0s autopkgtest [23:39:17]: starting date and time: 2026-02-09 23:39:17+0000 0s autopkgtest [23:39:17]: git checkout: 4b346b80 nova: make wait_reboot return success even when a no-op 0s autopkgtest [23:39:17]: host juju-7f2275-prod-proposed-migration-environment-20; command line: /home/ubuntu/autopkgtest/runner/autopkgtest --output-dir /tmp/autopkgtest-work.pnzhej4l/out --timeout-copy=6000 --needs-internet=try --setup-commands /home/ubuntu/autopkgtest-cloud/worker-config-production/setup-canonical.sh --apt-pocket=proposed=src:lattice --apt-upgrade r-cran-dosefinding --timeout-short=300 --timeout-copy=20000 --timeout-build=20000 --env=ADT_TEST_TRIGGERS=lattice/0.22-9-1 -- ssh -s /home/ubuntu/autopkgtest/ssh-setup/nova -- --flavor autopkgtest-cpu2-ram4-disk20-arm64 --security-groups autopkgtest-juju-7f2275-prod-proposed-migration-environment-20@sto01-arm64-6.secgroup --name adt-resolute-arm64-r-cran-dosefinding-20260209-225503-juju-7f2275-prod-proposed-migration-environment-20-3af60885-de28-4aad-b673-5c73c555af77 --image adt/ubuntu-resolute-arm64-server --keyname testbed-juju-7f2275-prod-proposed-migration-environment-20 --net-id=net_prod-autopkgtest-workers-arm64 -e TERM=linux --mirror=http://ftpmaster.internal/ubuntu/ 4s Creating nova instance adt-resolute-arm64-r-cran-dosefinding-20260209-225503-juju-7f2275-prod-proposed-migration-environment-20-3af60885-de28-4aad-b673-5c73c555af77 from image adt/ubuntu-resolute-arm64-server-20260209.img (UUID 793037ca-75af-461b-82de-f8081300b2e3)... 129s autopkgtest [23:41:26]: testbed dpkg architecture: arm64 130s autopkgtest [23:41:27]: testbed apt version: 3.1.15 130s autopkgtest [23:41:27]: @@@@@@@@@@@@@@@@@@@@ test bed setup 130s autopkgtest [23:41:27]: testbed release detected to be: None 131s autopkgtest [23:41:28]: updating testbed package index (apt update) 131s Get:1 http://ftpmaster.internal/ubuntu resolute-proposed InRelease [124 kB] 131s Hit:2 http://ftpmaster.internal/ubuntu resolute InRelease 131s Hit:3 http://ftpmaster.internal/ubuntu resolute-updates InRelease 131s Hit:4 http://ftpmaster.internal/ubuntu resolute-security InRelease 131s Get:5 http://ftpmaster.internal/ubuntu resolute-proposed/universe Sources [1645 kB] 136s Get:6 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse Sources [29.4 kB] 136s Get:7 http://ftpmaster.internal/ubuntu resolute-proposed/main Sources [176 kB] 136s Get:8 http://ftpmaster.internal/ubuntu resolute-proposed/main arm64 Packages [246 kB] 136s Get:9 http://ftpmaster.internal/ubuntu resolute-proposed/main arm64 c-n-f Metadata [6216 B] 136s Get:10 http://ftpmaster.internal/ubuntu resolute-proposed/restricted arm64 c-n-f Metadata [304 B] 136s Get:11 http://ftpmaster.internal/ubuntu resolute-proposed/universe arm64 Packages [1580 kB] 139s Get:12 http://ftpmaster.internal/ubuntu resolute-proposed/universe arm64 c-n-f Metadata [32.0 kB] 139s Get:13 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse arm64 Packages [21.7 kB] 139s Get:14 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse arm64 c-n-f Metadata [688 B] 140s Fetched 3862 kB in 8s (488 kB/s) 141s Reading package lists... 142s Hit:1 http://ftpmaster.internal/ubuntu resolute-proposed InRelease 142s Hit:2 http://ftpmaster.internal/ubuntu resolute InRelease 142s Hit:3 http://ftpmaster.internal/ubuntu resolute-updates InRelease 142s Hit:4 http://ftpmaster.internal/ubuntu resolute-security InRelease 143s Reading package lists... 143s Reading package lists... 143s Building dependency tree... 143s Reading state information... 143s Calculating upgrade... 144s The following packages will be upgraded: 144s cryptsetup-bin dracut-install iproute2 iptables libcryptsetup12 libip4tc2 144s libip6tc2 libxtables12 wget 144s 9 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 144s Need to get 2534 kB of archives. 144s After this operation, 18.4 kB of additional disk space will be used. 144s Get:1 http://ftpmaster.internal/ubuntu resolute/main arm64 iptables arm64 1.8.11-2ubuntu3 [386 kB] 144s Get:2 http://ftpmaster.internal/ubuntu resolute/main arm64 libip4tc2 arm64 1.8.11-2ubuntu3 [24.3 kB] 144s Get:3 http://ftpmaster.internal/ubuntu resolute/main arm64 libip6tc2 arm64 1.8.11-2ubuntu3 [24.7 kB] 144s Get:4 http://ftpmaster.internal/ubuntu resolute/main arm64 libxtables12 arm64 1.8.11-2ubuntu3 [36.7 kB] 144s Get:5 http://ftpmaster.internal/ubuntu resolute/main arm64 iproute2 arm64 6.18.0-1ubuntu1 [1171 kB] 146s Get:6 http://ftpmaster.internal/ubuntu resolute/main arm64 libcryptsetup12 arm64 2:2.8.0-1ubuntu3 [274 kB] 146s Get:7 http://ftpmaster.internal/ubuntu resolute/main arm64 wget arm64 1.25.0-2ubuntu4 [344 kB] 146s Get:8 http://ftpmaster.internal/ubuntu resolute/main arm64 cryptsetup-bin arm64 2:2.8.0-1ubuntu3 [227 kB] 146s Get:9 http://ftpmaster.internal/ubuntu resolute/main arm64 dracut-install arm64 109-11ubuntu1 [45.3 kB] 146s dpkg-preconfigure: unable to re-open stdin: No such file or directory 146s Fetched 2534 kB in 2s (1096 kB/s) 147s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 136597 files and directories currently installed.) 147s Preparing to unpack .../0-iptables_1.8.11-2ubuntu3_arm64.deb ... 147s Unpacking iptables (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 147s Preparing to unpack .../1-libip4tc2_1.8.11-2ubuntu3_arm64.deb ... 147s Unpacking libip4tc2:arm64 (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 147s Preparing to unpack .../2-libip6tc2_1.8.11-2ubuntu3_arm64.deb ... 147s Unpacking libip6tc2:arm64 (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 147s Preparing to unpack .../3-libxtables12_1.8.11-2ubuntu3_arm64.deb ... 147s Unpacking libxtables12:arm64 (1.8.11-2ubuntu3) over (1.8.11-2ubuntu2) ... 147s Preparing to unpack .../4-iproute2_6.18.0-1ubuntu1_arm64.deb ... 147s Unpacking iproute2 (6.18.0-1ubuntu1) over (6.16.0-1ubuntu3) ... 147s Preparing to unpack .../5-libcryptsetup12_2%3a2.8.0-1ubuntu3_arm64.deb ... 147s Unpacking libcryptsetup12:arm64 (2:2.8.0-1ubuntu3) over (2:2.8.0-1ubuntu2) ... 147s Preparing to unpack .../6-wget_1.25.0-2ubuntu4_arm64.deb ... 147s Unpacking wget (1.25.0-2ubuntu4) over (1.25.0-2ubuntu3) ... 147s Preparing to unpack .../7-cryptsetup-bin_2%3a2.8.0-1ubuntu3_arm64.deb ... 147s Unpacking cryptsetup-bin (2:2.8.0-1ubuntu3) over (2:2.8.0-1ubuntu2) ... 148s Preparing to unpack .../8-dracut-install_109-11ubuntu1_arm64.deb ... 148s Unpacking dracut-install (109-11ubuntu1) over (109-9ubuntu1) ... 148s Setting up libip4tc2:arm64 (1.8.11-2ubuntu3) ... 148s Setting up wget (1.25.0-2ubuntu4) ... 148s Setting up libip6tc2:arm64 (1.8.11-2ubuntu3) ... 148s Setting up libxtables12:arm64 (1.8.11-2ubuntu3) ... 148s Setting up dracut-install (109-11ubuntu1) ... 148s Setting up libcryptsetup12:arm64 (2:2.8.0-1ubuntu3) ... 148s Setting up cryptsetup-bin (2:2.8.0-1ubuntu3) ... 148s Setting up iptables (1.8.11-2ubuntu3) ... 148s Setting up iproute2 (6.18.0-1ubuntu1) ... 148s Processing triggers for man-db (2.13.1-1build1) ... 149s Processing triggers for install-info (7.2-5) ... 149s Processing triggers for libc-bin (2.42-2ubuntu4) ... 149s autopkgtest [23:41:46]: upgrading testbed (apt dist-upgrade and autopurge) 150s Reading package lists... 150s Building dependency tree... 150s Reading state information... 150s Calculating upgrade... 150s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 150s Reading package lists... 151s Building dependency tree... 151s Reading state information... 151s Solving dependencies... 151s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 153s autopkgtest [23:41:50]: testbed running kernel: Linux 6.19.0-3-generic #3-Ubuntu SMP PREEMPT_DYNAMIC Fri Jan 23 19:46:27 UTC 2026 154s autopkgtest [23:41:51]: @@@@@@@@@@@@@@@@@@@@ apt-source r-cran-dosefinding 157s Get:1 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (dsc) [2322 B] 157s Get:2 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (tar) [698 kB] 157s Get:3 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (diff) [4244 B] 157s gpgv: Signature made Fri Mar 14 00:07:33 2025 UTC 157s gpgv: using RSA key 73471499CC60ED9EEE805946C5BD6C8F2295D502 157s gpgv: issuer "plessy@debian.org" 157s gpgv: Can't check signature: No public key 157s dpkg-source: warning: cannot verify inline signature for ./r-cran-dosefinding_1.3-1-1.dsc: no acceptable signature found 157s autopkgtest [23:41:54]: testing package r-cran-dosefinding version 1.3-1-1 158s autopkgtest [23:41:55]: build not needed 159s autopkgtest [23:41:56]: test run-unit-test: preparing testbed 159s Reading package lists... 160s Building dependency tree... 160s Reading state information... 160s Solving dependencies... 160s The following NEW packages will be installed: 160s fontconfig fontconfig-config fonts-dejavu-core fonts-dejavu-mono 160s fonts-font-awesome fonts-glyphicons-halflings fonts-mathjax 160s javascript-common libblas3 libcairo2 libdatrie1 libdeflate0 libfontconfig1 160s libgfortran5 libgomp1 libgraphite2-3 libharfbuzz0b libice6 libjbig0 160s libjpeg-turbo8 libjpeg8 libjs-bootstrap libjs-bootstrap4 libjs-d3 160s libjs-es5-shim libjs-highlight.js libjs-jquery libjs-jquery-datatables 160s libjs-jquery-selectize.js libjs-jquery-ui libjs-json libjs-mathjax 160s libjs-microplugin.js libjs-modernizr libjs-popper.js libjs-prettify 160s libjs-sifter.js libjs-twitter-bootstrap-datepicker liblapack3 liblerc4 160s liblua5.4-0 libpango-1.0-0 libpangocairo-1.0-0 libpangoft2-1.0-0 160s libpaper-utils libpaper2 libpixman-1-0 libsharpyuv0 libsm6 libtcl8.6 160s libthai-data libthai0 libtiff6 libtk8.6 libwebp7 libxcb-render0 libxcb-shm0 160s libxft2 libxrender1 libxss1 libxt6t64 node-bootstrap-sass node-html5shiv 160s node-normalize.css pandoc pandoc-data r-base-core r-cran-base64enc 160s r-cran-brio r-cran-bslib r-cran-cachem r-cran-callr r-cran-cli 160s r-cran-codetools r-cran-commonmark r-cran-crayon r-cran-desc r-cran-diffobj 160s r-cran-digest r-cran-dosefinding r-cran-evaluate r-cran-fansi r-cran-farver 160s r-cran-fastmap r-cran-fontawesome r-cran-fs r-cran-ggplot2 r-cran-glue 160s r-cran-gtable r-cran-highr r-cran-htmltools r-cran-httpuv r-cran-isoband 160s r-cran-jquerylib r-cran-jsonlite r-cran-knitr r-cran-labeling r-cran-later 160s r-cran-lattice r-cran-lifecycle r-cran-littler r-cran-magrittr r-cran-mass 160s r-cran-matrix r-cran-memoise r-cran-mgcv r-cran-mime r-cran-multcomp 160s r-cran-mvtnorm r-cran-nlme r-cran-numderiv r-cran-pillar r-cran-pkgbuild 160s r-cran-pkgconfig r-cran-pkgkitten r-cran-pkgload r-cran-praise 160s r-cran-processx r-cran-promises r-cran-ps r-cran-quadprog r-cran-r6 160s r-cran-rappdirs r-cran-rcolorbrewer r-cran-rcpp r-cran-rlang 160s r-cran-rmarkdown r-cran-rprojroot r-cran-rsolnp r-cran-sandwich r-cran-sass 160s r-cran-scales r-cran-shiny r-cran-sourcetools r-cran-survival 160s r-cran-testthat r-cran-th.data r-cran-tibble r-cran-tinytex r-cran-truncnorm 160s r-cran-utf8 r-cran-vctrs r-cran-viridislite r-cran-waldo r-cran-withr 160s r-cran-xfun r-cran-xtable r-cran-yaml r-cran-zoo unzip x11-common xdg-utils 160s zip 160s 0 upgraded, 153 newly installed, 0 to remove and 0 not upgraded. 160s Need to get 153 MB of archives. 160s After this operation, 484 MB of additional disk space will be used. 160s Get:1 http://ftpmaster.internal/ubuntu resolute/main arm64 fonts-dejavu-mono all 2.37-8build1 [502 kB] 161s Get:2 http://ftpmaster.internal/ubuntu resolute/main arm64 fonts-dejavu-core all 2.37-8build1 [834 kB] 163s Get:3 http://ftpmaster.internal/ubuntu resolute/main arm64 fontconfig-config arm64 2.17.1-3ubuntu1 [38.5 kB] 163s Get:4 http://ftpmaster.internal/ubuntu resolute/main arm64 libfontconfig1 arm64 2.17.1-3ubuntu1 [144 kB] 163s Get:5 http://ftpmaster.internal/ubuntu resolute/main arm64 fontconfig arm64 2.17.1-3ubuntu1 [181 kB] 163s Get:6 http://ftpmaster.internal/ubuntu resolute/main arm64 fonts-font-awesome all 5.0.10+really4.7.0~dfsg-4.1build1 [531 kB] 164s Get:7 http://ftpmaster.internal/ubuntu resolute/universe arm64 fonts-glyphicons-halflings all 1.009~3.4.1+dfsg-6 [119 kB] 164s Get:8 http://ftpmaster.internal/ubuntu resolute/main arm64 fonts-mathjax all 2.7.9+dfsg-1build1 [2283 kB] 170s Get:9 http://ftpmaster.internal/ubuntu resolute/main arm64 javascript-common all 12+nmu1build1 [4864 B] 170s Get:10 http://ftpmaster.internal/ubuntu resolute/main arm64 libblas3 arm64 3.12.1-7ubuntu1 [181 kB] 170s Get:11 http://ftpmaster.internal/ubuntu resolute/main arm64 libpixman-1-0 arm64 0.46.4-1 [204 kB] 170s Get:12 http://ftpmaster.internal/ubuntu resolute/main arm64 libxcb-render0 arm64 1.17.0-2ubuntu1 [16.4 kB] 170s Get:13 http://ftpmaster.internal/ubuntu resolute/main arm64 libxcb-shm0 arm64 1.17.0-2ubuntu1 [5938 B] 170s Get:14 http://ftpmaster.internal/ubuntu resolute/main arm64 libxrender1 arm64 1:0.9.12-1 [19.5 kB] 170s Get:15 http://ftpmaster.internal/ubuntu resolute/main arm64 libcairo2 arm64 1.18.4-3 [556 kB] 171s Get:16 http://ftpmaster.internal/ubuntu resolute/main arm64 libdatrie1 arm64 0.2.14-1 [19.6 kB] 171s Get:17 http://ftpmaster.internal/ubuntu resolute/main arm64 libdeflate0 arm64 1.23-2build1 [46.8 kB] 171s Get:18 http://ftpmaster.internal/ubuntu resolute/main arm64 libgfortran5 arm64 15.2.0-12ubuntu1 [451 kB] 171s Get:19 http://ftpmaster.internal/ubuntu resolute/main arm64 libgomp1 arm64 15.2.0-12ubuntu1 [147 kB] 171s Get:20 http://ftpmaster.internal/ubuntu resolute/main arm64 libgraphite2-3 arm64 1.3.14-11ubuntu1 [72.1 kB] 171s Get:21 http://ftpmaster.internal/ubuntu resolute/main arm64 libharfbuzz0b arm64 12.3.2-1 [510 kB] 171s Get:22 http://ftpmaster.internal/ubuntu resolute/main arm64 x11-common all 1:7.7+24ubuntu1 [22.4 kB] 171s Get:23 http://ftpmaster.internal/ubuntu resolute/main arm64 libice6 arm64 2:1.1.1-1build1 [43.0 kB] 171s Get:24 http://ftpmaster.internal/ubuntu resolute/main arm64 libjpeg-turbo8 arm64 2.1.5-4ubuntu3 [161 kB] 171s Get:25 http://ftpmaster.internal/ubuntu resolute/main arm64 libjpeg8 arm64 8c-2ubuntu11 [2148 B] 171s Get:26 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-bootstrap all 3.4.1+dfsg-6 [129 kB] 171s Get:27 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-popper.js all 1.16.1+ds-6build1 [53.8 kB] 171s Get:28 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-bootstrap4 all 4.6.2+dfsg-1 [532 kB] 172s Get:29 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-d3 all 3.5.17-4build1 [136 kB] 172s Get:30 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-es5-shim all 4.6.7-2 [39.8 kB] 172s Get:31 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-highlight.js all 10.7.3+dfsg-2 [144 kB] 172s Get:32 http://ftpmaster.internal/ubuntu resolute/main arm64 libjs-jquery all 3.7.1+dfsg+~3.5.33-1build1 [321 kB] 172s Get:33 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-jquery-datatables all 1.11.5+dfsg-2build1 [145 kB] 172s Get:34 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-sifter.js all 0.6.0+dfsg-3 [12.6 kB] 172s Get:35 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-microplugin.js all 0.0.3+dfsg-2 [3946 B] 172s Get:36 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-jquery-selectize.js all 0.12.6+dfsg-1.1 [51.0 kB] 172s Get:37 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-jquery-ui all 1.13.2+dfsg-1build1 [251 kB] 172s Get:38 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-json all 0~20221030+~1.0.8-1build1 [20.6 kB] 172s Get:39 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-prettify all 2015.12.04+dfsg-3 [41.4 kB] 172s Get:40 http://ftpmaster.internal/ubuntu resolute/main arm64 liblapack3 arm64 3.12.1-7ubuntu1 [2299 kB] 177s Get:41 http://ftpmaster.internal/ubuntu resolute/main arm64 liblerc4 arm64 4.0.0+ds-5ubuntu2 [174 kB] 177s Get:42 http://ftpmaster.internal/ubuntu resolute/main arm64 liblua5.4-0 arm64 5.4.8-1 [171 kB] 177s Get:43 http://ftpmaster.internal/ubuntu resolute/main arm64 libthai-data all 0.1.30-1 [155 kB] 177s Get:44 http://ftpmaster.internal/ubuntu resolute/main arm64 libthai0 arm64 0.1.30-1 [18.3 kB] 177s Get:45 http://ftpmaster.internal/ubuntu resolute/main arm64 libpango-1.0-0 arm64 1.57.0-1 [238 kB] 177s Get:46 http://ftpmaster.internal/ubuntu resolute/main arm64 libpangoft2-1.0-0 arm64 1.57.0-1 [51.5 kB] 177s Get:47 http://ftpmaster.internal/ubuntu resolute/main arm64 libpangocairo-1.0-0 arm64 1.57.0-1 [27.9 kB] 177s Get:48 http://ftpmaster.internal/ubuntu resolute/main arm64 libpaper2 arm64 2.2.5-0.3build1 [17.3 kB] 177s Get:49 http://ftpmaster.internal/ubuntu resolute/main arm64 libpaper-utils arm64 2.2.5-0.3build1 [15.4 kB] 177s Get:50 http://ftpmaster.internal/ubuntu resolute/main arm64 libsharpyuv0 arm64 1.5.0-0.1build1 [16.7 kB] 177s Get:51 http://ftpmaster.internal/ubuntu resolute/main arm64 libsm6 arm64 2:1.2.6-1build1 [16.8 kB] 177s Get:52 http://ftpmaster.internal/ubuntu resolute/main arm64 libtcl8.6 arm64 8.6.17+dfsg-1build1 [983 kB] 179s Get:53 http://ftpmaster.internal/ubuntu resolute/main arm64 libjbig0 arm64 2.1-6.1ubuntu3 [29.2 kB] 179s Get:54 http://ftpmaster.internal/ubuntu resolute/main arm64 libwebp7 arm64 1.5.0-0.1build1 [205 kB] 179s Get:55 http://ftpmaster.internal/ubuntu resolute/main arm64 libtiff6 arm64 4.7.0-3ubuntu3 [196 kB] 179s Get:56 http://ftpmaster.internal/ubuntu resolute/main arm64 libxft2 arm64 2.3.6-1build2 [43.2 kB] 179s Get:57 http://ftpmaster.internal/ubuntu resolute/main arm64 libxss1 arm64 1:1.2.3-1build4 [7102 B] 179s Get:58 http://ftpmaster.internal/ubuntu resolute/main arm64 libtk8.6 arm64 8.6.17-1 [811 kB] 180s Get:59 http://ftpmaster.internal/ubuntu resolute/main arm64 libxt6t64 arm64 1:1.2.1-1.3 [168 kB] 181s Get:60 http://ftpmaster.internal/ubuntu resolute/universe arm64 node-bootstrap-sass all 3.4.3-2 [187 kB] 181s Get:61 http://ftpmaster.internal/ubuntu resolute/universe arm64 node-html5shiv all 3.7.3+dfsg-5 [13.5 kB] 181s Get:62 http://ftpmaster.internal/ubuntu resolute/universe arm64 node-normalize.css all 8.0.1-5.1 [10.4 kB] 181s Get:63 http://ftpmaster.internal/ubuntu resolute/universe arm64 pandoc-data all 3.1.11.1-3build1 [78.8 kB] 181s Get:64 http://ftpmaster.internal/ubuntu resolute/universe arm64 pandoc arm64 3.1.11.1+ds-4 [28.0 MB] 233s Get:65 http://ftpmaster.internal/ubuntu resolute/main arm64 zip arm64 3.0-15ubuntu3 [170 kB] 233s Get:66 http://ftpmaster.internal/ubuntu resolute/main arm64 unzip arm64 6.0-29ubuntu1 [176 kB] 233s Get:67 http://ftpmaster.internal/ubuntu resolute/main arm64 xdg-utils all 1.2.1-2ubuntu2 [66.1 kB] 233s Get:68 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-base-core arm64 4.5.2-1ubuntu2 [28.6 MB] 286s Get:69 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-base64enc arm64 0.1-3-3build1 [28.5 kB] 286s Get:70 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-brio arm64 1.1.5-1 [39.1 kB] 286s Get:71 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rlang arm64 1.1.5-3 [1706 kB] 289s Get:72 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-fastmap arm64 1.2.0-1 [70.6 kB] 289s Get:73 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-cachem arm64 1.1.0-1 [74.1 kB] 289s Get:74 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-digest arm64 0.6.39-1 [196 kB] 289s Get:75 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-htmltools arm64 0.5.8.1-1 [373 kB] 289s Get:76 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-jquerylib all 0.1.4+dfsg-5 [13.7 kB] 289s Get:77 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-jsonlite arm64 1.9.1+dfsg-1 [445 kB] 289s Get:78 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-cli arm64 3.6.4-1 [1374 kB] 292s Get:79 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-lifecycle all 1.0.5+dfsg-1 [120 kB] 292s Get:80 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-memoise all 2.0.1-1build1 [54.5 kB] 292s Get:81 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-mime arm64 0.12-2 [35.8 kB] 292s Get:82 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-fs arm64 1.6.5+dfsg-1 [244 kB] 292s Get:83 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-r6 all 2.6.1-1 [101 kB] 292s Get:84 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rappdirs arm64 0.3.3-1build1 [49.5 kB] 292s Get:85 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-sass arm64 0.4.9+dfsg-1 [957 kB] 294s Get:86 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-bslib all 0.9.0+dfsg-3build1 [4560 kB] 302s Get:87 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-ps arm64 1.9.0-1 [407 kB] 302s Get:88 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-processx arm64 3.8.6-1 [363 kB] 302s Get:89 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-callr all 3.7.6-1 [458 kB] 302s Get:90 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-codetools all 0.2-20-1build1 [91.1 kB] 302s Get:91 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-commonmark arm64 1.9.5-1 [130 kB] 302s Get:92 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-crayon all 1.5.3-1 [165 kB] 302s Get:93 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-desc all 1.4.3-1 [359 kB] 302s Get:94 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-diffobj arm64 0.3.5-1build1 [1154 kB] 304s Get:95 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-glue arm64 1.8.0-1 [163 kB] 304s Get:96 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-gtable all 0.3.6+dfsg-1 [199 kB] 304s Get:97 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-isoband arm64 0.2.7-1 [1481 kB] 308s Get:98 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-mass arm64 7.3-65-1 [1109 kB] 310s Get:99 http://ftpmaster.internal/ubuntu resolute-proposed/universe arm64 r-cran-lattice arm64 0.22-9-1 [1399 kB] 313s Get:100 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-nlme arm64 3.1.168-1 [2310 kB] 317s Get:101 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-matrix arm64 1.7-4-1 [4146 kB] 324s Get:102 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-mgcv arm64 1.9-4-1 [3546 kB] 330s Get:103 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-farver arm64 2.1.2-1 [1344 kB] 334s Get:104 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-labeling all 0.4.3-1 [62.1 kB] 334s Get:105 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rcolorbrewer all 1.1-3-1build2 [54.0 kB] 334s Get:106 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-viridislite all 0.4.3-1 [1088 kB] 337s Get:107 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-scales all 1.4.0-1 [725 kB] 338s Get:108 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-fansi arm64 1.0.6-2 [627 kB] 339s Get:109 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-magrittr arm64 2.0.3-1 [154 kB] 339s Get:110 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-utf8 arm64 1.2.4-1 [140 kB] 339s Get:111 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-vctrs arm64 0.6.5-1 [1327 kB] 341s Get:112 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-pillar all 1.11.1+dfsg-1 [456 kB] 341s Get:113 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-pkgconfig all 2.0.3-2build2 [20.4 kB] 341s Get:114 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-tibble arm64 3.2.1+dfsg-3 [420 kB] 341s Get:115 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-withr all 3.0.2+dfsg-1 [214 kB] 341s Get:116 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-ggplot2 all 3.5.1+dfsg-1 [3940 kB] 349s Get:117 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-mvtnorm arm64 1.3-3-1build1 [919 kB] 351s Get:118 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-dosefinding arm64 1.3-1-1 [973 kB] 353s Get:119 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-evaluate all 1.0.5-1 [117 kB] 353s Get:120 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-fontawesome all 0.5.3-1 [1331 kB] 356s Get:121 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-xfun arm64 0.55+dfsg-1 [587 kB] 357s Get:122 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-highr all 0.11+dfsg-1 [38.5 kB] 357s Get:123 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-littler arm64 0.3.22-1 [85.1 kB] 357s Get:124 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-pkgkitten all 0.2.4-1 [27.2 kB] 357s Get:125 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rcpp arm64 1.1.0-1 [2011 kB] 361s Get:126 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-later arm64 1.4.1+dfsg-1 [141 kB] 361s Get:127 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-promises arm64 1.3.2+dfsg-1 [290 kB] 361s Get:128 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-httpuv arm64 1.6.15+dfsg-1 [489 kB] 361s Get:129 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-yaml arm64 2.3.10-1 [108 kB] 361s Get:130 http://ftpmaster.internal/ubuntu resolute/main arm64 libjs-mathjax all 2.7.9+dfsg-1build1 [6017 kB] 372s Get:131 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-knitr all 1.51+dfsg-1 [847 kB] 374s Get:132 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-survival arm64 3.8-6-1 [8270 kB] 400s Get:133 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-th.data all 1.1-5-1 [8740 kB] 416s Get:134 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-zoo arm64 1.8-15-1 [1025 kB] 418s Get:135 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-sandwich all 3.1-1-1build1 [1483 kB] 421s Get:136 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-multcomp all 1.4-29-1 [617 kB] 422s Get:137 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-numderiv all 2016.8-1.1-3build1 [116 kB] 422s Get:138 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-pkgbuild all 1.4.8-1 [219 kB] 422s Get:139 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rprojroot all 2.1.1-1 [131 kB] 422s Get:140 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-pkgload all 1.4.1-1 [252 kB] 422s Get:141 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-praise all 1.0.0-4build2 [20.9 kB] 422s Get:142 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-quadprog arm64 1.5-8-1build2 [31.9 kB] 422s Get:143 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-tinytex all 0.58-1 [148 kB] 422s Get:144 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-modernizr all 3.13.0-0.1build1 [100 kB] 422s Get:145 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-xtable all 1:1.8-4-2build1 [691 kB] 423s Get:146 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-sourcetools arm64 0.1.7-1-1 [47.2 kB] 423s Get:147 http://ftpmaster.internal/ubuntu resolute/universe arm64 libjs-twitter-bootstrap-datepicker all 1.3.1+dfsg1-4.1 [28.5 kB] 424s Get:148 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-shiny all 1.10.0+dfsg-2 [3124 kB] 430s Get:149 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rmarkdown all 2.30+dfsg-1 [1501 kB] 434s Get:150 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-truncnorm arm64 1.0-9-2 [24.9 kB] 434s Get:151 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-rsolnp all 1.16+dfsg-4build2 [248 kB] 434s Get:152 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-waldo all 0.6.2-1 [153 kB] 434s Get:153 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-cran-testthat arm64 3.2.3-1 [1644 kB] 438s Preconfiguring packages ... 438s Fetched 153 MB in 4min 37s (552 kB/s) 438s Selecting previously unselected package fonts-dejavu-mono. 438s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 136600 files and directories currently installed.) 438s Preparing to unpack .../000-fonts-dejavu-mono_2.37-8build1_all.deb ... 438s Unpacking fonts-dejavu-mono (2.37-8build1) ... 438s Selecting previously unselected package fonts-dejavu-core. 438s Preparing to unpack .../001-fonts-dejavu-core_2.37-8build1_all.deb ... 438s Unpacking fonts-dejavu-core (2.37-8build1) ... 438s Selecting previously unselected package fontconfig-config. 438s Preparing to unpack .../002-fontconfig-config_2.17.1-3ubuntu1_arm64.deb ... 438s Unpacking fontconfig-config (2.17.1-3ubuntu1) ... 438s Selecting previously unselected package libfontconfig1:arm64. 438s Preparing to unpack .../003-libfontconfig1_2.17.1-3ubuntu1_arm64.deb ... 438s Unpacking libfontconfig1:arm64 (2.17.1-3ubuntu1) ... 438s Selecting previously unselected package fontconfig. 438s Preparing to unpack .../004-fontconfig_2.17.1-3ubuntu1_arm64.deb ... 438s Unpacking fontconfig (2.17.1-3ubuntu1) ... 438s Selecting previously unselected package fonts-font-awesome. 438s Preparing to unpack .../005-fonts-font-awesome_5.0.10+really4.7.0~dfsg-4.1build1_all.deb ... 438s Unpacking fonts-font-awesome (5.0.10+really4.7.0~dfsg-4.1build1) ... 438s Selecting previously unselected package fonts-glyphicons-halflings. 438s Preparing to unpack .../006-fonts-glyphicons-halflings_1.009~3.4.1+dfsg-6_all.deb ... 438s Unpacking fonts-glyphicons-halflings (1.009~3.4.1+dfsg-6) ... 438s Selecting previously unselected package fonts-mathjax. 438s Preparing to unpack .../007-fonts-mathjax_2.7.9+dfsg-1build1_all.deb ... 438s Unpacking fonts-mathjax (2.7.9+dfsg-1build1) ... 438s Selecting previously unselected package javascript-common. 438s Preparing to unpack .../008-javascript-common_12+nmu1build1_all.deb ... 438s Unpacking javascript-common (12+nmu1build1) ... 438s Selecting previously unselected package libblas3:arm64. 438s Preparing to unpack .../009-libblas3_3.12.1-7ubuntu1_arm64.deb ... 438s Unpacking libblas3:arm64 (3.12.1-7ubuntu1) ... 438s Selecting previously unselected package libpixman-1-0:arm64. 439s Preparing to unpack .../010-libpixman-1-0_0.46.4-1_arm64.deb ... 439s Unpacking libpixman-1-0:arm64 (0.46.4-1) ... 439s Selecting previously unselected package libxcb-render0:arm64. 439s Preparing to unpack .../011-libxcb-render0_1.17.0-2ubuntu1_arm64.deb ... 439s Unpacking libxcb-render0:arm64 (1.17.0-2ubuntu1) ... 439s Selecting previously unselected package libxcb-shm0:arm64. 439s Preparing to unpack .../012-libxcb-shm0_1.17.0-2ubuntu1_arm64.deb ... 439s Unpacking libxcb-shm0:arm64 (1.17.0-2ubuntu1) ... 439s Selecting previously unselected package libxrender1:arm64. 439s Preparing to unpack .../013-libxrender1_1%3a0.9.12-1_arm64.deb ... 439s Unpacking libxrender1:arm64 (1:0.9.12-1) ... 439s Selecting previously unselected package libcairo2:arm64. 439s Preparing to unpack .../014-libcairo2_1.18.4-3_arm64.deb ... 439s Unpacking libcairo2:arm64 (1.18.4-3) ... 439s Selecting previously unselected package libdatrie1:arm64. 439s Preparing to unpack .../015-libdatrie1_0.2.14-1_arm64.deb ... 439s Unpacking libdatrie1:arm64 (0.2.14-1) ... 439s Selecting previously unselected package libdeflate0:arm64. 439s Preparing to unpack .../016-libdeflate0_1.23-2build1_arm64.deb ... 439s Unpacking libdeflate0:arm64 (1.23-2build1) ... 439s Selecting previously unselected package libgfortran5:arm64. 439s Preparing to unpack .../017-libgfortran5_15.2.0-12ubuntu1_arm64.deb ... 439s Unpacking libgfortran5:arm64 (15.2.0-12ubuntu1) ... 439s Selecting previously unselected package libgomp1:arm64. 439s Preparing to unpack .../018-libgomp1_15.2.0-12ubuntu1_arm64.deb ... 439s Unpacking libgomp1:arm64 (15.2.0-12ubuntu1) ... 439s Selecting previously unselected package libgraphite2-3:arm64. 439s Preparing to unpack .../019-libgraphite2-3_1.3.14-11ubuntu1_arm64.deb ... 439s Unpacking libgraphite2-3:arm64 (1.3.14-11ubuntu1) ... 439s Selecting previously unselected package libharfbuzz0b:arm64. 