0s autopkgtest [23:25:30]: starting date and time: 2026-02-09 23:25:30+0000 0s autopkgtest [23:25:30]: git checkout: 4b346b80 nova: make wait_reboot return success even when a no-op 0s autopkgtest [23:25:30]: host juju-7f2275-prod-proposed-migration-environment-2; command line: /home/ubuntu/autopkgtest/runner/autopkgtest --output-dir /tmp/autopkgtest-work.y3_bf73o/out --timeout-copy=6000 --needs-internet=try --setup-commands /home/ubuntu/autopkgtest-cloud/worker-config-production/setup-canonical.sh --apt-pocket=proposed=src:lattice --apt-upgrade r-cran-dosefinding --timeout-short=300 --timeout-copy=20000 --timeout-build=20000 --env=ADT_TEST_TRIGGERS=lattice/0.22-9-1 -- ssh -s /home/ubuntu/autopkgtest/ssh-setup/nova -- --flavor autopkgtest-cpu2-ram4-disk20-amd64 --security-groups autopkgtest-juju-7f2275-prod-proposed-migration-environment-2@sto01-10.secgroup --name adt-resolute-amd64-r-cran-dosefinding-20260209-232530-juju-7f2275-prod-proposed-migration-environment-2-a123a495-2f3c-41a2-ad5d-84deaf0a2f55 --image adt/ubuntu-resolute-amd64-server --keyname testbed-juju-7f2275-prod-proposed-migration-environment-2 --net-id=net_prod-autopkgtest-workers-amd64 -e TERM=linux --mirror=http://ftpmaster.internal/ubuntu/ 4s Creating nova instance adt-resolute-amd64-r-cran-dosefinding-20260209-232530-juju-7f2275-prod-proposed-migration-environment-2-a123a495-2f3c-41a2-ad5d-84deaf0a2f55 from image adt/ubuntu-resolute-amd64-server-20260204.img (UUID fedf54b4-458b-493e-8072-6425c19717b4)... 177s autopkgtest [23:28:27]: testbed dpkg architecture: amd64 177s autopkgtest [23:28:27]: testbed apt version: 3.1.14 177s autopkgtest [23:28:27]: @@@@@@@@@@@@@@@@@@@@ test bed setup 177s autopkgtest [23:28:27]: testbed release detected to be: None 178s autopkgtest [23:28:28]: updating testbed package index (apt update) 178s Get:1 http://ftpmaster.internal/ubuntu resolute-proposed InRelease [124 kB] 178s Hit:2 http://ftpmaster.internal/ubuntu resolute InRelease 178s Hit:3 http://ftpmaster.internal/ubuntu resolute-updates InRelease 178s Hit:4 http://ftpmaster.internal/ubuntu resolute-security InRelease 178s Get:5 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse Sources [29.4 kB] 178s Get:6 http://ftpmaster.internal/ubuntu resolute-proposed/main Sources [176 kB] 178s Get:7 http://ftpmaster.internal/ubuntu resolute-proposed/universe Sources [1645 kB] 181s Get:8 http://ftpmaster.internal/ubuntu resolute-proposed/main amd64 Packages [249 kB] 181s Get:9 http://ftpmaster.internal/ubuntu resolute-proposed/main i386 Packages [210 kB] 182s Get:10 http://ftpmaster.internal/ubuntu resolute-proposed/main amd64 c-n-f Metadata [5980 B] 182s Get:11 http://ftpmaster.internal/ubuntu resolute-proposed/restricted amd64 c-n-f Metadata [316 B] 182s Get:12 http://ftpmaster.internal/ubuntu resolute-proposed/universe i386 Packages [657 kB] 183s Get:13 http://ftpmaster.internal/ubuntu resolute-proposed/universe amd64 Packages [1592 kB] 186s Get:14 http://ftpmaster.internal/ubuntu resolute-proposed/universe amd64 c-n-f Metadata [33.1 kB] 186s Get:15 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse amd64 Packages [25.2 kB] 186s Get:16 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse i386 Packages [4320 B] 186s Get:17 http://ftpmaster.internal/ubuntu resolute-proposed/multiverse amd64 c-n-f Metadata [996 B] 186s Fetched 4752 kB in 8s (613 kB/s) 187s Reading package lists... 187s Hit:1 http://ftpmaster.internal/ubuntu resolute-proposed InRelease 187s Hit:2 http://ftpmaster.internal/ubuntu resolute InRelease 187s Hit:3 http://ftpmaster.internal/ubuntu resolute-updates InRelease 187s Hit:4 http://ftpmaster.internal/ubuntu resolute-security InRelease 188s Reading package lists... 188s Reading package lists... 188s Building dependency tree... 188s Reading state information... 188s Calculating upgrade... 188s The following package was automatically installed and is no longer required: 188s libpython3.13 188s Use 'sudo apt autoremove' to remove it. 188s The following NEW packages will be installed: 188s libpython3.14 libpython3.14-minimal libpython3.14-stdlib 188s linux-headers-6.19.0-3 linux-headers-6.19.0-3-generic 188s linux-image-6.19.0-3-generic linux-modules-6.19.0-3-generic 188s linux-tools-6.19.0-3 linux-tools-6.19.0-3-generic 188s The following packages will be upgraded: 188s 3cpio amd64-microcode apt bpftool busybox-initramfs busybox-static 188s cryptsetup-bin dash dbus dbus-bin dbus-daemon dbus-session-bus-common 188s dbus-system-bus-common dbus-user-session debianutils dmsetup dracut-install 188s ethtool findutils gir1.2-girepository-3.0 gir1.2-glib-2.0 hwdata iproute2 188s iptables less libapt-pkg7.0 libattr1 libbpf1 libbsd0 libcryptsetup12 188s libdbus-1-3 libdevmapper1.02.1 libdrm-amdgpu1 libdrm-common libdrm2 188s libevent-core-2.1-7t64 libgdbm-compat4t64 libgdbm6t64 libgirepository-2.0-0 188s libglib2.0-0t64 libglib2.0-data libgpm2 libgudev-1.0-0 libidn2-0 libip4tc2 188s libip6tc2 libjansson4 libkeyutils1 liblsof0 libmaxminddb0 188s libnetfilter-conntrack3 libnpth0t64 libonig5 libpcap0.8t64 libpci3 188s libsensors-config libsensors5 libusb-1.0-0 libwrap0 libxau6 libxkbcommon0 188s libxtables12 linux-generic linux-headers-generic linux-headers-virtual 188s linux-image-generic linux-image-virtual linux-perf linux-tools-common 188s linux-virtual lsof man-db mawk patch pciutils pnp.ids pollinate 188s python3-linkify-it python3-markdown-it python3-referencing sed 188s shared-mime-info tar tcpdump ubuntu-kernel-accessories ubuntu-standard wget 188s 87 upgraded, 9 newly installed, 0 to remove and 0 not upgraded. 188s Need to get 236 MB of archives. 188s After this operation, 339 MB of additional disk space will be used. 188s Get:1 http://ftpmaster.internal/ubuntu resolute/main amd64 debianutils amd64 5.23.2build1 [93.3 kB] 188s Get:2 http://ftpmaster.internal/ubuntu resolute/main amd64 dash amd64 0.5.12-12ubuntu3 [96.0 kB] 188s Get:3 http://ftpmaster.internal/ubuntu resolute/main amd64 findutils amd64 4.10.0-3build2 [307 kB] 188s Get:4 http://ftpmaster.internal/ubuntu resolute/main amd64 sed amd64 4.9-2build3 [195 kB] 188s Get:5 http://ftpmaster.internal/ubuntu resolute/main amd64 tar amd64 1.35+dfsg-3.1build2 [257 kB] 188s Get:6 http://ftpmaster.internal/ubuntu resolute/main amd64 libattr1 amd64 1:2.5.2-3build2 [11.4 kB] 188s Get:7 http://ftpmaster.internal/ubuntu resolute/main amd64 libbsd0 amd64 0.12.2-2build2 [42.3 kB] 188s Get:8 http://ftpmaster.internal/ubuntu resolute/main amd64 mawk amd64 1.3.4.20260129-1 [133 kB] 188s Get:9 http://ftpmaster.internal/ubuntu resolute/main amd64 libapt-pkg7.0 amd64 3.1.15 [1151 kB] 191s Get:10 http://ftpmaster.internal/ubuntu resolute/main amd64 apt amd64 3.1.15 [1479 kB] 193s Get:11 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus-system-bus-common all 1.16.2-2ubuntu3 [55.8 kB] 193s Get:12 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus-session-bus-common all 1.16.2-2ubuntu3 [54.4 kB] 193s Get:13 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus-user-session amd64 1.16.2-2ubuntu3 [9696 B] 193s Get:14 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus-daemon amd64 1.16.2-2ubuntu3 [119 kB] 193s Get:15 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus-bin amd64 1.16.2-2ubuntu3 [40.1 kB] 193s Get:16 http://ftpmaster.internal/ubuntu resolute/main amd64 dbus amd64 1.16.2-2ubuntu3 [24.2 kB] 193s Get:17 http://ftpmaster.internal/ubuntu resolute/main amd64 libdbus-1-3 amd64 1.16.2-2ubuntu3 [185 kB] 193s Get:18 http://ftpmaster.internal/ubuntu resolute/main amd64 libdevmapper1.02.1 amd64 2:1.02.205-2ubuntu3 [142 kB] 193s Get:19 http://ftpmaster.internal/ubuntu resolute/main amd64 dmsetup amd64 2:1.02.205-2ubuntu3 [79.4 kB] 193s Get:20 http://ftpmaster.internal/ubuntu resolute/main amd64 ethtool amd64 1:6.15-3build1 [318 kB] 193s Get:21 http://ftpmaster.internal/ubuntu resolute/main amd64 gir1.2-girepository-3.0 amd64 2.87.2-2 [25.2 kB] 193s Get:22 http://ftpmaster.internal/ubuntu resolute/main amd64 libgirepository-2.0-0 amd64 2.87.2-2 [76.1 kB] 193s Get:23 http://ftpmaster.internal/ubuntu resolute/main amd64 gir1.2-glib-2.0 amd64 2.87.2-2 [182 kB] 193s Get:24 http://ftpmaster.internal/ubuntu resolute/main amd64 libglib2.0-0t64 amd64 2.87.2-2 [1613 kB] 196s Get:25 http://ftpmaster.internal/ubuntu resolute/main amd64 libbpf1 amd64 1:1.6.2-1build1 [184 kB] 196s Get:26 http://ftpmaster.internal/ubuntu resolute/main amd64 iptables amd64 1.8.11-2ubuntu3 [381 kB] 196s Get:27 http://ftpmaster.internal/ubuntu resolute/main amd64 libip4tc2 amd64 1.8.11-2ubuntu3 [24.2 kB] 196s Get:28 http://ftpmaster.internal/ubuntu resolute/main amd64 libip6tc2 amd64 1.8.11-2ubuntu3 [24.4 kB] 196s Get:29 http://ftpmaster.internal/ubuntu resolute/main amd64 libnetfilter-conntrack3 amd64 1.1.1-1 [47.5 kB] 196s Get:30 http://ftpmaster.internal/ubuntu resolute/main amd64 libxtables12 amd64 1.8.11-2ubuntu3 [36.6 kB] 196s Get:31 http://ftpmaster.internal/ubuntu resolute/main amd64 iproute2 amd64 6.18.0-1ubuntu1 [1178 kB] 198s Get:32 http://ftpmaster.internal/ubuntu resolute/main amd64 less amd64 668-1build1 [172 kB] 198s Get:33 http://ftpmaster.internal/ubuntu resolute/main amd64 libcryptsetup12 amd64 2:2.8.0-1ubuntu3 [283 kB] 198s Get:34 http://ftpmaster.internal/ubuntu resolute/main amd64 libglib2.0-data all 2.87.2-2 [58.2 kB] 198s Get:35 http://ftpmaster.internal/ubuntu resolute/main amd64 libidn2-0 amd64 2.3.8-4build1 [67.6 kB] 198s Get:36 http://ftpmaster.internal/ubuntu resolute/main amd64 libkeyutils1 amd64 1.6.3-6ubuntu3 [10.6 kB] 198s Get:37 http://ftpmaster.internal/ubuntu resolute/main amd64 python3-linkify-it all 2.0.3-1ubuntu3 [19.4 kB] 198s Get:38 http://ftpmaster.internal/ubuntu resolute/main amd64 python3-markdown-it all 3.0.0-3build1 [54.4 kB] 198s Get:39 http://ftpmaster.internal/ubuntu resolute/main amd64 shared-mime-info amd64 2.4-5build3 [476 kB] 198s Get:40 http://ftpmaster.internal/ubuntu resolute/main amd64 busybox-static amd64 1:1.37.0-7ubuntu1 [1034 kB] 199s Get:41 http://ftpmaster.internal/ubuntu resolute/main amd64 libdrm-common all 2.4.131-1 [9774 B] 199s Get:42 http://ftpmaster.internal/ubuntu resolute/main amd64 libdrm2 amd64 2.4.131-1 [42.3 kB] 199s Get:43 http://ftpmaster.internal/ubuntu resolute/main amd64 libgdbm6t64 amd64 1.26-1build1 [36.5 kB] 199s Get:44 http://ftpmaster.internal/ubuntu resolute/main amd64 libgpm2 amd64 1.20.7-12build1 [14.4 kB] 199s Get:45 http://ftpmaster.internal/ubuntu resolute/main amd64 libjansson4 amd64 2.14-2build4 [33.2 kB] 199s Get:46 http://ftpmaster.internal/ubuntu resolute/main amd64 lsof amd64 4.99.4+dfsg-2build2 [239 kB] 199s Get:47 http://ftpmaster.internal/ubuntu resolute/main amd64 liblsof0 amd64 4.99.4+dfsg-2build2 [56.5 kB] 199s Get:48 http://ftpmaster.internal/ubuntu resolute/main amd64 libmaxminddb0 amd64 1.12.2-1build2 [18.9 kB] 199s Get:49 http://ftpmaster.internal/ubuntu resolute/main amd64 libpcap0.8t64 amd64 1.10.5-2ubuntu3 [154 kB] 199s Get:50 http://ftpmaster.internal/ubuntu resolute/main amd64 pciutils amd64 1:3.14.0-1build2 [95.5 kB] 199s Get:51 http://ftpmaster.internal/ubuntu resolute/main amd64 libpci3 amd64 1:3.14.0-1build2 [38.1 kB] 199s Get:52 http://ftpmaster.internal/ubuntu resolute/main amd64 libsensors-config all 1:3.6.2-2build1 [6862 B] 199s Get:53 http://ftpmaster.internal/ubuntu resolute/main amd64 libsensors5 amd64 1:3.6.2-2build1 [28.9 kB] 199s Get:54 http://ftpmaster.internal/ubuntu resolute/main amd64 libusb-1.0-0 amd64 2:1.0.29-2build1 [56.9 kB] 199s Get:55 http://ftpmaster.internal/ubuntu resolute/main amd64 libxau6 amd64 1:1.0.11-1build2 [7502 B] 199s Get:56 http://ftpmaster.internal/ubuntu resolute/main amd64 libxkbcommon0 amd64 1.13.1-1 [159 kB] 199s Get:57 http://ftpmaster.internal/ubuntu resolute/main amd64 man-db amd64 2.13.1-1build1 [1392 kB] 202s Get:58 http://ftpmaster.internal/ubuntu resolute/main amd64 tcpdump amd64 4.99.5-2ubuntu3 [477 kB] 202s Get:59 http://ftpmaster.internal/ubuntu resolute/main amd64 wget amd64 1.25.0-2ubuntu4 [353 kB] 202s Get:60 http://ftpmaster.internal/ubuntu resolute/main amd64 ubuntu-standard amd64 1.564 [13.3 kB] 202s Get:61 http://ftpmaster.internal/ubuntu resolute/main amd64 3cpio amd64 0.14.0-1ubuntu1 [285 kB] 202s Get:62 http://ftpmaster.internal/ubuntu resolute/main amd64 bpftool amd64 7.7.0+6.19.0-3.3 [1229 kB] 204s Get:63 http://ftpmaster.internal/ubuntu resolute/main amd64 busybox-initramfs amd64 1:1.37.0-7ubuntu1 [191 kB] 204s Get:64 http://ftpmaster.internal/ubuntu resolute/main amd64 cryptsetup-bin amd64 2:2.8.0-1ubuntu3 [228 kB] 204s Get:65 http://ftpmaster.internal/ubuntu resolute/main amd64 dracut-install amd64 109-11ubuntu1 [45.8 kB] 204s Get:66 http://ftpmaster.internal/ubuntu resolute/main amd64 hwdata all 0.394-1build1 [1566 B] 204s Get:67 http://ftpmaster.internal/ubuntu resolute/main amd64 pnp.ids all 0.394-1build1 [29.6 kB] 204s Get:68 http://ftpmaster.internal/ubuntu resolute/main amd64 libdrm-amdgpu1 amd64 2.4.131-1 [23.2 kB] 204s Get:69 http://ftpmaster.internal/ubuntu resolute/main amd64 libevent-core-2.1-7t64 amd64 2.1.12-stable-10build2 [93.1 kB] 204s Get:70 http://ftpmaster.internal/ubuntu resolute/main amd64 libgdbm-compat4t64 amd64 1.26-1build1 [6796 B] 204s Get:71 http://ftpmaster.internal/ubuntu resolute/main amd64 libgudev-1.0-0 amd64 1:238-7build1 [15.9 kB] 204s Get:72 http://ftpmaster.internal/ubuntu resolute/main amd64 libnpth0t64 amd64 1.8-3build1 [9302 B] 204s Get:73 http://ftpmaster.internal/ubuntu resolute/main amd64 libonig5 amd64 6.9.10-1build1 [174 kB] 204s Get:74 http://ftpmaster.internal/ubuntu resolute/main amd64 libpython3.14-minimal amd64 3.14.2-1 [920 kB] 206s Get:75 http://ftpmaster.internal/ubuntu resolute/main amd64 libpython3.14-stdlib amd64 3.14.2-1 [2398 kB] 210s Get:76 http://ftpmaster.internal/ubuntu resolute/main amd64 libpython3.14 amd64 3.14.2-1 [2568 kB] 214s Get:77 http://ftpmaster.internal/ubuntu resolute/main amd64 libwrap0 amd64 7.6.q-36build2 [48.5 kB] 214s Get:78 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-modules-6.19.0-3-generic amd64 6.19.0-3.3 [171 MB] 544s Get:79 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-image-6.19.0-3-generic amd64 6.19.0-3.3+1 [16.8 MB] 573s Get:80 http://ftpmaster.internal/ubuntu resolute/main amd64 amd64-microcode amd64 3.20251202.1ubuntu1 [459 kB] 573s Get:81 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-generic amd64 6.19.0-3.3 [1698 B] 573s Get:82 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-image-generic amd64 6.19.0-3.3 [12.2 kB] 573s Get:83 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-virtual amd64 6.19.0-3.3 [1700 B] 573s Get:84 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-image-virtual amd64 6.19.0-3.3 [12.1 kB] 573s Get:85 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-headers-virtual amd64 6.19.0-3.3 [1646 B] 573s Get:86 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-headers-6.19.0-3 all 6.19.0-3.3 [14.9 MB] 612s Get:87 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-headers-6.19.0-3-generic amd64 6.19.0-3.3 [4330 kB] 618s Get:88 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-headers-generic amd64 6.19.0-3.3 [12.0 kB] 618s Get:89 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-perf amd64 6.19.0-3.3 [4480 kB] 628s Get:90 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-tools-common all 6.19.0-3.3 [345 kB] 628s Get:91 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-tools-6.19.0-3 amd64 6.19.0-3.3 [1455 kB] 631s Get:92 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-tools-6.19.0-3-generic amd64 6.19.0-3.3 [1612 B] 631s Get:93 http://ftpmaster.internal/ubuntu resolute/main amd64 patch amd64 2.8-2build1 [95.7 kB] 631s Get:94 http://ftpmaster.internal/ubuntu resolute/main amd64 pollinate all 4.33-4ubuntu5 [14.0 kB] 631s Get:95 http://ftpmaster.internal/ubuntu resolute/main amd64 python3-referencing all 0.36.2-1ubuntu2 [22.2 kB] 631s Get:96 http://ftpmaster.internal/ubuntu resolute/main amd64 ubuntu-kernel-accessories amd64 1.564 [13.1 kB] 631s dpkg-preconfigure: unable to re-open stdin: No such file or directory 631s Fetched 236 MB in 7min 23s (533 kB/s) 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../debianutils_5.23.2build1_amd64.deb ... 632s Unpacking debianutils (5.23.2build1) over (5.23.2) ... 632s Setting up debianutils (5.23.2build1) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../dash_0.5.12-12ubuntu3_amd64.deb ... 632s Unpacking dash (0.5.12-12ubuntu3) over (0.5.12-12ubuntu2) ... 632s Setting up dash (0.5.12-12ubuntu3) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../findutils_4.10.0-3build2_amd64.deb ... 632s Unpacking findutils (4.10.0-3build2) over (4.10.0-3build1) ... 632s Setting up findutils (4.10.0-3build2) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../sed_4.9-2build3_amd64.deb ... 632s Unpacking sed (4.9-2build3) over (4.9-2build2) ... 632s Setting up sed (4.9-2build3) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../tar_1.35+dfsg-3.1build2_amd64.deb ... 632s Unpacking tar (1.35+dfsg-3.1build2) over (1.35+dfsg-3.1build1) ... 632s Setting up tar (1.35+dfsg-3.1build2) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../libattr1_1%3a2.5.2-3build2_amd64.deb ... 632s Unpacking libattr1:amd64 (1:2.5.2-3build2) over (1:2.5.2-3build1) ... 632s Setting up libattr1:amd64 (1:2.5.2-3build2) ... 632s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 83957 files and directories currently installed.) 632s Preparing to unpack .../00-libbsd0_0.12.2-2build2_amd64.deb ... 632s Unpacking libbsd0:amd64 (0.12.2-2build2) over (0.12.2-2build1) ... 632s Preparing to unpack .../01-mawk_1.3.4.20260129-1_amd64.deb ... 632s Unpacking mawk (1.3.4.20260129-1) over (1.3.4.20250131-2) ... 632s Preparing to unpack .../02-libapt-pkg7.0_3.1.15_amd64.deb ... 632s Unpacking libapt-pkg7.0:amd64 (3.1.15) over (3.1.14) ... 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libmaxminddb0:amd64 (1.12.2-1build2) ... 639s Setting up libpython3.14-minimal:amd64 (3.14.2-1) ... 639s Setting up libsensors-config (1:3.6.2-2build1) ... 639s Setting up less (668-1build1) ... 639s Setting up linux-headers-6.19.0-3 (6.19.0-3.3) ... 639s Setting up libidn2-0:amd64 (2.3.8-4build1) ... 639s Setting up amd64-microcode (3.20251202.1ubuntu1) ... 639s amd64-microcode: microcode will be updated at next boot 639s Setting up man-db (2.13.1-1build1) ... 639s Updating database of manual pages ... 640s man-db.service is a disabled or a static unit not running, not starting it. 640s Setting up libjansson4:amd64 (2.14-2build4) ... 640s Setting up libglib2.0-0t64:amd64 (2.87.2-2) ... 640s No schema files found: doing nothing. 640s Setting up libglib2.0-data (2.87.2-2) ... 640s Setting up pollinate (4.33-4ubuntu5) ... 651s Setting up busybox-static (1:1.37.0-7ubuntu1) ... 651s Setting up libwrap0:amd64 (7.6.q-36build2) ... 651s Setting up linux-image-6.19.0-3-generic (6.19.0-3.3+1) ... 652s I: /boot/vmlinuz is now a symlink to vmlinuz-6.19.0-3-generic 652s I: /boot/initrd.img is now a symlink to initrd.img-6.19.0-3-generic 652s Setting up libdbus-1-3:amd64 (1.16.2-2ubuntu3) ... 652s Setting up shared-mime-info (2.4-5build3) ... 653s Setting up patch (2.8-2build1) ... 653s Setting up gir1.2-glib-2.0:amd64 (2.87.2-2) ... 653s Setting up libsensors5:amd64 (1:3.6.2-2build1) ... 653s Setting up busybox-initramfs (1:1.37.0-7ubuntu1) ... 653s Setting up libxtables12:amd64 (1.8.11-2ubuntu3) ... 653s Setting up lsof (4.99.4+dfsg-2build2) ... 653s Setting up libpci3:amd64 (1:3.14.0-1build2) ... 653s Setting up libdevmapper1.02.1:amd64 (2:1.02.205-2ubuntu3) ... 653s Setting up dracut-install (109-11ubuntu1) ... 653s Setting up dmsetup (2:1.02.205-2ubuntu3) ... 653s Setting up libnetfilter-conntrack3:amd64 (1.1.1-1) ... 653s Setting up pnp.ids (0.394-1build1) ... 653s Setting up dbus-session-bus-common (1.16.2-2ubuntu3) ... 653s Setting up python3-linkify-it (2.0.3-1ubuntu3) ... 653s Setting up libpcap0.8t64:amd64 (1.10.5-2ubuntu3) ... 653s Setting up libcryptsetup12:amd64 (2:2.8.0-1ubuntu3) ... 653s Setting up mawk (1.3.4.20260129-1) ... 653s Setting up libevent-core-2.1-7t64:amd64 (2.1.12-stable-10build2) ... 653s Setting up libusb-1.0-0:amd64 (2:1.0.29-2build1) ... 653s Setting up libapt-pkg7.0:amd64 (3.1.15) ... 653s Setting up linux-image-virtual (6.19.0-3.3) ... 653s Setting up dbus-system-bus-common (1.16.2-2ubuntu3) ... 653s Setting up libbsd0:amd64 (0.12.2-2build2) ... 653s Setting up libdrm-common (2.4.131-1) ... 653s Setting up dbus-bin (1.16.2-2ubuntu3) ... 653s Setting up libonig5:amd64 (6.9.10-1build1) ... 653s Setting up libgudev-1.0-0:amd64 (1:238-7build1) ... 653s Setting up libbpf1:amd64 (1:1.6.2-1build1) ... 653s Setting up ethtool (1:6.15-3build1) ... 653s Setting up python3-referencing (0.36.2-1ubuntu2) ... 653s Setting up libxkbcommon0:amd64 (1.13.1-1) ... 653s Setting up cryptsetup-bin (2:2.8.0-1ubuntu3) ... 653s Setting up linux-headers-6.19.0-3-generic (6.19.0-3.3) ... 653s Setting up tcpdump (4.99.5-2ubuntu3) ... 653s Setting up linux-image-generic (6.19.0-3.3) ... 653s Setting up apt (3.1.15) ... 654s Setting up wget (1.25.0-2ubuntu4) ... 654s Setting up libgirepository-2.0-0:amd64 (2.87.2-2) ... 654s Setting up libpython3.14-stdlib:amd64 (3.14.2-1) ... 654s Setting up iptables (1.8.11-2ubuntu3) ... 654s Setting up iproute2 (6.18.0-1ubuntu1) ... 654s Setting up linux-headers-generic (6.19.0-3.3) ... 654s Setting up dbus-daemon (1.16.2-2ubuntu3) ... 654s Setting up gir1.2-girepository-3.0:amd64 (2.87.2-2) ... 654s Setting up hwdata (0.394-1build1) ... 654s Setting up dbus-user-session (1.16.2-2ubuntu3) ... 654s Setting up dbus (1.16.2-2ubuntu3) ... 654s A reboot is required to replace the running dbus-daemon. 654s Please reboot the system when convenient. 654s Setting up pciutils (1:3.14.0-1build2) ... 654s Setting up python3-markdown-it (3.0.0-3build1) ... 654s Setting up libdrm2:amd64 (2.4.131-1) ... 654s Setting up libpython3.14:amd64 (3.14.2-1) ... 654s Setting up linux-tools-common (6.19.0-3.3) ... 654s Setting up libdrm-amdgpu1:amd64 (2.4.131-1) ... 654s Setting up linux-headers-virtual (6.19.0-3.3) ... 654s Setting up linux-generic (6.19.0-3.3) ... 654s Setting up linux-tools-6.19.0-3 (6.19.0-3.3) ... 654s Setting up ubuntu-standard (1.564) ... 654s Setting up linux-virtual (6.19.0-3.3) ... 654s Setting up linux-perf (6.19.0-3.3) ... 654s Setting up linux-tools-6.19.0-3-generic (6.19.0-3.3) ... 654s Processing triggers for debianutils (5.23.2build1) ... 654s Processing triggers for install-info (7.2-5) ... 654s Processing triggers for initramfs-tools (0.150ubuntu7) ... 654s update-initramfs: Generating /boot/initrd.img-6.18.0-9-generic 659s Processing triggers for libc-bin (2.42-2ubuntu4) ... 659s Processing triggers for linux-image-6.19.0-3-generic (6.19.0-3.3+1) ... 659s /etc/kernel/postinst.d/initramfs-tools: 659s update-initramfs: Generating /boot/initrd.img-6.19.0-3-generic 662s /etc/kernel/postinst.d/zz-update-grub: 662s Sourcing file `/etc/default/grub' 662s Sourcing file `/etc/default/grub.d/50-cloudimg-settings.cfg' 662s Sourcing file `/etc/default/grub.d/90-autopkgtest.cfg' 662s Generating grub configuration file ... 662s Found linux image: /boot/vmlinuz-6.19.0-3-generic 662s Found initrd image: /boot/initrd.img-6.19.0-3-generic 662s Found linux image: /boot/vmlinuz-6.18.0-9-generic 662s Found initrd image: /boot/initrd.img-6.18.0-9-generic 663s Warning: os-prober will not be executed to detect other bootable partitions. 663s Systems on them will not be added to the GRUB boot configuration. 663s Check GRUB_DISABLE_OS_PROBER documentation entry. 663s Adding boot menu entry for UEFI Firmware Settings ... 663s done 663s autopkgtest [23:36:33]: upgrading testbed (apt dist-upgrade and autopurge) 663s Reading package lists... 663s Building dependency tree... 663s Reading state information... 664s Calculating upgrade... 664s The following package was automatically installed and is no longer required: 664s libpython3.13 664s Use 'sudo apt autoremove' to remove it. 664s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 664s Reading package lists... 664s Building dependency tree... 664s Reading state information... 664s Solving dependencies... 664s The following packages will be REMOVED: 664s libpython3.13* 664s 0 upgraded, 0 newly installed, 1 to remove and 0 not upgraded. 664s After this operation, 7599 kB disk space will be freed. 664s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 125268 files and directories currently installed.) 664s Removing libpython3.13:amd64 (3.13.11-1) ... 664s Processing triggers for libc-bin (2.42-2ubuntu4) ... 665s autopkgtest [23:36:35]: rebooting testbed after setup commands that affected boot 692s autopkgtest [23:37:02]: testbed running kernel: Linux 6.19.0-3-generic #3-Ubuntu SMP PREEMPT_DYNAMIC Fri Jan 23 20:01:24 UTC 2026 694s autopkgtest [23:37:04]: @@@@@@@@@@@@@@@@@@@@ apt-source r-cran-dosefinding 696s Get:1 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (dsc) [2322 B] 696s Get:2 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (tar) [698 kB] 696s Get:3 http://ftpmaster.internal/ubuntu resolute/universe r-cran-dosefinding 1.3-1-1 (diff) [4244 B] 697s gpgv: Signature made Fri Mar 14 00:07:33 2025 UTC 697s gpgv: using RSA key 73471499CC60ED9EEE805946C5BD6C8F2295D502 697s gpgv: issuer "plessy@debian.org" 697s gpgv: Can't check signature: No public key 697s dpkg-source: warning: cannot verify inline signature for ./r-cran-dosefinding_1.3-1-1.dsc: no acceptable signature found 697s autopkgtest [23:37:07]: testing package r-cran-dosefinding version 1.3-1-1 697s autopkgtest [23:37:07]: build not needed 698s autopkgtest [23:37:08]: test run-unit-test: preparing testbed 699s Reading package lists... 699s Building dependency tree... 699s Reading state information... 699s Solving dependencies... 699s The following NEW packages will be installed: 699s fontconfig fontconfig-config fonts-dejavu-core fonts-dejavu-mono 699s fonts-font-awesome fonts-glyphicons-halflings fonts-mathjax 699s javascript-common libblas3 libcairo2 libdatrie1 libdeflate0 libfontconfig1 699s libgfortran5 libgomp1 libgraphite2-3 libharfbuzz0b libice6 libjbig0 699s libjpeg-turbo8 libjpeg8 libjs-bootstrap libjs-bootstrap4 libjs-d3 699s libjs-es5-shim libjs-highlight.js libjs-jquery libjs-jquery-datatables 699s libjs-jquery-selectize.js libjs-jquery-ui libjs-json libjs-mathjax 699s libjs-microplugin.js libjs-modernizr libjs-popper.js libjs-prettify 699s libjs-sifter.js libjs-twitter-bootstrap-datepicker liblapack3 liblerc4 699s liblua5.4-0 libpango-1.0-0 libpangocairo-1.0-0 libpangoft2-1.0-0 699s libpaper-utils libpaper2 libpixman-1-0 libsharpyuv0 libsm6 libtcl8.6 699s libthai-data libthai0 libtiff6 libtk8.6 libwebp7 libxcb-render0 libxcb-shm0 699s libxft2 libxrender1 libxss1 libxt6t64 node-bootstrap-sass node-html5shiv 699s node-normalize.css pandoc pandoc-data r-base-core r-cran-base64enc 699s r-cran-brio r-cran-bslib r-cran-cachem r-cran-callr r-cran-cli 699s r-cran-codetools r-cran-commonmark r-cran-crayon r-cran-desc r-cran-diffobj 699s r-cran-digest r-cran-dosefinding r-cran-evaluate r-cran-fansi r-cran-farver 699s r-cran-fastmap r-cran-fontawesome r-cran-fs r-cran-ggplot2 r-cran-glue 699s r-cran-gtable r-cran-highr r-cran-htmltools r-cran-httpuv r-cran-isoband 699s r-cran-jquerylib r-cran-jsonlite r-cran-knitr r-cran-labeling r-cran-later 699s r-cran-lattice r-cran-lifecycle r-cran-littler r-cran-magrittr r-cran-mass 699s r-cran-matrix r-cran-memoise r-cran-mgcv r-cran-mime r-cran-multcomp 699s r-cran-mvtnorm r-cran-nlme r-cran-numderiv r-cran-pillar r-cran-pkgbuild 699s r-cran-pkgconfig r-cran-pkgkitten r-cran-pkgload r-cran-praise 699s r-cran-processx r-cran-promises r-cran-ps r-cran-quadprog r-cran-r6 699s r-cran-rappdirs r-cran-rcolorbrewer r-cran-rcpp r-cran-rlang 699s r-cran-rmarkdown r-cran-rprojroot r-cran-rsolnp r-cran-sandwich r-cran-sass 699s r-cran-scales r-cran-shiny r-cran-sourcetools r-cran-survival 699s r-cran-testthat r-cran-th.data r-cran-tibble r-cran-tinytex r-cran-truncnorm 699s r-cran-utf8 r-cran-vctrs r-cran-viridislite r-cran-waldo r-cran-withr 699s r-cran-xfun r-cran-xtable r-cran-yaml r-cran-zoo unzip x11-common xdg-utils 699s zip 699s 0 upgraded, 153 newly installed, 0 to remove and 0 not upgraded. 