.4644528 0.4088615 0.4088615 0.4155112 552s [36] 1.0345960 0.4144011 0.4155112 0.4644528 0.4644528 0.4644528 0.4144011 552s [43] 0.4644528 0.6986843 0.4088615 0.4644528 0.4144011 0.6986843 0.4644528 552s [50] 1.0345960 0.4644528 0.4088615 0.4155112 0.4644528 0.6986843 0.4144011 552s [57] 0.4088615 0.4155112 0.4144011 0.4155112 1.0345960 0.4644528 0.4644528 552s [64] 0.4644528 0.4144011 0.4644528 0.4144011 0.4088615 0.4144011 0.4644528 552s [71] 0.4644528 0.6986843 0.4644528 552s 552s [1] 174.1673 552s [1] 345.1575 552s [1] 345.1575 552s Dose Response Model 552s 552s Model: logistic 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -6.924 -1.388 -0.179 1.618 5.265 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -8.98657 1.419 552s eMax 7.65181 1.269 552s ed50 286.51988 50.767 552s delta 43.51040 36.726 552s age -0.00402 0.011 552s centergreen -0.12880 0.873 552s centerred 0.10022 0.975 552s centersilver 0.60689 0.985 552s centeryellow 0.06974 0.968 552s 552s Residual standard error: 2.4 552s Degrees of freedom: 64 552s 552s Formula: y ~ cbind(XX, logistic(x, 0, 1, ed50, delta)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s ed50 286.519963 50.768013 5.644 4.08e-07 *** 552s delta 43.510064 36.726739 1.185 0.241 552s .lin.(Intercept) -8.986562 1.418992 -6.333 2.71e-08 *** 552s .lin.centergreen -0.128797 0.873355 -0.147 0.883 552s .lin.centerred 0.100221 0.975122 0.103 0.918 552s .lin.centersilver 0.606894 0.985016 0.616 0.540 552s .lin.centeryellow 0.069737 0.968243 0.072 0.943 552s .lin.age -0.004017 0.011024 -0.364 0.717 552s .lin7 7.651799 1.268713 6.031 8.96e-08 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 2.396 on 64 degrees of freedom 552s 552s Number of iterations to convergence: 4 552s Achieved convergence tolerance: 6.656e-06 552s 552s e0 eMax ed50 delta 552s e0 2.013542599 -1.386381625 4.801326e+01 -3.320465e+01 552s eMax -1.386381625 1.609637810 -4.594280e+01 3.537786e+01 552s ed50 48.013263826 -45.942796881 2.577339e+03 -1.719550e+03 552s delta -33.204645933 35.377861681 -1.719550e+03 1.348832e+03 552s age -0.006268645 0.001147196 1.238916e-02 -1.182615e-04 552s centergreen -0.334052153 -0.153718220 1.779756e+00 -1.607538e+00 552s centerred -0.399667176 -0.068891593 -2.561521e+00 7.131922e-01 552s centersilver -0.538856175 0.113916607 8.446386e-02 -1.524166e+00 552s centeryellow -0.463856043 -0.044371048 -3.153773e+00 1.284203e+00 552s age centergreen centerred centersilver 552s e0 -0.0062686454 -0.3340521534 -0.399667176 -0.5388561747 552s eMax 0.0011471962 -0.1537182199 -0.068891593 0.1139166068 552s ed50 0.0123891577 1.7797560751 -2.561520562 0.0844638606 552s delta -0.0001182615 -1.6075377781 0.713192224 -1.5241663467 552s age 0.0001215321 -0.0007558322 -0.001348561 -0.0006628626 552s centergreen -0.0007558322 0.7627491953 0.499187248 0.4609636575 552s centerred -0.0013485609 0.4991872483 0.950863865 0.4738663247 552s centersilver -0.0006628626 0.4609636575 0.473866325 0.9702565708 552s centeryellow -0.0003700776 0.4923423826 0.498378928 0.4677967285 552s centeryellow 552s e0 -0.4638560434 552s eMax -0.0443710477 552s ed50 -3.1537729773 552s delta 1.2842028590 552s age -0.0003700776 552s centergreen 0.4923423826 552s centerred 0.4983789279 552s centersilver 0.4677967285 552s centeryellow 0.9374951281 552s ed50 delta .lin.(Intercept) .lin.centergreen 552s ed50 2.577391e+03 -1.719586e+03 48.013675185 1.7797792085 552s delta -1.719586e+03 1.348853e+03 -33.204886930 -1.6075529969 552s .lin.(Intercept) 4.801368e+01 -3.320489e+01 2.013538892 -0.3340522689 552s .lin.centergreen 1.779779e+00 -1.607553e+00 -0.334052269 0.7627491915 552s .lin.centerred -2.561536e+00 7.132042e-01 -0.399667184 0.4991872439 552s .lin.centersilver 8.448334e-02 -1.524165e+00 -0.538856203 0.4609636569 552s .lin.centeryellow -3.153788e+00 1.284211e+00 -0.463855840 0.4923423903 552s .lin.age 1.238909e-02 -1.181868e-04 -0.006268647 -0.0007558323 552s .lin7 -4.594320e+01 3.537808e+01 -1.386377258 -0.1537180630 552s .lin.centerred .lin.centersilver .lin.centeryellow 552s ed50 -2.561536031 0.0844833421 -3.1537878657 552s delta 0.713204179 -1.5241654679 1.2842107129 552s .lin.(Intercept) -0.399667184 -0.5388562027 -0.4638558403 552s .lin.centergreen 0.499187244 0.4609636569 0.4923423903 552s .lin.centerred 0.950863862 0.4738663195 0.4983789308 552s .lin.centersilver 0.473866320 0.9702565794 0.4677967413 552s .lin.centeryellow 0.498378931 0.4677967413 0.9374951277 552s .lin.age -0.001348561 -0.0006628628 -0.0003700776 552s .lin7 -0.068891567 0.1139166792 -0.0443712829 552s .lin.age .lin7 552s ed50 0.0123890859 -45.943204762 552s delta -0.0001181868 35.378079613 552s .lin.(Intercept) -0.0062686471 -1.386377258 552s .lin.centergreen -0.0007558323 -0.153718063 552s .lin.centerred -0.0013485609 -0.068891567 552s .lin.centersilver -0.0006628628 0.113916679 552s .lin.centeryellow -0.0003700776 -0.044371283 552s .lin.age 0.0001215321 0.001147198 552s .lin7 0.0011471982 1.609632577 552s $fit 552s [1] 0.00000000 0.09322688 552s 552s $se.fit 552s [1] 0.0000000 0.4246053 552s 552s $fit 552s [1] -8.389208 -8.295981 552s 552s $se.fit 552s [1] 1.306647 1.060317 552s 552s [1] 46.37307 552s [1] -1501.193 552s [1] -1501.193 552s Dose Response Model 552s 552s Model: exponential 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -2.70e-01 -5.95e-02 7.18e-05 5.87e-02 2.44e-01 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -0.466 6.03e-03 552s e1 0.125 9.54e-02 552s delta 972.943 4.86e+02 552s 552s Residual standard error: 0.0841 552s Degrees of freedom: 710 552s 552s Formula: y ~ exponential(x, e0, e1, delta) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s e0 -0.466094 0.006025 -77.359 <2e-16 *** 552s e1 0.124504 0.095374 1.305 0.1922 552s delta 972.943147 485.901518 2.002 0.0456 * 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.08415 on 710 degrees of freedom 552s 552s Number of iterations to convergence: 0 552s Achieved convergence tolerance: 9.117e-09 552s 552s e0 e1 delta 552s e0 3.630154e-05 -0.0004207859 -2.060286 552s e1 -4.207859e-04 0.0090961441 46.252662 552s delta -2.060286e+00 46.2526621113 236100.508253 552s e0 e1 delta 552s e0 3.630152e-05 -0.0004207855 -2.060284 552s e1 -4.207855e-04 0.0090961353 46.252618 552s delta -2.060284e+00 46.2526179204 236100.284932 552s $fit 552s [1] 0.00000000 0.03271671 0.00000000 0.11169230 0.01605388 0.18278309 552s [7] 0.18278309 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 552s [13] 0.11169230 0.01605388 0.18278309 0.18278309 0.18278309 0.18278309 552s [19] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.00000000 552s [25] 0.01605388 0.00000000 0.11169230 0.00000000 0.18278309 0.03271671 552s [31] 0.18278309 0.01605388 0.00000000 0.03271671 0.00000000 0.03271671 552s [37] 0.03271671 0.11169230 0.00000000 0.03271671 0.01605388 0.18278309 552s [43] 0.01605388 0.03271671 0.01605388 0.01605388 0.01605388 0.18278309 552s [49] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 552s [55] 0.03271671 0.03271671 0.01605388 0.00000000 0.11169230 0.18278309 552s [61] 0.00000000 0.18278309 0.18278309 0.03271671 0.03271671 0.01605388 552s [67] 0.00000000 0.03271671 0.18278309 0.01605388 0.03271671 0.00000000 552s [73] 0.00000000 0.01605388 0.18278309 0.01605388 0.00000000 0.01605388 552s [79] 0.01605388 0.01605388 0.18278309 0.18278309 0.00000000 0.01605388 552s [85] 0.11169230 0.11169230 0.01605388 0.18278309 0.11169230 0.03271671 552s [91] 0.03271671 0.18278309 0.01605388 0.11169230 0.03271671 0.00000000 552s [97] 0.18278309 0.00000000 0.00000000 0.01605388 0.11169230 0.00000000 552s [103] 0.11169230 0.03271671 0.11169230 0.18278309 0.01605388 0.00000000 552s [109] 0.11169230 0.01605388 0.11169230 0.00000000 0.00000000 0.01605388 552s [115] 0.11169230 0.01605388 0.11169230 0.11169230 0.18278309 0.01605388 552s [121] 0.11169230 0.18278309 0.00000000 0.03271671 0.18278309 0.01605388 552s [127] 0.01605388 0.03271671 0.03271671 0.11169230 0.11169230 0.18278309 552s [133] 0.00000000 0.00000000 0.01605388 0.01605388 0.01605388 0.01605388 552s [139] 0.01605388 0.18278309 0.18278309 0.01605388 0.00000000 0.18278309 552s [145] 0.00000000 0.01605388 0.18278309 0.03271671 0.18278309 0.01605388 552s [151] 0.00000000 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 552s [157] 0.01605388 0.01605388 0.00000000 0.11169230 0.00000000 0.00000000 552s [163] 0.01605388 0.03271671 0.03271671 0.00000000 0.11169230 0.18278309 552s [169] 0.18278309 0.01605388 0.03271671 0.03271671 0.11169230 0.01605388 552s [175] 0.01605388 0.03271671 0.03271671 0.00000000 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0.006025076 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 552s [157] 0.003835233 0.003835233 0.006025076 0.006884091 0.006025076 0.006025076 552s [163] 0.003835233 0.004212735 0.004212735 0.006025076 0.006884091 0.007313632 552s [169] 0.007313632 0.003835233 0.004212735 0.004212735 0.006884091 0.003835233 552s [175] 0.003835233 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 552s [181] 0.006884091 0.003835233 0.004212735 0.007313632 0.006884091 0.003835233 552s [187] 0.006884091 0.004212735 0.003835233 0.004212735 0.006025076 0.007313632 552s [193] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.006884091 552s [199] 0.003835233 0.006025076 0.006884091 0.006884091 0.003835233 0.004212735 552s [205] 0.006025076 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 552s [211] 0.003835233 0.004212735 0.003835233 0.004212735 0.003835233 0.007313632 552s [217] 0.003835233 0.006884091 0.003835233 0.007313632 0.006884091 0.003835233 552s [223] 0.006884091 0.007313632 0.004212735 0.007313632 0.004212735 0.006884091 552s [229] 0.006884091 0.006025076 0.003835233 0.003835233 0.006884091 0.006025076 552s [235] 0.007313632 0.004212735 0.003835233 0.006884091 0.007313632 0.007313632 552s [241] 0.003835233 0.004212735 0.006025076 0.004212735 0.007313632 0.003835233 552s [247] 0.003835233 0.004212735 0.003835233 0.006884091 0.004212735 0.004212735 552s [253] 0.006884091 0.006025076 0.006025076 0.006025076 0.003835233 0.006884091 552s [259] 0.007313632 0.003835233 0.007313632 0.003835233 0.007313632 0.004212735 552s [265] 0.003835233 0.004212735 0.003835233 0.007313632 0.007313632 0.004212735 552s [271] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.003835233 552s [277] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.004212735 552s [283] 0.007313632 0.003835233 0.006025076 0.003835233 0.003835233 0.003835233 552s [289] 0.006884091 0.004212735 0.004212735 0.003835233 0.004212735 0.003835233 552s [295] 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 552s [301] 0.006884091 0.006884091 0.007313632 0.006884091 0.003835233 0.003835233 552s [307] 0.003835233 0.004212735 0.004212735 0.004212735 0.003835233 0.007313632 552s [313] 0.004212735 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 552s [319] 0.004212735 0.006884091 0.004212735 0.003835233 0.003835233 0.003835233 552s [325] 0.007313632 0.006884091 0.003835233 0.004212735 0.007313632 0.003835233 552s [331] 0.006884091 0.004212735 0.003835233 0.004212735 0.004212735 0.003835233 552s [337] 0.003835233 0.006884091 0.003835233 0.004212735 0.003835233 0.003835233 552s [343] 0.006025076 0.003835233 0.004212735 0.003835233 0.006884091 0.007313632 552s [349] 0.003835233 0.003835233 0.003835233 0.007313632 0.006884091 0.004212735 552s [355] 0.007313632 0.003835233 0.006884091 0.004212735 0.004212735 0.003835233 552s [361] 0.003835233 0.003835233 0.003835233 0.006025076 0.004212735 0.007313632 552s [367] 0.004212735 0.007313632 0.007313632 0.003835233 0.003835233 0.006884091 552s [373] 0.003835233 0.006884091 0.003835233 0.007313632 0.007313632 0.003835233 552s [379] 0.007313632 0.007313632 0.006884091 0.006884091 0.007313632 0.004212735 552s [385] 0.007313632 0.004212735 0.007313632 0.003835233 0.006884091 0.006025076 552s [391] 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 0.004212735 552s [397] 0.004212735 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 552s [403] 0.006884091 0.004212735 0.004212735 0.006025076 0.004212735 0.003835233 552s [409] 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 0.006884091 552s [415] 0.003835233 0.006884091 0.007313632 0.006884091 0.003835233 0.004212735 552s [421] 0.003835233 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 552s [427] 0.004212735 0.006025076 0.007313632 0.003835233 0.006884091 0.003835233 552s [433] 0.003835233 0.003835233 0.006025076 0.003835233 0.006884091 0.006025076 552s [439] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 552s [445] 0.006025076 0.006025076 0.003835233 0.003835233 0.006025076 0.004212735 552s [451] 0.007313632 0.003835233 0.006884091 0.006025076 0.003835233 0.006025076 552s [457] 0.003835233 0.006025076 0.007313632 0.003835233 0.003835233 0.006884091 552s [463] 0.003835233 0.004212735 0.007313632 0.007313632 0.006884091 0.007313632 552s [469] 0.003835233 0.003835233 0.006025076 0.003835233 0.003835233 0.004212735 552s [475] 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 552s [481] 0.006025076 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 552s [487] 0.007313632 0.006884091 0.007313632 0.003835233 0.006884091 0.007313632 552s [493] 0.006884091 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 552s [499] 0.004212735 0.003835233 0.007313632 0.006884091 0.007313632 0.007313632 552s [505] 0.003835233 0.006025076 0.003835233 0.007313632 0.007313632 0.003835233 552s [511] 0.004212735 0.003835233 0.007313632 0.003835233 0.003835233 0.004212735 552s [517] 0.003835233 0.003835233 0.004212735 0.006025076 0.004212735 0.004212735 552s [523] 0.007313632 0.004212735 0.004212735 0.004212735 0.004212735 0.006025076 552s [529] 0.003835233 0.007313632 0.004212735 0.006884091 0.007313632 0.003835233 552s [535] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.006025076 552s [541] 0.004212735 0.006884091 0.004212735 0.007313632 0.004212735 0.003835233 552s [547] 0.004212735 0.006025076 0.006025076 0.007313632 0.004212735 0.006884091 552s [553] 0.006884091 0.003835233 0.006025076 0.004212735 0.006025076 0.003835233 552s [559] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.004212735 