439s Preparing to unpack .../020-libharfbuzz0b_12.3.2-1_arm64.deb ... 439s Unpacking libharfbuzz0b:arm64 (12.3.2-1) ... 439s Selecting previously unselected package x11-common. 439s Preparing to unpack .../021-x11-common_1%3a7.7+24ubuntu1_all.deb ... 439s Unpacking x11-common (1:7.7+24ubuntu1) ... 439s Selecting previously unselected package libice6:arm64. 439s Preparing to unpack .../022-libice6_2%3a1.1.1-1build1_arm64.deb ... 439s Unpacking libice6:arm64 (2:1.1.1-1build1) ... 439s Selecting previously unselected package libjpeg-turbo8:arm64. 439s Preparing to unpack .../023-libjpeg-turbo8_2.1.5-4ubuntu3_arm64.deb ... 439s Unpacking libjpeg-turbo8:arm64 (2.1.5-4ubuntu3) ... 439s Selecting previously unselected package libjpeg8:arm64. 439s Preparing to unpack .../024-libjpeg8_8c-2ubuntu11_arm64.deb ... 439s Unpacking libjpeg8:arm64 (8c-2ubuntu11) ... 439s Selecting previously unselected package libjs-bootstrap. 439s Preparing to unpack .../025-libjs-bootstrap_3.4.1+dfsg-6_all.deb ... 439s Unpacking libjs-bootstrap (3.4.1+dfsg-6) ... 439s Selecting previously unselected package libjs-popper.js. 439s Preparing to unpack .../026-libjs-popper.js_1.16.1+ds-6build1_all.deb ... 439s Unpacking libjs-popper.js (1.16.1+ds-6build1) ... 439s Selecting previously unselected package libjs-bootstrap4. 439s Preparing to unpack .../027-libjs-bootstrap4_4.6.2+dfsg-1_all.deb ... 439s Unpacking libjs-bootstrap4 (4.6.2+dfsg-1) ... 439s Selecting previously unselected package libjs-d3. 439s Preparing to unpack .../028-libjs-d3_3.5.17-4build1_all.deb ... 439s Unpacking libjs-d3 (3.5.17-4build1) ... 439s Selecting previously unselected package libjs-es5-shim. 439s Preparing to unpack .../029-libjs-es5-shim_4.6.7-2_all.deb ... 439s Unpacking libjs-es5-shim (4.6.7-2) ... 439s Selecting previously unselected package libjs-highlight.js. 439s Preparing to unpack .../030-libjs-highlight.js_10.7.3+dfsg-2_all.deb ... 439s Unpacking libjs-highlight.js (10.7.3+dfsg-2) ... 439s Selecting previously unselected package libjs-jquery. 439s Preparing to unpack .../031-libjs-jquery_3.7.1+dfsg+~3.5.33-1build1_all.deb ... 439s Unpacking libjs-jquery (3.7.1+dfsg+~3.5.33-1build1) ... 439s Selecting previously unselected package libjs-jquery-datatables. 439s Preparing to unpack .../032-libjs-jquery-datatables_1.11.5+dfsg-2build1_all.deb ... 439s Unpacking libjs-jquery-datatables (1.11.5+dfsg-2build1) ... 439s Selecting previously unselected package libjs-sifter.js. 439s Preparing to unpack .../033-libjs-sifter.js_0.6.0+dfsg-3_all.deb ... 439s Unpacking libjs-sifter.js (0.6.0+dfsg-3) ... 439s Selecting previously unselected package libjs-microplugin.js. 440s Preparing to unpack .../034-libjs-microplugin.js_0.0.3+dfsg-2_all.deb ... 440s Unpacking libjs-microplugin.js (0.0.3+dfsg-2) ... 440s Selecting previously unselected package libjs-jquery-selectize.js. 440s Preparing to unpack .../035-libjs-jquery-selectize.js_0.12.6+dfsg-1.1_all.deb ... 440s Unpacking libjs-jquery-selectize.js (0.12.6+dfsg-1.1) ... 440s Selecting previously unselected package libjs-jquery-ui. 440s Preparing to unpack .../036-libjs-jquery-ui_1.13.2+dfsg-1build1_all.deb ... 440s Unpacking libjs-jquery-ui (1.13.2+dfsg-1build1) ... 440s Selecting previously unselected package libjs-json. 440s Preparing to unpack .../037-libjs-json_0~20221030+~1.0.8-1build1_all.deb ... 440s Unpacking libjs-json (0~20221030+~1.0.8-1build1) ... 440s Selecting previously unselected package libjs-prettify. 440s Preparing to unpack .../038-libjs-prettify_2015.12.04+dfsg-3_all.deb ... 440s Unpacking libjs-prettify (2015.12.04+dfsg-3) ... 440s Selecting previously unselected package liblapack3:arm64. 440s Preparing to unpack .../039-liblapack3_3.12.1-7ubuntu1_arm64.deb ... 440s Unpacking liblapack3:arm64 (3.12.1-7ubuntu1) ... 440s Selecting previously unselected package liblerc4:arm64. 440s Preparing to unpack .../040-liblerc4_4.0.0+ds-5ubuntu2_arm64.deb ... 440s Unpacking liblerc4:arm64 (4.0.0+ds-5ubuntu2) ... 440s Selecting previously unselected package liblua5.4-0:arm64. 440s Preparing to unpack .../041-liblua5.4-0_5.4.8-1_arm64.deb ... 440s Unpacking liblua5.4-0:arm64 (5.4.8-1) ... 440s Selecting previously unselected package libthai-data. 440s Preparing to unpack .../042-libthai-data_0.1.30-1_all.deb ... 440s Unpacking libthai-data (0.1.30-1) ... 440s Selecting previously unselected package libthai0:arm64. 440s Preparing to unpack .../043-libthai0_0.1.30-1_arm64.deb ... 440s Unpacking libthai0:arm64 (0.1.30-1) ... 440s Selecting previously unselected package libpango-1.0-0:arm64. 440s Preparing to unpack .../044-libpango-1.0-0_1.57.0-1_arm64.deb ... 440s Unpacking libpango-1.0-0:arm64 (1.57.0-1) ... 440s Selecting previously unselected package libpangoft2-1.0-0:arm64. 440s Preparing to unpack .../045-libpangoft2-1.0-0_1.57.0-1_arm64.deb ... 440s Unpacking libpangoft2-1.0-0:arm64 (1.57.0-1) ... 440s Selecting previously unselected package libpangocairo-1.0-0:arm64. 440s Preparing to unpack .../046-libpangocairo-1.0-0_1.57.0-1_arm64.deb ... 440s Unpacking libpangocairo-1.0-0:arm64 (1.57.0-1) ... 440s Selecting previously unselected package libpaper2:arm64. 440s Preparing to unpack .../047-libpaper2_2.2.5-0.3build1_arm64.deb ... 440s Unpacking libpaper2:arm64 (2.2.5-0.3build1) ... 440s Selecting previously unselected package libpaper-utils. 440s Preparing to unpack .../048-libpaper-utils_2.2.5-0.3build1_arm64.deb ... 440s Unpacking libpaper-utils (2.2.5-0.3build1) ... 440s Selecting previously unselected package libsharpyuv0:arm64. 440s Preparing to unpack .../049-libsharpyuv0_1.5.0-0.1build1_arm64.deb ... 440s Unpacking libsharpyuv0:arm64 (1.5.0-0.1build1) ... 440s Selecting previously unselected package libsm6:arm64. 440s Preparing to unpack .../050-libsm6_2%3a1.2.6-1build1_arm64.deb ... 440s Unpacking libsm6:arm64 (2:1.2.6-1build1) ... 440s Selecting previously unselected package libtcl8.6:arm64. 440s Preparing to unpack .../051-libtcl8.6_8.6.17+dfsg-1build1_arm64.deb ... 440s Unpacking libtcl8.6:arm64 (8.6.17+dfsg-1build1) ... 440s Selecting previously unselected package libjbig0:arm64. 440s Preparing to unpack .../052-libjbig0_2.1-6.1ubuntu3_arm64.deb ... 440s Unpacking libjbig0:arm64 (2.1-6.1ubuntu3) ... 440s Selecting previously unselected package libwebp7:arm64. 440s Preparing to unpack .../053-libwebp7_1.5.0-0.1build1_arm64.deb ... 440s Unpacking libwebp7:arm64 (1.5.0-0.1build1) ... 440s Selecting previously unselected package libtiff6:arm64. 440s Preparing to unpack .../054-libtiff6_4.7.0-3ubuntu3_arm64.deb ... 440s Unpacking libtiff6:arm64 (4.7.0-3ubuntu3) ... 440s Selecting previously unselected package libxft2:arm64. 440s Preparing to unpack .../055-libxft2_2.3.6-1build2_arm64.deb ... 440s Unpacking libxft2:arm64 (2.3.6-1build2) ... 440s Selecting previously unselected package libxss1:arm64. 440s Preparing to unpack .../056-libxss1_1%3a1.2.3-1build4_arm64.deb ... 440s Unpacking libxss1:arm64 (1:1.2.3-1build4) ... 440s Selecting previously unselected package libtk8.6:arm64. 441s Preparing to unpack .../057-libtk8.6_8.6.17-1_arm64.deb ... 441s Unpacking libtk8.6:arm64 (8.6.17-1) ... 441s Selecting previously unselected package libxt6t64:arm64. 441s Preparing to unpack .../058-libxt6t64_1%3a1.2.1-1.3_arm64.deb ... 441s Unpacking libxt6t64:arm64 (1:1.2.1-1.3) ... 441s Selecting previously unselected package node-bootstrap-sass. 441s Preparing to unpack .../059-node-bootstrap-sass_3.4.3-2_all.deb ... 441s Unpacking node-bootstrap-sass (3.4.3-2) ... 441s Selecting previously unselected package node-html5shiv. 441s Preparing to unpack .../060-node-html5shiv_3.7.3+dfsg-5_all.deb ... 441s Unpacking node-html5shiv (3.7.3+dfsg-5) ... 441s Selecting previously unselected package node-normalize.css. 441s Preparing to unpack .../061-node-normalize.css_8.0.1-5.1_all.deb ... 441s Unpacking node-normalize.css (8.0.1-5.1) ... 441s Selecting previously unselected package pandoc-data. 441s Preparing to unpack .../062-pandoc-data_3.1.11.1-3build1_all.deb ... 441s Unpacking pandoc-data (3.1.11.1-3build1) ... 441s Selecting previously unselected package pandoc. 441s Preparing to unpack .../063-pandoc_3.1.11.1+ds-4_arm64.deb ... 441s Unpacking pandoc (3.1.11.1+ds-4) ... 442s Selecting previously unselected package zip. 442s Preparing to unpack .../064-zip_3.0-15ubuntu3_arm64.deb ... 442s Unpacking zip (3.0-15ubuntu3) ... 442s Selecting previously unselected package unzip. 442s Preparing to unpack .../065-unzip_6.0-29ubuntu1_arm64.deb ... 442s Unpacking unzip (6.0-29ubuntu1) ... 442s Selecting previously unselected package xdg-utils. 442s Preparing to unpack .../066-xdg-utils_1.2.1-2ubuntu2_all.deb ... 442s Unpacking xdg-utils (1.2.1-2ubuntu2) ... 442s Selecting previously unselected package r-base-core. 442s Preparing to unpack .../067-r-base-core_4.5.2-1ubuntu2_arm64.deb ... 442s Unpacking r-base-core (4.5.2-1ubuntu2) ... 442s Selecting previously unselected package r-cran-base64enc. 442s Preparing to unpack .../068-r-cran-base64enc_0.1-3-3build1_arm64.deb ... 442s Unpacking r-cran-base64enc (0.1-3-3build1) ... 442s Selecting previously unselected package r-cran-brio. 442s Preparing to unpack .../069-r-cran-brio_1.1.5-1_arm64.deb ... 442s Unpacking r-cran-brio (1.1.5-1) ... 442s Selecting previously unselected package r-cran-rlang. 442s Preparing to unpack .../070-r-cran-rlang_1.1.5-3_arm64.deb ... 442s Unpacking r-cran-rlang (1.1.5-3) ... 442s Selecting previously unselected package r-cran-fastmap. 442s Preparing to unpack .../071-r-cran-fastmap_1.2.0-1_arm64.deb ... 442s Unpacking r-cran-fastmap (1.2.0-1) ... 442s Selecting previously unselected package r-cran-cachem. 442s Preparing to unpack .../072-r-cran-cachem_1.1.0-1_arm64.deb ... 442s Unpacking r-cran-cachem (1.1.0-1) ... 442s Selecting previously unselected package r-cran-digest. 442s Preparing to unpack .../073-r-cran-digest_0.6.39-1_arm64.deb ... 442s Unpacking r-cran-digest (0.6.39-1) ... 442s Selecting previously unselected package r-cran-htmltools. 442s Preparing to unpack .../074-r-cran-htmltools_0.5.8.1-1_arm64.deb ... 442s Unpacking r-cran-htmltools (0.5.8.1-1) ... 442s Selecting previously unselected package r-cran-jquerylib. 442s Preparing to unpack .../075-r-cran-jquerylib_0.1.4+dfsg-5_all.deb ... 442s Unpacking r-cran-jquerylib (0.1.4+dfsg-5) ... 442s Selecting previously unselected package r-cran-jsonlite. 442s Preparing to unpack .../076-r-cran-jsonlite_1.9.1+dfsg-1_arm64.deb ... 442s Unpacking r-cran-jsonlite (1.9.1+dfsg-1) ... 442s Selecting previously unselected package r-cran-cli. 442s Preparing to unpack .../077-r-cran-cli_3.6.4-1_arm64.deb ... 442s Unpacking r-cran-cli (3.6.4-1) ... 442s Selecting previously unselected package r-cran-lifecycle. 442s Preparing to unpack .../078-r-cran-lifecycle_1.0.5+dfsg-1_all.deb ... 442s Unpacking r-cran-lifecycle (1.0.5+dfsg-1) ... 443s Selecting previously unselected package r-cran-memoise. 443s Preparing to unpack .../079-r-cran-memoise_2.0.1-1build1_all.deb ... 443s Unpacking r-cran-memoise (2.0.1-1build1) ... 443s Selecting previously unselected package r-cran-mime. 443s Preparing to unpack .../080-r-cran-mime_0.12-2_arm64.deb ... 443s Unpacking r-cran-mime (0.12-2) ... 443s Selecting previously unselected package r-cran-fs. 443s Preparing to unpack .../081-r-cran-fs_1.6.5+dfsg-1_arm64.deb ... 443s Unpacking r-cran-fs (1.6.5+dfsg-1) ... 443s Selecting previously unselected package r-cran-r6. 443s Preparing to unpack .../082-r-cran-r6_2.6.1-1_all.deb ... 443s Unpacking r-cran-r6 (2.6.1-1) ... 443s Selecting previously unselected package r-cran-rappdirs. 443s Preparing to unpack .../083-r-cran-rappdirs_0.3.3-1build1_arm64.deb ... 443s Unpacking r-cran-rappdirs (0.3.3-1build1) ... 443s Selecting previously unselected package r-cran-sass. 443s Preparing to unpack .../084-r-cran-sass_0.4.9+dfsg-1_arm64.deb ... 443s Unpacking r-cran-sass (0.4.9+dfsg-1) ... 443s Selecting previously unselected package r-cran-bslib. 443s Preparing to unpack .../085-r-cran-bslib_0.9.0+dfsg-3build1_all.deb ... 443s Unpacking r-cran-bslib (0.9.0+dfsg-3build1) ... 443s Selecting previously unselected package r-cran-ps. 443s Preparing to unpack .../086-r-cran-ps_1.9.0-1_arm64.deb ... 443s Unpacking r-cran-ps (1.9.0-1) ... 443s Selecting previously unselected package r-cran-processx. 443s Preparing to unpack .../087-r-cran-processx_3.8.6-1_arm64.deb ... 443s Unpacking r-cran-processx (3.8.6-1) ... 443s Selecting previously unselected package r-cran-callr. 443s Preparing to unpack .../088-r-cran-callr_3.7.6-1_all.deb ... 443s Unpacking r-cran-callr (3.7.6-1) ... 443s Selecting previously unselected package r-cran-codetools. 443s Preparing to unpack .../089-r-cran-codetools_0.2-20-1build1_all.deb ... 443s Unpacking r-cran-codetools (0.2-20-1build1) ... 443s Selecting previously unselected package r-cran-commonmark. 443s Preparing to unpack .../090-r-cran-commonmark_1.9.5-1_arm64.deb ... 443s Unpacking r-cran-commonmark (1.9.5-1) ... 443s Selecting previously unselected package r-cran-crayon. 443s Preparing to unpack .../091-r-cran-crayon_1.5.3-1_all.deb ... 443s Unpacking r-cran-crayon (1.5.3-1) ... 443s Selecting previously unselected package r-cran-desc. 443s Preparing to unpack .../092-r-cran-desc_1.4.3-1_all.deb ... 443s Unpacking r-cran-desc (1.4.3-1) ... 443s Selecting previously unselected package r-cran-diffobj. 443s Preparing to unpack .../093-r-cran-diffobj_0.3.5-1build1_arm64.deb ... 443s Unpacking r-cran-diffobj (0.3.5-1build1) ... 443s Selecting previously unselected package r-cran-glue. 443s Preparing to unpack .../094-r-cran-glue_1.8.0-1_arm64.deb ... 443s Unpacking r-cran-glue (1.8.0-1) ... 443s Selecting previously unselected package r-cran-gtable. 443s Preparing to unpack .../095-r-cran-gtable_0.3.6+dfsg-1_all.deb ... 443s Unpacking r-cran-gtable (0.3.6+dfsg-1) ... 443s Selecting previously unselected package r-cran-isoband. 443s Preparing to unpack .../096-r-cran-isoband_0.2.7-1_arm64.deb ... 443s Unpacking r-cran-isoband (0.2.7-1) ... 443s Selecting previously unselected package r-cran-mass. 443s Preparing to unpack .../097-r-cran-mass_7.3-65-1_arm64.deb ... 443s Unpacking r-cran-mass (7.3-65-1) ... 444s Selecting previously unselected package r-cran-lattice. 444s Preparing to unpack .../098-r-cran-lattice_0.22-9-1_arm64.deb ... 444s Unpacking r-cran-lattice (0.22-9-1) ... 444s Selecting previously unselected package r-cran-nlme. 444s Preparing to unpack .../099-r-cran-nlme_3.1.168-1_arm64.deb ... 444s Unpacking r-cran-nlme (3.1.168-1) ... 444s Selecting previously unselected package r-cran-matrix. 444s Preparing to unpack .../100-r-cran-matrix_1.7-4-1_arm64.deb ... 444s Unpacking r-cran-matrix (1.7-4-1) ... 444s Selecting previously unselected package r-cran-mgcv. 444s Preparing to unpack .../101-r-cran-mgcv_1.9-4-1_arm64.deb ... 444s Unpacking r-cran-mgcv (1.9-4-1) ... 444s Selecting previously unselected package r-cran-farver. 444s Preparing to unpack .../102-r-cran-farver_2.1.2-1_arm64.deb ... 444s Unpacking r-cran-farver (2.1.2-1) ... 444s Selecting previously unselected package r-cran-labeling. 444s Preparing to unpack .../103-r-cran-labeling_0.4.3-1_all.deb ... 444s Unpacking r-cran-labeling (0.4.3-1) ... 444s Selecting previously unselected package r-cran-rcolorbrewer. 444s Preparing to unpack .../104-r-cran-rcolorbrewer_1.1-3-1build2_all.deb ... 444s Unpacking r-cran-rcolorbrewer (1.1-3-1build2) ... 444s Selecting previously unselected package r-cran-viridislite. 444s Preparing to unpack .../105-r-cran-viridislite_0.4.3-1_all.deb ... 444s Unpacking r-cran-viridislite (0.4.3-1) ... 444s Selecting previously unselected package r-cran-scales. 444s Preparing to unpack .../106-r-cran-scales_1.4.0-1_all.deb ... 444s Unpacking r-cran-scales (1.4.0-1) ... 444s Selecting previously unselected package r-cran-fansi. 444s Preparing to unpack .../107-r-cran-fansi_1.0.6-2_arm64.deb ... 444s Unpacking r-cran-fansi (1.0.6-2) ... 444s Selecting previously unselected package r-cran-magrittr. 444s Preparing to unpack .../108-r-cran-magrittr_2.0.3-1_arm64.deb ... 444s Unpacking r-cran-magrittr (2.0.3-1) ... 444s Selecting previously unselected package r-cran-utf8. 444s Preparing to unpack .../109-r-cran-utf8_1.2.4-1_arm64.deb ... 444s Unpacking r-cran-utf8 (1.2.4-1) ... 444s Selecting previously unselected package r-cran-vctrs. 444s Preparing to unpack .../110-r-cran-vctrs_0.6.5-1_arm64.deb ... 444s Unpacking r-cran-vctrs (0.6.5-1) ... 444s Selecting previously unselected package r-cran-pillar. 444s Preparing to unpack .../111-r-cran-pillar_1.11.1+dfsg-1_all.deb ... 444s Unpacking r-cran-pillar (1.11.1+dfsg-1) ... 444s Selecting previously unselected package r-cran-pkgconfig. 444s Preparing to unpack .../112-r-cran-pkgconfig_2.0.3-2build2_all.deb ... 444s Unpacking r-cran-pkgconfig (2.0.3-2build2) ... 444s Selecting previously unselected package r-cran-tibble. 444s Preparing to unpack .../113-r-cran-tibble_3.2.1+dfsg-3_arm64.deb ... 444s Unpacking r-cran-tibble (3.2.1+dfsg-3) ... 444s Selecting previously unselected package r-cran-withr. 444s Preparing to unpack .../114-r-cran-withr_3.0.2+dfsg-1_all.deb ... 444s Unpacking r-cran-withr (3.0.2+dfsg-1) ... 444s Selecting previously unselected package r-cran-ggplot2. 444s Preparing to unpack .../115-r-cran-ggplot2_3.5.1+dfsg-1_all.deb ... 444s Unpacking r-cran-ggplot2 (3.5.1+dfsg-1) ... 445s Selecting previously unselected package r-cran-mvtnorm. 445s Preparing to unpack .../116-r-cran-mvtnorm_1.3-3-1build1_arm64.deb ... 445s Unpacking r-cran-mvtnorm (1.3-3-1build1) ... 445s Selecting previously unselected package r-cran-dosefinding. 445s Preparing to unpack .../117-r-cran-dosefinding_1.3-1-1_arm64.deb ... 445s Unpacking r-cran-dosefinding (1.3-1-1) ... 445s Selecting previously unselected package r-cran-evaluate. 445s Preparing to unpack .../118-r-cran-evaluate_1.0.5-1_all.deb ... 445s Unpacking r-cran-evaluate (1.0.5-1) ... 445s Selecting previously unselected package r-cran-fontawesome. 445s Preparing to unpack .../119-r-cran-fontawesome_0.5.3-1_all.deb ... 445s Unpacking r-cran-fontawesome (0.5.3-1) ... 445s Selecting previously unselected package r-cran-xfun. 445s Preparing to unpack .../120-r-cran-xfun_0.55+dfsg-1_arm64.deb ... 445s Unpacking r-cran-xfun (0.55+dfsg-1) ... 445s Selecting previously unselected package r-cran-highr. 445s Preparing to unpack .../121-r-cran-highr_0.11+dfsg-1_all.deb ... 445s Unpacking r-cran-highr (0.11+dfsg-1) ... 445s Selecting previously unselected package r-cran-littler. 445s Preparing to unpack .../122-r-cran-littler_0.3.22-1_arm64.deb ... 445s Unpacking r-cran-littler (0.3.22-1) ... 445s Selecting previously unselected package r-cran-pkgkitten. 445s Preparing to unpack .../123-r-cran-pkgkitten_0.2.4-1_all.deb ... 445s Unpacking r-cran-pkgkitten (0.2.4-1) ... 445s Selecting previously unselected package r-cran-rcpp. 445s Preparing to unpack .../124-r-cran-rcpp_1.1.0-1_arm64.deb ... 445s Unpacking r-cran-rcpp (1.1.0-1) ... 445s Selecting previously unselected package r-cran-later. 445s Preparing to unpack .../125-r-cran-later_1.4.1+dfsg-1_arm64.deb ... 445s Unpacking r-cran-later (1.4.1+dfsg-1) ... 445s Selecting previously unselected package r-cran-promises. 445s Preparing to unpack .../126-r-cran-promises_1.3.2+dfsg-1_arm64.deb ... 445s Unpacking r-cran-promises (1.3.2+dfsg-1) ... 445s Selecting previously unselected package r-cran-httpuv. 445s Preparing to unpack .../127-r-cran-httpuv_1.6.15+dfsg-1_arm64.deb ... 445s Unpacking r-cran-httpuv (1.6.15+dfsg-1) ... 445s Selecting previously unselected package r-cran-yaml. 445s Preparing to unpack .../128-r-cran-yaml_2.3.10-1_arm64.deb ... 445s Unpacking r-cran-yaml (2.3.10-1) ... 445s Selecting previously unselected package libjs-mathjax. 445s Preparing to unpack .../129-libjs-mathjax_2.7.9+dfsg-1build1_all.deb ... 445s Unpacking libjs-mathjax (2.7.9+dfsg-1build1) ... 446s Selecting previously unselected package r-cran-knitr. 446s Preparing to unpack .../130-r-cran-knitr_1.51+dfsg-1_all.deb ... 446s Unpacking r-cran-knitr (1.51+dfsg-1) ... 446s Selecting previously unselected package r-cran-survival. 446s Preparing to unpack .../131-r-cran-survival_3.8-6-1_arm64.deb ... 446s Unpacking r-cran-survival (3.8-6-1) ... 446s Selecting previously unselected package r-cran-th.data. 446s Preparing to unpack .../132-r-cran-th.data_1.1-5-1_all.deb ... 446s Unpacking r-cran-th.data (1.1-5-1) ... 446s Selecting previously unselected package r-cran-zoo. 446s Preparing to unpack .../133-r-cran-zoo_1.8-15-1_arm64.deb ... 446s Unpacking r-cran-zoo (1.8-15-1) ... 446s Selecting previously unselected package r-cran-sandwich. 446s Preparing to unpack .../134-r-cran-sandwich_3.1-1-1build1_all.deb ... 446s Unpacking r-cran-sandwich (3.1-1-1build1) ... 446s Selecting previously unselected package r-cran-multcomp. 446s Preparing to unpack .../135-r-cran-multcomp_1.4-29-1_all.deb ... 446s Unpacking r-cran-multcomp (1.4-29-1) ... 446s Selecting previously unselected package r-cran-numderiv. 446s Preparing to unpack .../136-r-cran-numderiv_2016.8-1.1-3build1_all.deb ... 446s Unpacking r-cran-numderiv (2016.8-1.1-3build1) ... 446s Selecting previously unselected package r-cran-pkgbuild. 446s Preparing to unpack .../137-r-cran-pkgbuild_1.4.8-1_all.deb ... 446s Unpacking r-cran-pkgbuild (1.4.8-1) ... 446s Selecting previously unselected package r-cran-rprojroot. 446s Preparing to unpack .../138-r-cran-rprojroot_2.1.1-1_all.deb ... 446s Unpacking r-cran-rprojroot (2.1.1-1) ... 446s Selecting previously unselected package r-cran-pkgload. 446s Preparing to unpack .../139-r-cran-pkgload_1.4.1-1_all.deb ... 446s Unpacking r-cran-pkgload (1.4.1-1) ... 446s Selecting previously unselected package r-cran-praise. 446s Preparing to unpack .../140-r-cran-praise_1.0.0-4build2_all.deb ... 446s Unpacking r-cran-praise (1.0.0-4build2) ... 446s Selecting previously unselected package r-cran-quadprog. 446s Preparing to unpack .../141-r-cran-quadprog_1.5-8-1build2_arm64.deb ... 446s Unpacking r-cran-quadprog (1.5-8-1build2) ... 446s Selecting previously unselected package r-cran-tinytex. 446s Preparing to unpack .../142-r-cran-tinytex_0.58-1_all.deb ... 446s Unpacking r-cran-tinytex (0.58-1) ... 446s Selecting previously unselected package libjs-modernizr. 446s Preparing to unpack .../143-libjs-modernizr_3.13.0-0.1build1_all.deb ... 446s Unpacking libjs-modernizr (3.13.0-0.1build1) ... 446s Selecting previously unselected package r-cran-xtable. 446s Preparing to unpack .../144-r-cran-xtable_1%3a1.8-4-2build1_all.deb ... 446s Unpacking r-cran-xtable (1:1.8-4-2build1) ... 446s Selecting previously unselected package r-cran-sourcetools. 446s Preparing to unpack .../145-r-cran-sourcetools_0.1.7-1-1_arm64.deb ... 446s Unpacking r-cran-sourcetools (0.1.7-1-1) ... 447s Selecting previously unselected package libjs-twitter-bootstrap-datepicker. 447s Preparing to unpack .../146-libjs-twitter-bootstrap-datepicker_1.3.1+dfsg1-4.1_all.deb ... 447s Unpacking libjs-twitter-bootstrap-datepicker (1.3.1+dfsg1-4.1) ... 447s Selecting previously unselected package r-cran-shiny. 447s Preparing to unpack .../147-r-cran-shiny_1.10.0+dfsg-2_all.deb ... 447s Unpacking r-cran-shiny (1.10.0+dfsg-2) ... 447s Selecting previously unselected package r-cran-rmarkdown. 447s Preparing to unpack .../148-r-cran-rmarkdown_2.30+dfsg-1_all.deb ... 447s Unpacking r-cran-rmarkdown (2.30+dfsg-1) ... 447s Selecting previously unselected package r-cran-truncnorm. 447s Preparing to unpack .../149-r-cran-truncnorm_1.0-9-2_arm64.deb ... 447s Unpacking r-cran-truncnorm (1.0-9-2) ... 447s Selecting previously unselected package r-cran-rsolnp. 447s Preparing to unpack .../150-r-cran-rsolnp_1.16+dfsg-4build2_all.deb ... 447s Unpacking r-cran-rsolnp (1.16+dfsg-4build2) ... 447s Selecting previously unselected package r-cran-waldo. 447s Preparing to unpack .../151-r-cran-waldo_0.6.2-1_all.deb ... 447s Unpacking r-cran-waldo (0.6.2-1) ... 447s Selecting previously unselected package r-cran-testthat. 447s Preparing to unpack .../152-r-cran-testthat_3.2.3-1_arm64.deb ... 447s Unpacking r-cran-testthat (3.2.3-1) ... 447s Setting up libjs-json (0~20221030+~1.0.8-1build1) ... 447s Setting up javascript-common (12+nmu1build1) ... 447s Setting up libgraphite2-3:arm64 (1.3.14-11ubuntu1) ... 447s Setting up libpixman-1-0:arm64 (0.46.4-1) ... 447s Setting up libsharpyuv0:arm64 (1.5.0-0.1build1) ... 447s 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(3.7.6-1) ... 450s Setting up r-cran-desc (1.4.3-1) ... 450s Setting up r-cran-tibble (3.2.1+dfsg-3) ... 450s Setting up r-cran-sandwich (3.1-1-1build1) ... 450s Setting up r-cran-fontawesome (0.5.3-1) ... 450s Setting up r-cran-survival (3.8-6-1) ... 450s Setting up r-cran-jquerylib (0.1.4+dfsg-5) ... 450s Setting up r-cran-th.data (1.1-5-1) ... 450s Setting up r-cran-memoise (2.0.1-1build1) ... 450s Setting up r-cran-promises (1.3.2+dfsg-1) ... 450s Setting up r-cran-multcomp (1.4-29-1) ... 450s Setting up r-cran-pkgbuild (1.4.8-1) ... 450s Setting up r-cran-pkgload (1.4.1-1) ... 450s Setting up r-cran-ggplot2 (3.5.1+dfsg-1) ... 450s Setting up r-cran-httpuv (1.6.15+dfsg-1) ... 450s Setting up r-cran-testthat (3.2.3-1) ... 450s Setting up r-cran-bslib (0.9.0+dfsg-3build1) ... 450s Setting up r-cran-dosefinding (1.3-1-1) ... 450s Setting up r-cran-shiny (1.10.0+dfsg-2) ... 450s Setting up r-cran-rmarkdown (2.30+dfsg-1) ... 450s Processing triggers for libc-bin (2.42-2ubuntu4) ... 450s Processing triggers for man-db (2.13.1-1build1) ... 451s Processing triggers for install-info (7.2-5) ... 452s autopkgtest [23:46:49]: test run-unit-test: [----------------------- 452s Loading required package: DoseFinding 453s Dose Response Model 453s 453s Model: linear 453s Fit-type: general 453s 453s Coefficients dose-response model 453s delta 453s 0.07484 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 3.472 453s Dose Response Model 453s 453s Model: linear 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 delta 453s 0.33400 0.07484 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 3.472 453s Dose Response Model 453s 453s Model: quadratic 453s Fit-type: general 453s 453s Coefficients dose-response model 453s b1 b2 453s 0.22800 -0.03811 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.9281 453s Dose Response Model 453s 453s Model: quadratic 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 b1 b2 453s 0.24950 0.22800 -0.03811 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.9281 453s Dose Response Model 453s 453s Model: linlog 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 delta 453s 0.47790 0.07728 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.1605 453s Dose Response Model 453s 453s Model: emax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s eMax ed50 453s 0.3771 0.3630 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.09815 453s Dose Response Model 453s 453s Model: emax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax ed50 453s 0.2221 0.3771 0.3630 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.09815 453s Dose Response Model 453s 453s Model: sigEmax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s eMax ed50 h 453s 0.4714 0.4880 0.5000 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.07825 453s Dose Response Model 453s 453s Model: sigEmax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax ed50 h 453s 0.2223 0.4714 0.4880 0.5000 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.07825 453s Dose Response Model 453s 453s Model: exponential 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e1 delta 453s 0.4391 8.0000 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 4.102 453s Dose Response Model 453s 453s Model: exponential 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 e1 delta 453s 0.3510 0.4391 8.0000 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 4.102 453s Dose Response Model 453s 453s Model: logistic 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax ed50 delta 453s -0.1095 0.6665 0.0040 0.4217 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.1951 453s Dose Response Model 453s 453s Model: betaMod 453s Fit-type: general 453s 453s Coefficients dose-response model 453s eMax delta1 delta2 453s 0.3468 0.2216 0.0500 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.0783 453s Dose Response Model 453s 453s Model: betaMod 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax delta1 delta2 453s 0.2222 0.3468 0.2216 0.0500 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.0783 453s Dose Response Model 453s 453s Model: linInt 453s Fit-type: general 453s 453s Coefficients dose-response model 453s d1 d2 d3 d4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0 453s Dose Response Model 453s 453s Model: linInt 453s Fit-type: general 453s 453s Coefficients dose-response model 453s d0 d1 d2 d3 d4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0 453s Dose Response Model 453s 453s Model: emax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s eMax ed50 453s 0.3771 0.3630 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.09815 453s Dose Response Model 453s 453s Model: emax 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax ed50 453s 0.2221 0.3771 0.3630 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.09815 453s Dose Response Model 453s 453s Model: betaMod 453s Fit-type: general 453s 453s Coefficients dose-response model 453s eMax delta1 delta2 453s 0.3468 0.2216 0.0500 453s 453s Fitted to: 453s 1 2 3 4 453s 0.2846 0.2965 0.3502 0.3480 453s 453s Generalized residual sum of squares: 0.0783 453s Dose Response Model 453s 453s Model: betaMod 453s Fit-type: general 453s 453s Coefficients dose-response model 453s e0 eMax delta1 delta2 453s 0.2222 0.3468 0.2216 0.0500 453s 453s Fitted to: 453s 0 1 2 3 4 453s 0.2220 0.5065 0.5185 0.5722 0.5700 453s 453s Generalized residual sum of squares: 0.0783 453s $fit 453s [1] 0.0000000 0.2756421 0.3165257 0.3387105 0.3466573 453s 453s $se.fit 453s [1] 0.0000000 0.1235753 0.1106156 0.1135736 0.1263900 453s 453s $fit 453s [1] 0.2756421 0.3165257 0.3387105 0.3466573 453s 453s $se.fit 453s [1] 0.1235753 0.1106156 0.1135736 0.1263900 453s 453s e0 eMax delta1 delta2 453s e0 0.0118410628 -0.008186899 0.003722514 -0.0008419768 453s eMax -0.0081868987 0.014334651 -0.016984399 -0.0239850493 453s delta1 0.0037225142 -0.016984399 0.475384246 0.3641344057 453s delta2 -0.0008419768 -0.023985049 0.364134406 0.3356088149 453s eMax delta1 delta2 453s eMax 0.01433465 -0.0169844 -0.02398505 453s delta1 -0.01698440 0.4753842 0.36413441 453s delta2 -0.02398505 0.3641344 0.33560881 453s Message: Setting predType to "ls-means" for "type = general" 453s $fit 453s [1] 0.2219856 0.5065390 0.5185323 0.5721580 0.5699850 453s 453s $se.fit 453s [1] 0.1088272 0.1048057 0.1044027 0.1046862 0.1088405 453s 453s $fit 453s [1] 0.0000000 0.2845534 0.2965467 0.3501724 0.3479994 453s 453s $se.fit 453s [1] 0.0000000 0.1252903 0.1265494 0.1279290 0.1273279 453s 453s Message: Setting predType to "effect-curve" for placebo-adjusted data 453s $fit 453s [1] 0.2845534 0.2965467 0.3501724 0.3479994 453s 453s $se.fit 453s [1] 0.1252903 0.1265494 0.1279290 0.1273279 453s 