699s Need to get 154 MB of archives. 699s After this operation, 471 MB of additional disk space will be used. 699s Get:1 http://ftpmaster.internal/ubuntu resolute/main amd64 fonts-dejavu-mono all 2.37-8build1 [502 kB] 699s Get:2 http://ftpmaster.internal/ubuntu resolute/main amd64 fonts-dejavu-core all 2.37-8build1 [834 kB] 701s Get:3 http://ftpmaster.internal/ubuntu resolute/main amd64 fontconfig-config amd64 2.17.1-3ubuntu1 [38.5 kB] 701s Get:4 http://ftpmaster.internal/ubuntu resolute/main amd64 libfontconfig1 amd64 2.17.1-3ubuntu1 [144 kB] 701s Get:5 http://ftpmaster.internal/ubuntu resolute/main amd64 fontconfig amd64 2.17.1-3ubuntu1 [180 kB] 701s Get:6 http://ftpmaster.internal/ubuntu resolute/main amd64 fonts-font-awesome all 5.0.10+really4.7.0~dfsg-4.1build1 [531 kB] 702s Get:7 http://ftpmaster.internal/ubuntu resolute/universe amd64 fonts-glyphicons-halflings all 1.009~3.4.1+dfsg-6 [119 kB] 702s Get:8 http://ftpmaster.internal/ubuntu resolute/main amd64 fonts-mathjax all 2.7.9+dfsg-1build1 [2283 kB] 706s Get:9 http://ftpmaster.internal/ubuntu resolute/main amd64 javascript-common all 12+nmu1build1 [4864 B] 706s Get:10 http://ftpmaster.internal/ubuntu resolute/main amd64 libblas3 amd64 3.12.1-7ubuntu1 [260 kB] 706s Get:11 http://ftpmaster.internal/ubuntu resolute/main amd64 libpixman-1-0 amd64 0.46.4-1 [287 kB] 706s Get:12 http://ftpmaster.internal/ubuntu resolute/main amd64 libxcb-render0 amd64 1.17.0-2ubuntu1 [16.2 kB] 706s Get:13 http://ftpmaster.internal/ubuntu resolute/main amd64 libxcb-shm0 amd64 1.17.0-2ubuntu1 [5808 B] 706s Get:14 http://ftpmaster.internal/ubuntu resolute/main amd64 libxrender1 amd64 1:0.9.12-1 [19.8 kB] 706s Get:15 http://ftpmaster.internal/ubuntu resolute/main amd64 libcairo2 amd64 1.18.4-3 [579 kB] 706s Get:16 http://ftpmaster.internal/ubuntu resolute/main amd64 libdatrie1 amd64 0.2.14-1 [19.8 kB] 706s Get:17 http://ftpmaster.internal/ubuntu resolute/main amd64 libdeflate0 amd64 1.23-2build1 [51.6 kB] 706s Get:18 http://ftpmaster.internal/ubuntu resolute/main amd64 libgfortran5 amd64 15.2.0-12ubuntu1 [939 kB] 708s Get:19 http://ftpmaster.internal/ubuntu resolute/main amd64 libgomp1 amd64 15.2.0-12ubuntu1 [151 kB] 708s Get:20 http://ftpmaster.internal/ubuntu resolute/main amd64 libgraphite2-3 amd64 1.3.14-11ubuntu1 [73.7 kB] 708s Get:21 http://ftpmaster.internal/ubuntu resolute/main amd64 libharfbuzz0b amd64 12.3.2-1 [519 kB] 708s Get:22 http://ftpmaster.internal/ubuntu resolute/main amd64 x11-common all 1:7.7+24ubuntu1 [22.4 kB] 708s Get:23 http://ftpmaster.internal/ubuntu resolute/main amd64 libice6 amd64 2:1.1.1-1build1 [44.0 kB] 708s Get:24 http://ftpmaster.internal/ubuntu resolute/main amd64 libjpeg-turbo8 amd64 2.1.5-4ubuntu3 [156 kB] 708s Get:25 http://ftpmaster.internal/ubuntu resolute/main amd64 libjpeg8 amd64 8c-2ubuntu11 [2148 B] 708s Get:26 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-bootstrap all 3.4.1+dfsg-6 [129 kB] 708s Get:27 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-popper.js all 1.16.1+ds-6build1 [53.8 kB] 708s Get:28 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-bootstrap4 all 4.6.2+dfsg-1 [532 kB] 709s Get:29 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-d3 all 3.5.17-4build1 [136 kB] 709s Get:30 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-es5-shim all 4.6.7-2 [39.8 kB] 709s Get:31 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-highlight.js all 10.7.3+dfsg-2 [144 kB] 709s Get:32 http://ftpmaster.internal/ubuntu resolute/main amd64 libjs-jquery all 3.7.1+dfsg+~3.5.33-1build1 [321 kB] 709s Get:33 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-jquery-datatables all 1.11.5+dfsg-2build1 [145 kB] 709s Get:34 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-sifter.js all 0.6.0+dfsg-3 [12.6 kB] 709s Get:35 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-microplugin.js all 0.0.3+dfsg-2 [3946 B] 709s Get:36 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-jquery-selectize.js all 0.12.6+dfsg-1.1 [51.0 kB] 709s Get:37 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-jquery-ui all 1.13.2+dfsg-1build1 [251 kB] 709s Get:38 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-json all 0~20221030+~1.0.8-1build1 [20.6 kB] 709s Get:39 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-prettify all 2015.12.04+dfsg-3 [41.4 kB] 709s Get:40 http://ftpmaster.internal/ubuntu resolute/main amd64 liblapack3 amd64 3.12.1-7ubuntu1 [2739 kB] 714s Get:41 http://ftpmaster.internal/ubuntu resolute/main amd64 liblerc4 amd64 4.0.0+ds-5ubuntu2 [207 kB] 714s Get:42 http://ftpmaster.internal/ubuntu resolute/main amd64 liblua5.4-0 amd64 5.4.8-1 [174 kB] 714s Get:43 http://ftpmaster.internal/ubuntu resolute/main amd64 libthai-data all 0.1.30-1 [155 kB] 714s Get:44 http://ftpmaster.internal/ubuntu resolute/main amd64 libthai0 amd64 0.1.30-1 [19.2 kB] 714s Get:45 http://ftpmaster.internal/ubuntu resolute/main amd64 libpango-1.0-0 amd64 1.57.0-1 [241 kB] 714s Get:46 http://ftpmaster.internal/ubuntu resolute/main amd64 libpangoft2-1.0-0 amd64 1.57.0-1 [53.3 kB] 714s Get:47 http://ftpmaster.internal/ubuntu resolute/main amd64 libpangocairo-1.0-0 amd64 1.57.0-1 [29.0 kB] 714s Get:48 http://ftpmaster.internal/ubuntu resolute/main amd64 libpaper2 amd64 2.2.5-0.3build1 [17.3 kB] 714s Get:49 http://ftpmaster.internal/ubuntu resolute/main amd64 libpaper-utils amd64 2.2.5-0.3build1 [15.6 kB] 714s Get:50 http://ftpmaster.internal/ubuntu resolute/main amd64 libsharpyuv0 amd64 1.5.0-0.1build1 [17.6 kB] 714s Get:51 http://ftpmaster.internal/ubuntu resolute/main amd64 libsm6 amd64 2:1.2.6-1build1 [16.9 kB] 714s Get:52 http://ftpmaster.internal/ubuntu resolute/main amd64 libtcl8.6 amd64 8.6.17+dfsg-1build1 [1003 kB] 715s Get:53 http://ftpmaster.internal/ubuntu resolute/main amd64 libjbig0 amd64 2.1-6.1ubuntu3 [30.0 kB] 715s Get:54 http://ftpmaster.internal/ubuntu resolute/main amd64 libwebp7 amd64 1.5.0-0.1build1 [264 kB] 715s Get:55 http://ftpmaster.internal/ubuntu resolute/main amd64 libtiff6 amd64 4.7.0-3ubuntu3 [209 kB] 715s Get:56 http://ftpmaster.internal/ubuntu resolute/main amd64 libxft2 amd64 2.3.6-1build2 [45.1 kB] 715s Get:57 http://ftpmaster.internal/ubuntu resolute/main amd64 libxss1 amd64 1:1.2.3-1build4 [7084 B] 715s Get:58 http://ftpmaster.internal/ubuntu resolute/main amd64 libtk8.6 amd64 8.6.17-1 [823 kB] 717s Get:59 http://ftpmaster.internal/ubuntu resolute/main amd64 libxt6t64 amd64 1:1.2.1-1.3 [173 kB] 717s Get:60 http://ftpmaster.internal/ubuntu resolute/universe amd64 node-bootstrap-sass all 3.4.3-2 [187 kB] 717s Get:61 http://ftpmaster.internal/ubuntu resolute/universe amd64 node-html5shiv all 3.7.3+dfsg-5 [13.5 kB] 717s Get:62 http://ftpmaster.internal/ubuntu resolute/universe amd64 node-normalize.css all 8.0.1-5.1 [10.4 kB] 717s Get:63 http://ftpmaster.internal/ubuntu resolute/universe amd64 pandoc-data all 3.1.11.1-3build1 [78.8 kB] 717s Get:64 http://ftpmaster.internal/ubuntu resolute/universe amd64 pandoc amd64 3.1.11.1+ds-4 [27.2 MB] 767s Get:65 http://ftpmaster.internal/ubuntu resolute/main amd64 zip amd64 3.0-15ubuntu3 [175 kB] 767s Get:66 http://ftpmaster.internal/ubuntu resolute/main amd64 unzip amd64 6.0-29ubuntu1 [180 kB] 767s Get:67 http://ftpmaster.internal/ubuntu resolute/main amd64 xdg-utils all 1.2.1-2ubuntu2 [66.1 kB] 767s Get:68 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-base-core amd64 4.5.2-1ubuntu2 [28.8 MB] 821s Get:69 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-base64enc amd64 0.1-3-3build1 [28.5 kB] 821s Get:70 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-brio amd64 1.1.5-1 [39.0 kB] 821s Get:71 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rlang amd64 1.1.5-3 [1721 kB] 824s Get:72 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-fastmap amd64 1.2.0-1 [73.8 kB] 825s Get:73 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-cachem amd64 1.1.0-1 [74.1 kB] 825s Get:74 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-digest amd64 0.6.39-1 [203 kB] 825s Get:75 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-htmltools amd64 0.5.8.1-1 [373 kB] 825s Get:76 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-jquerylib all 0.1.4+dfsg-5 [13.7 kB] 825s Get:77 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-jsonlite amd64 1.9.1+dfsg-1 [447 kB] 825s Get:78 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-cli amd64 3.6.4-1 [1394 kB] 827s Get:79 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-lifecycle all 1.0.5+dfsg-1 [120 kB] 827s Get:80 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-memoise all 2.0.1-1build1 [54.5 kB] 827s Get:81 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-mime amd64 0.12-2 [35.8 kB] 827s Get:82 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-fs amd64 1.6.5+dfsg-1 [246 kB] 827s Get:83 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-r6 all 2.6.1-1 [101 kB] 827s Get:84 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rappdirs amd64 0.3.3-1build1 [49.3 kB] 827s Get:85 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-sass amd64 0.4.9+dfsg-1 [1001 kB] 829s Get:86 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-bslib all 0.9.0+dfsg-3build1 [4560 kB] 836s Get:87 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-ps amd64 1.9.0-1 [408 kB] 836s Get:88 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-processx amd64 3.8.6-1 [365 kB] 836s Get:89 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-callr all 3.7.6-1 [458 kB] 836s Get:90 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-codetools all 0.2-20-1build1 [91.1 kB] 836s Get:91 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-commonmark amd64 1.9.5-1 [138 kB] 836s Get:92 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-crayon all 1.5.3-1 [165 kB] 836s Get:93 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-desc all 1.4.3-1 [359 kB] 836s Get:94 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-diffobj amd64 0.3.5-1build1 [1156 kB] 838s Get:95 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-glue amd64 1.8.0-1 [164 kB] 838s Get:96 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-gtable all 0.3.6+dfsg-1 [199 kB] 838s Get:97 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-isoband amd64 0.2.7-1 [1481 kB] 841s Get:98 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-mass amd64 7.3-65-1 [1116 kB] 843s Get:99 http://ftpmaster.internal/ubuntu resolute-proposed/universe amd64 r-cran-lattice amd64 0.22-9-1 [1399 kB] 846s Get:100 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-nlme amd64 3.1.168-1 [2320 kB] 850s Get:101 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-matrix amd64 1.7-4-1 [4220 kB] 858s Get:102 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-mgcv amd64 1.9-4-1 [3556 kB] 865s Get:103 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-farver amd64 2.1.2-1 [1355 kB] 867s Get:104 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-labeling all 0.4.3-1 [62.1 kB] 867s Get:105 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rcolorbrewer all 1.1-3-1build2 [54.0 kB] 867s Get:106 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-viridislite all 0.4.3-1 [1088 kB] 869s Get:107 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-scales all 1.4.0-1 [725 kB] 870s Get:108 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-fansi amd64 1.0.6-2 [626 kB] 871s Get:109 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-magrittr amd64 2.0.3-1 [154 kB] 871s Get:110 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-utf8 amd64 1.2.4-1 [140 kB] 871s Get:111 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-vctrs amd64 0.6.5-1 [1335 kB] 874s Get:112 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-pillar all 1.11.1+dfsg-1 [456 kB] 874s Get:113 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-pkgconfig all 2.0.3-2build2 [20.4 kB] 874s Get:114 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-tibble amd64 3.2.1+dfsg-3 [419 kB] 874s Get:115 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-withr all 3.0.2+dfsg-1 [214 kB] 874s Get:116 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-ggplot2 all 3.5.1+dfsg-1 [3940 kB] 881s Get:117 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-mvtnorm amd64 1.3-3-1build1 [921 kB] 883s Get:118 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-dosefinding amd64 1.3-1-1 [973 kB] 885s Get:119 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-evaluate all 1.0.5-1 [117 kB] 885s Get:120 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-fontawesome all 0.5.3-1 [1331 kB] 889s Get:121 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-xfun amd64 0.55+dfsg-1 [587 kB] 890s Get:122 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-highr all 0.11+dfsg-1 [38.5 kB] 890s Get:123 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-littler amd64 0.3.22-1 [85.5 kB] 890s Get:124 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-pkgkitten all 0.2.4-1 [27.2 kB] 890s Get:125 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rcpp amd64 1.1.0-1 [2021 kB] 894s Get:126 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-later amd64 1.4.1+dfsg-1 [154 kB] 894s Get:127 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-promises amd64 1.3.2+dfsg-1 [291 kB] 894s Get:128 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-httpuv amd64 1.6.15+dfsg-1 [510 kB] 894s Get:129 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-yaml amd64 2.3.10-1 [109 kB] 894s Get:130 http://ftpmaster.internal/ubuntu resolute/main amd64 libjs-mathjax all 2.7.9+dfsg-1build1 [6017 kB] 904s Get:131 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-knitr all 1.51+dfsg-1 [847 kB] 906s Get:132 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-survival amd64 3.8-6-1 [8274 kB] 922s Get:133 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-th.data all 1.1-5-1 [8740 kB] 938s Get:134 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-zoo amd64 1.8-15-1 [1025 kB] 940s Get:135 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-sandwich all 3.1-1-1build1 [1483 kB] 944s Get:136 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-multcomp all 1.4-29-1 [617 kB] 945s Get:137 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-numderiv all 2016.8-1.1-3build1 [116 kB] 945s Get:138 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-pkgbuild all 1.4.8-1 [219 kB] 945s Get:139 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rprojroot all 2.1.1-1 [131 kB] 945s Get:140 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-pkgload all 1.4.1-1 [252 kB] 945s Get:141 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-praise all 1.0.0-4build2 [20.9 kB] 945s Get:142 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-quadprog amd64 1.5-8-1build2 [32.6 kB] 945s Get:143 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-tinytex all 0.58-1 [148 kB] 945s Get:144 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-modernizr all 3.13.0-0.1build1 [100 kB] 945s Get:145 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-xtable all 1:1.8-4-2build1 [691 kB] 947s Get:146 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-sourcetools amd64 0.1.7-1-1 [48.1 kB] 947s Get:147 http://ftpmaster.internal/ubuntu resolute/universe amd64 libjs-twitter-bootstrap-datepicker all 1.3.1+dfsg1-4.1 [28.5 kB] 947s Get:148 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-shiny all 1.10.0+dfsg-2 [3124 kB] 958s Get:149 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rmarkdown all 2.30+dfsg-1 [1501 kB] 960s Get:150 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-truncnorm amd64 1.0-9-2 [25.3 kB] 960s Get:151 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-rsolnp all 1.16+dfsg-4build2 [248 kB] 960s Get:152 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-waldo all 0.6.2-1 [153 kB] 960s Get:153 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-cran-testthat amd64 3.2.3-1 [1651 kB] 963s Preconfiguring packages ... 964s Fetched 154 MB in 4min 24s (583 kB/s) 964s Selecting previously unselected package fonts-dejavu-mono. 964s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 125264 files and directories currently installed.) 964s Preparing to unpack .../000-fonts-dejavu-mono_2.37-8build1_all.deb ... 964s Unpacking fonts-dejavu-mono (2.37-8build1) ... 964s Selecting previously unselected package fonts-dejavu-core. 964s Preparing to unpack .../001-fonts-dejavu-core_2.37-8build1_all.deb ... 964s Unpacking fonts-dejavu-core (2.37-8build1) ... 964s Selecting previously unselected package fontconfig-config. 964s Preparing to unpack .../002-fontconfig-config_2.17.1-3ubuntu1_amd64.deb ... 964s Unpacking fontconfig-config (2.17.1-3ubuntu1) ... 964s Selecting previously unselected package libfontconfig1:amd64. 964s Preparing to unpack .../003-libfontconfig1_2.17.1-3ubuntu1_amd64.deb ... 964s Unpacking libfontconfig1:amd64 (2.17.1-3ubuntu1) ... 964s Selecting previously unselected package fontconfig. 964s Preparing to unpack .../004-fontconfig_2.17.1-3ubuntu1_amd64.deb ... 964s Unpacking fontconfig (2.17.1-3ubuntu1) ... 964s Selecting previously unselected package fonts-font-awesome. 964s Preparing to unpack .../005-fonts-font-awesome_5.0.10+really4.7.0~dfsg-4.1build1_all.deb ... 964s Unpacking fonts-font-awesome (5.0.10+really4.7.0~dfsg-4.1build1) ... 964s Selecting previously unselected package fonts-glyphicons-halflings. 964s Preparing to unpack .../006-fonts-glyphicons-halflings_1.009~3.4.1+dfsg-6_all.deb ... 964s Unpacking fonts-glyphicons-halflings (1.009~3.4.1+dfsg-6) ... 964s Selecting previously unselected package fonts-mathjax. 964s Preparing to unpack .../007-fonts-mathjax_2.7.9+dfsg-1build1_all.deb ... 964s Unpacking fonts-mathjax (2.7.9+dfsg-1build1) ... 964s Selecting previously unselected package javascript-common. 964s Preparing to unpack .../008-javascript-common_12+nmu1build1_all.deb ... 964s Unpacking javascript-common (12+nmu1build1) ... 964s Selecting previously unselected package libblas3:amd64. 964s Preparing to unpack .../009-libblas3_3.12.1-7ubuntu1_amd64.deb ... 964s Unpacking libblas3:amd64 (3.12.1-7ubuntu1) ... 964s Selecting previously unselected package libpixman-1-0:amd64. 964s Preparing to unpack .../010-libpixman-1-0_0.46.4-1_amd64.deb ... 964s Unpacking libpixman-1-0:amd64 (0.46.4-1) ... 964s Selecting previously unselected package libxcb-render0:amd64. 964s Preparing to unpack .../011-libxcb-render0_1.17.0-2ubuntu1_amd64.deb ... 964s Unpacking libxcb-render0:amd64 (1.17.0-2ubuntu1) ... 964s Selecting previously unselected package libxcb-shm0:amd64. 964s Preparing to unpack .../012-libxcb-shm0_1.17.0-2ubuntu1_amd64.deb ... 964s Unpacking libxcb-shm0:amd64 (1.17.0-2ubuntu1) ... 964s Selecting previously unselected package libxrender1:amd64. 964s Preparing to unpack .../013-libxrender1_1%3a0.9.12-1_amd64.deb ... 964s Unpacking libxrender1:amd64 (1:0.9.12-1) ... 964s Selecting previously unselected package libcairo2:amd64. 964s Preparing to unpack .../014-libcairo2_1.18.4-3_amd64.deb ... 964s Unpacking libcairo2:amd64 (1.18.4-3) ... 964s Selecting previously unselected package libdatrie1:amd64. 964s Preparing to unpack .../015-libdatrie1_0.2.14-1_amd64.deb ... 964s Unpacking libdatrie1:amd64 (0.2.14-1) ... 964s Selecting previously unselected package libdeflate0:amd64. 964s Preparing to unpack .../016-libdeflate0_1.23-2build1_amd64.deb ... 964s Unpacking libdeflate0:amd64 (1.23-2build1) ... 964s Selecting previously unselected package libgfortran5:amd64. 964s Preparing to unpack .../017-libgfortran5_15.2.0-12ubuntu1_amd64.deb ... 964s Unpacking libgfortran5:amd64 (15.2.0-12ubuntu1) ... 964s Selecting previously unselected package libgomp1:amd64. 964s Preparing to unpack .../018-libgomp1_15.2.0-12ubuntu1_amd64.deb ... 964s Unpacking libgomp1:amd64 (15.2.0-12ubuntu1) ... 964s Selecting previously unselected package libgraphite2-3:amd64. 964s Preparing to unpack .../019-libgraphite2-3_1.3.14-11ubuntu1_amd64.deb ... 964s Unpacking libgraphite2-3:amd64 (1.3.14-11ubuntu1) ... 964s Selecting previously unselected package libharfbuzz0b:amd64. 964s Preparing to unpack .../020-libharfbuzz0b_12.3.2-1_amd64.deb ... 964s Unpacking libharfbuzz0b:amd64 (12.3.2-1) ... 964s Selecting previously unselected package x11-common. 964s Preparing to unpack .../021-x11-common_1%3a7.7+24ubuntu1_all.deb ... 964s Unpacking x11-common (1:7.7+24ubuntu1) ... 964s Selecting previously unselected package libice6:amd64. 964s Preparing to unpack .../022-libice6_2%3a1.1.1-1build1_amd64.deb ... 964s Unpacking libice6:amd64 (2:1.1.1-1build1) ... 964s Selecting previously unselected package libjpeg-turbo8:amd64. 964s Preparing to unpack .../023-libjpeg-turbo8_2.1.5-4ubuntu3_amd64.deb ... 964s Unpacking libjpeg-turbo8:amd64 (2.1.5-4ubuntu3) ... 964s Selecting previously unselected package libjpeg8:amd64. 964s Preparing to unpack .../024-libjpeg8_8c-2ubuntu11_amd64.deb ... 964s Unpacking libjpeg8:amd64 (8c-2ubuntu11) ... 964s Selecting previously unselected package libjs-bootstrap. 964s Preparing to unpack .../025-libjs-bootstrap_3.4.1+dfsg-6_all.deb ... 964s Unpacking libjs-bootstrap (3.4.1+dfsg-6) ... 964s Selecting previously unselected package libjs-popper.js. 964s Preparing to unpack .../026-libjs-popper.js_1.16.1+ds-6build1_all.deb ... 964s Unpacking libjs-popper.js (1.16.1+ds-6build1) ... 964s Selecting previously unselected package libjs-bootstrap4. 964s Preparing to unpack .../027-libjs-bootstrap4_4.6.2+dfsg-1_all.deb ... 964s Unpacking libjs-bootstrap4 (4.6.2+dfsg-1) ... 964s Selecting previously unselected package libjs-d3. 964s Preparing to unpack .../028-libjs-d3_3.5.17-4build1_all.deb ... 964s Unpacking libjs-d3 (3.5.17-4build1) ... 964s Selecting previously unselected package libjs-es5-shim. 964s Preparing to unpack .../029-libjs-es5-shim_4.6.7-2_all.deb ... 964s Unpacking libjs-es5-shim (4.6.7-2) ... 964s Selecting previously unselected package libjs-highlight.js. 964s Preparing to unpack .../030-libjs-highlight.js_10.7.3+dfsg-2_all.deb ... 964s Unpacking libjs-highlight.js (10.7.3+dfsg-2) ... 964s Selecting previously unselected package libjs-jquery. 964s Preparing to unpack .../031-libjs-jquery_3.7.1+dfsg+~3.5.33-1build1_all.deb ... 964s Unpacking libjs-jquery (3.7.1+dfsg+~3.5.33-1build1) ... 964s Selecting previously unselected package libjs-jquery-datatables. 964s Preparing to unpack .../032-libjs-jquery-datatables_1.11.5+dfsg-2build1_all.deb ... 964s Unpacking libjs-jquery-datatables (1.11.5+dfsg-2build1) ... 964s Selecting previously unselected package libjs-sifter.js. 964s Preparing to unpack .../033-libjs-sifter.js_0.6.0+dfsg-3_all.deb ... 964s Unpacking libjs-sifter.js (0.6.0+dfsg-3) ... 964s Selecting previously unselected package libjs-microplugin.js. 964s Preparing to unpack .../034-libjs-microplugin.js_0.0.3+dfsg-2_all.deb ... 964s Unpacking libjs-microplugin.js (0.0.3+dfsg-2) ... 964s Selecting previously unselected package libjs-jquery-selectize.js. 964s Preparing to unpack .../035-libjs-jquery-selectize.js_0.12.6+dfsg-1.1_all.deb ... 964s Unpacking libjs-jquery-selectize.js (0.12.6+dfsg-1.1) ... 964s Selecting previously unselected package libjs-jquery-ui. 964s Preparing to unpack .../036-libjs-jquery-ui_1.13.2+dfsg-1build1_all.deb ... 964s Unpacking libjs-jquery-ui (1.13.2+dfsg-1build1) ... 964s Selecting previously unselected package libjs-json. 964s Preparing to unpack .../037-libjs-json_0~20221030+~1.0.8-1build1_all.deb ... 964s Unpacking libjs-json (0~20221030+~1.0.8-1build1) ... 964s Selecting previously unselected package libjs-prettify. 964s Preparing to unpack .../038-libjs-prettify_2015.12.04+dfsg-3_all.deb ... 964s Unpacking libjs-prettify (2015.12.04+dfsg-3) ... 964s Selecting previously unselected package liblapack3:amd64. 964s Preparing to unpack .../039-liblapack3_3.12.1-7ubuntu1_amd64.deb ... 964s Unpacking liblapack3:amd64 (3.12.1-7ubuntu1) ... 964s Selecting previously unselected package liblerc4:amd64. 964s Preparing to unpack .../040-liblerc4_4.0.0+ds-5ubuntu2_amd64.deb ... 964s Unpacking liblerc4:amd64 (4.0.0+ds-5ubuntu2) ... 964s Selecting previously unselected package liblua5.4-0:amd64. 964s Preparing to unpack .../041-liblua5.4-0_5.4.8-1_amd64.deb ... 964s Unpacking liblua5.4-0:amd64 (5.4.8-1) ... 964s Selecting previously unselected package libthai-data. 964s Preparing to unpack .../042-libthai-data_0.1.30-1_all.deb ... 964s Unpacking libthai-data (0.1.30-1) ... 964s Selecting previously unselected package libthai0:amd64. 964s Preparing to unpack .../043-libthai0_0.1.30-1_amd64.deb ... 964s Unpacking 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package r-cran-fastmap. 965s Preparing to unpack .../071-r-cran-fastmap_1.2.0-1_amd64.deb ... 965s Unpacking r-cran-fastmap (1.2.0-1) ... 965s Selecting previously unselected package r-cran-cachem. 965s Preparing to unpack .../072-r-cran-cachem_1.1.0-1_amd64.deb ... 965s Unpacking r-cran-cachem (1.1.0-1) ... 965s Selecting previously unselected package r-cran-digest. 965s Preparing to unpack .../073-r-cran-digest_0.6.39-1_amd64.deb ... 965s Unpacking r-cran-digest (0.6.39-1) ... 965s Selecting previously unselected package r-cran-htmltools. 965s Preparing to unpack .../074-r-cran-htmltools_0.5.8.1-1_amd64.deb ... 965s Unpacking r-cran-htmltools (0.5.8.1-1) ... 965s Selecting previously unselected package r-cran-jquerylib. 965s Preparing to unpack .../075-r-cran-jquerylib_0.1.4+dfsg-5_all.deb ... 965s Unpacking r-cran-jquerylib (0.1.4+dfsg-5) ... 965s Selecting previously unselected package r-cran-jsonlite. 965s Preparing to unpack .../076-r-cran-jsonlite_1.9.1+dfsg-1_amd64.deb ... 965s 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unselected package r-cran-callr. 966s Preparing to unpack .../088-r-cran-callr_3.7.6-1_all.deb ... 966s Unpacking r-cran-callr (3.7.6-1) ... 966s Selecting previously unselected package r-cran-codetools. 966s Preparing to unpack .../089-r-cran-codetools_0.2-20-1build1_all.deb ... 966s Unpacking r-cran-codetools (0.2-20-1build1) ... 966s Selecting previously unselected package r-cran-commonmark. 966s Preparing to unpack .../090-r-cran-commonmark_1.9.5-1_amd64.deb ... 966s Unpacking r-cran-commonmark (1.9.5-1) ... 966s Selecting previously unselected package r-cran-crayon. 966s Preparing to unpack .../091-r-cran-crayon_1.5.3-1_all.deb ... 966s Unpacking r-cran-crayon (1.5.3-1) ... 966s Selecting previously unselected package r-cran-desc. 966s Preparing to unpack .../092-r-cran-desc_1.4.3-1_all.deb ... 966s Unpacking r-cran-desc (1.4.3-1) ... 966s Selecting previously unselected package r-cran-diffobj. 966s Preparing to unpack .../093-r-cran-diffobj_0.3.5-1build1_amd64.deb ... 966s Unpacking r-cran-diffobj (0.3.5-1build1) ... 966s Selecting previously unselected package r-cran-glue. 966s Preparing to unpack .../094-r-cran-glue_1.8.0-1_amd64.deb ... 966s Unpacking r-cran-glue (1.8.0-1) ... 966s Selecting previously unselected package r-cran-gtable. 966s Preparing to unpack .../095-r-cran-gtable_0.3.6+dfsg-1_all.deb ... 966s Unpacking r-cran-gtable (0.3.6+dfsg-1) ... 966s Selecting previously unselected package r-cran-isoband. 966s Preparing to unpack .../096-r-cran-isoband_0.2.7-1_amd64.deb ... 