552s [565] 0.004212735 0.003835233 0.006884091 0.006884091 0.004212735 0.003835233 552s [571] 0.006884091 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 552s [577] 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 0.006884091 552s [583] 0.004212735 0.007313632 0.003835233 0.006884091 0.007313632 0.003835233 552s [589] 0.003835233 0.003835233 0.007313632 0.003835233 0.007313632 0.003835233 552s [595] 0.007313632 0.007313632 0.006884091 0.004212735 0.004212735 0.003835233 552s [601] 0.003835233 0.003835233 0.007313632 0.004212735 0.004212735 0.003835233 552s [607] 0.003835233 0.007313632 0.007313632 0.006884091 0.004212735 0.007313632 552s [613] 0.007313632 0.003835233 0.003835233 0.006025076 0.007313632 0.003835233 552s [619] 0.006884091 0.003835233 0.006884091 0.006025076 0.003835233 0.003835233 552s [625] 0.007313632 0.003835233 0.004212735 0.004212735 0.006025076 0.006025076 552s [631] 0.006025076 0.006025076 0.006025076 0.003835233 0.007313632 0.004212735 552s [637] 0.006025076 0.003835233 0.006884091 0.007313632 0.003835233 0.006884091 552s [643] 0.003835233 0.006025076 0.003835233 0.004212735 0.004212735 0.003835233 552s [649] 0.006025076 0.003835233 0.006884091 0.006884091 0.007313632 0.007313632 552s [655] 0.006884091 0.003835233 0.004212735 0.004212735 0.003835233 0.003835233 552s [661] 0.006025076 0.003835233 0.004212735 0.006884091 0.003835233 0.003835233 552s [667] 0.003835233 0.003835233 0.003835233 0.003835233 0.006025076 0.003835233 552s [673] 0.004212735 0.007313632 0.003835233 0.003835233 0.007313632 0.006025076 552s [679] 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 552s [685] 0.007313632 0.007313632 0.006884091 0.004212735 0.006025076 0.004212735 552s [691] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.003835233 552s [697] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 552s [703] 0.006884091 0.006884091 0.003835233 0.003835233 0.003835233 0.003835233 552s [709] 0.004212735 0.006884091 0.003835233 0.007313632 0.003835233 552s 552s [1] 573.604 552s [1] -1502.21 552s [1] -1502.21 552s Dose Response Model 552s 552s Model: exponential 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -2.72e-01 -5.96e-02 -5.44e-06 5.59e-02 2.43e-01 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -4.57e-01 1.03e-02 552s e1 1.24e-01 9.45e-02 552s delta 9.69e+02 4.79e+02 552s age -2.46e-04 1.09e-04 552s centergreen -2.26e-03 9.93e-03 552s centerred 7.10e-03 9.88e-03 552s centersilver 1.68e-02 1.02e-02 552s centeryellow -4.45e-03 1.01e-02 552s 552s Residual standard error: 0.0838 552s Degrees of freedom: 705 552s 552s Formula: y ~ cbind(XX, exponential(x, 0, 1, delta)) 552s 552s Parameters: 552s Estimate Std. Error t value Pr(>|t|) 552s delta 9.692e+02 4.795e+02 2.021 0.0436 * 552s .lin.(Intercept) -4.574e-01 1.035e-02 -44.200 <2e-16 *** 552s .lin.centergreen -2.256e-03 9.934e-03 -0.227 0.8204 552s .lin.centerred 7.104e-03 9.875e-03 0.719 0.4721 552s .lin.centersilver 1.682e-02 1.018e-02 1.652 0.0989 . 552s .lin.centeryellow -4.446e-03 1.005e-02 -0.442 0.6584 552s .lin.age -2.463e-04 1.090e-04 -2.259 0.0242 * 552s .lin7 1.244e-01 9.455e-02 1.316 0.1886 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.0838 on 705 degrees of freedom 552s 552s Number of iterations to convergence: 7 552s Achieved convergence tolerance: 8.761e-06 552s 552s e0 e1 delta age 552s e0 1.070950e-04 -3.644583e-04 -1.760351e+00 -6.235809e-07 552s e1 -3.644583e-04 8.939485e-03 4.524835e+01 -1.892275e-07 552s delta -1.760351e+00 4.524835e+01 2.299190e+05 -9.417515e-04 552s age -6.235809e-07 -1.892275e-07 -9.417515e-04 1.188604e-08 552s centergreen -4.990019e-05 -7.223388e-05 -3.668153e-01 4.308966e-08 552s centerred -5.090480e-05 -5.257813e-05 -2.765207e-01 2.992730e-08 552s centersilver -5.269569e-05 -5.104405e-05 -2.725147e-01 5.557593e-08 552s centeryellow -5.416568e-05 -3.395837e-05 -1.820279e-01 7.695026e-08 552s centergreen centerred centersilver centeryellow 552s e0 -4.990019e-05 -5.090480e-05 -5.269569e-05 -5.416568e-05 552s e1 -7.223388e-05 -5.257813e-05 -5.104405e-05 -3.395837e-05 552s delta -3.668153e-01 -2.765207e-01 -2.725147e-01 -1.820279e-01 552s age 4.308966e-08 2.992730e-08 5.557593e-08 7.695026e-08 552s centergreen 9.869293e-05 5.105736e-05 5.114013e-05 5.107251e-05 552s centerred 5.105736e-05 9.752101e-05 5.111632e-05 5.102188e-05 552s centersilver 5.114013e-05 5.111632e-05 1.036881e-04 5.122455e-05 552s centeryellow 5.107251e-05 5.102188e-05 5.122455e-05 1.010538e-04 552s delta .lin.(Intercept) .lin.centergreen 552s delta 2.299104e+05 -1.760315e+00 -3.668084e-01 552s .lin.(Intercept) -1.760315e+00 1.070949e-04 -4.990020e-05 552s .lin.centergreen -3.668084e-01 -4.990020e-05 9.869293e-05 552s .lin.centerred -2.765154e-01 -5.090480e-05 5.105736e-05 552s .lin.centersilver -2.725097e-01 -5.269570e-05 5.114013e-05 552s .lin.centeryellow -1.820244e-01 -5.416569e-05 5.107251e-05 552s .lin.age -9.417341e-04 -6.235810e-07 4.308966e-08 552s .lin7 4.524658e+01 -3.644504e-04 -7.223243e-05 552s .lin.centerred .lin.centersilver .lin.centeryellow 552s delta -2.765154e-01 -2.725097e-01 -1.820244e-01 552s .lin.(Intercept) -5.090480e-05 -5.269570e-05 -5.416569e-05 552s .lin.centergreen 5.105736e-05 5.114013e-05 5.107251e-05 552s .lin.centerred 9.752101e-05 5.111632e-05 5.102188e-05 552s .lin.centersilver 5.111632e-05 1.036881e-04 5.122455e-05 552s .lin.centeryellow 5.102188e-05 5.122455e-05 1.010538e-04 552s .lin.age 2.992730e-08 5.557593e-08 7.695026e-08 552s .lin7 -5.257703e-05 -5.104303e-05 -3.395768e-05 552s .lin.age .lin7 552s delta -9.417341e-04 4.524658e+01 552s .lin.(Intercept) -6.235810e-07 -3.644504e-04 552s .lin.centergreen 4.308966e-08 -7.223243e-05 552s .lin.centerred 2.992730e-08 -5.257703e-05 552s .lin.centersilver 5.557593e-08 -5.104303e-05 552s .lin.centeryellow 7.695026e-08 -3.395768e-05 552s .lin.age 1.188604e-08 -1.892238e-07 552s .lin7 -1.892238e-07 8.939124e-03 552s $fit 552s [1] 0.00000000 0.01352276 552s 552s $se.fit 552s [1] 0.000000000 0.003277925 552s 552s $fit 552s [1] -0.4697265 -0.4562037 552s 552s $se.fit 552s [1] 0.008628557 0.007549824 552s 552s [1] 571.7033 552s [1] 4189.744 552s [1] 4189.744 552s Dose Response Model 552s 552s Model: linear 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -20.3923 -4.1973 -0.0226 3.8448 25.3694 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -11.2122 0.393654 552s delta 0.0136 0.000531 552s 552s Residual standard error: 6.43 552s Degrees of freedom: 636 552s 552s Call: 552s lm(formula = y ~ x, data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -25.3694 -3.8448 0.0226 4.1973 20.3923 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -1.121e+01 3.937e-01 -28.48 <2e-16 *** 552s x 1.358e-02 5.313e-04 25.57 <2e-16 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 6.433 on 636 degrees of freedom 552s Multiple R-squared: 0.5069, Adjusted R-squared: 0.5061 552s F-statistic: 653.7 on 1 and 636 DF, p-value: < 2.2e-16 552s 552s e0 delta 552s e0 0.1549638101 -1.594693e-04 552s delta -0.0001594693 2.822434e-07 552s (Intercept) x 552s (Intercept) 0.1549638101 -1.594693e-04 552s x -0.0001594693 2.822434e-07 552s $fit 552s [1] 3.382287 6.560821 12.605469 12.605469 17.251020 0.000000 0.000000 552s [8] 6.560821 17.251020 3.382287 15.892672 3.382287 0.000000 9.671438 552s [15] 15.892672 17.251020 12.605469 17.251020 3.382287 17.251020 17.251020 552s [22] 9.671438 3.382287 12.605469 0.000000 12.605469 3.382287 6.560821 552s [29] 0.000000 17.251020 0.000000 9.671438 12.605469 3.382287 3.382287 552s [36] 0.000000 0.000000 12.605469 0.000000 12.605469 0.000000 15.892672 552s [43] 12.605469 15.892672 3.382287 17.251020 17.251020 6.560821 3.382287 552s [50] 0.000000 9.671438 17.251020 15.892672 0.000000 3.382287 17.251020 552s [57] 6.560821 17.251020 0.000000 3.382287 12.605469 12.605469 0.000000 552s [64] 0.000000 15.892672 15.892672 0.000000 12.605469 15.892672 3.382287 552s [71] 15.892672 6.560821 3.382287 17.251020 12.605469 0.000000 12.605469 552s [78] 12.605469 3.382287 0.000000 0.000000 0.000000 3.382287 3.382287 552s [85] 3.382287 6.560821 3.382287 0.000000 3.382287 17.251020 6.560821 552s [92] 3.382287 17.251020 9.671438 3.382287 0.000000 3.382287 3.382287 552s [99] 12.605469 0.000000 3.382287 3.382287 12.605469 0.000000 0.000000 552s [106] 17.251020 0.000000 6.560821 15.892672 17.251020 3.382287 17.251020 552s [113] 3.382287 0.000000 0.000000 3.382287 6.560821 0.000000 6.560821 552s [120] 3.382287 0.000000 0.000000 6.560821 15.892672 12.605469 12.605469 552s [127] 0.000000 17.251020 0.000000 17.251020 3.382287 0.000000 12.605469 552s [134] 17.251020 0.000000 3.382287 0.000000 6.560821 6.560821 6.560821 552s [141] 3.382287 17.251020 0.000000 0.000000 3.382287 0.000000 15.892672 552s [148] 17.251020 3.382287 15.892672 0.000000 17.251020 6.560821 3.382287 552s [155] 12.605469 6.560821 6.560821 3.382287 3.382287 0.000000 3.382287 552s [162] 0.000000 3.382287 12.605469 3.382287 0.000000 17.251020 0.000000 552s [169] 0.000000 3.382287 17.251020 3.382287 17.251020 15.892672 6.560821 552s [176] 12.605469 3.382287 0.000000 12.605469 0.000000 12.605469 17.251020 552s [183] 12.605469 0.000000 0.000000 12.605469 3.382287 12.605469 17.251020 552s [190] 3.382287 3.382287 17.251020 3.382287 6.560821 3.382287 17.251020 552s [197] 17.251020 0.000000 12.605469 0.000000 12.605469 3.382287 6.560821 552s [204] 12.605469 12.605469 3.382287 3.382287 12.605469 17.251020 12.605469 552s [211] 3.382287 3.382287 17.251020 0.000000 6.560821 3.382287 3.382287 552s [218] 0.000000 6.560821 0.000000 6.560821 6.560821 3.382287 0.000000 552s [225] 3.382287 3.382287 17.251020 3.382287 0.000000 17.251020 3.382287 552s [232] 6.560821 17.251020 0.000000 0.000000 3.382287 3.382287 12.605469 552s [239] 6.560821 12.605469 3.382287 12.605469 17.251020 6.560821 17.251020 552s [246] 17.251020 15.892672 0.000000 3.382287 3.382287 3.382287 0.000000 552s [253] 12.605469 15.892672 6.560821 3.382287 3.382287 0.000000 0.000000 552s [260] 12.605469 6.560821 3.382287 3.382287 12.605469 17.251020 0.000000 552s [267] 6.560821 15.892672 3.382287 15.892672 3.382287 12.605469 0.000000 552s [274] 17.251020 15.892672 6.560821 3.382287 12.605469 0.000000 3.382287 552s [281] 3.382287 12.605469 3.382287 0.000000 17.251020 15.892672 17.251020 552s [288] 3.382287 17.251020 3.382287 3.382287 3.382287 15.892672 0.000000 552s [295] 0.000000 17.251020 17.251020 12.605469 0.000000 12.605469 17.251020 552s [302] 15.892672 15.892672 0.000000 3.382287 12.605469 12.605469 15.892672 552s [309] 6.560821 15.892672 12.605469 12.605469 17.251020 0.000000 17.251020 552s [316] 3.382287 17.251020 3.382287 12.605469 0.000000 6.560821 3.382287 552s [323] 0.000000 15.892672 17.251020 17.251020 17.251020 3.382287 6.560821 552s [330] 0.000000 0.000000 12.605469 12.605469 12.605469 0.000000 12.605469 552s [337] 0.000000 15.892672 6.560821 17.251020 12.605469 12.605469 6.560821 552s [344] 0.000000 0.000000 17.251020 0.000000 0.000000 12.605469 0.000000 552s [351] 3.382287 3.382287 6.560821 17.251020 9.671438 0.000000 9.671438 552s [358] 9.671438 12.605469 3.382287 12.605469 3.382287 17.251020 0.000000 552s [365] 12.605469 0.000000 3.382287 0.000000 3.382287 6.560821 0.000000 552s [372] 6.560821 6.560821 17.251020 15.892672 0.000000 17.251020 0.000000 552s [379] 3.382287 17.251020 3.382287 12.605469 3.382287 3.382287 12.605469 552s [386] 3.382287 3.382287 0.000000 15.892672 0.000000 12.605469 0.000000 552s [393] 15.892672 6.560821 15.892672 15.892672 6.560821 6.560821 3.382287 552s [400] 3.382287 17.251020 17.251020 6.560821 12.605469 9.671438 15.892672 552s [407] 17.251020 6.560821 3.382287 0.000000 6.560821 6.560821 15.892672 552s [414] 3.382287 0.000000 0.000000 0.000000 0.000000 3.382287 3.382287 552s [421] 0.000000 3.382287 3.382287 12.605469 17.251020 17.251020 17.251020 552s [428] 0.000000 15.892672 17.251020 17.251020 0.000000 0.000000 17.251020 552s [435] 12.605469 6.560821 0.000000 0.000000 3.382287 0.000000 15.892672 552s [442] 12.605469 17.251020 3.382287 12.605469 0.000000 17.251020 0.000000 552s [449] 6.560821 12.605469 6.560821 12.605469 15.892672 12.605469 12.605469 552s [456] 0.000000 0.000000 3.382287 0.000000 3.382287 0.000000 0.000000 552s [463] 0.000000 17.251020 6.560821 17.251020 12.605469 12.605469 3.382287 552s [470] 17.251020 0.000000 3.382287 0.000000 6.560821 0.000000 0.000000 552s [477] 3.382287 15.892672 3.382287 12.605469 0.000000 3.382287 12.605469 552s [484] 6.560821 17.251020 9.671438 15.892672 17.251020 15.892672 0.000000 552s [491] 0.000000 3.382287 3.382287 17.251020 0.000000 6.560821 12.605469 552s [498] 12.605469 12.605469 3.382287 3.382287 3.382287 15.892672 0.000000 552s [505] 6.560821 3.382287 17.251020 3.382287 12.605469 12.605469 15.892672 552s [512] 0.000000 12.605469 17.251020 6.560821 0.000000 3.382287 0.000000 552s [519] 15.892672 0.000000 12.605469 12.605469 0.000000 17.251020 0.000000 552s [526] 9.671438 0.000000 3.382287 15.892672 3.382287 3.382287 3.382287 552s [533] 17.251020 15.892672 0.000000 0.000000 0.000000 15.892672 6.560821 552s [540] 17.251020 17.251020 6.560821 0.000000 0.000000 3.382287 12.605469 552s [547] 12.605469 0.000000 3.382287 15.892672 0.000000 0.000000 3.382287 552s [554] 0.000000 0.000000 0.000000 17.251020 17.251020 17.251020 12.605469 552s [561] 0.000000 15.892672 0.000000 3.382287 3.382287 12.605469 6.560821 552s [568] 12.605469 3.382287 3.382287 0.000000 17.251020 6.560821 15.892672 552s [575] 0.000000 9.671438 3.382287 3.382287 0.000000 12.605469 3.382287 552s [582] 12.605469 3.382287 0.000000 6.560821 0.000000 3.382287 17.251020 552s [589] 3.382287 12.605469 12.605469 17.251020 3.382287 9.671438 0.000000 552s [596] 17.251020 0.000000 6.560821 9.671438 9.671438 0.000000 0.000000 552s [603] 0.000000 12.605469 17.251020 12.605469 12.605469 6.560821 6.560821 552s [610] 15.892672 3.382287 6.560821 6.560821 9.671438 17.251020 17.251020 552s [617] 0.000000 3.382287 12.605469 15.892672 3.382287 0.000000 17.251020 552s [624] 12.605469 6.560821 17.251020 17.251020 0.000000 6.560821 15.892672 552s [631] 6.560821 6.560821 0.000000 15.892672 17.251020 0.000000 3.382287 552s [638] 17.251020 552s 552s $se.fit 552s [1] 0.1322852 0.2566014 0.4930147 0.4930147 0.6747076 0.0000000 0.0000000 552s [8] 0.2566014 0.6747076 0.1322852 0.6215810 0.1322852 0.0000000 0.3782613 552s [15] 0.6215810 0.6747076 0.4930147 0.6747076 0.1322852 0.6747076 0.6747076 552s [22] 0.3782613 0.1322852 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 552s [29] 0.0000000 0.6747076 0.0000000 0.3782613 0.4930147 0.1322852 0.1322852 552s [36] 0.0000000 0.0000000 0.4930147 0.0000000 0.4930147 0.0000000 0.6215810 552s [43] 0.4930147 0.6215810 0.1322852 0.6747076 0.6747076 0.2566014 0.1322852 552s [50] 0.0000000 0.3782613 0.6747076 0.6215810 0.0000000 0.1322852 0.6747076 552s [57] 0.2566014 0.6747076 0.0000000 0.1322852 0.4930147 0.4930147 0.0000000 552s [64] 0.0000000 0.6215810 0.6215810 0.0000000 0.4930147 0.6215810 0.1322852 552s [71] 0.6215810 0.2566014 0.1322852 0.6747076 0.4930147 0.0000000 0.4930147 552s [78] 0.4930147 0.1322852 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 552s [85] 0.1322852 0.2566014 0.1322852 0.0000000 0.1322852 0.6747076 0.2566014 552s [92] 0.1322852 0.6747076 0.3782613 0.1322852 0.0000000 0.1322852 0.1322852 552s [99] 0.4930147 0.0000000 0.1322852 0.1322852 0.4930147 0.0000000 0.0000000 552s [106] 0.6747076 0.0000000 0.2566014 0.6215810 0.6747076 0.1322852 0.6747076 552s [113] 0.1322852 0.0000000 0.0000000 0.1322852 0.2566014 0.0000000 0.2566014 552s [120] 0.1322852 0.0000000 0.0000000 0.2566014 0.6215810 0.4930147 0.4930147 552s [127] 0.0000000 0.6747076 0.0000000 0.6747076 0.1322852 0.0000000 0.4930147 552s [134] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.2566014 0.2566014 552s [141] 0.1322852 0.6747076 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 552s [148] 0.6747076 0.1322852 0.6215810 0.0000000 0.6747076 0.2566014 0.1322852 552s [155] 0.4930147 0.2566014 0.2566014 0.1322852 0.1322852 0.0000000 0.1322852 552s [162] 0.0000000 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.0000000 552s [169] 0.0000000 0.1322852 0.6747076 0.1322852 0.6747076 0.6215810 0.2566014 552s [176] 0.4930147 0.1322852 0.0000000 0.4930147 0.0000000 0.4930147 0.6747076 552s [183] 0.4930147 0.0000000 0.0000000 0.4930147 0.1322852 0.4930147 0.6747076 552s [190] 0.1322852 0.1322852 0.6747076 0.1322852 0.2566014 0.1322852 0.6747076 552s [197] 0.6747076 0.0000000 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 552s [204] 0.4930147 0.4930147 0.1322852 0.1322852 0.4930147 0.6747076 0.4930147 552s [211] 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.1322852 0.1322852 552s [218] 0.0000000 0.2566014 0.0000000 0.2566014 0.2566014 0.1322852 0.0000000 552s [225] 0.1322852 0.1322852 0.6747076 0.1322852 0.0000000 0.6747076 0.1322852 552s [232] 0.2566014 0.6747076 0.0000000 0.0000000 0.1322852 0.1322852 0.4930147 552s [239] 0.2566014 0.4930147 0.1322852 0.4930147 0.6747076 0.2566014 0.6747076 552s [246] 0.6747076 0.6215810 0.0000000 0.1322852 0.1322852 0.1322852 0.0000000 552s [253] 0.4930147 0.6215810 0.2566014 0.1322852 0.1322852 0.0000000 0.0000000 552s [260] 0.4930147 0.2566014 0.1322852 0.1322852 0.4930147 0.6747076 0.0000000 552s [267] 0.2566014 0.6215810 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 552s [274] 0.6747076 0.6215810 0.2566014 0.1322852 0.4930147 0.0000000 0.1322852 552s [281] 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.6215810 0.6747076 552s [288] 0.1322852 0.6747076 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 552s [295] 0.0000000 0.6747076 0.6747076 0.4930147 0.0000000 0.4930147 0.6747076 552s [302] 0.6215810 0.6215810 0.0000000 0.1322852 0.4930147 0.4930147 0.6215810 552s [309] 0.2566014 0.6215810 0.4930147 0.4930147 0.6747076 0.0000000 0.6747076 552s [316] 0.1322852 0.6747076 0.1322852 0.4930147 0.0000000 0.2566014 0.1322852 552s [323] 0.0000000 0.6215810 0.6747076 0.6747076 0.6747076 0.1322852 0.2566014 552s [330] 0.0000000 0.0000000 0.4930147 0.4930147 0.4930147 0.0000000 0.4930147 552s [337] 0.0000000 0.6215810 0.2566014 0.6747076 0.4930147 0.4930147 0.2566014 552s [344] 0.0000000 0.0000000 0.6747076 0.0000000 0.0000000 0.4930147 0.0000000 552s [351] 0.1322852 0.1322852 0.2566014 0.6747076 0.3782613 0.0000000 0.3782613 552s [358] 0.3782613 0.4930147 0.1322852 0.4930147 0.1322852 0.6747076 0.0000000 552s [365] 0.4930147 0.0000000 0.1322852 0.0000000 0.1322852 0.2566014 0.0000000 552s [372] 0.2566014 0.2566014 0.6747076 0.6215810 0.0000000 0.6747076 0.0000000 552s [379] 0.1322852 0.6747076 0.1322852 0.4930147 0.1322852 0.1322852 0.4930147 552s [386] 0.1322852 0.1322852 0.0000000 0.6215810 0.0000000 0.4930147 0.0000000 552s [393] 0.6215810 0.2566014 0.6215810 0.6215810 0.2566014 0.2566014 0.1322852 552s [400] 0.1322852 0.6747076 0.6747076 0.2566014 0.4930147 0.3782613 0.6215810 552s [407] 0.6747076 0.2566014 0.1322852 0.0000000 0.2566014 0.2566014 0.6215810 552s [414] 0.1322852 0.0000000 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 552s [421] 0.0000000 0.1322852 0.1322852 0.4930147 0.6747076 0.6747076 0.6747076 552s [428] 0.0000000 0.6215810 0.6747076 0.6747076 0.0000000 0.0000000 0.6747076 552s [435] 0.4930147 0.2566014 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 552s [442] 0.4930147 0.6747076 0.1322852 0.4930147 0.0000000 0.6747076 0.0000000 552s [449] 0.2566014 0.4930147 0.2566014 0.4930147 0.6215810 0.4930147 0.4930147 552s [456] 0.0000000 0.0000000 0.1322852 0.0000000 0.1322852 0.0000000 0.0000000 552s [463] 0.0000000 0.6747076 0.2566014 0.6747076 0.4930147 0.4930147 0.1322852 552s [470] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.0000000 0.0000000 552s [477] 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 0.1322852 0.4930147 552s [484] 0.2566014 0.6747076 0.3782613 0.6215810 0.6747076 0.6215810 0.0000000 552s [491] 0.0000000 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.4930147 552s [498] 0.4930147 0.4930147 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 552s [505] 0.2566014 0.1322852 0.6747076 0.1322852 0.4930147 0.4930147 0.6215810 552s [512] 0.0000000 0.4930147 0.6747076 0.2566014 0.0000000 0.1322852 0.0000000 552s [519] 0.6215810 0.0000000 0.4930147 0.4930147 0.0000000 0.6747076 0.0000000 552s [526] 0.3782613 0.0000000 0.1322852 0.6215810 0.1322852 0.1322852 0.1322852 552s [533] 0.6747076 0.6215810 0.0000000 0.0000000 0.0000000 0.6215810 0.2566014 552s [540] 0.6747076 0.6747076 0.2566014 0.0000000 0.0000000 0.1322852 0.4930147 552s [547] 0.4930147 0.0000000 0.1322852 0.6215810 0.0000000 0.0000000 0.1322852 552s [554] 0.0000000 0.0000000 0.0000000 0.6747076 0.6747076 0.6747076 0.4930147 552s [561] 0.0000000 0.6215810 0.0000000 0.1322852 0.1322852 0.4930147 0.2566014 552s [568] 0.4930147 0.1322852 0.1322852 0.0000000 0.6747076 0.2566014 0.6215810 552s [575] 0.0000000 0.3782613 0.1322852 0.1322852 0.0000000 0.4930147 0.1322852 552s [582] 0.4930147 0.1322852 0.0000000 0.2566014 0.0000000 0.1322852 0.6747076 552s [589] 0.1322852 0.4930147 0.4930147 0.6747076 0.1322852 0.3782613 0.0000000 552s [596] 0.6747076 0.0000000 0.2566014 0.3782613 0.3782613 0.0000000 0.0000000 552s [603] 0.0000000 0.4930147 0.6747076 0.4930147 0.4930147 0.2566014 0.2566014 552s [610] 0.6215810 0.1322852 0.2566014 0.2566014 0.3782613 0.6747076 0.6747076 552s [617] 0.0000000 0.1322852 0.4930147 0.6215810 0.1322852 0.0000000 0.6747076 552s [624] 0.4930147 0.2566014 0.6747076 0.6747076 0.0000000 0.2566014 0.6215810 552s [631] 0.2566014 0.2566014 0.0000000 0.6215810 0.6747076 0.0000000 0.1322852 552s [638] 0.6747076 552s 552s [1] 73.61884 552s [1] 4193.584 552s [1] 4193.584 552s Dose Response Model 552s 552s Model: linear 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -19.855 -3.996 -0.064 3.775 24.956 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -11.1996 0.811196 552s delta 0.0136 0.000532 552s age -0.0126 0.009027 552s centergreen 0.0191 0.793736 552s centerred 1.1979 0.810341 552s centersilver 0.7446 0.817870 552s centeryellow 1.2027 0.826882 552s 552s Residual standard error: 6.43 552s Degrees of freedom: 631 552s 552s Call: 552s lm(formula = y ~ x + age + center, data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -24.956 -3.775 0.064 3.996 19.855 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -1.120e+01 8.112e-01 -13.806 <2e-16 *** 552s x 1.360e-02 5.316e-04 25.575 <2e-16 *** 552s age -1.255e-02 9.027e-03 -1.391 0.165 552s centergreen 1.906e-02 7.937e-01 0.024 0.981 552s centerred 1.198e+00 8.103e-01 1.478 0.140 552s centersilver 7.446e-01 8.179e-01 0.910 0.363 552s centeryellow 1.203e+00 8.269e-01 1.455 0.146 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 6.427 on 631 degrees of freedom 552s Multiple R-squared: 0.5116, Adjusted R-squared: 0.507 552s F-statistic: 110.2 on 6 and 631 DF, p-value: < 2.2e-16 552s 552s e0 delta age centergreen 552s e0 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 552s delta -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 552s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 552s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 552s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 552s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 552s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 552s centerred centersilver centeryellow 552s e0 -3.460807e-01 -3.642369e-01 -3.253015e-01 552s delta -1.885394e-06 1.847581e-05 3.596102e-06 552s age 2.140485e-04 3.347250e-04 -2.387489e-04 552s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 552s centerred 6.566532e-01 3.366063e-01 3.351988e-01 552s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 552s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 552s (Intercept) x age centergreen 552s (Intercept) 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 552s x -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 552s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 552s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 552s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 552s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 552s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 552s centerred centersilver centeryellow 552s (Intercept) -3.460807e-01 -3.642369e-01 -3.253015e-01 552s x -1.885394e-06 1.847581e-05 3.596102e-06 552s age 2.140485e-04 3.347250e-04 -2.387489e-04 552s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 552s centerred 6.566532e-01 3.366063e-01 3.351988e-01 552s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 552s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 552s $fit 552s [1] 3.385405 6.566871 12.617093 12.617093 17.266927 0.000000 0.000000 552s [8] 6.566871 17.266927 3.385405 15.907326 3.385405 0.000000 9.680356 552s [15] 15.907326 17.266927 12.617093 17.266927 3.385405 17.266927 17.266927 552s [22] 9.680356 3.385405 12.617093 0.000000 12.617093 3.385405 6.566871 552s [29] 0.000000 17.266927 0.000000 9.680356 12.617093 3.385405 3.385405 552s [36] 0.000000 0.000000 12.617093 0.000000 12.617093 0.000000 15.907326 552s [43] 12.617093 15.907326 3.385405 17.266927 17.266927 6.566871 3.385405 552s [50] 0.000000 9.680356 17.266927 15.907326 0.000000 3.385405 17.266927 552s [57] 6.566871 17.266927 0.000000 3.385405 12.617093 12.617093 0.000000 552s [64] 0.000000 15.907326 15.907326 0.000000 12.617093 15.907326 3.385405 552s [71] 15.907326 6.566871 3.385405 17.266927 12.617093 0.000000 12.617093 552s [78] 12.617093 3.385405 0.000000 0.000000 0.000000 3.385405 3.385405 552s [85] 3.385405 6.566871 3.385405 0.000000 3.385405 17.266927 6.566871 552s [92] 3.385405 17.266927 9.680356 3.385405 0.000000 3.385405 3.385405 552s [99] 12.617093 0.000000 3.385405 3.385405 12.617093 0.000000 0.000000 552s [106] 17.266927 0.000000 6.566871 15.907326 17.266927 3.385405 17.266927 552s [113] 3.385405 0.000000 0.000000 3.385405 6.566871 0.000000 6.566871 552s [120] 3.385405 0.000000 0.000000 6.566871 15.907326 12.617093 12.617093 552s [127] 0.000000 17.266927 0.000000 17.266927 3.385405 0.000000 12.617093 552s [134] 17.266927 0.000000 3.385405 0.000000 6.566871 6.566871 6.566871 552s [141] 3.385405 17.266927 0.000000 0.000000 3.385405 0.000000 15.907326 552s [148] 17.266927 3.385405 15.907326 0.000000 17.266927 6.566871 3.385405 552s [155] 12.617093 6.566871 6.566871 3.385405 3.385405 0.000000 3.385405 552s [162] 0.000000 3.385405 12.617093 3.385405 0.000000 17.266927 0.000000 552s [169] 0.000000 3.385405 17.266927 3.385405 17.266927 15.907326 6.566871 552s [176] 12.617093 3.385405 0.000000 12.617093 0.000000 12.617093 17.266927 552s [183] 12.617093 0.000000 0.000000 12.617093 3.385405 12.617093 17.266927 552s [190] 3.385405 3.385405 17.266927 3.385405 6.566871 3.385405 17.266927 552s [197] 17.266927 0.000000 12.617093 0.000000 12.617093 3.385405 6.566871 552s [204] 12.617093 12.617093 3.385405 3.385405 12.617093 17.266927 12.617093 552s [211] 3.385405 3.385405 17.266927 0.000000 6.566871 3.385405 3.385405 552s [218] 0.000000 6.566871 0.000000 6.566871 6.566871 3.385405 0.000000 552s [225] 3.385405 3.385405 17.266927 3.385405 0.000000 17.266927 3.385405 552s [232] 6.566871 17.266927 0.000000 0.000000 3.385405 3.385405 12.617093 552s [239] 6.566871 12.617093 3.385405 12.617093 17.266927 6.566871 17.266927 552s [246] 17.266927 15.907326 0.000000 3.385405 3.385405 3.385405 0.000000 552s [253] 12.617093 15.907326 6.566871 3.385405 3.385405 0.000000 0.000000 552s [260] 12.617093 6.566871 3.385405 3.385405 12.617093 17.266927 0.000000 552s [267] 6.566871 15.907326 3.385405 15.907326 3.385405 12.617093 0.000000 552s [274] 17.266927 15.907326 6.566871 3.385405 12.617093 0.000000 3.385405 552s [281] 3.385405 12.617093 3.385405 0.000000 17.266927 15.907326 17.266927 552s [288] 3.385405 17.266927 3.385405 3.385405 3.385405 15.907326 0.000000 552s [295] 0.000000 17.266927 17.266927 12.617093 0.000000 12.617093 17.266927 552s [302] 15.907326 15.907326 0.000000 3.385405 12.617093 12.617093 15.907326 552s [309] 6.566871 15.907326 12.617093 12.617093 17.266927 0.000000 17.266927 552s [316] 3.385405 17.266927 3.385405 12.617093 0.000000 6.566871 3.385405 552s [323] 0.000000 15.907326 17.266927 17.266927 17.266927 3.385405 6.566871 552s [330] 0.000000 0.000000 12.617093 12.617093 12.617093 0.000000 12.617093 552s [337] 0.000000 15.907326 