453s d0 d1 d2 d3 d4 453s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 453s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 453s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 453s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 453s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 453s d1 d2 d3 d4 453s d1 0.015697662 0.008221459 0.008223928 0.008215124 453s d2 0.008221459 0.016014746 0.008246506 0.008208911 453s d3 0.008223928 0.008246506 0.016365819 0.008204394 453s d4 0.008215124 0.008208911 0.008204394 0.016212400 453s d0 d1 d2 d3 d4 453s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 453s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 453s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 453s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 453s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 453s gender2 -0.005149393 -0.005062250 -0.004777264 -0.004570087 -0.005308813 453s gender2 453s d0 -0.005149393 453s d1 -0.005062250 453s d2 -0.004777264 453s d3 -0.004570087 453s d4 -0.005308813 453s gender2 0.007312139 453s d0 d1 d2 d3 d4 453s d0 0.00819461 0.000000000 0.000000000 0.000000000 0.0000000 453s d1 0.00000000 0.007459197 0.000000000 0.000000000 0.0000000 453s d2 0.00000000 0.000000000 0.007757564 0.000000000 0.0000000 453s d3 0.00000000 0.000000000 0.000000000 0.008080796 0.0000000 453s d4 0.00000000 0.000000000 0.000000000 0.000000000 0.0079701 453s d1 d2 d3 d4 453s d1 0.015697662 0.008221459 0.008223928 0.008215124 453s d2 0.008221459 0.016014746 0.008246506 0.008208911 453s d3 0.008223928 0.008246506 0.016365819 0.008204394 453s d4 0.008215124 0.008208911 0.008204394 0.016212400 453s $fit 453s [1] 0.2845534 0.2965467 0.3501724 0.3479994 453s 453s $se.fit 453s [1] 0.1252903 0.1265494 0.1279290 0.1273279 453s 453s testgFit.R passed 454s testplanMod.R passed 454s Loading required package: DoseFinding 454s [1] 0.5099184 454s Calculated TD - optimal design: 454s 0 18.75 454s 0.49999 0.50001 454s Calculated TD - optimal design: 454s 0 104.52 454s 0.49993 0.50006 454s [1] 0.4286171 454s Calculated TD - optimal design: 454s 0 101.57 150 454s 0.43958 0.50000 0.06041 454s Calculated TD - optimal design: 454s 0 37.29 64.44 150 454s 0.40070 0.45303 0.09933 0.04694 454s [1] 0.1853293 454s Calculated TD - optimal design: 454s 0 50.22 454s 0.5 0.5 454s Calculated TD - optimal design: 454s 0 0.49 25.2 108.07 454s 0.44787 0.47652 0.05213 0.02348 454s [1] 0.130092 454s Calculated TD - optimal design: 454s 0 27 94.89 150 454s 0.44879 0.47519 0.05121 0.02481 454s [1] 0.5013672 454s Calculated TD - optimal design: 454s 0 0.35 150 454s 0.49865 0.50000 0.00135 454s [1] 0.05572985 455s [1] 4.478701e-01 4.765233e-01 5.212994e-02 2.347673e-02 6.509030e-09 455s [1] 4.478701e-01 4.765233e-01 5.212991e-02 2.347669e-02 5.680431e-09 455s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 455s [1,] 0.246 0.142 0.122 0.000 0.000 0.241 0 0 0.249 455s [2,] 0.248 0.234 0.059 0.211 0.000 0.000 0 0 0.248 455s [3,] 0.247 0.000 0.000 0.224 0.081 0.203 0 0 0.246 455s [4,] 0.250 0.248 0.044 0.210 0.000 0.000 0 0 0.249 455s [5,] 0.250 0.248 0.191 0.064 0.000 0.000 0 0 0.247 455s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 455s [1,] 0.49 0.01 0.00 0.00 0.00 0.00 0.36 0.14 0.00 455s [2,] 0.48 0.02 0.00 0.32 0.18 0.00 0.00 0.00 0.00 455s [3,] 0.21 0.29 0.00 0.00 0.00 0.46 0.04 0.00 0.00 455s [4,] 0.50 0.00 0.49 0.01 0.00 0.00 0.00 0.00 0.00 455s [5,] 0.49 0.02 0.48 0.00 0.00 0.00 0.00 0.00 0.01 455s [1] 0.8823949 455s Calculated D - optimal design: 455s 0 1 455s 0.5 0.5 456s Calculated TD - optimal design: 456s 0 0.25 0.5 1 456s 0.48951 0.35517 0.14483 0.01049 456s testsDesign.R passed 456s Loading required package: DoseFinding 456s [1] 3714.641 456s [1] 3714.641 456s Dose Response Model 456s 456s Model: betaMod 456s Fit-type: normal 456s 456s Residuals: 456s Min 1Q Median 3Q Max 456s -23.368 -3.727 0.129 3.894 16.152 456s 456s Coefficients with approx. stand. error: 456s Estimate Std. Error 456s e0 10.80 0.565 456s eMax 7.41 0.692 456s delta1 2.24 0.589 456s delta2 1.00 0.328 456s 456s Residual standard error: 5.64 456s Degrees of freedom: 585 456s 456s Formula: y ~ betaMod(x, e0, emax, delta1, delta2, 1.2 * max(datset$x)) 456s 456s Parameters: 456s Estimate Std. Error t value Pr(>|t|) 456s e0 10.7964 0.5653 19.098 < 2e-16 *** 456s emax 7.4106 0.6917 10.714 < 2e-16 *** 456s delta1 2.2357 0.5885 3.799 0.000161 *** 456s delta2 1.0047 0.3277 3.066 0.002271 ** 456s --- 456s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 456s 456s Residual standard error: 5.637 on 585 degrees of freedom 456s 456s Number of iterations to convergence: 6 456s Achieved convergence tolerance: 4.025e-06 456s 456s e0 eMax delta1 delta2 456s e0 0.31958673 -0.28252697 0.20809234 0.09247897 456s eMax -0.28252697 0.47843297 -0.04177476 0.01244179 456s delta1 0.20809234 -0.04177476 0.34639417 0.18051781 456s delta2 0.09247897 0.01244179 0.18051781 0.10741016 456s e0 emax delta1 delta2 456s e0 0.31959067 -0.28253043 0.2080897 0.09247786 456s emax -0.28253043 0.47843379 -0.0417750 0.01244127 456s delta1 0.20808969 -0.04177500 0.3463820 0.18051234 456s delta2 0.09247786 0.01244127 0.1805123 0.10740755 456s $fit 456s [1] 6.0578751 6.8058158 7.2227652 6.0578751 3.1444084 6.8058158 7.2227652 456s [8] 3.1444084 6.0578751 0.0000000 6.0578751 6.0578751 7.2227652 3.1444084 456s [15] 0.8440180 0.0000000 6.0578751 3.1444084 3.1444084 0.0000000 7.2227652 456s [22] 0.0000000 7.2227652 6.8058158 6.8058158 3.1444084 6.8058158 6.8058158 456s [29] 3.1444084 6.0578751 7.2227652 6.8058158 3.1444084 3.1444084 3.1444084 456s [36] 0.0000000 0.0000000 3.1444084 6.8058158 3.1444084 3.1444084 0.8440180 456s [43] 3.1444084 6.0578751 3.1444084 6.0578751 0.8440180 7.2227652 0.8440180 456s [50] 0.8440180 0.0000000 7.2227652 6.8058158 6.8058158 7.2227652 3.1444084 456s [57] 7.2227652 6.8058158 0.8440180 0.8440180 3.1444084 0.0000000 7.2227652 456s [64] 6.8058158 6.8058158 6.8058158 0.0000000 7.2227652 3.1444084 6.0578751 456s [71] 0.0000000 0.8440180 0.8440180 6.8058158 3.1444084 3.1444084 6.0578751 456s [78] 0.0000000 6.0578751 6.8058158 6.8058158 3.1444084 3.1444084 3.1444084 456s [85] 3.1444084 7.2227652 6.8058158 0.8440180 0.0000000 0.8440180 7.2227652 456s [92] 6.8058158 3.1444084 7.2227652 6.0578751 6.8058158 6.0578751 6.8058158 456s [99] 6.8058158 6.8058158 3.1444084 6.0578751 6.8058158 0.0000000 6.0578751 456s [106] 6.8058158 0.0000000 6.8058158 3.1444084 3.1444084 0.8440180 6.8058158 456s [113] 6.0578751 3.1444084 0.1731496 6.0578751 6.0578751 0.0000000 6.8058158 456s [120] 0.0000000 0.0000000 6.8058158 0.1731496 0.8440180 0.0000000 6.0578751 456s [127] 6.8058158 3.1444084 6.0578751 0.8440180 6.8058158 0.8440180 7.2227652 456s [134] 6.8058158 3.1444084 6.0578751 6.8058158 7.2227652 6.8058158 0.1731496 456s [141] 6.8058158 6.8058158 0.8440180 6.8058158 6.0578751 7.2227652 6.8058158 456s [148] 3.1444084 3.1444084 0.0000000 6.0578751 3.1444084 0.0000000 3.1444084 456s [155] 6.8058158 7.2227652 6.8058158 0.0000000 0.0000000 0.8440180 3.1444084 456s [162] 0.0000000 0.1731496 3.1444084 3.1444084 6.0578751 0.0000000 0.8440180 456s [169] 0.0000000 3.1444084 3.1444084 6.0578751 6.0578751 0.0000000 7.2227652 456s [176] 0.8440180 0.0000000 6.0578751 0.0000000 7.2227652 0.0000000 3.1444084 456s [183] 6.0578751 6.0578751 3.1444084 3.1444084 0.1731496 7.2227652 3.1444084 456s [190] 0.8440180 7.2227652 7.2227652 0.8440180 0.0000000 7.2227652 3.1444084 456s [197] 7.2227652 7.2227652 0.1731496 3.1444084 0.0000000 7.2227652 3.1444084 456s [204] 6.8058158 6.8058158 7.2227652 6.8058158 7.2227652 0.8440180 6.0578751 456s [211] 3.1444084 3.1444084 3.1444084 0.0000000 0.0000000 6.0578751 6.0578751 456s [218] 3.1444084 3.1444084 0.1731496 7.2227652 7.2227652 0.0000000 0.8440180 456s [225] 7.2227652 0.8440180 3.1444084 0.8440180 0.0000000 7.2227652 3.1444084 456s [232] 6.8058158 6.8058158 3.1444084 0.8440180 6.0578751 0.8440180 0.0000000 456s [239] 0.0000000 6.8058158 7.2227652 6.8058158 6.0578751 3.1444084 7.2227652 456s [246] 6.8058158 3.1444084 7.2227652 0.8440180 0.8440180 7.2227652 6.0578751 456s [253] 0.1731496 7.2227652 6.8058158 6.8058158 7.2227652 6.8058158 6.0578751 456s [260] 6.8058158 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 0.8440180 456s [267] 6.8058158 3.1444084 3.1444084 0.8440180 3.1444084 0.8440180 0.0000000 456s [274] 3.1444084 0.8440180 0.8440180 0.1731496 6.0578751 6.0578751 0.8440180 456s [281] 0.0000000 0.0000000 0.0000000 6.0578751 0.0000000 3.1444084 3.1444084 456s [288] 0.0000000 0.8440180 6.0578751 0.0000000 6.0578751 7.2227652 0.8440180 456s [295] 7.2227652 6.8058158 0.8440180 0.1731496 7.2227652 7.2227652 0.0000000 456s [302] 6.0578751 6.8058158 7.2227652 0.0000000 6.0578751 6.0578751 6.8058158 456s [309] 0.0000000 0.8440180 6.0578751 6.8058158 6.8058158 3.1444084 0.8440180 456s [316] 6.8058158 3.1444084 7.2227652 6.0578751 0.8440180 3.1444084 0.8440180 456s [323] 7.2227652 6.0578751 6.0578751 7.2227652 3.1444084 6.0578751 6.8058158 456s [330] 0.8440180 0.8440180 6.8058158 6.8058158 7.2227652 0.8440180 3.1444084 456s [337] 3.1444084 6.0578751 6.0578751 0.0000000 3.1444084 6.8058158 0.8440180 456s [344] 3.1444084 6.0578751 7.2227652 3.1444084 3.1444084 0.1731496 6.0578751 456s [351] 7.2227652 7.2227652 3.1444084 6.0578751 3.1444084 6.0578751 3.1444084 456s [358] 6.0578751 3.1444084 7.2227652 0.8440180 3.1444084 6.8058158 0.8440180 456s [365] 3.1444084 0.1731496 6.8058158 3.1444084 6.8058158 7.2227652 3.1444084 456s [372] 6.8058158 6.8058158 3.1444084 0.0000000 0.8440180 0.8440180 6.8058158 456s [379] 0.0000000 7.2227652 0.8440180 0.8440180 6.0578751 3.1444084 0.8440180 456s [386] 7.2227652 3.1444084 7.2227652 6.8058158 3.1444084 3.1444084 6.8058158 456s [393] 6.0578751 3.1444084 6.8058158 0.0000000 6.8058158 0.8440180 0.0000000 456s [400] 3.1444084 6.8058158 0.8440180 6.0578751 6.0578751 0.1731496 6.0578751 456s [407] 0.8440180 3.1444084 0.8440180 3.1444084 3.1444084 6.8058158 0.8440180 456s [414] 6.8058158 7.2227652 0.0000000 6.8058158 0.8440180 0.0000000 7.2227652 456s [421] 6.8058158 3.1444084 3.1444084 6.8058158 6.8058158 6.0578751 6.0578751 456s [428] 6.0578751 7.2227652 0.1731496 7.2227652 6.8058158 0.0000000 3.1444084 456s [435] 7.2227652 6.8058158 6.8058158 0.8440180 0.0000000 3.1444084 7.2227652 456s [442] 6.8058158 6.0578751 3.1444084 6.0578751 7.2227652 6.0578751 7.2227652 456s [449] 0.0000000 7.2227652 7.2227652 0.8440180 6.0578751 6.8058158 0.0000000 456s [456] 0.8440180 6.0578751 0.1731496 3.1444084 7.2227652 7.2227652 6.0578751 456s [463] 6.0578751 3.1444084 0.1731496 7.2227652 6.8058158 0.8440180 0.0000000 456s [470] 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 7.2227652 0.8440180 456s [477] 3.1444084 7.2227652 7.2227652 0.1731496 3.1444084 7.2227652 7.2227652 456s [484] 3.1444084 6.8058158 0.0000000 7.2227652 6.0578751 0.8440180 3.1444084 456s [491] 7.2227652 7.2227652 6.0578751 3.1444084 7.2227652 6.0578751 0.0000000 456s [498] 0.8440180 6.0578751 6.8058158 3.1444084 6.0578751 0.0000000 7.2227652 456s [505] 3.1444084 0.0000000 0.8440180 7.2227652 6.8058158 6.8058158 3.1444084 456s [512] 6.8058158 0.1731496 0.0000000 3.1444084 3.1444084 3.1444084 6.8058158 456s [519] 6.8058158 0.0000000 6.8058158 6.8058158 3.1444084 7.2227652 3.1444084 456s [526] 0.8440180 0.8440180 7.2227652 6.0578751 6.0578751 3.1444084 6.8058158 456s [533] 7.2227652 6.0578751 6.8058158 3.1444084 3.1444084 3.1444084 7.2227652 456s [540] 0.0000000 0.0000000 6.8058158 3.1444084 0.1731496 0.0000000 6.0578751 456s [547] 7.2227652 6.0578751 6.0578751 7.2227652 6.0578751 6.0578751 6.8058158 456s [554] 0.0000000 0.0000000 3.1444084 6.0578751 7.2227652 7.2227652 3.1444084 456s [561] 3.1444084 6.8058158 7.2227652 6.8058158 6.8058158 0.0000000 6.8058158 456s [568] 3.1444084 7.2227652 0.8440180 0.0000000 3.1444084 0.8440180 6.8058158 456s [575] 7.2227652 3.1444084 6.0578751 0.8440180 6.8058158 3.1444084 0.0000000 456s [582] 7.2227652 6.8058158 0.8440180 6.0578751 3.1444084 6.8058158 0.8440180 456s [589] 6.0578751 456s 456s $se.fit 456s [1] 0.7643614 0.6580335 0.7488551 0.7643614 0.7997224 0.6580335 0.7488551 456s [8] 0.7997224 0.7643614 0.0000000 0.7643614 0.7643614 0.7488551 0.7997224 456s [15] 0.4790120 0.0000000 0.7643614 0.7997224 0.7997224 0.0000000 0.7488551 456s [22] 0.0000000 0.7488551 0.6580335 0.6580335 0.7997224 0.6580335 0.6580335 456s [29] 0.7997224 0.7643614 0.7488551 0.6580335 0.7997224 0.7997224 0.7997224 456s [36] 0.0000000 0.0000000 0.7997224 0.6580335 0.7997224 0.7997224 0.4790120 456s [43] 0.7997224 0.7643614 0.7997224 0.7643614 0.4790120 0.7488551 0.4790120 456s [50] 0.4790120 0.0000000 0.7488551 0.6580335 0.6580335 0.7488551 0.7997224 456s [57] 0.7488551 0.6580335 0.4790120 0.4790120 0.7997224 0.0000000 0.7488551 456s [64] 0.6580335 0.6580335 0.6580335 0.0000000 0.7488551 0.7997224 0.7643614 456s [71] 0.0000000 0.4790120 0.4790120 0.6580335 0.7997224 0.7997224 0.7643614 456s [78] 0.0000000 0.7643614 0.6580335 0.6580335 0.7997224 0.7997224 0.7997224 456s [85] 0.7997224 0.7488551 0.6580335 0.4790120 0.0000000 0.4790120 0.7488551 456s [92] 0.6580335 0.7997224 0.7488551 0.7643614 0.6580335 0.7643614 0.6580335 456s [99] 0.6580335 0.6580335 0.7997224 0.7643614 0.6580335 0.0000000 0.7643614 456s [106] 0.6580335 0.0000000 0.6580335 0.7997224 0.7997224 0.4790120 0.6580335 456s [113] 0.7643614 0.7997224 0.1680259 0.7643614 0.7643614 0.0000000 0.6580335 456s [120] 0.0000000 0.0000000 0.6580335 0.1680259 0.4790120 0.0000000 0.7643614 456s [127] 0.6580335 0.7997224 0.7643614 0.4790120 0.6580335 0.4790120 0.7488551 456s [134] 0.6580335 0.7997224 0.7643614 0.6580335 0.7488551 0.6580335 0.1680259 456s [141] 0.6580335 0.6580335 0.4790120 0.6580335 0.7643614 0.7488551 0.6580335 456s [148] 0.7997224 0.7997224 0.0000000 0.7643614 0.7997224 0.0000000 0.7997224 456s [155] 0.6580335 0.7488551 0.6580335 0.0000000 0.0000000 0.4790120 0.7997224 456s [162] 0.0000000 0.1680259 0.7997224 0.7997224 0.7643614 0.0000000 0.4790120 456s [169] 0.0000000 0.7997224 0.7997224 0.7643614 0.7643614 0.0000000 0.7488551 456s [176] 0.4790120 0.0000000 0.7643614 0.0000000 0.7488551 0.0000000 0.7997224 456s [183] 0.7643614 0.7643614 0.7997224 0.7997224 0.1680259 0.7488551 0.7997224 456s [190] 0.4790120 0.7488551 0.7488551 0.4790120 0.0000000 0.7488551 0.7997224 456s [197] 0.7488551 0.7488551 0.1680259 0.7997224 0.0000000 0.7488551 0.7997224 456s [204] 0.6580335 0.6580335 0.7488551 0.6580335 0.7488551 0.4790120 0.7643614 456s [211] 0.7997224 0.7997224 0.7997224 0.0000000 0.0000000 0.7643614 0.7643614 456s [218] 0.7997224 0.7997224 0.1680259 0.7488551 0.7488551 0.0000000 0.4790120 456s [225] 0.7488551 0.4790120 0.7997224 0.4790120 0.0000000 0.7488551 0.7997224 456s [232] 0.6580335 0.6580335 0.7997224 0.4790120 0.7643614 0.4790120 0.0000000 456s [239] 0.0000000 0.6580335 0.7488551 0.6580335 0.7643614 0.7997224 0.7488551 456s [246] 0.6580335 0.7997224 0.7488551 0.4790120 0.4790120 0.7488551 0.7643614 456s [253] 0.1680259 0.7488551 0.6580335 0.6580335 0.7488551 0.6580335 0.7643614 456s [260] 0.6580335 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.4790120 456s [267] 0.6580335 0.7997224 0.7997224 0.4790120 0.7997224 0.4790120 0.0000000 456s [274] 0.7997224 0.4790120 0.4790120 0.1680259 0.7643614 0.7643614 0.4790120 456s [281] 0.0000000 0.0000000 0.0000000 0.7643614 0.0000000 0.7997224 0.7997224 456s [288] 0.0000000 0.4790120 0.7643614 0.0000000 0.7643614 0.7488551 0.4790120 456s [295] 0.7488551 0.6580335 0.4790120 0.1680259 0.7488551 0.7488551 0.0000000 456s [302] 0.7643614 0.6580335 0.7488551 0.0000000 0.7643614 0.7643614 0.6580335 456s [309] 0.0000000 0.4790120 0.7643614 0.6580335 0.6580335 0.7997224 0.4790120 456s [316] 0.6580335 0.7997224 0.7488551 0.7643614 0.4790120 0.7997224 0.4790120 456s [323] 0.7488551 0.7643614 0.7643614 0.7488551 0.7997224 0.7643614 0.6580335 456s [330] 0.4790120 0.4790120 0.6580335 0.6580335 0.7488551 0.4790120 0.7997224 456s [337] 0.7997224 0.7643614 0.7643614 0.0000000 0.7997224 0.6580335 0.4790120 456s [344] 0.7997224 0.7643614 0.7488551 0.7997224 0.7997224 0.1680259 0.7643614 456s [351] 0.7488551 0.7488551 0.7997224 0.7643614 0.7997224 0.7643614 0.7997224 456s [358] 0.7643614 0.7997224 0.7488551 0.4790120 0.7997224 0.6580335 0.4790120 456s [365] 0.7997224 0.1680259 0.6580335 0.7997224 0.6580335 0.7488551 0.7997224 456s [372] 0.6580335 0.6580335 0.7997224 0.0000000 0.4790120 0.4790120 0.6580335 456s [379] 0.0000000 0.7488551 0.4790120 0.4790120 0.7643614 0.7997224 0.4790120 456s [386] 0.7488551 0.7997224 0.7488551 0.6580335 0.7997224 0.7997224 0.6580335 456s [393] 0.7643614 0.7997224 0.6580335 0.0000000 0.6580335 0.4790120 0.0000000 456s [400] 0.7997224 0.6580335 0.4790120 0.7643614 0.7643614 0.1680259 0.7643614 456s [407] 0.4790120 0.7997224 0.4790120 0.7997224 0.7997224 0.6580335 0.4790120 456s [414] 0.6580335 0.7488551 0.0000000 0.6580335 0.4790120 0.0000000 0.7488551 456s [421] 0.6580335 0.7997224 0.7997224 0.6580335 0.6580335 0.7643614 0.7643614 456s [428] 0.7643614 0.7488551 0.1680259 0.7488551 0.6580335 0.0000000 0.7997224 456s [435] 0.7488551 0.6580335 0.6580335 0.4790120 0.0000000 0.7997224 0.7488551 456s [442] 0.6580335 0.7643614 0.7997224 0.7643614 0.7488551 0.7643614 0.7488551 456s [449] 0.0000000 0.7488551 0.7488551 0.4790120 0.7643614 0.6580335 0.0000000 456s [456] 0.4790120 0.7643614 0.1680259 0.7997224 0.7488551 0.7488551 0.7643614 456s [463] 0.7643614 0.7997224 0.1680259 0.7488551 0.6580335 0.4790120 0.0000000 456s [470] 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.7488551 0.4790120 456s [477] 0.7997224 0.7488551 0.7488551 0.1680259 0.7997224 0.7488551 0.7488551 456s [484] 0.7997224 0.6580335 0.0000000 0.7488551 0.7643614 0.4790120 0.7997224 456s [491] 0.7488551 0.7488551 0.7643614 0.7997224 0.7488551 0.7643614 0.0000000 456s [498] 0.4790120 0.7643614 0.6580335 0.7997224 0.7643614 0.0000000 0.7488551 456s [505] 0.7997224 0.0000000 0.4790120 0.7488551 0.6580335 0.6580335 0.7997224 456s [512] 0.6580335 0.1680259 0.0000000 0.7997224 0.7997224 0.7997224 0.6580335 456s [519] 0.6580335 0.0000000 0.6580335 0.6580335 0.7997224 0.7488551 0.7997224 456s [526] 0.4790120 0.4790120 0.7488551 0.7643614 0.7643614 0.7997224 0.6580335 456s [533] 0.7488551 0.7643614 0.6580335 0.7997224 0.7997224 0.7997224 0.7488551 456s [540] 0.0000000 0.0000000 0.6580335 0.7997224 0.1680259 0.0000000 0.7643614 456s [547] 0.7488551 0.7643614 0.7643614 0.7488551 0.7643614 0.7643614 0.6580335 456s [554] 0.0000000 0.0000000 0.7997224 0.7643614 0.7488551 0.7488551 0.7997224 456s [561] 0.7997224 0.6580335 0.7488551 0.6580335 0.6580335 0.0000000 0.6580335 456s [568] 0.7997224 0.7488551 0.4790120 0.0000000 0.7997224 0.4790120 0.6580335 456s [575] 0.7488551 0.7997224 0.7643614 0.4790120 0.6580335 0.7997224 0.0000000 456s [582] 0.7488551 0.6580335 0.4790120 0.7643614 0.7997224 0.6580335 0.4790120 456s [589] 0.7643614 456s 456s $fit 456s [1] 16.85434 17.60229 18.01923 16.85434 13.94088 17.60229 18.01923 13.94088 456s [9] 16.85434 10.79647 16.85434 16.85434 18.01923 13.94088 11.64049 10.79647 456s [17] 16.85434 13.94088 13.94088 10.79647 18.01923 10.79647 18.01923 17.60229 456s [25] 17.60229 13.94088 17.60229 17.60229 13.94088 16.85434 18.01923 17.60229 456s [33] 13.94088 13.94088 13.94088 10.79647 10.79647 13.94088 17.60229 13.94088 456s [41] 13.94088 11.64049 13.94088 16.85434 13.94088 16.85434 11.64049 18.01923 456s [49] 11.64049 11.64049 10.79647 18.01923 17.60229 17.60229 18.01923 13.94088 456s [57] 18.01923 17.60229 11.64049 11.64049 13.94088 10.79647 18.01923 17.60229 456s [65] 17.60229 17.60229 10.79647 18.01923 13.94088 16.85434 10.79647 11.64049 456s [73] 11.64049 17.60229 13.94088 13.94088 16.85434 10.79647 16.85434 17.60229 456s [81] 17.60229 13.94088 13.94088 13.94088 13.94088 18.01923 17.60229 11.64049 456s [89] 10.79647 11.64049 18.01923 17.60229 13.94088 18.01923 16.85434 17.60229 456s [97] 16.85434 17.60229 17.60229 17.60229 13.94088 16.85434 17.60229 10.79647 456s [105] 16.85434 17.60229 10.79647 17.60229 13.94088 13.94088 11.64049 17.60229 456s [113] 16.85434 13.94088 10.96962 16.85434 16.85434 10.79647 17.60229 10.79647 456s [121] 10.79647 17.60229 10.96962 11.64049 10.79647 16.85434 17.60229 13.94088 456s [129] 16.85434 11.64049 17.60229 11.64049 18.01923 17.60229 13.94088 16.85434 456s [137] 17.60229 18.01923 17.60229 10.96962 17.60229 17.60229 11.64049 17.60229 456s [145] 16.85434 18.01923 17.60229 13.94088 13.94088 10.79647 16.85434 13.94088 456s [153] 10.79647 13.94088 17.60229 18.01923 17.60229 10.79647 10.79647 11.64049 456s [161] 13.94088 10.79647 10.96962 13.94088 13.94088 16.85434 10.79647 11.64049 456s [169] 10.79647 13.94088 13.94088 16.85434 16.85434 10.79647 18.01923 11.64049 456s [177] 10.79647 16.85434 10.79647 18.01923 10.79647 13.94088 16.85434 16.85434 456s [185] 13.94088 13.94088 10.96962 18.01923 13.94088 11.64049 18.01923 18.01923 456s [193] 11.64049 10.79647 18.01923 13.94088 18.01923 18.01923 10.96962 13.94088 456s [201] 10.79647 18.01923 13.94088 17.60229 17.60229 18.01923 17.60229 18.01923 456s [209] 11.64049 16.85434 13.94088 13.94088 13.94088 10.79647 10.79647 16.85434 456s [217] 16.85434 13.94088 13.94088 10.96962 18.01923 18.01923 10.79647 11.64049 456s [225] 18.01923 11.64049 13.94088 11.64049 10.79647 18.01923 13.94088 17.60229 456s [233] 17.60229 13.94088 11.64049 16.85434 11.64049 10.79647 10.79647 17.60229 456s [241] 18.01923 17.60229 16.85434 13.94088 18.01923 17.60229 13.94088 18.01923 456s [249] 11.64049 11.64049 18.01923 16.85434 10.96962 18.01923 17.60229 17.60229 456s [257] 18.01923 17.60229 16.85434 17.60229 11.64049 17.60229 17.60229 18.01923 456s [265] 16.85434 11.64049 17.60229 13.94088 13.94088 11.64049 13.94088 11.64049 456s [273] 10.79647 13.94088 11.64049 11.64049 10.96962 16.85434 16.85434 11.64049 456s [281] 10.79647 10.79647 10.79647 16.85434 10.79647 13.94088 13.94088 10.79647 456s [289] 11.64049 16.85434 10.79647 16.85434 18.01923 11.64049 18.01923 17.60229 456s [297] 11.64049 10.96962 18.01923 18.01923 10.79647 16.85434 17.60229 18.01923 456s [305] 10.79647 16.85434 16.85434 17.60229 10.79647 11.64049 16.85434 17.60229 456s [313] 17.60229 13.94088 11.64049 17.60229 13.94088 18.01923 16.85434 11.64049 456s [321] 13.94088 11.64049 18.01923 16.85434 16.85434 18.01923 13.94088 16.85434 456s [329] 17.60229 11.64049 11.64049 17.60229 17.60229 18.01923 11.64049 13.94088 456s [337] 13.94088 16.85434 16.85434 10.79647 13.94088 17.60229 11.64049 13.94088 456s [345] 16.85434 18.01923 13.94088 13.94088 10.96962 16.85434 18.01923 18.01923 456s [353] 13.94088 16.85434 13.94088 16.85434 13.94088 16.85434 13.94088 18.01923 456s [361] 11.64049 13.94088 17.60229 11.64049 13.94088 10.96962 17.60229 13.94088 456s [369] 17.60229 18.01923 13.94088 17.60229 17.60229 13.94088 10.79647 11.64049 456s [377] 11.64049 17.60229 10.79647 18.01923 11.64049 11.64049 16.85434 13.94088 456s [385] 11.64049 18.01923 13.94088 18.01923 17.60229 13.94088 13.94088 17.60229 456s [393] 16.85434 13.94088 17.60229 10.79647 17.60229 11.64049 10.79647 13.94088 456s [401] 17.60229 11.64049 16.85434 16.85434 10.96962 16.85434 11.64049 13.94088 456s [409] 11.64049 13.94088 13.94088 17.60229 11.64049 17.60229 18.01923 10.79647 456s [417] 17.60229 11.64049 10.79647 18.01923 17.60229 13.94088 13.94088 17.60229 456s [425] 17.60229 16.85434 16.85434 16.85434 18.01923 10.96962 18.01923 17.60229 456s [433] 10.79647 13.94088 18.01923 17.60229 17.60229 11.64049 10.79647 13.94088 456s [441] 18.01923 17.60229 16.85434 13.94088 16.85434 18.01923 16.85434 18.01923 456s [449] 10.79647 18.01923 18.01923 11.64049 16.85434 17.60229 10.79647 11.64049 456s [457] 16.85434 10.96962 13.94088 18.01923 18.01923 16.85434 16.85434 13.94088 456s [465] 10.96962 18.01923 17.60229 11.64049 10.79647 11.64049 17.60229 17.60229 456s [473] 18.01923 16.85434 18.01923 11.64049 13.94088 18.01923 18.01923 10.96962 456s [481] 13.94088 18.01923 18.01923 13.94088 17.60229 10.79647 18.01923 16.85434 456s [489] 11.64049 13.94088 18.01923 18.01923 16.85434 13.94088 18.01923 16.85434 456s [497] 10.79647 11.64049 16.85434 17.60229 13.94088 16.85434 10.79647 18.01923 456s [505] 13.94088 10.79647 11.64049 18.01923 17.60229 17.60229 13.94088 17.60229 456s [513] 10.96962 10.79647 13.94088 13.94088 13.94088 17.60229 17.60229 10.79647 456s [521] 17.60229 17.60229 13.94088 18.01923 13.94088 11.64049 11.64049 18.01923 456s [529] 16.85434 16.85434 13.94088 17.60229 18.01923 16.85434 17.60229 13.94088 456s [537] 13.94088 13.94088 18.01923 10.79647 10.79647 17.60229 13.94088 10.96962 456s [545] 10.79647 16.85434 18.01923 16.85434 16.85434 18.01923 16.85434 16.85434 456s [553] 17.60229 10.79647 10.79647 13.94088 16.85434 18.01923 18.01923 13.94088 456s [561] 13.94088 17.60229 18.01923 17.60229 17.60229 10.79647 17.60229 13.94088 456s [569] 18.01923 11.64049 10.79647 13.94088 11.64049 17.60229 18.01923 13.94088 456s [577] 16.85434 11.64049 17.60229 13.94088 10.79647 18.01923 17.60229 11.64049 456s [585] 16.85434 13.94088 17.60229 11.64049 16.85434 456s 456s $se.fit 456s [1] 0.4716508 0.3621952 0.5408090 0.4716508 0.4610877 0.3621952 0.5408090 456s [8] 0.4610877 0.4716508 0.5653200 0.4716508 0.4716508 0.5408090 0.4610877 456s [15] 0.3763389 0.5653200 0.4716508 0.4610877 0.4610877 0.5653200 0.5408090 456s [22] 0.5653200 0.5408090 0.3621952 0.3621952 0.4610877 0.3621952 0.3621952 456s [29] 0.4610877 0.4716508 0.5408090 0.3621952 0.4610877 0.4610877 0.4610877 456s [36] 0.5653200 0.5653200 0.4610877 0.3621952 0.4610877 0.4610877 0.3763389 456s [43] 0.4610877 0.4716508 0.4610877 0.4716508 0.3763389 0.5408090 0.3763389 456s [50] 0.3763389 0.5653200 0.5408090 0.3621952 0.3621952 0.5408090 0.4610877 456s [57] 0.5408090 0.3621952 0.3763389 0.3763389 0.4610877 0.5653200 0.5408090 456s [64] 0.3621952 0.3621952 0.3621952 0.5653200 0.5408090 0.4610877 0.4716508 456s [71] 0.5653200 0.3763389 0.3763389 0.3621952 0.4610877 0.4610877 0.4716508 456s [78] 0.5653200 0.4716508 0.3621952 0.3621952 0.4610877 0.4610877 0.4610877 456s [85] 0.4610877 0.5408090 0.3621952 0.3763389 0.5653200 0.3763389 0.5408090 456s [92] 0.3621952 0.4610877 0.5408090 0.4716508 0.3621952 0.4716508 0.3621952 456s [99] 0.3621952 0.3621952 0.4610877 0.4716508 0.3621952 0.5653200 0.4716508 456s [106] 0.3621952 0.5653200 0.3621952 0.4610877 0.4610877 0.3763389 0.3621952 456s [113] 0.4716508 0.4610877 0.4616804 0.4716508 0.4716508 0.5653200 0.3621952 456s [120] 0.5653200 0.5653200 0.3621952 0.4616804 0.3763389 0.5653200 0.4716508 456s [127] 0.3621952 0.4610877 0.4716508 0.3763389 0.3621952 0.3763389 0.5408090 456s [134] 0.3621952 0.4610877 0.4716508 0.3621952 0.5408090 0.3621952 0.4616804 456s [141] 0.3621952 0.3621952 0.3763389 0.3621952 0.4716508 0.5408090 0.3621952 456s [148] 0.4610877 0.4610877 0.5653200 0.4716508 0.4610877 0.5653200 0.4610877 456s [155] 0.3621952 0.5408090 0.3621952 0.5653200 0.5653200 0.3763389 0.4610877 456s [162] 0.5653200 0.4616804 0.4610877 0.4610877 0.4716508 0.5653200 0.3763389 456s [169] 0.5653200 0.4610877 0.4610877 0.4716508 0.4716508 0.5653200 0.5408090 456s [176] 0.3763389 0.5653200 0.4716508 0.5653200 0.5408090 0.5653200 0.4610877 456s [183] 0.4716508 0.4716508 0.4610877 0.4610877 0.4616804 0.5408090 0.4610877 456s [190] 0.3763389 0.5408090 0.5408090 0.3763389 0.5653200 0.5408090 0.4610877 456s [197] 0.5408090 0.5408090 0.4616804 0.4610877 0.5653200 0.5408090 0.4610877 456s [204] 0.3621952 0.3621952 0.5408090 0.3621952 0.5408090 0.3763389 0.4716508 456s [211] 0.4610877 0.4610877 0.4610877 0.5653200 0.5653200 0.4716508 0.4716508 456s [218] 0.4610877 0.4610877 0.4616804 0.5408090 0.5408090 0.5653200 0.3763389 456s [225] 0.5408090 0.3763389 0.4610877 0.3763389 0.5653200 0.5408090 0.4610877 456s [232] 0.3621952 0.3621952 0.4610877 0.3763389 0.4716508 0.3763389 0.5653200 456s [239] 0.5653200 0.3621952 0.5408090 0.3621952 0.4716508 0.4610877 0.5408090 456s [246] 0.3621952 0.4610877 0.5408090 0.3763389 0.3763389 0.5408090 0.4716508 456s [253] 0.4616804 0.5408090 0.3621952 0.3621952 0.5408090 0.3621952 0.4716508 456s [260] 0.3621952 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.3763389 456s [267] 0.3621952 0.4610877 0.4610877 0.3763389 0.4610877 0.3763389 0.5653200 456s [274] 0.4610877 0.3763389 0.3763389 0.4616804 0.4716508 0.4716508 0.3763389 456s [281] 0.5653200 0.5653200 0.5653200 0.4716508 0.5653200 0.4610877 0.4610877 456s [288] 0.5653200 0.3763389 0.4716508 0.5653200 0.4716508 0.5408090 0.3763389 456s [295] 0.5408090 0.3621952 0.3763389 0.4616804 0.5408090 0.5408090 0.5653200 456s [302] 0.4716508 0.3621952 0.5408090 0.5653200 0.4716508 0.4716508 0.3621952 456s [309] 0.5653200 0.3763389 0.4716508 0.3621952 0.3621952 0.4610877 0.3763389 456s [316] 0.3621952 0.4610877 0.5408090 0.4716508 0.3763389 0.4610877 0.3763389 456s [323] 0.5408090 0.4716508 0.4716508 0.5408090 0.4610877 0.4716508 0.3621952 456s [330] 0.3763389 0.3763389 0.3621952 0.3621952 0.5408090 0.3763389 0.4610877 456s [337] 0.4610877 0.4716508 0.4716508 0.5653200 0.4610877 0.3621952 0.3763389 456s [344] 0.4610877 0.4716508 0.5408090 0.4610877 0.4610877 0.4616804 0.4716508 456s [351] 0.5408090 0.5408090 0.4610877 0.4716508 0.4610877 0.4716508 0.4610877 456s [358] 0.4716508 0.4610877 0.5408090 0.3763389 0.4610877 0.3621952 0.3763389 456s [365] 0.4610877 0.4616804 0.3621952 0.4610877 0.3621952 0.5408090 0.4610877 456s [372] 0.3621952 0.3621952 0.4610877 0.5653200 0.3763389 0.3763389 0.3621952 456s [379] 0.5653200 0.5408090 0.3763389 0.3763389 0.4716508 0.4610877 0.3763389 456s [386] 0.5408090 0.4610877 0.5408090 0.3621952 0.4610877 0.4610877 0.3621952 456s [393] 0.4716508 0.4610877 0.3621952 0.5653200 0.3621952 0.3763389 0.5653200 456s [400] 0.4610877 0.3621952 0.3763389 0.4716508 0.4716508 0.4616804 0.4716508 456s [407] 0.3763389 0.4610877 0.3763389 0.4610877 0.4610877 0.3621952 0.3763389 456s [414] 0.3621952 0.5408090 0.5653200 0.3621952 0.3763389 0.5653200 0.5408090 456s [421] 0.3621952 0.4610877 0.4610877 0.3621952 0.3621952 0.4716508 0.4716508 456s [428] 0.4716508 0.5408090 0.4616804 0.5408090 0.3621952 0.5653200 0.4610877 456s [435] 0.5408090 0.3621952 0.3621952 0.3763389 0.5653200 0.4610877 0.5408090 456s [442] 0.3621952 0.4716508 0.4610877 0.4716508 0.5408090 0.4716508 0.5408090 456s [449] 0.5653200 0.5408090 0.5408090 0.3763389 0.4716508 0.3621952 0.5653200 456s [456] 0.3763389 0.4716508 0.4616804 0.4610877 0.5408090 0.5408090 0.4716508 456s [463] 0.4716508 0.4610877 0.4616804 0.5408090 0.3621952 0.3763389 0.5653200 456s [470] 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.5408090 0.3763389 456s [477] 0.4610877 0.5408090 0.5408090 0.4616804 0.4610877 0.5408090 0.5408090 456s [484] 0.4610877 0.3621952 0.5653200 0.5408090 0.4716508 0.3763389 0.4610877 456s [491] 0.5408090 0.5408090 0.4716508 0.4610877 0.5408090 0.4716508 0.5653200 456s [498] 0.3763389 0.4716508 0.3621952 0.4610877 0.4716508 0.5653200 0.5408090 456s [505] 0.4610877 0.5653200 0.3763389 0.5408090 0.3621952 0.3621952 0.4610877 456s [512] 0.3621952 0.4616804 0.5653200 0.4610877 0.4610877 0.4610877 0.3621952 456s [519] 0.3621952 0.5653200 0.3621952 0.3621952 0.4610877 0.5408090 0.4610877 456s [526] 0.3763389 0.3763389 0.5408090 0.4716508 0.4716508 0.4610877 0.3621952 456s [533] 0.5408090 0.4716508 0.3621952 0.4610877 0.4610877 0.4610877 0.5408090 456s [540] 0.5653200 0.5653200 0.3621952 0.4610877 0.4616804 0.5653200 0.4716508 456s [547] 0.5408090 0.4716508 0.4716508 0.5408090 0.4716508 0.4716508 0.3621952 456s [554] 0.5653200 0.5653200 0.4610877 0.4716508 0.5408090 0.5408090 0.4610877 456s [561] 0.4610877 0.3621952 0.5408090 0.3621952 0.3621952 0.5653200 0.3621952 456s [568] 0.4610877 0.5408090 0.3763389 0.5653200 0.4610877 0.3763389 0.3621952 456s [575] 0.5408090 0.4610877 0.4716508 0.3763389 0.3621952 0.4610877 0.5653200 456s [582] 0.5408090 0.3621952 0.3763389 0.4716508 0.4610877 0.3621952 0.3763389 456s [589] 0.4716508 456s 456s [1] 64.48518 456s [1] 3722.867 456s [1] 3722.867 456s Dose Response Model 456s 456s Model: betaMod 456s Fit-type: normal 456s 456s Residuals: 456s Min 1Q Median 3Q Max 456s -23.081 -4.023 0.069 3.767 16.317 456s 456s Coefficients with approx. stand. error: 456s Estimate Std. Error 456s e0 1.02e+01 0.82024 456s eMax 7.36e+00 0.69530 456s delta1 2.25e+00 0.60058 456s delta2 1.01e+00 0.33271 456s age 5.72e-04 0.00829 456s centergreen 7.41e-01 0.73739 456s centerred 8.30e-01 0.74509 456s centersilver 7.30e-01 0.70097 456s centeryellow 6.56e-01 0.73274 456s 456s Residual standard error: 5.65 456s Degrees of freedom: 580 456s 456s Formula: y ~ cbind(XX, betaMod(x, 0, 1, delta1, delta2, scl)) 456s 456s Parameters: 456s Estimate Std. Error t value Pr(>|t|) 456s delta1 2.253e+00 6.006e-01 3.751 0.000194 *** 456s delta2 1.006e+00 3.327e-01 3.025 0.002600 ** 456s .lin.