966s Unpacking r-cran-isoband (0.2.7-1) ... 966s Selecting previously unselected package r-cran-mass. 966s Preparing to unpack .../097-r-cran-mass_7.3-65-1_amd64.deb ... 966s Unpacking r-cran-mass (7.3-65-1) ... 966s Selecting previously unselected package r-cran-lattice. 966s Preparing to unpack .../098-r-cran-lattice_0.22-9-1_amd64.deb ... 966s Unpacking r-cran-lattice (0.22-9-1) ... 966s Selecting previously unselected package r-cran-nlme. 966s Preparing to unpack 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unselected package r-cran-viridislite. 966s Preparing to unpack .../105-r-cran-viridislite_0.4.3-1_all.deb ... 966s Unpacking r-cran-viridislite (0.4.3-1) ... 966s Selecting previously unselected package r-cran-scales. 966s Preparing to unpack .../106-r-cran-scales_1.4.0-1_all.deb ... 966s Unpacking r-cran-scales (1.4.0-1) ... 966s Selecting previously unselected package r-cran-fansi. 966s Preparing to unpack .../107-r-cran-fansi_1.0.6-2_amd64.deb ... 966s Unpacking r-cran-fansi (1.0.6-2) ... 966s Selecting previously unselected package r-cran-magrittr. 966s Preparing to unpack .../108-r-cran-magrittr_2.0.3-1_amd64.deb ... 966s Unpacking r-cran-magrittr (2.0.3-1) ... 966s Selecting previously unselected package r-cran-utf8. 966s Preparing to unpack .../109-r-cran-utf8_1.2.4-1_amd64.deb ... 966s Unpacking r-cran-utf8 (1.2.4-1) ... 966s Selecting previously unselected package r-cran-vctrs. 966s Preparing to unpack .../110-r-cran-vctrs_0.6.5-1_amd64.deb ... 966s Unpacking r-cran-vctrs 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.../127-r-cran-httpuv_1.6.15+dfsg-1_amd64.deb ... 966s Unpacking r-cran-httpuv (1.6.15+dfsg-1) ... 966s Selecting previously unselected package r-cran-yaml. 966s Preparing to unpack .../128-r-cran-yaml_2.3.10-1_amd64.deb ... 966s Unpacking r-cran-yaml (2.3.10-1) ... 966s Selecting previously unselected package libjs-mathjax. 966s Preparing to unpack .../129-libjs-mathjax_2.7.9+dfsg-1build1_all.deb ... 966s Unpacking libjs-mathjax (2.7.9+dfsg-1build1) ... 967s Selecting previously unselected package r-cran-knitr. 967s Preparing to unpack .../130-r-cran-knitr_1.51+dfsg-1_all.deb ... 967s Unpacking r-cran-knitr (1.51+dfsg-1) ... 967s Selecting previously unselected package r-cran-survival. 967s Preparing to unpack .../131-r-cran-survival_3.8-6-1_amd64.deb ... 967s Unpacking r-cran-survival (3.8-6-1) ... 967s Selecting previously unselected package r-cran-th.data. 967s Preparing to unpack .../132-r-cran-th.data_1.1-5-1_all.deb ... 967s Unpacking r-cran-th.data (1.1-5-1) ... 967s Selecting previously unselected package r-cran-zoo. 967s Preparing to unpack .../133-r-cran-zoo_1.8-15-1_amd64.deb ... 967s Unpacking r-cran-zoo (1.8-15-1) ... 967s Selecting previously unselected package r-cran-sandwich. 967s Preparing to unpack .../134-r-cran-sandwich_3.1-1-1build1_all.deb ... 967s Unpacking r-cran-sandwich (3.1-1-1build1) ... 967s Selecting previously unselected package r-cran-multcomp. 967s Preparing to unpack .../135-r-cran-multcomp_1.4-29-1_all.deb ... 967s Unpacking r-cran-multcomp (1.4-29-1) ... 967s Selecting previously unselected package r-cran-numderiv. 967s Preparing to unpack .../136-r-cran-numderiv_2016.8-1.1-3build1_all.deb ... 967s Unpacking r-cran-numderiv (2016.8-1.1-3build1) ... 967s Selecting previously unselected package r-cran-pkgbuild. 967s Preparing to unpack .../137-r-cran-pkgbuild_1.4.8-1_all.deb ... 967s Unpacking r-cran-pkgbuild (1.4.8-1) ... 967s Selecting previously unselected package r-cran-rprojroot. 967s Preparing to unpack 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967s Selecting previously unselected package r-cran-xtable. 967s Preparing to unpack .../144-r-cran-xtable_1%3a1.8-4-2build1_all.deb ... 967s Unpacking r-cran-xtable (1:1.8-4-2build1) ... 967s Selecting previously unselected package r-cran-sourcetools. 967s Preparing to unpack .../145-r-cran-sourcetools_0.1.7-1-1_amd64.deb ... 967s Unpacking r-cran-sourcetools (0.1.7-1-1) ... 967s Selecting previously unselected package libjs-twitter-bootstrap-datepicker. 967s Preparing to unpack .../146-libjs-twitter-bootstrap-datepicker_1.3.1+dfsg1-4.1_all.deb ... 967s Unpacking libjs-twitter-bootstrap-datepicker (1.3.1+dfsg1-4.1) ... 967s Selecting previously unselected package r-cran-shiny. 967s Preparing to unpack .../147-r-cran-shiny_1.10.0+dfsg-2_all.deb ... 967s Unpacking r-cran-shiny (1.10.0+dfsg-2) ... 967s Selecting previously unselected package r-cran-rmarkdown. 967s Preparing to unpack .../148-r-cran-rmarkdown_2.30+dfsg-1_all.deb ... 967s Unpacking r-cran-rmarkdown (2.30+dfsg-1) ... 967s 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Processing triggers for man-db (2.13.1-1build1) ... 971s Processing triggers for install-info (7.2-5) ... 971s autopkgtest [23:41:41]: test run-unit-test: [----------------------- 972s Loading required package: DoseFinding 972s Dose Response Model 972s 972s Model: linear 972s Fit-type: general 972s 972s Coefficients dose-response model 972s delta 972s 0.07484 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 3.472 972s Dose Response Model 972s 972s Model: linear 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 delta 972s 0.33400 0.07484 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 3.472 972s Dose Response Model 972s 972s Model: quadratic 972s Fit-type: general 972s 972s Coefficients dose-response model 972s b1 b2 972s 0.22800 -0.03811 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.9281 972s Dose Response Model 972s 972s Model: quadratic 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 b1 b2 972s 0.24950 0.22800 -0.03811 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.9281 972s Dose Response Model 972s 972s Model: linlog 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 delta 972s 0.47790 0.07728 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.1605 972s Dose Response Model 972s 972s Model: emax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s eMax ed50 972s 0.3771 0.3630 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.09815 972s Dose Response Model 972s 972s Model: emax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax ed50 972s 0.2221 0.3771 0.3630 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.09815 972s Dose Response Model 972s 972s Model: sigEmax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s eMax ed50 h 972s 0.4714 0.4880 0.5000 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.07825 972s Dose Response Model 972s 972s Model: sigEmax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax ed50 h 972s 0.2223 0.4714 0.4880 0.5000 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.07825 972s Dose Response Model 972s 972s Model: exponential 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e1 delta 972s 0.4391 8.0000 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 4.102 972s Dose Response Model 972s 972s Model: exponential 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 e1 delta 972s 0.3510 0.4391 8.0000 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 4.102 972s Dose Response Model 972s 972s Model: logistic 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax ed50 delta 972s -0.1095 0.6665 0.0040 0.4217 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.1951 972s Dose Response Model 972s 972s Model: betaMod 972s Fit-type: general 972s 972s Coefficients dose-response model 972s eMax delta1 delta2 972s 0.3468 0.2216 0.0500 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.0783 972s Dose Response Model 972s 972s Model: betaMod 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax delta1 delta2 972s 0.2222 0.3468 0.2216 0.0500 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.0783 972s Dose Response Model 972s 972s Model: linInt 972s Fit-type: general 972s 972s Coefficients dose-response model 972s d1 d2 d3 d4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0 972s Dose Response Model 972s 972s Model: linInt 972s Fit-type: general 972s 972s Coefficients dose-response model 972s d0 d1 d2 d3 d4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 1.484e-30 972s Dose Response Model 972s 972s Model: emax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s eMax ed50 972s 0.3771 0.3630 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.09815 972s Dose Response Model 972s 972s Model: emax 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax ed50 972s 0.2221 0.3771 0.3630 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.09815 972s Dose Response Model 972s 972s Model: betaMod 972s Fit-type: general 972s 972s Coefficients dose-response model 972s eMax delta1 delta2 972s 0.3468 0.2216 0.0500 972s 972s Fitted to: 972s 1 2 3 4 972s 0.2846 0.2965 0.3502 0.3480 972s 972s Generalized residual sum of squares: 0.0783 972s Dose Response Model 972s 972s Model: betaMod 972s Fit-type: general 972s 972s Coefficients dose-response model 972s e0 eMax delta1 delta2 972s 0.2222 0.3468 0.2216 0.0500 972s 972s Fitted to: 972s 0 1 2 3 4 972s 0.2220 0.5065 0.5185 0.5722 0.5700 972s 972s Generalized residual sum of squares: 0.0783 972s $fit 972s [1] 0.0000000 0.2756421 0.3165257 0.3387105 0.3466573 972s 972s $se.fit 972s [1] 0.0000000 0.1235753 0.1106156 0.1135736 0.1263900 972s 972s $fit 972s [1] 0.2756421 0.3165257 0.3387105 0.3466573 972s 972s $se.fit 972s [1] 0.1235753 0.1106156 0.1135736 0.1263900 972s 972s e0 eMax delta1 delta2 972s e0 0.0118410628 -0.008186899 0.003722514 -0.0008419768 972s eMax -0.0081868987 0.014334651 -0.016984400 -0.0239850502 972s delta1 0.0037225143 -0.016984400 0.475384247 0.3641344062 972s delta2 -0.0008419768 -0.023985050 0.364134406 0.3356088151 972s eMax delta1 delta2 972s eMax 0.01433465 -0.0169844 -0.02398505 972s delta1 -0.01698440 0.4753842 0.36413441 972s delta2 -0.02398505 0.3641344 0.33560882 972s Message: Setting predType to "ls-means" for "type = general" 972s Message: Setting predType to "effect-curve" for placebo-adjusted data 972s $fit 972s [1] 0.2219856 0.5065390 0.5185323 0.5721580 0.5699850 972s 972s $se.fit 972s [1] 0.1088272 0.1048057 0.1044027 0.1046862 0.1088405 972s 972s $fit 972s [1] 0.0000000 0.2845534 0.2965467 0.3501724 0.3479994 972s 972s $se.fit 972s [1] 0.0000000 0.1252903 0.1265494 0.1279290 0.1273279 972s 972s $fit 972s [1] 0.2845534 0.2965467 0.3501724 0.3479994 972s 972s $se.fit 972s [1] 0.1252903 0.1265494 0.1279290 0.1273279 972s 972s d0 d1 d2 d3 d4 972s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 972s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 972s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 972s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 972s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 972s d1 d2 d3 d4 972s d1 0.015697662 0.008221459 0.008223928 0.008215124 972s d2 0.008221459 0.016014746 0.008246506 0.008208911 972s d3 0.008223928 0.008246506 0.016365819 0.008204394 972s d4 0.008215124 0.008208911 0.008204394 0.016212400 972s d0 d1 d2 d3 d4 972s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 972s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 972s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 972s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 972s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 972s gender2 -0.005149393 -0.005062250 -0.004777264 -0.004570087 -0.005308813 972s gender2 972s d0 -0.005149393 972s d1 -0.005062250 972s d2 -0.004777264 972s d3 -0.004570087 972s d4 -0.005308813 972s gender2 0.007312139 972s d0 d1 d2 d3 d4 972s d0 0.00819461 0.000000000 0.000000000 0.000000000 0.0000000 972s d1 0.00000000 0.007459197 0.000000000 0.000000000 0.0000000 972s d2 0.00000000 0.000000000 0.007757564 0.000000000 0.0000000 972s d3 0.00000000 0.000000000 0.000000000 0.008080796 0.0000000 972s d4 0.00000000 0.000000000 0.000000000 0.000000000 0.0079701 972s d1 d2 d3 d4 972s d1 0.015697662 0.008221459 0.008223928 0.008215124 972s d2 0.008221459 0.016014746 0.008246506 0.008208911 972s d3 0.008223928 0.008246506 0.016365819 0.008204394 972s d4 0.008215124 0.008208911 0.008204394 0.016212400 972s $fit 972s [1] 0.2845534 0.2965467 0.3501724 0.3479994 972s 972s $se.fit 972s [1] 0.1252903 0.1265494 0.1279290 0.1273279 972s 972s testgFit.R passed 972s testplanMod.R passed 972s Loading required package: DoseFinding 973s [1] 0.5099184 973s Calculated TD - optimal design: 973s 0 18.75 973s 0.50003 0.49997 973s Calculated TD - optimal design: 973s 0 104.52 973s 0.49993 0.50006 973s [1] 0.4286171 973s Calculated TD - optimal design: 973s 0 101.57 150 973s 0.43958 0.50000 0.06041 973s Calculated TD - optimal design: 973s 0 37.29 64.44 150 973s 0.40070 0.45303 0.09933 0.04694 973s [1] 0.1853293 973s Calculated TD - optimal design: 973s 0 50.22 973s 0.5 0.5 973s Calculated TD - optimal design: 973s 0 0.49 25.2 108.07 973s 0.44787 0.47652 0.05213 0.02348 973s [1] 0.130092 973s Calculated TD - optimal design: 973s 0 27 94.89 150 973s 0.44879 0.47519 0.05121 0.02481 973s [1] 0.5013672 973s Calculated TD - optimal design: 973s 0 0.35 150 973s 0.49865 0.50000 0.00135 973s [1] 0.05572985 973s [1] 4.478701e-01 4.765233e-01 5.212994e-02 2.347673e-02 6.509032e-09 973s [1] 4.478701e-01 4.765233e-01 5.212991e-02 2.347669e-02 5.680430e-09 973s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 973s [1,] 0.246 0.142 0.122 0.000 0.000 0.241 0 0 0.249 973s [2,] 0.248 0.234 0.059 0.211 0.000 0.000 0 0 0.248 973s [3,] 0.247 0.000 0.000 0.224 0.081 0.203 0 0 0.246 973s [4,] 0.250 0.248 0.044 0.210 0.000 0.000 0 0 0.249 973s [5,] 0.250 0.248 0.191 0.064 0.000 0.000 0 0 0.247 973s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 973s [1,] 0.49 0.01 0.00 0.00 0.00 0.00 0.36 0.14 0.00 973s [2,] 0.48 0.02 0.00 0.32 0.18 0.00 0.00 0.00 0.00 973s [3,] 0.21 0.29 0.00 0.00 0.00 0.46 0.04 0.00 0.00 973s [4,] 0.50 0.00 0.49 0.01 0.00 0.00 0.00 0.00 0.00 973s [5,] 0.49 0.02 0.48 0.00 0.00 0.00 0.00 0.00 0.01 973s [1] 0.8823949 973s Calculated D - optimal design: 973s 0 1 973s 0.5 0.5 973s Calculated TD - optimal design: 973s 0 0.25 0.5 1 973s 0.48951 0.35517 0.14483 0.01049 973s testsDesign.R passed 974s Loading required package: DoseFinding 974s [1] 3714.641 974s [1] 3714.641 974s Dose Response Model 974s 974s Model: betaMod 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -23.368 -3.727 0.129 3.894 16.152 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 10.80 0.565 974s eMax 7.41 0.692 974s delta1 2.24 0.589 974s delta2 1.00 0.328 974s 974s Residual standard error: 5.64 974s Degrees of freedom: 585 974s 974s Formula: y ~ betaMod(x, e0, emax, delta1, delta2, 1.2 * max(datset$x)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s e0 10.7964 0.5653 19.098 < 2e-16 *** 974s emax 7.4106 0.6917 10.714 < 2e-16 *** 974s delta1 2.2357 0.5885 3.799 0.000161 *** 974s delta2 1.0047 0.3277 3.066 0.002271 ** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 5.637 on 585 degrees of freedom 974s 974s Number of iterations to convergence: 6 974s Achieved convergence tolerance: 4.028e-06 974s 974s e0 eMax delta1 delta2 974s e0 0.31958673 -0.28252697 0.20809234 0.09247897 974s eMax -0.28252697 0.47843297 -0.04177476 0.01244179 974s delta1 0.20809234 -0.04177476 0.34639417 0.18051781 974s delta2 0.09247897 0.01244179 0.18051781 0.10741016 974s e0 emax delta1 delta2 974s e0 0.31959066 -0.28253052 0.20808969 0.09247786 974s emax -0.28253052 0.47843381 -0.04177516 0.01244118 974s delta1 0.20808969 -0.04177516 0.34638195 0.18051234 974s delta2 0.09247786 0.01244118 0.18051234 0.10740756 974s $fit 974s [1] 6.0578751 6.8058158 7.2227652 6.0578751 3.1444084 6.8058158 7.2227652 974s [8] 3.1444084 6.0578751 0.0000000 6.0578751 6.0578751 7.2227652 3.1444084 974s [15] 0.8440180 0.0000000 6.0578751 3.1444084 3.1444084 0.0000000 7.2227652 974s [22] 0.0000000 7.2227652 6.8058158 6.8058158 3.1444084 6.8058158 6.8058158 974s [29] 3.1444084 6.0578751 7.2227652 6.8058158 3.1444084 3.1444084 3.1444084 974s [36] 0.0000000 0.0000000 3.1444084 6.8058158 3.1444084 3.1444084 0.8440180 974s [43] 3.1444084 6.0578751 3.1444084 6.0578751 0.8440180 7.2227652 0.8440180 974s [50] 0.8440180 0.0000000 7.2227652 6.8058158 6.8058158 7.2227652 3.1444084 974s [57] 7.2227652 6.8058158 0.8440180 0.8440180 3.1444084 0.0000000 7.2227652 974s [64] 6.8058158 6.8058158 6.8058158 0.0000000 7.2227652 3.1444084 6.0578751 974s [71] 0.0000000 0.8440180 0.8440180 6.8058158 3.1444084 3.1444084 6.0578751 974s [78] 0.0000000 6.0578751 6.8058158 6.8058158 3.1444084 3.1444084 3.1444084 974s [85] 3.1444084 7.2227652 6.8058158 0.8440180 0.0000000 0.8440180 7.2227652 974s [92] 6.8058158 3.1444084 7.2227652 6.0578751 6.8058158 6.0578751 6.8058158 974s [99] 6.8058158 6.8058158 3.1444084 6.0578751 6.8058158 0.0000000 6.0578751 974s [106] 6.8058158 0.0000000 6.8058158 3.1444084 3.1444084 0.8440180 6.8058158 974s [113] 6.0578751 3.1444084 0.1731496 6.0578751 6.0578751 0.0000000 6.8058158 974s [120] 0.0000000 0.0000000 6.8058158 0.1731496 0.8440180 0.0000000 6.0578751 974s [127] 6.8058158 3.1444084 6.0578751 0.8440180 6.8058158 0.8440180 7.2227652 974s [134] 6.8058158 3.1444084 6.0578751 6.8058158 7.2227652 6.8058158 0.1731496 974s [141] 6.8058158 6.8058158 0.8440180 6.8058158 6.0578751 7.2227652 6.8058158 974s [148] 3.1444084 3.1444084 0.0000000 6.0578751 3.1444084 0.0000000 3.1444084 974s [155] 6.8058158 7.2227652 6.8058158 0.0000000 0.0000000 0.8440180 3.1444084 974s [162] 0.0000000 0.1731496 3.1444084 3.1444084 6.0578751 0.0000000 0.8440180 974s [169] 0.0000000 3.1444084 3.1444084 6.0578751 6.0578751 0.0000000 7.2227652 974s [176] 0.8440180 0.0000000 6.0578751 0.0000000 7.2227652 0.0000000 3.1444084 974s [183] 6.0578751 6.0578751 3.1444084 3.1444084 0.1731496 7.2227652 3.1444084 974s [190] 0.8440180 7.2227652 7.2227652 0.8440180 0.0000000 7.2227652 3.1444084 974s [197] 7.2227652 7.2227652 0.1731496 3.1444084 0.0000000 7.2227652 3.1444084 974s [204] 6.8058158 6.8058158 7.2227652 6.8058158 7.2227652 0.8440180 6.0578751 974s [211] 3.1444084 3.1444084 3.1444084 0.0000000 0.0000000 6.0578751 6.0578751 974s [218] 3.1444084 3.1444084 0.1731496 7.2227652 7.2227652 0.0000000 0.8440180 974s [225] 7.2227652 0.8440180 3.1444084 0.8440180 0.0000000 7.2227652 3.1444084 974s [232] 6.8058158 6.8058158 3.1444084 0.8440180 6.0578751 0.8440180 0.0000000 974s [239] 0.0000000 6.8058158 7.2227652 6.8058158 6.0578751 3.1444084 7.2227652 974s [246] 6.8058158 3.1444084 7.2227652 0.8440180 0.8440180 7.2227652 6.0578751 974s [253] 0.1731496 7.2227652 6.8058158 6.8058158 7.2227652 6.8058158 6.0578751 974s [260] 6.8058158 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 0.8440180 974s [267] 6.8058158 3.1444084 3.1444084 0.8440180 3.1444084 0.8440180 0.0000000 974s [274] 3.1444084 0.8440180 0.8440180 0.1731496 6.0578751 6.0578751 0.8440180 974s [281] 0.0000000 0.0000000 0.0000000 6.0578751 0.0000000 3.1444084 3.1444084 974s [288] 0.0000000 0.8440180 6.0578751 0.0000000 6.0578751 7.2227652 0.8440180 974s [295] 7.2227652 6.8058158 0.8440180 0.1731496 7.2227652 7.2227652 0.0000000 974s [302] 6.0578751 6.8058158 7.2227652 0.0000000 6.0578751 6.0578751 6.8058158 974s [309] 0.0000000 0.8440180 6.0578751 6.8058158 6.8058158 3.1444084 0.8440180 974s [316] 6.8058158 3.1444084 7.2227652 6.0578751 0.8440180 3.1444084 0.8440180 974s [323] 7.2227652 6.0578751 6.0578751 7.2227652 3.1444084 6.0578751 6.8058158 974s [330] 0.8440180 0.8440180 6.8058158 6.8058158 7.2227652 0.8440180 3.1444084 974s [337] 3.1444084 6.0578751 6.0578751 0.0000000 3.1444084 6.8058158 0.8440180 974s [344] 3.1444084 6.0578751 7.2227652 3.1444084 3.1444084 0.1731496 6.0578751 974s [351] 7.2227652 7.2227652 3.1444084 6.0578751 3.1444084 6.0578751 3.1444084 974s [358] 6.0578751 3.1444084 7.2227652 0.8440180 3.1444084 6.8058158 0.8440180 974s [365] 3.1444084 0.1731496 6.8058158 3.1444084 6.8058158 7.2227652 3.1444084 974s [372] 6.8058158 6.8058158 3.1444084 0.0000000 0.8440180 0.8440180 6.8058158 974s [379] 0.0000000 7.2227652 0.8440180 0.8440180 6.0578751 3.1444084 0.8440180 974s [386] 7.2227652 3.1444084 7.2227652 6.8058158 3.1444084 3.1444084 6.8058158 974s [393] 6.0578751 3.1444084 6.8058158 0.0000000 6.8058158 0.8440180 0.0000000 974s [400] 3.1444084 6.8058158 0.8440180 6.0578751 6.0578751 0.1731496 6.0578751 974s [407] 0.8440180 3.1444084 0.8440180 3.1444084 3.1444084 6.8058158 0.8440180 974s [414] 6.8058158 7.2227652 0.0000000 6.8058158 0.8440180 0.0000000 7.2227652 974s [421] 6.8058158 3.1444084 3.1444084 6.8058158 6.8058158 6.0578751 6.0578751 974s [428] 6.0578751 7.2227652 0.1731496 7.2227652 6.8058158 0.0000000 3.1444084 974s [435] 7.2227652 6.8058158 6.8058158 0.8440180 0.0000000 3.1444084 7.2227652 974s [442] 6.8058158 6.0578751 3.1444084 6.0578751 7.2227652 6.0578751 7.2227652 974s [449] 0.0000000 7.2227652 7.2227652 0.8440180 6.0578751 6.8058158 0.0000000 974s [456] 0.8440180 6.0578751 0.1731496 3.1444084 7.2227652 7.2227652 6.0578751 974s [463] 6.0578751 3.1444084 0.1731496 7.2227652 6.8058158 0.8440180 0.0000000 974s [470] 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 7.2227652 0.8440180 974s [477] 3.1444084 7.2227652 7.2227652 0.1731496 3.1444084 7.2227652 7.2227652 974s [484] 3.1444084 6.8058158 0.0000000 7.2227652 6.0578751 0.8440180 3.1444084 974s [491] 7.2227652 7.2227652 6.0578751 3.1444084 7.2227652 6.0578751 0.0000000 974s [498] 0.8440180 6.0578751 6.8058158 3.1444084 6.0578751 0.0000000 7.2227652 974s [505] 3.1444084 0.0000000 0.8440180 7.2227652 6.8058158 6.8058158 3.1444084 974s [512] 6.8058158 0.1731496 0.0000000 3.1444084 3.1444084 3.1444084 6.8058158 974s [519] 6.8058158 0.0000000 6.8058158 6.8058158 3.1444084 7.2227652 3.1444084 974s [526] 0.8440180 0.8440180 7.2227652 6.0578751 6.0578751 3.1444084 6.8058158 974s [533] 7.2227652 6.0578751 6.8058158 3.1444084 3.1444084 3.1444084 7.2227652 974s [540] 0.0000000 0.0000000 6.8058158 3.1444084 0.1731496 0.0000000 6.0578751 974s [547] 7.2227652 6.0578751 6.0578751 7.2227652 6.0578751 6.0578751 6.8058158 974s [554] 0.0000000 0.0000000 3.1444084 6.0578751 7.2227652 7.2227652 3.1444084 974s [561] 3.1444084 6.8058158 7.2227652 6.8058158 6.8058158 0.0000000 6.8058158 974s [568] 3.1444084 7.2227652 0.8440180 0.0000000 3.1444084 0.8440180 6.8058158 974s [575] 7.2227652 3.1444084 6.0578751 0.8440180 6.8058158 3.1444084 0.0000000 974s [582] 7.2227652 6.8058158 0.8440180 6.0578751 3.1444084 6.8058158 0.8440180 974s [589] 6.0578751 974s 974s $se.fit 974s [1] 0.7643614 0.6580335 0.7488551 0.7643614 0.7997224 0.6580335 0.7488551 974s [8] 0.7997224 0.7643614 0.0000000 0.7643614 0.7643614 0.7488551 0.7997224 974s [15] 0.4790120 0.0000000 0.7643614 0.7997224 0.7997224 0.0000000 0.7488551 974s [22] 0.0000000 0.7488551 0.6580335 0.6580335 0.7997224 0.6580335 0.6580335 974s [29] 0.7997224 0.7643614 0.7488551 0.6580335 0.7997224 0.7997224 0.7997224 974s [36] 0.0000000 0.0000000 0.7997224 0.6580335 0.7997224 0.7997224 0.4790120 974s [43] 0.7997224 0.7643614 0.7997224 0.7643614 0.4790120 0.7488551 0.4790120 974s [50] 0.4790120 0.0000000 0.7488551 0.6580335 0.6580335 0.7488551 0.7997224 974s [57] 0.7488551 0.6580335 0.4790120 0.4790120 0.7997224 0.0000000 0.7488551 974s [64] 0.6580335 0.6580335 0.6580335 0.0000000 0.7488551 0.7997224 0.7643614 974s [71] 0.0000000 0.4790120 0.4790120 0.6580335 0.7997224 0.7997224 0.7643614 974s [78] 0.0000000 0.7643614 0.6580335 0.6580335 0.7997224 0.7997224 0.7997224 974s [85] 0.7997224 0.7488551 0.6580335 0.4790120 0.0000000 0.4790120 0.7488551 974s [92] 0.6580335 0.7997224 0.7488551 0.7643614 0.6580335 0.7643614 0.6580335 974s [99] 0.6580335 0.6580335 0.7997224 0.7643614 0.6580335 0.0000000 0.7643614 974s [106] 0.6580335 0.0000000 0.6580335 0.7997224 0.7997224 0.4790120 0.6580335 974s [113] 0.7643614 0.7997224 0.1680259 0.7643614 0.7643614 0.0000000 0.6580335 974s [120] 0.0000000 0.0000000 0.6580335 0.1680259 0.4790120 0.0000000 0.7643614 974s [127] 0.6580335 0.7997224 0.7643614 0.4790120 0.6580335 0.4790120 0.7488551 974s [134] 0.6580335 0.7997224 0.7643614 0.6580335 0.7488551 0.6580335 0.1680259 974s [141] 0.6580335 0.6580335 0.4790120 0.6580335 0.7643614 0.7488551 0.6580335 974s [148] 0.7997224 0.7997224 0.0000000 0.7643614 0.7997224 0.0000000 0.7997224 974s [155] 0.6580335 0.7488551 0.6580335 0.0000000 0.0000000 0.4790120 0.7997224 974s [162] 0.0000000 0.1680259 0.7997224 0.7997224 0.7643614 0.0000000 0.4790120 974s [169] 0.0000000 0.7997224 0.7997224 0.7643614 0.7643614 0.0000000 0.7488551 974s [176] 0.4790120 0.0000000 0.7643614 0.0000000 0.7488551 0.0000000 0.7997224 974s [183] 0.7643614 0.7643614 0.7997224 0.7997224 0.1680259 0.7488551 0.7997224 974s [190] 0.4790120 0.7488551 0.7488551 0.4790120 0.0000000 0.7488551 0.7997224 974s [197] 0.7488551 0.7488551 0.1680259 0.7997224 0.0000000 0.7488551 0.7997224 974s [204] 0.6580335 0.6580335 0.7488551 0.6580335 0.7488551 0.4790120 0.7643614 974s [211] 0.7997224 0.7997224 0.7997224 0.0000000 0.0000000 0.7643614 0.7643614 974s [218] 0.7997224 0.7997224 0.1680259 0.7488551 0.7488551 0.0000000 0.4790120 974s [225] 0.7488551 0.4790120 0.7997224 0.4790120 0.0000000 0.7488551 0.7997224 974s [232] 0.6580335 0.6580335 0.7997224 0.4790120 0.7643614 0.4790120 0.0000000 974s [239] 0.0000000 0.6580335 0.7488551 0.6580335 0.7643614 0.7997224 0.7488551 974s [246] 0.6580335 0.7997224 0.7488551 0.4790120 0.4790120 0.7488551 0.7643614 974s [253] 0.1680259 0.7488551 0.6580335 0.6580335 0.7488551 0.6580335 0.7643614 974s [260] 0.6580335 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.4790120 974s [267] 0.6580335 0.7997224 0.7997224 0.4790120 0.7997224 0.4790120 0.0000000 974s [274] 0.7997224 0.4790120 0.4790120 0.1680259 0.7643614 0.7643614 0.4790120 974s [281] 0.0000000 0.0000000 0.0000000 0.7643614 0.0000000 0.7997224 0.7997224 974s [288] 0.0000000 0.4790120 0.7643614 0.0000000 0.7643614 0.7488551 0.4790120 974s [295] 0.7488551 0.6580335 0.4790120 0.1680259 0.7488551 0.7488551 0.0000000 974s [302] 0.7643614 0.6580335 0.7488551 0.0000000 0.7643614 0.7643614 0.6580335 974s [309] 0.0000000 0.4790120 0.7643614 0.6580335 0.6580335 0.7997224 0.4790120 974s [316] 0.6580335 0.7997224 0.7488551 0.7643614 0.4790120 0.7997224 0.4790120 974s [323] 0.7488551 0.7643614 0.7643614 0.7488551 0.7997224 0.7643614 0.6580335 974s [330] 0.4790120 0.4790120 0.6580335 0.6580335 0.7488551 0.4790120 0.7997224 974s [337] 0.7997224 0.7643614 0.7643614 0.0000000 0.7997224 0.6580335 0.4790120 974s [344] 0.7997224 0.7643614 0.7488551 0.7997224 0.7997224 0.1680259 0.7643614 974s [351] 0.7488551 0.7488551 0.7997224 0.7643614 0.7997224 0.7643614 0.7997224 974s [358] 0.7643614 0.7997224 0.7488551 0.4790120 0.7997224 0.6580335 0.4790120 974s [365] 0.7997224 0.1680259 0.6580335 0.7997224 0.6580335 0.7488551 0.7997224 974s [372] 0.6580335 0.6580335 0.7997224 0.0000000 0.4790120 0.4790120 0.6580335 974s [379] 0.0000000 0.7488551 0.4790120 0.4790120 0.7643614 0.7997224 0.4790120 974s [386] 0.7488551 0.7997224 0.7488551 0.6580335 0.7997224 0.7997224 0.6580335 974s [393] 0.7643614 0.7997224 0.6580335 0.0000000 0.6580335 0.4790120 0.0000000 974s [400] 0.7997224 0.6580335 0.4790120 0.7643614 0.7643614 0.1680259 0.7643614 974s [407] 0.4790120 0.7997224 0.4790120 0.7997224 0.7997224 0.6580335 0.4790120 974s [414] 0.6580335 0.7488551 0.0000000 0.6580335 0.4790120 0.0000000 0.7488551 974s [421] 0.6580335 0.7997224 0.7997224 0.6580335 0.6580335 0.7643614 0.7643614 974s [428] 0.7643614 0.7488551 0.1680259 0.7488551 0.6580335 0.0000000 0.7997224 974s [435] 0.7488551 0.6580335 0.6580335 0.4790120 0.0000000 0.7997224 0.7488551 974s [442] 0.6580335 0.7643614 0.7997224 0.7643614 0.7488551 0.7643614 0.7488551 974s [449] 0.0000000 0.7488551 0.7488551 0.4790120 0.7643614 0.6580335 0.0000000 974s [456] 0.4790120 0.7643614 0.1680259 0.7997224 0.7488551 0.7488551 0.7643614 974s [463] 0.7643614 0.7997224 0.1680259 0.7488551 0.6580335 