6.566871 17.266927 12.617093 12.617093 6.566871 552s [344] 0.000000 0.000000 17.266927 0.000000 0.000000 12.617093 0.000000 552s [351] 3.385405 3.385405 6.566871 17.266927 9.680356 0.000000 9.680356 552s [358] 9.680356 12.617093 3.385405 12.617093 3.385405 17.266927 0.000000 552s [365] 12.617093 0.000000 3.385405 0.000000 3.385405 6.566871 0.000000 552s [372] 6.566871 6.566871 17.266927 15.907326 0.000000 17.266927 0.000000 552s [379] 3.385405 17.266927 3.385405 12.617093 3.385405 3.385405 12.617093 552s [386] 3.385405 3.385405 0.000000 15.907326 0.000000 12.617093 0.000000 552s [393] 15.907326 6.566871 15.907326 15.907326 6.566871 6.566871 3.385405 552s [400] 3.385405 17.266927 17.266927 6.566871 12.617093 9.680356 15.907326 552s [407] 17.266927 6.566871 3.385405 0.000000 6.566871 6.566871 15.907326 552s [414] 3.385405 0.000000 0.000000 0.000000 0.000000 3.385405 3.385405 552s [421] 0.000000 3.385405 3.385405 12.617093 17.266927 17.266927 17.266927 552s [428] 0.000000 15.907326 17.266927 17.266927 0.000000 0.000000 17.266927 552s [435] 12.617093 6.566871 0.000000 0.000000 3.385405 0.000000 15.907326 552s [442] 12.617093 17.266927 3.385405 12.617093 0.000000 17.266927 0.000000 552s [449] 6.566871 12.617093 6.566871 12.617093 15.907326 12.617093 12.617093 552s [456] 0.000000 0.000000 3.385405 0.000000 3.385405 0.000000 0.000000 552s [463] 0.000000 17.266927 6.566871 17.266927 12.617093 12.617093 3.385405 552s [470] 17.266927 0.000000 3.385405 0.000000 6.566871 0.000000 0.000000 552s [477] 3.385405 15.907326 3.385405 12.617093 0.000000 3.385405 12.617093 552s [484] 6.566871 17.266927 9.680356 15.907326 17.266927 15.907326 0.000000 552s [491] 0.000000 3.385405 3.385405 17.266927 0.000000 6.566871 12.617093 552s [498] 12.617093 12.617093 3.385405 3.385405 3.385405 15.907326 0.000000 552s [505] 6.566871 3.385405 17.266927 3.385405 12.617093 12.617093 15.907326 552s [512] 0.000000 12.617093 17.266927 6.566871 0.000000 3.385405 0.000000 552s [519] 15.907326 0.000000 12.617093 12.617093 0.000000 17.266927 0.000000 552s [526] 9.680356 0.000000 3.385405 15.907326 3.385405 3.385405 3.385405 552s [533] 17.266927 15.907326 0.000000 0.000000 0.000000 15.907326 6.566871 552s [540] 17.266927 17.266927 6.566871 0.000000 0.000000 3.385405 12.617093 552s [547] 12.617093 0.000000 3.385405 15.907326 0.000000 0.000000 3.385405 552s [554] 0.000000 0.000000 0.000000 17.266927 17.266927 17.266927 12.617093 552s [561] 0.000000 15.907326 0.000000 3.385405 3.385405 12.617093 6.566871 552s [568] 12.617093 3.385405 3.385405 0.000000 17.266927 6.566871 15.907326 552s [575] 0.000000 9.680356 3.385405 3.385405 0.000000 12.617093 3.385405 552s [582] 12.617093 3.385405 0.000000 6.566871 0.000000 3.385405 17.266927 552s [589] 3.385405 12.617093 12.617093 17.266927 3.385405 9.680356 0.000000 552s [596] 17.266927 0.000000 6.566871 9.680356 9.680356 0.000000 0.000000 552s [603] 0.000000 12.617093 17.266927 12.617093 12.617093 6.566871 6.566871 552s [610] 15.907326 3.385405 6.566871 6.566871 9.680356 17.266927 17.266927 552s [617] 0.000000 3.385405 12.617093 15.907326 3.385405 0.000000 17.266927 552s [624] 12.617093 6.566871 17.266927 17.266927 0.000000 6.566871 15.907326 552s [631] 6.566871 6.566871 0.000000 15.907326 17.266927 0.000000 3.385405 552s [638] 17.266927 552s 552s $se.fit 552s [1] 0.1323718 0.2567693 0.4933373 0.4933373 0.6751491 0.0000000 0.0000000 552s [8] 0.2567693 0.6751491 0.1323718 0.6219878 0.1323718 0.0000000 0.3785088 552s [15] 0.6219878 0.6751491 0.4933373 0.6751491 0.1323718 0.6751491 0.6751491 552s [22] 0.3785088 0.1323718 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 552s [29] 0.0000000 0.6751491 0.0000000 0.3785088 0.4933373 0.1323718 0.1323718 552s [36] 0.0000000 0.0000000 0.4933373 0.0000000 0.4933373 0.0000000 0.6219878 552s [43] 0.4933373 0.6219878 0.1323718 0.6751491 0.6751491 0.2567693 0.1323718 552s [50] 0.0000000 0.3785088 0.6751491 0.6219878 0.0000000 0.1323718 0.6751491 552s [57] 0.2567693 0.6751491 0.0000000 0.1323718 0.4933373 0.4933373 0.0000000 552s [64] 0.0000000 0.6219878 0.6219878 0.0000000 0.4933373 0.6219878 0.1323718 552s [71] 0.6219878 0.2567693 0.1323718 0.6751491 0.4933373 0.0000000 0.4933373 552s [78] 0.4933373 0.1323718 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 552s [85] 0.1323718 0.2567693 0.1323718 0.0000000 0.1323718 0.6751491 0.2567693 552s [92] 0.1323718 0.6751491 0.3785088 0.1323718 0.0000000 0.1323718 0.1323718 552s [99] 0.4933373 0.0000000 0.1323718 0.1323718 0.4933373 0.0000000 0.0000000 552s [106] 0.6751491 0.0000000 0.2567693 0.6219878 0.6751491 0.1323718 0.6751491 552s [113] 0.1323718 0.0000000 0.0000000 0.1323718 0.2567693 0.0000000 0.2567693 552s [120] 0.1323718 0.0000000 0.0000000 0.2567693 0.6219878 0.4933373 0.4933373 552s [127] 0.0000000 0.6751491 0.0000000 0.6751491 0.1323718 0.0000000 0.4933373 552s [134] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.2567693 0.2567693 552s [141] 0.1323718 0.6751491 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 552s [148] 0.6751491 0.1323718 0.6219878 0.0000000 0.6751491 0.2567693 0.1323718 552s [155] 0.4933373 0.2567693 0.2567693 0.1323718 0.1323718 0.0000000 0.1323718 552s [162] 0.0000000 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.0000000 552s [169] 0.0000000 0.1323718 0.6751491 0.1323718 0.6751491 0.6219878 0.2567693 552s [176] 0.4933373 0.1323718 0.0000000 0.4933373 0.0000000 0.4933373 0.6751491 552s [183] 0.4933373 0.0000000 0.0000000 0.4933373 0.1323718 0.4933373 0.6751491 552s [190] 0.1323718 0.1323718 0.6751491 0.1323718 0.2567693 0.1323718 0.6751491 552s [197] 0.6751491 0.0000000 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 552s [204] 0.4933373 0.4933373 0.1323718 0.1323718 0.4933373 0.6751491 0.4933373 552s [211] 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.1323718 0.1323718 552s [218] 0.0000000 0.2567693 0.0000000 0.2567693 0.2567693 0.1323718 0.0000000 552s [225] 0.1323718 0.1323718 0.6751491 0.1323718 0.0000000 0.6751491 0.1323718 552s [232] 0.2567693 0.6751491 0.0000000 0.0000000 0.1323718 0.1323718 0.4933373 552s [239] 0.2567693 0.4933373 0.1323718 0.4933373 0.6751491 0.2567693 0.6751491 552s [246] 0.6751491 0.6219878 0.0000000 0.1323718 0.1323718 0.1323718 0.0000000 552s [253] 0.4933373 0.6219878 0.2567693 0.1323718 0.1323718 0.0000000 0.0000000 552s [260] 0.4933373 0.2567693 0.1323718 0.1323718 0.4933373 0.6751491 0.0000000 552s [267] 0.2567693 0.6219878 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 552s [274] 0.6751491 0.6219878 0.2567693 0.1323718 0.4933373 0.0000000 0.1323718 552s [281] 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.6219878 0.6751491 552s [288] 0.1323718 0.6751491 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 552s [295] 0.0000000 0.6751491 0.6751491 0.4933373 0.0000000 0.4933373 0.6751491 552s [302] 0.6219878 0.6219878 0.0000000 0.1323718 0.4933373 0.4933373 0.6219878 552s [309] 0.2567693 0.6219878 0.4933373 0.4933373 0.6751491 0.0000000 0.6751491 552s [316] 0.1323718 0.6751491 0.1323718 0.4933373 0.0000000 0.2567693 0.1323718 552s [323] 0.0000000 0.6219878 0.6751491 0.6751491 0.6751491 0.1323718 0.2567693 552s [330] 0.0000000 0.0000000 0.4933373 0.4933373 0.4933373 0.0000000 0.4933373 552s [337] 0.0000000 0.6219878 0.2567693 0.6751491 0.4933373 0.4933373 0.2567693 552s [344] 0.0000000 0.0000000 0.6751491 0.0000000 0.0000000 0.4933373 0.0000000 552s [351] 0.1323718 0.1323718 0.2567693 0.6751491 0.3785088 0.0000000 0.3785088 552s [358] 0.3785088 0.4933373 0.1323718 0.4933373 0.1323718 0.6751491 0.0000000 552s [365] 0.4933373 0.0000000 0.1323718 0.0000000 0.1323718 0.2567693 0.0000000 552s [372] 0.2567693 0.2567693 0.6751491 0.6219878 0.0000000 0.6751491 0.0000000 552s [379] 0.1323718 0.6751491 0.1323718 0.4933373 0.1323718 0.1323718 0.4933373 552s [386] 0.1323718 0.1323718 0.0000000 0.6219878 0.0000000 0.4933373 0.0000000 552s [393] 0.6219878 0.2567693 0.6219878 0.6219878 0.2567693 0.2567693 0.1323718 552s [400] 0.1323718 0.6751491 0.6751491 0.2567693 0.4933373 0.3785088 0.6219878 552s [407] 0.6751491 0.2567693 0.1323718 0.0000000 0.2567693 0.2567693 0.6219878 552s [414] 0.1323718 0.0000000 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 552s [421] 0.0000000 0.1323718 0.1323718 0.4933373 0.6751491 0.6751491 0.6751491 552s [428] 0.0000000 0.6219878 0.6751491 0.6751491 0.0000000 0.0000000 0.6751491 552s [435] 0.4933373 0.2567693 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 552s [442] 0.4933373 0.6751491 0.1323718 0.4933373 0.0000000 0.6751491 0.0000000 552s [449] 0.2567693 0.4933373 0.2567693 0.4933373 0.6219878 0.4933373 0.4933373 552s [456] 0.0000000 0.0000000 0.1323718 0.0000000 0.1323718 0.0000000 0.0000000 552s [463] 0.0000000 0.6751491 0.2567693 0.6751491 0.4933373 0.4933373 0.1323718 552s [470] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.0000000 0.0000000 552s [477] 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 0.1323718 0.4933373 552s [484] 0.2567693 0.6751491 0.3785088 0.6219878 0.6751491 0.6219878 0.0000000 552s [491] 0.0000000 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.4933373 552s [498] 0.4933373 0.4933373 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 552s [505] 0.2567693 0.1323718 0.6751491 0.1323718 0.4933373 0.4933373 0.6219878 552s [512] 0.0000000 0.4933373 0.6751491 0.2567693 0.0000000 0.1323718 0.0000000 552s [519] 0.6219878 0.0000000 0.4933373 0.4933373 0.0000000 0.6751491 0.0000000 552s [526] 0.3785088 0.0000000 0.1323718 0.6219878 0.1323718 0.1323718 0.1323718 552s [533] 0.6751491 0.6219878 0.0000000 0.0000000 0.0000000 0.6219878 0.2567693 552s [540] 0.6751491 0.6751491 0.2567693 0.0000000 0.0000000 0.1323718 0.4933373 552s [547] 0.4933373 0.0000000 0.1323718 0.6219878 0.0000000 0.0000000 0.1323718 552s [554] 0.0000000 0.0000000 0.0000000 0.6751491 0.6751491 0.6751491 0.4933373 552s [561] 0.0000000 0.6219878 0.0000000 0.1323718 0.1323718 0.4933373 0.2567693 552s [568] 0.4933373 0.1323718 0.1323718 0.0000000 0.6751491 0.2567693 0.6219878 552s [575] 0.0000000 0.3785088 0.1323718 0.1323718 0.0000000 0.4933373 0.1323718 552s [582] 0.4933373 0.1323718 0.0000000 0.2567693 0.0000000 0.1323718 0.6751491 552s [589] 0.1323718 0.4933373 0.4933373 0.6751491 0.1323718 0.3785088 0.0000000 552s [596] 0.6751491 0.0000000 0.2567693 0.3785088 0.3785088 0.0000000 0.0000000 552s [603] 0.0000000 0.4933373 0.6751491 0.4933373 0.4933373 0.2567693 0.2567693 552s [610] 0.6219878 0.1323718 0.2567693 0.2567693 0.3785088 0.6751491 0.6751491 552s [617] 0.0000000 0.1323718 0.4933373 0.6219878 0.1323718 0.0000000 0.6751491 552s [624] 0.4933373 0.2567693 0.6751491 0.6751491 0.0000000 0.2567693 0.6219878 552s [631] 0.2567693 0.2567693 0.0000000 0.6219878 0.6751491 0.0000000 0.1323718 552s [638] 0.6751491 552s 552s $fit 552s [1] -11.57621 -11.56261 -11.54901 -10.21661 552s 552s $se.fit 552s [1] 0.6876991 0.6874618 0.6872248 0.6656515 552s 552s $fit 552s 1 2 3 4 552s -11.57621 -11.56261 -11.54901 -10.21661 552s 552s $se.fit 552s 1 2 3 4 552s 0.6876991 0.6874618 0.6872248 0.6656515 552s 552s $df 552s [1] 631 552s 552s $residual.scale 552s [1] 6.427248 552s 552s [1] 73.55102 552s [1] 2768.739 552s [1] 2768.739 552s Dose Response Model 552s 552s Model: linlog 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -18.804 -3.875 -0.163 4.453 17.258 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -13.65 2.626 552s delta 2.21 0.402 552s 552s Residual standard error: 6.12 552s Degrees of freedom: 426 552s 552s Call: 552s lm(formula = y ~ log(x + off), data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -17.2582 -4.4526 0.1627 3.8749 18.8035 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -13.6486 2.6260 -5.197 3.14e-07 *** 552s log(x + off) 2.2117 0.4016 5.508 6.29e-08 *** 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 6.116 on 426 degrees of freedom 552s Multiple R-squared: 0.06648, Adjusted R-squared: 0.06429 552s F-statistic: 30.34 on 1 and 426 DF, p-value: 6.29e-08 552s 552s e0 delta 552s e0 6.896082 -1.0477868 552s delta -1.047787 0.1612436 552s (Intercept) log(x + off) 552s (Intercept) 6.896082 -1.0477868 552s log(x + off) -1.047787 0.1612436 552s $fit 552s [1] 6.008369 5.658359 0.000000 4.514640 4.877164 4.115493 6.008369 6.641510 552s [9] 0.000000 4.115493 5.658359 6.247655 4.514640 6.247655 4.514640 4.514640 552s [17] 4.115493 0.000000 6.008369 4.877164 4.877164 6.247655 6.733679 6.247655 552s [25] 4.115493 4.877164 0.000000 6.733679 6.641510 4.514640 4.514640 5.658359 552s [33] 6.008369 4.877164 4.877164 0.000000 6.008369 6.733679 4.877164 6.008369 552s [41] 6.733679 4.877164 6.008369 6.008369 4.877164 5.658359 4.514640 4.877164 552s [49] 0.000000 4.514640 5.658359 0.000000 4.877164 6.733679 4.877164 4.514640 552s [57] 4.877164 5.658359 6.641510 4.877164 6.733679 5.658359 0.000000 6.247655 552s [65] 6.247655 5.658359 4.877164 4.877164 4.115493 4.877164 6.733679 6.247655 552s [73] 5.658359 5.658359 4.877164 5.535104 6.008369 5.535104 6.247655 6.008369 552s [81] 6.247655 6.008369 5.535104 4.115493 5.658359 4.877164 6.008369 4.877164 552s [89] 6.247655 0.000000 6.008369 4.514640 4.514640 6.008369 4.877164 5.658359 552s [97] 4.877164 6.008369 6.733679 5.658359 4.115493 6.247655 0.000000 6.008369 552s [105] 6.247655 4.877164 6.733679 5.658359 4.115493 5.658359 5.658359 5.658359 552s [113] 6.008369 6.008369 6.733679 4.115493 4.877164 4.115493 4.877164 5.658359 552s [121] 4.514640 6.247655 4.877164 6.641510 4.115493 4.877164 5.658359 4.877164 552s [129] 4.514640 0.000000 6.008369 4.514640 6.733679 4.877164 4.514640 4.877164 552s [137] 5.658359 5.658359 4.115493 6.247655 6.641510 4.877164 5.658359 4.514640 552s [145] 4.115493 4.115493 6.733679 4.877164 0.000000 4.877164 5.658359 4.514640 552s [153] 6.641510 4.514640 4.877164 4.115493 6.247655 4.115493 6.008369 4.877164 552s [161] 4.514640 4.115493 4.877164 6.733679 6.247655 4.514640 4.877164 5.658359 552s [169] 4.115493 0.000000 5.658359 5.658359 4.877164 4.514640 4.115493 4.877164 552s [177] 0.000000 5.658359 6.247655 6.733679 0.000000 6.008369 4.514640 4.877164 552s [185] 0.000000 6.733679 5.658359 6.247655 4.514640 5.535104 5.658359 4.877164 552s [193] 5.658359 6.733679 6.641510 