(Intercept) 1.023e+01 8.202e-01 12.470 < 2e-16 *** 456s .lin.centergreen 7.409e-01 7.374e-01 1.005 0.315410 456s .lin.centerred 8.298e-01 7.451e-01 1.114 0.265866 456s .lin.centersilver 7.301e-01 7.010e-01 1.042 0.298051 456s .lin.centeryellow 6.562e-01 7.327e-01 0.896 0.370886 456s .lin.age 5.723e-04 8.288e-03 0.069 0.944970 456s .lin7 7.357e+00 6.953e-01 10.581 < 2e-16 *** 456s --- 456s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 456s 456s Residual standard error: 5.653 on 580 degrees of freedom 456s 456s Number of iterations to convergence: 6 456s Achieved convergence tolerance: 9.483e-06 456s 456s e0 eMax delta1 delta2 456s e0 0.672788555 -0.2729452008 2.029556e-01 8.893435e-02 456s eMax -0.272945201 0.4834404095 -4.411253e-02 1.212204e-02 456s delta1 0.202955602 -0.0441125317 3.606932e-01 1.869163e-01 456s delta2 0.088934352 0.0121220371 1.869163e-01 1.106931e-01 456s age -0.003530727 0.0001030079 4.984077e-05 7.767012e-05 456s centergreen -0.234450342 -0.0348602441 1.207912e-02 1.405608e-03 456s centerred -0.253662862 -0.0121021694 6.628052e-04 -2.474391e-03 456s centersilver -0.222055302 -0.0379891034 1.347032e-02 4.810797e-03 456s centeryellow -0.242096858 -0.0036488338 1.244170e-02 2.099443e-03 456s age centergreen centerred centersilver 456s e0 -3.530727e-03 -0.2344503416 -0.2536628616 -2.220553e-01 456s eMax 1.030079e-04 -0.0348602441 -0.0121021694 -3.798910e-02 456s delta1 4.984077e-05 0.0120791216 0.0006628052 1.347032e-02 456s delta2 7.767012e-05 0.0014056079 -0.0024743906 4.810797e-03 456s age 6.868689e-05 0.0001513555 0.0001912581 -2.484136e-05 456s centergreen 1.513555e-04 0.5437481113 0.2513884520 2.524566e-01 456s centerred 1.912581e-04 0.2513884520 0.5551521388 2.504165e-01 456s centersilver -2.484136e-05 0.2524565639 0.2504164883 4.913597e-01 456s centeryellow -1.767809e-05 0.2510775793 0.2504115027 2.500668e-01 456s centeryellow 456s e0 -2.420969e-01 456s eMax -3.648834e-03 456s delta1 1.244170e-02 456s delta2 2.099443e-03 456s age -1.767809e-05 456s centergreen 2.510776e-01 456s centerred 2.504115e-01 456s centersilver 2.500668e-01 456s centeryellow 5.369021e-01 456s delta1 delta2 .lin.(Intercept) .lin.centergreen 456s delta1 3.606961e-01 1.869176e-01 0.202956175 0.0120792619 456s delta2 1.869176e-01 1.106938e-01 0.088934647 0.0014056742 456s .lin.(Intercept) 2.029562e-01 8.893465e-02 0.672787602 -0.2344503742 456s .lin.centergreen 1.207926e-02 1.405674e-03 -0.234450374 0.5437481112 456s .lin.centerred 6.627069e-04 -2.474441e-03 -0.253662950 0.2513884457 456s .lin.centersilver 1.347037e-02 4.810825e-03 -0.222055391 0.2524565593 456s .lin.centeryellow 1.244156e-02 2.099364e-03 -0.242097015 0.2510775716 456s .lin.age 4.984143e-05 7.767047e-05 -0.003530726 0.0001513556 456s .lin7 -4.411219e-02 1.212231e-02 -0.272944257 -0.0348602206 456s .lin.centerred .lin.centersilver .lin.centeryellow 456s delta1 0.0006627069 1.347037e-02 1.244156e-02 456s delta2 -0.0024744411 4.810825e-03 2.099364e-03 456s .lin.(Intercept) -0.2536629505 -2.220554e-01 -2.420970e-01 456s .lin.centergreen 0.2513884457 2.524566e-01 2.510776e-01 456s .lin.centerred 0.5551521364 2.504165e-01 2.504115e-01 456s .lin.centersilver 0.2504164813 4.913597e-01 2.500668e-01 456s .lin.centeryellow 0.2504114958 2.500668e-01 5.369021e-01 456s .lin.age 0.0001912581 -2.484131e-05 -1.767806e-05 456s .lin7 -0.0121021553 -3.798903e-02 -3.648776e-03 456s .lin.age .lin7 456s delta1 4.984143e-05 -0.0441121927 456s delta2 7.767047e-05 0.0121223132 456s .lin.(Intercept) -3.530726e-03 -0.2729442573 456s .lin.centergreen 1.513556e-04 -0.0348602206 456s .lin.centerred 1.912581e-04 -0.0121021553 456s .lin.centersilver -2.484131e-05 -0.0379890347 456s .lin.centeryellow -1.767806e-05 -0.0036487765 456s .lin.age 6.868689e-05 0.0001030081 456s .lin7 1.030081e-04 0.4834404610 456s $fit 456s [1] 0.000000 2.289162 456s 456s $se.fit 456s [1] 0.0000000 0.7519464 456s 456s $fit 456s [1] 10.91275 13.20191 456s 456s $se.fit 456s [1] 0.7364602 0.6423551 456s 456s [1] 65.39866 456s [1] -485.5937 456s [1] -485.5937 456s Dose Response Model 456s 456s Model: emax 456s Fit-type: normal 456s 456s Residuals: 456s Min 1Q Median 3Q Max 456s -0.0666 -0.0180 -0.0011 0.0193 0.0692 456s 456s Coefficients with approx. stand. error: 456s Estimate Std. Error 456s e0 -0.5830 6.00e-03 456s eMax 0.0163 3.36e-02 456s ed50 286.5994 1.91e+03 456s 456s Residual standard error: 0.0281 456s Degrees of freedom: 111 456s 456s Formula: y ~ emax(x, e0, emax, ed50) 456s 456s Parameters: 456s Estimate Std. Error t value Pr(>|t|) 456s e0 -0.58297 0.00600 -97.164 <2e-16 *** 456s emax 0.01632 0.03356 0.486 0.628 456s ed50 286.46623 1905.12541 0.150 0.881 456s --- 456s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 456s 456s Residual standard error: 0.02814 on 111 degrees of freedom 456s 456s Number of iterations to convergence: 8 456s Achieved convergence tolerance: 9.285e-06 456s 456s e0 eMax ed50 456s e0 3.599786e-05 -2.913476e-05 1.313843e+00 456s eMax -2.913476e-05 1.126946e-03 6.130312e+01 456s ed50 1.313843e+00 6.130312e+01 3.631673e+06 456s e0 emax ed50 456s e0 3.599786e-05 -2.914111e-05 1.313042e+00 456s emax -2.914111e-05 1.126337e-03 6.126751e+01 456s ed50 1.313042e+00 6.126751e+01 3.629503e+06 456s $fit 456s [1] 0.01155472 0.01155472 0.00000000 0.01155472 0.01155472 0.01155472 456s [7] 0.01056820 0.01056820 0.01056820 0.01155472 0.01239306 0.01056820 456s [13] 0.00000000 0.01239306 0.01155472 0.01056820 0.01056820 0.00000000 456s [19] 0.01155472 0.01212084 0.01212084 0.01056820 0.00000000 0.01155472 456s [25] 0.01056820 0.01056820 0.01155472 0.00000000 0.00000000 0.01155472 456s [31] 0.01056820 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 456s [37] 0.01155472 0.01212084 0.00000000 0.01155472 0.01239306 0.01155472 456s [43] 0.01056820 0.01056820 0.01155472 0.01155472 0.01155472 0.00000000 456s [49] 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 0.01239306 456s [55] 0.00000000 0.01056820 0.01155472 0.01056820 0.01239306 0.01239306 456s [61] 0.01056820 0.01239306 0.01056820 0.01155472 0.01212084 0.01155472 456s [67] 0.01056820 0.01056820 0.01239306 0.01056820 0.00000000 0.01155472 456s [73] 0.01239306 0.01155472 0.01155472 0.01056820 0.00000000 0.00000000 456s [79] 0.01155472 0.00000000 0.00000000 0.00000000 0.01155472 0.01155472 456s [85] 0.01056820 0.01056820 0.01155472 0.01056820 0.01155472 0.01155472 456s [91] 0.01212084 0.01155472 0.01212084 0.01056820 0.00000000 0.01155472 456s [97] 0.01155472 0.01056820 0.01155472 0.00000000 0.01155472 0.01155472 456s [103] 0.01056820 0.01056820 0.01056820 0.00000000 0.01155472 0.00000000 456s [109] 0.01056820 0.01056820 0.01155472 0.01056820 0.00000000 0.01056820 456s 456s $se.fit 456s [1] 0.006800657 0.006800657 0.000000000 0.006800657 0.006800657 0.006800657 456s [7] 0.007368990 0.007368990 0.007368990 0.006800657 0.008598392 0.007368990 456s [13] 0.000000000 0.008598392 0.006800657 0.007368990 0.007368990 0.000000000 456s [19] 0.006800657 0.007779856 0.007779856 0.007368990 0.000000000 0.006800657 456s [25] 0.007368990 0.007368990 0.006800657 0.000000000 0.000000000 0.006800657 456s [31] 0.007368990 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 456s [37] 0.006800657 0.007779856 0.000000000 0.006800657 0.008598392 0.006800657 456s [43] 0.007368990 0.007368990 0.006800657 0.006800657 0.006800657 0.000000000 456s [49] 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 0.008598392 456s [55] 0.000000000 0.007368990 0.006800657 0.007368990 0.008598392 0.008598392 456s [61] 0.007368990 0.008598392 0.007368990 0.006800657 0.007779856 0.006800657 456s [67] 0.007368990 0.007368990 0.008598392 0.007368990 0.000000000 0.006800657 456s [73] 0.008598392 0.006800657 0.006800657 0.007368990 0.000000000 0.000000000 456s [79] 0.006800657 0.000000000 0.000000000 0.000000000 0.006800657 0.006800657 456s [85] 0.007368990 0.007368990 0.006800657 0.007368990 0.006800657 0.006800657 456s [91] 0.007779856 0.006800657 0.007779856 0.007368990 0.000000000 0.006800657 456s [97] 0.006800657 0.007368990 0.006800657 0.000000000 0.006800657 0.006800657 456s [103] 0.007368990 0.007368990 0.007368990 0.000000000 0.006800657 0.000000000 456s [109] 0.007368990 0.007368990 0.006800657 0.007368990 0.000000000 0.007368990 456s 456s $fit 456s [1] -0.5714146 -0.5714146 -0.5829694 -0.5714146 -0.5714146 -0.5714146 456s [7] -0.5724012 -0.5724012 -0.5724012 -0.5714146 -0.5705763 -0.5724012 456s [13] -0.5829694 -0.5705763 -0.5714146 -0.5724012 -0.5724012 -0.5829694 456s [19] -0.5714146 -0.5708485 -0.5708485 -0.5724012 -0.5829694 -0.5714146 456s [25] -0.5724012 -0.5724012 -0.5714146 -0.5829694 -0.5829694 -0.5714146 456s [31] -0.5724012 -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 456s [37] -0.5714146 -0.5708485 -0.5829694 -0.5714146 -0.5705763 -0.5714146 456s [43] -0.5724012 -0.5724012 -0.5714146 -0.5714146 -0.5714146 -0.5829694 456s [49] -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 -0.5705763 456s [55] -0.5829694 -0.5724012 -0.5714146 -0.5724012 -0.5705763 -0.5705763 456s [61] -0.5724012 -0.5705763 -0.5724012 -0.5714146 -0.5708485 -0.5714146 456s [67] -0.5724012 -0.5724012 -0.5705763 -0.5724012 -0.5829694 -0.5714146 456s [73] -0.5705763 -0.5714146 -0.5714146 -0.5724012 -0.5829694 -0.5829694 456s [79] -0.5714146 -0.5829694 -0.5829694 -0.5829694 -0.5714146 -0.5714146 456s [85] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5714146 -0.5714146 456s [91] -0.5708485 -0.5714146 -0.5708485 -0.5724012 -0.5829694 -0.5714146 456s [97] -0.5714146 -0.5724012 -0.5714146 -0.5829694 -0.5714146 -0.5714146 456s [103] -0.5724012 -0.5724012 -0.5724012 -0.5829694 -0.5714146 -0.5829694 456s [109] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5829694 -0.5724012 456s 456s $se.fit 457s [1] 0.003169353 0.003169353 0.005999821 0.003169353 0.003169353 0.003169353 457s [7] 0.004290400 0.004290400 0.004290400 0.003169353 0.006190654 0.004290400 457s [13] 0.005999821 0.006190654 0.003169353 0.004290400 0.004290400 0.005999821 457s [19] 0.003169353 0.004963663 0.004963663 0.004290400 0.005999821 0.003169353 457s [25] 0.004290400 0.004290400 0.003169353 0.005999821 0.005999821 0.003169353 457s [31] 0.004290400 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 457s [37] 0.003169353 0.004963663 0.005999821 0.003169353 0.006190654 0.003169353 457s [43] 0.004290400 0.004290400 0.003169353 0.003169353 0.003169353 0.005999821 457s [49] 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 0.006190654 457s [55] 0.005999821 0.004290400 0.003169353 0.004290400 0.006190654 0.006190654 457s [61] 0.004290400 0.006190654 0.004290400 0.003169353 0.004963663 0.003169353 457s [67] 0.004290400 0.004290400 0.006190654 0.004290400 0.005999821 0.003169353 457s [73] 0.006190654 0.003169353 0.003169353 0.004290400 0.005999821 0.005999821 457s [79] 0.003169353 0.005999821 0.005999821 0.005999821 0.003169353 0.003169353 457s [85] 0.004290400 0.004290400 0.003169353 0.004290400 0.003169353 0.003169353 457s [91] 0.004963663 0.003169353 0.004963663 0.004290400 0.005999821 0.003169353 457s [97] 0.003169353 0.004290400 0.003169353 0.005999821 0.003169353 0.003169353 457s [103] 0.004290400 0.004290400 0.004290400 0.005999821 0.003169353 0.005999821 457s [109] 0.004290400 0.004290400 0.003169353 0.004290400 0.005999821 0.004290400 457s 457s [1] 126.5178 457s [1] -481.376 457s [1] -481.378 457s Dose Response Model 457s 457s Model: emax 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -0.07408 -0.01641 -0.00232 0.01807 0.07476 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -5.81e-01 8.97e-03 457s eMax 2.93e-02 9.13e-02 457s ed50 9.03e+02 5.00e+03 457s age -1.22e-04 1.06e-04 457s centergreen 1.07e-02 8.31e-03 457s centerred 9.27e-03 7.73e-03 457s centersilver 1.22e-03 8.91e-03 457s centeryellow -4.65e-03 8.50e-03 457s 457s Residual standard error: 0.0281 457s Degrees of freedom: 106 457s 457s Formula: y ~ cbind(XX, emax(x, 0, 1, ed50)) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s ed50 1.111e+03 6.451e+03 0.172 0.864 457s .lin.(Intercept) -5.813e-01 8.970e-03 -64.810 <2e-16 *** 457s .lin.centergreen 1.071e-02 8.309e-03 1.288 0.200 457s .lin.centerred 9.301e-03 7.726e-03 1.204 0.231 457s .lin.centersilver 1.196e-03 8.915e-03 0.134 0.894 457s .lin.centeryellow -4.665e-03 8.497e-03 -0.549 0.584 457s .lin.age -1.213e-04 1.057e-04 -1.148 0.254 457s .lin7 3.300e-02 1.170e-01 0.282 0.778 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 0.02808 on 106 degrees of freedom 457s 457s Number of iterations to convergence: 9 457s Achieved convergence tolerance: 7.042e-06 457s 457s e0 eMax ed50 age 457s e0 8.046543e-05 -3.844545e-05 2.355425e+00 -4.980066e-07 457s eMax -3.844545e-05 8.342573e-03 4.493061e+02 1.107091e-06 457s ed50 2.355425e+00 4.493061e+02 2.497229e+07 6.444381e-02 457s age -4.980066e-07 1.107091e-06 6.444381e-02 1.116195e-08 457s centergreen -1.978501e-05 6.446464e-05 4.524614e+00 -8.645567e-08 457s centerred -3.432079e-05 7.922237e-05 3.670388e+00 1.157010e-08 457s centersilver -1.753629e-05 -7.656779e-05 -3.796015e+00 -2.309374e-07 457s centeryellow -3.332560e-05 -5.044361e-05 -2.141277e+00 1.346886e-07 457s centergreen centerred centersilver centeryellow 457s e0 -1.978501e-05 -3.432079e-05 -1.753629e-05 -3.332560e-05 457s eMax 6.446464e-05 7.922237e-05 -7.656779e-05 -5.044361e-05 457s ed50 4.524614e+00 3.670388e+00 -3.796015e+00 -2.141277e+00 457s age -8.645567e-08 1.157010e-08 -2.309374e-07 1.346886e-07 457s centergreen 6.902160e-05 3.007695e-05 3.223410e-05 2.943878e-05 457s centerred 3.007695e-05 5.968790e-05 2.924362e-05 2.945739e-05 457s centersilver 3.223410e-05 2.924362e-05 7.947639e-05 2.823145e-05 457s centeryellow 2.943878e-05 2.945739e-05 2.823145e-05 7.219729e-05 457s ed50 .lin.(Intercept) .lin.centergreen 457s ed50 4.162110e+07 3.618133e+00 6.072528e+00 457s .lin.(Intercept) 3.618133e+00 8.045192e-05 -1.978784e-05 457s .lin.centergreen 6.072528e+00 -1.978784e-05 6.904772e-05 457s .lin.centerred 4.627133e+00 -3.432899e-05 3.008663e-05 457s .lin.centersilver -4.847154e+00 -1.752828e-05 3.222029e-05 457s .lin.centeryellow -2.727240e+00 -3.332482e-05 2.942341e-05 457s .lin.age 8.505296e-02 -4.980346e-07 -8.605363e-08 457s .lin7 7.456213e+02 -2.614221e-05 9.001669e-05 457s .lin.centerred .lin.centersilver .lin.centeryellow 457s ed50 4.627133e+00 -4.847154e+00 -2.727240e+00 457s .lin.(Intercept) -3.432899e-05 -1.752828e-05 -3.332482e-05 457s .lin.centergreen 3.008663e-05 3.222029e-05 2.942341e-05 457s .lin.centerred 5.968601e-05 2.924192e-05 2.945040e-05 457s .lin.centersilver 2.924192e-05 7.947836e-05 2.823890e-05 457s .lin.centeryellow 2.945040e-05 2.823890e-05 7.220391e-05 457s .lin.age 1.172543e-08 -2.311322e-07 1.344697e-07 457s .lin7 9.802604e-05 -9.643580e-05 -6.245218e-05 457s .lin.age .lin7 457s ed50 8.505296e-02 7.456213e+02 457s .lin.(Intercept) -4.980346e-07 -2.614221e-05 457s .lin.centergreen -8.605363e-08 9.001669e-05 457s .lin.centerred 1.172543e-08 9.802604e-05 457s .lin.centersilver -2.311322e-07 -9.643580e-05 457s .lin.centeryellow 1.344697e-07 -6.245218e-05 457s .lin.age 1.116761e-08 1.469361e-06 457s .lin7 1.469361e-06 1.368628e-02 457s $fit 457s [1] 0.000000000 0.002916944 457s 457s $se.fit 457s [1] 0.000000 0.005795 457s 457s $fit 457s [1] -0.5861913 -0.5832744 457s 457s $se.fit 457s [1] 0.008937545 0.009550033 457s 457s [1] 186.1323 457s [1] 2049.321 457s [1] 2049.321 457s Dose Response Model 457s 457s Model: sigEmax 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -13.6383 -2.8339 0.0791 3.0983 10.5294 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -10.92 0.555 457s eMax 17.17 3.430 457s ed50 379.22 148.679 457s h 1.38 0.349 457s 457s Residual standard error: 4.37 457s Degrees of freedom: 349 457s 457s Formula: y ~ sigEmax(x, e0, emax, ed50, h) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s e0 -10.9166 0.5552 -19.664 < 2e-16 *** 457s emax 17.1659 3.4296 5.005 8.87e-07 *** 457s ed50 379.2177 148.6773 2.551 0.0112 * 457s h 1.3754 0.3490 3.941 9.81e-05 *** 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 4.372 on 349 degrees of freedom 457s 457s Number of iterations to convergence: 4 457s Achieved convergence tolerance: 7.003e-07 457s 457s e0 eMax ed50 h 457s e0 0.30821303 -0.518459 6.111486 0.06026433 457s eMax -0.51845901 11.762554 468.796909 -1.10430572 457s ed50 6.11148598 468.796909 22105.398796 -40.29692932 457s h 0.06026433 -1.104306 -40.296929 0.12181039 457s e0 emax ed50 h 457s e0 0.30821303 -0.5184565 6.111572 0.06026446 457s emax -0.51845645 11.7623445 468.787220 -1.10429855 457s ed50 6.11157250 468.7872203 22104.945028 -40.29652906 457s h 0.06026446 -1.1042985 -40.296529 0.12181099 457s $fit 457s [1] 12.497935 12.497935 13.842361 2.869998 13.842361 13.842361 0.000000 457s [8] 0.000000 13.842361 2.869998 12.497935 12.497935 11.114421 12.497935 457s [15] 12.497935 12.497935 12.497935 12.497935 0.000000 12.497935 12.497935 457s [22] 0.000000 13.842361 13.842361 0.000000 0.000000 2.869998 12.497935 457s [29] 2.869998 2.869998 13.842361 0.000000 11.114421 12.497935 0.000000 457s [36] 13.842361 13.842361 12.497935 13.842361 2.869998 12.497935 12.497935 457s [43] 12.497935 2.869998 12.497935 12.497935 11.114421 12.497935 13.842361 457s [50] 13.842361 12.497935 0.000000 12.497935 12.497935 0.000000 12.497935 457s [57] 0.000000 13.842361 12.497935 2.869998 12.497935 13.842361 12.497935 457s [64] 13.842361 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 457s [71] 12.497935 2.869998 12.497935 12.497935 0.000000 13.842361 0.000000 457s [78] 13.842361 12.497935 12.497935 12.497935 12.497935 13.842361 2.869998 457s [85] 12.497935 12.497935 12.497935 0.000000 0.000000 0.000000 0.000000 457s [92] 2.869998 12.497935 12.497935 2.869998 12.497935 12.497935 2.869998 457s [99] 12.497935 0.000000 12.497935 0.000000 2.869998 2.869998 2.869998 457s [106] 12.497935 13.842361 12.497935 2.869998 0.000000 13.842361 2.869998 457s [113] 12.497935 0.000000 12.497935 0.000000 13.842361 12.497935 0.000000 457s [120] 12.497935 11.114421 13.842361 12.497935 12.497935 0.000000 12.497935 457s [127] 2.869998 13.842361 12.497935 13.842361 12.497935 2.869998 12.497935 457s [134] 12.497935 12.497935 12.497935 12.497935 13.842361 13.842361 0.000000 457s [141] 11.114421 12.497935 0.000000 12.497935 13.842361 12.497935 11.114421 457s [148] 12.497935 0.000000 0.000000 2.869998 13.842361 0.000000 2.869998 457s [155] 13.842361 2.869998 11.114421 11.114421 12.497935 0.000000 12.497935 457s [162] 12.497935 2.869998 2.869998 12.497935 12.497935 12.497935 12.497935 457s [169] 2.869998 11.114421 0.000000 13.842361 12.497935 11.114421 12.497935 457s [176] 13.842361 13.842361 12.497935 12.497935 12.497935 12.497935 12.497935 457s [183] 2.869998 13.842361 0.000000 12.497935 12.497935 12.497935 2.869998 457s [190] 13.842361 12.497935 13.842361 2.869998 13.842361 12.497935 12.497935 457s [197] 12.497935 0.000000 11.114421 2.869998 12.497935 2.869998 12.497935 457s [204] 0.000000 12.497935 13.842361 12.497935 13.842361 12.497935 2.869998 457s [211] 2.869998 12.497935 13.842361 13.842361 2.869998 0.000000 13.842361 457s [218] 12.497935 12.497935 0.000000 13.842361 12.497935 12.497935 0.000000 457s [225] 13.842361 11.114421 12.497935 2.869998 12.497935 0.000000 12.497935 457s [232] 12.497935 13.842361 0.000000 12.497935 12.497935 13.842361 0.000000 457s [239] 13.842361 13.842361 12.497935 13.842361 0.000000 2.869998 12.497935 457s [246] 13.842361 12.497935 12.497935 13.842361 2.869998 0.000000 0.000000 457s [253] 11.114421 2.869998 12.497935 2.869998 13.842361 0.000000 12.497935 457s [260] 12.497935 12.497935 12.497935 11.114421 0.000000 0.000000 0.000000 457s [267] 0.000000 0.000000 0.000000 12.497935 13.842361 13.842361 2.869998 457s [274] 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 13.842361 457s [281] 12.497935 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 457s [288] 11.114421 0.000000 12.497935 12.497935 0.000000 2.869998 12.497935 457s [295] 0.000000 0.000000 13.842361 0.000000 12.497935 13.842361 12.497935 457s [302] 12.497935 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 457s [309] 11.114421 2.869998 2.869998 0.000000 13.842361 0.000000 12.497935 457s [316] 2.869998 13.842361 0.000000 13.842361 11.114421 12.497935 0.000000 457s [323] 12.497935 12.497935 0.000000 13.842361 13.842361 13.842361 13.842361 457s [330] 11.114421 2.869998 0.000000 12.497935 0.000000 12.497935 13.842361 457s [337] 12.497935 12.497935 12.497935 12.497935 12.497935 13.842361 12.497935 457s [344] 2.869998 13.842361 13.842361 2.869998 11.114421 2.869998 12.497935 457s [351] 12.497935 12.497935 13.842361 457s 457s $se.fit 457s [1] 0.6365415 0.6365415 0.7457881 0.8126372 0.7457881 0.7457881 0.0000000 457s [8] 0.0000000 0.7457881 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 457s [15] 0.6365415 0.6365415 0.6365415 0.6365415 0.0000000 0.6365415 0.6365415 457s [22] 0.0000000 0.7457881 0.7457881 0.0000000 0.0000000 0.8126372 0.6365415 457s [29] 0.8126372 0.8126372 0.7457881 0.0000000 0.8003756 0.6365415 0.0000000 457s [36] 0.7457881 0.7457881 0.6365415 0.7457881 0.8126372 0.6365415 0.6365415 457s [43] 0.6365415 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 0.7457881 457s [50] 0.7457881 0.6365415 0.0000000 0.6365415 0.6365415 0.0000000 0.6365415 457s [57] 0.0000000 0.7457881 0.6365415 0.8126372 0.6365415 0.7457881 0.6365415 457s [64] 0.7457881 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 457s [71] 0.6365415 0.8126372 0.6365415 0.6365415 0.0000000 0.7457881 0.0000000 457s [78] 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.8126372 457s [85] 0.6365415 0.6365415 0.6365415 0.0000000 0.0000000 0.0000000 0.0000000 457s [92] 0.8126372 0.6365415 0.6365415 0.8126372 0.6365415 0.6365415 0.8126372 457s [99] 0.6365415 0.0000000 0.6365415 0.0000000 0.8126372 0.8126372 0.8126372 457s [106] 0.6365415 0.7457881 0.6365415 0.8126372 0.0000000 0.7457881 0.8126372 457s [113] 0.6365415 0.0000000 0.6365415 0.0000000 0.7457881 0.6365415 0.0000000 457s [120] 0.6365415 0.8003756 0.7457881 0.6365415 0.6365415 0.0000000 0.6365415 457s [127] 0.8126372 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 0.6365415 457s [134] 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.7457881 0.0000000 457s [141] 0.8003756 0.6365415 0.0000000 0.6365415 0.7457881 0.6365415 0.8003756 457s [148] 0.6365415 0.0000000 0.0000000 0.8126372 0.7457881 0.0000000 0.8126372 457s [155] 0.7457881 0.8126372 0.8003756 0.8003756 0.6365415 0.0000000 0.6365415 457s [162] 0.6365415 0.8126372 0.8126372 0.6365415 0.6365415 0.6365415 0.6365415 457s [169] 0.8126372 0.8003756 0.0000000 0.7457881 0.6365415 0.8003756 0.6365415 457s [176] 0.7457881 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 457s [183] 0.8126372 0.7457881 0.0000000 0.6365415 0.6365415 0.6365415 0.8126372 457s [190] 0.7457881 0.6365415 0.7457881 0.8126372 0.7457881 0.6365415 0.6365415 457s [197] 0.6365415 0.0000000 0.8003756 0.8126372 0.6365415 0.8126372 0.6365415 457s [204] 0.0000000 0.6365415 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 457s [211] 0.8126372 0.6365415 0.7457881 0.7457881 0.8126372 0.0000000 0.7457881 457s [218] 0.6365415 0.6365415 0.0000000 0.7457881 0.6365415 0.6365415 0.0000000 457s [225] 0.7457881 0.8003756 0.6365415 0.8126372 0.6365415 0.0000000 0.6365415 457s [232] 0.6365415 0.7457881 0.0000000 0.6365415 0.6365415 0.7457881 0.0000000 457s [239] 0.7457881 0.7457881 0.6365415 0.7457881 0.0000000 0.8126372 0.6365415 457s [246] 0.7457881 0.6365415 0.6365415 0.7457881 0.8126372 0.0000000 0.0000000 457s [253] 0.8003756 0.8126372 0.6365415 0.8126372 0.7457881 0.0000000 0.6365415 457s [260] 0.6365415 0.6365415 0.6365415 0.8003756 0.0000000 0.0000000 0.0000000 457s [267] 0.0000000 0.0000000 0.0000000 0.6365415 0.7457881 0.7457881 0.8126372 457s [274] 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 0.7457881 457s [281] 0.6365415 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 457s [288] 0.8003756 0.0000000 0.6365415 0.6365415 0.0000000 0.8126372 0.6365415 457s [295] 0.0000000 0.0000000 0.7457881 0.0000000 0.6365415 0.7457881 0.6365415 457s [302] 0.6365415 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 457s [309] 0.8003756 0.8126372 0.8126372 0.0000000 0.7457881 0.0000000 0.6365415 457s [316] 0.8126372 0.7457881 0.0000000 0.7457881 0.8003756 0.6365415 0.0000000 457s [323] 0.6365415 0.6365415 0.0000000 0.7457881 0.7457881 0.7457881 0.7457881 457s [330] 0.8003756 0.8126372 0.0000000 0.6365415 0.0000000 0.6365415 0.7457881 457s [337] 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.6365415 457s [344] 0.8126372 0.7457881 0.7457881 0.8126372 0.8003756 0.8126372 0.6365415 457s [351] 0.6365415 0.6365415 0.7457881 457s 457s $fit 457s [1] 1.5813420 1.5813420 2.9257679 -8.0465953 2.9257679 2.9257679 457s [7] -10.9165932 -10.9165932 2.9257679 -8.0465953 1.5813420 1.5813420 457s [13] 0.1978277 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 457s [19] -10.9165932 1.5813420 1.5813420 -10.9165932 2.9257679 2.9257679 457s [25] -10.9165932 -10.9165932 -8.0465953 1.5813420 -8.0465953 -8.0465953 457s [31] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 2.9257679 457s [37] 2.9257679 1.5813420 2.9257679 -8.0465953 1.5813420 1.5813420 457s [43] 1.5813420 -8.0465953 1.5813420 1.5813420 0.1978277 1.5813420 457s [49] 2.9257679 2.9257679 1.5813420 -10.9165932 1.5813420 1.5813420 457s [55] -10.9165932 1.5813420 -10.9165932 2.9257679 1.5813420 -8.0465953 457s [61] 1.5813420 2.9257679 1.5813420 2.9257679 2.9257679 1.5813420 457s [67] 1.5813420 -8.0465953 1.5813420 -8.0465953 1.5813420 -8.0465953 457s [73] 1.5813420 1.5813420 -10.9165932 2.9257679 -10.9165932 2.9257679 457s [79] 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 -8.0465953 457s [85] 1.5813420 1.5813420 1.5813420 -10.9165932 -10.9165932 -10.9165932 457s [91] -10.9165932 -8.0465953 1.5813420 1.5813420 -8.0465953 1.5813420 457s [97] 1.5813420 -8.0465953 1.5813420 -10.9165932 1.5813420 -10.9165932 457s [103] -8.0465953 -8.0465953 -8.0465953 1.5813420 2.9257679 1.5813420 457s [109] -8.0465953 -10.9165932 2.9257679 -8.0465953 1.5813420 -10.9165932 457s [115] 1.5813420 -10.9165932 2.9257679 1.5813420 -10.9165932 1.5813420 457s [121] 0.1978277 2.9257679 1.5813420 1.5813420 -10.9165932 1.5813420 457s [127] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 457s [133] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 457s [139] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 1.5813420 457s [145] 2.9257679 1.5813420 0.1978277 1.5813420 -10.9165932 -10.9165932 457s [151] -8.0465953 2.9257679 -10.9165932 -8.0465953 2.9257679 -8.0465953 457s [157] 0.1978277 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 457s [163] -8.0465953 -8.0465953 1.5813420 1.5813420 1.5813420 1.5813420 457s [169] -8.0465953 0.1978277 -10.9165932 2.9257679 1.5813420 0.1978277 457s [175] 1.5813420 2.9257679 2.9257679 1.5813420 1.5813420 1.5813420 457s [181] 1.5813420 1.5813420 -8.0465953 2.9257679 -10.9165932 1.5813420 457s [187] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 2.9257679 457s [193] -8.0465953 2.9257679 1.5813420 1.5813420 1.5813420 -10.9165932 457s [199] 0.1978277 -8.0465953 1.5813420 -8.0465953 1.5813420 -10.9165932 457s [205] 1.5813420 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 457s [211] -8.0465953 1.5813420 2.9257679 2.9257679 -8.0465953 -10.9165932 457s [217] 2.9257679 1.5813420 1.5813420 -10.9165932 2.9257679 1.5813420 457s [223] 1.5813420 -10.9165932 2.9257679 0.1978277 1.5813420 -8.0465953 457s [229] 1.5813420 -10.9165932 1.5813420 1.5813420 2.9257679 -10.9165932 457s [235] 1.5813420 1.5813420 2.9257679 -10.9165932 2.9257679 2.9257679 457s [241] 1.5813420 2.9257679 -10.9165932 -8.0465953 1.5813420 2.9257679 457s [247] 1.5813420 1.5813420 2.9257679 -8.0465953 -10.9165932 -10.9165932 457s [253] 0.1978277 -8.0465953 1.5813420 -8.0465953 2.9257679 -10.9165932 457s [259] 1.5813420 1.5813420 1.5813420 1.5813420 0.1978277 -10.9165932 457s [265] -10.9165932 -10.9165932 -10.9165932 -10.9165932 -10.9165932 1.5813420 457s [271] 2.9257679 2.9257679 -8.0465953 1.5813420 1.5813420 1.5813420 457s [277] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 1.5813420 457s [283] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 0.1978277 457s [289] -10.9165932 1.5813420 1.5813420 -10.9165932 -8.0465953 1.5813420 457s [295] -10.9165932 -10.9165932 2.9257679 -10.9165932 1.5813420 2.9257679 457s [301] 1.5813420 1.5813420 2.9257679 1.5813420 1.5813420 -8.0465953 457s [307] 1.5813420 -8.0465953 0.1978277 -8.0465953 -8.0465953 -10.9165932 457s [313] 2.9257679 -10.9165932 1.5813420 -8.0465953 2.9257679 -10.9165932 457s [319] 2.9257679 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 457s [325] -10.9165932 2.9257679 2.9257679 2.9257679 2.9257679 0.1978277 457s [331] -8.0465953 -10.9165932 1.5813420 -10.9165932 1.5813420 2.9257679 457s [337] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 457s [343] 1.5813420 -8.0465953 2.9257679 2.9257679 -8.0465953 0.1978277 457s [349] -8.0465953 1.5813420 1.5813420 1.5813420 2.9257679 457s 457s $se.fit 457s [1] 0.3179632 0.3179632 0.4944930 0.5940988 0.4944930 0.4944930 0.5551694 457s [8] 0.5551694 0.4944930 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 457s [15] 0.3179632 0.3179632 0.3179632 0.3179632 0.5551694 0.3179632 0.3179632 457s [22] 0.5551694 0.4944930 0.4944930 0.5551694 0.5551694 0.5940988 0.3179632 457s [29] 0.5940988 0.5940988 0.4944930 0.5551694 0.5590023 0.3179632 0.5551694 457s [36] 0.4944930 0.4944930 0.3179632 0.4944930 0.5940988 0.3179632 0.3179632 457s [43] 0.3179632 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 0.4944930 457s [50] 0.4944930 0.3179632 0.5551694 0.3179632 0.3179632 0.5551694 0.3179632 457s [57] 0.5551694 0.4944930 0.3179632 0.5940988 0.3179632 0.4944930 0.3179632 457s [64] 0.4944930 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 457s [71] 0.3179632 0.5940988 0.3179632 0.3179632 0.5551694 0.4944930 0.5551694 457s [78] 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.5940988 457s [85] 0.3179632 0.3179632 0.3179632 0.5551694 0.5551694 0.5551694 0.5551694 457s [92] 0.5940988 0.3179632 0.3179632 0.5940988 0.3179632 0.3179632 0.5940988 457s [99] 0.3179632 0.5551694 0.3179632 0.5551694 0.5940988 0.5940988 0.5940988 457s [106] 0.3179632 0.4944930 0.3179632 0.5940988 0.5551694 0.4944930 0.5940988 457s [113] 0.3179632 0.5551694 0.3179632 0.5551694 0.4944930 0.3179632 0.5551694 457s [120] 0.3179632 0.5590023 0.4944930 0.3179632 0.3179632 0.5551694 0.3179632 457s [127] 0.5940988 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 0.3179632 457s [134] 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.4944930 0.5551694 457s [141] 0.5590023 0.3179632 0.5551694 0.3179632 0.4944930 0.3179632 0.5590023 457s [148] 0.3179632 0.5551694 0.5551694 0.5940988 0.4944930 0.5551694 0.5940988 457s [155] 0.4944930 0.5940988 0.5590023 0.5590023 0.3179632 0.5551694 0.3179632 457s [162] 0.3179632 0.5940988 0.5940988 0.3179632 0.3179632 0.3179632 0.3179632 457s [169] 0.5940988 0.5590023 0.5551694 0.4944930 0.3179632 0.5590023 0.3179632 457s [176] 0.4944930 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 457s [183] 0.5940988 0.4944930 0.5551694 0.3179632 0.3179632 0.3179632 0.5940988 457s [190] 0.4944930 0.3179632 0.4944930 0.5940988 0.4944930 0.3179632 0.3179632 457s [197] 0.3179632 0.5551694 0.5590023 0.5940988 0.3179632 0.5940988 0.3179632 457s [204] 0.5551694 0.3179632 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 457s [211] 0.5940988 0.3179632 0.4944930 0.4944930 0.5940988 0.5551694 0.4944930 457s [218] 0.3179632 0.3179632 0.5551694 0.4944930 0.3179632 0.3179632 0.5551694 457s [225] 0.4944930 0.5590023 0.3179632 0.5940988 0.3179632 0.5551694 0.3179632 457s [232] 0.3179632 0.4944930 0.5551694 0.3179632 0.3179632 0.4944930 0.5551694 457s [239] 0.4944930 0.4944930 0.3179632 0.4944930 0.5551694 0.5940988 0.3179632 457s [246] 0.4944930 0.3179632 0.3179632 0.4944930 0.5940988 0.5551694 0.5551694 457s [253] 0.5590023 0.5940988 0.3179632 0.5940988 0.4944930 0.5551694 0.3179632 457s [260] 0.3179632 0.3179632 0.3179632 0.5590023 0.5551694 0.5551694 0.5551694 457s [267] 0.5551694 0.5551694 0.5551694 0.3179632 0.4944930 0.4944930 0.5940988 457s [274] 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 0.4944930 457s [281] 0.3179632 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 457s [288] 0.5590023 0.5551694 0.3179632 0.3179632 0.5551694 0.5940988 0.3179632 457s [295] 0.5551694 0.5551694 0.4944930 0.5551694 0.3179632 0.4944930 0.3179632 457s [302] 0.3179632 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 457s [309] 0.5590023 0.5940988 0.5940988 0.5551694 0.4944930 0.5551694 0.3179632 457s [316] 0.5940988 0.4944930 0.5551694 0.4944930 0.5590023 0.3179632 0.5551694 457s [323] 0.3179632 0.3179632 0.5551694 0.4944930 0.4944930 0.4944930 0.4944930 457s [330] 0.5590023 0.5940988 0.5551694 0.3179632 0.5551694 0.3179632 0.4944930 457s [337] 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.3179632 457s [344] 0.5940988 0.4944930 0.4944930 0.5940988 0.5590023 0.5940988 0.3179632 457s [351] 0.3179632 0.3179632 0.4944930 457s 457s [1] 50.13645 457s [1] 2052.27 457s [1] 2052.27 457s Dose Response Model 457s 457s Model: sigEmax 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -13.6642 -2.5494 -0.0589 3.1494 10.8255 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -9.3604 8.43e-01 457s eMax 18.0312 4.04e+00 457s ed50 427.8168 1.83e+02 457s h 1.3276 3.36e-01 457s age -0.0117 8.11e-03 457s centergreen -0.7488 7.57e-01 457s centerred -0.8859 7.12e-01 457s centersilver -1.4084 7.52e-01 457s centeryellow -1.4438 7.33e-01 457s 457s Residual standard error: 4.36 457s Degrees of freedom: 344 457s 457s Formula: y ~ cbind(XX, sigEmax(x, 0, 1, ed50, h)) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s ed50 427.813485 182.738235 2.341 0.0198 * 457s h 1.327626 0.335875 3.953 9.38e-05 *** 457s .lin.