0.4790120 0.0000000 974s [470] 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.7488551 0.4790120 974s [477] 0.7997224 0.7488551 0.7488551 0.1680259 0.7997224 0.7488551 0.7488551 974s [484] 0.7997224 0.6580335 0.0000000 0.7488551 0.7643614 0.4790120 0.7997224 974s [491] 0.7488551 0.7488551 0.7643614 0.7997224 0.7488551 0.7643614 0.0000000 974s [498] 0.4790120 0.7643614 0.6580335 0.7997224 0.7643614 0.0000000 0.7488551 974s [505] 0.7997224 0.0000000 0.4790120 0.7488551 0.6580335 0.6580335 0.7997224 974s [512] 0.6580335 0.1680259 0.0000000 0.7997224 0.7997224 0.7997224 0.6580335 974s [519] 0.6580335 0.0000000 0.6580335 0.6580335 0.7997224 0.7488551 0.7997224 974s [526] 0.4790120 0.4790120 0.7488551 0.7643614 0.7643614 0.7997224 0.6580335 974s [533] 0.7488551 0.7643614 0.6580335 0.7997224 0.7997224 0.7997224 0.7488551 974s [540] 0.0000000 0.0000000 0.6580335 0.7997224 0.1680259 0.0000000 0.7643614 974s [547] 0.7488551 0.7643614 0.7643614 0.7488551 0.7643614 0.7643614 0.6580335 974s [554] 0.0000000 0.0000000 0.7997224 0.7643614 0.7488551 0.7488551 0.7997224 974s [561] 0.7997224 0.6580335 0.7488551 0.6580335 0.6580335 0.0000000 0.6580335 974s [568] 0.7997224 0.7488551 0.4790120 0.0000000 0.7997224 0.4790120 0.6580335 974s [575] 0.7488551 0.7997224 0.7643614 0.4790120 0.6580335 0.7997224 0.0000000 974s [582] 0.7488551 0.6580335 0.4790120 0.7643614 0.7997224 0.6580335 0.4790120 974s [589] 0.7643614 974s 974s $fit 974s [1] 16.85434 17.60229 18.01923 16.85434 13.94088 17.60229 18.01923 13.94088 974s [9] 16.85434 10.79647 16.85434 16.85434 18.01923 13.94088 11.64049 10.79647 974s [17] 16.85434 13.94088 13.94088 10.79647 18.01923 10.79647 18.01923 17.60229 974s [25] 17.60229 13.94088 17.60229 17.60229 13.94088 16.85434 18.01923 17.60229 974s [33] 13.94088 13.94088 13.94088 10.79647 10.79647 13.94088 17.60229 13.94088 974s [41] 13.94088 11.64049 13.94088 16.85434 13.94088 16.85434 11.64049 18.01923 974s [49] 11.64049 11.64049 10.79647 18.01923 17.60229 17.60229 18.01923 13.94088 974s [57] 18.01923 17.60229 11.64049 11.64049 13.94088 10.79647 18.01923 17.60229 974s [65] 17.60229 17.60229 10.79647 18.01923 13.94088 16.85434 10.79647 11.64049 974s [73] 11.64049 17.60229 13.94088 13.94088 16.85434 10.79647 16.85434 17.60229 974s [81] 17.60229 13.94088 13.94088 13.94088 13.94088 18.01923 17.60229 11.64049 974s [89] 10.79647 11.64049 18.01923 17.60229 13.94088 18.01923 16.85434 17.60229 974s [97] 16.85434 17.60229 17.60229 17.60229 13.94088 16.85434 17.60229 10.79647 974s [105] 16.85434 17.60229 10.79647 17.60229 13.94088 13.94088 11.64049 17.60229 974s [113] 16.85434 13.94088 10.96962 16.85434 16.85434 10.79647 17.60229 10.79647 974s [121] 10.79647 17.60229 10.96962 11.64049 10.79647 16.85434 17.60229 13.94088 974s [129] 16.85434 11.64049 17.60229 11.64049 18.01923 17.60229 13.94088 16.85434 974s [137] 17.60229 18.01923 17.60229 10.96962 17.60229 17.60229 11.64049 17.60229 974s [145] 16.85434 18.01923 17.60229 13.94088 13.94088 10.79647 16.85434 13.94088 974s [153] 10.79647 13.94088 17.60229 18.01923 17.60229 10.79647 10.79647 11.64049 974s [161] 13.94088 10.79647 10.96962 13.94088 13.94088 16.85434 10.79647 11.64049 974s [169] 10.79647 13.94088 13.94088 16.85434 16.85434 10.79647 18.01923 11.64049 974s [177] 10.79647 16.85434 10.79647 18.01923 10.79647 13.94088 16.85434 16.85434 974s [185] 13.94088 13.94088 10.96962 18.01923 13.94088 11.64049 18.01923 18.01923 974s [193] 11.64049 10.79647 18.01923 13.94088 18.01923 18.01923 10.96962 13.94088 974s [201] 10.79647 18.01923 13.94088 17.60229 17.60229 18.01923 17.60229 18.01923 974s [209] 11.64049 16.85434 13.94088 13.94088 13.94088 10.79647 10.79647 16.85434 974s [217] 16.85434 13.94088 13.94088 10.96962 18.01923 18.01923 10.79647 11.64049 974s [225] 18.01923 11.64049 13.94088 11.64049 10.79647 18.01923 13.94088 17.60229 974s [233] 17.60229 13.94088 11.64049 16.85434 11.64049 10.79647 10.79647 17.60229 974s [241] 18.01923 17.60229 16.85434 13.94088 18.01923 17.60229 13.94088 18.01923 974s [249] 11.64049 11.64049 18.01923 16.85434 10.96962 18.01923 17.60229 17.60229 974s [257] 18.01923 17.60229 16.85434 17.60229 11.64049 17.60229 17.60229 18.01923 974s [265] 16.85434 11.64049 17.60229 13.94088 13.94088 11.64049 13.94088 11.64049 974s [273] 10.79647 13.94088 11.64049 11.64049 10.96962 16.85434 16.85434 11.64049 974s [281] 10.79647 10.79647 10.79647 16.85434 10.79647 13.94088 13.94088 10.79647 974s [289] 11.64049 16.85434 10.79647 16.85434 18.01923 11.64049 18.01923 17.60229 974s [297] 11.64049 10.96962 18.01923 18.01923 10.79647 16.85434 17.60229 18.01923 974s [305] 10.79647 16.85434 16.85434 17.60229 10.79647 11.64049 16.85434 17.60229 974s [313] 17.60229 13.94088 11.64049 17.60229 13.94088 18.01923 16.85434 11.64049 974s [321] 13.94088 11.64049 18.01923 16.85434 16.85434 18.01923 13.94088 16.85434 974s [329] 17.60229 11.64049 11.64049 17.60229 17.60229 18.01923 11.64049 13.94088 974s [337] 13.94088 16.85434 16.85434 10.79647 13.94088 17.60229 11.64049 13.94088 974s [345] 16.85434 18.01923 13.94088 13.94088 10.96962 16.85434 18.01923 18.01923 974s [353] 13.94088 16.85434 13.94088 16.85434 13.94088 16.85434 13.94088 18.01923 974s [361] 11.64049 13.94088 17.60229 11.64049 13.94088 10.96962 17.60229 13.94088 974s [369] 17.60229 18.01923 13.94088 17.60229 17.60229 13.94088 10.79647 11.64049 974s [377] 11.64049 17.60229 10.79647 18.01923 11.64049 11.64049 16.85434 13.94088 974s [385] 11.64049 18.01923 13.94088 18.01923 17.60229 13.94088 13.94088 17.60229 974s [393] 16.85434 13.94088 17.60229 10.79647 17.60229 11.64049 10.79647 13.94088 974s [401] 17.60229 11.64049 16.85434 16.85434 10.96962 16.85434 11.64049 13.94088 974s [409] 11.64049 13.94088 13.94088 17.60229 11.64049 17.60229 18.01923 10.79647 974s [417] 17.60229 11.64049 10.79647 18.01923 17.60229 13.94088 13.94088 17.60229 974s [425] 17.60229 16.85434 16.85434 16.85434 18.01923 10.96962 18.01923 17.60229 974s [433] 10.79647 13.94088 18.01923 17.60229 17.60229 11.64049 10.79647 13.94088 974s [441] 18.01923 17.60229 16.85434 13.94088 16.85434 18.01923 16.85434 18.01923 974s [449] 10.79647 18.01923 18.01923 11.64049 16.85434 17.60229 10.79647 11.64049 974s [457] 16.85434 10.96962 13.94088 18.01923 18.01923 16.85434 16.85434 13.94088 974s [465] 10.96962 18.01923 17.60229 11.64049 10.79647 11.64049 17.60229 17.60229 974s [473] 18.01923 16.85434 18.01923 11.64049 13.94088 18.01923 18.01923 10.96962 974s [481] 13.94088 18.01923 18.01923 13.94088 17.60229 10.79647 18.01923 16.85434 974s [489] 11.64049 13.94088 18.01923 18.01923 16.85434 13.94088 18.01923 16.85434 974s [497] 10.79647 11.64049 16.85434 17.60229 13.94088 16.85434 10.79647 18.01923 974s [505] 13.94088 10.79647 11.64049 18.01923 17.60229 17.60229 13.94088 17.60229 974s [513] 10.96962 10.79647 13.94088 13.94088 13.94088 17.60229 17.60229 10.79647 974s [521] 17.60229 17.60229 13.94088 18.01923 13.94088 11.64049 11.64049 18.01923 974s [529] 16.85434 16.85434 13.94088 17.60229 18.01923 16.85434 17.60229 13.94088 974s [537] 13.94088 13.94088 18.01923 10.79647 10.79647 17.60229 13.94088 10.96962 974s [545] 10.79647 16.85434 18.01923 16.85434 16.85434 18.01923 16.85434 16.85434 974s [553] 17.60229 10.79647 10.79647 13.94088 16.85434 18.01923 18.01923 13.94088 974s [561] 13.94088 17.60229 18.01923 17.60229 17.60229 10.79647 17.60229 13.94088 974s [569] 18.01923 11.64049 10.79647 13.94088 11.64049 17.60229 18.01923 13.94088 974s [577] 16.85434 11.64049 17.60229 13.94088 10.79647 18.01923 17.60229 11.64049 974s [585] 16.85434 13.94088 17.60229 11.64049 16.85434 974s 974s $se.fit 974s [1] 0.4716508 0.3621952 0.5408090 0.4716508 0.4610877 0.3621952 0.5408090 974s [8] 0.4610877 0.4716508 0.5653200 0.4716508 0.4716508 0.5408090 0.4610877 974s [15] 0.3763389 0.5653200 0.4716508 0.4610877 0.4610877 0.5653200 0.5408090 974s [22] 0.5653200 0.5408090 0.3621952 0.3621952 0.4610877 0.3621952 0.3621952 974s [29] 0.4610877 0.4716508 0.5408090 0.3621952 0.4610877 0.4610877 0.4610877 974s [36] 0.5653200 0.5653200 0.4610877 0.3621952 0.4610877 0.4610877 0.3763389 974s [43] 0.4610877 0.4716508 0.4610877 0.4716508 0.3763389 0.5408090 0.3763389 974s [50] 0.3763389 0.5653200 0.5408090 0.3621952 0.3621952 0.5408090 0.4610877 974s [57] 0.5408090 0.3621952 0.3763389 0.3763389 0.4610877 0.5653200 0.5408090 974s [64] 0.3621952 0.3621952 0.3621952 0.5653200 0.5408090 0.4610877 0.4716508 974s [71] 0.5653200 0.3763389 0.3763389 0.3621952 0.4610877 0.4610877 0.4716508 974s [78] 0.5653200 0.4716508 0.3621952 0.3621952 0.4610877 0.4610877 0.4610877 974s [85] 0.4610877 0.5408090 0.3621952 0.3763389 0.5653200 0.3763389 0.5408090 974s [92] 0.3621952 0.4610877 0.5408090 0.4716508 0.3621952 0.4716508 0.3621952 974s [99] 0.3621952 0.3621952 0.4610877 0.4716508 0.3621952 0.5653200 0.4716508 974s [106] 0.3621952 0.5653200 0.3621952 0.4610877 0.4610877 0.3763389 0.3621952 974s [113] 0.4716508 0.4610877 0.4616804 0.4716508 0.4716508 0.5653200 0.3621952 974s [120] 0.5653200 0.5653200 0.3621952 0.4616804 0.3763389 0.5653200 0.4716508 974s [127] 0.3621952 0.4610877 0.4716508 0.3763389 0.3621952 0.3763389 0.5408090 974s [134] 0.3621952 0.4610877 0.4716508 0.3621952 0.5408090 0.3621952 0.4616804 974s [141] 0.3621952 0.3621952 0.3763389 0.3621952 0.4716508 0.5408090 0.3621952 974s [148] 0.4610877 0.4610877 0.5653200 0.4716508 0.4610877 0.5653200 0.4610877 974s [155] 0.3621952 0.5408090 0.3621952 0.5653200 0.5653200 0.3763389 0.4610877 974s [162] 0.5653200 0.4616804 0.4610877 0.4610877 0.4716508 0.5653200 0.3763389 974s [169] 0.5653200 0.4610877 0.4610877 0.4716508 0.4716508 0.5653200 0.5408090 974s [176] 0.3763389 0.5653200 0.4716508 0.5653200 0.5408090 0.5653200 0.4610877 974s [183] 0.4716508 0.4716508 0.4610877 0.4610877 0.4616804 0.5408090 0.4610877 974s [190] 0.3763389 0.5408090 0.5408090 0.3763389 0.5653200 0.5408090 0.4610877 974s [197] 0.5408090 0.5408090 0.4616804 0.4610877 0.5653200 0.5408090 0.4610877 974s [204] 0.3621952 0.3621952 0.5408090 0.3621952 0.5408090 0.3763389 0.4716508 974s [211] 0.4610877 0.4610877 0.4610877 0.5653200 0.5653200 0.4716508 0.4716508 974s [218] 0.4610877 0.4610877 0.4616804 0.5408090 0.5408090 0.5653200 0.3763389 974s [225] 0.5408090 0.3763389 0.4610877 0.3763389 0.5653200 0.5408090 0.4610877 974s [232] 0.3621952 0.3621952 0.4610877 0.3763389 0.4716508 0.3763389 0.5653200 974s [239] 0.5653200 0.3621952 0.5408090 0.3621952 0.4716508 0.4610877 0.5408090 974s [246] 0.3621952 0.4610877 0.5408090 0.3763389 0.3763389 0.5408090 0.4716508 974s [253] 0.4616804 0.5408090 0.3621952 0.3621952 0.5408090 0.3621952 0.4716508 974s [260] 0.3621952 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.3763389 974s [267] 0.3621952 0.4610877 0.4610877 0.3763389 0.4610877 0.3763389 0.5653200 974s [274] 0.4610877 0.3763389 0.3763389 0.4616804 0.4716508 0.4716508 0.3763389 974s [281] 0.5653200 0.5653200 0.5653200 0.4716508 0.5653200 0.4610877 0.4610877 974s [288] 0.5653200 0.3763389 0.4716508 0.5653200 0.4716508 0.5408090 0.3763389 974s [295] 0.5408090 0.3621952 0.3763389 0.4616804 0.5408090 0.5408090 0.5653200 974s [302] 0.4716508 0.3621952 0.5408090 0.5653200 0.4716508 0.4716508 0.3621952 974s [309] 0.5653200 0.3763389 0.4716508 0.3621952 0.3621952 0.4610877 0.3763389 974s [316] 0.3621952 0.4610877 0.5408090 0.4716508 0.3763389 0.4610877 0.3763389 974s [323] 0.5408090 0.4716508 0.4716508 0.5408090 0.4610877 0.4716508 0.3621952 974s [330] 0.3763389 0.3763389 0.3621952 0.3621952 0.5408090 0.3763389 0.4610877 974s [337] 0.4610877 0.4716508 0.4716508 0.5653200 0.4610877 0.3621952 0.3763389 974s [344] 0.4610877 0.4716508 0.5408090 0.4610877 0.4610877 0.4616804 0.4716508 974s [351] 0.5408090 0.5408090 0.4610877 0.4716508 0.4610877 0.4716508 0.4610877 974s [358] 0.4716508 0.4610877 0.5408090 0.3763389 0.4610877 0.3621952 0.3763389 974s [365] 0.4610877 0.4616804 0.3621952 0.4610877 0.3621952 0.5408090 0.4610877 974s [372] 0.3621952 0.3621952 0.4610877 0.5653200 0.3763389 0.3763389 0.3621952 974s [379] 0.5653200 0.5408090 0.3763389 0.3763389 0.4716508 0.4610877 0.3763389 974s [386] 0.5408090 0.4610877 0.5408090 0.3621952 0.4610877 0.4610877 0.3621952 974s [393] 0.4716508 0.4610877 0.3621952 0.5653200 0.3621952 0.3763389 0.5653200 974s [400] 0.4610877 0.3621952 0.3763389 0.4716508 0.4716508 0.4616804 0.4716508 974s [407] 0.3763389 0.4610877 0.3763389 0.4610877 0.4610877 0.3621952 0.3763389 974s [414] 0.3621952 0.5408090 0.5653200 0.3621952 0.3763389 0.5653200 0.5408090 974s [421] 0.3621952 0.4610877 0.4610877 0.3621952 0.3621952 0.4716508 0.4716508 974s [428] 0.4716508 0.5408090 0.4616804 0.5408090 0.3621952 0.5653200 0.4610877 974s [435] 0.5408090 0.3621952 0.3621952 0.3763389 0.5653200 0.4610877 0.5408090 974s [442] 0.3621952 0.4716508 0.4610877 0.4716508 0.5408090 0.4716508 0.5408090 974s [449] 0.5653200 0.5408090 0.5408090 0.3763389 0.4716508 0.3621952 0.5653200 974s [456] 0.3763389 0.4716508 0.4616804 0.4610877 0.5408090 0.5408090 0.4716508 974s [463] 0.4716508 0.4610877 0.4616804 0.5408090 0.3621952 0.3763389 0.5653200 974s [470] 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.5408090 0.3763389 974s [477] 0.4610877 0.5408090 0.5408090 0.4616804 0.4610877 0.5408090 0.5408090 974s [484] 0.4610877 0.3621952 0.5653200 0.5408090 0.4716508 0.3763389 0.4610877 974s [491] 0.5408090 0.5408090 0.4716508 0.4610877 0.5408090 0.4716508 0.5653200 974s [498] 0.3763389 0.4716508 0.3621952 0.4610877 0.4716508 0.5653200 0.5408090 974s [505] 0.4610877 0.5653200 0.3763389 0.5408090 0.3621952 0.3621952 0.4610877 974s [512] 0.3621952 0.4616804 0.5653200 0.4610877 0.4610877 0.4610877 0.3621952 974s [519] 0.3621952 0.5653200 0.3621952 0.3621952 0.4610877 0.5408090 0.4610877 974s [526] 0.3763389 0.3763389 0.5408090 0.4716508 0.4716508 0.4610877 0.3621952 974s [533] 0.5408090 0.4716508 0.3621952 0.4610877 0.4610877 0.4610877 0.5408090 974s [540] 0.5653200 0.5653200 0.3621952 0.4610877 0.4616804 0.5653200 0.4716508 974s [547] 0.5408090 0.4716508 0.4716508 0.5408090 0.4716508 0.4716508 0.3621952 974s [554] 0.5653200 0.5653200 0.4610877 0.4716508 0.5408090 0.5408090 0.4610877 974s [561] 0.4610877 0.3621952 0.5408090 0.3621952 0.3621952 0.5653200 0.3621952 974s [568] 0.4610877 0.5408090 0.3763389 0.5653200 0.4610877 0.3763389 0.3621952 974s [575] 0.5408090 0.4610877 0.4716508 0.3763389 0.3621952 0.4610877 0.5653200 974s [582] 0.5408090 0.3621952 0.3763389 0.4716508 0.4610877 0.3621952 0.3763389 974s [589] 0.4716508 974s 974s [1] 64.48518 974s [1] 3722.867 974s [1] 3722.867 974s Dose Response Model 974s 974s Model: betaMod 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -23.081 -4.023 0.069 3.767 16.317 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 1.02e+01 0.82024 974s eMax 7.36e+00 0.69530 974s delta1 2.25e+00 0.60058 974s delta2 1.01e+00 0.33271 974s age 5.72e-04 0.00829 974s centergreen 7.41e-01 0.73739 974s centerred 8.30e-01 0.74509 974s centersilver 7.30e-01 0.70097 974s centeryellow 6.56e-01 0.73274 974s 974s Residual standard error: 5.65 974s Degrees of freedom: 580 974s 974s Formula: y ~ cbind(XX, betaMod(x, 0, 1, delta1, delta2, scl)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s delta1 2.253e+00 6.006e-01 3.751 0.000194 *** 974s delta2 1.006e+00 3.327e-01 3.025 0.002600 ** 974s .lin.(Intercept) 1.023e+01 8.202e-01 12.470 < 2e-16 *** 974s .lin.centergreen 7.409e-01 7.374e-01 1.005 0.315410 974s .lin.centerred 8.298e-01 7.451e-01 1.114 0.265866 974s .lin.centersilver 7.301e-01 7.010e-01 1.042 0.298051 974s .lin.centeryellow 6.562e-01 7.327e-01 0.896 0.370886 974s .lin.age 5.723e-04 8.288e-03 0.069 0.944970 974s .lin7 7.357e+00 6.953e-01 10.581 < 2e-16 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 5.653 on 580 degrees of freedom 974s 974s Number of iterations to convergence: 6 974s Achieved convergence tolerance: 9.472e-06 974s 974s e0 eMax delta1 delta2 974s e0 0.672788555 -0.2729452009 2.029556e-01 8.893435e-02 974s eMax -0.272945201 0.4834404097 -4.411253e-02 1.212204e-02 974s delta1 0.202955602 -0.0441125316 3.606932e-01 1.869163e-01 974s delta2 0.088934352 0.0121220371 1.869163e-01 1.106931e-01 974s age -0.003530727 0.0001030079 4.984077e-05 7.767012e-05 974s centergreen -0.234450342 -0.0348602441 1.207912e-02 1.405608e-03 974s centerred -0.253662862 -0.0121021695 6.628052e-04 -2.474391e-03 974s centersilver -0.222055302 -0.0379891034 1.347032e-02 4.810797e-03 974s centeryellow -0.242096858 -0.0036488338 1.244170e-02 2.099443e-03 974s age centergreen centerred centersilver 974s e0 -3.530727e-03 -0.2344503416 -0.2536628616 -2.220553e-01 974s eMax 1.030079e-04 -0.0348602441 -0.0121021695 -3.798910e-02 974s delta1 4.984077e-05 0.0120791216 0.0006628052 1.347032e-02 974s delta2 7.767012e-05 0.0014056079 -0.0024743906 4.810797e-03 974s age 6.868689e-05 0.0001513555 0.0001912581 -2.484136e-05 974s centergreen 1.513555e-04 0.5437481113 0.2513884520 2.524566e-01 974s centerred 1.912581e-04 0.2513884520 0.5551521388 2.504165e-01 974s centersilver -2.484136e-05 0.2524565639 0.2504164883 4.913597e-01 974s centeryellow -1.767809e-05 0.2510775793 0.2504115027 2.500668e-01 974s centeryellow 974s e0 -2.420969e-01 974s eMax -3.648834e-03 974s delta1 1.244170e-02 974s delta2 2.099443e-03 974s age -1.767809e-05 974s centergreen 2.510776e-01 974s centerred 2.504115e-01 974s centersilver 2.500668e-01 974s centeryellow 5.369021e-01 974s delta1 delta2 .lin.(Intercept) .lin.centergreen 974s delta1 3.606961e-01 1.869176e-01 0.202956171 0.0120792615 974s delta2 1.869176e-01 1.106938e-01 0.088934648 0.0014056742 974s .lin.(Intercept) 2.029562e-01 8.893465e-02 0.672787602 -0.2344503743 974s .lin.centergreen 1.207926e-02 1.405674e-03 -0.234450374 0.5437481112 974s .lin.centerred 6.627065e-04 -2.474441e-03 -0.253662951 0.2513884457 974s .lin.centersilver 1.347037e-02 4.810825e-03 -0.222055391 0.2524565593 974s .lin.centeryellow 1.244156e-02 2.099363e-03 -0.242097015 0.2510775716 974s .lin.age 4.984142e-05 7.767047e-05 -0.003530726 0.0001513556 974s .lin7 -4.411231e-02 1.212224e-02 -0.272944309 -0.0348602205 974s .lin.centerred .lin.centersilver .lin.centeryellow 974s delta1 0.0006627065 1.347037e-02 1.244156e-02 974s delta2 -0.0024744413 4.810825e-03 2.099363e-03 974s .lin.(Intercept) -0.2536629506 -2.220554e-01 -2.420970e-01 974s .lin.centergreen 0.2513884457 2.524566e-01 2.510776e-01 974s .lin.centerred 0.5551521364 2.504165e-01 2.504115e-01 974s .lin.centersilver 0.2504164813 4.913597e-01 2.500668e-01 974s .lin.centeryellow 0.2504114958 2.500668e-01 5.369021e-01 974s .lin.age 0.0001912581 -2.484131e-05 -1.767806e-05 974s .lin7 -0.0121021533 -3.798904e-02 -3.648777e-03 974s .lin.age .lin7 974s delta1 4.984142e-05 -0.0441123055 974s delta2 7.767047e-05 0.0121222432 974s .lin.(Intercept) -3.530726e-03 -0.2729443093 974s .lin.centergreen 1.513556e-04 -0.0348602205 974s .lin.centerred 1.912581e-04 -0.0121021533 974s .lin.centersilver -2.484131e-05 -0.0379890373 974s .lin.centeryellow -1.767806e-05 -0.0036487770 974s .lin.age 6.868689e-05 0.0001030081 974s .lin7 1.030081e-04 0.4834404337 974s $fit 974s [1] 0.000000 2.289162 974s 974s $se.fit 974s [1] 0.0000000 0.7519464 974s 974s $fit 974s [1] 10.91275 13.20191 974s 974s $se.fit 974s [1] 0.7364602 0.6423551 974s 974s [1] 65.39866 974s [1] -485.5937 974s [1] -485.5937 974s Dose Response Model 974s 974s Model: emax 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -0.0666 -0.0180 -0.0011 0.0193 0.0692 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -0.5830 6.00e-03 974s eMax 0.0163 3.36e-02 974s ed50 286.5994 1.91e+03 974s 974s Residual standard error: 0.0281 974s Degrees of freedom: 111 974s 974s Formula: y ~ emax(x, e0, emax, ed50) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s e0 -0.58297 0.00600 -97.164 <2e-16 *** 974s emax 0.01632 0.03356 0.486 0.628 974s ed50 286.45918 1905.11276 0.150 0.881 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.02814 on 111 degrees of freedom 974s 974s Number of iterations to convergence: 8 974s Achieved convergence tolerance: 9.607e-06 974s 974s e0 eMax ed50 974s e0 3.599786e-05 -2.913476e-05 1.313843e+00 974s eMax -2.913476e-05 1.126946e-03 6.130311e+01 974s ed50 1.313843e+00 6.130311e+01 3.631673e+06 974s e0 emax ed50 974s e0 3.599786e-05 -2.914142e-05 1.313001e+00 974s emax -2.914142e-05 1.126323e-03 6.126673e+01 974s ed50 1.313001e+00 6.126673e+01 3.629455e+06 974s $fit 974s [1] 0.01155472 0.01155472 0.00000000 0.01155472 0.01155472 0.01155472 974s [7] 0.01056820 0.01056820 0.01056820 0.01155472 0.01239306 0.01056820 974s [13] 0.00000000 0.01239306 0.01155472 0.01056820 0.01056820 0.00000000 974s [19] 0.01155472 0.01212084 0.01212084 0.01056820 0.00000000 0.01155472 974s [25] 0.01056820 0.01056820 0.01155472 0.00000000 0.00000000 0.01155472 974s [31] 0.01056820 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 974s [37] 0.01155472 0.01212084 0.00000000 0.01155472 0.01239306 0.01155472 974s [43] 0.01056820 0.01056820 0.01155472 0.01155472 0.01155472 0.00000000 974s [49] 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 0.01239306 974s [55] 0.00000000 0.01056820 0.01155472 0.01056820 0.01239306 0.01239306 974s [61] 0.01056820 0.01239306 0.01056820 0.01155472 0.01212084 0.01155472 974s [67] 0.01056820 0.01056820 0.01239306 0.01056820 0.00000000 0.01155472 974s [73] 0.01239306 0.01155472 0.01155472 0.01056820 0.00000000 0.00000000 974s [79] 0.01155472 0.00000000 0.00000000 0.00000000 0.01155472 0.01155472 974s [85] 0.01056820 0.01056820 0.01155472 0.01056820 0.01155472 0.01155472 974s [91] 0.01212084 0.01155472 0.01212084 0.01056820 0.00000000 0.01155472 974s [97] 0.01155472 0.01056820 0.01155472 0.00000000 0.01155472 0.01155472 974s [103] 0.01056820 0.01056820 0.01056820 0.00000000 0.01155472 0.00000000 974s [109] 0.01056820 0.01056820 0.01155472 0.01056820 0.00000000 0.01056820 974s 974s $se.fit 974s [1] 0.006800657 0.006800657 0.000000000 0.006800657 0.006800657 0.006800657 974s [7] 0.007368990 0.007368990 0.007368990 0.006800657 0.008598392 0.007368990 974s [13] 0.000000000 0.008598392 0.006800657 0.007368990 0.007368990 0.000000000 974s [19] 0.006800657 0.007779856 0.007779856 0.007368990 0.000000000 0.006800657 974s [25] 0.007368990 0.007368990 0.006800657 0.000000000 0.000000000 0.006800657 974s [31] 0.007368990 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 974s [37] 0.006800657 0.007779856 0.000000000 0.006800657 0.008598392 0.006800657 974s [43] 0.007368990 0.007368990 0.006800657 0.006800657 0.006800657 0.000000000 974s [49] 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 0.008598392 974s [55] 0.000000000 0.007368990 0.006800657 0.007368990 0.008598392 0.008598392 974s [61] 0.007368990 0.008598392 0.007368990 0.006800657 0.007779856 0.006800657 974s [67] 0.007368990 0.007368990 0.008598392 0.007368990 0.000000000 0.006800657 974s [73] 0.008598392 0.006800657 0.006800657 0.007368990 0.000000000 0.000000000 974s [79] 0.006800657 0.000000000 0.000000000 0.000000000 0.006800657 0.006800657 974s [85] 0.007368990 0.007368990 0.006800657 0.007368990 0.006800657 0.006800657 974s [91] 0.007779856 0.006800657 0.007779856 0.007368990 0.000000000 0.006800657 974s [97] 0.006800657 0.007368990 0.006800657 0.000000000 0.006800657 0.006800657 974s [103] 0.007368990 0.007368990 0.007368990 0.000000000 0.006800657 0.000000000 974s [109] 0.007368990 0.007368990 0.006800657 0.007368990 0.000000000 0.007368990 974s 974s $fit 974s [1] -0.5714146 -0.5714146 -0.5829694 -0.5714146 -0.5714146 -0.5714146 974s [7] -0.5724012 -0.5724012 -0.5724012 -0.5714146 -0.5705763 -0.5724012 974s [13] -0.5829694 -0.5705763 -0.5714146 -0.5724012 -0.5724012 -0.5829694 974s [19] -0.5714146 -0.5708485 -0.5708485 -0.5724012 -0.5829694 -0.5714146 974s [25] -0.5724012 -0.5724012 -0.5714146 -0.5829694 -0.5829694 -0.5714146 974s [31] -0.5724012 -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 974s [37] -0.5714146 -0.5708485 -0.5829694 -0.5714146 -0.5705763 -0.5714146 974s [43] -0.5724012 -0.5724012 -0.5714146 -0.5714146 -0.5714146 -0.5829694 974s [49] -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 -0.5705763 974s [55] -0.5829694 -0.5724012 -0.5714146 -0.5724012 -0.5705763 -0.5705763 974s [61] -0.5724012 -0.5705763 -0.5724012 -0.5714146 -0.5708485 -0.5714146 974s [67] -0.5724012 -0.5724012 -0.5705763 -0.5724012 -0.5829694 -0.5714146 974s [73] -0.5705763 -0.5714146 -0.5714146 -0.5724012 -0.5829694 -0.5829694 974s [79] -0.5714146 -0.5829694 -0.5829694 -0.5829694 -0.5714146 -0.5714146 974s [85] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5714146 -0.5714146 974s [91] -0.5708485 -0.5714146 -0.5708485 -0.5724012 -0.5829694 -0.5714146 974s [97] -0.5714146 -0.5724012 -0.5714146 -0.5829694 -0.5714146 -0.5714146 974s [103] -0.5724012 -0.5724012 -0.5724012 -0.5829694 -0.5714146 -0.5829694 974s [109] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5829694 -0.5724012 974s 974s $se.fit 974s [1] 0.003169353 0.003169353 0.005999821 0.003169353 0.003169353 0.003169353 974s [7] 0.004290400 0.004290400 0.004290400 0.003169353 0.006190654 0.004290400 974s [13] 0.005999821 0.006190654 0.003169353 0.004290400 0.004290400 0.005999821 974s [19] 0.003169353 0.004963663 0.004963663 0.004290400 0.005999821 0.003169353 974s [25] 0.004290400 0.004290400 0.003169353 0.005999821 0.005999821 0.003169353 974s [31] 0.004290400 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 974s [37] 0.003169353 0.004963663 0.005999821 0.003169353 0.006190654 0.003169353 974s [43] 0.004290400 0.004290400 0.003169353 0.003169353 0.003169353 0.005999821 974s [49] 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 0.006190654 974s [55] 0.005999821 0.004290400 0.003169353 0.004290400 0.006190654 0.006190654 974s [61] 0.004290400 0.006190654 0.004290400 0.003169353 0.004963663 0.003169353 974s [67] 0.004290400 0.004290400 0.006190654 0.004290400 0.005999821 0.003169353 974s [73] 0.006190654 0.003169353 0.003169353 0.004290400 0.005999821 0.005999821 974s [79] 0.003169353 0.005999821 0.005999821 0.005999821 0.003169353 0.003169353 974s [85] 0.004290400 0.004290400 0.003169353 0.004290400 0.003169353 0.003169353 974s [91] 0.004963663 0.003169353 0.004963663 0.004290400 0.005999821 0.003169353 974s [97] 0.003169353 0.004290400 0.003169353 0.005999821 0.003169353 0.003169353 974s [103] 0.004290400 0.004290400 0.004290400 0.005999821 0.003169353 0.005999821 974s [109] 0.004290400 0.004290400 0.003169353 0.004290400 0.005999821 0.004290400 974s 974s [1] 126.5178 974s [1] -481.376 974s [1] -481.378 974s Dose Response Model 974s 974s Model: emax 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -0.07408 -0.01641 -0.00232 0.01807 0.07476 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -5.81e-01 8.97e-03 974s eMax 2.93e-02 9.13e-02 974s ed50 9.03e+02 5.00e+03 974s age -1.22e-04 1.06e-04 974s centergreen 1.07e-02 8.31e-03 974s centerred 9.27e-03 7.73e-03 974s centersilver 1.22e-03 8.91e-03 974s centeryellow -4.65e-03 8.50e-03 974s 974s Residual standard error: 0.0281 974s Degrees of freedom: 106 974s 974s Formula: y ~ cbind(XX, emax(x, 0, 1, ed50)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s ed50 1.111e+03 6.451e+03 0.172 0.864 974s .lin.