4.514640 6.008369 4.115493 4.877164 4.877164 552s [201] 4.115493 6.247655 5.658359 6.247655 5.535104 0.000000 4.115493 6.641510 552s [209] 6.247655 6.008369 4.115493 4.514640 4.514640 6.641510 6.733679 6.733679 552s [217] 5.658359 5.658359 6.008369 4.115493 5.658359 6.641510 6.641510 4.877164 552s [225] 0.000000 4.877164 0.000000 4.115493 4.877164 5.535104 4.115493 5.658359 552s [233] 6.733679 4.514640 6.733679 4.514640 4.514640 5.658359 6.008369 5.658359 552s [241] 4.877164 4.514640 4.115493 4.115493 4.115493 6.247655 5.658359 0.000000 552s [249] 4.115493 4.514640 6.247655 6.733679 6.008369 4.877164 4.115493 4.514640 552s [257] 0.000000 0.000000 5.658359 5.658359 4.514640 5.658359 4.514640 4.115493 552s [265] 4.877164 4.877164 4.514640 5.658359 6.008369 4.514640 4.115493 0.000000 552s [273] 4.877164 4.877164 4.115493 6.008369 4.514640 6.008369 4.514640 4.877164 552s [281] 6.008369 0.000000 0.000000 5.658359 6.247655 6.008369 6.008369 6.247655 552s [289] 4.877164 4.877164 4.514640 6.008369 6.008369 4.115493 6.641510 6.733679 552s [297] 4.514640 4.877164 4.877164 4.877164 6.008369 6.641510 4.877164 5.658359 552s [305] 4.514640 5.535104 4.877164 6.008369 6.008369 5.658359 4.514640 6.008369 552s [313] 6.247655 5.658359 6.733679 6.008369 6.247655 5.658359 5.535104 4.877164 552s [321] 5.658359 4.877164 4.877164 5.658359 5.658359 4.877164 4.115493 4.877164 552s [329] 5.658359 4.877164 4.877164 4.877164 5.658359 6.733679 6.008369 6.247655 552s [337] 4.877164 5.535104 6.008369 4.115493 6.008369 6.247655 4.115493 6.008369 552s [345] 5.658359 4.877164 6.247655 6.641510 5.658359 4.115493 6.733679 6.008369 552s [353] 5.658359 4.115493 4.514640 4.877164 6.733679 5.658359 0.000000 6.641510 552s [361] 6.733679 4.115493 6.247655 4.877164 4.877164 5.658359 4.514640 4.115493 552s [369] 4.877164 4.877164 4.877164 5.658359 4.877164 0.000000 5.658359 4.877164 552s [377] 4.877164 4.514640 4.514640 6.733679 6.008369 6.733679 4.514640 4.514640 552s [385] 4.115493 5.535104 4.877164 4.877164 6.247655 5.658359 6.733679 4.514640 552s [393] 4.877164 5.658359 6.733679 6.733679 4.514640 6.008369 5.658359 6.733679 552s [401] 6.733679 6.733679 0.000000 6.641510 6.733679 4.115493 4.877164 6.247655 552s [409] 0.000000 4.115493 4.514640 4.877164 4.877164 4.514640 6.733679 6.247655 552s [417] 5.658359 4.877164 4.877164 0.000000 4.877164 4.877164 0.000000 6.008369 552s [425] 4.115493 4.514640 4.877164 0.000000 552s 552s $se.fit 552s [1] 1.0908488 1.0273028 0.0000000 0.8196550 0.8854731 0.7471878 1.0908488 552s [8] 1.2057987 0.0000000 0.7471878 1.0273028 1.1342924 0.8196550 1.1342924 552s [15] 0.8196550 0.8196550 0.7471878 0.0000000 1.0908488 0.8854731 0.8854731 552s [22] 1.1342924 1.2225325 1.1342924 0.7471878 0.8854731 0.0000000 1.2225325 552s [29] 1.2057987 0.8196550 0.8196550 1.0273028 1.0908488 0.8854731 0.8854731 552s [36] 0.0000000 1.0908488 1.2225325 0.8854731 1.0908488 1.2225325 0.8854731 552s [43] 1.0908488 1.0908488 0.8854731 1.0273028 0.8196550 0.8854731 0.0000000 552s [50] 0.8196550 1.0273028 0.0000000 0.8854731 1.2225325 0.8854731 0.8196550 552s [57] 0.8854731 1.0273028 1.2057987 0.8854731 1.2225325 1.0273028 0.0000000 552s [64] 1.1342924 1.1342924 1.0273028 0.8854731 0.8854731 0.7471878 0.8854731 552s [71] 1.2225325 1.1342924 1.0273028 1.0273028 0.8854731 1.0049252 1.0908488 552s [78] 1.0049252 1.1342924 1.0908488 1.1342924 1.0908488 1.0049252 0.7471878 552s [85] 1.0273028 0.8854731 1.0908488 0.8854731 1.1342924 0.0000000 1.0908488 552s [92] 0.8196550 0.8196550 1.0908488 0.8854731 1.0273028 0.8854731 1.0908488 552s [99] 1.2225325 1.0273028 0.7471878 1.1342924 0.0000000 1.0908488 1.1342924 552s [106] 0.8854731 1.2225325 1.0273028 0.7471878 1.0273028 1.0273028 1.0273028 552s [113] 1.0908488 1.0908488 1.2225325 0.7471878 0.8854731 0.7471878 0.8854731 552s [120] 1.0273028 0.8196550 1.1342924 0.8854731 1.2057987 0.7471878 0.8854731 552s [127] 1.0273028 0.8854731 0.8196550 0.0000000 1.0908488 0.8196550 1.2225325 552s [134] 0.8854731 0.8196550 0.8854731 1.0273028 1.0273028 0.7471878 1.1342924 552s [141] 1.2057987 0.8854731 1.0273028 0.8196550 0.7471878 0.7471878 1.2225325 552s [148] 0.8854731 0.0000000 0.8854731 1.0273028 0.8196550 1.2057987 0.8196550 552s [155] 0.8854731 0.7471878 1.1342924 0.7471878 1.0908488 0.8854731 0.8196550 552s [162] 0.7471878 0.8854731 1.2225325 1.1342924 0.8196550 0.8854731 1.0273028 552s [169] 0.7471878 0.0000000 1.0273028 1.0273028 0.8854731 0.8196550 0.7471878 552s [176] 0.8854731 0.0000000 1.0273028 1.1342924 1.2225325 0.0000000 1.0908488 552s [183] 0.8196550 0.8854731 0.0000000 1.2225325 1.0273028 1.1342924 0.8196550 552s [190] 1.0049252 1.0273028 0.8854731 1.0273028 1.2225325 1.2057987 0.8196550 552s [197] 1.0908488 0.7471878 0.8854731 0.8854731 0.7471878 1.1342924 1.0273028 552s [204] 1.1342924 1.0049252 0.0000000 0.7471878 1.2057987 1.1342924 1.0908488 552s [211] 0.7471878 0.8196550 0.8196550 1.2057987 1.2225325 1.2225325 1.0273028 552s [218] 1.0273028 1.0908488 0.7471878 1.0273028 1.2057987 1.2057987 0.8854731 552s [225] 0.0000000 0.8854731 0.0000000 0.7471878 0.8854731 1.0049252 0.7471878 552s [232] 1.0273028 1.2225325 0.8196550 1.2225325 0.8196550 0.8196550 1.0273028 552s [239] 1.0908488 1.0273028 0.8854731 0.8196550 0.7471878 0.7471878 0.7471878 552s [246] 1.1342924 1.0273028 0.0000000 0.7471878 0.8196550 1.1342924 1.2225325 552s [253] 1.0908488 0.8854731 0.7471878 0.8196550 0.0000000 0.0000000 1.0273028 552s [260] 1.0273028 0.8196550 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 552s [267] 0.8196550 1.0273028 1.0908488 0.8196550 0.7471878 0.0000000 0.8854731 552s [274] 0.8854731 0.7471878 1.0908488 0.8196550 1.0908488 0.8196550 0.8854731 552s [281] 1.0908488 0.0000000 0.0000000 1.0273028 1.1342924 1.0908488 1.0908488 552s [288] 1.1342924 0.8854731 0.8854731 0.8196550 1.0908488 1.0908488 0.7471878 552s [295] 1.2057987 1.2225325 0.8196550 0.8854731 0.8854731 0.8854731 1.0908488 552s [302] 1.2057987 0.8854731 1.0273028 0.8196550 1.0049252 0.8854731 1.0908488 552s [309] 1.0908488 1.0273028 0.8196550 1.0908488 1.1342924 1.0273028 1.2225325 552s [316] 1.0908488 1.1342924 1.0273028 1.0049252 0.8854731 1.0273028 0.8854731 552s [323] 0.8854731 1.0273028 1.0273028 0.8854731 0.7471878 0.8854731 1.0273028 552s [330] 0.8854731 0.8854731 0.8854731 1.0273028 1.2225325 1.0908488 1.1342924 552s [337] 0.8854731 1.0049252 1.0908488 0.7471878 1.0908488 1.1342924 0.7471878 552s [344] 1.0908488 1.0273028 0.8854731 1.1342924 1.2057987 1.0273028 0.7471878 552s [351] 1.2225325 1.0908488 1.0273028 0.7471878 0.8196550 0.8854731 1.2225325 552s [358] 1.0273028 0.0000000 1.2057987 1.2225325 0.7471878 1.1342924 0.8854731 552s [365] 0.8854731 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 0.8854731 552s [372] 1.0273028 0.8854731 0.0000000 1.0273028 0.8854731 0.8854731 0.8196550 552s [379] 0.8196550 1.2225325 1.0908488 1.2225325 0.8196550 0.8196550 0.7471878 552s [386] 1.0049252 0.8854731 0.8854731 1.1342924 1.0273028 1.2225325 0.8196550 552s [393] 0.8854731 1.0273028 1.2225325 1.2225325 0.8196550 1.0908488 1.0273028 552s [400] 1.2225325 1.2225325 1.2225325 0.0000000 1.2057987 1.2225325 0.7471878 552s [407] 0.8854731 1.1342924 0.0000000 0.7471878 0.8196550 0.8854731 0.8854731 552s [414] 0.8196550 1.2225325 1.1342924 1.0273028 0.8854731 0.8854731 0.0000000 552s [421] 0.8854731 0.8854731 0.0000000 1.0908488 0.7471878 0.8196550 0.8854731 552s [428] 0.0000000 552s 552s [1] 40.01633 552s [1] 2773.961 552s [1] 2773.961 552s Dose Response Model 552s 552s Model: linlog 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -17.993 -3.920 -0.142 4.548 17.772 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -12.53812 2.7627 552s delta 2.19176 0.4045 552s age -0.00815 0.0103 552s centergreen -0.11764 0.9231 552s centerred -1.68381 0.9385 552s centersilver -0.40779 0.9137 552s centeryellow -0.83235 0.9332 552s 552s Residual standard error: 6.12 552s Degrees of freedom: 421 552s 552s Call: 552s lm(formula = y ~ log(x + off) + age + center, data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -17.7720 -4.5476 0.1417 3.9205 17.9926 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -12.538125 2.762741 -4.538 7.41e-06 *** 552s log(x + off) 2.191761 0.404501 5.418 1.01e-07 *** 552s age -0.008153 0.010337 -0.789 0.4308 552s centergreen -0.117636 0.923131 -0.127 0.8987 552s centerred -1.683810 0.938487 -1.794 0.0735 . 552s centersilver -0.407788 0.913735 -0.446 0.6556 552s centeryellow -0.832351 0.933224 -0.892 0.3730 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 6.118 on 421 degrees of freedom 552s Multiple R-squared: 0.07685, Adjusted R-squared: 0.06369 552s F-statistic: 5.841 on 6 and 421 DF, p-value: 7.284e-06 552s 552s e0 delta age centergreen 552s e0 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 552s delta -1.065954459 0.1636213662 0.0003614495 -0.0285500750 552s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 552s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 552s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 552s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 552s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 552s centerred centersilver centeryellow 552s e0 -0.3271697994 -0.3433662837 -0.3049047728 552s delta -0.0143714026 -0.0139200933 -0.0188552161 552s age 0.0001539174 0.0004143178 0.0002799329 552s centergreen 0.4142785346 0.4148464502 0.4153997441 552s centerred 0.8807582409 0.4133097826 0.4135270947 552s centersilver 0.4133097826 0.8349108233 0.4142615949 552s centeryellow 0.4135270947 0.4142615949 0.8709075166 552s (Intercept) log(x + off) age centergreen 552s (Intercept) 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 552s log(x + off) -1.065954459 0.1636213662 0.0003614495 -0.0285500750 552s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 552s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 552s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 552s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 552s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 552s centerred centersilver centeryellow 552s (Intercept) -0.3271697994 -0.3433662837 -0.3049047728 552s log(x + off) -0.0143714026 -0.0139200933 -0.0188552161 552s age 0.0001539174 0.0004143178 0.0002799329 552s centergreen 0.4142785346 0.4148464502 0.4153997441 552s centerred 0.8807582409 0.4133097826 0.4135270947 552s centersilver 0.4133097826 0.8349108233 0.4142615949 552s centeryellow 0.4135270947 0.4142615949 0.8709075166 552s $fit 552s [1] -3.511779 -3.480690 -3.450035 -1.567022 552s 552s $se.fit 552s [1] 1.1058048 1.1012159 1.0967017 0.8461873 552s 552s $fit 552s 1 2 3 4 552s -3.511779 -3.480690 -3.450035 -1.567022 552s 552s $se.fit 552s 1 2 3 4 552s 1.1058048 1.1012159 1.0967017 0.8461873 552s 552s $df 552s [1] 421 552s 552s $residual.scale 552s [1] 6.117927 552s 552s [1] 40.47058 552s [1] 54.33574 552s [1] 54.33574 552s Dose Response Model 552s 552s Model: quadratic 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -9.08e-01 -3.06e-01 3.08e-05 2.39e-01 7.57e-01 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -3.12e+00 9.19e-02 552s b1 -6.61e-04 1.47e-03 552s b2 5.18e-06 4.40e-06 552s 552s Residual standard error: 0.401 552s Degrees of freedom: 46 552s 552s Call: 552s lm(formula = y ~ x + I(x^2), data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -0.75741 -0.23947 -0.00003 0.30638 0.90831 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -3.118e+00 9.195e-02 -33.914 <2e-16 *** 552s x -6.612e-04 1.466e-03 -0.451 0.654 552s I(x^2) 5.175e-06 4.401e-06 1.176 0.246 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.4007 on 46 degrees of freedom 552s Multiple R-squared: 0.1193, Adjusted R-squared: 0.08097 552s F-statistic: 3.115 on 2 and 46 DF, p-value: 0.05388 552s 552s e0 b1 b2 552s e0 8.454726e-03 -7.868733e-05 1.608713e-07 552s b1 -7.868733e-05 2.149290e-06 -6.145868e-09 552s b2 1.608713e-07 -6.145868e-09 1.936461e-11 552s (Intercept) x I(x^2) 552s (Intercept) 8.454726e-03 -7.868733e-05 1.608713e-07 552s x -7.868733e-05 2.149290e-06 -6.145868e-09 552s I(x^2) 1.608713e-07 -6.145868e-09 1.936461e-11 552s $fit 552s [1] 0.49280484 0.00000000 0.05861756 0.00000000 0.25773527 0.00000000 552s [7] 0.05861756 0.00000000 0.25773527 0.05861756 0.25773527 -0.01991690 552s [13] 0.05861756 -0.01991690 0.05861756 0.02376374 0.05861756 0.05861756 552s [19] 0.02376374 0.49280484 0.00000000 0.49280484 0.00000000 0.05861756 552s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.02376374 552s [31] 0.25773527 0.00000000 0.25773527 -0.01991690 0.25773527 0.00000000 552s [37] 0.00000000 0.00000000 0.25773527 0.00000000 0.25773527 -0.01991690 552s [43] 0.25773527 0.02376374 0.05861756 -0.01991690 0.00000000 0.25773527 552s [49] 0.00000000 552s 552s $se.fit 552s [1] 0.19776187 0.00000000 0.13594191 0.00000000 0.13486241 0.00000000 552s [7] 0.13594191 0.00000000 0.13486241 0.13594191 0.13486241 0.09012454 552s [13] 0.13594191 0.09012454 0.13594191 0.13105561 0.13594191 0.13594191 552s [19] 0.13105561 0.19776187 0.00000000 0.19776187 0.00000000 0.13594191 552s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.13105561 552s [31] 0.13486241 0.00000000 0.13486241 0.09012454 0.13486241 0.00000000 552s [37] 0.00000000 0.00000000 0.13486241 0.00000000 0.13486241 0.09012454 552s [43] 0.13486241 0.13105561 0.13594191 0.09012454 0.00000000 0.13486241 552s [49] 0.00000000 552s 552s $fit 552s [1] -3.118383 -3.124477 -3.132746 552s 552s $se.fit 552s [1] 0.09194958 0.08435629 0.08409705 552s 552s $fit 552s 1 2 3 552s -3.118383 -3.124477 -3.132746 552s 552s $se.fit 552s 1 2 3 552s 0.09194958 0.08435629 0.08409705 552s 552s $df 552s [1] 46 552s 552s $residual.scale 552s [1] 0.4007027 552s 552s [1] 508.0679 552s [1] 62.95473 552s [1] 62.95473 552s Dose Response Model 552s 552s Model: quadratic 552s Fit-type: normal 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -0.87232 -0.24673 -0.00516 0.29930 0.65583 552s 552s Coefficients with approx. stand. error: 552s Estimate Std. Error 552s e0 -3.08e+00 1.69e-01 552s b1 -5.76e-04 1.59e-03 552s b2 4.82e-06 4.74e-06 552s age -1.60e-03 2.09e-03 552s centergreen -4.89e-03 2.03e-01 552s centerred 6.72e-02 1.75e-01 552s