(Intercept) -9.360422 0.842795 -11.106 < 2e-16 *** 457s .lin.centergreen -0.748766 0.757412 -0.989 0.3236 457s .lin.centerred -0.885871 0.711909 -1.244 0.2142 457s .lin.centersilver -1.408359 0.752071 -1.873 0.0620 . 457s .lin.centeryellow -1.443811 0.733469 -1.968 0.0498 * 457s .lin.age -0.011703 0.008114 -1.442 0.1501 457s .lin7 18.031101 4.042408 4.460 1.11e-05 *** 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 4.36 on 344 degrees of freedom 457s 457s Number of iterations to convergence: 4 457s Achieved convergence tolerance: 7.011e-06 457s 457s e0 eMax ed50 h 457s e0 0.710302651 -4.248050e-01 12.9547646 5.611113e-02 457s eMax -0.424805031 1.634158e+01 694.3472381 -1.241172e+00 457s ed50 12.954764636 6.943472e+02 33394.5385877 -4.820462e+01 457s h 0.056111134 -1.241172e+00 -48.2046174 1.128111e-01 457s age -0.003282055 -7.347999e-04 -0.0251683 3.613375e-05 457s centergreen -0.239527553 2.751352e-02 1.4126289 -4.650674e-03 457s centerred -0.290825609 -1.412230e-01 -9.3345325 5.133219e-03 457s centersilver -0.296694203 -2.684223e-01 -15.5401130 1.239080e-02 457s centeryellow -0.294618448 -1.827692e-01 -11.6914478 8.045886e-03 457s age centergreen centerred centersilver 457s e0 -3.282055e-03 -0.2395275534 -2.908256e-01 -2.966942e-01 457s eMax -7.347999e-04 0.0275135152 -1.412230e-01 -2.684223e-01 457s ed50 -2.516830e-02 1.4126288554 -9.334532e+00 -1.554011e+01 457s h 3.613375e-05 -0.0046506738 5.133219e-03 1.239080e-02 457s age 6.584109e-05 -0.0004705249 3.847994e-05 1.268608e-04 457s centergreen -4.705249e-04 0.5736725480 2.674552e-01 2.669211e-01 457s centerred 3.847994e-05 0.2674552437 5.068148e-01 2.741110e-01 457s centersilver 1.268608e-04 0.2669210775 2.741110e-01 5.656114e-01 457s centeryellow 3.360823e-05 0.2672881708 2.729000e-01 2.753064e-01 457s centeryellow 457s e0 -2.946184e-01 457s eMax -1.827692e-01 457s ed50 -1.169145e+01 457s h 8.045886e-03 457s age 3.360823e-05 457s centergreen 2.672882e-01 457s centerred 2.729000e-01 457s centersilver 2.753064e-01 457s centeryellow 5.379774e-01 457s ed50 h .lin.(Intercept) .lin.centergreen 457s ed50 3.339326e+04 -4.820368e+01 12.954857951 1.4125968763 457s h -4.820368e+01 1.128119e-01 0.056111301 -0.0046506977 457s .lin.(Intercept) 1.295486e+01 5.611130e-02 0.710302646 -0.2395275479 457s .lin.centergreen 1.412597e+00 -4.650698e-03 -0.239527548 0.5736725490 457s .lin.centerred -9.334399e+00 5.133265e-03 -0.290825609 0.2674552401 457s .lin.centersilver -1.553987e+01 1.239088e-02 -0.296694200 0.2669210719 457s .lin.centeryellow -1.169127e+01 8.045945e-03 -0.294618447 0.2672881664 457s .lin.age -2.516783e-02 3.613396e-05 -0.003282055 -0.0004705249 457s .lin7 6.943216e+02 -1.241157e+00 -0.424801883 0.0275130191 457s .lin.centerred .lin.centersilver .lin.centeryellow 457s ed50 -9.334399e+00 -1.553987e+01 -1.169127e+01 457s h 5.133265e-03 1.239088e-02 8.045945e-03 457s .lin.(Intercept) -2.908256e-01 -2.966942e-01 -2.946184e-01 457s .lin.centergreen 2.674552e-01 2.669211e-01 2.672882e-01 457s .lin.centerred 5.068148e-01 2.741110e-01 2.729000e-01 457s .lin.centersilver 2.741110e-01 5.656114e-01 2.753064e-01 457s .lin.centeryellow 2.729000e-01 2.753064e-01 5.379774e-01 457s .lin.age 3.847993e-05 1.268608e-04 3.360822e-05 457s .lin7 -1.412207e-01 -2.684181e-01 -1.827663e-01 457s .lin.age .lin7 457s ed50 -2.516783e-02 6.943216e+02 457s h 3.613396e-05 -1.241157e+00 457s .lin.(Intercept) -3.282055e-03 -4.248019e-01 457s .lin.centergreen -4.705249e-04 2.751302e-02 457s .lin.centerred 3.847993e-05 -1.412207e-01 457s .lin.centersilver 1.268608e-04 -2.684181e-01 457s .lin.centeryellow 3.360822e-05 -1.827663e-01 457s .lin.age 6.584109e-05 -7.347909e-04 457s .lin7 -7.347909e-04 1.634107e+01 457s $fit 457s [1] 0.000000 2.286007 457s 457s $se.fit 457s [1] 0.0000000 0.7638951 457s 457s $fit 457s [1] -11.353936 -9.067928 457s 457s $se.fit 457s [1] 0.7291152 0.7547668 457s 457s [1] 50.56495 457s [1] 336.0966 457s [1] 336.0966 457s Dose Response Model 457s 457s Model: logistic 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -6.606 -1.402 -0.298 1.561 5.618 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -8.93 1.09 457s eMax 7.45 1.19 457s ed50 288.28 49.89 457s delta 43.71 37.57 457s 457s Residual standard error: 2.32 457s Degrees of freedom: 69 457s 457s Formula: y ~ logistic(x, e0, emax, ed50, delta) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s e0 -8.931 1.092 -8.179 9.42e-12 *** 457s emax 7.453 1.192 6.251 2.94e-08 *** 457s ed50 288.282 49.890 5.778 1.99e-07 *** 457s delta 43.709 37.566 1.164 0.249 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 2.323 on 69 degrees of freedom 457s 457s Number of iterations to convergence: 5 457s Achieved convergence tolerance: 1.919e-07 457s 457s e0 eMax ed50 delta 457s e0 1.192360 -1.220565 45.77140 -33.34815 457s eMax -1.220565 1.421491 -43.96678 35.28563 457s ed50 45.771404 -43.966775 2488.99403 -1733.71521 457s delta -33.348145 35.285633 -1733.71521 1411.22511 457s e0 emax ed50 delta 457s e0 1.192360 -1.220566 45.77135 -33.34807 457s emax -1.220566 1.421491 -43.96672 35.28556 457s ed50 45.771350 -43.966716 2488.98722 -1733.70801 457s delta -33.348072 35.285560 -1733.70801 1411.21852 457s $fit 457s [1] 0.0000000 5.6020564 7.4419763 7.4430636 5.6020564 0.3578039 7.4430636 457s [8] 0.3578039 7.4130064 7.4419763 5.6020564 5.6020564 5.6020564 5.6020564 457s [15] 5.6020564 5.6020564 7.4130064 0.3578039 0.3578039 7.4419763 0.3578039 457s [22] 7.4430636 0.3578039 7.4419763 7.4430636 0.3578039 7.4419763 7.4419763 457s [29] 5.6020564 0.0000000 7.4419763 5.6020564 7.4130064 7.4130064 7.4430636 457s [36] 0.0000000 7.4419763 7.4430636 5.6020564 5.6020564 5.6020564 7.4419763 457s [43] 5.6020564 0.3578039 7.4130064 5.6020564 7.4419763 0.3578039 5.6020564 457s [50] 0.0000000 5.6020564 7.4130064 7.4430636 5.6020564 0.3578039 7.4419763 457s [57] 7.4130064 7.4430636 7.4419763 7.4430636 0.0000000 5.6020564 5.6020564 457s [64] 5.6020564 7.4419763 5.6020564 7.4419763 7.4130064 7.4419763 5.6020564 457s [71] 5.6020564 0.3578039 5.6020564 457s 457s $se.fit 457s [1] 0.000000 1.134891 1.131632 1.137062 1.134891 1.244804 1.137062 1.244804 457s [9] 1.051179 1.131632 1.134891 1.134891 1.134891 1.134891 1.134891 1.134891 457s [17] 1.051179 1.244804 1.244804 1.131632 1.244804 1.137062 1.244804 1.131632 457s [25] 1.137062 1.244804 1.131632 1.131632 1.134891 0.000000 1.131632 1.134891 457s [33] 1.051179 1.051179 1.137062 0.000000 1.131632 1.137062 1.134891 1.134891 457s [41] 1.134891 1.131632 1.134891 1.244804 1.051179 1.134891 1.131632 1.244804 457s [49] 1.134891 0.000000 1.134891 1.051179 1.137062 1.134891 1.244804 1.131632 457s [57] 1.051179 1.137062 1.131632 1.137062 0.000000 1.134891 1.134891 1.134891 457s [65] 1.131632 1.134891 1.131632 1.051179 1.131632 1.134891 1.134891 1.244804 457s [73] 1.134891 457s 457s $fit 457s [1] -8.920547 -3.318491 -1.478571 -1.477483 -3.318491 -8.562743 -1.477483 457s [8] -8.562743 -1.507541 -1.478571 -3.318491 -3.318491 -3.318491 -3.318491 457s [15] -3.318491 -3.318491 -1.507541 -8.562743 -8.562743 -1.478571 -8.562743 457s [22] -1.477483 -8.562743 -1.478571 -1.477483 -8.562743 -1.478571 -1.478571 457s [29] -3.318491 -8.920547 -1.478571 -3.318491 -1.507541 -1.507541 -1.477483 457s [36] -8.920547 -1.478571 -1.477483 -3.318491 -3.318491 -3.318491 -1.478571 457s [43] -3.318491 -8.562743 -1.507541 -3.318491 -1.478571 -8.562743 -3.318491 457s [50] -8.920547 -3.318491 -1.507541 -1.477483 -3.318491 -8.562743 -1.478571 457s [57] -1.507541 -1.477483 -1.478571 -1.477483 -8.920547 -3.318491 -3.318491 457s [64] -3.318491 -1.478571 -3.318491 -1.478571 -1.507541 -1.478571 -3.318491 457s [71] -3.318491 -8.562743 -3.318491 457s 457s $se.fit 457s [1] 1.0345960 0.4644528 0.4144011 0.4155112 0.4644528 0.6986843 0.4155112 457s [8] 0.6986843 0.4088615 0.4144011 0.4644528 0.4644528 0.4644528 0.4644528 457s [15] 0.4644528 0.4644528 0.4088615 0.6986843 0.6986843 0.4144011 0.6986843 457s [22] 0.4155112 0.6986843 0.4144011 0.4155112 0.6986843 0.4144011 0.4144011 457s [29] 0.4644528 1.0345960 0.4144011 0.4644528 0.4088615 0.4088615 0.4155112 457s [36] 1.0345960 0.4144011 0.4155112 0.4644528 0.4644528 0.4644528 0.4144011 457s [43] 0.4644528 0.6986843 0.4088615 0.4644528 0.4144011 0.6986843 0.4644528 457s [50] 1.0345960 0.4644528 0.4088615 0.4155112 0.4644528 0.6986843 0.4144011 457s [57] 0.4088615 0.4155112 0.4144011 0.4155112 1.0345960 0.4644528 0.4644528 457s [64] 0.4644528 0.4144011 0.4644528 0.4144011 0.4088615 0.4144011 0.4644528 457s [71] 0.4644528 0.6986843 0.4644528 457s 457s [1] 174.1673 457s [1] 345.1575 457s [1] 345.1575 457s Dose Response Model 457s 457s Model: logistic 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -6.924 -1.388 -0.179 1.618 5.265 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -8.98657 1.419 457s eMax 7.65181 1.269 457s ed50 286.51988 50.767 457s delta 43.51040 36.726 457s age -0.00402 0.011 457s centergreen -0.12880 0.873 457s centerred 0.10022 0.975 457s centersilver 0.60689 0.985 457s centeryellow 0.06974 0.968 457s 457s Residual standard error: 2.4 457s Degrees of freedom: 64 457s 457s Formula: y ~ cbind(XX, logistic(x, 0, 1, ed50, delta)) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s ed50 286.519964 50.768015 5.644 4.08e-07 *** 457s delta 43.510063 36.726740 1.185 0.241 457s .lin.(Intercept) -8.986562 1.418992 -6.333 2.71e-08 *** 457s .lin.centergreen -0.128797 0.873355 -0.147 0.883 457s .lin.centerred 0.100221 0.975122 0.103 0.918 457s .lin.centersilver 0.606894 0.985016 0.616 0.540 457s .lin.centeryellow 0.069737 0.968243 0.072 0.943 457s .lin.age -0.004017 0.011024 -0.364 0.717 457s .lin7 7.651799 1.268713 6.031 8.96e-08 *** 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 2.396 on 64 degrees of freedom 457s 457s Number of iterations to convergence: 4 457s Achieved convergence tolerance: 6.662e-06 457s 457s e0 eMax ed50 delta 457s e0 2.013542598 -1.386381624 4.801326e+01 -3.320465e+01 457s eMax -1.386381624 1.609637809 -4.594280e+01 3.537786e+01 457s ed50 48.013263927 -45.942796989 2.577339e+03 -1.719550e+03 457s delta -33.204646040 35.377861787 -1.719550e+03 1.348832e+03 457s age -0.006268645 0.001147196 1.238916e-02 -1.182615e-04 457s centergreen -0.334052153 -0.153718220 1.779756e+00 -1.607538e+00 457s centerred -0.399667176 -0.068891593 -2.561521e+00 7.131922e-01 457s centersilver -0.538856175 0.113916607 8.446386e-02 -1.524166e+00 457s centeryellow -0.463856043 -0.044371048 -3.153773e+00 1.284203e+00 457s age centergreen centerred centersilver 457s e0 -0.0062686454 -0.3340521534 -0.399667176 -0.5388561747 457s eMax 0.0011471962 -0.1537182198 -0.068891593 0.1139166068 457s ed50 0.0123891577 1.7797560821 -2.561520564 0.0844638637 457s delta -0.0001182615 -1.6075377841 0.713192229 -1.5241663474 457s age 0.0001215321 -0.0007558322 -0.001348561 -0.0006628626 457s centergreen -0.0007558322 0.7627491953 0.499187248 0.4609636575 457s centerred -0.0013485609 0.4991872483 0.950863865 0.4738663247 457s centersilver -0.0006628626 0.4609636575 0.473866325 0.9702565708 457s centeryellow -0.0003700776 0.4923423826 0.498378928 0.4677967285 457s centeryellow 457s e0 -0.4638560434 457s eMax -0.0443710477 457s ed50 -3.1537729813 457s delta 1.2842028647 457s age -0.0003700776 457s centergreen 0.4923423826 457s centerred 0.4983789279 457s centersilver 0.4677967285 457s centeryellow 0.9374951281 457s ed50 delta .lin.(Intercept) .lin.centergreen 457s ed50 2.577391e+03 -1.719586e+03 48.013677315 1.7797792567 457s delta -1.719586e+03 1.348853e+03 -33.204888391 -1.6075530130 457s .lin.(Intercept) 4.801368e+01 -3.320489e+01 2.013538898 -0.3340522698 457s .lin.centergreen 1.779779e+00 -1.607553e+00 -0.334052270 0.7627491914 457s .lin.centerred -2.561536e+00 7.132043e-01 -0.399667186 0.4991872438 457s .lin.centersilver 8.448346e-02 -1.524166e+00 -0.538856201 0.4609636569 457s .lin.centeryellow -3.153788e+00 1.284211e+00 -0.463855836 0.4923423906 457s .lin.age 1.238908e-02 -1.181843e-04 -0.006268647 -0.0007558323 457s .lin7 -4.594321e+01 3.537808e+01 -1.386377238 -0.1537180607 457s .lin.centerred .lin.centersilver .lin.centeryellow 457s ed50 -2.561536182 0.0844834632 -3.1537877329 457s delta 0.713204316 -1.5241655404 1.2842105849 457s .lin.(Intercept) -0.399667186 -0.5388562012 -0.4638558362 457s .lin.centergreen 0.499187244 0.4609636569 0.4923423906 457s .lin.centerred 0.950863862 0.4738663194 0.4983789309 457s .lin.centersilver 0.473866319 0.9702565797 0.4677967416 457s .lin.centeryellow 0.498378931 0.4677967416 0.9374951276 457s .lin.age -0.001348561 -0.0006628628 -0.0003700776 457s .lin7 -0.068891565 0.1139166786 -0.0443712888 457s .lin.age .lin7 457s ed50 0.0123890830 -45.943205630 457s delta -0.0001181843 35.378080025 457s .lin.(Intercept) -0.0062686472 -1.386377238 457s .lin.centergreen -0.0007558323 -0.153718061 457s .lin.centerred -0.0013485609 -0.068891565 457s .lin.centersilver -0.0006628628 0.113916679 457s .lin.centeryellow -0.0003700776 -0.044371289 457s .lin.age 0.0001215321 0.001147198 457s .lin7 0.0011471983 1.609632528 457s $fit 457s [1] 0.00000000 0.09322688 457s 457s $se.fit 457s [1] 0.0000000 0.4246053 457s 457s $fit 457s [1] -8.389208 -8.295981 457s 457s $se.fit 457s [1] 1.306647 1.060317 457s 457s [1] 46.37307 457s [1] -1501.193 457s [1] -1501.193 457s Dose Response Model 457s 457s Model: exponential 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -2.70e-01 -5.95e-02 7.18e-05 5.87e-02 2.44e-01 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -0.466 6.03e-03 457s e1 0.125 9.54e-02 457s delta 972.943 4.86e+02 457s 457s Residual standard error: 0.0841 457s Degrees of freedom: 710 457s 457s Formula: y ~ exponential(x, e0, e1, delta) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s e0 -0.466094 0.006025 -77.359 <2e-16 *** 457s e1 0.124504 0.095374 1.305 0.1922 457s delta 972.943061 485.901662 2.002 0.0456 * 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 0.08415 on 710 degrees of freedom 457s 457s Number of iterations to convergence: 0 457s Achieved convergence tolerance: 1.033e-08 457s 457s e0 e1 delta 457s e0 3.630153e-05 -0.0004207858 -2.060285 457s e1 -4.207858e-04 0.0090961407 46.252646 457s delta -2.060285e+00 46.2526456895 236100.427432 457s e0 e1 delta 457s e0 3.630155e-05 -0.000420786 -2.060286 457s e1 -4.207860e-04 0.009096141 46.252645 457s delta -2.060286e+00 46.252645043 236100.424914 457s $fit 457s [1] 0.00000000 0.03271671 0.00000000 0.11169230 0.01605388 0.18278309 457s [7] 0.18278309 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 457s [13] 0.11169230 0.01605388 0.18278309 0.18278309 0.18278309 0.18278309 457s [19] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.00000000 457s [25] 0.01605388 0.00000000 0.11169230 0.00000000 0.18278309 0.03271671 457s [31] 0.18278309 0.01605388 0.00000000 0.03271671 0.00000000 0.03271671 457s [37] 0.03271671 0.11169230 0.00000000 0.03271671 0.01605388 0.18278309 457s [43] 0.01605388 0.03271671 0.01605388 0.01605388 0.01605388 0.18278309 457s [49] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 457s [55] 0.03271671 0.03271671 0.01605388 0.00000000 0.11169230 0.18278309 457s [61] 0.00000000 0.18278309 0.18278309 0.03271671 0.03271671 0.01605388 457s [67] 0.00000000 0.03271671 0.18278309 0.01605388 0.03271671 0.00000000 457s [73] 0.00000000 0.01605388 0.18278309 0.01605388 0.00000000 0.01605388 457s [79] 0.01605388 0.01605388 0.18278309 0.18278309 0.00000000 0.01605388 457s [85] 0.11169230 0.11169230 0.01605388 0.18278309 0.11169230 0.03271671 457s [91] 0.03271671 0.18278309 0.01605388 0.11169230 0.03271671 0.00000000 457s [97] 0.18278309 0.00000000 0.00000000 0.01605388 0.11169230 0.00000000 457s [103] 0.11169230 0.03271671 0.11169230 0.18278309 0.01605388 0.00000000 457s [109] 0.11169230 0.01605388 0.11169230 0.00000000 0.00000000 0.01605388 457s [115] 0.11169230 0.01605388 0.11169230 0.11169230 0.18278309 0.01605388 457s [121] 0.11169230 0.18278309 0.00000000 0.03271671 0.18278309 0.01605388 457s [127] 0.01605388 0.03271671 0.03271671 0.11169230 0.11169230 0.18278309 457s [133] 0.00000000 0.00000000 0.01605388 0.01605388 0.01605388 0.01605388 457s [139] 0.01605388 0.18278309 0.18278309 0.01605388 0.00000000 0.18278309 457s [145] 0.00000000 0.01605388 0.18278309 0.03271671 0.18278309 0.01605388 457s [151] 0.00000000 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 457s [157] 0.01605388 0.01605388 0.00000000 0.11169230 0.00000000 0.00000000 457s [163] 0.01605388 0.03271671 0.03271671 0.00000000 0.11169230 0.18278309 457s [169] 0.18278309 0.01605388 0.03271671 0.03271671 0.11169230 0.01605388 457s [175] 0.01605388 0.03271671 0.03271671 0.00000000 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0.007313632 457s [7] 0.007313632 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 457s [13] 0.006884091 0.003835233 0.007313632 0.007313632 0.007313632 0.007313632 457s [19] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.006025075 457s [25] 0.003835233 0.006025075 0.006884091 0.006025075 0.007313632 0.004212735 457s [31] 0.007313632 0.003835233 0.006025075 0.004212735 0.006025075 0.004212735 457s [37] 0.004212735 0.006884091 0.006025075 0.004212735 0.003835233 0.007313632 457s [43] 0.003835233 0.004212735 0.003835233 0.003835233 0.003835233 0.007313632 457s [49] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 457s [55] 0.004212735 0.004212735 0.003835233 0.006025075 0.006884091 0.007313632 457s [61] 0.006025075 0.007313632 0.007313632 0.004212735 0.004212735 0.003835233 457s [67] 0.006025075 0.004212735 0.007313632 0.003835233 0.004212735 0.006025075 457s [73] 0.006025075 0.003835233 0.007313632 0.003835233 0.006025075 0.003835233 457s 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0.006025075 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 457s [157] 0.003835233 0.003835233 0.006025075 0.006884091 0.006025075 0.006025075 457s [163] 0.003835233 0.004212735 0.004212735 0.006025075 0.006884091 0.007313632 457s [169] 0.007313632 0.003835233 0.004212735 0.004212735 0.006884091 0.003835233 457s [175] 0.003835233 0.004212735 0.004212735 0.006025075 0.003835233 0.003835233 457s [181] 0.006884091 0.003835233 0.004212735 0.007313632 0.006884091 0.003835233 457s [187] 0.006884091 0.004212735 0.003835233 0.004212735 0.006025075 0.007313632 457s [193] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.006884091 457s [199] 0.003835233 0.006025075 0.006884091 0.006884091 0.003835233 0.004212735 457s [205] 0.006025075 0.003835233 0.006025075 0.006025075 0.003835233 0.003835233 457s [211] 0.003835233 0.004212735 0.003835233 0.004212735 0.003835233 0.007313632 457s [217] 0.003835233 0.006884091 0.003835233 0.007313632 0.006884091 0.003835233 457s [223] 0.006884091 0.007313632 0.004212735 0.007313632 0.004212735 0.006884091 457s [229] 0.006884091 0.006025075 0.003835233 0.003835233 0.006884091 0.006025075 457s [235] 0.007313632 0.004212735 0.003835233 0.006884091 0.007313632 0.007313632 457s [241] 0.003835233 0.004212735 0.006025075 0.004212735 0.007313632 0.003835233 457s [247] 0.003835233 0.004212735 0.003835233 0.006884091 0.004212735 0.004212735 457s [253] 0.006884091 0.006025075 0.006025075 0.006025075 0.003835233 0.006884091 457s [259] 0.007313632 0.003835233 0.007313632 0.003835233 0.007313632 0.004212735 457s [265] 0.003835233 0.004212735 0.003835233 0.007313632 0.007313632 0.004212735 457s [271] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.003835233 457s [277] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.004212735 457s [283] 0.007313632 0.003835233 0.006025075 0.003835233 0.003835233 0.003835233 457s [289] 0.006884091 0.004212735 0.004212735 0.003835233 0.004212735 0.003835233 457s [295] 0.004212735 0.006025075 0.006025075 0.003835233 0.006025075 0.003835233 457s [301] 0.006884091 0.006884091 0.007313632 0.006884091 0.003835233 0.003835233 457s [307] 0.003835233 0.004212735 0.004212735 0.004212735 0.003835233 0.007313632 457s [313] 0.004212735 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 457s [319] 0.004212735 0.006884091 0.004212735 0.003835233 0.003835233 0.003835233 457s [325] 0.007313632 0.006884091 0.003835233 0.004212735 0.007313632 0.003835233 457s [331] 0.006884091 0.004212735 0.003835233 0.004212735 0.004212735 0.003835233 457s [337] 0.003835233 0.006884091 0.003835233 0.004212735 0.003835233 0.003835233 457s [343] 0.006025075 0.003835233 0.004212735 0.003835233 0.006884091 0.007313632 457s [349] 0.003835233 0.003835233 0.003835233 0.007313632 0.006884091 0.004212735 457s [355] 0.007313632 0.003835233 0.006884091 0.004212735 0.004212735 0.003835233 457s [361] 0.003835233 0.003835233 0.003835233 0.006025075 0.004212735 0.007313632 457s [367] 0.004212735 0.007313632 0.007313632 0.003835233 0.003835233 0.006884091 457s [373] 0.003835233 0.006884091 0.003835233 0.007313632 0.007313632 0.003835233 457s [379] 0.007313632 0.007313632 0.006884091 0.006884091 0.007313632 0.004212735 457s [385] 0.007313632 0.004212735 0.007313632 0.003835233 0.006884091 0.006025075 457s [391] 0.003835233 0.006025075 0.006025075 0.003835233 0.003835233 0.004212735 457s [397] 0.004212735 0.004212735 0.006025075 0.006025075 0.003835233 0.006025075 457s [403] 0.006884091 0.004212735 0.004212735 0.006025075 0.004212735 0.003835233 457s [409] 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 0.006884091 457s [415] 0.003835233 0.006884091 0.007313632 0.006884091 0.003835233 0.004212735 457s [421] 0.003835233 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 457s [427] 0.004212735 0.006025075 0.007313632 0.003835233 0.006884091 0.003835233 457s [433] 0.003835233 0.003835233 0.006025075 0.003835233 0.006884091 0.006025075 457s [439] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 457s [445] 0.006025075 0.006025075 0.003835233 0.003835233 0.006025075 0.004212735 457s [451] 0.007313632 0.003835233 0.006884091 0.006025075 0.003835233 0.006025075 457s [457] 0.003835233 0.006025075 0.007313632 0.003835233 0.003835233 0.006884091 457s [463] 0.003835233 0.004212735 0.007313632 0.007313632 0.006884091 0.007313632 457s [469] 0.003835233 0.003835233 0.006025075 0.003835233 0.003835233 0.004212735 457s [475] 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 457s [481] 0.006025075 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 457s [487] 0.007313632 0.006884091 0.007313632 0.003835233 0.006884091 0.007313632 457s [493] 0.006884091 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 457s [499] 0.004212735 0.003835233 0.007313632 0.006884091 0.007313632 0.007313632 457s [505] 0.003835233 0.006025075 0.003835233 0.007313632 0.007313632 0.003835233 457s [511] 0.004212735 0.003835233 0.007313632 0.003835233 0.003835233 0.004212735 457s [517] 0.003835233 0.003835233 0.004212735 0.006025075 0.004212735 0.004212735 457s [523] 0.007313632 0.004212735 0.004212735 0.004212735 0.004212735 0.006025075 457s [529] 0.003835233 0.007313632 0.004212735 0.006884091 0.007313632 0.003835233 457s [535] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.006025075 457s [541] 0.004212735 0.006884091 0.004212735 0.007313632 0.004212735 0.003835233 457s [547] 0.004212735 0.006025075 0.006025075 0.007313632 0.004212735 0.006884091 457s [553] 0.006884091 0.003835233 0.006025075 0.004212735 0.006025075 0.003835233 457s [559] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.004212735 457s [565] 0.004212735 0.003835233 0.006884091 0.006884091 0.004212735 0.003835233 457s [571] 0.006884091 0.006025075 0.006025075 0.003835233 0.006025075 0.003835233 457s [577] 0.004212735 0.004212735 0.006025075 0.003835233 0.003835233 0.006884091 457s [583] 0.004212735 0.007313632 0.003835233 0.006884091 0.007313632 0.003835233 457s [589] 0.003835233 0.003835233 0.007313632 0.003835233 0.007313632 0.003835233 457s [595] 0.007313632 0.007313632 0.006884091 0.004212735 0.004212735 0.003835233 457s [601] 0.003835233 0.003835233 0.007313632 0.004212735 0.004212735 0.003835233 457s [607] 0.003835233 0.007313632 0.007313632 0.006884091 0.004212735 0.007313632 457s [613] 0.007313632 0.003835233 0.003835233 0.006025075 0.007313632 0.003835233 457s [619] 0.006884091 0.003835233 0.006884091 0.006025075 0.003835233 0.003835233 457s [625] 0.007313632 0.003835233 0.004212735 0.004212735 0.006025075 0.006025075 457s [631] 0.006025075 0.006025075 0.006025075 0.003835233 0.007313632 0.004212735 457s [637] 0.006025075 0.003835233 0.006884091 0.007313632 0.003835233 0.006884091 457s [643] 0.003835233 0.006025075 0.003835233 0.004212735 0.004212735 0.003835233 457s [649] 0.006025075 0.003835233 0.006884091 0.006884091 0.007313632 0.007313632 457s [655] 0.006884091 0.003835233 0.004212735 0.004212735 0.003835233 0.003835233 457s [661] 0.006025075 0.003835233 0.004212735 0.006884091 0.003835233 0.003835233 457s [667] 0.003835233 0.003835233 0.003835233 0.003835233 0.006025075 0.003835233 457s [673] 0.004212735 0.007313632 0.003835233 0.003835233 0.007313632 0.006025075 457s [679] 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 457s [685] 0.007313632 0.007313632 0.006884091 0.004212735 0.006025075 0.004212735 457s [691] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.003835233 457s [697] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 457s [703] 0.006884091 0.006884091 0.003835233 0.003835233 0.003835233 0.003835233 457s [709] 0.004212735 0.006884091 0.003835233 0.007313632 0.003835233 457s 457s [1] 573.604 457s [1] -1502.21 457s [1] -1502.21 457s Dose Response Model 457s 457s Model: exponential 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -2.72e-01 -5.96e-02 -5.44e-06 5.59e-02 2.43e-01 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -4.57e-01 1.03e-02 457s e1 1.24e-01 9.45e-02 457s delta 9.69e+02 4.79e+02 457s age -2.46e-04 1.09e-04 457s centergreen -2.26e-03 9.93e-03 457s centerred 7.10e-03 9.88e-03 457s centersilver 1.68e-02 1.02e-02 457s centeryellow -4.45e-03 1.01e-02 457s 457s Residual standard error: 0.0838 457s Degrees of freedom: 705 457s 457s Formula: y ~ cbind(XX, exponential(x, 0, 1, delta)) 457s 457s Parameters: 457s Estimate Std. Error t value Pr(>|t|) 457s delta 9.692e+02 4.795e+02 2.021 0.0436 * 457s .lin.(Intercept) -4.574e-01 1.035e-02 -44.200 <2e-16 *** 457s .lin.centergreen -2.256e-03 9.934e-03 -0.227 0.8204 457s .lin.centerred 7.104e-03 9.875e-03 0.719 0.4721 457s .lin.centersilver 1.682e-02 1.018e-02 1.652 0.0989 . 