(Intercept) -5.813e-01 8.970e-03 -64.810 <2e-16 *** 974s .lin.centergreen 1.071e-02 8.309e-03 1.288 0.200 974s .lin.centerred 9.301e-03 7.726e-03 1.204 0.231 974s .lin.centersilver 1.196e-03 8.915e-03 0.134 0.894 974s .lin.centeryellow -4.665e-03 8.497e-03 -0.549 0.584 974s .lin.age -1.213e-04 1.057e-04 -1.148 0.254 974s .lin7 3.300e-02 1.170e-01 0.282 0.778 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.02808 on 106 degrees of freedom 974s 974s Number of iterations to convergence: 9 974s Achieved convergence tolerance: 7.028e-06 974s 974s e0 eMax ed50 age 974s e0 8.046543e-05 -3.844545e-05 2.355425e+00 -4.980066e-07 974s eMax -3.844545e-05 8.342573e-03 4.493061e+02 1.107091e-06 974s ed50 2.355425e+00 4.493061e+02 2.497229e+07 6.444381e-02 974s age -4.980066e-07 1.107091e-06 6.444381e-02 1.116195e-08 974s centergreen -1.978501e-05 6.446464e-05 4.524614e+00 -8.645567e-08 974s centerred -3.432079e-05 7.922237e-05 3.670388e+00 1.157010e-08 974s centersilver -1.753629e-05 -7.656779e-05 -3.796015e+00 -2.309374e-07 974s centeryellow -3.332560e-05 -5.044361e-05 -2.141277e+00 1.346886e-07 974s centergreen centerred centersilver centeryellow 974s e0 -1.978501e-05 -3.432079e-05 -1.753629e-05 -3.332560e-05 974s eMax 6.446464e-05 7.922237e-05 -7.656779e-05 -5.044361e-05 974s ed50 4.524614e+00 3.670388e+00 -3.796015e+00 -2.141277e+00 974s age -8.645567e-08 1.157010e-08 -2.309374e-07 1.346886e-07 974s centergreen 6.902160e-05 3.007695e-05 3.223410e-05 2.943878e-05 974s centerred 3.007695e-05 5.968790e-05 2.924362e-05 2.945739e-05 974s centersilver 3.223410e-05 2.924362e-05 7.947639e-05 2.823145e-05 974s centeryellow 2.943878e-05 2.945739e-05 2.823145e-05 7.219729e-05 974s ed50 .lin.(Intercept) .lin.centergreen 974s ed50 4.162109e+07 3.618133e+00 6.072527e+00 974s .lin.(Intercept) 3.618133e+00 8.045192e-05 -1.978784e-05 974s .lin.centergreen 6.072527e+00 -1.978784e-05 6.904772e-05 974s .lin.centerred 4.627132e+00 -3.432899e-05 3.008663e-05 974s .lin.centersilver -4.847154e+00 -1.752828e-05 3.222029e-05 974s .lin.centeryellow -2.727240e+00 -3.332482e-05 2.942341e-05 974s .lin.age 8.505295e-02 -4.980346e-07 -8.605363e-08 974s .lin7 7.456212e+02 -2.614221e-05 9.001668e-05 974s .lin.centerred .lin.centersilver .lin.centeryellow 974s ed50 4.627132e+00 -4.847154e+00 -2.727240e+00 974s .lin.(Intercept) -3.432899e-05 -1.752828e-05 -3.332482e-05 974s .lin.centergreen 3.008663e-05 3.222029e-05 2.942341e-05 974s .lin.centerred 5.968601e-05 2.924192e-05 2.945040e-05 974s .lin.centersilver 2.924192e-05 7.947836e-05 2.823890e-05 974s .lin.centeryellow 2.945040e-05 2.823890e-05 7.220391e-05 974s .lin.age 1.172543e-08 -2.311322e-07 1.344697e-07 974s .lin7 9.802604e-05 -9.643580e-05 -6.245218e-05 974s .lin.age .lin7 974s ed50 8.505295e-02 7.456212e+02 974s .lin.(Intercept) -4.980346e-07 -2.614221e-05 974s .lin.centergreen -8.605363e-08 9.001668e-05 974s .lin.centerred 1.172543e-08 9.802604e-05 974s .lin.centersilver -2.311322e-07 -9.643580e-05 974s .lin.centeryellow 1.344697e-07 -6.245218e-05 974s .lin.age 1.116761e-08 1.469361e-06 974s .lin7 1.469361e-06 1.368628e-02 974s $fit 974s [1] 0.000000000 0.002916944 974s 974s $se.fit 974s [1] 0.000000 0.005795 974s 974s $fit 974s [1] -0.5861913 -0.5832744 974s 974s $se.fit 974s [1] 0.008937545 0.009550033 974s 974s [1] 186.1323 974s [1] 2049.321 974s [1] 2049.321 974s Dose Response Model 974s 974s Model: sigEmax 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -13.6383 -2.8339 0.0791 3.0983 10.5294 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -10.92 0.555 974s eMax 17.17 3.430 974s ed50 379.22 148.679 974s h 1.38 0.349 974s 974s Residual standard error: 4.37 974s Degrees of freedom: 349 974s 974s Formula: y ~ sigEmax(x, e0, emax, ed50, h) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s e0 -10.9166 0.5552 -19.664 < 2e-16 *** 974s emax 17.1659 3.4296 5.005 8.87e-07 *** 974s ed50 379.2177 148.6773 2.551 0.0112 * 974s h 1.3754 0.3490 3.941 9.81e-05 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 4.372 on 349 degrees of freedom 974s 974s Number of iterations to convergence: 4 974s Achieved convergence tolerance: 7.009e-07 974s 974s e0 eMax ed50 h 974s e0 0.30821303 -0.518459 6.111486 0.06026433 974s eMax -0.51845900 11.762553 468.796873 -1.10430569 974s ed50 6.11148634 468.796873 22105.397044 -40.29692787 974s h 0.06026433 -1.104306 -40.296928 0.12181039 974s e0 emax ed50 h 974s e0 0.30821303 -0.5184566 6.111568 0.06026447 974s emax -0.51845655 11.7623435 468.787156 -1.10429851 974s ed50 6.11156813 468.7871558 22104.941251 -40.29652562 974s h 0.06026447 -1.1042985 -40.296526 0.12181099 974s $fit 974s [1] 12.497935 12.497935 13.842361 2.869998 13.842361 13.842361 0.000000 974s [8] 0.000000 13.842361 2.869998 12.497935 12.497935 11.114421 12.497935 974s [15] 12.497935 12.497935 12.497935 12.497935 0.000000 12.497935 12.497935 974s [22] 0.000000 13.842361 13.842361 0.000000 0.000000 2.869998 12.497935 974s [29] 2.869998 2.869998 13.842361 0.000000 11.114421 12.497935 0.000000 974s [36] 13.842361 13.842361 12.497935 13.842361 2.869998 12.497935 12.497935 974s [43] 12.497935 2.869998 12.497935 12.497935 11.114421 12.497935 13.842361 974s [50] 13.842361 12.497935 0.000000 12.497935 12.497935 0.000000 12.497935 974s [57] 0.000000 13.842361 12.497935 2.869998 12.497935 13.842361 12.497935 974s [64] 13.842361 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 974s [71] 12.497935 2.869998 12.497935 12.497935 0.000000 13.842361 0.000000 974s [78] 13.842361 12.497935 12.497935 12.497935 12.497935 13.842361 2.869998 974s [85] 12.497935 12.497935 12.497935 0.000000 0.000000 0.000000 0.000000 974s [92] 2.869998 12.497935 12.497935 2.869998 12.497935 12.497935 2.869998 974s [99] 12.497935 0.000000 12.497935 0.000000 2.869998 2.869998 2.869998 974s [106] 12.497935 13.842361 12.497935 2.869998 0.000000 13.842361 2.869998 974s [113] 12.497935 0.000000 12.497935 0.000000 13.842361 12.497935 0.000000 974s [120] 12.497935 11.114421 13.842361 12.497935 12.497935 0.000000 12.497935 974s [127] 2.869998 13.842361 12.497935 13.842361 12.497935 2.869998 12.497935 974s [134] 12.497935 12.497935 12.497935 12.497935 13.842361 13.842361 0.000000 974s [141] 11.114421 12.497935 0.000000 12.497935 13.842361 12.497935 11.114421 974s [148] 12.497935 0.000000 0.000000 2.869998 13.842361 0.000000 2.869998 974s [155] 13.842361 2.869998 11.114421 11.114421 12.497935 0.000000 12.497935 974s [162] 12.497935 2.869998 2.869998 12.497935 12.497935 12.497935 12.497935 974s [169] 2.869998 11.114421 0.000000 13.842361 12.497935 11.114421 12.497935 974s [176] 13.842361 13.842361 12.497935 12.497935 12.497935 12.497935 12.497935 974s [183] 2.869998 13.842361 0.000000 12.497935 12.497935 12.497935 2.869998 974s [190] 13.842361 12.497935 13.842361 2.869998 13.842361 12.497935 12.497935 974s [197] 12.497935 0.000000 11.114421 2.869998 12.497935 2.869998 12.497935 974s [204] 0.000000 12.497935 13.842361 12.497935 13.842361 12.497935 2.869998 974s [211] 2.869998 12.497935 13.842361 13.842361 2.869998 0.000000 13.842361 974s [218] 12.497935 12.497935 0.000000 13.842361 12.497935 12.497935 0.000000 974s [225] 13.842361 11.114421 12.497935 2.869998 12.497935 0.000000 12.497935 974s [232] 12.497935 13.842361 0.000000 12.497935 12.497935 13.842361 0.000000 974s [239] 13.842361 13.842361 12.497935 13.842361 0.000000 2.869998 12.497935 974s [246] 13.842361 12.497935 12.497935 13.842361 2.869998 0.000000 0.000000 974s [253] 11.114421 2.869998 12.497935 2.869998 13.842361 0.000000 12.497935 974s [260] 12.497935 12.497935 12.497935 11.114421 0.000000 0.000000 0.000000 974s [267] 0.000000 0.000000 0.000000 12.497935 13.842361 13.842361 2.869998 974s [274] 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 13.842361 974s [281] 12.497935 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 974s [288] 11.114421 0.000000 12.497935 12.497935 0.000000 2.869998 12.497935 974s [295] 0.000000 0.000000 13.842361 0.000000 12.497935 13.842361 12.497935 974s [302] 12.497935 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 974s [309] 11.114421 2.869998 2.869998 0.000000 13.842361 0.000000 12.497935 974s [316] 2.869998 13.842361 0.000000 13.842361 11.114421 12.497935 0.000000 974s [323] 12.497935 12.497935 0.000000 13.842361 13.842361 13.842361 13.842361 974s [330] 11.114421 2.869998 0.000000 12.497935 0.000000 12.497935 13.842361 974s [337] 12.497935 12.497935 12.497935 12.497935 12.497935 13.842361 12.497935 974s [344] 2.869998 13.842361 13.842361 2.869998 11.114421 2.869998 12.497935 974s [351] 12.497935 12.497935 13.842361 974s 974s $se.fit 974s [1] 0.6365415 0.6365415 0.7457881 0.8126372 0.7457881 0.7457881 0.0000000 974s [8] 0.0000000 0.7457881 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 974s [15] 0.6365415 0.6365415 0.6365415 0.6365415 0.0000000 0.6365415 0.6365415 974s [22] 0.0000000 0.7457881 0.7457881 0.0000000 0.0000000 0.8126372 0.6365415 974s [29] 0.8126372 0.8126372 0.7457881 0.0000000 0.8003756 0.6365415 0.0000000 974s [36] 0.7457881 0.7457881 0.6365415 0.7457881 0.8126372 0.6365415 0.6365415 974s [43] 0.6365415 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 0.7457881 974s [50] 0.7457881 0.6365415 0.0000000 0.6365415 0.6365415 0.0000000 0.6365415 974s [57] 0.0000000 0.7457881 0.6365415 0.8126372 0.6365415 0.7457881 0.6365415 974s [64] 0.7457881 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 974s [71] 0.6365415 0.8126372 0.6365415 0.6365415 0.0000000 0.7457881 0.0000000 974s [78] 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.8126372 974s [85] 0.6365415 0.6365415 0.6365415 0.0000000 0.0000000 0.0000000 0.0000000 974s [92] 0.8126372 0.6365415 0.6365415 0.8126372 0.6365415 0.6365415 0.8126372 974s [99] 0.6365415 0.0000000 0.6365415 0.0000000 0.8126372 0.8126372 0.8126372 974s [106] 0.6365415 0.7457881 0.6365415 0.8126372 0.0000000 0.7457881 0.8126372 974s [113] 0.6365415 0.0000000 0.6365415 0.0000000 0.7457881 0.6365415 0.0000000 974s [120] 0.6365415 0.8003756 0.7457881 0.6365415 0.6365415 0.0000000 0.6365415 974s [127] 0.8126372 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 0.6365415 974s [134] 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.7457881 0.0000000 974s [141] 0.8003756 0.6365415 0.0000000 0.6365415 0.7457881 0.6365415 0.8003756 974s [148] 0.6365415 0.0000000 0.0000000 0.8126372 0.7457881 0.0000000 0.8126372 974s [155] 0.7457881 0.8126372 0.8003756 0.8003756 0.6365415 0.0000000 0.6365415 974s [162] 0.6365415 0.8126372 0.8126372 0.6365415 0.6365415 0.6365415 0.6365415 974s [169] 0.8126372 0.8003756 0.0000000 0.7457881 0.6365415 0.8003756 0.6365415 974s [176] 0.7457881 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 974s [183] 0.8126372 0.7457881 0.0000000 0.6365415 0.6365415 0.6365415 0.8126372 974s [190] 0.7457881 0.6365415 0.7457881 0.8126372 0.7457881 0.6365415 0.6365415 974s [197] 0.6365415 0.0000000 0.8003756 0.8126372 0.6365415 0.8126372 0.6365415 974s [204] 0.0000000 0.6365415 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 974s [211] 0.8126372 0.6365415 0.7457881 0.7457881 0.8126372 0.0000000 0.7457881 974s [218] 0.6365415 0.6365415 0.0000000 0.7457881 0.6365415 0.6365415 0.0000000 974s [225] 0.7457881 0.8003756 0.6365415 0.8126372 0.6365415 0.0000000 0.6365415 974s [232] 0.6365415 0.7457881 0.0000000 0.6365415 0.6365415 0.7457881 0.0000000 974s [239] 0.7457881 0.7457881 0.6365415 0.7457881 0.0000000 0.8126372 0.6365415 974s [246] 0.7457881 0.6365415 0.6365415 0.7457881 0.8126372 0.0000000 0.0000000 974s [253] 0.8003756 0.8126372 0.6365415 0.8126372 0.7457881 0.0000000 0.6365415 974s [260] 0.6365415 0.6365415 0.6365415 0.8003756 0.0000000 0.0000000 0.0000000 974s [267] 0.0000000 0.0000000 0.0000000 0.6365415 0.7457881 0.7457881 0.8126372 974s [274] 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 0.7457881 974s [281] 0.6365415 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 974s [288] 0.8003756 0.0000000 0.6365415 0.6365415 0.0000000 0.8126372 0.6365415 974s [295] 0.0000000 0.0000000 0.7457881 0.0000000 0.6365415 0.7457881 0.6365415 974s [302] 0.6365415 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 974s [309] 0.8003756 0.8126372 0.8126372 0.0000000 0.7457881 0.0000000 0.6365415 974s [316] 0.8126372 0.7457881 0.0000000 0.7457881 0.8003756 0.6365415 0.0000000 974s [323] 0.6365415 0.6365415 0.0000000 0.7457881 0.7457881 0.7457881 0.7457881 974s [330] 0.8003756 0.8126372 0.0000000 0.6365415 0.0000000 0.6365415 0.7457881 974s [337] 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.6365415 974s [344] 0.8126372 0.7457881 0.7457881 0.8126372 0.8003756 0.8126372 0.6365415 974s [351] 0.6365415 0.6365415 0.7457881 974s 974s $fit 974s [1] 1.5813420 1.5813420 2.9257679 -8.0465953 2.9257679 2.9257679 974s [7] -10.9165932 -10.9165932 2.9257679 -8.0465953 1.5813420 1.5813420 974s [13] 0.1978277 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 974s [19] -10.9165932 1.5813420 1.5813420 -10.9165932 2.9257679 2.9257679 974s [25] -10.9165932 -10.9165932 -8.0465953 1.5813420 -8.0465953 -8.0465953 974s [31] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 2.9257679 974s [37] 2.9257679 1.5813420 2.9257679 -8.0465953 1.5813420 1.5813420 974s [43] 1.5813420 -8.0465953 1.5813420 1.5813420 0.1978277 1.5813420 974s [49] 2.9257679 2.9257679 1.5813420 -10.9165932 1.5813420 1.5813420 974s [55] -10.9165932 1.5813420 -10.9165932 2.9257679 1.5813420 -8.0465953 974s [61] 1.5813420 2.9257679 1.5813420 2.9257679 2.9257679 1.5813420 974s [67] 1.5813420 -8.0465953 1.5813420 -8.0465953 1.5813420 -8.0465953 974s [73] 1.5813420 1.5813420 -10.9165932 2.9257679 -10.9165932 2.9257679 974s [79] 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 -8.0465953 974s [85] 1.5813420 1.5813420 1.5813420 -10.9165932 -10.9165932 -10.9165932 974s [91] -10.9165932 -8.0465953 1.5813420 1.5813420 -8.0465953 1.5813420 974s [97] 1.5813420 -8.0465953 1.5813420 -10.9165932 1.5813420 -10.9165932 974s [103] -8.0465953 -8.0465953 -8.0465953 1.5813420 2.9257679 1.5813420 974s [109] -8.0465953 -10.9165932 2.9257679 -8.0465953 1.5813420 -10.9165932 974s [115] 1.5813420 -10.9165932 2.9257679 1.5813420 -10.9165932 1.5813420 974s [121] 0.1978277 2.9257679 1.5813420 1.5813420 -10.9165932 1.5813420 974s [127] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 974s [133] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 974s [139] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 1.5813420 974s [145] 2.9257679 1.5813420 0.1978277 1.5813420 -10.9165932 -10.9165932 974s [151] -8.0465953 2.9257679 -10.9165932 -8.0465953 2.9257679 -8.0465953 974s [157] 0.1978277 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 974s [163] -8.0465953 -8.0465953 1.5813420 1.5813420 1.5813420 1.5813420 974s [169] -8.0465953 0.1978277 -10.9165932 2.9257679 1.5813420 0.1978277 974s [175] 1.5813420 2.9257679 2.9257679 1.5813420 1.5813420 1.5813420 974s [181] 1.5813420 1.5813420 -8.0465953 2.9257679 -10.9165932 1.5813420 974s [187] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 2.9257679 974s [193] -8.0465953 2.9257679 1.5813420 1.5813420 1.5813420 -10.9165932 974s [199] 0.1978277 -8.0465953 1.5813420 -8.0465953 1.5813420 -10.9165932 974s [205] 1.5813420 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 974s [211] -8.0465953 1.5813420 2.9257679 2.9257679 -8.0465953 -10.9165932 974s [217] 2.9257679 1.5813420 1.5813420 -10.9165932 2.9257679 1.5813420 974s [223] 1.5813420 -10.9165932 2.9257679 0.1978277 1.5813420 -8.0465953 974s [229] 1.5813420 -10.9165932 1.5813420 1.5813420 2.9257679 -10.9165932 974s [235] 1.5813420 1.5813420 2.9257679 -10.9165932 2.9257679 2.9257679 974s [241] 1.5813420 2.9257679 -10.9165932 -8.0465953 1.5813420 2.9257679 974s [247] 1.5813420 1.5813420 2.9257679 -8.0465953 -10.9165932 -10.9165932 974s [253] 0.1978277 -8.0465953 1.5813420 -8.0465953 2.9257679 -10.9165932 974s [259] 1.5813420 1.5813420 1.5813420 1.5813420 0.1978277 -10.9165932 974s [265] -10.9165932 -10.9165932 -10.9165932 -10.9165932 -10.9165932 1.5813420 974s [271] 2.9257679 2.9257679 -8.0465953 1.5813420 1.5813420 1.5813420 974s [277] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 1.5813420 974s [283] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 0.1978277 974s [289] -10.9165932 1.5813420 1.5813420 -10.9165932 -8.0465953 1.5813420 974s [295] -10.9165932 -10.9165932 2.9257679 -10.9165932 1.5813420 2.9257679 974s [301] 1.5813420 1.5813420 2.9257679 1.5813420 1.5813420 -8.0465953 974s [307] 1.5813420 -8.0465953 0.1978277 -8.0465953 -8.0465953 -10.9165932 974s [313] 2.9257679 -10.9165932 1.5813420 -8.0465953 2.9257679 -10.9165932 974s [319] 2.9257679 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 974s [325] -10.9165932 2.9257679 2.9257679 2.9257679 2.9257679 0.1978277 974s [331] -8.0465953 -10.9165932 1.5813420 -10.9165932 1.5813420 2.9257679 974s [337] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 974s [343] 1.5813420 -8.0465953 2.9257679 2.9257679 -8.0465953 0.1978277 974s [349] -8.0465953 1.5813420 1.5813420 1.5813420 2.9257679 974s 974s $se.fit 974s [1] 0.3179632 0.3179632 0.4944930 0.5940988 0.4944930 0.4944930 0.5551694 974s [8] 0.5551694 0.4944930 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 974s [15] 0.3179632 0.3179632 0.3179632 0.3179632 0.5551694 0.3179632 0.3179632 974s [22] 0.5551694 0.4944930 0.4944930 0.5551694 0.5551694 0.5940988 0.3179632 974s [29] 0.5940988 0.5940988 0.4944930 0.5551694 0.5590023 0.3179632 0.5551694 974s [36] 0.4944930 0.4944930 0.3179632 0.4944930 0.5940988 0.3179632 0.3179632 974s [43] 0.3179632 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 0.4944930 974s [50] 0.4944930 0.3179632 0.5551694 0.3179632 0.3179632 0.5551694 0.3179632 974s [57] 0.5551694 0.4944930 0.3179632 0.5940988 0.3179632 0.4944930 0.3179632 974s [64] 0.4944930 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 974s [71] 0.3179632 0.5940988 0.3179632 0.3179632 0.5551694 0.4944930 0.5551694 974s [78] 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.5940988 974s [85] 0.3179632 0.3179632 0.3179632 0.5551694 0.5551694 0.5551694 0.5551694 974s [92] 0.5940988 0.3179632 0.3179632 0.5940988 0.3179632 0.3179632 0.5940988 974s [99] 0.3179632 0.5551694 0.3179632 0.5551694 0.5940988 0.5940988 0.5940988 974s [106] 0.3179632 0.4944930 0.3179632 0.5940988 0.5551694 0.4944930 0.5940988 974s [113] 0.3179632 0.5551694 0.3179632 0.5551694 0.4944930 0.3179632 0.5551694 974s [120] 0.3179632 0.5590023 0.4944930 0.3179632 0.3179632 0.5551694 0.3179632 974s [127] 0.5940988 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 0.3179632 974s [134] 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.4944930 0.5551694 974s [141] 0.5590023 0.3179632 0.5551694 0.3179632 0.4944930 0.3179632 0.5590023 974s [148] 0.3179632 0.5551694 0.5551694 0.5940988 0.4944930 0.5551694 0.5940988 974s [155] 0.4944930 0.5940988 0.5590023 0.5590023 0.3179632 0.5551694 0.3179632 974s [162] 0.3179632 0.5940988 0.5940988 0.3179632 0.3179632 0.3179632 0.3179632 974s [169] 0.5940988 0.5590023 0.5551694 0.4944930 0.3179632 0.5590023 0.3179632 974s [176] 0.4944930 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 974s [183] 0.5940988 0.4944930 0.5551694 0.3179632 0.3179632 0.3179632 0.5940988 974s [190] 0.4944930 0.3179632 0.4944930 0.5940988 0.4944930 0.3179632 0.3179632 974s [197] 0.3179632 0.5551694 0.5590023 0.5940988 0.3179632 0.5940988 0.3179632 974s [204] 0.5551694 0.3179632 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 974s [211] 0.5940988 0.3179632 0.4944930 0.4944930 0.5940988 0.5551694 0.4944930 974s [218] 0.3179632 0.3179632 0.5551694 0.4944930 0.3179632 0.3179632 0.5551694 974s [225] 0.4944930 0.5590023 0.3179632 0.5940988 0.3179632 0.5551694 0.3179632 974s [232] 0.3179632 0.4944930 0.5551694 0.3179632 0.3179632 0.4944930 0.5551694 974s [239] 0.4944930 0.4944930 0.3179632 0.4944930 0.5551694 0.5940988 0.3179632 974s [246] 0.4944930 0.3179632 0.3179632 0.4944930 0.5940988 0.5551694 0.5551694 974s [253] 0.5590023 0.5940988 0.3179632 0.5940988 0.4944930 0.5551694 0.3179632 974s [260] 0.3179632 0.3179632 0.3179632 0.5590023 0.5551694 0.5551694 0.5551694 974s [267] 0.5551694 0.5551694 0.5551694 0.3179632 0.4944930 0.4944930 0.5940988 974s [274] 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 0.4944930 974s [281] 0.3179632 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 974s [288] 0.5590023 0.5551694 0.3179632 0.3179632 0.5551694 0.5940988 0.3179632 974s [295] 0.5551694 0.5551694 0.4944930 0.5551694 0.3179632 0.4944930 0.3179632 974s [302] 0.3179632 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 974s [309] 0.5590023 0.5940988 0.5940988 0.5551694 0.4944930 0.5551694 0.3179632 974s [316] 0.5940988 0.4944930 0.5551694 0.4944930 0.5590023 0.3179632 0.5551694 974s [323] 0.3179632 0.3179632 0.5551694 0.4944930 0.4944930 0.4944930 0.4944930 974s [330] 0.5590023 0.5940988 0.5551694 0.3179632 0.5551694 0.3179632 0.4944930 974s [337] 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.3179632 974s [344] 0.5940988 0.4944930 0.4944930 0.5940988 0.5590023 0.5940988 0.3179632 974s [351] 0.3179632 0.3179632 0.4944930 974s 974s [1] 50.13645 974s [1] 2052.27 974s [1] 2052.27 974s Dose Response Model 974s 974s Model: sigEmax 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -13.6642 -2.5494 -0.0589 3.1494 10.8255 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -9.3604 8.43e-01 974s eMax 18.0312 4.04e+00 974s ed50 427.8168 1.83e+02 974s h 1.3276 3.36e-01 974s age -0.0117 8.11e-03 974s centergreen -0.7488 7.57e-01 974s centerred -0.8859 7.12e-01 974s centersilver -1.4084 7.52e-01 974s centeryellow -1.4438 7.33e-01 974s 974s Residual standard error: 4.36 974s Degrees of freedom: 344 974s 974s Formula: y ~ cbind(XX, sigEmax(x, 0, 1, ed50, h)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s ed50 427.813485 182.738231 2.341 0.0198 * 974s h 1.327626 0.335875 3.953 9.38e-05 *** 974s .lin.(Intercept) -9.360422 0.842795 -11.106 < 2e-16 *** 974s .lin.centergreen -0.748766 0.757412 -0.989 0.3236 974s .lin.centerred -0.885871 0.711909 -1.244 0.2142 974s .lin.centersilver -1.408359 0.752071 -1.873 0.0620 . 974s .lin.centeryellow -1.443811 0.733469 -1.968 0.0498 * 974s .lin.age -0.011703 0.008114 -1.442 0.1501 974s .lin7 18.031101 4.042408 4.460 1.11e-05 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 4.36 on 344 degrees of freedom 974s 974s Number of iterations to convergence: 4 974s Achieved convergence tolerance: 7.015e-06 974s 974s e0 eMax ed50 h 974s e0 0.710302651 -4.248050e-01 12.9547646 5.611113e-02 974s eMax -0.424805031 1.634158e+01 694.3472385 -1.241172e+00 974s ed50 12.954764634 6.943472e+02 33394.5386095 -4.820462e+01 974s h 0.056111134 -1.241172e+00 -48.2046174 1.128111e-01 974s age -0.003282055 -7.347999e-04 -0.0251683 3.613375e-05 974s centergreen -0.239527553 2.751352e-02 1.4126289 -4.650674e-03 974s centerred -0.290825609 -1.412230e-01 -9.3345325 5.133219e-03 974s centersilver -0.296694203 -2.684223e-01 -15.5401130 1.239080e-02 974s centeryellow -0.294618448 -1.827692e-01 -11.6914478 8.045886e-03 974s age centergreen centerred centersilver 974s e0 -3.282055e-03 -0.2395275534 -2.908256e-01 -2.966942e-01 974s eMax -7.347999e-04 0.0275135152 -1.412230e-01 -2.684223e-01 974s ed50 -2.516830e-02 1.4126288560 -9.334532e+00 -1.554011e+01 974s h 3.613375e-05 -0.0046506738 5.133219e-03 1.239080e-02 974s age 6.584109e-05 -0.0004705249 3.847994e-05 1.268608e-04 974s centergreen -4.705249e-04 0.5736725480 2.674552e-01 2.669211e-01 974s centerred 3.847994e-05 0.2674552437 5.068148e-01 2.741110e-01 974s centersilver 1.268608e-04 0.2669210775 2.741110e-01 5.656114e-01 974s centeryellow 3.360823e-05 0.2672881708 2.729000e-01 2.753064e-01 974s centeryellow 974s e0 -2.946184e-01 974s eMax -1.827692e-01 974s ed50 -1.169145e+01 974s h 8.045886e-03 974s age 3.360823e-05 974s centergreen 2.672882e-01 974s centerred 2.729000e-01 974s centersilver 2.753064e-01 974s centeryellow 5.379774e-01 974s ed50 h .lin.(Intercept) .lin.centergreen 974s ed50 3.339326e+04 -4.820368e+01 12.954858536 1.4125956498 974s h -4.820368e+01 1.128119e-01 0.056111300 -0.0046506961 974s .lin.(Intercept) 1.295486e+01 5.611130e-02 0.710302646 -0.2395275486 974s .lin.centergreen 1.412596e+00 -4.650696e-03 -0.239527549 0.5736725489 974s .lin.centerred -9.334399e+00 5.133264e-03 -0.290825609 0.2674552405 974s .lin.centersilver -1.553987e+01 1.239088e-02 -0.296694200 0.2669210724 974s .lin.centeryellow -1.169127e+01 8.045945e-03 -0.294618447 0.2672881668 974s .lin.age -2.516784e-02 3.613396e-05 -0.003282055 -0.0004705249 974s .lin7 6.943216e+02 -1.241157e+00 -0.424801861 0.0275129941 974s .lin.centerred .lin.centersilver .lin.centeryellow 974s ed50 -9.334399e+00 -1.553987e+01 -1.169127e+01 974s h 5.133264e-03 1.239088e-02 8.045945e-03 974s .lin.(Intercept) -2.908256e-01 -2.966942e-01 -2.946184e-01 974s .lin.centergreen 2.674552e-01 2.669211e-01 2.672882e-01 974s .lin.centerred 5.068148e-01 2.741110e-01 2.729000e-01 974s .lin.centersilver 2.741110e-01 5.656114e-01 2.753064e-01 974s .lin.centeryellow 2.729000e-01 2.753064e-01 5.379774e-01 974s .lin.age 3.847993e-05 1.268608e-04 3.360822e-05 974s .lin7 -1.412207e-01 -2.684181e-01 -1.827662e-01 974s .lin.age .lin7 974s ed50 -2.516784e-02 694.321579932 974s h 3.613396e-05 -1.241156974 974s .lin.(Intercept) -3.282055e-03 -0.424801861 974s .lin.centergreen -4.705249e-04 0.027512994 974s .lin.centerred 3.847993e-05 -0.141220710 974s .lin.centersilver 1.268608e-04 -0.268418091 974s .lin.centeryellow 3.360822e-05 -0.182766244 974s .lin.age 6.584109e-05 -0.000734791 974s .lin7 -7.347910e-04 16.341065046 974s $fit 974s [1] 0.000000 2.286007 974s 974s $se.fit 974s [1] 0.0000000 0.7638951 974s 974s $fit 974s [1] -11.353936 -9.067928 974s 974s $se.fit 974s [1] 0.7291152 0.7547668 974s 974s [1] 50.56495 974s [1] 336.0966 974s [1] 336.0966 974s Dose Response Model 974s 974s Model: logistic 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -6.606 -1.402 -0.298 1.561 5.618 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -8.93 1.09 974s eMax 7.45 1.19 974s ed50 288.28 49.89 974s delta 43.71 37.57 974s 974s Residual standard error: 2.32 974s Degrees of freedom: 69 974s 974s Formula: y ~ logistic(x, e0, emax, ed50, delta) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s e0 -8.931 1.092 -8.179 9.42e-12 *** 974s emax 7.453 1.192 6.251 2.94e-08 *** 974s ed50 288.282 49.890 5.778 1.99e-07 *** 974s delta 43.709 37.566 1.164 0.249 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 2.323 on 69 degrees of freedom 974s 974s Number of iterations to convergence: 5 974s Achieved convergence tolerance: 1.876e-07 974s 974s e0 eMax ed50 delta 974s e0 1.192360 -1.220565 45.77140 -33.34815 974s eMax -1.220565 1.421491 -43.96678 35.28563 974s ed50 45.771405 -43.966776 2488.99412 -1733.71529 974s delta -33.348146 35.285634 -1733.71529 1411.22519 974s e0 emax ed50 delta 974s e0 1.192360 -1.220566 45.77134 -33.34807 974s emax -1.220566 1.421491 -43.96671 35.28556 974s ed50 45.771344 -43.966710 2488.98697 -1733.70785 974s delta -33.348068 35.285556 -1733.70785 1411.21841 974s $fit 974s [1] 0.0000000 5.6020564 7.4419763 7.4430636 5.6020564 0.3578039 7.4430636 974s [8] 0.3578039 7.4130064 7.4419763 5.6020564 5.6020564 5.6020564 5.6020564 974s [15] 5.6020564 5.6020564 7.4130064 0.3578039 0.3578039 7.4419763 0.3578039 974s [22] 7.4430636 0.3578039 7.4419763 7.4430636 0.3578039 7.4419763 7.4419763 974s [29] 5.6020564 0.0000000 7.4419763 5.6020564 7.4130064 7.4130064 7.4430636 974s [36] 0.0000000 7.4419763 7.4430636 5.6020564 5.6020564 5.6020564 7.4419763 974s [43] 5.6020564 0.3578039 7.4130064 5.6020564 7.4419763 0.3578039 5.6020564 974s [50] 0.0000000 5.6020564 7.4130064 7.4430636 5.6020564 0.3578039 7.4419763 974s [57] 7.4130064 7.4430636 7.4419763 7.4430636 0.0000000 5.6020564 5.6020564 974s [64] 5.6020564 7.4419763 5.6020564 7.4419763 7.4130064 7.4419763 5.6020564 974s [71] 5.6020564 0.3578039 5.6020564 974s 974s $se.fit 974s [1] 0.000000 1.134891 1.131632 1.137062 1.134891 1.244804 1.137062 1.244804 974s [9] 1.051179 1.131632 1.134891 1.134891 1.134891 1.134891 1.134891 1.134891 974s [17] 1.051179 1.244804 1.244804 1.131632 1.244804 1.137062 1.244804 1.131632 974s [25] 1.137062 1.244804 1.131632 1.131632 1.134891 0.000000 1.131632 1.134891 974s [33] 1.051179 1.051179 1.137062 0.000000 1.131632 1.137062 1.134891 1.134891 974s [41] 1.134891 1.131632 1.134891 1.244804 1.051179 1.134891 1.131632 1.244804 974s [49] 1.134891 0.000000 1.134891 1.051179 1.137062 1.134891 1.244804 1.131632 974s [57] 1.051179 1.137062 1.131632 1.137062 0.000000 1.134891 1.134891 1.134891 974s [65] 1.131632 1.134891 1.131632 1.051179 1.131632 1.134891 1.134891 1.244804 974s [73] 1.134891 974s 974s $fit 974s [1] -8.920547 -3.318491 -1.478571 -1.477483 -3.318491 -8.562743 -1.477483 974s [8] -8.562743 -1.507541 -1.478571 -3.318491 -3.318491 -3.318491 -3.318491 974s [15] -3.318491 -3.318491 -1.507541 -8.562743 -8.562743 -1.478571 -8.562743 974s [22] -1.477483 -8.562743 -1.478571 -1.477483 -8.562743 -1.478571 -1.478571 974s [29] -3.318491 -8.920547 -1.478571 -3.318491 -1.507541 -1.507541 -1.477483 974s [36] -8.920547 -1.478571 -1.477483 -3.318491 -3.318491 -3.318491 -1.478571 974s [43] -3.318491 -8.562743 -1.507541 -3.318491 -1.478571 -8.562743 -3.318491 974s [50] -8.920547 -3.318491 -1.507541 -1.477483 -3.318491 -8.562743 -1.478571 974s [57] -1.507541 -1.477483 -1.478571 -1.477483 -8.920547 -3.318491 -3.318491 974s [64] -3.318491 -1.478571 -3.318491 -1.478571 -1.507541 -1.478571 -3.318491 974s [71] -3.318491 -8.562743 -3.318491 974s 974s $se.fit 974s [1] 1.0345960 0.4644528 0.4144011 0.4155112 0.4644528 0.6986843 0.4155112 974s [8] 0.6986843 0.4088615 0.4144011 0.4644528 0.4644528 0.4644528 0.4644528 974s [15] 0.4644528 0.4644528 0.4088615 0.6986843 0.6986843 0.4144011 0.6986843 974s [22] 0.4155112 0.6986843 0.4144011 0.4155112 0.6986843 0.4144011 0.4144011 974s [29] 0.4644528 1.0345960 0.4144011 0.4644528 0.4088615 0.4088615 0.4155112 974s [36] 1.0345960 0.4144011 0.4155112 0.4644528 0.4644528 0.4644528 0.4144011 974s [43] 0.4644528 0.6986843 0.4088615 0.4644528 0.4144011 0.6986843 0.4644528 974s [50] 1.0345960 0.4644528 0.4088615 0.4155112 0.4644528 0.6986843 0.4144011 974s [57] 0.4088615 0.4155112 0.4144011 0.4155112 1.0345960 0.4644528 0.4644528 974s [64] 0.4644528 0.4144011 0.4644528 0.4144011 0.4088615 0.4144011 0.4644528 974s [71] 0.4644528 0.6986843 0.4644528 974s 974s [1] 174.1673 974s [1] 345.1575 974s [1] 345.1575 974s Dose Response Model 974s 974s Model: logistic 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -6.924 -1.388 -0.179 1.618 5.265 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -8.98657 1.419 974s eMax 7.65181 1.269 974s ed50 286.51988 50.767 974s delta 43.51040 36.726 974s age -0.00402 0.011 974s centergreen -0.12880 0.873 974s centerred 0.10022 0.975 974s centersilver 0.60689 0.985 974s centeryellow 0.06974 0.968 974s 974s Residual standard error: 2.4 974s Degrees of freedom: 64 974s 974s Formula: y ~ cbind(XX, logistic(x, 0, 1, ed50, delta)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s ed50 286.519963 50.768013 5.644 4.08e-07 *** 974s delta 43.510064 36.726739 1.185 0.241 974s .lin.