centersilver 7.81e-02 1.87e-01 552s centeryellow 9.70e-02 1.95e-01 552s 552s Residual standard error: 0.418 552s Degrees of freedom: 41 552s 552s Call: 552s lm(formula = y ~ x + I(x^2) + age + center, data = datset) 552s 552s Residuals: 552s Min 1Q Median 3Q Max 552s -0.65583 -0.29930 0.00516 0.24673 0.87232 552s 552s Coefficients: 552s Estimate Std. Error t value Pr(>|t|) 552s (Intercept) -3.076e+00 1.692e-01 -18.182 <2e-16 *** 552s x -5.756e-04 1.594e-03 -0.361 0.720 552s I(x^2) 4.822e-06 4.738e-06 1.018 0.315 552s age -1.604e-03 2.092e-03 -0.767 0.448 552s centergreen -4.891e-03 2.034e-01 -0.024 0.981 552s centerred 6.715e-02 1.753e-01 0.383 0.704 552s centersilver 7.814e-02 1.875e-01 0.417 0.679 552s centeryellow 9.700e-02 1.950e-01 0.497 0.622 552s --- 552s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 552s 552s Residual standard error: 0.4185 on 41 degrees of freedom 552s Multiple R-squared: 0.1437, Adjusted R-squared: -0.002451 552s F-statistic: 0.9832 on 7 and 41 DF, p-value: 0.4566 552s 552s e0 b1 b2 age 552s e0 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 552s b1 -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 552s b2 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 552s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 552s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 552s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 552s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 552s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 552s centergreen centerred centersilver centeryellow 552s e0 -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 552s b1 -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 552s b2 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 552s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 552s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 552s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 552s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 552s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 552s (Intercept) x I(x^2) age 552s (Intercept) 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 552s x -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 552s I(x^2) 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 552s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 552s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 552s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 552s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 552s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 552s centergreen centerred centersilver centeryellow 552s (Intercept) -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 552s x -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 552s I(x^2) 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 552s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 552s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 552s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 552s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 552s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 552s $fit 552s [1] -3.124527 -3.129801 -3.133870 552s 552s $se.fit 552s [1] 0.1418548 0.1377349 0.1475950 552s 552s $fit 552s 1 2 3 552s -3.124527 -3.129801 -3.133870 552s 552s $se.fit 552s 1 2 3 552s 0.1418548 0.1377349 0.1475950 552s 552s $df 552s [1] 41 552s 552s $residual.scale 552s [1] 0.418494 552s 552s [1] 215.5724 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552s [1] 0 0 0 0 0 552s [1] 0 0 0 0 0 552s Warning message: 552s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 552s mns is not a numeric but a array, converting with as.numeric() 552s Warning message: 552s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 552s mns is not a numeric but a array, converting with as.numeric() 552s e0 delta 552s 0.47569910 0.02447331 552s e0 delta 552s 0.47569910 0.02447331 552s Warning message: 552s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 552s mns is not a numeric but a array, converting with as.numeric() 552s Warning message: 552s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 552s mns is not a numeric but a array, converting with as.numeric() 552s testsFitting.R passed 553s Loading required package: DoseFinding 555s testsMCPMod.R passed 555s Loading required package: DoseFinding 556s Loading required package: multcomp 556s Loading required package: mvtnorm 556s Loading required package: survival 557s Loading required package: TH.data 557s Loading required package: MASS 557s 557s Attaching package: ‘TH.data’ 557s 557s The following object is masked from ‘package:MASS’: 557s 557s geyser 557s 557s 557s Simultaneous Tests for General Linear Hypotheses 557s 557s Multiple Comparisons of Means: User-defined Contrasts 557s 557s 557s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 557s 557s Linear Hypotheses: 557s Estimate Std. Error t value Pr(>t) 557s linear <= 0 0.07260 0.05755 1.262 0.1756 557s betaMod <= 0 0.12179 0.05559 2.191 0.0287 * 557s sigEmax <= 0 0.08677 0.05648 1.536 0.1114 557s --- 557s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 557s (Adjusted p values reported -- single-step method) 557s 557s Multiple Contrast Test 557s 557s Contrasts: 557s linear betaMod sigEmax 557s 0 -0.472 -0.492 -0.349 557s 172 -0.391 -0.345 -0.489 557s 285 -0.132 0.032 -0.240 557s 516 0.262 0.799 0.503 557s 761 0.733 0.007 0.574 557s 557s Contrast Correlation: 557s linear betaMod sigEmax 557s linear 1.000 0.645 0.942 557s betaMod 0.645 1.000 0.741 557s sigEmax 0.942 0.741 1.000 557s 557s Multiple Contrast Test: 557s t-Stat adj-p 557s betaMod 2.191 0.0287 557s sigEmax 1.536 0.1112 557s linear 1.262 0.1757 557s 557s Simultaneous Tests for General Linear Hypotheses 557s 557s Multiple Comparisons of Means: User-defined Contrasts 557s 557s 557s Fit: lm(formula = y ~ x, data = dd2) 557s 557s Linear Hypotheses: 557s Estimate Std. Error t value Pr(>t) 557s linear <= 0 0.07985 0.05691 1.403 0.1404 557s betaMod <= 0 0.11839 0.05507 2.150 0.0314 * 557s sigEmax <= 0 0.09407 0.05594 1.682 0.0853 . 557s --- 557s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 557s (Adjusted p values reported -- single-step method) 557s 557s Multiple Contrast Test 557s 557s Contrasts: 557s linear betaMod sigEmax 557s 0 -0.472 -0.487 -0.347 557s 172 -0.389 -0.348 -0.490 557s 285 -0.132 0.030 -0.239 557s 516 0.255 0.800 0.500 557s 761 0.738 0.005 0.576 557s 557s Contrast Correlation: 557s linear betaMod sigEmax 557s linear 1.000 0.642 0.941 557s betaMod 0.642 1.000 0.740 557s sigEmax 0.941 0.740 1.000 557s 557s Multiple Contrast Test: 557s t-Stat adj-p 557s betaMod 2.150 0.0317 557s sigEmax 1.682 0.0852 557s linear 1.403 0.1403 557s 557s Simultaneous Tests for General Linear Hypotheses 557s 557s Multiple Comparisons of Means: User-defined Contrasts 557s 557s 557s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 557s 557s Linear Hypotheses: 557s Estimate Std. Error t value Pr(>t) 557s linlog <= 0 0.09114 0.05971 1.526 0.1510 557s logistic1 <= 0 0.10293 0.05761 1.787 0.0940 . 557s logistic2 <= 0 0.09583 0.05707 1.679 0.1154 557s exponential <= 0 0.02544 0.05514 0.461 0.5623 557s quadratic <= 0 0.11676 0.05980 1.952 0.0674 . 557s --- 557s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 557s (Adjusted p values reported -- single-step method) 557s 557s Multiple Contrast Test 557s 557s Contrasts: 557s linlog logistic1 logistic2 exponential quadratic 557s 0 -0.624 -0.448 -0.457 -0.268 -0.665 557s 172 -0.309 -0.590 -0.475 -0.347 -0.055 557s 285 -0.049 0.101 -0.118 -0.191 0.199 557s 516 0.366 0.500 0.499 -0.069 0.696 557s 761 0.616 0.437 0.550 0.875 -0.174 557s 557s Contrast Correlation: 557s linlog logistic1 logistic2 exponential quadratic 557s linlog 1.000 0.902 0.955 0.799 0.651 557s logistic1 0.902 1.000 0.949 0.671 0.660 557s logistic2 0.955 0.949 1.000 0.792 0.586 557s exponential 0.799 0.671 0.792 1.000 0.063 557s quadratic 0.651 0.660 0.586 0.063 1.000 557s 557s Multiple Contrast Test: 557s t-Stat adj-p 557s quadratic 1.952 0.0675 557s logistic1 1.787 0.0941 557s logistic2 1.679 0.1154 557s linlog 1.526 0.1506 557s exponential 0.461 0.5625 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: lm(formula = y ~ x, data = dd2) 558s 558s Linear Hypotheses: 558s Estimate Std. Error t value Pr(>t) 558s linlog <= 0 0.09484 0.05913 1.604 0.1320 558s logistic1 <= 0 0.10608 0.05706 1.859 0.0817 . 558s logistic2 <= 0 0.10119 0.05654 1.790 0.0928 . 558s exponential <= 0 0.03666 0.05440 0.674 0.4665 558s quadratic <= 0 0.10792 0.05938 1.817 0.0885 . 558s --- 558s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linlog logistic1 logistic2 exponential quadratic 558s 0 -0.623 -0.445 -0.455 -0.270 -0.664 558s 172 -0.307 -0.592 -0.476 -0.342 -0.056 558s 285 -0.050 0.101 -0.118 -0.189 0.197 558s 516 0.358 0.497 0.496 -0.076 0.698 558s 761 0.622 0.440 0.554 0.877 -0.175 558s 558s Contrast Correlation: 558s linlog logistic1 logistic2 exponential quadratic 558s linlog 1.000 0.901 0.955 0.800 0.648 558s logistic1 0.901 1.000 0.949 0.670 0.658 558s logistic2 0.955 0.949 1.000 0.792 0.584 558s exponential 0.800 0.670 0.792 1.000 0.062 558s quadratic 0.648 0.658 0.584 0.062 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s logistic1 1.859 0.0816 558s quadratic 1.817 0.0887 558s logistic2 1.790 0.0933 558s linlog 1.604 0.1316 558s exponential 0.674 0.4667 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: lm(formula = y ~ x, data = dd2) 558s 558s Linear Hypotheses: 558s Estimate Std. Error t value Pr(>t) 558s linlog <= 0 -0.2995 1.0212 -0.293 0.821 558s logistic1 <= 0 -0.1795 0.9837 -0.182 0.785 558s logistic2 <= 0 -0.1401 0.9877 -0.142 0.771 558s exponential <= 0 -0.2892 0.9568 -0.302 0.823 558s quadratic <= 0 -0.1973 1.2830 -0.154 0.776 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linlog logistic1 logistic2 exponential quadratic 558s 0 -0.464 -0.268 -0.289 -0.207 -0.751 558s 124 -0.436 -0.627 -0.556 -0.450 -0.241 558s 272 0.013 -0.006 -0.083 -0.187 0.476 558s 560 0.127 0.196 0.172 -0.004 0.353 558s 865 0.761 0.705 0.755 0.848 0.164 558s 558s Contrast Correlation: 558s linlog logistic1 logistic2 exponential quadratic 558s linlog 1.000 0.950 0.963 0.890 0.665 558s logistic1 0.950 1.000 0.992 0.879 0.591 558s logistic2 0.963 0.992 1.000 0.922 0.542 558s exponential 0.890 0.879 0.922 1.000 0.252 558s quadratic 0.665 0.591 0.542 0.252 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s logistic2 -0.142 0.771 558s quadratic -0.154 0.776 558s logistic1 -0.182 0.785 558s linlog -0.293 0.821 558s exponential -0.302 0.823 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 558s 558s Linear Hypotheses: 558s Estimate Std. Error z value Pr(>z) 558s linear <= 0 0.19645 0.33561 0.585 0.395 558s betaMod <= 0 0.03813 0.31565 0.121 0.587 558s sigEmax <= 0 0.30472 0.34592 0.881 0.283 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linear betaMod sigEmax 558s 0 -0.794 -0.793 -0.774 558s 190 -0.064 -0.022 -0.192 558s 344 0.197 0.577 0.317 558s 404 0.098 0.190 0.163 558s 616 0.563 0.048 0.487 558s 558s Contrast Correlation: 558s linear betaMod sigEmax 558s linear 1.000 0.723 0.962 558s betaMod 0.723 1.000 0.793 558s sigEmax 0.962 0.793 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s sigEmax 0.881 0.283 558s linear 0.585 0.395 558s betaMod 0.121 0.587 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 558s 558s Linear Hypotheses: 558s Estimate Std. Error z value Pr(>z) 558s linear <= 0 0.2547 0.1877 1.357 0.1500 558s betaMod <= 0 0.2367 0.2371 0.999 0.2555 558s sigEmax <= 0 0.3698 0.1889 1.958 0.0476 * 558s --- 558s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linear betaMod sigEmax 558s 0 0.418 0.634 0.310 558s 68.5 0.114 0.150 0.139 558s 85.9 0.387 0.362 0.551 558s 166 0.027 -0.572 -0.033 558s 197 -0.015 -0.158 -0.054 558s 278 -0.129 -0.264 -0.172 558s 332 -0.803 -0.152 -0.740 558s 558s Contrast Correlation: 558s linear betaMod sigEmax 558s linear 1.000 0.635 0.967 558s betaMod 0.635 1.000 0.677 558s sigEmax 0.967 0.677 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s sigEmax 1.958 0.0477 558s linear 1.357 0.1501 558s betaMod 0.999 0.2556 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 558s 558s Linear Hypotheses: 558s Estimate Std. Error z value Pr(>z) 558s linear <= 0 0.3391 0.3218 1.054 0.226 558s betaMod <= 0 0.3556 0.3124 1.138 0.201 558s sigEmax <= 0 0.2935 0.3497 0.839 0.299 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linear betaMod sigEmax 558s 0 -0.721 -0.796 -0.547 558s 79.1 -0.129 -0.102 -0.312 558s 117 0.005 0.106 -0.137 558s 208 0.191 0.519 0.288 558s 398 0.654 0.274 0.708 558s 558s Contrast Correlation: 558s linear betaMod sigEmax 558s linear 1.000 0.785 0.954 558s betaMod 0.785 1.000 0.742 558s sigEmax 0.954 0.742 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s betaMod 1.138 0.201 558s linear 1.054 0.226 558s sigEmax 0.839 0.299 558s Warning message: 558s In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 558s Warning from mvtnorm::pmvt: univariate: using pnorm. 