457s .lin.centeryellow -4.446e-03 1.005e-02 -0.442 0.6584 457s .lin.age -2.463e-04 1.090e-04 -2.259 0.0242 * 457s .lin7 1.244e-01 9.455e-02 1.316 0.1886 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 0.0838 on 705 degrees of freedom 457s 457s Number of iterations to convergence: 7 457s Achieved convergence tolerance: 8.746e-06 457s 457s e0 e1 delta age 457s e0 1.070950e-04 -3.644583e-04 -1.760351e+00 -6.235809e-07 457s e1 -3.644583e-04 8.939482e-03 4.524833e+01 -1.892275e-07 457s delta -1.760351e+00 4.524833e+01 2.299190e+05 -9.417514e-04 457s age -6.235809e-07 -1.892275e-07 -9.417514e-04 1.188604e-08 457s centergreen -4.990019e-05 -7.223387e-05 -3.668152e-01 4.308966e-08 457s centerred -5.090480e-05 -5.257812e-05 -2.765207e-01 2.992730e-08 457s centersilver -5.269569e-05 -5.104404e-05 -2.725146e-01 5.557593e-08 457s centeryellow -5.416568e-05 -3.395837e-05 -1.820278e-01 7.695026e-08 457s centergreen centerred centersilver centeryellow 457s e0 -4.990019e-05 -5.090480e-05 -5.269569e-05 -5.416568e-05 457s e1 -7.223387e-05 -5.257812e-05 -5.104404e-05 -3.395837e-05 457s delta -3.668152e-01 -2.765207e-01 -2.725146e-01 -1.820278e-01 457s age 4.308966e-08 2.992730e-08 5.557593e-08 7.695026e-08 457s centergreen 9.869293e-05 5.105736e-05 5.114013e-05 5.107251e-05 457s centerred 5.105736e-05 9.752101e-05 5.111632e-05 5.102188e-05 457s centersilver 5.114013e-05 5.111632e-05 1.036881e-04 5.122455e-05 457s centeryellow 5.107251e-05 5.102188e-05 5.122455e-05 1.010538e-04 457s delta .lin.(Intercept) .lin.centergreen 457s delta 2.299104e+05 -1.760315e+00 -3.668085e-01 457s .lin.(Intercept) -1.760315e+00 1.070949e-04 -4.990020e-05 457s .lin.centergreen -3.668085e-01 -4.990020e-05 9.869293e-05 457s .lin.centerred -2.765154e-01 -5.090480e-05 5.105736e-05 457s .lin.centersilver -2.725097e-01 -5.269570e-05 5.114013e-05 457s .lin.centeryellow -1.820244e-01 -5.416569e-05 5.107251e-05 457s .lin.age -9.417341e-04 -6.235810e-07 4.308966e-08 457s .lin7 4.524658e+01 -3.644504e-04 -7.223243e-05 457s .lin.centerred .lin.centersilver .lin.centeryellow 457s delta -2.765154e-01 -2.725097e-01 -1.820244e-01 457s .lin.(Intercept) -5.090480e-05 -5.269570e-05 -5.416569e-05 457s .lin.centergreen 5.105736e-05 5.114013e-05 5.107251e-05 457s .lin.centerred 9.752101e-05 5.111632e-05 5.102188e-05 457s .lin.centersilver 5.111632e-05 1.036881e-04 5.122455e-05 457s .lin.centeryellow 5.102188e-05 5.122455e-05 1.010538e-04 457s .lin.age 2.992730e-08 5.557593e-08 7.695026e-08 457s .lin7 -5.257703e-05 -5.104303e-05 -3.395767e-05 457s .lin.age .lin7 457s delta -9.417341e-04 4.524658e+01 457s .lin.(Intercept) -6.235810e-07 -3.644504e-04 457s .lin.centergreen 4.308966e-08 -7.223243e-05 457s .lin.centerred 2.992730e-08 -5.257703e-05 457s .lin.centersilver 5.557593e-08 -5.104303e-05 457s .lin.centeryellow 7.695026e-08 -3.395767e-05 457s .lin.age 1.188604e-08 -1.892238e-07 457s .lin7 -1.892238e-07 8.939124e-03 457s $fit 457s [1] 0.00000000 0.01352276 457s 457s $se.fit 457s [1] 0.000000000 0.003277925 457s 457s $fit 457s [1] -0.4697265 -0.4562037 457s 457s $se.fit 457s [1] 0.008628557 0.007549824 457s 457s [1] 571.7033 457s [1] 4189.744 457s [1] 4189.744 457s Dose Response Model 457s 457s Model: linear 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -20.3923 -4.1973 -0.0226 3.8448 25.3694 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -11.2122 0.393654 457s delta 0.0136 0.000531 457s 457s Residual standard error: 6.43 457s Degrees of freedom: 636 457s 457s Call: 457s lm(formula = y ~ x, data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -25.3694 -3.8448 0.0226 4.1973 20.3923 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -1.121e+01 3.937e-01 -28.48 <2e-16 *** 457s x 1.358e-02 5.313e-04 25.57 <2e-16 *** 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 6.433 on 636 degrees of freedom 457s Multiple R-squared: 0.5069, Adjusted R-squared: 0.5061 457s F-statistic: 653.7 on 1 and 636 DF, p-value: < 2.2e-16 457s 457s e0 delta 457s e0 0.1549638101 -1.594693e-04 457s delta -0.0001594693 2.822434e-07 457s (Intercept) x 457s (Intercept) 0.1549638101 -1.594693e-04 457s x -0.0001594693 2.822434e-07 457s $fit 457s [1] 3.382287 6.560821 12.605469 12.605469 17.251020 0.000000 0.000000 457s [8] 6.560821 17.251020 3.382287 15.892672 3.382287 0.000000 9.671438 457s [15] 15.892672 17.251020 12.605469 17.251020 3.382287 17.251020 17.251020 457s [22] 9.671438 3.382287 12.605469 0.000000 12.605469 3.382287 6.560821 457s [29] 0.000000 17.251020 0.000000 9.671438 12.605469 3.382287 3.382287 457s [36] 0.000000 0.000000 12.605469 0.000000 12.605469 0.000000 15.892672 457s [43] 12.605469 15.892672 3.382287 17.251020 17.251020 6.560821 3.382287 457s [50] 0.000000 9.671438 17.251020 15.892672 0.000000 3.382287 17.251020 457s [57] 6.560821 17.251020 0.000000 3.382287 12.605469 12.605469 0.000000 457s [64] 0.000000 15.892672 15.892672 0.000000 12.605469 15.892672 3.382287 457s [71] 15.892672 6.560821 3.382287 17.251020 12.605469 0.000000 12.605469 457s [78] 12.605469 3.382287 0.000000 0.000000 0.000000 3.382287 3.382287 457s [85] 3.382287 6.560821 3.382287 0.000000 3.382287 17.251020 6.560821 457s [92] 3.382287 17.251020 9.671438 3.382287 0.000000 3.382287 3.382287 457s [99] 12.605469 0.000000 3.382287 3.382287 12.605469 0.000000 0.000000 457s [106] 17.251020 0.000000 6.560821 15.892672 17.251020 3.382287 17.251020 457s [113] 3.382287 0.000000 0.000000 3.382287 6.560821 0.000000 6.560821 457s [120] 3.382287 0.000000 0.000000 6.560821 15.892672 12.605469 12.605469 457s [127] 0.000000 17.251020 0.000000 17.251020 3.382287 0.000000 12.605469 457s [134] 17.251020 0.000000 3.382287 0.000000 6.560821 6.560821 6.560821 457s [141] 3.382287 17.251020 0.000000 0.000000 3.382287 0.000000 15.892672 457s [148] 17.251020 3.382287 15.892672 0.000000 17.251020 6.560821 3.382287 457s [155] 12.605469 6.560821 6.560821 3.382287 3.382287 0.000000 3.382287 457s [162] 0.000000 3.382287 12.605469 3.382287 0.000000 17.251020 0.000000 457s [169] 0.000000 3.382287 17.251020 3.382287 17.251020 15.892672 6.560821 457s [176] 12.605469 3.382287 0.000000 12.605469 0.000000 12.605469 17.251020 457s [183] 12.605469 0.000000 0.000000 12.605469 3.382287 12.605469 17.251020 457s [190] 3.382287 3.382287 17.251020 3.382287 6.560821 3.382287 17.251020 457s [197] 17.251020 0.000000 12.605469 0.000000 12.605469 3.382287 6.560821 457s [204] 12.605469 12.605469 3.382287 3.382287 12.605469 17.251020 12.605469 457s [211] 3.382287 3.382287 17.251020 0.000000 6.560821 3.382287 3.382287 457s [218] 0.000000 6.560821 0.000000 6.560821 6.560821 3.382287 0.000000 457s [225] 3.382287 3.382287 17.251020 3.382287 0.000000 17.251020 3.382287 457s [232] 6.560821 17.251020 0.000000 0.000000 3.382287 3.382287 12.605469 457s [239] 6.560821 12.605469 3.382287 12.605469 17.251020 6.560821 17.251020 457s [246] 17.251020 15.892672 0.000000 3.382287 3.382287 3.382287 0.000000 457s [253] 12.605469 15.892672 6.560821 3.382287 3.382287 0.000000 0.000000 457s [260] 12.605469 6.560821 3.382287 3.382287 12.605469 17.251020 0.000000 457s [267] 6.560821 15.892672 3.382287 15.892672 3.382287 12.605469 0.000000 457s [274] 17.251020 15.892672 6.560821 3.382287 12.605469 0.000000 3.382287 457s [281] 3.382287 12.605469 3.382287 0.000000 17.251020 15.892672 17.251020 457s [288] 3.382287 17.251020 3.382287 3.382287 3.382287 15.892672 0.000000 457s [295] 0.000000 17.251020 17.251020 12.605469 0.000000 12.605469 17.251020 457s [302] 15.892672 15.892672 0.000000 3.382287 12.605469 12.605469 15.892672 457s [309] 6.560821 15.892672 12.605469 12.605469 17.251020 0.000000 17.251020 457s [316] 3.382287 17.251020 3.382287 12.605469 0.000000 6.560821 3.382287 457s [323] 0.000000 15.892672 17.251020 17.251020 17.251020 3.382287 6.560821 457s [330] 0.000000 0.000000 12.605469 12.605469 12.605469 0.000000 12.605469 457s [337] 0.000000 15.892672 6.560821 17.251020 12.605469 12.605469 6.560821 457s [344] 0.000000 0.000000 17.251020 0.000000 0.000000 12.605469 0.000000 457s [351] 3.382287 3.382287 6.560821 17.251020 9.671438 0.000000 9.671438 457s [358] 9.671438 12.605469 3.382287 12.605469 3.382287 17.251020 0.000000 457s [365] 12.605469 0.000000 3.382287 0.000000 3.382287 6.560821 0.000000 457s [372] 6.560821 6.560821 17.251020 15.892672 0.000000 17.251020 0.000000 457s [379] 3.382287 17.251020 3.382287 12.605469 3.382287 3.382287 12.605469 457s [386] 3.382287 3.382287 0.000000 15.892672 0.000000 12.605469 0.000000 457s [393] 15.892672 6.560821 15.892672 15.892672 6.560821 6.560821 3.382287 457s [400] 3.382287 17.251020 17.251020 6.560821 12.605469 9.671438 15.892672 457s [407] 17.251020 6.560821 3.382287 0.000000 6.560821 6.560821 15.892672 457s [414] 3.382287 0.000000 0.000000 0.000000 0.000000 3.382287 3.382287 457s [421] 0.000000 3.382287 3.382287 12.605469 17.251020 17.251020 17.251020 457s [428] 0.000000 15.892672 17.251020 17.251020 0.000000 0.000000 17.251020 457s [435] 12.605469 6.560821 0.000000 0.000000 3.382287 0.000000 15.892672 457s [442] 12.605469 17.251020 3.382287 12.605469 0.000000 17.251020 0.000000 457s [449] 6.560821 12.605469 6.560821 12.605469 15.892672 12.605469 12.605469 457s [456] 0.000000 0.000000 3.382287 0.000000 3.382287 0.000000 0.000000 457s [463] 0.000000 17.251020 6.560821 17.251020 12.605469 12.605469 3.382287 457s [470] 17.251020 0.000000 3.382287 0.000000 6.560821 0.000000 0.000000 457s [477] 3.382287 15.892672 3.382287 12.605469 0.000000 3.382287 12.605469 457s [484] 6.560821 17.251020 9.671438 15.892672 17.251020 15.892672 0.000000 457s [491] 0.000000 3.382287 3.382287 17.251020 0.000000 6.560821 12.605469 457s [498] 12.605469 12.605469 3.382287 3.382287 3.382287 15.892672 0.000000 457s [505] 6.560821 3.382287 17.251020 3.382287 12.605469 12.605469 15.892672 457s [512] 0.000000 12.605469 17.251020 6.560821 0.000000 3.382287 0.000000 457s [519] 15.892672 0.000000 12.605469 12.605469 0.000000 17.251020 0.000000 457s [526] 9.671438 0.000000 3.382287 15.892672 3.382287 3.382287 3.382287 457s [533] 17.251020 15.892672 0.000000 0.000000 0.000000 15.892672 6.560821 457s [540] 17.251020 17.251020 6.560821 0.000000 0.000000 3.382287 12.605469 457s [547] 12.605469 0.000000 3.382287 15.892672 0.000000 0.000000 3.382287 457s [554] 0.000000 0.000000 0.000000 17.251020 17.251020 17.251020 12.605469 457s [561] 0.000000 15.892672 0.000000 3.382287 3.382287 12.605469 6.560821 457s [568] 12.605469 3.382287 3.382287 0.000000 17.251020 6.560821 15.892672 457s [575] 0.000000 9.671438 3.382287 3.382287 0.000000 12.605469 3.382287 457s [582] 12.605469 3.382287 0.000000 6.560821 0.000000 3.382287 17.251020 457s [589] 3.382287 12.605469 12.605469 17.251020 3.382287 9.671438 0.000000 457s [596] 17.251020 0.000000 6.560821 9.671438 9.671438 0.000000 0.000000 457s [603] 0.000000 12.605469 17.251020 12.605469 12.605469 6.560821 6.560821 457s [610] 15.892672 3.382287 6.560821 6.560821 9.671438 17.251020 17.251020 457s [617] 0.000000 3.382287 12.605469 15.892672 3.382287 0.000000 17.251020 457s [624] 12.605469 6.560821 17.251020 17.251020 0.000000 6.560821 15.892672 457s [631] 6.560821 6.560821 0.000000 15.892672 17.251020 0.000000 3.382287 457s [638] 17.251020 457s 457s $se.fit 457s [1] 0.1322852 0.2566014 0.4930147 0.4930147 0.6747076 0.0000000 0.0000000 457s [8] 0.2566014 0.6747076 0.1322852 0.6215810 0.1322852 0.0000000 0.3782613 457s [15] 0.6215810 0.6747076 0.4930147 0.6747076 0.1322852 0.6747076 0.6747076 457s [22] 0.3782613 0.1322852 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 457s [29] 0.0000000 0.6747076 0.0000000 0.3782613 0.4930147 0.1322852 0.1322852 457s [36] 0.0000000 0.0000000 0.4930147 0.0000000 0.4930147 0.0000000 0.6215810 457s [43] 0.4930147 0.6215810 0.1322852 0.6747076 0.6747076 0.2566014 0.1322852 457s [50] 0.0000000 0.3782613 0.6747076 0.6215810 0.0000000 0.1322852 0.6747076 457s [57] 0.2566014 0.6747076 0.0000000 0.1322852 0.4930147 0.4930147 0.0000000 457s [64] 0.0000000 0.6215810 0.6215810 0.0000000 0.4930147 0.6215810 0.1322852 457s [71] 0.6215810 0.2566014 0.1322852 0.6747076 0.4930147 0.0000000 0.4930147 457s [78] 0.4930147 0.1322852 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 457s [85] 0.1322852 0.2566014 0.1322852 0.0000000 0.1322852 0.6747076 0.2566014 457s [92] 0.1322852 0.6747076 0.3782613 0.1322852 0.0000000 0.1322852 0.1322852 457s [99] 0.4930147 0.0000000 0.1322852 0.1322852 0.4930147 0.0000000 0.0000000 457s [106] 0.6747076 0.0000000 0.2566014 0.6215810 0.6747076 0.1322852 0.6747076 457s [113] 0.1322852 0.0000000 0.0000000 0.1322852 0.2566014 0.0000000 0.2566014 457s [120] 0.1322852 0.0000000 0.0000000 0.2566014 0.6215810 0.4930147 0.4930147 457s [127] 0.0000000 0.6747076 0.0000000 0.6747076 0.1322852 0.0000000 0.4930147 457s [134] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.2566014 0.2566014 457s [141] 0.1322852 0.6747076 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 457s [148] 0.6747076 0.1322852 0.6215810 0.0000000 0.6747076 0.2566014 0.1322852 457s [155] 0.4930147 0.2566014 0.2566014 0.1322852 0.1322852 0.0000000 0.1322852 457s [162] 0.0000000 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.0000000 457s [169] 0.0000000 0.1322852 0.6747076 0.1322852 0.6747076 0.6215810 0.2566014 457s [176] 0.4930147 0.1322852 0.0000000 0.4930147 0.0000000 0.4930147 0.6747076 457s [183] 0.4930147 0.0000000 0.0000000 0.4930147 0.1322852 0.4930147 0.6747076 457s [190] 0.1322852 0.1322852 0.6747076 0.1322852 0.2566014 0.1322852 0.6747076 457s [197] 0.6747076 0.0000000 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 457s [204] 0.4930147 0.4930147 0.1322852 0.1322852 0.4930147 0.6747076 0.4930147 457s [211] 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.1322852 0.1322852 457s [218] 0.0000000 0.2566014 0.0000000 0.2566014 0.2566014 0.1322852 0.0000000 457s [225] 0.1322852 0.1322852 0.6747076 0.1322852 0.0000000 0.6747076 0.1322852 457s [232] 0.2566014 0.6747076 0.0000000 0.0000000 0.1322852 0.1322852 0.4930147 457s [239] 0.2566014 0.4930147 0.1322852 0.4930147 0.6747076 0.2566014 0.6747076 457s [246] 0.6747076 0.6215810 0.0000000 0.1322852 0.1322852 0.1322852 0.0000000 457s [253] 0.4930147 0.6215810 0.2566014 0.1322852 0.1322852 0.0000000 0.0000000 457s [260] 0.4930147 0.2566014 0.1322852 0.1322852 0.4930147 0.6747076 0.0000000 457s [267] 0.2566014 0.6215810 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 457s [274] 0.6747076 0.6215810 0.2566014 0.1322852 0.4930147 0.0000000 0.1322852 457s [281] 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.6215810 0.6747076 457s [288] 0.1322852 0.6747076 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 457s [295] 0.0000000 0.6747076 0.6747076 0.4930147 0.0000000 0.4930147 0.6747076 457s [302] 0.6215810 0.6215810 0.0000000 0.1322852 0.4930147 0.4930147 0.6215810 457s [309] 0.2566014 0.6215810 0.4930147 0.4930147 0.6747076 0.0000000 0.6747076 457s [316] 0.1322852 0.6747076 0.1322852 0.4930147 0.0000000 0.2566014 0.1322852 457s [323] 0.0000000 0.6215810 0.6747076 0.6747076 0.6747076 0.1322852 0.2566014 457s [330] 0.0000000 0.0000000 0.4930147 0.4930147 0.4930147 0.0000000 0.4930147 457s [337] 0.0000000 0.6215810 0.2566014 0.6747076 0.4930147 0.4930147 0.2566014 457s [344] 0.0000000 0.0000000 0.6747076 0.0000000 0.0000000 0.4930147 0.0000000 457s [351] 0.1322852 0.1322852 0.2566014 0.6747076 0.3782613 0.0000000 0.3782613 457s [358] 0.3782613 0.4930147 0.1322852 0.4930147 0.1322852 0.6747076 0.0000000 457s [365] 0.4930147 0.0000000 0.1322852 0.0000000 0.1322852 0.2566014 0.0000000 457s [372] 0.2566014 0.2566014 0.6747076 0.6215810 0.0000000 0.6747076 0.0000000 457s [379] 0.1322852 0.6747076 0.1322852 0.4930147 0.1322852 0.1322852 0.4930147 457s [386] 0.1322852 0.1322852 0.0000000 0.6215810 0.0000000 0.4930147 0.0000000 457s [393] 0.6215810 0.2566014 0.6215810 0.6215810 0.2566014 0.2566014 0.1322852 457s [400] 0.1322852 0.6747076 0.6747076 0.2566014 0.4930147 0.3782613 0.6215810 457s [407] 0.6747076 0.2566014 0.1322852 0.0000000 0.2566014 0.2566014 0.6215810 457s [414] 0.1322852 0.0000000 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 457s [421] 0.0000000 0.1322852 0.1322852 0.4930147 0.6747076 0.6747076 0.6747076 457s [428] 0.0000000 0.6215810 0.6747076 0.6747076 0.0000000 0.0000000 0.6747076 457s [435] 0.4930147 0.2566014 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 457s [442] 0.4930147 0.6747076 0.1322852 0.4930147 0.0000000 0.6747076 0.0000000 457s [449] 0.2566014 0.4930147 0.2566014 0.4930147 0.6215810 0.4930147 0.4930147 457s [456] 0.0000000 0.0000000 0.1322852 0.0000000 0.1322852 0.0000000 0.0000000 457s [463] 0.0000000 0.6747076 0.2566014 0.6747076 0.4930147 0.4930147 0.1322852 457s [470] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.0000000 0.0000000 457s [477] 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 0.1322852 0.4930147 457s [484] 0.2566014 0.6747076 0.3782613 0.6215810 0.6747076 0.6215810 0.0000000 457s [491] 0.0000000 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.4930147 457s [498] 0.4930147 0.4930147 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 457s [505] 0.2566014 0.1322852 0.6747076 0.1322852 0.4930147 0.4930147 0.6215810 457s [512] 0.0000000 0.4930147 0.6747076 0.2566014 0.0000000 0.1322852 0.0000000 457s [519] 0.6215810 0.0000000 0.4930147 0.4930147 0.0000000 0.6747076 0.0000000 457s [526] 0.3782613 0.0000000 0.1322852 0.6215810 0.1322852 0.1322852 0.1322852 457s [533] 0.6747076 0.6215810 0.0000000 0.0000000 0.0000000 0.6215810 0.2566014 457s [540] 0.6747076 0.6747076 0.2566014 0.0000000 0.0000000 0.1322852 0.4930147 457s [547] 0.4930147 0.0000000 0.1322852 0.6215810 0.0000000 0.0000000 0.1322852 457s [554] 0.0000000 0.0000000 0.0000000 0.6747076 0.6747076 0.6747076 0.4930147 457s [561] 0.0000000 0.6215810 0.0000000 0.1322852 0.1322852 0.4930147 0.2566014 457s [568] 0.4930147 0.1322852 0.1322852 0.0000000 0.6747076 0.2566014 0.6215810 457s [575] 0.0000000 0.3782613 0.1322852 0.1322852 0.0000000 0.4930147 0.1322852 457s [582] 0.4930147 0.1322852 0.0000000 0.2566014 0.0000000 0.1322852 0.6747076 457s [589] 0.1322852 0.4930147 0.4930147 0.6747076 0.1322852 0.3782613 0.0000000 457s [596] 0.6747076 0.0000000 0.2566014 0.3782613 0.3782613 0.0000000 0.0000000 457s [603] 0.0000000 0.4930147 0.6747076 0.4930147 0.4930147 0.2566014 0.2566014 457s [610] 0.6215810 0.1322852 0.2566014 0.2566014 0.3782613 0.6747076 0.6747076 457s [617] 0.0000000 0.1322852 0.4930147 0.6215810 0.1322852 0.0000000 0.6747076 457s [624] 0.4930147 0.2566014 0.6747076 0.6747076 0.0000000 0.2566014 0.6215810 457s [631] 0.2566014 0.2566014 0.0000000 0.6215810 0.6747076 0.0000000 0.1322852 457s [638] 0.6747076 457s 457s [1] 73.61884 457s [1] 4193.584 457s [1] 4193.584 457s Dose Response Model 457s 457s Model: linear 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -19.855 -3.996 -0.064 3.775 24.956 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -11.1996 0.811196 457s delta 0.0136 0.000532 457s age -0.0126 0.009027 457s centergreen 0.0191 0.793736 457s centerred 1.1979 0.810341 457s centersilver 0.7446 0.817870 457s centeryellow 1.2027 0.826882 457s 457s Residual standard error: 6.43 457s Degrees of freedom: 631 457s 457s Call: 457s lm(formula = y ~ x + age + center, data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -24.956 -3.775 0.064 3.996 19.855 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -1.120e+01 8.112e-01 -13.806 <2e-16 *** 457s x 1.360e-02 5.316e-04 25.575 <2e-16 *** 457s age -1.255e-02 9.027e-03 -1.391 0.165 457s centergreen 1.906e-02 7.937e-01 0.024 0.981 457s centerred 1.198e+00 8.103e-01 1.478 0.140 457s centersilver 7.446e-01 8.179e-01 0.910 0.363 457s centeryellow 1.203e+00 8.269e-01 1.455 0.146 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 6.427 on 631 degrees of freedom 457s Multiple R-squared: 0.5116, Adjusted R-squared: 0.507 457s F-statistic: 110.2 on 6 and 631 DF, p-value: < 2.2e-16 457s 457s e0 delta age centergreen 457s e0 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 457s delta -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 457s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 457s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 457s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 457s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 457s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 457s centerred centersilver centeryellow 457s e0 -3.460807e-01 -3.642369e-01 -3.253015e-01 457s delta -1.885394e-06 1.847581e-05 3.596102e-06 457s age 2.140485e-04 3.347250e-04 -2.387489e-04 457s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 457s centerred 6.566532e-01 3.366063e-01 3.351988e-01 457s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 457s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 457s (Intercept) x age centergreen 457s (Intercept) 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 457s x -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 457s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 457s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 457s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 457s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 457s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 457s centerred centersilver centeryellow 457s (Intercept) -3.460807e-01 -3.642369e-01 -3.253015e-01 457s x -1.885394e-06 1.847581e-05 3.596102e-06 457s age 2.140485e-04 3.347250e-04 -2.387489e-04 457s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 457s centerred 6.566532e-01 3.366063e-01 3.351988e-01 457s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 457s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 457s $fit 457s [1] 3.385405 6.566871 12.617093 12.617093 17.266927 0.000000 0.000000 457s [8] 6.566871 17.266927 3.385405 15.907326 3.385405 0.000000 9.680356 457s [15] 15.907326 17.266927 12.617093 17.266927 3.385405 17.266927 17.266927 457s [22] 9.680356 3.385405 12.617093 0.000000 12.617093 3.385405 6.566871 457s [29] 0.000000 17.266927 0.000000 9.680356 12.617093 3.385405 3.385405 457s [36] 0.000000 0.000000 12.617093 0.000000 12.617093 0.000000 15.907326 457s [43] 12.617093 15.907326 3.385405 17.266927 17.266927 6.566871 3.385405 457s [50] 0.000000 9.680356 17.266927 15.907326 0.000000 3.385405 17.266927 457s [57] 6.566871 17.266927 0.000000 3.385405 12.617093 12.617093 0.000000 457s [64] 0.000000 15.907326 15.907326 0.000000 12.617093 15.907326 3.385405 457s [71] 15.907326 6.566871 3.385405 17.266927 12.617093 0.000000 12.617093 457s [78] 12.617093 3.385405 0.000000 0.000000 0.000000 3.385405 3.385405 457s [85] 3.385405 6.566871 3.385405 0.000000 3.385405 17.266927 6.566871 457s [92] 3.385405 17.266927 9.680356 3.385405 0.000000 3.385405 3.385405 457s [99] 12.617093 0.000000 3.385405 3.385405 12.617093 0.000000 0.000000 457s [106] 17.266927 0.000000 6.566871 15.907326 17.266927 3.385405 17.266927 457s [113] 3.385405 0.000000 0.000000 3.385405 6.566871 0.000000 6.566871 457s [120] 3.385405 0.000000 0.000000 6.566871 15.907326 12.617093 12.617093 457s [127] 0.000000 17.266927 0.000000 17.266927 3.385405 0.000000 12.617093 457s [134] 17.266927 0.000000 3.385405 0.000000 6.566871 6.566871 6.566871 457s [141] 3.385405 17.266927 0.000000 0.000000 3.385405 0.000000 15.907326 457s [148] 17.266927 3.385405 15.907326 0.000000 17.266927 6.566871 3.385405 457s [155] 12.617093 6.566871 6.566871 3.385405 3.385405 0.000000 3.385405 457s [162] 0.000000 3.385405 12.617093 3.385405 0.000000 17.266927 0.000000 457s [169] 0.000000 3.385405 17.266927 3.385405 17.266927 15.907326 6.566871 457s [176] 12.617093 3.385405 0.000000 12.617093 0.000000 12.617093 17.266927 457s [183] 12.617093 0.000000 0.000000 12.617093 3.385405 12.617093 17.266927 457s [190] 3.385405 3.385405 17.266927 3.385405 6.566871 3.385405 17.266927 457s [197] 17.266927 0.000000 12.617093 0.000000 12.617093 3.385405 6.566871 457s [204] 12.617093 12.617093 3.385405 3.385405 12.617093 17.266927 12.617093 457s [211] 3.385405 3.385405 17.266927 0.000000 6.566871 3.385405 3.385405 457s [218] 0.000000 6.566871 0.000000 6.566871 6.566871 3.385405 0.000000 457s [225] 3.385405 3.385405 17.266927 3.385405 0.000000 17.266927 3.385405 457s [232] 6.566871 17.266927 0.000000 0.000000 3.385405 3.385405 12.617093 457s [239] 6.566871 12.617093 3.385405 12.617093 17.266927 6.566871 17.266927 457s [246] 17.266927 15.907326 0.000000 3.385405 3.385405 3.385405 0.000000 457s [253] 12.617093 15.907326 6.566871 3.385405 3.385405 0.000000 0.000000 457s [260] 12.617093 6.566871 3.385405 3.385405 12.617093 17.266927 0.000000 457s [267] 6.566871 15.907326 3.385405 15.907326 3.385405 12.617093 0.000000 457s [274] 17.266927 15.907326 6.566871 3.385405 12.617093 0.000000 3.385405 457s [281] 3.385405 12.617093 3.385405 0.000000 17.266927 15.907326 17.266927 457s [288] 3.385405 17.266927 3.385405 3.385405 3.385405 15.907326 0.000000 457s [295] 0.000000 17.266927 17.266927 12.617093 0.000000 12.617093 17.266927 457s [302] 15.907326 15.907326 0.000000 3.385405 12.617093 12.617093 15.907326 457s [309] 6.566871 15.907326 12.617093 12.617093 17.266927 0.000000 17.266927 457s [316] 3.385405 17.266927 3.385405 12.617093 0.000000 6.566871 3.385405 457s [323] 0.000000 15.907326 17.266927 17.266927 17.266927 3.385405 6.566871 457s [330] 0.000000 0.000000 12.617093 12.617093 12.617093 0.000000 12.617093 457s [337] 0.000000 15.907326 6.566871 17.266927 12.617093 12.617093 6.566871 457s [344] 0.000000 0.000000 17.266927 0.000000 0.000000 12.617093 0.000000 457s [351] 3.385405 3.385405 6.566871 17.266927 9.680356 0.000000 9.680356 457s [358] 9.680356 12.617093 3.385405 12.617093 3.385405 17.266927 0.000000 457s [365] 12.617093 0.000000 3.385405 0.000000 3.385405 6.566871 0.000000 457s [372] 6.566871 6.566871 17.266927 15.907326 0.000000 17.266927 0.000000 457s [379] 3.385405 17.266927 3.385405 12.617093 3.385405 3.385405 12.617093 457s [386] 3.385405 3.385405 0.000000 15.907326 0.000000 12.617093 0.000000 457s [393] 15.907326 6.566871 15.907326 15.907326 6.566871 6.566871 3.385405 457s [400] 3.385405 17.266927 17.266927 6.566871 12.617093 9.680356 15.907326 457s [407] 17.266927 6.566871 3.385405 0.000000 6.566871 6.566871 15.907326 457s [414] 3.385405 0.000000 0.000000 0.000000 0.000000 3.385405 3.385405 457s [421] 0.000000 3.385405 3.385405 12.617093 17.266927 17.266927 17.266927 457s [428] 0.000000 15.907326 17.266927 17.266927 0.000000 0.000000 17.266927 457s [435] 12.617093 6.566871 0.000000 0.000000 3.385405 0.000000 15.907326 457s [442] 12.617093 17.266927 3.385405 12.617093 0.000000 17.266927 0.000000 457s [449] 6.566871 12.617093 6.566871 12.617093 15.907326 12.617093 12.617093 457s [456] 0.000000 0.000000 3.385405 0.000000 3.385405 0.000000 0.000000 457s [463] 0.000000 17.266927 6.566871 17.266927 12.617093 12.617093 3.385405 457s [470] 17.266927 0.000000 3.385405 0.000000 6.566871 0.000000 0.000000 457s [477] 3.385405 15.907326 3.385405 12.617093 0.000000 3.385405 12.617093 457s [484] 6.566871 17.266927 9.680356 15.907326 17.266927 15.907326 0.000000 457s [491] 0.000000 3.385405 3.385405 17.266927 0.000000 6.566871 12.617093 457s [498] 12.617093 12.617093 3.385405 3.385405 3.385405 15.907326 0.000000 457s [505] 6.566871 3.385405 17.266927 3.385405 12.617093 12.617093 15.907326 457s [512] 0.000000 12.617093 17.266927 6.566871 0.000000 3.385405 0.000000 457s [519] 15.907326 0.000000 12.617093 12.617093 0.000000 17.266927 0.000000 457s [526] 9.680356 0.000000 3.385405 15.907326 3.385405 3.385405 3.385405 457s [533] 17.266927 15.907326 0.000000 0.000000 0.000000 15.907326 6.566871 457s [540] 17.266927 17.266927 6.566871 0.000000 0.000000 3.385405 12.617093 457s [547] 12.617093 0.000000 3.385405 15.907326 0.000000 0.000000 3.385405 457s [554] 0.000000 0.000000 0.000000 17.266927 17.266927 17.266927 12.617093 457s [561] 0.000000 15.907326 0.000000 3.385405 3.385405 12.617093 6.566871 457s [568] 12.617093 3.385405 3.385405 0.000000 17.266927 6.566871 15.907326 457s [575] 0.000000 9.680356 3.385405 3.385405 0.000000 12.617093 3.385405 457s [582] 12.617093 3.385405 0.000000 6.566871 0.000000 3.385405 17.266927 457s [589] 3.385405 12.617093 12.617093 17.266927 3.385405 9.680356 0.000000 457s [596] 17.266927 0.000000 6.566871 9.680356 9.680356 0.000000 0.000000 457s [603] 0.000000 12.617093 17.266927 12.617093 12.617093 6.566871 6.566871 457s [610] 15.907326 3.385405 6.566871 6.566871 9.680356 17.266927 17.266927 457s [617] 0.000000 3.385405 12.617093 15.907326 3.385405 0.000000 17.266927 457s [624] 12.617093 6.566871 17.266927 17.266927 0.000000 6.566871 15.907326 457s [631] 6.566871 6.566871 0.000000 15.907326 17.266927 0.000000 3.385405 457s [638] 17.266927 457s 457s $se.fit 457s [1] 0.1323718 0.2567693 0.4933373 0.4933373 0.6751491 0.0000000 0.0000000 457s [8] 0.2567693 0.6751491 0.1323718 0.6219878 0.1323718 0.0000000 0.3785088 457s [15] 0.6219878 0.6751491 0.4933373 0.6751491 0.1323718 0.6751491 0.6751491 457s [22] 0.3785088 0.1323718 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 457s [29] 0.0000000 0.6751491 0.0000000 0.3785088 0.4933373 0.1323718 0.1323718 457s [36] 0.0000000 0.0000000 0.4933373 0.0000000 0.4933373 0.0000000 0.6219878 457s [43] 0.4933373 0.6219878 0.1323718 0.6751491 0.6751491 0.2567693 0.1323718 457s [50] 0.0000000 0.3785088 0.6751491 0.6219878 0.0000000 0.1323718 0.6751491 457s [57] 0.2567693 0.6751491 0.0000000 0.1323718 0.4933373 0.4933373 0.0000000 457s [64] 0.0000000 0.6219878 0.6219878 0.0000000 0.4933373 0.6219878 0.1323718 457s [71] 0.6219878 0.2567693 0.1323718 0.6751491 0.4933373 0.0000000 0.4933373 457s [78] 0.4933373 0.1323718 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 457s [85] 0.1323718 0.2567693 0.1323718 0.0000000 0.1323718 0.6751491 0.2567693 457s [92] 0.1323718 0.6751491 0.3785088 0.1323718 0.0000000 0.1323718 0.1323718 457s [99] 0.4933373 0.0000000 0.1323718 0.1323718 0.4933373 0.0000000 0.0000000 457s [106] 0.6751491 0.0000000 0.2567693 0.6219878 0.6751491 0.1323718 0.6751491 457s [113] 0.1323718 0.0000000 0.0000000 0.1323718 0.2567693 0.0000000 0.2567693 457s [120] 0.1323718 0.0000000 0.0000000 0.2567693 0.6219878 0.4933373 0.4933373 457s [127] 0.0000000 0.6751491 0.0000000 0.6751491 0.1323718 0.0000000 0.4933373 457s [134] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.2567693 0.2567693 457s [141] 0.1323718 0.6751491 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 457s [148] 0.6751491 0.1323718 0.6219878 0.0000000 0.6751491 0.2567693 0.1323718 457s [155] 0.4933373 0.2567693 0.2567693 0.1323718 0.1323718 0.0000000 0.1323718 457s [162] 0.0000000 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.0000000 457s [169] 0.0000000 0.1323718 0.6751491 0.1323718 0.6751491 0.6219878 0.2567693 457s [176] 0.4933373 0.1323718 0.0000000 0.4933373 0.0000000 0.4933373 0.6751491 457s [183] 0.4933373 0.0000000 0.0000000 0.4933373 0.1323718 0.4933373 0.6751491 457s [190] 0.1323718 0.1323718 0.6751491 0.1323718 0.2567693 0.1323718 0.6751491 457s [197] 0.6751491 0.0000000 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 457s [204] 0.4933373 0.4933373 0.1323718 0.1323718 0.4933373 0.6751491 0.4933373 457s [211] 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.1323718 0.1323718 457s [218] 0.0000000 0.2567693 0.0000000 0.2567693 0.2567693 0.1323718 0.0000000 457s [225] 0.1323718 0.1323718 0.6751491 0.1323718 0.0000000 0.6751491 0.1323718 457s [232] 0.2567693 0.6751491 0.0000000 0.0000000 0.1323718 0.1323718 0.4933373 457s [239] 0.2567693 0.4933373 0.1323718 0.4933373 0.6751491 0.2567693 0.6751491 457s [246] 0.6751491 0.6219878 0.0000000 0.1323718 0.1323718 0.1323718 0.0000000 457s [253] 0.4933373 0.6219878 0.2567693 0.1323718 0.1323718 0.0000000 0.0000000 457s [260] 0.4933373 0.2567693 0.1323718 0.1323718 0.4933373 0.6751491 0.0000000 457s [267] 0.2567693 0.6219878 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 