(Intercept) -8.986562 1.418992 -6.333 2.71e-08 *** 974s .lin.centergreen -0.128797 0.873355 -0.147 0.883 974s .lin.centerred 0.100221 0.975122 0.103 0.918 974s .lin.centersilver 0.606894 0.985016 0.616 0.540 974s .lin.centeryellow 0.069737 0.968243 0.072 0.943 974s .lin.age -0.004017 0.011024 -0.364 0.717 974s .lin7 7.651799 1.268713 6.031 8.96e-08 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 2.396 on 64 degrees of freedom 974s 974s Number of iterations to convergence: 4 974s Achieved convergence tolerance: 6.656e-06 974s 974s e0 eMax ed50 delta 974s e0 2.013542598 -1.386381624 4.801326e+01 -3.320465e+01 974s eMax -1.386381624 1.609637809 -4.594280e+01 3.537786e+01 974s ed50 48.013263925 -45.942796986 2.577339e+03 -1.719550e+03 974s delta -33.204646034 35.377861782 -1.719550e+03 1.348832e+03 974s age -0.006268645 0.001147196 1.238916e-02 -1.182615e-04 974s centergreen -0.334052153 -0.153718220 1.779756e+00 -1.607538e+00 974s centerred -0.399667176 -0.068891593 -2.561521e+00 7.131922e-01 974s centersilver -0.538856175 0.113916607 8.446386e-02 -1.524166e+00 974s centeryellow -0.463856043 -0.044371048 -3.153773e+00 1.284203e+00 974s age centergreen centerred centersilver 974s e0 -0.0062686454 -0.3340521534 -0.399667176 -0.5388561747 974s eMax 0.0011471962 -0.1537182198 -0.068891593 0.1139166068 974s ed50 0.0123891577 1.7797560819 -2.561520564 0.0844638637 974s delta -0.0001182615 -1.6075377838 0.713192228 -1.5241663474 974s age 0.0001215321 -0.0007558322 -0.001348561 -0.0006628626 974s centergreen -0.0007558322 0.7627491953 0.499187248 0.4609636575 974s centerred -0.0013485609 0.4991872483 0.950863865 0.4738663247 974s centersilver -0.0006628626 0.4609636575 0.473866325 0.9702565708 974s centeryellow -0.0003700776 0.4923423826 0.498378928 0.4677967285 974s centeryellow 974s e0 -0.4638560434 974s eMax -0.0443710477 974s ed50 -3.1537729812 974s delta 1.2842028644 974s age -0.0003700776 974s centergreen 0.4923423826 974s centerred 0.4983789279 974s centersilver 0.4677967285 974s centeryellow 0.9374951281 974s ed50 delta .lin.(Intercept) .lin.centergreen 974s ed50 2.577391e+03 -1.719586e+03 48.013675185 1.7797792085 974s delta -1.719586e+03 1.348853e+03 -33.204886930 -1.6075529969 974s .lin.(Intercept) 4.801368e+01 -3.320489e+01 2.013538892 -0.3340522689 974s .lin.centergreen 1.779779e+00 -1.607553e+00 -0.334052269 0.7627491915 974s .lin.centerred -2.561536e+00 7.132042e-01 -0.399667184 0.4991872439 974s .lin.centersilver 8.448334e-02 -1.524165e+00 -0.538856203 0.4609636569 974s .lin.centeryellow -3.153788e+00 1.284211e+00 -0.463855840 0.4923423903 974s .lin.age 1.238909e-02 -1.181868e-04 -0.006268647 -0.0007558323 974s .lin7 -4.594320e+01 3.537808e+01 -1.386377258 -0.1537180630 974s .lin.centerred .lin.centersilver .lin.centeryellow 974s ed50 -2.561536031 0.0844833421 -3.1537878657 974s delta 0.713204179 -1.5241654679 1.2842107129 974s .lin.(Intercept) -0.399667184 -0.5388562027 -0.4638558403 974s .lin.centergreen 0.499187244 0.4609636569 0.4923423903 974s .lin.centerred 0.950863862 0.4738663195 0.4983789308 974s .lin.centersilver 0.473866320 0.9702565794 0.4677967413 974s .lin.centeryellow 0.498378931 0.4677967413 0.9374951277 974s .lin.age -0.001348561 -0.0006628628 -0.0003700776 974s .lin7 -0.068891567 0.1139166792 -0.0443712829 974s .lin.age .lin7 974s ed50 0.0123890859 -45.943204762 974s delta -0.0001181868 35.378079613 974s .lin.(Intercept) -0.0062686471 -1.386377258 974s .lin.centergreen -0.0007558323 -0.153718063 974s .lin.centerred -0.0013485609 -0.068891567 974s .lin.centersilver -0.0006628628 0.113916679 974s .lin.centeryellow -0.0003700776 -0.044371283 974s .lin.age 0.0001215321 0.001147198 974s .lin7 0.0011471982 1.609632577 974s $fit 974s [1] 0.00000000 0.09322688 974s 974s $se.fit 974s [1] 0.0000000 0.4246053 974s 974s $fit 974s [1] -8.389208 -8.295981 974s 974s $se.fit 974s [1] 1.306647 1.060317 974s 974s [1] 46.37307 974s [1] -1501.193 974s [1] -1501.193 974s Dose Response Model 974s 974s Model: exponential 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -2.70e-01 -5.95e-02 7.18e-05 5.87e-02 2.44e-01 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -0.466 6.03e-03 974s e1 0.125 9.54e-02 974s delta 972.943 4.86e+02 974s 974s Residual standard error: 0.0841 974s Degrees of freedom: 710 974s 974s Formula: y ~ exponential(x, e0, e1, delta) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s e0 -0.466094 0.006025 -77.359 <2e-16 *** 974s e1 0.124504 0.095374 1.305 0.1922 974s delta 972.943160 485.901974 2.002 0.0456 * 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.08415 on 710 degrees of freedom 974s 974s Number of iterations to convergence: 0 974s Achieved convergence tolerance: 2.866e-08 974s 974s e0 e1 delta 974s e0 3.630154e-05 -0.0004207859 -2.060286 974s e1 -4.207859e-04 0.0090961445 46.252664 974s delta -2.060286e+00 46.2526644930 236100.519975 974s e0 e1 delta 974s e0 3.630155e-05 -0.0004207863 -2.060288 974s e1 -4.207863e-04 0.0090961522 46.252705 974s delta -2.060288e+00 46.2527045249 236100.728446 974s $fit 974s [1] 0.00000000 0.03271671 0.00000000 0.11169230 0.01605388 0.18278309 974s [7] 0.18278309 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 974s [13] 0.11169230 0.01605388 0.18278309 0.18278309 0.18278309 0.18278309 974s [19] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.00000000 974s [25] 0.01605388 0.00000000 0.11169230 0.00000000 0.18278309 0.03271671 974s [31] 0.18278309 0.01605388 0.00000000 0.03271671 0.00000000 0.03271671 974s [37] 0.03271671 0.11169230 0.00000000 0.03271671 0.01605388 0.18278309 974s [43] 0.01605388 0.03271671 0.01605388 0.01605388 0.01605388 0.18278309 974s [49] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 974s [55] 0.03271671 0.03271671 0.01605388 0.00000000 0.11169230 0.18278309 974s [61] 0.00000000 0.18278309 0.18278309 0.03271671 0.03271671 0.01605388 974s [67] 0.00000000 0.03271671 0.18278309 0.01605388 0.03271671 0.00000000 974s [73] 0.00000000 0.01605388 0.18278309 0.01605388 0.00000000 0.01605388 974s [79] 0.01605388 0.01605388 0.18278309 0.18278309 0.00000000 0.01605388 974s [85] 0.11169230 0.11169230 0.01605388 0.18278309 0.11169230 0.03271671 974s [91] 0.03271671 0.18278309 0.01605388 0.11169230 0.03271671 0.00000000 974s [97] 0.18278309 0.00000000 0.00000000 0.01605388 0.11169230 0.00000000 974s [103] 0.11169230 0.03271671 0.11169230 0.18278309 0.01605388 0.00000000 974s [109] 0.11169230 0.01605388 0.11169230 0.00000000 0.00000000 0.01605388 974s [115] 0.11169230 0.01605388 0.11169230 0.11169230 0.18278309 0.01605388 974s [121] 0.11169230 0.18278309 0.00000000 0.03271671 0.18278309 0.01605388 974s [127] 0.01605388 0.03271671 0.03271671 0.11169230 0.11169230 0.18278309 974s [133] 0.00000000 0.00000000 0.01605388 0.01605388 0.01605388 0.01605388 974s [139] 0.01605388 0.18278309 0.18278309 0.01605388 0.00000000 0.18278309 974s [145] 0.00000000 0.01605388 0.18278309 0.03271671 0.18278309 0.01605388 974s [151] 0.00000000 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 974s [157] 0.01605388 0.01605388 0.00000000 0.11169230 0.00000000 0.00000000 974s [163] 0.01605388 0.03271671 0.03271671 0.00000000 0.11169230 0.18278309 974s [169] 0.18278309 0.01605388 0.03271671 0.03271671 0.11169230 0.01605388 974s [175] 0.01605388 0.03271671 0.03271671 0.00000000 0.01605388 0.01605388 974s [181] 0.11169230 0.01605388 0.03271671 0.18278309 0.11169230 0.01605388 974s [187] 0.11169230 0.03271671 0.01605388 0.03271671 0.00000000 0.18278309 974s [193] 0.03271671 0.03271671 0.01605388 0.01605388 0.01605388 0.11169230 974s [199] 0.01605388 0.00000000 0.11169230 0.11169230 0.01605388 0.03271671 974s [205] 0.00000000 0.01605388 0.00000000 0.00000000 0.01605388 0.01605388 974s [211] 0.01605388 0.03271671 0.01605388 0.03271671 0.01605388 0.18278309 974s [217] 0.01605388 0.11169230 0.01605388 0.18278309 0.11169230 0.01605388 974s [223] 0.11169230 0.18278309 0.03271671 0.18278309 0.03271671 0.11169230 974s [229] 0.11169230 0.00000000 0.01605388 0.01605388 0.11169230 0.00000000 974s [235] 0.18278309 0.03271671 0.01605388 0.11169230 0.18278309 0.18278309 974s [241] 0.01605388 0.03271671 0.00000000 0.03271671 0.18278309 0.01605388 974s [247] 0.01605388 0.03271671 0.01605388 0.11169230 0.03271671 0.03271671 974s [253] 0.11169230 0.00000000 0.00000000 0.00000000 0.01605388 0.11169230 974s [259] 0.18278309 0.01605388 0.18278309 0.01605388 0.18278309 0.03271671 974s [265] 0.01605388 0.03271671 0.01605388 0.18278309 0.18278309 0.03271671 974s [271] 0.01605388 0.18278309 0.11169230 0.01605388 0.18278309 0.01605388 974s [277] 0.01605388 0.18278309 0.11169230 0.01605388 0.18278309 0.03271671 974s [283] 0.18278309 0.01605388 0.00000000 0.01605388 0.01605388 0.01605388 974s [289] 0.11169230 0.03271671 0.03271671 0.01605388 0.03271671 0.01605388 974s [295] 0.03271671 0.00000000 0.00000000 0.01605388 0.00000000 0.01605388 974s [301] 0.11169230 0.11169230 0.18278309 0.11169230 0.01605388 0.01605388 974s [307] 0.01605388 0.03271671 0.03271671 0.03271671 0.01605388 0.18278309 974s [313] 0.03271671 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 974s [319] 0.03271671 0.11169230 0.03271671 0.01605388 0.01605388 0.01605388 974s [325] 0.18278309 0.11169230 0.01605388 0.03271671 0.18278309 0.01605388 974s [331] 0.11169230 0.03271671 0.01605388 0.03271671 0.03271671 0.01605388 974s [337] 0.01605388 0.11169230 0.01605388 0.03271671 0.01605388 0.01605388 974s [343] 0.00000000 0.01605388 0.03271671 0.01605388 0.11169230 0.18278309 974s [349] 0.01605388 0.01605388 0.01605388 0.18278309 0.11169230 0.03271671 974s [355] 0.18278309 0.01605388 0.11169230 0.03271671 0.03271671 0.01605388 974s [361] 0.01605388 0.01605388 0.01605388 0.00000000 0.03271671 0.18278309 974s [367] 0.03271671 0.18278309 0.18278309 0.01605388 0.01605388 0.11169230 974s [373] 0.01605388 0.11169230 0.01605388 0.18278309 0.18278309 0.01605388 974s [379] 0.18278309 0.18278309 0.11169230 0.11169230 0.18278309 0.03271671 974s [385] 0.18278309 0.03271671 0.18278309 0.01605388 0.11169230 0.00000000 974s [391] 0.01605388 0.00000000 0.00000000 0.01605388 0.01605388 0.03271671 974s [397] 0.03271671 0.03271671 0.00000000 0.00000000 0.01605388 0.00000000 974s [403] 0.11169230 0.03271671 0.03271671 0.00000000 0.03271671 0.01605388 974s [409] 0.01605388 0.18278309 0.03271671 0.01605388 0.03271671 0.11169230 974s [415] 0.01605388 0.11169230 0.18278309 0.11169230 0.01605388 0.03271671 974s [421] 0.01605388 0.01605388 0.18278309 0.03271671 0.11169230 0.01605388 974s [427] 0.03271671 0.00000000 0.18278309 0.01605388 0.11169230 0.01605388 974s [433] 0.01605388 0.01605388 0.00000000 0.01605388 0.11169230 0.00000000 974s [439] 0.03271671 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 974s [445] 0.00000000 0.00000000 0.01605388 0.01605388 0.00000000 0.03271671 974s [451] 0.18278309 0.01605388 0.11169230 0.00000000 0.01605388 0.00000000 974s [457] 0.01605388 0.00000000 0.18278309 0.01605388 0.01605388 0.11169230 974s [463] 0.01605388 0.03271671 0.18278309 0.18278309 0.11169230 0.18278309 974s [469] 0.01605388 0.01605388 0.00000000 0.01605388 0.01605388 0.03271671 974s [475] 0.18278309 0.03271671 0.01605388 0.18278309 0.03271671 0.11169230 974s [481] 0.00000000 0.01605388 0.18278309 0.03271671 0.01605388 0.03271671 974s [487] 0.18278309 0.11169230 0.18278309 0.01605388 0.11169230 0.18278309 974s [493] 0.11169230 0.18278309 0.03271671 0.01605388 0.18278309 0.03271671 974s [499] 0.03271671 0.01605388 0.18278309 0.11169230 0.18278309 0.18278309 974s [505] 0.01605388 0.00000000 0.01605388 0.18278309 0.18278309 0.01605388 974s [511] 0.03271671 0.01605388 0.18278309 0.01605388 0.01605388 0.03271671 974s [517] 0.01605388 0.01605388 0.03271671 0.00000000 0.03271671 0.03271671 974s [523] 0.18278309 0.03271671 0.03271671 0.03271671 0.03271671 0.00000000 974s [529] 0.01605388 0.18278309 0.03271671 0.11169230 0.18278309 0.01605388 974s [535] 0.01605388 0.01605388 0.01605388 0.11169230 0.18278309 0.00000000 974s [541] 0.03271671 0.11169230 0.03271671 0.18278309 0.03271671 0.01605388 974s [547] 0.03271671 0.00000000 0.00000000 0.18278309 0.03271671 0.11169230 974s [553] 0.11169230 0.01605388 0.00000000 0.03271671 0.00000000 0.01605388 974s [559] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.03271671 974s [565] 0.03271671 0.01605388 0.11169230 0.11169230 0.03271671 0.01605388 974s [571] 0.11169230 0.00000000 0.00000000 0.01605388 0.00000000 0.01605388 974s [577] 0.03271671 0.03271671 0.00000000 0.01605388 0.01605388 0.11169230 974s [583] 0.03271671 0.18278309 0.01605388 0.11169230 0.18278309 0.01605388 974s [589] 0.01605388 0.01605388 0.18278309 0.01605388 0.18278309 0.01605388 974s [595] 0.18278309 0.18278309 0.11169230 0.03271671 0.03271671 0.01605388 974s [601] 0.01605388 0.01605388 0.18278309 0.03271671 0.03271671 0.01605388 974s [607] 0.01605388 0.18278309 0.18278309 0.11169230 0.03271671 0.18278309 974s [613] 0.18278309 0.01605388 0.01605388 0.00000000 0.18278309 0.01605388 974s [619] 0.11169230 0.01605388 0.11169230 0.00000000 0.01605388 0.01605388 974s [625] 0.18278309 0.01605388 0.03271671 0.03271671 0.00000000 0.00000000 974s [631] 0.00000000 0.00000000 0.00000000 0.01605388 0.18278309 0.03271671 974s [637] 0.00000000 0.01605388 0.11169230 0.18278309 0.01605388 0.11169230 974s [643] 0.01605388 0.00000000 0.01605388 0.03271671 0.03271671 0.01605388 974s [649] 0.00000000 0.01605388 0.11169230 0.11169230 0.18278309 0.18278309 974s [655] 0.11169230 0.01605388 0.03271671 0.03271671 0.01605388 0.01605388 974s [661] 0.00000000 0.01605388 0.03271671 0.11169230 0.01605388 0.01605388 974s [667] 0.01605388 0.01605388 0.01605388 0.01605388 0.00000000 0.01605388 974s [673] 0.03271671 0.18278309 0.01605388 0.01605388 0.18278309 0.00000000 974s [679] 0.03271671 0.01605388 0.18278309 0.03271671 0.11169230 0.01605388 974s [685] 0.18278309 0.18278309 0.11169230 0.03271671 0.00000000 0.03271671 974s [691] 0.01605388 0.01605388 0.01605388 0.11169230 0.18278309 0.01605388 974s [697] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 974s [703] 0.11169230 0.11169230 0.01605388 0.01605388 0.01605388 0.01605388 974s [709] 0.03271671 0.11169230 0.01605388 0.18278309 0.01605388 974s 974s $se.fit 974s [1] 0.000000000 0.006873006 0.000000000 0.011203793 0.003837298 0.008771443 974s [7] 0.008771443 0.006873006 0.011203793 0.003837298 0.006873006 0.011203793 974s [13] 0.011203793 0.003837298 0.008771443 0.008771443 0.008771443 0.008771443 974s [19] 0.003837298 0.003837298 0.008771443 0.008771443 0.008771443 0.000000000 974s [25] 0.003837298 0.000000000 0.011203793 0.000000000 0.008771443 0.006873006 974s [31] 0.008771443 0.003837298 0.000000000 0.006873006 0.000000000 0.006873006 974s [37] 0.006873006 0.011203793 0.000000000 0.006873006 0.003837298 0.008771443 974s [43] 0.003837298 0.006873006 0.003837298 0.003837298 0.003837298 0.008771443 974s [49] 0.003837298 0.003837298 0.003837298 0.003837298 0.003837298 0.003837298 974s [55] 0.006873006 0.006873006 0.003837298 0.000000000 0.011203793 0.008771443 974s [61] 0.000000000 0.008771443 0.008771443 0.006873006 0.006873006 0.003837298 974s [67] 0.000000000 0.006873006 0.008771443 0.003837298 0.006873006 0.000000000 974s [73] 0.000000000 0.003837298 0.008771443 0.003837298 0.000000000 0.003837298 974s [79] 0.003837298 0.003837298 0.008771443 0.008771443 0.000000000 0.003837298 974s [85] 0.011203793 0.011203793 0.003837298 0.008771443 0.011203793 0.006873006 974s [91] 0.006873006 0.008771443 0.003837298 0.011203793 0.006873006 0.000000000 974s [97] 0.008771443 0.000000000 0.000000000 0.003837298 0.011203793 0.000000000 974s [103] 0.011203793 0.006873006 0.011203793 0.008771443 0.003837298 0.000000000 974s [109] 0.011203793 0.003837298 0.011203793 0.000000000 0.000000000 0.003837298 974s [115] 0.011203793 0.003837298 0.011203793 0.011203793 0.008771443 0.003837298 974s [121] 0.011203793 0.008771443 0.000000000 0.006873006 0.008771443 0.003837298 974s [127] 0.003837298 0.006873006 0.006873006 0.011203793 0.011203793 0.008771443 974s [133] 0.000000000 0.000000000 0.003837298 0.003837298 0.003837298 0.003837298 974s [139] 0.003837298 0.008771443 0.008771443 0.003837298 0.000000000 0.008771443 974s [145] 0.000000000 0.003837298 0.008771443 0.006873006 0.008771443 0.003837298 974s [151] 0.000000000 0.006873006 0.003837298 0.003837298 0.003837298 0.006873006 974s [157] 0.003837298 0.003837298 0.000000000 0.011203793 0.000000000 0.000000000 974s [163] 0.003837298 0.006873006 0.006873006 0.000000000 0.011203793 0.008771443 974s [169] 0.008771443 0.003837298 0.006873006 0.006873006 0.011203793 0.003837298 974s [175] 0.003837298 0.006873006 0.006873006 0.000000000 0.003837298 0.003837298 974s [181] 0.011203793 0.003837298 0.006873006 0.008771443 0.011203793 0.003837298 974s [187] 0.011203793 0.006873006 0.003837298 0.006873006 0.000000000 0.008771443 974s [193] 0.006873006 0.006873006 0.003837298 0.003837298 0.003837298 0.011203793 974s [199] 0.003837298 0.000000000 0.011203793 0.011203793 0.003837298 0.006873006 974s [205] 0.000000000 0.003837298 0.000000000 0.000000000 0.003837298 0.003837298 974s [211] 0.003837298 0.006873006 0.003837298 0.006873006 0.003837298 0.008771443 974s [217] 0.003837298 0.011203793 0.003837298 0.008771443 0.011203793 0.003837298 974s [223] 0.011203793 0.008771443 0.006873006 0.008771443 0.006873006 0.011203793 974s [229] 0.011203793 0.000000000 0.003837298 0.003837298 0.011203793 0.000000000 974s [235] 0.008771443 0.006873006 0.003837298 0.011203793 0.008771443 0.008771443 974s [241] 0.003837298 0.006873006 0.000000000 0.006873006 0.008771443 0.003837298 974s [247] 0.003837298 0.006873006 0.003837298 0.011203793 0.006873006 0.006873006 974s [253] 0.011203793 0.000000000 0.000000000 0.000000000 0.003837298 0.011203793 974s [259] 0.008771443 0.003837298 0.008771443 0.003837298 0.008771443 0.006873006 974s [265] 0.003837298 0.006873006 0.003837298 0.008771443 0.008771443 0.006873006 974s [271] 0.003837298 0.008771443 0.011203793 0.003837298 0.008771443 0.003837298 974s [277] 0.003837298 0.008771443 0.011203793 0.003837298 0.008771443 0.006873006 974s [283] 0.008771443 0.003837298 0.000000000 0.003837298 0.003837298 0.003837298 974s [289] 0.011203793 0.006873006 0.006873006 0.003837298 0.006873006 0.003837298 974s [295] 0.006873006 0.000000000 0.000000000 0.003837298 0.000000000 0.003837298 974s [301] 0.011203793 0.011203793 0.008771443 0.011203793 0.003837298 0.003837298 974s [307] 0.003837298 0.006873006 0.006873006 0.006873006 0.003837298 0.008771443 974s [313] 0.006873006 0.006873006 0.011203793 0.003837298 0.006873006 0.011203793 974s [319] 0.006873006 0.011203793 0.006873006 0.003837298 0.003837298 0.003837298 974s [325] 0.008771443 0.011203793 0.003837298 0.006873006 0.008771443 0.003837298 974s [331] 0.011203793 0.006873006 0.003837298 0.006873006 0.006873006 0.003837298 974s [337] 0.003837298 0.011203793 0.003837298 0.006873006 0.003837298 0.003837298 974s [343] 0.000000000 0.003837298 0.006873006 0.003837298 0.011203793 0.008771443 974s [349] 0.003837298 0.003837298 0.003837298 0.008771443 0.011203793 0.006873006 974s [355] 0.008771443 0.003837298 0.011203793 0.006873006 0.006873006 0.003837298 974s [361] 0.003837298 0.003837298 0.003837298 0.000000000 0.006873006 0.008771443 974s [367] 0.006873006 0.008771443 0.008771443 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974s [643] -0.4500400 -0.4660939 -0.4500400 -0.4333772 -0.4333772 -0.4500400 974s [649] -0.4660939 -0.4500400 -0.3544016 -0.3544016 -0.2833108 -0.2833108 974s [655] -0.3544016 -0.4500400 -0.4333772 -0.4333772 -0.4500400 -0.4500400 974s [661] -0.4660939 -0.4500400 -0.4333772 -0.3544016 -0.4500400 -0.4500400 974s [667] -0.4500400 -0.4500400 -0.4500400 -0.4500400 -0.4660939 -0.4500400 974s [673] -0.4333772 -0.2833108 -0.4500400 -0.4500400 -0.2833108 -0.4660939 974s [679] -0.4333772 -0.4500400 -0.2833108 -0.4333772 -0.3544016 -0.4500400 974s [685] -0.2833108 -0.2833108 -0.3544016 -0.4333772 -0.4660939 -0.4333772 974s [691] -0.4500400 -0.4500400 -0.4500400 -0.3544016 -0.2833108 -0.4500400 974s [697] -0.4500400 -0.4500400 -0.4500400 -0.4500400 -0.4500400 -0.4500400 974s [703] -0.3544016 -0.3544016 -0.4500400 -0.4500400 -0.4500400 -0.4500400 974s [709] -0.4333772 -0.3544016 -0.4500400 -0.2833108 -0.4500400 974s 974s $se.fit 974s [1] 0.006025076 0.004212735 0.006025076 0.006884091 0.003835233 0.007313632 974s [7] 0.007313632 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 974s [13] 0.006884091 0.003835233 0.007313632 0.007313632 0.007313632 0.007313632 974s [19] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.006025076 974s [25] 0.003835233 0.006025076 0.006884091 0.006025076 0.007313632 0.004212735 974s [31] 0.007313632 0.003835233 0.006025076 0.004212735 0.006025076 0.004212735 974s [37] 0.004212735 0.006884091 0.006025076 0.004212735 0.003835233 0.007313632 974s [43] 0.003835233 0.004212735 0.003835233 0.003835233 0.003835233 0.007313632 974s [49] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 974s [55] 0.004212735 0.004212735 0.003835233 0.006025076 0.006884091 0.007313632 974s [61] 0.006025076 0.007313632 0.007313632 0.004212735 0.004212735 0.003835233 974s [67] 0.006025076 0.004212735 0.007313632 0.003835233 0.004212735 0.006025076 974s [73] 0.006025076 0.003835233 0.007313632 0.003835233 0.006025076 0.003835233 974s [79] 0.003835233 0.003835233 0.007313632 0.007313632 0.006025076 0.003835233 974s [85] 0.006884091 0.006884091 0.003835233 0.007313632 0.006884091 0.004212735 974s [91] 0.004212735 0.007313632 0.003835233 0.006884091 0.004212735 0.006025076 974s [97] 0.007313632 0.006025076 0.006025076 0.003835233 0.006884091 0.006025076 974s [103] 0.006884091 0.004212735 0.006884091 0.007313632 0.003835233 0.006025076 974s [109] 0.006884091 0.003835233 0.006884091 0.006025076 0.006025076 0.003835233 974s [115] 0.006884091 0.003835233 0.006884091 0.006884091 0.007313632 0.003835233 974s [121] 0.006884091 0.007313632 0.006025076 0.004212735 0.007313632 0.003835233 974s [127] 0.003835233 0.004212735 0.004212735 0.006884091 0.006884091 0.007313632 974s [133] 0.006025076 0.006025076 0.003835233 0.003835233 0.003835233 0.003835233 974s [139] 0.003835233 0.007313632 0.007313632 0.003835233 0.006025076 0.007313632 974s [145] 0.006025076 0.003835233 0.007313632 0.004212735 0.007313632 0.003835233 974s [151] 0.006025076 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 974s [157] 0.003835233 0.003835233 0.006025076 0.006884091 0.006025076 0.006025076 974s [163] 0.003835233 0.004212735 0.004212735 0.006025076 0.006884091 0.007313632 974s [169] 0.007313632 0.003835233 0.004212735 0.004212735 0.006884091 0.003835233 974s [175] 0.003835233 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 974s [181] 0.006884091 0.003835233 0.004212735 0.007313632 0.006884091 0.003835233 974s [187] 0.006884091 0.004212735 0.003835233 0.004212735 0.006025076 0.007313632 974s [193] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.006884091 974s [199] 0.003835233 0.006025076 0.006884091 0.006884091 0.003835233 0.004212735 974s [205] 0.006025076 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 974s [211] 0.003835233 0.004212735 0.003835233 0.004212735 0.003835233 0.007313632 974s [217] 0.003835233 0.006884091 0.003835233 0.007313632 0.006884091 0.003835233 974s [223] 0.006884091 0.007313632 0.004212735 0.007313632 0.004212735 0.006884091 974s [229] 0.006884091 0.006025076 0.003835233 0.003835233 0.006884091 0.006025076 974s [235] 0.007313632 0.004212735 0.003835233 0.006884091 0.007313632 0.007313632 974s [241] 0.003835233 0.004212735 0.006025076 0.004212735 0.007313632 0.003835233 974s [247] 0.003835233 0.004212735 0.003835233 0.006884091 0.004212735 0.004212735 974s [253] 0.006884091 0.006025076 0.006025076 0.006025076 0.003835233 0.006884091 974s [259] 0.007313632 0.003835233 0.007313632 0.003835233 0.007313632 0.004212735 974s [265] 0.003835233 0.004212735 0.003835233 0.007313632 0.007313632 0.004212735 974s [271] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.003835233 974s [277] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.004212735 974s [283] 0.007313632 0.003835233 0.006025076 0.003835233 0.003835233 0.003835233 974s [289] 0.006884091 0.004212735 0.004212735 0.003835233 0.004212735 0.003835233 974s [295] 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 974s [301] 0.006884091 0.006884091 0.007313632 0.006884091 0.003835233 0.003835233 974s [307] 0.003835233 0.004212735 0.004212735 0.004212735 0.003835233 0.007313632 974s [313] 0.004212735 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 974s [319] 0.004212735 0.006884091 0.004212735 0.003835233 0.003835233 0.003835233 974s [325] 0.007313632 0.006884091 0.003835233 0.004212735 0.007313632 0.003835233 974s [331] 0.006884091 0.004212735 0.003835233 0.004212735 0.004212735 0.003835233 974s [337] 0.003835233 0.006884091 0.003835233 0.004212735 0.003835233 0.003835233 974s [343] 0.006025076 0.003835233 0.004212735 0.003835233 0.006884091 0.007313632 974s [349] 0.003835233 0.003835233 0.003835233 