558s 558s Simultaneous Tests for General Linear Hypotheses 558s 558s Multiple Comparisons of Means: User-defined Contrasts 558s 558s 558s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 558s 558s Linear Hypotheses: 558s Estimate Std. Error z value Pr(>z) 558s linear <= 0 0.3391 0.3218 1.054 0.146 558s (Adjusted p values reported -- single-step method) 558s 558s Multiple Contrast Test 558s 558s Contrasts: 558s linear 558s 0 -0.721 558s 79.1 -0.129 558s 117 0.005 558s 208 0.191 558s 398 0.654 558s 558s Contrast Correlation: 558s linear 558s linear 1 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s linear 1.054 0.146 558s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 558s Dose Response Model 558s 558s Model: sigEmax 558s Fit-type: general 558s 558s Coefficients dose-response model 558s eMax ed50 h 558s 0.4714 0.4880 0.5000 558s 558s Fitted to: 558s 1 2 3 4 558s 0.2846 0.2965 0.3502 0.3480 558s 558s Generalized residual sum of squares: 0.07825 558s Multiple Contrast Test 558s 558s Contrasts: 558s emax linear logistic linInt 558s 1 0.462 -0.429 0.511 -0.672 558s 2 0.505 0.002 0.507 0.437 558s 3 0.504 0.400 0.485 0.418 558s 4 0.527 0.810 0.497 0.428 558s 558s Contrast Correlation: 558s emax linear logistic linInt 558s emax 1.000 0.715 1.000 0.617 558s linear 0.715 1.000 0.698 0.863 558s logistic 1.000 0.698 1.000 0.598 558s linInt 0.617 0.863 0.598 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s emax 3.178 0.00193 558s logistic 3.164 0.00194 558s linear 2.640 0.00968 558s linInt 2.247 0.02721 558s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 558s Dose Response Model 558s 558s Model: sigEmax 558s Fit-type: general 558s 558s Coefficients dose-response model 558s eMax ed50 h 558s 0.4714 0.4880 0.5000 558s 558s Fitted to: 558s 3 4 1 2 558s 0.3502 0.3480 0.2846 0.2965 558s 558s Generalized residual sum of squares: 0.07825 558s Multiple Contrast Test 558s 558s Contrasts: 558s emax linear logistic linInt 558s 1 0.462 -0.429 0.511 -0.672 558s 2 0.505 0.002 0.507 0.437 558s 3 0.504 0.400 0.485 0.418 558s 4 0.527 0.810 0.497 0.428 558s 558s Contrast Correlation: 558s emax linear logistic linInt 558s emax 1.000 0.715 1.000 0.617 558s linear 0.715 1.000 0.698 0.863 558s logistic 1.000 0.698 1.000 0.598 558s linInt 0.617 0.863 0.598 1.000 558s 558s Multiple Contrast Test: 558s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 558s t-Stat adj-p 558s emax 3.178 0.00213 558s logistic 3.164 0.00174 558s linear 2.640 0.00941 558s linInt 2.247 0.02663 558s Dose Response Model 558s 558s Model: sigEmax 558s Fit-type: general 558s 558s Coefficients dose-response model 558s e0 eMax ed50 h 558s 0.2171 0.4714 0.4860 0.5000 558s 558s Fitted to: 558s 0 1 2 3 4 558s 0.2169 0.5016 0.5138 0.5677 0.5648 558s 558s Generalized residual sum of squares: 0.07892 558s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 558s Multiple Contrast Test 558s 558s Contrasts: 558s emax linear logistic linInt 558s 0 -0.894 -0.617 -0.894 -0.522 558s 1 0.207 -0.338 0.228 -0.573 558s 2 0.226 0.002 0.227 0.373 558s 3 0.227 0.315 0.218 0.358 558s 4 0.235 0.637 0.221 0.363 558s 558s Contrast Correlation: 558s emax linear logistic linInt 558s emax 1.000 0.715 1.000 0.618 558s linear 0.715 1.000 0.698 0.863 558s logistic 1.000 0.698 1.000 0.599 558s linInt 0.618 0.863 0.599 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s emax 3.186 0.00184 558s logistic 3.172 0.00177 558s linear 2.645 0.00956 558s linInt 2.254 0.02649 558s Dose Response Model 558s 558s Model: sigEmax 558s Fit-type: general 558s 558s Coefficients dose-response model 558s e0 eMax ed50 h 558s 0.2171 0.4714 0.4860 0.5000 558s 558s Fitted to: 558s 2 3 0 1 4 558s 0.5138 0.5677 0.2169 0.5016 0.5648 558s 558s Generalized residual sum of squares: 0.07892 558s Multiple Contrast Test 558s 558s Contrasts: 558s emax linear logistic linInt 558s 0 -0.894 -0.617 -0.894 -0.522 558s 1 0.207 -0.338 0.228 -0.573 558s 2 0.226 0.002 0.227 0.373 558s 3 0.227 0.315 0.218 0.358 558s 4 0.235 0.637 0.221 0.363 558s 558s Contrast Correlation: 558s emax linear logistic linInt 558s emax 1.000 0.715 1.000 0.618 558s linear 0.715 1.000 0.698 0.863 558s logistic 1.000 0.698 1.000 0.599 558s linInt 0.618 0.863 0.599 1.000 558s 558s Multiple Contrast Test: 558s t-Stat adj-p 558s emax 3.186 0.00163 558s logistic 3.172 0.00192 558s linear 2.645 0.00981 558s linInt 2.254 0.02699 558s Warning messages: 558s 1: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 558s Warning from mvtnorm::pmvt: Covariance matrix not positive semidefinite. 558s 2: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 558s Setting calculated p-value to NA 558s [1] TRUE 558s testsMCT.R passed 558s Loading required package: DoseFinding 559s Loading required package: quadprog 559s Loading required package: Rsolnp 559s testsoptContr.R passed 559s testsplotDRMod.R consists only from comments and returns non-zero exit value ... ignored 559s testssampSize.R passed 559s Loading required package: DoseFinding 561s [1] 0.3076509 561s [1] 0.6153019 561s [1] 0.9229528 561s [1] 2.673503 561s [1] 0.7028559 561s [1] 2.064397 561s [1] NA 561s testssamplMod.R passed 563s /usr/bin/xdg-open: 1032: www-browser: not found 563s /usr/bin/xdg-open: 1032: links2: not found 563s /usr/bin/xdg-open: 1032: elinks: not found 563s /usr/bin/xdg-open: 1032: links: not found 563s /usr/bin/xdg-open: 1032: lynx: not found 563s /usr/bin/xdg-open: 1032: w3m: not found 563s xdg-open: no method available for opening 'https://huisophiesunrshiny.shinyapps.io/designmcpmod/' 563s [ FAIL 0 | WARN 0 | SKIP 0 | PASS 53 ] 563s testthat.R passed 564s autopkgtest [23:26:04]: test run-unit-test: -----------------------] 568s autopkgtest [23:26:08]: test run-unit-test: - - - - - - - - - - results - - - - - - - - - - 568s run-unit-test PASS 571s autopkgtest [23:26:11]: test pkg-r-autopkgtest: preparing testbed 573s Reading package lists... 574s Building dependency tree... 574s Reading state information... 574s Solving dependencies... 574s The following NEW packages will be installed: 574s build-essential cpp cpp-15 cpp-15-arm-linux-gnueabihf 574s cpp-arm-linux-gnueabihf dctrl-tools g++ g++-15 g++-15-arm-linux-gnueabihf 574s g++-arm-linux-gnueabihf gcc gcc-15 gcc-15-arm-linux-gnueabihf 574s gcc-arm-linux-gnueabihf gfortran gfortran-15 gfortran-15-arm-linux-gnueabihf 574s gfortran-arm-linux-gnueabihf icu-devtools libasan8 libblas-dev libbz2-dev 574s libc-dev-bin libc6-dev libcc1-0 libcrypt-dev libdeflate-dev libgcc-15-dev 574s libgfortran-15-dev libicu-dev libisl23 libjpeg-dev libjpeg-turbo8-dev 574s libjpeg8-dev liblapack-dev liblzma-dev libmpc3 libncurses-dev libpcre2-16-0 574s libpcre2-32-0 libpcre2-dev libpcre2-posix3 libpkgconf3 libpng-dev 574s libreadline-dev libstdc++-15-dev libtirpc-dev libubsan1 libzstd-dev 574s linux-libc-dev pkg-r-autopkgtest pkgconf pkgconf-bin r-base-dev rpcsvc-proto 574s zlib1g-dev 575s 0 upgraded, 56 newly installed, 0 to remove and 0 not upgraded. 575s Need to get 83.1 MB of archives. 575s After this operation, 253 MB of additional disk space will be used. 575s Get:1 http://ftpmaster.internal/ubuntu resolute/main armhf libc-dev-bin armhf 2.42-2ubuntu4 [21.8 kB] 575s Get:2 http://ftpmaster.internal/ubuntu resolute/main armhf linux-libc-dev armhf 6.19.0-3.3 [1804 kB] 578s Get:3 http://ftpmaster.internal/ubuntu resolute/main armhf libcrypt-dev armhf 1:4.5.1-1 [128 kB] 578s Get:4 http://ftpmaster.internal/ubuntu resolute/main armhf rpcsvc-proto armhf 1.4.3-1build1 [62.6 kB] 578s Get:5 http://ftpmaster.internal/ubuntu resolute/main armhf libc6-dev armhf 2.42-2ubuntu4 [1416 kB] 581s Get:6 http://ftpmaster.internal/ubuntu resolute/main armhf libisl23 armhf 0.27-1build1 [553 kB] 582s Get:7 http://ftpmaster.internal/ubuntu resolute/main armhf libmpc3 armhf 1.3.1-2 [47.0 kB] 582s Get:8 http://ftpmaster.internal/ubuntu resolute/main armhf cpp-15-arm-linux-gnueabihf armhf 15.2.0-12ubuntu1 [10.1 MB] 599s Get:9 http://ftpmaster.internal/ubuntu resolute/main armhf cpp-15 armhf 15.2.0-12ubuntu1 [1032 B] 599s Get:10 http://ftpmaster.internal/ubuntu resolute/main armhf cpp-arm-linux-gnueabihf armhf 4:15.2.0-4ubuntu1 [5756 B] 599s Get:11 http://ftpmaster.internal/ubuntu resolute/main armhf cpp armhf 4:15.2.0-4ubuntu1 [22.4 kB] 599s Get:12 http://ftpmaster.internal/ubuntu resolute/main armhf libcc1-0 armhf 15.2.0-12ubuntu1 [43.5 kB] 599s Get:13 http://ftpmaster.internal/ubuntu resolute/main armhf libasan8 armhf 15.2.0-12ubuntu1 [2949 kB] 605s Get:14 http://ftpmaster.internal/ubuntu resolute/main armhf libubsan1 armhf 15.2.0-12ubuntu1 [1187 kB] 606s Get:15 http://ftpmaster.internal/ubuntu resolute/main armhf libgcc-15-dev armhf 15.2.0-12ubuntu1 [898 kB] 608s Get:16 http://ftpmaster.internal/ubuntu resolute/main armhf gcc-15-arm-linux-gnueabihf armhf 15.2.0-12ubuntu1 [19.5 MB] 645s Get:17 http://ftpmaster.internal/ubuntu resolute/main armhf gcc-15 armhf 15.2.0-12ubuntu1 [499 kB] 646s Get:18 http://ftpmaster.internal/ubuntu resolute/main armhf gcc-arm-linux-gnueabihf armhf 4:15.2.0-4ubuntu1 [1220 B] 646s Get:19 http://ftpmaster.internal/ubuntu resolute/main armhf gcc armhf 4:15.2.0-4ubuntu1 [5022 B] 646s Get:20 http://ftpmaster.internal/ubuntu resolute/main armhf libstdc++-15-dev armhf 15.2.0-12ubuntu1 [2638 kB] 650s Get:21 http://ftpmaster.internal/ubuntu resolute/main armhf g++-15-arm-linux-gnueabihf armhf 15.2.0-12ubuntu1 [11.4 MB] 671s Get:22 http://ftpmaster.internal/ubuntu resolute/main armhf g++-15 armhf 15.2.0-12ubuntu1 [25.3 kB] 671s Get:23 http://ftpmaster.internal/ubuntu resolute/main armhf g++-arm-linux-gnueabihf armhf 4:15.2.0-4ubuntu1 [968 B] 671s Get:24 http://ftpmaster.internal/ubuntu resolute/main armhf g++ armhf 4:15.2.0-4ubuntu1 [1086 B] 671s Get:25 http://ftpmaster.internal/ubuntu resolute/main armhf build-essential armhf 12.12ubuntu2 [5256 B] 671s Get:26 http://ftpmaster.internal/ubuntu resolute/main armhf dctrl-tools armhf 2.24-3build4 [95.0 kB] 671s Get:27 http://ftpmaster.internal/ubuntu resolute/main armhf libgfortran-15-dev armhf 15.2.0-12ubuntu1 [380 kB] 672s Get:28 http://ftpmaster.internal/ubuntu resolute/main armhf gfortran-15-arm-linux-gnueabihf armhf 15.2.0-12ubuntu1 [10.7 MB] 691s Get:29 http://ftpmaster.internal/ubuntu resolute/main armhf gfortran-15 armhf 15.2.0-12ubuntu1 [18.1 kB] 691s Get:30 http://ftpmaster.internal/ubuntu resolute/main armhf gfortran-arm-linux-gnueabihf armhf 4:15.2.0-4ubuntu1 [1020 B] 691s Get:31 http://ftpmaster.internal/ubuntu resolute/main armhf gfortran armhf 4:15.2.0-4ubuntu1 [1162 B] 691s Get:32 http://ftpmaster.internal/ubuntu resolute/main armhf icu-devtools armhf 78.2-1ubuntu1 [203 kB] 691s Get:33 http://ftpmaster.internal/ubuntu resolute/main armhf libblas-dev armhf 3.12.1-7ubuntu1 [141 kB] 692s Get:34 http://ftpmaster.internal/ubuntu resolute/main armhf libbz2-dev armhf 1.0.8-6build2 [31.2 kB] 692s Get:35 http://ftpmaster.internal/ubuntu resolute/main armhf libdeflate-dev armhf 1.23-2build1 [45.1 kB] 692s Get:36 http://ftpmaster.internal/ubuntu resolute/main armhf libicu-dev armhf 78.2-1ubuntu1 [12.2 MB] 714s Get:37 http://ftpmaster.internal/ubuntu resolute/main armhf libjpeg-turbo8-dev armhf 2.1.5-4ubuntu3 [265 kB] 714s Get:38 http://ftpmaster.internal/ubuntu resolute/main armhf libjpeg8-dev armhf 8c-2ubuntu11 [1484 B] 714s Get:39 http://ftpmaster.internal/ubuntu resolute/main armhf libjpeg-dev armhf 8c-2ubuntu11 [1482 B] 714s Get:40 http://ftpmaster.internal/ubuntu resolute/main armhf liblapack-dev armhf 3.12.1-7ubuntu1 [2207 kB] 719s Get:41 http://ftpmaster.internal/ubuntu resolute/main armhf libncurses-dev armhf 6.6+20251231-1 [348 kB] 720s Get:42 http://ftpmaster.internal/ubuntu resolute/main armhf libpcre2-16-0 armhf 10.46-1 [206 kB] 721s Get:43 http://ftpmaster.internal/ubuntu resolute/main armhf libpcre2-32-0 armhf 10.46-1 [197 kB] 721s Get:44 http://ftpmaster.internal/ubuntu resolute/main armhf libpcre2-posix3 armhf 10.46-1 [6286 B] 721s Get:45 http://ftpmaster.internal/ubuntu resolute/main armhf libpcre2-dev armhf 10.46-1 [744 kB] 723s Get:46 http://ftpmaster.internal/ubuntu resolute/main armhf libpkgconf3 armhf 1.8.1-4build1 [26.6 kB] 723s Get:47 http://ftpmaster.internal/ubuntu resolute/main armhf zlib1g-dev armhf 1:1.3.dfsg+really1.3.1-1ubuntu2 [881 kB] 726s Get:48 http://ftpmaster.internal/ubuntu resolute/main armhf libpng-dev armhf 1.6.54-1 [252 kB] 727s Get:49 http://ftpmaster.internal/ubuntu resolute/main armhf libreadline-dev armhf 8.3-3 [165 kB] 727s Get:50 http://ftpmaster.internal/ubuntu resolute/main armhf libzstd-dev armhf 1.5.7+dfsg-3 [342 kB] 728s Get:51 http://ftpmaster.internal/ubuntu resolute/main armhf liblzma-dev armhf 5.8.2-2 [167 kB] 728s Get:52 http://ftpmaster.internal/ubuntu resolute/main armhf pkgconf-bin armhf 1.8.1-4build1 [21.4 kB] 728s Get:53 http://ftpmaster.internal/ubuntu resolute/main armhf pkgconf armhf 1.8.1-4build1 [16.8 kB] 728s Get:54 http://ftpmaster.internal/ubuntu resolute/main armhf libtirpc-dev armhf 1.3.6+ds-1 [184 kB] 729s Get:55 http://ftpmaster.internal/ubuntu resolute/universe armhf r-base-dev all 4.5.2-1ubuntu2 [1880 B] 729s Get:56 http://ftpmaster.internal/ubuntu resolute/universe armhf pkg-r-autopkgtest all 20250812 [6158 B] 729s Fetched 83.1 MB in 2min 34s (538 kB/s) 729s Selecting previously unselected package libc-dev-bin. 729s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 85763 files and directories currently installed.) 730s Preparing to unpack .../00-libc-dev-bin_2.42-2ubuntu4_armhf.deb ... 730s Unpacking libc-dev-bin (2.42-2ubuntu4) ... 730s Selecting previously unselected package linux-libc-dev:armhf. 730s Preparing to unpack .../01-linux-libc-dev_6.19.0-3.3_armhf.deb ... 730s Unpacking linux-libc-dev:armhf (6.19.0-3.3) ... 730s Selecting previously unselected package libcrypt-dev:armhf. 730s Preparing to unpack .../02-libcrypt-dev_1%3a4.5.1-1_armhf.deb ... 730s Unpacking libcrypt-dev:armhf (1:4.5.1-1) ... 730s Selecting previously unselected package rpcsvc-proto. 730s Preparing to unpack .../03-rpcsvc-proto_1.4.3-1build1_armhf.deb ... 730s Unpacking rpcsvc-proto (1.4.3-1build1) ... 730s Selecting previously unselected package libc6-dev:armhf. 730s Preparing to unpack .../04-libc6-dev_2.42-2ubuntu4_armhf.deb ... 730s Unpacking libc6-dev:armhf (2.42-2ubuntu4) ... 730s Selecting previously unselected package libisl23:armhf. 730s Preparing to unpack .../05-libisl23_0.27-1build1_armhf.deb ... 730s Unpacking libisl23:armhf (0.27-1build1) ... 730s Selecting previously unselected package libmpc3:armhf. 730s Preparing to unpack .../06-libmpc3_1.3.1-2_armhf.deb ... 730s Unpacking libmpc3:armhf (1.3.1-2) ... 730s Selecting previously unselected package cpp-15-arm-linux-gnueabihf. 730s Preparing to unpack .../07-cpp-15-arm-linux-gnueabihf_15.2.0-12ubuntu1_armhf.deb ... 730s Unpacking cpp-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 730s Selecting previously unselected package cpp-15. 730s Preparing to unpack .../08-cpp-15_15.2.0-12ubuntu1_armhf.deb ... 730s Unpacking cpp-15 (15.2.0-12ubuntu1) ... 730s Selecting previously unselected package cpp-arm-linux-gnueabihf. 730s Preparing to unpack .../09-cpp-arm-linux-gnueabihf_4%3a15.2.0-4ubuntu1_armhf.deb ... 730s Unpacking cpp-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 730s Selecting previously unselected package cpp. 730s Preparing to unpack .../10-cpp_4%3a15.2.0-4ubuntu1_armhf.deb ... 