457s [274] 0.6751491 0.6219878 0.2567693 0.1323718 0.4933373 0.0000000 0.1323718 457s [281] 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.6219878 0.6751491 457s [288] 0.1323718 0.6751491 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 457s [295] 0.0000000 0.6751491 0.6751491 0.4933373 0.0000000 0.4933373 0.6751491 457s [302] 0.6219878 0.6219878 0.0000000 0.1323718 0.4933373 0.4933373 0.6219878 457s [309] 0.2567693 0.6219878 0.4933373 0.4933373 0.6751491 0.0000000 0.6751491 457s [316] 0.1323718 0.6751491 0.1323718 0.4933373 0.0000000 0.2567693 0.1323718 457s [323] 0.0000000 0.6219878 0.6751491 0.6751491 0.6751491 0.1323718 0.2567693 457s [330] 0.0000000 0.0000000 0.4933373 0.4933373 0.4933373 0.0000000 0.4933373 457s [337] 0.0000000 0.6219878 0.2567693 0.6751491 0.4933373 0.4933373 0.2567693 457s [344] 0.0000000 0.0000000 0.6751491 0.0000000 0.0000000 0.4933373 0.0000000 457s [351] 0.1323718 0.1323718 0.2567693 0.6751491 0.3785088 0.0000000 0.3785088 457s [358] 0.3785088 0.4933373 0.1323718 0.4933373 0.1323718 0.6751491 0.0000000 457s [365] 0.4933373 0.0000000 0.1323718 0.0000000 0.1323718 0.2567693 0.0000000 457s [372] 0.2567693 0.2567693 0.6751491 0.6219878 0.0000000 0.6751491 0.0000000 457s [379] 0.1323718 0.6751491 0.1323718 0.4933373 0.1323718 0.1323718 0.4933373 457s [386] 0.1323718 0.1323718 0.0000000 0.6219878 0.0000000 0.4933373 0.0000000 457s [393] 0.6219878 0.2567693 0.6219878 0.6219878 0.2567693 0.2567693 0.1323718 457s [400] 0.1323718 0.6751491 0.6751491 0.2567693 0.4933373 0.3785088 0.6219878 457s [407] 0.6751491 0.2567693 0.1323718 0.0000000 0.2567693 0.2567693 0.6219878 457s [414] 0.1323718 0.0000000 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 457s [421] 0.0000000 0.1323718 0.1323718 0.4933373 0.6751491 0.6751491 0.6751491 457s [428] 0.0000000 0.6219878 0.6751491 0.6751491 0.0000000 0.0000000 0.6751491 457s [435] 0.4933373 0.2567693 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 457s [442] 0.4933373 0.6751491 0.1323718 0.4933373 0.0000000 0.6751491 0.0000000 457s [449] 0.2567693 0.4933373 0.2567693 0.4933373 0.6219878 0.4933373 0.4933373 457s [456] 0.0000000 0.0000000 0.1323718 0.0000000 0.1323718 0.0000000 0.0000000 457s [463] 0.0000000 0.6751491 0.2567693 0.6751491 0.4933373 0.4933373 0.1323718 457s [470] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.0000000 0.0000000 457s [477] 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 0.1323718 0.4933373 457s [484] 0.2567693 0.6751491 0.3785088 0.6219878 0.6751491 0.6219878 0.0000000 457s [491] 0.0000000 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.4933373 457s [498] 0.4933373 0.4933373 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 457s [505] 0.2567693 0.1323718 0.6751491 0.1323718 0.4933373 0.4933373 0.6219878 457s [512] 0.0000000 0.4933373 0.6751491 0.2567693 0.0000000 0.1323718 0.0000000 457s [519] 0.6219878 0.0000000 0.4933373 0.4933373 0.0000000 0.6751491 0.0000000 457s [526] 0.3785088 0.0000000 0.1323718 0.6219878 0.1323718 0.1323718 0.1323718 457s [533] 0.6751491 0.6219878 0.0000000 0.0000000 0.0000000 0.6219878 0.2567693 457s [540] 0.6751491 0.6751491 0.2567693 0.0000000 0.0000000 0.1323718 0.4933373 457s [547] 0.4933373 0.0000000 0.1323718 0.6219878 0.0000000 0.0000000 0.1323718 457s [554] 0.0000000 0.0000000 0.0000000 0.6751491 0.6751491 0.6751491 0.4933373 457s [561] 0.0000000 0.6219878 0.0000000 0.1323718 0.1323718 0.4933373 0.2567693 457s [568] 0.4933373 0.1323718 0.1323718 0.0000000 0.6751491 0.2567693 0.6219878 457s [575] 0.0000000 0.3785088 0.1323718 0.1323718 0.0000000 0.4933373 0.1323718 457s [582] 0.4933373 0.1323718 0.0000000 0.2567693 0.0000000 0.1323718 0.6751491 457s [589] 0.1323718 0.4933373 0.4933373 0.6751491 0.1323718 0.3785088 0.0000000 457s [596] 0.6751491 0.0000000 0.2567693 0.3785088 0.3785088 0.0000000 0.0000000 457s [603] 0.0000000 0.4933373 0.6751491 0.4933373 0.4933373 0.2567693 0.2567693 457s [610] 0.6219878 0.1323718 0.2567693 0.2567693 0.3785088 0.6751491 0.6751491 457s [617] 0.0000000 0.1323718 0.4933373 0.6219878 0.1323718 0.0000000 0.6751491 457s [624] 0.4933373 0.2567693 0.6751491 0.6751491 0.0000000 0.2567693 0.6219878 457s [631] 0.2567693 0.2567693 0.0000000 0.6219878 0.6751491 0.0000000 0.1323718 457s [638] 0.6751491 457s 457s $fit 457s [1] -11.57621 -11.56261 -11.54901 -10.21661 457s 457s $se.fit 457s [1] 0.6876991 0.6874618 0.6872248 0.6656515 457s 457s $fit 457s 1 2 3 4 457s -11.57621 -11.56261 -11.54901 -10.21661 457s 457s $se.fit 457s 1 2 3 4 457s 0.6876991 0.6874618 0.6872248 0.6656515 457s 457s $df 457s [1] 631 457s 457s $residual.scale 457s [1] 6.427248 457s 457s [1] 73.55102 457s [1] 2768.739 457s [1] 2768.739 457s Dose Response Model 457s 457s Model: linlog 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -18.804 -3.875 -0.163 4.453 17.258 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -13.65 2.626 457s delta 2.21 0.402 457s 457s Residual standard error: 6.12 457s Degrees of freedom: 426 457s 457s Call: 457s lm(formula = y ~ log(x + off), data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -17.2582 -4.4526 0.1627 3.8749 18.8035 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -13.6486 2.6260 -5.197 3.14e-07 *** 457s log(x + off) 2.2117 0.4016 5.508 6.29e-08 *** 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 6.116 on 426 degrees of freedom 457s Multiple R-squared: 0.06648, Adjusted R-squared: 0.06429 457s F-statistic: 30.34 on 1 and 426 DF, p-value: 6.29e-08 457s 457s e0 delta 457s e0 6.896082 -1.0477868 457s delta -1.047787 0.1612436 457s (Intercept) log(x + off) 457s (Intercept) 6.896082 -1.0477868 457s log(x + off) -1.047787 0.1612436 457s $fit 457s [1] 6.008369 5.658359 0.000000 4.514640 4.877164 4.115493 6.008369 6.641510 457s [9] 0.000000 4.115493 5.658359 6.247655 4.514640 6.247655 4.514640 4.514640 457s [17] 4.115493 0.000000 6.008369 4.877164 4.877164 6.247655 6.733679 6.247655 457s [25] 4.115493 4.877164 0.000000 6.733679 6.641510 4.514640 4.514640 5.658359 457s [33] 6.008369 4.877164 4.877164 0.000000 6.008369 6.733679 4.877164 6.008369 457s [41] 6.733679 4.877164 6.008369 6.008369 4.877164 5.658359 4.514640 4.877164 457s [49] 0.000000 4.514640 5.658359 0.000000 4.877164 6.733679 4.877164 4.514640 457s [57] 4.877164 5.658359 6.641510 4.877164 6.733679 5.658359 0.000000 6.247655 457s [65] 6.247655 5.658359 4.877164 4.877164 4.115493 4.877164 6.733679 6.247655 457s [73] 5.658359 5.658359 4.877164 5.535104 6.008369 5.535104 6.247655 6.008369 457s [81] 6.247655 6.008369 5.535104 4.115493 5.658359 4.877164 6.008369 4.877164 457s [89] 6.247655 0.000000 6.008369 4.514640 4.514640 6.008369 4.877164 5.658359 457s [97] 4.877164 6.008369 6.733679 5.658359 4.115493 6.247655 0.000000 6.008369 457s [105] 6.247655 4.877164 6.733679 5.658359 4.115493 5.658359 5.658359 5.658359 457s [113] 6.008369 6.008369 6.733679 4.115493 4.877164 4.115493 4.877164 5.658359 457s [121] 4.514640 6.247655 4.877164 6.641510 4.115493 4.877164 5.658359 4.877164 457s [129] 4.514640 0.000000 6.008369 4.514640 6.733679 4.877164 4.514640 4.877164 457s [137] 5.658359 5.658359 4.115493 6.247655 6.641510 4.877164 5.658359 4.514640 457s [145] 4.115493 4.115493 6.733679 4.877164 0.000000 4.877164 5.658359 4.514640 457s [153] 6.641510 4.514640 4.877164 4.115493 6.247655 4.115493 6.008369 4.877164 457s [161] 4.514640 4.115493 4.877164 6.733679 6.247655 4.514640 4.877164 5.658359 457s [169] 4.115493 0.000000 5.658359 5.658359 4.877164 4.514640 4.115493 4.877164 457s [177] 0.000000 5.658359 6.247655 6.733679 0.000000 6.008369 4.514640 4.877164 457s [185] 0.000000 6.733679 5.658359 6.247655 4.514640 5.535104 5.658359 4.877164 457s [193] 5.658359 6.733679 6.641510 4.514640 6.008369 4.115493 4.877164 4.877164 457s [201] 4.115493 6.247655 5.658359 6.247655 5.535104 0.000000 4.115493 6.641510 457s [209] 6.247655 6.008369 4.115493 4.514640 4.514640 6.641510 6.733679 6.733679 457s [217] 5.658359 5.658359 6.008369 4.115493 5.658359 6.641510 6.641510 4.877164 457s [225] 0.000000 4.877164 0.000000 4.115493 4.877164 5.535104 4.115493 5.658359 457s [233] 6.733679 4.514640 6.733679 4.514640 4.514640 5.658359 6.008369 5.658359 457s [241] 4.877164 4.514640 4.115493 4.115493 4.115493 6.247655 5.658359 0.000000 457s [249] 4.115493 4.514640 6.247655 6.733679 6.008369 4.877164 4.115493 4.514640 457s [257] 0.000000 0.000000 5.658359 5.658359 4.514640 5.658359 4.514640 4.115493 457s [265] 4.877164 4.877164 4.514640 5.658359 6.008369 4.514640 4.115493 0.000000 457s [273] 4.877164 4.877164 4.115493 6.008369 4.514640 6.008369 4.514640 4.877164 457s [281] 6.008369 0.000000 0.000000 5.658359 6.247655 6.008369 6.008369 6.247655 457s [289] 4.877164 4.877164 4.514640 6.008369 6.008369 4.115493 6.641510 6.733679 457s [297] 4.514640 4.877164 4.877164 4.877164 6.008369 6.641510 4.877164 5.658359 457s [305] 4.514640 5.535104 4.877164 6.008369 6.008369 5.658359 4.514640 6.008369 457s [313] 6.247655 5.658359 6.733679 6.008369 6.247655 5.658359 5.535104 4.877164 457s [321] 5.658359 4.877164 4.877164 5.658359 5.658359 4.877164 4.115493 4.877164 457s [329] 5.658359 4.877164 4.877164 4.877164 5.658359 6.733679 6.008369 6.247655 457s [337] 4.877164 5.535104 6.008369 4.115493 6.008369 6.247655 4.115493 6.008369 457s [345] 5.658359 4.877164 6.247655 6.641510 5.658359 4.115493 6.733679 6.008369 457s [353] 5.658359 4.115493 4.514640 4.877164 6.733679 5.658359 0.000000 6.641510 457s [361] 6.733679 4.115493 6.247655 4.877164 4.877164 5.658359 4.514640 4.115493 457s [369] 4.877164 4.877164 4.877164 5.658359 4.877164 0.000000 5.658359 4.877164 457s [377] 4.877164 4.514640 4.514640 6.733679 6.008369 6.733679 4.514640 4.514640 457s [385] 4.115493 5.535104 4.877164 4.877164 6.247655 5.658359 6.733679 4.514640 457s [393] 4.877164 5.658359 6.733679 6.733679 4.514640 6.008369 5.658359 6.733679 457s [401] 6.733679 6.733679 0.000000 6.641510 6.733679 4.115493 4.877164 6.247655 457s [409] 0.000000 4.115493 4.514640 4.877164 4.877164 4.514640 6.733679 6.247655 457s [417] 5.658359 4.877164 4.877164 0.000000 4.877164 4.877164 0.000000 6.008369 457s [425] 4.115493 4.514640 4.877164 0.000000 457s 457s $se.fit 457s [1] 1.0908488 1.0273028 0.0000000 0.8196550 0.8854731 0.7471878 1.0908488 457s [8] 1.2057987 0.0000000 0.7471878 1.0273028 1.1342924 0.8196550 1.1342924 457s [15] 0.8196550 0.8196550 0.7471878 0.0000000 1.0908488 0.8854731 0.8854731 457s [22] 1.1342924 1.2225325 1.1342924 0.7471878 0.8854731 0.0000000 1.2225325 457s [29] 1.2057987 0.8196550 0.8196550 1.0273028 1.0908488 0.8854731 0.8854731 457s [36] 0.0000000 1.0908488 1.2225325 0.8854731 1.0908488 1.2225325 0.8854731 457s [43] 1.0908488 1.0908488 0.8854731 1.0273028 0.8196550 0.8854731 0.0000000 457s [50] 0.8196550 1.0273028 0.0000000 0.8854731 1.2225325 0.8854731 0.8196550 457s [57] 0.8854731 1.0273028 1.2057987 0.8854731 1.2225325 1.0273028 0.0000000 457s [64] 1.1342924 1.1342924 1.0273028 0.8854731 0.8854731 0.7471878 0.8854731 457s [71] 1.2225325 1.1342924 1.0273028 1.0273028 0.8854731 1.0049252 1.0908488 457s [78] 1.0049252 1.1342924 1.0908488 1.1342924 1.0908488 1.0049252 0.7471878 457s [85] 1.0273028 0.8854731 1.0908488 0.8854731 1.1342924 0.0000000 1.0908488 457s [92] 0.8196550 0.8196550 1.0908488 0.8854731 1.0273028 0.8854731 1.0908488 457s [99] 1.2225325 1.0273028 0.7471878 1.1342924 0.0000000 1.0908488 1.1342924 457s [106] 0.8854731 1.2225325 1.0273028 0.7471878 1.0273028 1.0273028 1.0273028 457s [113] 1.0908488 1.0908488 1.2225325 0.7471878 0.8854731 0.7471878 0.8854731 457s [120] 1.0273028 0.8196550 1.1342924 0.8854731 1.2057987 0.7471878 0.8854731 457s [127] 1.0273028 0.8854731 0.8196550 0.0000000 1.0908488 0.8196550 1.2225325 457s [134] 0.8854731 0.8196550 0.8854731 1.0273028 1.0273028 0.7471878 1.1342924 457s [141] 1.2057987 0.8854731 1.0273028 0.8196550 0.7471878 0.7471878 1.2225325 457s [148] 0.8854731 0.0000000 0.8854731 1.0273028 0.8196550 1.2057987 0.8196550 457s [155] 0.8854731 0.7471878 1.1342924 0.7471878 1.0908488 0.8854731 0.8196550 457s [162] 0.7471878 0.8854731 1.2225325 1.1342924 0.8196550 0.8854731 1.0273028 457s [169] 0.7471878 0.0000000 1.0273028 1.0273028 0.8854731 0.8196550 0.7471878 457s [176] 0.8854731 0.0000000 1.0273028 1.1342924 1.2225325 0.0000000 1.0908488 457s [183] 0.8196550 0.8854731 0.0000000 1.2225325 1.0273028 1.1342924 0.8196550 457s [190] 1.0049252 1.0273028 0.8854731 1.0273028 1.2225325 1.2057987 0.8196550 457s [197] 1.0908488 0.7471878 0.8854731 0.8854731 0.7471878 1.1342924 1.0273028 457s [204] 1.1342924 1.0049252 0.0000000 0.7471878 1.2057987 1.1342924 1.0908488 457s [211] 0.7471878 0.8196550 0.8196550 1.2057987 1.2225325 1.2225325 1.0273028 457s [218] 1.0273028 1.0908488 0.7471878 1.0273028 1.2057987 1.2057987 0.8854731 457s [225] 0.0000000 0.8854731 0.0000000 0.7471878 0.8854731 1.0049252 0.7471878 457s [232] 1.0273028 1.2225325 0.8196550 1.2225325 0.8196550 0.8196550 1.0273028 457s [239] 1.0908488 1.0273028 0.8854731 0.8196550 0.7471878 0.7471878 0.7471878 457s [246] 1.1342924 1.0273028 0.0000000 0.7471878 0.8196550 1.1342924 1.2225325 457s [253] 1.0908488 0.8854731 0.7471878 0.8196550 0.0000000 0.0000000 1.0273028 457s [260] 1.0273028 0.8196550 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 457s [267] 0.8196550 1.0273028 1.0908488 0.8196550 0.7471878 0.0000000 0.8854731 457s [274] 0.8854731 0.7471878 1.0908488 0.8196550 1.0908488 0.8196550 0.8854731 457s [281] 1.0908488 0.0000000 0.0000000 1.0273028 1.1342924 1.0908488 1.0908488 457s [288] 1.1342924 0.8854731 0.8854731 0.8196550 1.0908488 1.0908488 0.7471878 457s [295] 1.2057987 1.2225325 0.8196550 0.8854731 0.8854731 0.8854731 1.0908488 457s [302] 1.2057987 0.8854731 1.0273028 0.8196550 1.0049252 0.8854731 1.0908488 457s [309] 1.0908488 1.0273028 0.8196550 1.0908488 1.1342924 1.0273028 1.2225325 457s [316] 1.0908488 1.1342924 1.0273028 1.0049252 0.8854731 1.0273028 0.8854731 457s [323] 0.8854731 1.0273028 1.0273028 0.8854731 0.7471878 0.8854731 1.0273028 457s [330] 0.8854731 0.8854731 0.8854731 1.0273028 1.2225325 1.0908488 1.1342924 457s [337] 0.8854731 1.0049252 1.0908488 0.7471878 1.0908488 1.1342924 0.7471878 457s [344] 1.0908488 1.0273028 0.8854731 1.1342924 1.2057987 1.0273028 0.7471878 457s [351] 1.2225325 1.0908488 1.0273028 0.7471878 0.8196550 0.8854731 1.2225325 457s [358] 1.0273028 0.0000000 1.2057987 1.2225325 0.7471878 1.1342924 0.8854731 457s [365] 0.8854731 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 0.8854731 457s [372] 1.0273028 0.8854731 0.0000000 1.0273028 0.8854731 0.8854731 0.8196550 457s [379] 0.8196550 1.2225325 1.0908488 1.2225325 0.8196550 0.8196550 0.7471878 457s [386] 1.0049252 0.8854731 0.8854731 1.1342924 1.0273028 1.2225325 0.8196550 457s [393] 0.8854731 1.0273028 1.2225325 1.2225325 0.8196550 1.0908488 1.0273028 457s [400] 1.2225325 1.2225325 1.2225325 0.0000000 1.2057987 1.2225325 0.7471878 457s [407] 0.8854731 1.1342924 0.0000000 0.7471878 0.8196550 0.8854731 0.8854731 457s [414] 0.8196550 1.2225325 1.1342924 1.0273028 0.8854731 0.8854731 0.0000000 457s [421] 0.8854731 0.8854731 0.0000000 1.0908488 0.7471878 0.8196550 0.8854731 457s [428] 0.0000000 457s 457s [1] 40.01633 457s [1] 2773.961 457s [1] 2773.961 457s Dose Response Model 457s 457s Model: linlog 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -17.993 -3.920 -0.142 4.548 17.772 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -12.53812 2.7627 457s delta 2.19176 0.4045 457s age -0.00815 0.0103 457s centergreen -0.11764 0.9231 457s centerred -1.68381 0.9385 457s centersilver -0.40779 0.9137 457s centeryellow -0.83235 0.9332 457s 457s Residual standard error: 6.12 457s Degrees of freedom: 421 457s 457s Call: 457s lm(formula = y ~ log(x + off) + age + center, data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -17.7720 -4.5476 0.1417 3.9205 17.9926 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -12.538125 2.762741 -4.538 7.41e-06 *** 457s log(x + off) 2.191761 0.404501 5.418 1.01e-07 *** 457s age -0.008153 0.010337 -0.789 0.4308 457s centergreen -0.117636 0.923131 -0.127 0.8987 457s centerred -1.683810 0.938487 -1.794 0.0735 . 457s centersilver -0.407788 0.913735 -0.446 0.6556 457s centeryellow -0.832351 0.933224 -0.892 0.3730 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 6.118 on 421 degrees of freedom 457s Multiple R-squared: 0.07685, Adjusted R-squared: 0.06369 457s F-statistic: 5.841 on 6 and 421 DF, p-value: 7.284e-06 457s 457s e0 delta age centergreen 457s e0 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 457s delta -1.065954459 0.1636213662 0.0003614495 -0.0285500750 457s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 457s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 457s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 457s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 457s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 457s centerred centersilver centeryellow 457s e0 -0.3271697994 -0.3433662837 -0.3049047728 457s delta -0.0143714026 -0.0139200933 -0.0188552161 457s age 0.0001539174 0.0004143178 0.0002799329 457s centergreen 0.4142785346 0.4148464502 0.4153997441 457s centerred 0.8807582409 0.4133097826 0.4135270947 457s centersilver 0.4133097826 0.8349108233 0.4142615949 457s centeryellow 0.4135270947 0.4142615949 0.8709075166 457s (Intercept) log(x + off) age centergreen 457s (Intercept) 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 457s log(x + off) -1.065954459 0.1636213662 0.0003614495 -0.0285500750 457s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 457s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 457s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 457s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 457s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 457s centerred centersilver centeryellow 457s (Intercept) -0.3271697994 -0.3433662837 -0.3049047728 457s log(x + off) -0.0143714026 -0.0139200933 -0.0188552161 457s age 0.0001539174 0.0004143178 0.0002799329 457s centergreen 0.4142785346 0.4148464502 0.4153997441 457s centerred 0.8807582409 0.4133097826 0.4135270947 457s centersilver 0.4133097826 0.8349108233 0.4142615949 457s centeryellow 0.4135270947 0.4142615949 0.8709075166 457s $fit 457s [1] -3.511779 -3.480690 -3.450035 -1.567022 457s 457s $se.fit 457s [1] 1.1058048 1.1012159 1.0967017 0.8461873 457s 457s $fit 457s 1 2 3 4 457s -3.511779 -3.480690 -3.450035 -1.567022 457s 457s $se.fit 457s 1 2 3 4 457s 1.1058048 1.1012159 1.0967017 0.8461873 457s 457s $df 457s [1] 421 457s 457s $residual.scale 457s [1] 6.117927 457s 457s [1] 40.47058 457s [1] 54.33574 457s [1] 54.33574 457s Dose Response Model 457s 457s Model: quadratic 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -9.08e-01 -3.06e-01 3.08e-05 2.39e-01 7.57e-01 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -3.12e+00 9.19e-02 457s b1 -6.61e-04 1.47e-03 457s b2 5.18e-06 4.40e-06 457s 457s Residual standard error: 0.401 457s Degrees of freedom: 46 457s 457s Call: 457s lm(formula = y ~ x + I(x^2), data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -0.75741 -0.23947 -0.00003 0.30638 0.90831 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -3.118e+00 9.195e-02 -33.914 <2e-16 *** 457s x -6.612e-04 1.466e-03 -0.451 0.654 457s I(x^2) 5.175e-06 4.401e-06 1.176 0.246 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 0.4007 on 46 degrees of freedom 457s Multiple R-squared: 0.1193, Adjusted R-squared: 0.08097 457s F-statistic: 3.115 on 2 and 46 DF, p-value: 0.05388 457s 457s e0 b1 b2 457s e0 8.454726e-03 -7.868733e-05 1.608713e-07 457s b1 -7.868733e-05 2.149290e-06 -6.145868e-09 457s b2 1.608713e-07 -6.145868e-09 1.936461e-11 457s (Intercept) x I(x^2) 457s (Intercept) 8.454726e-03 -7.868733e-05 1.608713e-07 457s x -7.868733e-05 2.149290e-06 -6.145868e-09 457s I(x^2) 1.608713e-07 -6.145868e-09 1.936461e-11 457s $fit 457s [1] 0.49280484 0.00000000 0.05861756 0.00000000 0.25773527 0.00000000 457s [7] 0.05861756 0.00000000 0.25773527 0.05861756 0.25773527 -0.01991690 457s [13] 0.05861756 -0.01991690 0.05861756 0.02376374 0.05861756 0.05861756 457s [19] 0.02376374 0.49280484 0.00000000 0.49280484 0.00000000 0.05861756 457s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.02376374 457s [31] 0.25773527 0.00000000 0.25773527 -0.01991690 0.25773527 0.00000000 457s [37] 0.00000000 0.00000000 0.25773527 0.00000000 0.25773527 -0.01991690 457s [43] 0.25773527 0.02376374 0.05861756 -0.01991690 0.00000000 0.25773527 457s [49] 0.00000000 457s 457s $se.fit 457s [1] 0.19776187 0.00000000 0.13594191 0.00000000 0.13486241 0.00000000 457s [7] 0.13594191 0.00000000 0.13486241 0.13594191 0.13486241 0.09012454 457s [13] 0.13594191 0.09012454 0.13594191 0.13105561 0.13594191 0.13594191 457s [19] 0.13105561 0.19776187 0.00000000 0.19776187 0.00000000 0.13594191 457s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.13105561 457s [31] 0.13486241 0.00000000 0.13486241 0.09012454 0.13486241 0.00000000 457s [37] 0.00000000 0.00000000 0.13486241 0.00000000 0.13486241 0.09012454 457s [43] 0.13486241 0.13105561 0.13594191 0.09012454 0.00000000 0.13486241 457s [49] 0.00000000 457s 457s $fit 457s [1] -3.118383 -3.124477 -3.132746 457s 457s $se.fit 457s [1] 0.09194958 0.08435629 0.08409705 457s 457s $fit 457s 1 2 3 457s -3.118383 -3.124477 -3.132746 457s 457s $se.fit 457s 1 2 3 457s 0.09194958 0.08435629 0.08409705 457s 457s $df 457s [1] 46 457s 457s $residual.scale 457s [1] 0.4007027 457s 457s [1] 508.0679 457s [1] 62.95473 457s [1] 62.95473 457s Dose Response Model 457s 457s Model: quadratic 457s Fit-type: normal 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -0.87232 -0.24673 -0.00516 0.29930 0.65583 457s 457s Coefficients with approx. stand. error: 457s Estimate Std. Error 457s e0 -3.08e+00 1.69e-01 457s b1 -5.76e-04 1.59e-03 457s b2 4.82e-06 4.74e-06 457s age -1.60e-03 2.09e-03 457s centergreen -4.89e-03 2.03e-01 457s centerred 6.72e-02 1.75e-01 457s centersilver 7.81e-02 1.87e-01 457s centeryellow 9.70e-02 1.95e-01 457s 457s Residual standard error: 0.418 457s Degrees of freedom: 41 457s 457s Call: 457s lm(formula = y ~ x + I(x^2) + age + center, data = datset) 457s 457s Residuals: 457s Min 1Q Median 3Q Max 457s -0.65583 -0.29930 0.00516 0.24673 0.87232 457s 457s Coefficients: 457s Estimate Std. Error t value Pr(>|t|) 457s (Intercept) -3.076e+00 1.692e-01 -18.182 <2e-16 *** 457s x -5.756e-04 1.594e-03 -0.361 0.720 457s I(x^2) 4.822e-06 4.738e-06 1.018 0.315 457s age -1.604e-03 2.092e-03 -0.767 0.448 457s centergreen -4.891e-03 2.034e-01 -0.024 0.981 457s centerred 6.715e-02 1.753e-01 0.383 0.704 457s centersilver 7.814e-02 1.875e-01 0.417 0.679 457s centeryellow 9.700e-02 1.950e-01 0.497 0.622 457s --- 457s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 457s 457s Residual standard error: 0.4185 on 41 degrees of freedom 457s Multiple R-squared: 0.1437, Adjusted R-squared: -0.002451 457s F-statistic: 0.9832 on 7 and 41 DF, p-value: 0.4566 457s 457s e0 b1 b2 age 457s e0 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 457s b1 -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 457s b2 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 457s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 457s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 457s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 457s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 457s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 457s centergreen centerred centersilver centeryellow 457s e0 -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 457s b1 -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 457s b2 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 457s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 457s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 457s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 457s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 457s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 457s (Intercept) x I(x^2) age 457s (Intercept) 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 457s x -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 457s I(x^2) 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 457s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 457s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 457s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 457s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 457s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 457s centergreen centerred centersilver centeryellow 457s (Intercept) -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 457s x -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 457s I(x^2) 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 457s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 457s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 457s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 457s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 457s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 457s $fit 457s [1] -3.124527 -3.129801 -3.133870 457s 457s $se.fit 457s [1] 0.1418548 0.1377349 0.1475950 457s 457s $fit 457s 1 2 3 457s -3.124527 -3.129801 -3.133870 457s 457s $se.fit 457s 1 2 3 457s 0.1418548 0.1377349 0.1475950 457s 457s $df 457s [1] 41 457s 457s $residual.scale 457s [1] 0.418494 457s 457s [1] 215.5724 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457s [1] 0 0 0 0 0 457s [1] 0 0 0 0 0 457s Warning message: 457s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 457s mns is not a numeric but a array, converting with as.numeric() 457s Warning message: 457s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 457s mns is not a numeric but a array, converting with as.numeric() 457s e0 delta 457s 0.47569910 0.02447331 457s e0 delta 457s 0.47569910 0.02447331 457s Warning message: 457s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 457s mns is not a numeric but a array, converting with as.numeric() 457s Warning message: 457s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 457s mns is not a numeric but a array, converting with as.numeric() 457s testsFitting.R passed 457s Loading required package: DoseFinding 459s testsMCPMod.R passed 459s Loading required package: DoseFinding 459s Loading required package: multcomp 459s Loading required package: mvtnorm 459s Loading required package: survival 460s Loading required package: TH.data 460s Loading required package: MASS 460s 460s Attaching package: ‘TH.data’ 460s 460s The following object is masked from ‘package:MASS’: 460s 460s geyser 460s 460s 460s Simultaneous Tests for General Linear Hypotheses 460s 460s Multiple Comparisons of Means: User-defined Contrasts 460s 460s 460s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 460s 460s Linear Hypotheses: 460s Estimate Std. Error t value Pr(>t) 460s linear <= 0 0.07260 0.05755 1.262 0.1756 460s betaMod <= 0 0.12179 0.05559 2.191 0.0287 * 460s sigEmax <= 0 0.08677 0.05648 1.536 0.1114 460s --- 460s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 460s (Adjusted p values reported -- single-step method) 460s 460s Multiple Contrast Test 460s 460s Contrasts: 460s linear betaMod sigEmax 460s 0 -0.472 -0.492 -0.349 460s 172 -0.391 -0.345 -0.489 460s 285 -0.132 0.032 -0.240 460s 516 0.262 0.799 0.503 460s 761 0.733 0.007 0.574 460s 460s Contrast Correlation: 460s linear betaMod sigEmax 460s linear 1.000 0.645 0.942 460s betaMod 0.645 1.000 0.741 460s sigEmax 0.942 0.741 1.000 460s 460s Multiple Contrast Test: 460s t-Stat adj-p 460s betaMod 2.191 0.0287 460s sigEmax 1.536 0.1112 460s linear 1.262 0.1757 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: lm(formula = y ~ x, data = dd2) 461s 461s Linear Hypotheses: 461s Estimate Std. Error t value Pr(>t) 461s linear <= 0 0.07985 0.05691 1.403 0.1404 461s betaMod <= 0 0.11839 0.05507 2.150 0.0314 * 461s sigEmax <= 0 0.09407 0.05594 1.682 0.0853 . 461s --- 461s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linear betaMod sigEmax 461s 0 -0.472 -0.487 -0.347 461s 172 -0.389 -0.348 -0.490 461s 285 -0.132 0.030 -0.239 461s 516 0.255 0.800 0.500 461s 761 0.738 0.005 0.576 461s 461s Contrast Correlation: 461s linear betaMod sigEmax 461s linear 1.000 0.642 0.941 461s betaMod 0.642 1.000 0.740 461s sigEmax 0.941 0.740 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s betaMod 2.150 0.0317 461s sigEmax 1.682 0.0852 461s linear 1.403 0.1403 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 461s 461s Linear Hypotheses: 461s Estimate Std. Error t value Pr(>t) 461s linlog <= 0 0.09114 0.05971 1.526 0.1510 461s logistic1 <= 0 0.10293 0.05761 1.787 0.0940 . 461s logistic2 <= 0 0.09583 0.05707 1.679 0.1154 461s exponential <= 0 0.02544 0.05514 0.461 0.5623 461s quadratic <= 0 0.11676 0.05980 1.952 0.0674 . 461s --- 461s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linlog logistic1 logistic2 exponential quadratic 461s 0 -0.624 -0.448 -0.457 -0.268 -0.665 461s 172 -0.309 -0.590 -0.475 -0.347 -0.055 461s 285 -0.049 0.101 -0.118 -0.191 0.199 461s 516 0.366 0.500 0.499 -0.069 0.696 461s 761 0.616 0.437 0.550 0.875 -0.174 461s 461s Contrast Correlation: 461s linlog logistic1 logistic2 exponential quadratic 461s linlog 1.000 0.902 0.955 0.799 0.651 461s logistic1 0.902 1.000 0.949 0.671 0.660 461s logistic2 0.955 0.949 1.000 0.792 0.586 461s exponential 0.799 0.671 0.792 1.000 0.063 461s quadratic 0.651 0.660 0.586 0.063 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s quadratic 1.952 0.0675 461s logistic1 1.787 0.0941 461s logistic2 1.679 0.1154 461s linlog 1.526 0.1506 461s exponential 0.461 0.5625 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: lm(formula = y ~ x, data = dd2) 461s 461s Linear Hypotheses: 461s Estimate Std. Error t value Pr(>t) 461s linlog <= 0 0.09484 0.05913 1.604 0.1320 461s logistic1 <= 0 0.10608 0.05706 1.859 0.0817 . 461s logistic2 <= 0 0.10119 0.05654 1.790 0.0928 . 461s exponential <= 0 0.03666 0.05440 0.674 0.4665 461s quadratic <= 0 0.10792 0.05938 1.817 0.0885 . 