0.007313632 0.006884091 0.004212735 974s [355] 0.007313632 0.003835233 0.006884091 0.004212735 0.004212735 0.003835233 974s [361] 0.003835233 0.003835233 0.003835233 0.006025076 0.004212735 0.007313632 974s [367] 0.004212735 0.007313632 0.007313632 0.003835233 0.003835233 0.006884091 974s [373] 0.003835233 0.006884091 0.003835233 0.007313632 0.007313632 0.003835233 974s [379] 0.007313632 0.007313632 0.006884091 0.006884091 0.007313632 0.004212735 974s [385] 0.007313632 0.004212735 0.007313632 0.003835233 0.006884091 0.006025076 974s [391] 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 0.004212735 974s [397] 0.004212735 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 974s [403] 0.006884091 0.004212735 0.004212735 0.006025076 0.004212735 0.003835233 974s [409] 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 0.006884091 974s [415] 0.003835233 0.006884091 0.007313632 0.006884091 0.003835233 0.004212735 974s [421] 0.003835233 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 974s [427] 0.004212735 0.006025076 0.007313632 0.003835233 0.006884091 0.003835233 974s [433] 0.003835233 0.003835233 0.006025076 0.003835233 0.006884091 0.006025076 974s [439] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 974s [445] 0.006025076 0.006025076 0.003835233 0.003835233 0.006025076 0.004212735 974s [451] 0.007313632 0.003835233 0.006884091 0.006025076 0.003835233 0.006025076 974s [457] 0.003835233 0.006025076 0.007313632 0.003835233 0.003835233 0.006884091 974s [463] 0.003835233 0.004212735 0.007313632 0.007313632 0.006884091 0.007313632 974s [469] 0.003835233 0.003835233 0.006025076 0.003835233 0.003835233 0.004212735 974s [475] 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 974s [481] 0.006025076 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 974s [487] 0.007313632 0.006884091 0.007313632 0.003835233 0.006884091 0.007313632 974s [493] 0.006884091 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 974s [499] 0.004212735 0.003835233 0.007313632 0.006884091 0.007313632 0.007313632 974s [505] 0.003835233 0.006025076 0.003835233 0.007313632 0.007313632 0.003835233 974s [511] 0.004212735 0.003835233 0.007313632 0.003835233 0.003835233 0.004212735 974s [517] 0.003835233 0.003835233 0.004212735 0.006025076 0.004212735 0.004212735 974s [523] 0.007313632 0.004212735 0.004212735 0.004212735 0.004212735 0.006025076 974s [529] 0.003835233 0.007313632 0.004212735 0.006884091 0.007313632 0.003835233 974s [535] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.006025076 974s [541] 0.004212735 0.006884091 0.004212735 0.007313632 0.004212735 0.003835233 974s [547] 0.004212735 0.006025076 0.006025076 0.007313632 0.004212735 0.006884091 974s [553] 0.006884091 0.003835233 0.006025076 0.004212735 0.006025076 0.003835233 974s [559] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.004212735 974s [565] 0.004212735 0.003835233 0.006884091 0.006884091 0.004212735 0.003835233 974s [571] 0.006884091 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 974s [577] 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 0.006884091 974s [583] 0.004212735 0.007313632 0.003835233 0.006884091 0.007313632 0.003835233 974s [589] 0.003835233 0.003835233 0.007313632 0.003835233 0.007313632 0.003835233 974s [595] 0.007313632 0.007313632 0.006884091 0.004212735 0.004212735 0.003835233 974s [601] 0.003835233 0.003835233 0.007313632 0.004212735 0.004212735 0.003835233 974s [607] 0.003835233 0.007313632 0.007313632 0.006884091 0.004212735 0.007313632 974s [613] 0.007313632 0.003835233 0.003835233 0.006025076 0.007313632 0.003835233 974s [619] 0.006884091 0.003835233 0.006884091 0.006025076 0.003835233 0.003835233 974s [625] 0.007313632 0.003835233 0.004212735 0.004212735 0.006025076 0.006025076 974s [631] 0.006025076 0.006025076 0.006025076 0.003835233 0.007313632 0.004212735 974s [637] 0.006025076 0.003835233 0.006884091 0.007313632 0.003835233 0.006884091 974s [643] 0.003835233 0.006025076 0.003835233 0.004212735 0.004212735 0.003835233 974s [649] 0.006025076 0.003835233 0.006884091 0.006884091 0.007313632 0.007313632 974s [655] 0.006884091 0.003835233 0.004212735 0.004212735 0.003835233 0.003835233 974s [661] 0.006025076 0.003835233 0.004212735 0.006884091 0.003835233 0.003835233 974s [667] 0.003835233 0.003835233 0.003835233 0.003835233 0.006025076 0.003835233 974s [673] 0.004212735 0.007313632 0.003835233 0.003835233 0.007313632 0.006025076 974s [679] 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 974s [685] 0.007313632 0.007313632 0.006884091 0.004212735 0.006025076 0.004212735 974s [691] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.003835233 974s [697] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 974s [703] 0.006884091 0.006884091 0.003835233 0.003835233 0.003835233 0.003835233 974s [709] 0.004212735 0.006884091 0.003835233 0.007313632 0.003835233 974s 974s [1] 573.604 974s [1] -1502.21 974s [1] -1502.21 974s Dose Response Model 974s 974s Model: exponential 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -2.72e-01 -5.96e-02 -5.44e-06 5.59e-02 2.43e-01 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -4.57e-01 1.03e-02 974s e1 1.24e-01 9.45e-02 974s delta 9.69e+02 4.79e+02 974s age -2.46e-04 1.09e-04 974s centergreen -2.26e-03 9.93e-03 974s centerred 7.10e-03 9.88e-03 974s centersilver 1.68e-02 1.02e-02 974s centeryellow -4.45e-03 1.01e-02 974s 974s Residual standard error: 0.0838 974s Degrees of freedom: 705 974s 974s Formula: y ~ cbind(XX, exponential(x, 0, 1, delta)) 974s 974s Parameters: 974s Estimate Std. Error t value Pr(>|t|) 974s delta 9.692e+02 4.795e+02 2.021 0.0436 * 974s .lin.(Intercept) -4.574e-01 1.035e-02 -44.200 <2e-16 *** 974s .lin.centergreen -2.256e-03 9.934e-03 -0.227 0.8204 974s .lin.centerred 7.104e-03 9.875e-03 0.719 0.4721 974s .lin.centersilver 1.682e-02 1.018e-02 1.652 0.0989 . 974s .lin.centeryellow -4.446e-03 1.005e-02 -0.442 0.6584 974s .lin.age -2.463e-04 1.090e-04 -2.259 0.0242 * 974s .lin7 1.244e-01 9.455e-02 1.316 0.1886 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.0838 on 705 degrees of freedom 974s 974s Number of iterations to convergence: 7 974s Achieved convergence tolerance: 8.761e-06 974s 974s e0 e1 delta age 974s e0 1.070950e-04 -3.644584e-04 -1.760351e+00 -6.235809e-07 974s e1 -3.644584e-04 8.939486e-03 4.524835e+01 -1.892276e-07 974s delta -1.760351e+00 4.524835e+01 2.299191e+05 -9.417516e-04 974s age -6.235809e-07 -1.892276e-07 -9.417516e-04 1.188604e-08 974s centergreen -4.990019e-05 -7.223389e-05 -3.668153e-01 4.308966e-08 974s centerred -5.090480e-05 -5.257813e-05 -2.765207e-01 2.992730e-08 974s centersilver -5.269569e-05 -5.104405e-05 -2.725147e-01 5.557593e-08 974s centeryellow -5.416568e-05 -3.395837e-05 -1.820279e-01 7.695026e-08 974s centergreen centerred centersilver centeryellow 974s e0 -4.990019e-05 -5.090480e-05 -5.269569e-05 -5.416568e-05 974s e1 -7.223389e-05 -5.257813e-05 -5.104405e-05 -3.395837e-05 974s delta -3.668153e-01 -2.765207e-01 -2.725147e-01 -1.820279e-01 974s age 4.308966e-08 2.992730e-08 5.557593e-08 7.695026e-08 974s centergreen 9.869293e-05 5.105736e-05 5.114013e-05 5.107251e-05 974s centerred 5.105736e-05 9.752101e-05 5.111632e-05 5.102188e-05 974s centersilver 5.114013e-05 5.111632e-05 1.036881e-04 5.122455e-05 974s centeryellow 5.107251e-05 5.102188e-05 5.122455e-05 1.010538e-04 974s delta .lin.(Intercept) .lin.centergreen 974s delta 2.299104e+05 -1.760315e+00 -3.668084e-01 974s .lin.(Intercept) -1.760315e+00 1.070949e-04 -4.990020e-05 974s .lin.centergreen -3.668084e-01 -4.990020e-05 9.869293e-05 974s .lin.centerred -2.765154e-01 -5.090480e-05 5.105736e-05 974s .lin.centersilver -2.725097e-01 -5.269570e-05 5.114013e-05 974s .lin.centeryellow -1.820244e-01 -5.416569e-05 5.107251e-05 974s .lin.age -9.417341e-04 -6.235810e-07 4.308966e-08 974s .lin7 4.524658e+01 -3.644504e-04 -7.223243e-05 974s .lin.centerred .lin.centersilver .lin.centeryellow 974s delta -2.765154e-01 -2.725097e-01 -1.820244e-01 974s .lin.(Intercept) -5.090480e-05 -5.269570e-05 -5.416569e-05 974s .lin.centergreen 5.105736e-05 5.114013e-05 5.107251e-05 974s .lin.centerred 9.752101e-05 5.111632e-05 5.102188e-05 974s .lin.centersilver 5.111632e-05 1.036881e-04 5.122455e-05 974s .lin.centeryellow 5.102188e-05 5.122455e-05 1.010538e-04 974s .lin.age 2.992730e-08 5.557593e-08 7.695026e-08 974s .lin7 -5.257703e-05 -5.104303e-05 -3.395768e-05 974s .lin.age .lin7 974s delta -9.417341e-04 4.524658e+01 974s .lin.(Intercept) -6.235810e-07 -3.644504e-04 974s .lin.centergreen 4.308966e-08 -7.223243e-05 974s .lin.centerred 2.992730e-08 -5.257703e-05 974s .lin.centersilver 5.557593e-08 -5.104303e-05 974s .lin.centeryellow 7.695026e-08 -3.395768e-05 974s .lin.age 1.188604e-08 -1.892238e-07 974s .lin7 -1.892238e-07 8.939124e-03 974s $fit 974s [1] 0.00000000 0.01352276 974s 974s $se.fit 974s [1] 0.000000000 0.003277925 974s 974s $fit 974s [1] -0.4697265 -0.4562037 974s 974s $se.fit 974s [1] 0.008628557 0.007549824 974s 974s [1] 571.7033 974s [1] 4189.744 974s [1] 4189.744 974s Dose Response Model 974s 974s Model: linear 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -20.3923 -4.1973 -0.0226 3.8448 25.3694 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -11.2122 0.393654 974s delta 0.0136 0.000531 974s 974s Residual standard error: 6.43 974s Degrees of freedom: 636 974s 974s Call: 974s lm(formula = y ~ x, data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -25.3694 -3.8448 0.0226 4.1973 20.3923 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -1.121e+01 3.937e-01 -28.48 <2e-16 *** 974s x 1.358e-02 5.313e-04 25.57 <2e-16 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 6.433 on 636 degrees of freedom 974s Multiple R-squared: 0.5069, Adjusted R-squared: 0.5061 974s F-statistic: 653.7 on 1 and 636 DF, p-value: < 2.2e-16 974s 974s e0 delta 974s e0 0.1549638101 -1.594693e-04 974s delta -0.0001594693 2.822434e-07 974s (Intercept) x 974s (Intercept) 0.1549638101 -1.594693e-04 974s x -0.0001594693 2.822434e-07 974s $fit 974s [1] 3.382287 6.560821 12.605469 12.605469 17.251020 0.000000 0.000000 974s [8] 6.560821 17.251020 3.382287 15.892672 3.382287 0.000000 9.671438 974s [15] 15.892672 17.251020 12.605469 17.251020 3.382287 17.251020 17.251020 974s [22] 9.671438 3.382287 12.605469 0.000000 12.605469 3.382287 6.560821 974s [29] 0.000000 17.251020 0.000000 9.671438 12.605469 3.382287 3.382287 974s [36] 0.000000 0.000000 12.605469 0.000000 12.605469 0.000000 15.892672 974s [43] 12.605469 15.892672 3.382287 17.251020 17.251020 6.560821 3.382287 974s [50] 0.000000 9.671438 17.251020 15.892672 0.000000 3.382287 17.251020 974s [57] 6.560821 17.251020 0.000000 3.382287 12.605469 12.605469 0.000000 974s [64] 0.000000 15.892672 15.892672 0.000000 12.605469 15.892672 3.382287 974s [71] 15.892672 6.560821 3.382287 17.251020 12.605469 0.000000 12.605469 974s [78] 12.605469 3.382287 0.000000 0.000000 0.000000 3.382287 3.382287 974s [85] 3.382287 6.560821 3.382287 0.000000 3.382287 17.251020 6.560821 974s [92] 3.382287 17.251020 9.671438 3.382287 0.000000 3.382287 3.382287 974s [99] 12.605469 0.000000 3.382287 3.382287 12.605469 0.000000 0.000000 974s [106] 17.251020 0.000000 6.560821 15.892672 17.251020 3.382287 17.251020 974s [113] 3.382287 0.000000 0.000000 3.382287 6.560821 0.000000 6.560821 974s [120] 3.382287 0.000000 0.000000 6.560821 15.892672 12.605469 12.605469 974s [127] 0.000000 17.251020 0.000000 17.251020 3.382287 0.000000 12.605469 974s [134] 17.251020 0.000000 3.382287 0.000000 6.560821 6.560821 6.560821 974s [141] 3.382287 17.251020 0.000000 0.000000 3.382287 0.000000 15.892672 974s [148] 17.251020 3.382287 15.892672 0.000000 17.251020 6.560821 3.382287 974s [155] 12.605469 6.560821 6.560821 3.382287 3.382287 0.000000 3.382287 974s [162] 0.000000 3.382287 12.605469 3.382287 0.000000 17.251020 0.000000 974s [169] 0.000000 3.382287 17.251020 3.382287 17.251020 15.892672 6.560821 974s [176] 12.605469 3.382287 0.000000 12.605469 0.000000 12.605469 17.251020 974s [183] 12.605469 0.000000 0.000000 12.605469 3.382287 12.605469 17.251020 974s [190] 3.382287 3.382287 17.251020 3.382287 6.560821 3.382287 17.251020 974s [197] 17.251020 0.000000 12.605469 0.000000 12.605469 3.382287 6.560821 974s [204] 12.605469 12.605469 3.382287 3.382287 12.605469 17.251020 12.605469 974s [211] 3.382287 3.382287 17.251020 0.000000 6.560821 3.382287 3.382287 974s [218] 0.000000 6.560821 0.000000 6.560821 6.560821 3.382287 0.000000 974s [225] 3.382287 3.382287 17.251020 3.382287 0.000000 17.251020 3.382287 974s [232] 6.560821 17.251020 0.000000 0.000000 3.382287 3.382287 12.605469 974s [239] 6.560821 12.605469 3.382287 12.605469 17.251020 6.560821 17.251020 974s [246] 17.251020 15.892672 0.000000 3.382287 3.382287 3.382287 0.000000 974s [253] 12.605469 15.892672 6.560821 3.382287 3.382287 0.000000 0.000000 974s [260] 12.605469 6.560821 3.382287 3.382287 12.605469 17.251020 0.000000 974s [267] 6.560821 15.892672 3.382287 15.892672 3.382287 12.605469 0.000000 974s [274] 17.251020 15.892672 6.560821 3.382287 12.605469 0.000000 3.382287 974s [281] 3.382287 12.605469 3.382287 0.000000 17.251020 15.892672 17.251020 974s [288] 3.382287 17.251020 3.382287 3.382287 3.382287 15.892672 0.000000 974s [295] 0.000000 17.251020 17.251020 12.605469 0.000000 12.605469 17.251020 974s [302] 15.892672 15.892672 0.000000 3.382287 12.605469 12.605469 15.892672 974s [309] 6.560821 15.892672 12.605469 12.605469 17.251020 0.000000 17.251020 974s [316] 3.382287 17.251020 3.382287 12.605469 0.000000 6.560821 3.382287 974s [323] 0.000000 15.892672 17.251020 17.251020 17.251020 3.382287 6.560821 974s [330] 0.000000 0.000000 12.605469 12.605469 12.605469 0.000000 12.605469 974s [337] 0.000000 15.892672 6.560821 17.251020 12.605469 12.605469 6.560821 974s [344] 0.000000 0.000000 17.251020 0.000000 0.000000 12.605469 0.000000 974s [351] 3.382287 3.382287 6.560821 17.251020 9.671438 0.000000 9.671438 974s [358] 9.671438 12.605469 3.382287 12.605469 3.382287 17.251020 0.000000 974s [365] 12.605469 0.000000 3.382287 0.000000 3.382287 6.560821 0.000000 974s [372] 6.560821 6.560821 17.251020 15.892672 0.000000 17.251020 0.000000 974s [379] 3.382287 17.251020 3.382287 12.605469 3.382287 3.382287 12.605469 974s [386] 3.382287 3.382287 0.000000 15.892672 0.000000 12.605469 0.000000 974s [393] 15.892672 6.560821 15.892672 15.892672 6.560821 6.560821 3.382287 974s [400] 3.382287 17.251020 17.251020 6.560821 12.605469 9.671438 15.892672 974s [407] 17.251020 6.560821 3.382287 0.000000 6.560821 6.560821 15.892672 974s [414] 3.382287 0.000000 0.000000 0.000000 0.000000 3.382287 3.382287 974s [421] 0.000000 3.382287 3.382287 12.605469 17.251020 17.251020 17.251020 974s [428] 0.000000 15.892672 17.251020 17.251020 0.000000 0.000000 17.251020 974s [435] 12.605469 6.560821 0.000000 0.000000 3.382287 0.000000 15.892672 974s [442] 12.605469 17.251020 3.382287 12.605469 0.000000 17.251020 0.000000 974s [449] 6.560821 12.605469 6.560821 12.605469 15.892672 12.605469 12.605469 974s [456] 0.000000 0.000000 3.382287 0.000000 3.382287 0.000000 0.000000 974s [463] 0.000000 17.251020 6.560821 17.251020 12.605469 12.605469 3.382287 974s [470] 17.251020 0.000000 3.382287 0.000000 6.560821 0.000000 0.000000 974s [477] 3.382287 15.892672 3.382287 12.605469 0.000000 3.382287 12.605469 974s [484] 6.560821 17.251020 9.671438 15.892672 17.251020 15.892672 0.000000 974s [491] 0.000000 3.382287 3.382287 17.251020 0.000000 6.560821 12.605469 974s [498] 12.605469 12.605469 3.382287 3.382287 3.382287 15.892672 0.000000 974s [505] 6.560821 3.382287 17.251020 3.382287 12.605469 12.605469 15.892672 974s [512] 0.000000 12.605469 17.251020 6.560821 0.000000 3.382287 0.000000 974s [519] 15.892672 0.000000 12.605469 12.605469 0.000000 17.251020 0.000000 974s [526] 9.671438 0.000000 3.382287 15.892672 3.382287 3.382287 3.382287 974s [533] 17.251020 15.892672 0.000000 0.000000 0.000000 15.892672 6.560821 974s [540] 17.251020 17.251020 6.560821 0.000000 0.000000 3.382287 12.605469 974s [547] 12.605469 0.000000 3.382287 15.892672 0.000000 0.000000 3.382287 974s [554] 0.000000 0.000000 0.000000 17.251020 17.251020 17.251020 12.605469 974s [561] 0.000000 15.892672 0.000000 3.382287 3.382287 12.605469 6.560821 974s [568] 12.605469 3.382287 3.382287 0.000000 17.251020 6.560821 15.892672 974s [575] 0.000000 9.671438 3.382287 3.382287 0.000000 12.605469 3.382287 974s [582] 12.605469 3.382287 0.000000 6.560821 0.000000 3.382287 17.251020 974s [589] 3.382287 12.605469 12.605469 17.251020 3.382287 9.671438 0.000000 974s [596] 17.251020 0.000000 6.560821 9.671438 9.671438 0.000000 0.000000 974s [603] 0.000000 12.605469 17.251020 12.605469 12.605469 6.560821 6.560821 974s [610] 15.892672 3.382287 6.560821 6.560821 9.671438 17.251020 17.251020 974s [617] 0.000000 3.382287 12.605469 15.892672 3.382287 0.000000 17.251020 974s [624] 12.605469 6.560821 17.251020 17.251020 0.000000 6.560821 15.892672 974s [631] 6.560821 6.560821 0.000000 15.892672 17.251020 0.000000 3.382287 974s [638] 17.251020 974s 974s $se.fit 974s [1] 0.1322852 0.2566014 0.4930147 0.4930147 0.6747076 0.0000000 0.0000000 974s [8] 0.2566014 0.6747076 0.1322852 0.6215810 0.1322852 0.0000000 0.3782613 974s [15] 0.6215810 0.6747076 0.4930147 0.6747076 0.1322852 0.6747076 0.6747076 974s [22] 0.3782613 0.1322852 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 974s [29] 0.0000000 0.6747076 0.0000000 0.3782613 0.4930147 0.1322852 0.1322852 974s [36] 0.0000000 0.0000000 0.4930147 0.0000000 0.4930147 0.0000000 0.6215810 974s [43] 0.4930147 0.6215810 0.1322852 0.6747076 0.6747076 0.2566014 0.1322852 974s [50] 0.0000000 0.3782613 0.6747076 0.6215810 0.0000000 0.1322852 0.6747076 974s [57] 0.2566014 0.6747076 0.0000000 0.1322852 0.4930147 0.4930147 0.0000000 974s [64] 0.0000000 0.6215810 0.6215810 0.0000000 0.4930147 0.6215810 0.1322852 974s [71] 0.6215810 0.2566014 0.1322852 0.6747076 0.4930147 0.0000000 0.4930147 974s [78] 0.4930147 0.1322852 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 974s [85] 0.1322852 0.2566014 0.1322852 0.0000000 0.1322852 0.6747076 0.2566014 974s [92] 0.1322852 0.6747076 0.3782613 0.1322852 0.0000000 0.1322852 0.1322852 974s [99] 0.4930147 0.0000000 0.1322852 0.1322852 0.4930147 0.0000000 0.0000000 974s [106] 0.6747076 0.0000000 0.2566014 0.6215810 0.6747076 0.1322852 0.6747076 974s [113] 0.1322852 0.0000000 0.0000000 0.1322852 0.2566014 0.0000000 0.2566014 974s [120] 0.1322852 0.0000000 0.0000000 0.2566014 0.6215810 0.4930147 0.4930147 974s [127] 0.0000000 0.6747076 0.0000000 0.6747076 0.1322852 0.0000000 0.4930147 974s [134] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.2566014 0.2566014 974s [141] 0.1322852 0.6747076 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 974s [148] 0.6747076 0.1322852 0.6215810 0.0000000 0.6747076 0.2566014 0.1322852 974s [155] 0.4930147 0.2566014 0.2566014 0.1322852 0.1322852 0.0000000 0.1322852 974s [162] 0.0000000 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.0000000 974s [169] 0.0000000 0.1322852 0.6747076 0.1322852 0.6747076 0.6215810 0.2566014 974s [176] 0.4930147 0.1322852 0.0000000 0.4930147 0.0000000 0.4930147 0.6747076 974s [183] 0.4930147 0.0000000 0.0000000 0.4930147 0.1322852 0.4930147 0.6747076 974s [190] 0.1322852 0.1322852 0.6747076 0.1322852 0.2566014 0.1322852 0.6747076 974s [197] 0.6747076 0.0000000 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 974s [204] 0.4930147 0.4930147 0.1322852 0.1322852 0.4930147 0.6747076 0.4930147 974s [211] 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.1322852 0.1322852 974s [218] 0.0000000 0.2566014 0.0000000 0.2566014 0.2566014 0.1322852 0.0000000 974s [225] 0.1322852 0.1322852 0.6747076 0.1322852 0.0000000 0.6747076 0.1322852 974s [232] 0.2566014 0.6747076 0.0000000 0.0000000 0.1322852 0.1322852 0.4930147 974s [239] 0.2566014 0.4930147 0.1322852 0.4930147 0.6747076 0.2566014 0.6747076 974s [246] 0.6747076 0.6215810 0.0000000 0.1322852 0.1322852 0.1322852 0.0000000 974s [253] 0.4930147 0.6215810 0.2566014 0.1322852 0.1322852 0.0000000 0.0000000 974s [260] 0.4930147 0.2566014 0.1322852 0.1322852 0.4930147 0.6747076 0.0000000 974s [267] 0.2566014 0.6215810 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 974s [274] 0.6747076 0.6215810 0.2566014 0.1322852 0.4930147 0.0000000 0.1322852 974s [281] 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.6215810 0.6747076 974s [288] 0.1322852 0.6747076 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 974s [295] 0.0000000 0.6747076 0.6747076 0.4930147 0.0000000 0.4930147 0.6747076 974s [302] 0.6215810 0.6215810 0.0000000 0.1322852 0.4930147 0.4930147 0.6215810 974s [309] 0.2566014 0.6215810 0.4930147 0.4930147 0.6747076 0.0000000 0.6747076 974s [316] 0.1322852 0.6747076 0.1322852 0.4930147 0.0000000 0.2566014 0.1322852 974s [323] 0.0000000 0.6215810 0.6747076 0.6747076 0.6747076 0.1322852 0.2566014 974s [330] 0.0000000 0.0000000 0.4930147 0.4930147 0.4930147 0.0000000 0.4930147 974s [337] 0.0000000 0.6215810 0.2566014 0.6747076 0.4930147 0.4930147 0.2566014 974s [344] 0.0000000 0.0000000 0.6747076 0.0000000 0.0000000 0.4930147 0.0000000 974s [351] 0.1322852 0.1322852 0.2566014 0.6747076 0.3782613 0.0000000 0.3782613 974s [358] 0.3782613 0.4930147 0.1322852 0.4930147 0.1322852 0.6747076 0.0000000 974s [365] 0.4930147 0.0000000 0.1322852 0.0000000 0.1322852 0.2566014 0.0000000 974s [372] 0.2566014 0.2566014 0.6747076 0.6215810 0.0000000 0.6747076 0.0000000 974s [379] 0.1322852 0.6747076 0.1322852 0.4930147 0.1322852 0.1322852 0.4930147 974s [386] 0.1322852 0.1322852 0.0000000 0.6215810 0.0000000 0.4930147 0.0000000 974s [393] 0.6215810 0.2566014 0.6215810 0.6215810 0.2566014 0.2566014 0.1322852 974s [400] 0.1322852 0.6747076 0.6747076 0.2566014 0.4930147 0.3782613 0.6215810 974s [407] 0.6747076 0.2566014 0.1322852 0.0000000 0.2566014 0.2566014 0.6215810 974s [414] 0.1322852 0.0000000 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 974s [421] 0.0000000 0.1322852 0.1322852 0.4930147 0.6747076 0.6747076 0.6747076 974s [428] 0.0000000 0.6215810 0.6747076 0.6747076 0.0000000 0.0000000 0.6747076 974s [435] 0.4930147 0.2566014 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 974s [442] 0.4930147 0.6747076 0.1322852 0.4930147 0.0000000 0.6747076 0.0000000 974s [449] 0.2566014 0.4930147 0.2566014 0.4930147 0.6215810 0.4930147 0.4930147 974s [456] 0.0000000 0.0000000 0.1322852 0.0000000 0.1322852 0.0000000 0.0000000 974s [463] 0.0000000 0.6747076 0.2566014 0.6747076 0.4930147 0.4930147 0.1322852 974s [470] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.0000000 0.0000000 974s [477] 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 0.1322852 0.4930147 974s [484] 0.2566014 0.6747076 0.3782613 0.6215810 0.6747076 0.6215810 0.0000000 974s [491] 0.0000000 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.4930147 974s [498] 0.4930147 0.4930147 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 974s [505] 0.2566014 0.1322852 0.6747076 0.1322852 0.4930147 0.4930147 0.6215810 974s [512] 0.0000000 0.4930147 0.6747076 0.2566014 0.0000000 0.1322852 0.0000000 974s [519] 0.6215810 0.0000000 0.4930147 0.4930147 0.0000000 0.6747076 0.0000000 974s [526] 0.3782613 0.0000000 0.1322852 0.6215810 0.1322852 0.1322852 0.1322852 974s [533] 0.6747076 0.6215810 0.0000000 0.0000000 0.0000000 0.6215810 0.2566014 974s [540] 0.6747076 0.6747076 0.2566014 0.0000000 0.0000000 0.1322852 0.4930147 974s [547] 0.4930147 0.0000000 0.1322852 0.6215810 0.0000000 0.0000000 0.1322852 974s [554] 0.0000000 0.0000000 0.0000000 0.6747076 0.6747076 0.6747076 0.4930147 974s [561] 0.0000000 0.6215810 0.0000000 0.1322852 0.1322852 0.4930147 0.2566014 974s [568] 0.4930147 0.1322852 0.1322852 0.0000000 0.6747076 0.2566014 0.6215810 974s [575] 0.0000000 0.3782613 0.1322852 0.1322852 0.0000000 0.4930147 0.1322852 974s [582] 0.4930147 0.1322852 0.0000000 0.2566014 0.0000000 0.1322852 0.6747076 974s [589] 0.1322852 0.4930147 0.4930147 0.6747076 0.1322852 0.3782613 0.0000000 974s [596] 0.6747076 0.0000000 0.2566014 0.3782613 0.3782613 0.0000000 0.0000000 974s [603] 0.0000000 0.4930147 0.6747076 0.4930147 0.4930147 0.2566014 0.2566014 974s [610] 0.6215810 0.1322852 0.2566014 0.2566014 0.3782613 0.6747076 0.6747076 974s [617] 0.0000000 0.1322852 0.4930147 0.6215810 0.1322852 0.0000000 0.6747076 974s [624] 0.4930147 0.2566014 0.6747076 0.6747076 0.0000000 0.2566014 0.6215810 974s [631] 0.2566014 0.2566014 0.0000000 0.6215810 0.6747076 0.0000000 0.1322852 974s [638] 0.6747076 974s 974s [1] 73.61884 974s [1] 4193.584 974s [1] 4193.584 974s Dose Response Model 974s 974s Model: linear 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -19.855 -3.996 -0.064 3.775 24.956 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -11.1996 0.811196 974s delta 0.0136 0.000532 974s age -0.0126 0.009027 974s centergreen 0.0191 0.793736 974s centerred 1.1979 0.810341 974s centersilver 0.7446 0.817870 974s centeryellow 1.2027 0.826882 974s 974s Residual standard error: 6.43 974s Degrees of freedom: 631 974s 974s Call: 974s lm(formula = y ~ x + age + center, data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -24.956 -3.775 0.064 3.996 19.855 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -1.120e+01 8.112e-01 -13.806 <2e-16 *** 974s x 1.360e-02 5.316e-04 25.575 <2e-16 *** 974s age -1.255e-02 9.027e-03 -1.391 0.165 974s centergreen 1.906e-02 7.937e-01 0.024 0.981 974s centerred 1.198e+00 8.103e-01 1.478 0.140 974s centersilver 7.446e-01 8.179e-01 0.910 0.363 974s centeryellow 1.203e+00 8.269e-01 1.455 0.146 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 6.427 on 631 degrees of freedom 974s Multiple R-squared: 0.5116, Adjusted R-squared: 0.507 974s F-statistic: 110.2 on 6 and 631 DF, p-value: < 2.2e-16 974s 974s e0 delta age centergreen 974s e0 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 974s delta -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 974s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 974s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 974s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 974s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 974s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 974s centerred centersilver centeryellow 974s e0 -3.460807e-01 -3.642369e-01 -3.253015e-01 974s delta -1.885394e-06 1.847581e-05 3.596102e-06 974s age 2.140485e-04 3.347250e-04 -2.387489e-04 974s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 974s centerred 6.566532e-01 3.366063e-01 3.351988e-01 974s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 974s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 974s (Intercept) x age centergreen 974s (Intercept) 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 974s x -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 974s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 974s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 974s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 974s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 974s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 974s centerred centersilver centeryellow 974s (Intercept) -3.460807e-01 -3.642369e-01 -3.253015e-01 974s x -1.885394e-06 1.847581e-05 3.596102e-06 974s age 2.140485e-04 3.347250e-04 -2.387489e-04 974s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 974s centerred 6.566532e-01 3.366063e-01 3.351988e-01 974s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 974s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 974s $fit 974s [1] 3.385405 6.566871 12.617093 12.617093 17.266927 0.000000 0.000000 974s [8] 6.566871 17.266927 3.385405 15.907326 3.385405 0.000000 9.680356 974s [15] 15.907326 17.266927 12.617093 17.266927 3.385405 17.266927 17.266927 974s [22] 9.680356 3.385405 12.617093 