730s Unpacking cpp (4:15.2.0-4ubuntu1) ... 730s Selecting previously unselected package libcc1-0:armhf. 730s Preparing to unpack .../11-libcc1-0_15.2.0-12ubuntu1_armhf.deb ... 730s Unpacking libcc1-0:armhf (15.2.0-12ubuntu1) ... 730s Selecting previously unselected package libasan8:armhf. 730s Preparing to unpack .../12-libasan8_15.2.0-12ubuntu1_armhf.deb ... 730s Unpacking libasan8:armhf (15.2.0-12ubuntu1) ... 731s Selecting previously unselected package libubsan1:armhf. 731s Preparing to unpack .../13-libubsan1_15.2.0-12ubuntu1_armhf.deb ... 731s Unpacking libubsan1:armhf (15.2.0-12ubuntu1) ... 731s Selecting previously unselected package libgcc-15-dev:armhf. 731s Preparing to unpack .../14-libgcc-15-dev_15.2.0-12ubuntu1_armhf.deb ... 731s Unpacking libgcc-15-dev:armhf (15.2.0-12ubuntu1) ... 731s Selecting previously unselected package gcc-15-arm-linux-gnueabihf. 731s Preparing to unpack .../15-gcc-15-arm-linux-gnueabihf_15.2.0-12ubuntu1_armhf.deb ... 731s Unpacking gcc-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 731s Selecting previously unselected package gcc-15. 731s Preparing to unpack .../16-gcc-15_15.2.0-12ubuntu1_armhf.deb ... 731s Unpacking gcc-15 (15.2.0-12ubuntu1) ... 731s Selecting previously unselected package gcc-arm-linux-gnueabihf. 731s Preparing to unpack .../17-gcc-arm-linux-gnueabihf_4%3a15.2.0-4ubuntu1_armhf.deb ... 731s Unpacking gcc-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 731s Selecting previously unselected package gcc. 731s Preparing to unpack .../18-gcc_4%3a15.2.0-4ubuntu1_armhf.deb ... 731s Unpacking gcc (4:15.2.0-4ubuntu1) ... 731s Selecting previously unselected package libstdc++-15-dev:armhf. 731s Preparing to unpack .../19-libstdc++-15-dev_15.2.0-12ubuntu1_armhf.deb ... 731s Unpacking libstdc++-15-dev:armhf (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package g++-15-arm-linux-gnueabihf. 732s Preparing to unpack .../20-g++-15-arm-linux-gnueabihf_15.2.0-12ubuntu1_armhf.deb ... 732s Unpacking g++-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package g++-15. 732s Preparing to unpack .../21-g++-15_15.2.0-12ubuntu1_armhf.deb ... 732s Unpacking g++-15 (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package g++-arm-linux-gnueabihf. 732s Preparing to unpack .../22-g++-arm-linux-gnueabihf_4%3a15.2.0-4ubuntu1_armhf.deb ... 732s Unpacking g++-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 732s Selecting previously unselected package g++. 732s Preparing to unpack .../23-g++_4%3a15.2.0-4ubuntu1_armhf.deb ... 732s Unpacking g++ (4:15.2.0-4ubuntu1) ... 732s Selecting previously unselected package build-essential. 732s Preparing to unpack .../24-build-essential_12.12ubuntu2_armhf.deb ... 732s Unpacking build-essential (12.12ubuntu2) ... 732s Selecting previously unselected package dctrl-tools. 732s Preparing to unpack .../25-dctrl-tools_2.24-3build4_armhf.deb ... 732s Unpacking dctrl-tools (2.24-3build4) ... 732s Selecting previously unselected package libgfortran-15-dev:armhf. 732s Preparing to unpack .../26-libgfortran-15-dev_15.2.0-12ubuntu1_armhf.deb ... 732s Unpacking libgfortran-15-dev:armhf (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package gfortran-15-arm-linux-gnueabihf. 732s Preparing to unpack .../27-gfortran-15-arm-linux-gnueabihf_15.2.0-12ubuntu1_armhf.deb ... 732s Unpacking gfortran-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package gfortran-15. 732s Preparing to unpack .../28-gfortran-15_15.2.0-12ubuntu1_armhf.deb ... 732s Unpacking gfortran-15 (15.2.0-12ubuntu1) ... 732s Selecting previously unselected package gfortran-arm-linux-gnueabihf. 732s Preparing to unpack .../29-gfortran-arm-linux-gnueabihf_4%3a15.2.0-4ubuntu1_armhf.deb ... 732s Unpacking gfortran-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 732s Selecting previously unselected package gfortran. 733s Preparing to unpack .../30-gfortran_4%3a15.2.0-4ubuntu1_armhf.deb ... 733s Unpacking gfortran (4:15.2.0-4ubuntu1) ... 733s Selecting previously unselected package icu-devtools. 733s Preparing to unpack .../31-icu-devtools_78.2-1ubuntu1_armhf.deb ... 733s Unpacking icu-devtools (78.2-1ubuntu1) ... 733s Selecting previously unselected package libblas-dev:armhf. 733s Preparing to unpack .../32-libblas-dev_3.12.1-7ubuntu1_armhf.deb ... 733s Unpacking libblas-dev:armhf (3.12.1-7ubuntu1) ... 733s Selecting previously unselected package libbz2-dev:armhf. 733s Preparing to unpack .../33-libbz2-dev_1.0.8-6build2_armhf.deb ... 733s Unpacking libbz2-dev:armhf (1.0.8-6build2) ... 733s Selecting previously unselected package libdeflate-dev:armhf. 733s Preparing to unpack .../34-libdeflate-dev_1.23-2build1_armhf.deb ... 733s Unpacking libdeflate-dev:armhf (1.23-2build1) ... 733s Selecting previously unselected package libicu-dev:armhf. 733s Preparing to unpack .../35-libicu-dev_78.2-1ubuntu1_armhf.deb ... 733s Unpacking libicu-dev:armhf (78.2-1ubuntu1) ... 733s Selecting previously unselected package libjpeg-turbo8-dev:armhf. 733s Preparing to unpack .../36-libjpeg-turbo8-dev_2.1.5-4ubuntu3_armhf.deb ... 733s Unpacking libjpeg-turbo8-dev:armhf (2.1.5-4ubuntu3) ... 733s Selecting previously unselected package libjpeg8-dev:armhf. 733s Preparing to unpack .../37-libjpeg8-dev_8c-2ubuntu11_armhf.deb ... 733s Unpacking libjpeg8-dev:armhf (8c-2ubuntu11) ... 733s Selecting previously unselected package libjpeg-dev:armhf. 733s Preparing to unpack .../38-libjpeg-dev_8c-2ubuntu11_armhf.deb ... 733s Unpacking libjpeg-dev:armhf (8c-2ubuntu11) ... 733s Selecting previously unselected package liblapack-dev:armhf. 733s Preparing to unpack .../39-liblapack-dev_3.12.1-7ubuntu1_armhf.deb ... 733s Unpacking liblapack-dev:armhf (3.12.1-7ubuntu1) ... 733s Selecting previously unselected package libncurses-dev:armhf. 733s Preparing to unpack .../40-libncurses-dev_6.6+20251231-1_armhf.deb ... 733s Unpacking libncurses-dev:armhf (6.6+20251231-1) ... 733s Selecting previously unselected package libpcre2-16-0:armhf. 733s Preparing to unpack .../41-libpcre2-16-0_10.46-1_armhf.deb ... 733s Unpacking libpcre2-16-0:armhf (10.46-1) ... 734s Selecting previously unselected package libpcre2-32-0:armhf. 734s Preparing to unpack .../42-libpcre2-32-0_10.46-1_armhf.deb ... 734s Unpacking libpcre2-32-0:armhf (10.46-1) ... 734s Selecting previously unselected package libpcre2-posix3:armhf. 734s Preparing to unpack .../43-libpcre2-posix3_10.46-1_armhf.deb ... 734s Unpacking libpcre2-posix3:armhf (10.46-1) ... 734s Selecting previously unselected package libpcre2-dev:armhf. 734s Preparing to unpack .../44-libpcre2-dev_10.46-1_armhf.deb ... 734s Unpacking libpcre2-dev:armhf (10.46-1) ... 734s Selecting previously unselected package libpkgconf3:armhf. 734s Preparing to unpack .../45-libpkgconf3_1.8.1-4build1_armhf.deb ... 734s Unpacking libpkgconf3:armhf (1.8.1-4build1) ... 734s Selecting previously unselected package zlib1g-dev:armhf. 734s Preparing to unpack .../46-zlib1g-dev_1%3a1.3.dfsg+really1.3.1-1ubuntu2_armhf.deb ... 734s Unpacking zlib1g-dev:armhf (1:1.3.dfsg+really1.3.1-1ubuntu2) ... 734s Selecting previously unselected package libpng-dev:armhf. 734s Preparing to unpack .../47-libpng-dev_1.6.54-1_armhf.deb ... 734s Unpacking libpng-dev:armhf (1.6.54-1) ... 734s Selecting previously unselected package libreadline-dev:armhf. 734s Preparing to unpack .../48-libreadline-dev_8.3-3_armhf.deb ... 734s Unpacking libreadline-dev:armhf (8.3-3) ... 734s Selecting previously unselected package libzstd-dev:armhf. 734s Preparing to unpack .../49-libzstd-dev_1.5.7+dfsg-3_armhf.deb ... 734s Unpacking libzstd-dev:armhf (1.5.7+dfsg-3) ... 734s Selecting previously unselected package liblzma-dev:armhf. 734s Preparing to unpack .../50-liblzma-dev_5.8.2-2_armhf.deb ... 734s Unpacking liblzma-dev:armhf (5.8.2-2) ... 734s Selecting previously unselected package pkgconf-bin. 734s Preparing to unpack .../51-pkgconf-bin_1.8.1-4build1_armhf.deb ... 734s Unpacking pkgconf-bin (1.8.1-4build1) ... 734s Selecting previously unselected package pkgconf:armhf. 734s Preparing to unpack .../52-pkgconf_1.8.1-4build1_armhf.deb ... 734s Unpacking pkgconf:armhf (1.8.1-4build1) ... 734s Selecting previously unselected package libtirpc-dev:armhf. 734s Preparing to unpack .../53-libtirpc-dev_1.3.6+ds-1_armhf.deb ... 734s Unpacking libtirpc-dev:armhf (1.3.6+ds-1) ... 734s Selecting previously unselected package r-base-dev. 734s Preparing to unpack .../54-r-base-dev_4.5.2-1ubuntu2_all.deb ... 734s Unpacking r-base-dev (4.5.2-1ubuntu2) ... 734s Selecting previously unselected package pkg-r-autopkgtest. 734s Preparing to unpack .../55-pkg-r-autopkgtest_20250812_all.deb ... 734s Unpacking pkg-r-autopkgtest (20250812) ... 734s Setting up libzstd-dev:armhf (1.5.7+dfsg-3) ... 734s Setting up linux-libc-dev:armhf (6.19.0-3.3) ... 734s Setting up libpcre2-16-0:armhf (10.46-1) ... 734s Setting up libpcre2-32-0:armhf (10.46-1) ... 734s Setting up libtirpc-dev:armhf (1.3.6+ds-1) ... 734s Setting up libpkgconf3:armhf (1.8.1-4build1) ... 734s Setting up rpcsvc-proto (1.4.3-1build1) ... 734s Setting up libmpc3:armhf (1.3.1-2) ... 734s Setting up icu-devtools (78.2-1ubuntu1) ... 734s Setting up pkgconf-bin (1.8.1-4build1) ... 734s Setting up liblzma-dev:armhf (5.8.2-2) ... 734s Setting up libubsan1:armhf (15.2.0-12ubuntu1) ... 734s Setting up libpcre2-posix3:armhf (10.46-1) ... 734s Setting up libcrypt-dev:armhf (1:4.5.1-1) ... 734s Setting up libasan8:armhf (15.2.0-12ubuntu1) ... 734s Setting up libisl23:armhf (0.27-1build1) ... 734s Setting up libc-dev-bin (2.42-2ubuntu4) ... 734s Setting up libdeflate-dev:armhf (1.23-2build1) ... 734s Setting up cpp-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 734s Setting up libcc1-0:armhf (15.2.0-12ubuntu1) ... 734s Setting up cpp-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 734s Setting up libblas-dev:armhf (3.12.1-7ubuntu1) ... 734s update-alternatives: using /usr/lib/arm-linux-gnueabihf/blas/libblas.so to provide /usr/lib/arm-linux-gnueabihf/libblas.so (libblas.so-arm-linux-gnueabihf) in auto mode 734s Setting up dctrl-tools (2.24-3build4) ... 734s Setting up libgcc-15-dev:armhf (15.2.0-12ubuntu1) ... 734s Setting up gcc-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 734s Setting up libgfortran-15-dev:armhf (15.2.0-12ubuntu1) ... 734s Setting up pkgconf:armhf (1.8.1-4build1) ... 734s Setting up liblapack-dev:armhf (3.12.1-7ubuntu1) ... 734s update-alternatives: using /usr/lib/arm-linux-gnueabihf/lapack/liblapack.so to provide /usr/lib/arm-linux-gnueabihf/liblapack.so (liblapack.so-arm-linux-gnueabihf) in auto mode 734s Setting up cpp-15 (15.2.0-12ubuntu1) ... 734s Setting up cpp (4:15.2.0-4ubuntu1) ... 734s Setting up libc6-dev:armhf (2.42-2ubuntu4) ... 734s Setting up libicu-dev:armhf (78.2-1ubuntu1) ... 734s Setting up libbz2-dev:armhf (1.0.8-6build2) ... 734s Setting up gcc-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 734s Setting up libjpeg-turbo8-dev:armhf (2.1.5-4ubuntu3) ... 734s Setting up libncurses-dev:armhf (6.6+20251231-1) ... 734s Setting up gfortran-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 734s Setting up libpcre2-dev:armhf (10.46-1) ... 734s Setting up libreadline-dev:armhf (8.3-3) ... 734s Setting up gfortran-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 734s Setting up gcc-15 (15.2.0-12ubuntu1) ... 734s Setting up libstdc++-15-dev:armhf (15.2.0-12ubuntu1) ... 734s Setting up zlib1g-dev:armhf (1:1.3.dfsg+really1.3.1-1ubuntu2) ... 734s Setting up libjpeg8-dev:armhf (8c-2ubuntu11) ... 734s Setting up gfortran-15 (15.2.0-12ubuntu1) ... 734s Setting up libpng-dev:armhf (1.6.54-1) ... 734s Setting up libjpeg-dev:armhf (8c-2ubuntu11) ... 734s Setting up g++-15-arm-linux-gnueabihf (15.2.0-12ubuntu1) ... 734s Setting up gcc (4:15.2.0-4ubuntu1) ... 734s Setting up g++-15 (15.2.0-12ubuntu1) ... 734s Setting up g++-arm-linux-gnueabihf (4:15.2.0-4ubuntu1) ... 734s Setting up gfortran (4:15.2.0-4ubuntu1) ... 734s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f95 (f95) in auto mode 734s update-alternatives: warning: skip creation of /usr/share/man/man1/f95.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f95) doesn't exist 734s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f77 (f77) in auto mode 734s update-alternatives: warning: skip creation of /usr/share/man/man1/f77.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f77) doesn't exist 734s Setting up g++ (4:15.2.0-4ubuntu1) ... 734s update-alternatives: using /usr/bin/g++ to provide /usr/bin/c++ (c++) in auto mode 734s Setting up build-essential (12.12ubuntu2) ... 734s Setting up r-base-dev (4.5.2-1ubuntu2) ... 734s Setting up pkg-r-autopkgtest (20250812) ... 734s Processing triggers for libc-bin (2.42-2ubuntu4) ... 734s Processing triggers for man-db (2.13.1-1build1) ... 735s Processing triggers for install-info (7.2-5) ... 743s autopkgtest [23:29:03]: test pkg-r-autopkgtest: /usr/share/dh-r/pkg-r-autopkgtest 743s autopkgtest [23:29:03]: test pkg-r-autopkgtest: [----------------------- 745s Test: Try to load the R library DoseFinding 745s 745s R version 4.5.2 (2025-10-31) -- "[Not] Part in a Rumble" 745s Copyright (C) 2025 The R Foundation for Statistical Computing 745s Platform: arm-unknown-linux-gnueabihf (32-bit) 745s 745s R is free software and comes with ABSOLUTELY NO WARRANTY. 745s You are welcome to redistribute it under certain conditions. 745s Type 'license()' or 'licence()' for distribution details. 745s 745s R is a collaborative project with many contributors. 745s Type 'contributors()' for more information and 745s 'citation()' on how to cite R or R packages in publications. 745s 745s Type 'demo()' for some demos, 'help()' for on-line help, or 745s 'help.start()' for an HTML browser interface to help. 745s Type 'q()' to quit R. 745s 746s > library('DoseFinding') 746s > 747s autopkgtest [23:29:07]: test pkg-r-autopkgtest: -----------------------] 751s pkg-r-autopkgtest PASS 751s autopkgtest [23:29:11]: test pkg-r-autopkgtest: - - - - - - - - - - results - - - - - - - - - - 755s autopkgtest [23:29:15]: @@@@@@@@@@@@@@@@@@@@ summary 755s run-unit-test PASS 755s pkg-r-autopkgtest PASS