461s --- 461s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linlog logistic1 logistic2 exponential quadratic 461s 0 -0.623 -0.445 -0.455 -0.270 -0.664 461s 172 -0.307 -0.592 -0.476 -0.342 -0.056 461s 285 -0.050 0.101 -0.118 -0.189 0.197 461s 516 0.358 0.497 0.496 -0.076 0.698 461s 761 0.622 0.440 0.554 0.877 -0.175 461s 461s Contrast Correlation: 461s linlog logistic1 logistic2 exponential quadratic 461s linlog 1.000 0.901 0.955 0.800 0.648 461s logistic1 0.901 1.000 0.949 0.670 0.658 461s logistic2 0.955 0.949 1.000 0.792 0.584 461s exponential 0.800 0.670 0.792 1.000 0.062 461s quadratic 0.648 0.658 0.584 0.062 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s logistic1 1.859 0.0816 461s quadratic 1.817 0.0887 461s logistic2 1.790 0.0933 461s linlog 1.604 0.1316 461s exponential 0.674 0.4667 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: lm(formula = y ~ x, data = dd2) 461s 461s Linear Hypotheses: 461s Estimate Std. Error t value Pr(>t) 461s linlog <= 0 -0.2995 1.0212 -0.293 0.821 461s logistic1 <= 0 -0.1795 0.9837 -0.182 0.785 461s logistic2 <= 0 -0.1401 0.9877 -0.142 0.771 461s exponential <= 0 -0.2892 0.9568 -0.302 0.823 461s quadratic <= 0 -0.1973 1.2830 -0.154 0.776 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linlog logistic1 logistic2 exponential quadratic 461s 0 -0.464 -0.268 -0.289 -0.207 -0.751 461s 124 -0.436 -0.627 -0.556 -0.450 -0.241 461s 272 0.013 -0.006 -0.083 -0.187 0.476 461s 560 0.127 0.196 0.172 -0.004 0.353 461s 865 0.761 0.705 0.755 0.848 0.164 461s 461s Contrast Correlation: 461s linlog logistic1 logistic2 exponential quadratic 461s linlog 1.000 0.950 0.963 0.890 0.665 461s logistic1 0.950 1.000 0.992 0.879 0.591 461s logistic2 0.963 0.992 1.000 0.922 0.542 461s exponential 0.890 0.879 0.922 1.000 0.252 461s quadratic 0.665 0.591 0.542 0.252 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s logistic2 -0.142 0.771 461s quadratic -0.154 0.776 461s logistic1 -0.182 0.785 461s linlog -0.293 0.821 461s exponential -0.302 0.823 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 461s 461s Linear Hypotheses: 461s Estimate Std. Error z value Pr(>z) 461s linear <= 0 0.19645 0.33561 0.585 0.395 461s betaMod <= 0 0.03813 0.31565 0.121 0.587 461s sigEmax <= 0 0.30472 0.34592 0.881 0.283 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linear betaMod sigEmax 461s 0 -0.794 -0.793 -0.774 461s 190 -0.064 -0.022 -0.192 461s 344 0.197 0.577 0.317 461s 404 0.098 0.190 0.163 461s 616 0.563 0.048 0.487 461s 461s Contrast Correlation: 461s linear betaMod sigEmax 461s linear 1.000 0.723 0.962 461s betaMod 0.723 1.000 0.793 461s sigEmax 0.962 0.793 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s sigEmax 0.881 0.283 461s linear 0.585 0.395 461s betaMod 0.121 0.587 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 461s 461s Linear Hypotheses: 461s Estimate Std. Error z value Pr(>z) 461s linear <= 0 0.2547 0.1877 1.357 0.1500 461s betaMod <= 0 0.2367 0.2371 0.999 0.2555 461s sigEmax <= 0 0.3698 0.1889 1.958 0.0476 * 461s --- 461s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linear betaMod sigEmax 461s 0 0.418 0.634 0.310 461s 68.5 0.114 0.150 0.139 461s 85.9 0.387 0.362 0.551 461s 166 0.027 -0.572 -0.033 461s 197 -0.015 -0.158 -0.054 461s 278 -0.129 -0.264 -0.172 461s 332 -0.803 -0.152 -0.740 461s 461s Contrast Correlation: 461s linear betaMod sigEmax 461s linear 1.000 0.635 0.967 461s betaMod 0.635 1.000 0.677 461s sigEmax 0.967 0.677 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s sigEmax 1.958 0.0477 461s linear 1.357 0.1501 461s betaMod 0.999 0.2556 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 461s 461s Linear Hypotheses: 461s Estimate Std. Error z value Pr(>z) 461s linear <= 0 0.3391 0.3218 1.054 0.226 461s betaMod <= 0 0.3556 0.3124 1.138 0.201 461s sigEmax <= 0 0.2935 0.3497 0.839 0.299 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linear betaMod sigEmax 461s 0 -0.721 -0.796 -0.547 461s 79.1 -0.129 -0.102 -0.312 461s 117 0.005 0.106 -0.137 461s 208 0.191 0.519 0.288 461s 398 0.654 0.274 0.708 461s 461s Contrast Correlation: 461s linear betaMod sigEmax 461s linear 1.000 0.785 0.954 461s betaMod 0.785 1.000 0.742 461s sigEmax 0.954 0.742 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s betaMod 1.138 0.201 461s linear 1.054 0.226 461s sigEmax 0.839 0.299 461s Warning message: 461s In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 461s Warning from mvtnorm::pmvt: univariate: using pnorm. 461s 461s Simultaneous Tests for General Linear Hypotheses 461s 461s Multiple Comparisons of Means: User-defined Contrasts 461s 461s 461s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 461s 461s Linear Hypotheses: 461s Estimate Std. Error z value Pr(>z) 461s linear <= 0 0.3391 0.3218 1.054 0.146 461s (Adjusted p values reported -- single-step method) 461s 461s Multiple Contrast Test 461s 461s Contrasts: 461s linear 461s 0 -0.721 461s 79.1 -0.129 461s 117 0.005 461s 208 0.191 461s 398 0.654 461s 461s Contrast Correlation: 461s linear 461s linear 1 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s linear 1.054 0.146 461s Dose Response Model 461s 461s Model: sigEmax 461s Fit-type: general 461s 461s Coefficients dose-response model 461s eMax ed50 h 461s 0.4714 0.4880 0.5000 461s 461s Fitted to: 461s 1 2 3 4 Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 461s 461s 0.2846 0.2965 0.3502 0.3480 461s 461s Generalized residual sum of squares: 0.07825 461s Multiple Contrast Test 461s 461s Contrasts: 461s emax linear logistic linInt 461s 1 0.462 -0.429 0.511 -0.672 461s 2 0.505 0.002 0.507 0.437 461s 3 0.504 0.400 0.485 0.418 461s 4 0.527 0.810 0.497 0.428 461s 461s Contrast Correlation: 461s emax linear logistic linInt 461s emax 1.000 0.715 1.000 0.617 461s linear 0.715 1.000 0.698 0.863 461s logistic 1.000 0.698 1.000 0.598 461s linInt 0.617 0.863 0.598 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s emax 3.178 0.00193 461s logistic 3.164 0.00194 461s linear 2.640 0.00968 461s linInt 2.247 0.02721 461s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 461s Dose Response Model 461s 461s Model: sigEmax 461s Fit-type: general 461s 461s Coefficients dose-response model 461s eMax ed50 h 461s 0.4714 0.4880 0.5000 461s 461s Fitted to: 461s 3 4 1 2 461s 0.3502 0.3480 0.2846 0.2965 461s 461s Generalized residual sum of squares: 0.07825 461s Multiple Contrast Test 461s 461s Contrasts: 461s emax linear logistic linInt 461s 1 0.462 -0.429 0.511 -0.672 461s 2 0.505 0.002 0.507 0.437 461s 3 0.504 0.400 0.485 0.418 461s 4 0.527 0.810 0.497 0.428 461s 461s Contrast Correlation: 461s emax linear logistic linInt 461s emax 1.000 0.715 1.000 0.617 461s linear 0.715 1.000 0.698 0.863 461s logistic 1.000 0.698 1.000 0.598 461s linInt 0.617 0.863 0.598 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s emax 3.178 0.00213 461s logistic 3.164 0.00174 461s linear 2.640 0.00941 461s linInt 2.247 0.02663 461s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 461s Dose Response Model 461s 461s Model: sigEmax 461s Fit-type: general 461s 461s Coefficients dose-response model 461s e0 eMax ed50 h 461s 0.2171 0.4714 0.4860 0.5000 461s 461s Fitted to: 461s 0 1 2 3 4 461s 0.2169 0.5016 0.5138 0.5677 0.5648 461s 461s Generalized residual sum of squares: 0.07892 461s Multiple Contrast Test 461s 461s Contrasts: 461s emax linear logistic linInt 461s 0 -0.894 -0.617 -0.894 -0.522 461s 1 0.207 -0.338 0.228 -0.573 461s 2 0.226 0.002 0.227 0.373 461s 3 0.227 0.315 0.218 0.358 461s 4 0.235 0.637 0.221 0.363 461s 461s Contrast Correlation: 461s emax linear logistic linInt 461s emax 1.000 0.715 1.000 0.618 461s linear 0.715 1.000 0.698 0.863 461s logistic 1.000 0.698 1.000 0.599 461s linInt 0.618 0.863 0.599 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s emax 3.186 0.00184 461s logistic 3.172 0.00177 461s linear 2.645 0.00956 461s linInt 2.254 0.02649 461s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 461s Dose Response Model 461s 461s Model: sigEmax 461s Fit-type: general 461s 461s Coefficients dose-response model 461s e0 eMax ed50 h 461s 0.2171 0.4714 0.4860 0.5000 461s 461s Fitted to: 461s 2 3 0 1 4 461s 0.5138 0.5677 0.2169 0.5016 0.5648 461s 461s Generalized residual sum of squares: 0.07892 461s Multiple Contrast Test 461s 461s Contrasts: 461s emax linear logistic linInt 461s 0 -0.894 -0.617 -0.894 -0.522 461s 1 0.207 -0.338 0.228 -0.573 461s 2 0.226 0.002 0.227 0.373 461s 3 0.227 0.315 0.218 0.358 461s 4 0.235 0.637 0.221 0.363 461s 461s Contrast Correlation: 461s emax linear logistic linInt 461s emax 1.000 0.715 1.000 0.618 461s linear 0.715 1.000 0.698 0.863 461s logistic 1.000 0.698 1.000 0.599 461s linInt 0.618 0.863 0.599 1.000 461s 461s Multiple Contrast Test: 461s t-Stat adj-p 461s emax 3.186 0.00163 461s logistic 3.172 0.00192 461s linear 2.645 0.00981 461s linInt 2.254 0.02699 461s [1] TRUE 461s Warning messages: 461s 1: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 461s Warning from mvtnorm::pmvt: Covariance matrix not positive semidefinite. 461s 2: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 461s Setting calculated p-value to NA 461s testsMCT.R passed 461s Loading required package: DoseFinding 462s Loading required package: quadprog 462s Loading required package: Rsolnp 462s testsoptContr.R passed 462s testsplotDRMod.R consists only from comments and returns non-zero exit value ... ignored 462s testssampSize.R passed 462s Loading required package: DoseFinding 463s [1] 0.3076509 463s [1] 0.6153019 463s [1] 0.9229528 463s [1] 2.673503 463s [1] 0.7028559 463s [1] 2.064397 463s [1] NA 464s testssamplMod.R passed 465s /usr/bin/xdg-open: 1032: www-browser: not found 465s /usr/bin/xdg-open: 1032: links2: not found 465s /usr/bin/xdg-open: 1032: elinks: not found 465s /usr/bin/xdg-open: 1032: links: not found 465s /usr/bin/xdg-open: 1032: lynx: not found 465s /usr/bin/xdg-open: 1032: w3m: not found 465s xdg-open: no method available for opening 'https://huisophiesunrshiny.shinyapps.io/designmcpmod/' 465s [ FAIL 0 | WARN 0 | SKIP 0 | PASS 53 ] 465s testthat.R passed 466s autopkgtest [23:47:03]: test run-unit-test: -----------------------] 466s autopkgtest [23:47:03]: test run-unit-test: - - - - - - - - - - results - - - - - - - - - - 466s run-unit-test PASS 467s autopkgtest [23:47:04]: test pkg-r-autopkgtest: preparing testbed 467s Reading package lists... 467s Building dependency tree... 467s Reading state information... 467s Solving dependencies... 468s The following NEW packages will be installed: 468s build-essential cpp cpp-15 cpp-15-aarch64-linux-gnu cpp-aarch64-linux-gnu 468s dctrl-tools g++ g++-15 g++-15-aarch64-linux-gnu g++-aarch64-linux-gnu gcc 468s gcc-15 gcc-15-aarch64-linux-gnu gcc-aarch64-linux-gnu gfortran gfortran-15 468s gfortran-15-aarch64-linux-gnu gfortran-aarch64-linux-gnu icu-devtools 468s libasan8 libblas-dev libbz2-dev libc-dev-bin libc6-dev libcc1-0 libcrypt-dev 468s libdeflate-dev libgcc-15-dev libgfortran-15-dev libhwasan0 libicu-dev 468s libisl23 libitm1 libjpeg-dev libjpeg-turbo8-dev libjpeg8-dev liblapack-dev 468s liblsan0 liblzma-dev libmpc3 libncurses-dev libpcre2-16-0 libpcre2-32-0 468s libpcre2-dev libpcre2-posix3 libpkgconf3 libpng-dev libreadline-dev 468s libstdc++-15-dev libtirpc-dev libtsan2 libubsan1 libzstd-dev linux-libc-dev 468s pkg-r-autopkgtest pkgconf pkgconf-bin r-base-dev rpcsvc-proto zlib1g-dev 468s 0 upgraded, 60 newly installed, 0 to remove and 0 not upgraded. 468s Need to get 103 MB of archives. 468s After this operation, 377 MB of additional disk space will be used. 468s Get:1 http://ftpmaster.internal/ubuntu resolute/main arm64 libc-dev-bin arm64 2.42-2ubuntu4 [22.5 kB] 468s Get:2 http://ftpmaster.internal/ubuntu resolute/main arm64 linux-libc-dev arm64 6.19.0-3.3 [1819 kB] 472s Get:3 http://ftpmaster.internal/ubuntu resolute/main arm64 libcrypt-dev arm64 1:4.5.1-1 [123 kB] 472s Get:4 http://ftpmaster.internal/ubuntu resolute/main arm64 rpcsvc-proto arm64 1.4.3-1build1 [65.6 kB] 472s Get:5 http://ftpmaster.internal/ubuntu resolute/main arm64 libc6-dev arm64 2.42-2ubuntu4 [1765 kB] 476s Get:6 http://ftpmaster.internal/ubuntu resolute/main arm64 libisl23 arm64 0.27-1build1 [676 kB] 478s Get:7 http://ftpmaster.internal/ubuntu resolute/main arm64 libmpc3 arm64 1.3.1-2 [55.6 kB] 478s Get:8 http://ftpmaster.internal/ubuntu resolute/main arm64 cpp-15-aarch64-linux-gnu arm64 15.2.0-12ubuntu1 [11.7 MB] 503s Get:9 http://ftpmaster.internal/ubuntu resolute/main arm64 cpp-15 arm64 15.2.0-12ubuntu1 [1030 B] 503s Get:10 http://ftpmaster.internal/ubuntu resolute/main arm64 cpp-aarch64-linux-gnu arm64 4:15.2.0-4ubuntu1 [5736 B] 503s Get:11 http://ftpmaster.internal/ubuntu resolute/main arm64 cpp arm64 4:15.2.0-4ubuntu1 [22.4 kB] 503s Get:12 http://ftpmaster.internal/ubuntu resolute/main arm64 libcc1-0 arm64 15.2.0-12ubuntu1 [49.0 kB] 503s Get:13 http://ftpmaster.internal/ubuntu resolute/main arm64 libitm1 arm64 15.2.0-12ubuntu1 [27.8 kB] 503s Get:14 http://ftpmaster.internal/ubuntu resolute/main arm64 libasan8 arm64 15.2.0-12ubuntu1 [2920 kB] 509s Get:15 http://ftpmaster.internal/ubuntu resolute/main arm64 liblsan0 arm64 15.2.0-12ubuntu1 [1316 kB] 513s Get:16 http://ftpmaster.internal/ubuntu resolute/main arm64 libtsan2 arm64 15.2.0-12ubuntu1 [2688 kB] 522s Get:17 http://ftpmaster.internal/ubuntu resolute/main arm64 libubsan1 arm64 15.2.0-12ubuntu1 [1175 kB] 527s Get:18 http://ftpmaster.internal/ubuntu resolute/main arm64 libhwasan0 arm64 15.2.0-12ubuntu1 [1638 kB] 530s Get:19 http://ftpmaster.internal/ubuntu resolute/main arm64 libgcc-15-dev arm64 15.2.0-12ubuntu1 [2600 kB] 536s Get:20 http://ftpmaster.internal/ubuntu resolute/main arm64 gcc-15-aarch64-linux-gnu arm64 15.2.0-12ubuntu1 [23.1 MB] 585s Get:21 http://ftpmaster.internal/ubuntu resolute/main arm64 gcc-15 arm64 15.2.0-12ubuntu1 [519 kB] 585s Get:22 http://ftpmaster.internal/ubuntu resolute/main arm64 gcc-aarch64-linux-gnu arm64 4:15.2.0-4ubuntu1 [1206 B] 585s Get:23 http://ftpmaster.internal/ubuntu resolute/main arm64 gcc arm64 4:15.2.0-4ubuntu1 [5016 B] 585s Get:24 http://ftpmaster.internal/ubuntu resolute/main arm64 libstdc++-15-dev arm64 15.2.0-12ubuntu1 [2549 kB] 590s Get:25 http://ftpmaster.internal/ubuntu resolute/main arm64 g++-15-aarch64-linux-gnu arm64 15.2.0-12ubuntu1 [13.2 MB] 622s Get:26 http://ftpmaster.internal/ubuntu resolute/main arm64 g++-15 arm64 15.2.0-12ubuntu1 [25.3 kB] 622s Get:27 http://ftpmaster.internal/ubuntu resolute/main arm64 g++-aarch64-linux-gnu arm64 4:15.2.0-4ubuntu1 [956 B] 622s Get:28 http://ftpmaster.internal/ubuntu resolute/main arm64 g++ arm64 4:15.2.0-4ubuntu1 [1080 B] 623s Get:29 http://ftpmaster.internal/ubuntu resolute/main arm64 build-essential arm64 12.12ubuntu2 [5254 B] 623s Get:30 http://ftpmaster.internal/ubuntu resolute/main arm64 dctrl-tools arm64 2.24-3build4 [102 kB] 623s Get:31 http://ftpmaster.internal/ubuntu resolute/main arm64 libgfortran-15-dev arm64 15.2.0-12ubuntu1 [490 kB] 623s Get:32 http://ftpmaster.internal/ubuntu resolute/main arm64 gfortran-15-aarch64-linux-gnu arm64 15.2.0-12ubuntu1 [12.5 MB] 650s Get:33 http://ftpmaster.internal/ubuntu resolute/main arm64 gfortran-15 arm64 15.2.0-12ubuntu1 [18.1 kB] 650s Get:34 http://ftpmaster.internal/ubuntu resolute/main arm64 gfortran-aarch64-linux-gnu arm64 4:15.2.0-4ubuntu1 [1022 B] 650s Get:35 http://ftpmaster.internal/ubuntu resolute/main arm64 gfortran arm64 4:15.2.0-4ubuntu1 [1160 B] 650s Get:36 http://ftpmaster.internal/ubuntu resolute/main arm64 icu-devtools arm64 78.2-1ubuntu1 [207 kB] 650s Get:37 http://ftpmaster.internal/ubuntu resolute/main arm64 libblas-dev arm64 3.12.1-7ubuntu1 [160 kB] 650s Get:38 http://ftpmaster.internal/ubuntu resolute/main arm64 libbz2-dev arm64 1.0.8-6build2 [34.9 kB] 650s Get:39 http://ftpmaster.internal/ubuntu resolute/main arm64 libdeflate-dev arm64 1.23-2build1 [54.3 kB] 651s Get:40 http://ftpmaster.internal/ubuntu resolute/main arm64 libicu-dev arm64 78.2-1ubuntu1 [12.5 MB] 677s Get:41 http://ftpmaster.internal/ubuntu resolute/main arm64 libjpeg-turbo8-dev arm64 2.1.5-4ubuntu3 [301 kB] 677s Get:42 http://ftpmaster.internal/ubuntu resolute/main arm64 libjpeg8-dev arm64 8c-2ubuntu11 [1484 B] 677s Get:43 http://ftpmaster.internal/ubuntu resolute/main arm64 libjpeg-dev arm64 8c-2ubuntu11 [1482 B] 677s Get:44 http://ftpmaster.internal/ubuntu resolute/main arm64 liblapack-dev arm64 3.12.1-7ubuntu1 [4456 kB] 696s Get:45 http://ftpmaster.internal/ubuntu resolute/main arm64 libncurses-dev arm64 6.6+20251231-1 [391 kB] 696s Get:46 http://ftpmaster.internal/ubuntu resolute/main arm64 libpcre2-16-0 arm64 10.46-1 [225 kB] 696s Get:47 http://ftpmaster.internal/ubuntu resolute/main arm64 libpcre2-32-0 arm64 10.46-1 [213 kB] 696s Get:48 http://ftpmaster.internal/ubuntu resolute/main arm64 libpcre2-posix3 arm64 10.46-1 [7300 B] 696s Get:49 http://ftpmaster.internal/ubuntu resolute/main arm64 libpcre2-dev arm64 10.46-1 [772 kB] 698s Get:50 http://ftpmaster.internal/ubuntu resolute/main arm64 libpkgconf3 arm64 1.8.1-4build1 [33.7 kB] 698s Get:51 http://ftpmaster.internal/ubuntu resolute/main arm64 zlib1g-dev arm64 1:1.3.dfsg+really1.3.1-1ubuntu2 [899 kB] 700s Get:52 http://ftpmaster.internal/ubuntu resolute/main arm64 libpng-dev arm64 1.6.54-1 [268 kB] 700s Get:53 http://ftpmaster.internal/ubuntu resolute/main arm64 libreadline-dev arm64 8.3-3 [199 kB] 700s Get:54 http://ftpmaster.internal/ubuntu resolute/main arm64 libzstd-dev arm64 1.5.7+dfsg-3 [349 kB] 700s Get:55 http://ftpmaster.internal/ubuntu resolute/main arm64 liblzma-dev arm64 5.8.2-2 [180 kB] 700s Get:56 http://ftpmaster.internal/ubuntu resolute/main arm64 pkgconf-bin arm64 1.8.1-4build1 [21.7 kB] 700s Get:57 http://ftpmaster.internal/ubuntu resolute/main arm64 pkgconf arm64 1.8.1-4build1 [16.8 kB] 700s Get:58 http://ftpmaster.internal/ubuntu resolute/main arm64 libtirpc-dev arm64 1.3.6+ds-1 [202 kB] 700s Get:59 http://ftpmaster.internal/ubuntu resolute/universe arm64 r-base-dev all 4.5.2-1ubuntu2 [1880 B] 700s Get:60 http://ftpmaster.internal/ubuntu resolute/universe arm64 pkg-r-autopkgtest all 20250812 [6158 B] 700s Fetched 103 MB in 3min 52s (443 kB/s) 700s Selecting previously unselected package libc-dev-bin. 700s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 154018 files and directories currently installed.) 700s Preparing to unpack .../00-libc-dev-bin_2.42-2ubuntu4_arm64.deb ... 700s Unpacking libc-dev-bin (2.42-2ubuntu4) ... 700s Selecting previously unselected package linux-libc-dev:arm64. 700s Preparing to unpack .../01-linux-libc-dev_6.19.0-3.3_arm64.deb ... 700s Unpacking linux-libc-dev:arm64 (6.19.0-3.3) ... 700s Selecting previously unselected package libcrypt-dev:arm64. 700s Preparing to unpack .../02-libcrypt-dev_1%3a4.5.1-1_arm64.deb ... 700s Unpacking libcrypt-dev:arm64 (1:4.5.1-1) ... 700s Selecting previously unselected package rpcsvc-proto. 700s Preparing to unpack .../03-rpcsvc-proto_1.4.3-1build1_arm64.deb ... 700s Unpacking rpcsvc-proto (1.4.3-1build1) ... 700s Selecting previously unselected package libc6-dev:arm64. 700s Preparing to unpack .../04-libc6-dev_2.42-2ubuntu4_arm64.deb ... 700s Unpacking libc6-dev:arm64 (2.42-2ubuntu4) ... 700s Selecting previously unselected package libisl23:arm64. 700s Preparing to unpack .../05-libisl23_0.27-1build1_arm64.deb ... 700s Unpacking libisl23:arm64 (0.27-1build1) ... 700s Selecting previously unselected package libmpc3:arm64. 700s Preparing to unpack .../06-libmpc3_1.3.1-2_arm64.deb ... 700s Unpacking libmpc3:arm64 (1.3.1-2) ... 700s Selecting previously unselected package cpp-15-aarch64-linux-gnu. 701s Preparing to unpack .../07-cpp-15-aarch64-linux-gnu_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking cpp-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package cpp-15. 701s Preparing to unpack .../08-cpp-15_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking cpp-15 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package cpp-aarch64-linux-gnu. 701s Preparing to unpack .../09-cpp-aarch64-linux-gnu_4%3a15.2.0-4ubuntu1_arm64.deb ... 701s Unpacking cpp-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 701s Selecting previously unselected package cpp. 701s Preparing to unpack .../10-cpp_4%3a15.2.0-4ubuntu1_arm64.deb ... 701s Unpacking cpp (4:15.2.0-4ubuntu1) ... 701s Selecting previously unselected package libcc1-0:arm64. 701s Preparing to unpack .../11-libcc1-0_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libcc1-0:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libitm1:arm64. 701s Preparing to unpack .../12-libitm1_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libitm1:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libasan8:arm64. 701s Preparing to unpack .../13-libasan8_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libasan8:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package liblsan0:arm64. 701s Preparing to unpack .../14-liblsan0_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking liblsan0:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libtsan2:arm64. 701s Preparing to unpack .../15-libtsan2_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libtsan2:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libubsan1:arm64. 701s Preparing to unpack .../16-libubsan1_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libubsan1:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libhwasan0:arm64. 701s Preparing to unpack .../17-libhwasan0_15.2.0-12ubuntu1_arm64.deb ... 701s Unpacking libhwasan0:arm64 (15.2.0-12ubuntu1) ... 701s Selecting previously unselected package libgcc-15-dev:arm64. 701s Preparing to unpack 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.../23-libstdc++-15-dev_15.2.0-12ubuntu1_arm64.deb ... 702s Unpacking libstdc++-15-dev:arm64 (15.2.0-12ubuntu1) ... 702s Selecting previously unselected package g++-15-aarch64-linux-gnu. 702s Preparing to unpack .../24-g++-15-aarch64-linux-gnu_15.2.0-12ubuntu1_arm64.deb ... 702s Unpacking g++-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 702s Selecting previously unselected package g++-15. 702s Preparing to unpack .../25-g++-15_15.2.0-12ubuntu1_arm64.deb ... 702s Unpacking g++-15 (15.2.0-12ubuntu1) ... 702s Selecting previously unselected package g++-aarch64-linux-gnu. 702s Preparing to unpack .../26-g++-aarch64-linux-gnu_4%3a15.2.0-4ubuntu1_arm64.deb ... 702s Unpacking g++-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 702s Selecting previously unselected package g++. 702s Preparing to unpack .../27-g++_4%3a15.2.0-4ubuntu1_arm64.deb ... 702s Unpacking g++ (4:15.2.0-4ubuntu1) ... 703s Selecting previously unselected package build-essential. 703s Preparing to unpack .../28-build-essential_12.12ubuntu2_arm64.deb ... 703s Unpacking build-essential (12.12ubuntu2) ... 703s Selecting previously unselected package dctrl-tools. 703s Preparing to unpack .../29-dctrl-tools_2.24-3build4_arm64.deb ... 703s Unpacking dctrl-tools (2.24-3build4) ... 703s Selecting previously unselected package libgfortran-15-dev:arm64. 703s Preparing to unpack .../30-libgfortran-15-dev_15.2.0-12ubuntu1_arm64.deb ... 703s Unpacking libgfortran-15-dev:arm64 (15.2.0-12ubuntu1) ... 703s Selecting previously unselected package gfortran-15-aarch64-linux-gnu. 703s Preparing to unpack .../31-gfortran-15-aarch64-linux-gnu_15.2.0-12ubuntu1_arm64.deb ... 703s Unpacking gfortran-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 703s Selecting previously unselected package gfortran-15. 703s Preparing to unpack .../32-gfortran-15_15.2.0-12ubuntu1_arm64.deb ... 703s Unpacking gfortran-15 (15.2.0-12ubuntu1) ... 703s Selecting previously unselected package gfortran-aarch64-linux-gnu. 703s Preparing to unpack .../33-gfortran-aarch64-linux-gnu_4%3a15.2.0-4ubuntu1_arm64.deb ... 703s Unpacking gfortran-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 703s Selecting previously unselected package gfortran. 703s Preparing to unpack .../34-gfortran_4%3a15.2.0-4ubuntu1_arm64.deb ... 703s Unpacking gfortran (4:15.2.0-4ubuntu1) ... 703s Selecting previously unselected package icu-devtools. 703s Preparing to unpack .../35-icu-devtools_78.2-1ubuntu1_arm64.deb ... 703s Unpacking icu-devtools (78.2-1ubuntu1) ... 703s Selecting previously unselected package libblas-dev:arm64. 703s Preparing to unpack .../36-libblas-dev_3.12.1-7ubuntu1_arm64.deb ... 703s Unpacking libblas-dev:arm64 (3.12.1-7ubuntu1) ... 703s Selecting previously unselected package libbz2-dev:arm64. 703s Preparing to unpack .../37-libbz2-dev_1.0.8-6build2_arm64.deb ... 703s Unpacking libbz2-dev:arm64 (1.0.8-6build2) ... 703s Selecting previously unselected package libdeflate-dev:arm64. 703s Preparing to unpack .../38-libdeflate-dev_1.23-2build1_arm64.deb ... 703s Unpacking libdeflate-dev:arm64 (1.23-2build1) ... 703s Selecting previously unselected package libicu-dev:arm64. 703s Preparing to unpack .../39-libicu-dev_78.2-1ubuntu1_arm64.deb ... 703s Unpacking libicu-dev:arm64 (78.2-1ubuntu1) ... 704s Selecting previously unselected package libjpeg-turbo8-dev:arm64. 704s Preparing to unpack .../40-libjpeg-turbo8-dev_2.1.5-4ubuntu3_arm64.deb ... 704s Unpacking libjpeg-turbo8-dev:arm64 (2.1.5-4ubuntu3) ... 704s Selecting previously unselected package libjpeg8-dev:arm64. 704s Preparing to unpack .../41-libjpeg8-dev_8c-2ubuntu11_arm64.deb ... 704s Unpacking libjpeg8-dev:arm64 (8c-2ubuntu11) ... 704s Selecting previously unselected package libjpeg-dev:arm64. 704s Preparing to unpack .../42-libjpeg-dev_8c-2ubuntu11_arm64.deb ... 704s Unpacking libjpeg-dev:arm64 (8c-2ubuntu11) ... 704s Selecting previously unselected package liblapack-dev:arm64. 704s Preparing to unpack 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... 704s Selecting previously unselected package liblzma-dev:arm64. 704s Preparing to unpack .../54-liblzma-dev_5.8.2-2_arm64.deb ... 704s Unpacking liblzma-dev:arm64 (5.8.2-2) ... 704s Selecting previously unselected package pkgconf-bin. 704s Preparing to unpack .../55-pkgconf-bin_1.8.1-4build1_arm64.deb ... 704s Unpacking pkgconf-bin (1.8.1-4build1) ... 704s Selecting previously unselected package pkgconf:arm64. 704s Preparing to unpack .../56-pkgconf_1.8.1-4build1_arm64.deb ... 704s Unpacking pkgconf:arm64 (1.8.1-4build1) ... 704s Selecting previously unselected package libtirpc-dev:arm64. 704s Preparing to unpack .../57-libtirpc-dev_1.3.6+ds-1_arm64.deb ... 704s Unpacking libtirpc-dev:arm64 (1.3.6+ds-1) ... 705s Selecting previously unselected package r-base-dev. 705s Preparing to unpack .../58-r-base-dev_4.5.2-1ubuntu2_all.deb ... 705s Unpacking r-base-dev (4.5.2-1ubuntu2) ... 705s Selecting previously unselected package pkg-r-autopkgtest. 705s Preparing to unpack .../59-pkg-r-autopkgtest_20250812_all.deb ... 705s Unpacking pkg-r-autopkgtest (20250812) ... 705s Setting up libzstd-dev:arm64 (1.5.7+dfsg-3) ... 705s Setting up linux-libc-dev:arm64 (6.19.0-3.3) ... 705s Setting up libpcre2-16-0:arm64 (10.46-1) ... 705s Setting up libpcre2-32-0:arm64 (10.46-1) ... 705s Setting up libtirpc-dev:arm64 (1.3.6+ds-1) ... 705s Setting up libpkgconf3:arm64 (1.8.1-4build1) ... 705s Setting up rpcsvc-proto (1.4.3-1build1) ... 705s Setting up libmpc3:arm64 (1.3.1-2) ... 705s Setting up icu-devtools (78.2-1ubuntu1) ... 705s Setting up pkgconf-bin (1.8.1-4build1) ... 705s Setting up liblzma-dev:arm64 (5.8.2-2) ... 705s Setting up libubsan1:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libpcre2-posix3:arm64 (10.46-1) ... 705s Setting up libhwasan0:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libcrypt-dev:arm64 (1:4.5.1-1) ... 705s Setting up libasan8:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libtsan2:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libisl23:arm64 (0.27-1build1) ... 705s Setting up libc-dev-bin (2.42-2ubuntu4) ... 705s Setting up libdeflate-dev:arm64 (1.23-2build1) ... 705s Setting up libcc1-0:arm64 (15.2.0-12ubuntu1) ... 705s Setting up liblsan0:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libblas-dev:arm64 (3.12.1-7ubuntu1) ... 705s update-alternatives: using /usr/lib/aarch64-linux-gnu/blas/libblas.so to provide /usr/lib/aarch64-linux-gnu/libblas.so (libblas.so-aarch64-linux-gnu) in auto mode 705s Setting up dctrl-tools (2.24-3build4) ... 705s Setting up libitm1:arm64 (15.2.0-12ubuntu1) ... 705s Setting up cpp-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 705s Setting up libgcc-15-dev:arm64 (15.2.0-12ubuntu1) ... 705s Setting up libgfortran-15-dev:arm64 (15.2.0-12ubuntu1) ... 705s Setting up pkgconf:arm64 (1.8.1-4build1) ... 705s Setting up cpp-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 705s Setting up liblapack-dev:arm64 (3.12.1-7ubuntu1) ... 705s update-alternatives: using /usr/lib/aarch64-linux-gnu/lapack/liblapack.so to provide /usr/lib/aarch64-linux-gnu/liblapack.so (liblapack.so-aarch64-linux-gnu) in auto mode 705s Setting up cpp-15 (15.2.0-12ubuntu1) ... 705s Setting up cpp (4:15.2.0-4ubuntu1) ... 705s Setting up libc6-dev:arm64 (2.42-2ubuntu4) ... 705s Setting up libicu-dev:arm64 (78.2-1ubuntu1) ... 705s Setting up libbz2-dev:arm64 (1.0.8-6build2) ... 705s Setting up libjpeg-turbo8-dev:arm64 (2.1.5-4ubuntu3) ... 705s Setting up libncurses-dev:arm64 (6.6+20251231-1) ... 705s Setting up gcc-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 705s Setting up libpcre2-dev:arm64 (10.46-1) ... 705s Setting up libreadline-dev:arm64 (8.3-3) ... 705s Setting up gcc-15 (15.2.0-12ubuntu1) ... 705s Setting up libstdc++-15-dev:arm64 (15.2.0-12ubuntu1) ... 705s Setting up gfortran-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 705s Setting up g++-15-aarch64-linux-gnu (15.2.0-12ubuntu1) ... 705s Setting up zlib1g-dev:arm64 (1:1.3.dfsg+really1.3.1-1ubuntu2) ... 705s Setting up libjpeg8-dev:arm64 (8c-2ubuntu11) ... 705s Setting up g++-15 (15.2.0-12ubuntu1) ... 705s Setting up gfortran-15 (15.2.0-12ubuntu1) ... 705s Setting up gcc-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 705s Setting up libpng-dev:arm64 (1.6.54-1) ... 705s Setting up libjpeg-dev:arm64 (8c-2ubuntu11) ... 705s Setting up gcc (4:15.2.0-4ubuntu1) ... 705s Setting up g++-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 705s Setting up gfortran-aarch64-linux-gnu (4:15.2.0-4ubuntu1) ... 705s Setting up gfortran (4:15.2.0-4ubuntu1) ... 705s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f95 (f95) in auto mode 705s update-alternatives: warning: skip creation of /usr/share/man/man1/f95.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f95) doesn't exist 705s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f77 (f77) in auto mode 705s update-alternatives: warning: skip creation of /usr/share/man/man1/f77.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f77) doesn't exist 705s Setting up g++ (4:15.2.0-4ubuntu1) ... 705s update-alternatives: using /usr/bin/g++ to provide /usr/bin/c++ (c++) in auto mode 705s Setting up build-essential (12.12ubuntu2) ... 705s Setting up r-base-dev (4.5.2-1ubuntu2) ... 705s Setting up pkg-r-autopkgtest (20250812) ... 705s Processing triggers for libc-bin (2.42-2ubuntu4) ... 705s Processing triggers for man-db (2.13.1-1build1) ... 706s Processing triggers for install-info (7.2-5) ... 707s autopkgtest [23:51:04]: test pkg-r-autopkgtest: /usr/share/dh-r/pkg-r-autopkgtest 707s autopkgtest [23:51:04]: test pkg-r-autopkgtest: [----------------------- 707s Test: Try to load the R library DoseFinding 707s 707s R version 4.5.2 (2025-10-31) -- "[Not] Part in a Rumble" 707s Copyright (C) 2025 The R Foundation for Statistical Computing 707s Platform: aarch64-unknown-linux-gnu 707s 707s R is free software and comes with ABSOLUTELY NO WARRANTY. 707s You are welcome to redistribute it under certain conditions. 707s Type 'license()' or 'licence()' for distribution details. 707s 707s R is a collaborative project with many contributors. 707s Type 'contributors()' for more information and 707s 'citation()' on how to cite R or R packages in publications. 707s 707s Type 'demo()' for some demos, 'help()' for on-line help, or 707s 'help.start()' for an HTML browser interface to help. 707s Type 'q()' to quit R. 707s 708s > library('DoseFinding') 708s autopkgtest [23:51:05]: test pkg-r-autopkgtest: -----------------------] 708s > 709s pkg-r-autopkgtest PASS 709s autopkgtest [23:51:06]: test pkg-r-autopkgtest: - - - - - - - - - - results - - - - - - - - - - 709s autopkgtest [23:51:06]: @@@@@@@@@@@@@@@@@@@@ summary 709s run-unit-test PASS 709s pkg-r-autopkgtest PASS