0.000000 12.617093 3.385405 6.566871 974s [29] 0.000000 17.266927 0.000000 9.680356 12.617093 3.385405 3.385405 974s [36] 0.000000 0.000000 12.617093 0.000000 12.617093 0.000000 15.907326 974s [43] 12.617093 15.907326 3.385405 17.266927 17.266927 6.566871 3.385405 974s [50] 0.000000 9.680356 17.266927 15.907326 0.000000 3.385405 17.266927 974s [57] 6.566871 17.266927 0.000000 3.385405 12.617093 12.617093 0.000000 974s [64] 0.000000 15.907326 15.907326 0.000000 12.617093 15.907326 3.385405 974s [71] 15.907326 6.566871 3.385405 17.266927 12.617093 0.000000 12.617093 974s [78] 12.617093 3.385405 0.000000 0.000000 0.000000 3.385405 3.385405 974s [85] 3.385405 6.566871 3.385405 0.000000 3.385405 17.266927 6.566871 974s [92] 3.385405 17.266927 9.680356 3.385405 0.000000 3.385405 3.385405 974s [99] 12.617093 0.000000 3.385405 3.385405 12.617093 0.000000 0.000000 974s [106] 17.266927 0.000000 6.566871 15.907326 17.266927 3.385405 17.266927 974s [113] 3.385405 0.000000 0.000000 3.385405 6.566871 0.000000 6.566871 974s [120] 3.385405 0.000000 0.000000 6.566871 15.907326 12.617093 12.617093 974s [127] 0.000000 17.266927 0.000000 17.266927 3.385405 0.000000 12.617093 974s [134] 17.266927 0.000000 3.385405 0.000000 6.566871 6.566871 6.566871 974s [141] 3.385405 17.266927 0.000000 0.000000 3.385405 0.000000 15.907326 974s [148] 17.266927 3.385405 15.907326 0.000000 17.266927 6.566871 3.385405 974s [155] 12.617093 6.566871 6.566871 3.385405 3.385405 0.000000 3.385405 974s [162] 0.000000 3.385405 12.617093 3.385405 0.000000 17.266927 0.000000 974s [169] 0.000000 3.385405 17.266927 3.385405 17.266927 15.907326 6.566871 974s [176] 12.617093 3.385405 0.000000 12.617093 0.000000 12.617093 17.266927 974s [183] 12.617093 0.000000 0.000000 12.617093 3.385405 12.617093 17.266927 974s [190] 3.385405 3.385405 17.266927 3.385405 6.566871 3.385405 17.266927 974s [197] 17.266927 0.000000 12.617093 0.000000 12.617093 3.385405 6.566871 974s [204] 12.617093 12.617093 3.385405 3.385405 12.617093 17.266927 12.617093 974s [211] 3.385405 3.385405 17.266927 0.000000 6.566871 3.385405 3.385405 974s [218] 0.000000 6.566871 0.000000 6.566871 6.566871 3.385405 0.000000 974s [225] 3.385405 3.385405 17.266927 3.385405 0.000000 17.266927 3.385405 974s [232] 6.566871 17.266927 0.000000 0.000000 3.385405 3.385405 12.617093 974s [239] 6.566871 12.617093 3.385405 12.617093 17.266927 6.566871 17.266927 974s [246] 17.266927 15.907326 0.000000 3.385405 3.385405 3.385405 0.000000 974s [253] 12.617093 15.907326 6.566871 3.385405 3.385405 0.000000 0.000000 974s [260] 12.617093 6.566871 3.385405 3.385405 12.617093 17.266927 0.000000 974s [267] 6.566871 15.907326 3.385405 15.907326 3.385405 12.617093 0.000000 974s [274] 17.266927 15.907326 6.566871 3.385405 12.617093 0.000000 3.385405 974s [281] 3.385405 12.617093 3.385405 0.000000 17.266927 15.907326 17.266927 974s [288] 3.385405 17.266927 3.385405 3.385405 3.385405 15.907326 0.000000 974s [295] 0.000000 17.266927 17.266927 12.617093 0.000000 12.617093 17.266927 974s [302] 15.907326 15.907326 0.000000 3.385405 12.617093 12.617093 15.907326 974s [309] 6.566871 15.907326 12.617093 12.617093 17.266927 0.000000 17.266927 974s [316] 3.385405 17.266927 3.385405 12.617093 0.000000 6.566871 3.385405 974s [323] 0.000000 15.907326 17.266927 17.266927 17.266927 3.385405 6.566871 974s [330] 0.000000 0.000000 12.617093 12.617093 12.617093 0.000000 12.617093 974s [337] 0.000000 15.907326 6.566871 17.266927 12.617093 12.617093 6.566871 974s [344] 0.000000 0.000000 17.266927 0.000000 0.000000 12.617093 0.000000 974s [351] 3.385405 3.385405 6.566871 17.266927 9.680356 0.000000 9.680356 974s [358] 9.680356 12.617093 3.385405 12.617093 3.385405 17.266927 0.000000 974s [365] 12.617093 0.000000 3.385405 0.000000 3.385405 6.566871 0.000000 974s [372] 6.566871 6.566871 17.266927 15.907326 0.000000 17.266927 0.000000 974s [379] 3.385405 17.266927 3.385405 12.617093 3.385405 3.385405 12.617093 974s [386] 3.385405 3.385405 0.000000 15.907326 0.000000 12.617093 0.000000 974s [393] 15.907326 6.566871 15.907326 15.907326 6.566871 6.566871 3.385405 974s [400] 3.385405 17.266927 17.266927 6.566871 12.617093 9.680356 15.907326 974s [407] 17.266927 6.566871 3.385405 0.000000 6.566871 6.566871 15.907326 974s [414] 3.385405 0.000000 0.000000 0.000000 0.000000 3.385405 3.385405 974s [421] 0.000000 3.385405 3.385405 12.617093 17.266927 17.266927 17.266927 974s [428] 0.000000 15.907326 17.266927 17.266927 0.000000 0.000000 17.266927 974s [435] 12.617093 6.566871 0.000000 0.000000 3.385405 0.000000 15.907326 974s [442] 12.617093 17.266927 3.385405 12.617093 0.000000 17.266927 0.000000 974s [449] 6.566871 12.617093 6.566871 12.617093 15.907326 12.617093 12.617093 974s [456] 0.000000 0.000000 3.385405 0.000000 3.385405 0.000000 0.000000 974s [463] 0.000000 17.266927 6.566871 17.266927 12.617093 12.617093 3.385405 974s [470] 17.266927 0.000000 3.385405 0.000000 6.566871 0.000000 0.000000 974s [477] 3.385405 15.907326 3.385405 12.617093 0.000000 3.385405 12.617093 974s [484] 6.566871 17.266927 9.680356 15.907326 17.266927 15.907326 0.000000 974s [491] 0.000000 3.385405 3.385405 17.266927 0.000000 6.566871 12.617093 974s [498] 12.617093 12.617093 3.385405 3.385405 3.385405 15.907326 0.000000 974s [505] 6.566871 3.385405 17.266927 3.385405 12.617093 12.617093 15.907326 974s [512] 0.000000 12.617093 17.266927 6.566871 0.000000 3.385405 0.000000 974s [519] 15.907326 0.000000 12.617093 12.617093 0.000000 17.266927 0.000000 974s [526] 9.680356 0.000000 3.385405 15.907326 3.385405 3.385405 3.385405 974s [533] 17.266927 15.907326 0.000000 0.000000 0.000000 15.907326 6.566871 974s [540] 17.266927 17.266927 6.566871 0.000000 0.000000 3.385405 12.617093 974s [547] 12.617093 0.000000 3.385405 15.907326 0.000000 0.000000 3.385405 974s [554] 0.000000 0.000000 0.000000 17.266927 17.266927 17.266927 12.617093 974s [561] 0.000000 15.907326 0.000000 3.385405 3.385405 12.617093 6.566871 974s [568] 12.617093 3.385405 3.385405 0.000000 17.266927 6.566871 15.907326 974s [575] 0.000000 9.680356 3.385405 3.385405 0.000000 12.617093 3.385405 974s [582] 12.617093 3.385405 0.000000 6.566871 0.000000 3.385405 17.266927 974s [589] 3.385405 12.617093 12.617093 17.266927 3.385405 9.680356 0.000000 974s [596] 17.266927 0.000000 6.566871 9.680356 9.680356 0.000000 0.000000 974s [603] 0.000000 12.617093 17.266927 12.617093 12.617093 6.566871 6.566871 974s [610] 15.907326 3.385405 6.566871 6.566871 9.680356 17.266927 17.266927 974s [617] 0.000000 3.385405 12.617093 15.907326 3.385405 0.000000 17.266927 974s [624] 12.617093 6.566871 17.266927 17.266927 0.000000 6.566871 15.907326 974s [631] 6.566871 6.566871 0.000000 15.907326 17.266927 0.000000 3.385405 974s [638] 17.266927 974s 974s $se.fit 974s [1] 0.1323718 0.2567693 0.4933373 0.4933373 0.6751491 0.0000000 0.0000000 974s [8] 0.2567693 0.6751491 0.1323718 0.6219878 0.1323718 0.0000000 0.3785088 974s [15] 0.6219878 0.6751491 0.4933373 0.6751491 0.1323718 0.6751491 0.6751491 974s [22] 0.3785088 0.1323718 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 974s [29] 0.0000000 0.6751491 0.0000000 0.3785088 0.4933373 0.1323718 0.1323718 974s [36] 0.0000000 0.0000000 0.4933373 0.0000000 0.4933373 0.0000000 0.6219878 974s [43] 0.4933373 0.6219878 0.1323718 0.6751491 0.6751491 0.2567693 0.1323718 974s [50] 0.0000000 0.3785088 0.6751491 0.6219878 0.0000000 0.1323718 0.6751491 974s [57] 0.2567693 0.6751491 0.0000000 0.1323718 0.4933373 0.4933373 0.0000000 974s [64] 0.0000000 0.6219878 0.6219878 0.0000000 0.4933373 0.6219878 0.1323718 974s [71] 0.6219878 0.2567693 0.1323718 0.6751491 0.4933373 0.0000000 0.4933373 974s [78] 0.4933373 0.1323718 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 974s [85] 0.1323718 0.2567693 0.1323718 0.0000000 0.1323718 0.6751491 0.2567693 974s [92] 0.1323718 0.6751491 0.3785088 0.1323718 0.0000000 0.1323718 0.1323718 974s [99] 0.4933373 0.0000000 0.1323718 0.1323718 0.4933373 0.0000000 0.0000000 974s [106] 0.6751491 0.0000000 0.2567693 0.6219878 0.6751491 0.1323718 0.6751491 974s [113] 0.1323718 0.0000000 0.0000000 0.1323718 0.2567693 0.0000000 0.2567693 974s [120] 0.1323718 0.0000000 0.0000000 0.2567693 0.6219878 0.4933373 0.4933373 974s [127] 0.0000000 0.6751491 0.0000000 0.6751491 0.1323718 0.0000000 0.4933373 974s [134] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.2567693 0.2567693 974s [141] 0.1323718 0.6751491 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 974s [148] 0.6751491 0.1323718 0.6219878 0.0000000 0.6751491 0.2567693 0.1323718 974s [155] 0.4933373 0.2567693 0.2567693 0.1323718 0.1323718 0.0000000 0.1323718 974s [162] 0.0000000 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.0000000 974s [169] 0.0000000 0.1323718 0.6751491 0.1323718 0.6751491 0.6219878 0.2567693 974s [176] 0.4933373 0.1323718 0.0000000 0.4933373 0.0000000 0.4933373 0.6751491 974s [183] 0.4933373 0.0000000 0.0000000 0.4933373 0.1323718 0.4933373 0.6751491 974s [190] 0.1323718 0.1323718 0.6751491 0.1323718 0.2567693 0.1323718 0.6751491 974s [197] 0.6751491 0.0000000 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 974s [204] 0.4933373 0.4933373 0.1323718 0.1323718 0.4933373 0.6751491 0.4933373 974s [211] 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.1323718 0.1323718 974s [218] 0.0000000 0.2567693 0.0000000 0.2567693 0.2567693 0.1323718 0.0000000 974s [225] 0.1323718 0.1323718 0.6751491 0.1323718 0.0000000 0.6751491 0.1323718 974s [232] 0.2567693 0.6751491 0.0000000 0.0000000 0.1323718 0.1323718 0.4933373 974s [239] 0.2567693 0.4933373 0.1323718 0.4933373 0.6751491 0.2567693 0.6751491 974s [246] 0.6751491 0.6219878 0.0000000 0.1323718 0.1323718 0.1323718 0.0000000 974s [253] 0.4933373 0.6219878 0.2567693 0.1323718 0.1323718 0.0000000 0.0000000 974s [260] 0.4933373 0.2567693 0.1323718 0.1323718 0.4933373 0.6751491 0.0000000 974s [267] 0.2567693 0.6219878 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 974s [274] 0.6751491 0.6219878 0.2567693 0.1323718 0.4933373 0.0000000 0.1323718 974s [281] 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.6219878 0.6751491 974s [288] 0.1323718 0.6751491 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 974s [295] 0.0000000 0.6751491 0.6751491 0.4933373 0.0000000 0.4933373 0.6751491 974s [302] 0.6219878 0.6219878 0.0000000 0.1323718 0.4933373 0.4933373 0.6219878 974s [309] 0.2567693 0.6219878 0.4933373 0.4933373 0.6751491 0.0000000 0.6751491 974s [316] 0.1323718 0.6751491 0.1323718 0.4933373 0.0000000 0.2567693 0.1323718 974s [323] 0.0000000 0.6219878 0.6751491 0.6751491 0.6751491 0.1323718 0.2567693 974s [330] 0.0000000 0.0000000 0.4933373 0.4933373 0.4933373 0.0000000 0.4933373 974s [337] 0.0000000 0.6219878 0.2567693 0.6751491 0.4933373 0.4933373 0.2567693 974s [344] 0.0000000 0.0000000 0.6751491 0.0000000 0.0000000 0.4933373 0.0000000 974s [351] 0.1323718 0.1323718 0.2567693 0.6751491 0.3785088 0.0000000 0.3785088 974s [358] 0.3785088 0.4933373 0.1323718 0.4933373 0.1323718 0.6751491 0.0000000 974s [365] 0.4933373 0.0000000 0.1323718 0.0000000 0.1323718 0.2567693 0.0000000 974s [372] 0.2567693 0.2567693 0.6751491 0.6219878 0.0000000 0.6751491 0.0000000 974s [379] 0.1323718 0.6751491 0.1323718 0.4933373 0.1323718 0.1323718 0.4933373 974s [386] 0.1323718 0.1323718 0.0000000 0.6219878 0.0000000 0.4933373 0.0000000 974s [393] 0.6219878 0.2567693 0.6219878 0.6219878 0.2567693 0.2567693 0.1323718 974s [400] 0.1323718 0.6751491 0.6751491 0.2567693 0.4933373 0.3785088 0.6219878 974s [407] 0.6751491 0.2567693 0.1323718 0.0000000 0.2567693 0.2567693 0.6219878 974s [414] 0.1323718 0.0000000 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 974s [421] 0.0000000 0.1323718 0.1323718 0.4933373 0.6751491 0.6751491 0.6751491 974s [428] 0.0000000 0.6219878 0.6751491 0.6751491 0.0000000 0.0000000 0.6751491 974s [435] 0.4933373 0.2567693 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 974s [442] 0.4933373 0.6751491 0.1323718 0.4933373 0.0000000 0.6751491 0.0000000 974s [449] 0.2567693 0.4933373 0.2567693 0.4933373 0.6219878 0.4933373 0.4933373 974s [456] 0.0000000 0.0000000 0.1323718 0.0000000 0.1323718 0.0000000 0.0000000 974s [463] 0.0000000 0.6751491 0.2567693 0.6751491 0.4933373 0.4933373 0.1323718 974s [470] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.0000000 0.0000000 974s [477] 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 0.1323718 0.4933373 974s [484] 0.2567693 0.6751491 0.3785088 0.6219878 0.6751491 0.6219878 0.0000000 974s [491] 0.0000000 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.4933373 974s [498] 0.4933373 0.4933373 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 974s [505] 0.2567693 0.1323718 0.6751491 0.1323718 0.4933373 0.4933373 0.6219878 974s [512] 0.0000000 0.4933373 0.6751491 0.2567693 0.0000000 0.1323718 0.0000000 974s [519] 0.6219878 0.0000000 0.4933373 0.4933373 0.0000000 0.6751491 0.0000000 974s [526] 0.3785088 0.0000000 0.1323718 0.6219878 0.1323718 0.1323718 0.1323718 974s [533] 0.6751491 0.6219878 0.0000000 0.0000000 0.0000000 0.6219878 0.2567693 974s [540] 0.6751491 0.6751491 0.2567693 0.0000000 0.0000000 0.1323718 0.4933373 974s [547] 0.4933373 0.0000000 0.1323718 0.6219878 0.0000000 0.0000000 0.1323718 974s [554] 0.0000000 0.0000000 0.0000000 0.6751491 0.6751491 0.6751491 0.4933373 974s [561] 0.0000000 0.6219878 0.0000000 0.1323718 0.1323718 0.4933373 0.2567693 974s [568] 0.4933373 0.1323718 0.1323718 0.0000000 0.6751491 0.2567693 0.6219878 974s [575] 0.0000000 0.3785088 0.1323718 0.1323718 0.0000000 0.4933373 0.1323718 974s [582] 0.4933373 0.1323718 0.0000000 0.2567693 0.0000000 0.1323718 0.6751491 974s [589] 0.1323718 0.4933373 0.4933373 0.6751491 0.1323718 0.3785088 0.0000000 974s [596] 0.6751491 0.0000000 0.2567693 0.3785088 0.3785088 0.0000000 0.0000000 974s [603] 0.0000000 0.4933373 0.6751491 0.4933373 0.4933373 0.2567693 0.2567693 974s [610] 0.6219878 0.1323718 0.2567693 0.2567693 0.3785088 0.6751491 0.6751491 974s [617] 0.0000000 0.1323718 0.4933373 0.6219878 0.1323718 0.0000000 0.6751491 974s [624] 0.4933373 0.2567693 0.6751491 0.6751491 0.0000000 0.2567693 0.6219878 974s [631] 0.2567693 0.2567693 0.0000000 0.6219878 0.6751491 0.0000000 0.1323718 974s [638] 0.6751491 974s 974s $fit 974s [1] -11.57621 -11.56261 -11.54901 -10.21661 974s 974s $se.fit 974s [1] 0.6876991 0.6874618 0.6872248 0.6656515 974s 974s $fit 974s 1 2 3 4 974s -11.57621 -11.56261 -11.54901 -10.21661 974s 974s $se.fit 974s 1 2 3 4 974s 0.6876991 0.6874618 0.6872248 0.6656515 974s 974s $df 974s [1] 631 974s 974s $residual.scale 974s [1] 6.427248 974s 974s [1] 73.55102 974s [1] 2768.739 974s [1] 2768.739 974s Dose Response Model 974s 974s Model: linlog 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -18.804 -3.875 -0.163 4.453 17.258 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -13.65 2.626 974s delta 2.21 0.402 974s 974s Residual standard error: 6.12 974s Degrees of freedom: 426 974s 974s Call: 974s lm(formula = y ~ log(x + off), data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -17.2582 -4.4526 0.1627 3.8749 18.8035 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -13.6486 2.6260 -5.197 3.14e-07 *** 974s log(x + off) 2.2117 0.4016 5.508 6.29e-08 *** 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 6.116 on 426 degrees of freedom 974s Multiple R-squared: 0.06648, Adjusted R-squared: 0.06429 974s F-statistic: 30.34 on 1 and 426 DF, p-value: 6.29e-08 974s 974s e0 delta 974s e0 6.896082 -1.0477868 974s delta -1.047787 0.1612436 974s (Intercept) log(x + off) 974s (Intercept) 6.896082 -1.0477868 974s log(x + off) -1.047787 0.1612436 974s $fit 974s [1] 6.008369 5.658359 0.000000 4.514640 4.877164 4.115493 6.008369 6.641510 974s [9] 0.000000 4.115493 5.658359 6.247655 4.514640 6.247655 4.514640 4.514640 974s [17] 4.115493 0.000000 6.008369 4.877164 4.877164 6.247655 6.733679 6.247655 974s [25] 4.115493 4.877164 0.000000 6.733679 6.641510 4.514640 4.514640 5.658359 974s [33] 6.008369 4.877164 4.877164 0.000000 6.008369 6.733679 4.877164 6.008369 974s [41] 6.733679 4.877164 6.008369 6.008369 4.877164 5.658359 4.514640 4.877164 974s [49] 0.000000 4.514640 5.658359 0.000000 4.877164 6.733679 4.877164 4.514640 974s [57] 4.877164 5.658359 6.641510 4.877164 6.733679 5.658359 0.000000 6.247655 974s [65] 6.247655 5.658359 4.877164 4.877164 4.115493 4.877164 6.733679 6.247655 974s [73] 5.658359 5.658359 4.877164 5.535104 6.008369 5.535104 6.247655 6.008369 974s [81] 6.247655 6.008369 5.535104 4.115493 5.658359 4.877164 6.008369 4.877164 974s [89] 6.247655 0.000000 6.008369 4.514640 4.514640 6.008369 4.877164 5.658359 974s [97] 4.877164 6.008369 6.733679 5.658359 4.115493 6.247655 0.000000 6.008369 974s [105] 6.247655 4.877164 6.733679 5.658359 4.115493 5.658359 5.658359 5.658359 974s [113] 6.008369 6.008369 6.733679 4.115493 4.877164 4.115493 4.877164 5.658359 974s [121] 4.514640 6.247655 4.877164 6.641510 4.115493 4.877164 5.658359 4.877164 974s [129] 4.514640 0.000000 6.008369 4.514640 6.733679 4.877164 4.514640 4.877164 974s [137] 5.658359 5.658359 4.115493 6.247655 6.641510 4.877164 5.658359 4.514640 974s [145] 4.115493 4.115493 6.733679 4.877164 0.000000 4.877164 5.658359 4.514640 974s [153] 6.641510 4.514640 4.877164 4.115493 6.247655 4.115493 6.008369 4.877164 974s [161] 4.514640 4.115493 4.877164 6.733679 6.247655 4.514640 4.877164 5.658359 974s [169] 4.115493 0.000000 5.658359 5.658359 4.877164 4.514640 4.115493 4.877164 974s [177] 0.000000 5.658359 6.247655 6.733679 0.000000 6.008369 4.514640 4.877164 974s [185] 0.000000 6.733679 5.658359 6.247655 4.514640 5.535104 5.658359 4.877164 974s [193] 5.658359 6.733679 6.641510 4.514640 6.008369 4.115493 4.877164 4.877164 974s [201] 4.115493 6.247655 5.658359 6.247655 5.535104 0.000000 4.115493 6.641510 974s [209] 6.247655 6.008369 4.115493 4.514640 4.514640 6.641510 6.733679 6.733679 974s [217] 5.658359 5.658359 6.008369 4.115493 5.658359 6.641510 6.641510 4.877164 974s [225] 0.000000 4.877164 0.000000 4.115493 4.877164 5.535104 4.115493 5.658359 974s [233] 6.733679 4.514640 6.733679 4.514640 4.514640 5.658359 6.008369 5.658359 974s [241] 4.877164 4.514640 4.115493 4.115493 4.115493 6.247655 5.658359 0.000000 974s [249] 4.115493 4.514640 6.247655 6.733679 6.008369 4.877164 4.115493 4.514640 974s [257] 0.000000 0.000000 5.658359 5.658359 4.514640 5.658359 4.514640 4.115493 974s [265] 4.877164 4.877164 4.514640 5.658359 6.008369 4.514640 4.115493 0.000000 974s [273] 4.877164 4.877164 4.115493 6.008369 4.514640 6.008369 4.514640 4.877164 974s [281] 6.008369 0.000000 0.000000 5.658359 6.247655 6.008369 6.008369 6.247655 974s [289] 4.877164 4.877164 4.514640 6.008369 6.008369 4.115493 6.641510 6.733679 974s [297] 4.514640 4.877164 4.877164 4.877164 6.008369 6.641510 4.877164 5.658359 974s [305] 4.514640 5.535104 4.877164 6.008369 6.008369 5.658359 4.514640 6.008369 974s [313] 6.247655 5.658359 6.733679 6.008369 6.247655 5.658359 5.535104 4.877164 974s [321] 5.658359 4.877164 4.877164 5.658359 5.658359 4.877164 4.115493 4.877164 974s [329] 5.658359 4.877164 4.877164 4.877164 5.658359 6.733679 6.008369 6.247655 974s [337] 4.877164 5.535104 6.008369 4.115493 6.008369 6.247655 4.115493 6.008369 974s [345] 5.658359 4.877164 6.247655 6.641510 5.658359 4.115493 6.733679 6.008369 974s [353] 5.658359 4.115493 4.514640 4.877164 6.733679 5.658359 0.000000 6.641510 974s [361] 6.733679 4.115493 6.247655 4.877164 4.877164 5.658359 4.514640 4.115493 974s [369] 4.877164 4.877164 4.877164 5.658359 4.877164 0.000000 5.658359 4.877164 974s [377] 4.877164 4.514640 4.514640 6.733679 6.008369 6.733679 4.514640 4.514640 974s [385] 4.115493 5.535104 4.877164 4.877164 6.247655 5.658359 6.733679 4.514640 974s [393] 4.877164 5.658359 6.733679 6.733679 4.514640 6.008369 5.658359 6.733679 974s [401] 6.733679 6.733679 0.000000 6.641510 6.733679 4.115493 4.877164 6.247655 974s [409] 0.000000 4.115493 4.514640 4.877164 4.877164 4.514640 6.733679 6.247655 974s [417] 5.658359 4.877164 4.877164 0.000000 4.877164 4.877164 0.000000 6.008369 974s [425] 4.115493 4.514640 4.877164 0.000000 974s 974s $se.fit 974s [1] 1.0908488 1.0273028 0.0000000 0.8196550 0.8854731 0.7471878 1.0908488 974s [8] 1.2057987 0.0000000 0.7471878 1.0273028 1.1342924 0.8196550 1.1342924 974s [15] 0.8196550 0.8196550 0.7471878 0.0000000 1.0908488 0.8854731 0.8854731 974s [22] 1.1342924 1.2225325 1.1342924 0.7471878 0.8854731 0.0000000 1.2225325 974s [29] 1.2057987 0.8196550 0.8196550 1.0273028 1.0908488 0.8854731 0.8854731 974s [36] 0.0000000 1.0908488 1.2225325 0.8854731 1.0908488 1.2225325 0.8854731 974s [43] 1.0908488 1.0908488 0.8854731 1.0273028 0.8196550 0.8854731 0.0000000 974s [50] 0.8196550 1.0273028 0.0000000 0.8854731 1.2225325 0.8854731 0.8196550 974s [57] 0.8854731 1.0273028 1.2057987 0.8854731 1.2225325 1.0273028 0.0000000 974s [64] 1.1342924 1.1342924 1.0273028 0.8854731 0.8854731 0.7471878 0.8854731 974s [71] 1.2225325 1.1342924 1.0273028 1.0273028 0.8854731 1.0049252 1.0908488 974s [78] 1.0049252 1.1342924 1.0908488 1.1342924 1.0908488 1.0049252 0.7471878 974s [85] 1.0273028 0.8854731 1.0908488 0.8854731 1.1342924 0.0000000 1.0908488 974s [92] 0.8196550 0.8196550 1.0908488 0.8854731 1.0273028 0.8854731 1.0908488 974s [99] 1.2225325 1.0273028 0.7471878 1.1342924 0.0000000 1.0908488 1.1342924 974s [106] 0.8854731 1.2225325 1.0273028 0.7471878 1.0273028 1.0273028 1.0273028 974s [113] 1.0908488 1.0908488 1.2225325 0.7471878 0.8854731 0.7471878 0.8854731 974s [120] 1.0273028 0.8196550 1.1342924 0.8854731 1.2057987 0.7471878 0.8854731 974s [127] 1.0273028 0.8854731 0.8196550 0.0000000 1.0908488 0.8196550 1.2225325 974s [134] 0.8854731 0.8196550 0.8854731 1.0273028 1.0273028 0.7471878 1.1342924 974s [141] 1.2057987 0.8854731 1.0273028 0.8196550 0.7471878 0.7471878 1.2225325 974s [148] 0.8854731 0.0000000 0.8854731 1.0273028 0.8196550 1.2057987 0.8196550 974s [155] 0.8854731 0.7471878 1.1342924 0.7471878 1.0908488 0.8854731 0.8196550 974s [162] 0.7471878 0.8854731 1.2225325 1.1342924 0.8196550 0.8854731 1.0273028 974s [169] 0.7471878 0.0000000 1.0273028 1.0273028 0.8854731 0.8196550 0.7471878 974s [176] 0.8854731 0.0000000 1.0273028 1.1342924 1.2225325 0.0000000 1.0908488 974s [183] 0.8196550 0.8854731 0.0000000 1.2225325 1.0273028 1.1342924 0.8196550 974s [190] 1.0049252 1.0273028 0.8854731 1.0273028 1.2225325 1.2057987 0.8196550 974s [197] 1.0908488 0.7471878 0.8854731 0.8854731 0.7471878 1.1342924 1.0273028 974s [204] 1.1342924 1.0049252 0.0000000 0.7471878 1.2057987 1.1342924 1.0908488 974s [211] 0.7471878 0.8196550 0.8196550 1.2057987 1.2225325 1.2225325 1.0273028 974s [218] 1.0273028 1.0908488 0.7471878 1.0273028 1.2057987 1.2057987 0.8854731 974s [225] 0.0000000 0.8854731 0.0000000 0.7471878 0.8854731 1.0049252 0.7471878 974s [232] 1.0273028 1.2225325 0.8196550 1.2225325 0.8196550 0.8196550 1.0273028 974s [239] 1.0908488 1.0273028 0.8854731 0.8196550 0.7471878 0.7471878 0.7471878 974s [246] 1.1342924 1.0273028 0.0000000 0.7471878 0.8196550 1.1342924 1.2225325 974s [253] 1.0908488 0.8854731 0.7471878 0.8196550 0.0000000 0.0000000 1.0273028 974s [260] 1.0273028 0.8196550 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 974s [267] 0.8196550 1.0273028 1.0908488 0.8196550 0.7471878 0.0000000 0.8854731 974s [274] 0.8854731 0.7471878 1.0908488 0.8196550 1.0908488 0.8196550 0.8854731 974s [281] 1.0908488 0.0000000 0.0000000 1.0273028 1.1342924 1.0908488 1.0908488 974s [288] 1.1342924 0.8854731 0.8854731 0.8196550 1.0908488 1.0908488 0.7471878 974s [295] 1.2057987 1.2225325 0.8196550 0.8854731 0.8854731 0.8854731 1.0908488 974s [302] 1.2057987 0.8854731 1.0273028 0.8196550 1.0049252 0.8854731 1.0908488 974s [309] 1.0908488 1.0273028 0.8196550 1.0908488 1.1342924 1.0273028 1.2225325 974s [316] 1.0908488 1.1342924 1.0273028 1.0049252 0.8854731 1.0273028 0.8854731 974s [323] 0.8854731 1.0273028 1.0273028 0.8854731 0.7471878 0.8854731 1.0273028 974s [330] 0.8854731 0.8854731 0.8854731 1.0273028 1.2225325 1.0908488 1.1342924 974s [337] 0.8854731 1.0049252 1.0908488 0.7471878 1.0908488 1.1342924 0.7471878 974s [344] 1.0908488 1.0273028 0.8854731 1.1342924 1.2057987 1.0273028 0.7471878 974s [351] 1.2225325 1.0908488 1.0273028 0.7471878 0.8196550 0.8854731 1.2225325 974s [358] 1.0273028 0.0000000 1.2057987 1.2225325 0.7471878 1.1342924 0.8854731 974s [365] 0.8854731 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 0.8854731 974s [372] 1.0273028 0.8854731 0.0000000 1.0273028 0.8854731 0.8854731 0.8196550 974s [379] 0.8196550 1.2225325 1.0908488 1.2225325 0.8196550 0.8196550 0.7471878 974s [386] 1.0049252 0.8854731 0.8854731 1.1342924 1.0273028 1.2225325 0.8196550 974s [393] 0.8854731 1.0273028 1.2225325 1.2225325 0.8196550 1.0908488 1.0273028 974s [400] 1.2225325 1.2225325 1.2225325 0.0000000 1.2057987 1.2225325 0.7471878 974s [407] 0.8854731 1.1342924 0.0000000 0.7471878 0.8196550 0.8854731 0.8854731 974s [414] 0.8196550 1.2225325 1.1342924 1.0273028 0.8854731 0.8854731 0.0000000 974s [421] 0.8854731 0.8854731 0.0000000 1.0908488 0.7471878 0.8196550 0.8854731 974s [428] 0.0000000 974s 974s [1] 40.01633 974s [1] 2773.961 974s [1] 2773.961 974s Dose Response Model 974s 974s Model: linlog 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -17.993 -3.920 -0.142 4.548 17.772 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -12.53812 2.7627 974s delta 2.19176 0.4045 974s age -0.00815 0.0103 974s centergreen -0.11764 0.9231 974s centerred -1.68381 0.9385 974s centersilver -0.40779 0.9137 974s centeryellow -0.83235 0.9332 974s 974s Residual standard error: 6.12 974s Degrees of freedom: 421 974s 974s Call: 974s lm(formula = y ~ log(x + off) + age + center, data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -17.7720 -4.5476 0.1417 3.9205 17.9926 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -12.538125 2.762741 -4.538 7.41e-06 *** 974s log(x + off) 2.191761 0.404501 5.418 1.01e-07 *** 974s age -0.008153 0.010337 -0.789 0.4308 974s centergreen -0.117636 0.923131 -0.127 0.8987 974s centerred -1.683810 0.938487 -1.794 0.0735 . 974s centersilver -0.407788 0.913735 -0.446 0.6556 974s centeryellow -0.832351 0.933224 -0.892 0.3730 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 6.118 on 421 degrees of freedom 974s Multiple R-squared: 0.07685, Adjusted R-squared: 0.06369 974s F-statistic: 5.841 on 6 and 421 DF, p-value: 7.284e-06 974s 974s e0 delta age centergreen 974s e0 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 974s delta -1.065954459 0.1636213662 0.0003614495 -0.0285500750 974s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 974s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 974s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 974s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 974s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 974s centerred centersilver centeryellow 974s e0 -0.3271697994 -0.3433662837 -0.3049047728 974s delta -0.0143714026 -0.0139200933 -0.0188552161 974s age 0.0001539174 0.0004143178 0.0002799329 974s centergreen 0.4142785346 0.4148464502 0.4153997441 974s centerred 0.8807582409 0.4133097826 0.4135270947 974s centersilver 0.4133097826 0.8349108233 0.4142615949 974s centeryellow 0.4135270947 0.4142615949 0.8709075166 974s (Intercept) log(x + off) age centergreen 974s (Intercept) 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 974s log(x + off) -1.065954459 0.1636213662 0.0003614495 -0.0285500750 974s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 974s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 974s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 974s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 974s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 974s centerred centersilver centeryellow 974s (Intercept) -0.3271697994 -0.3433662837 -0.3049047728 974s log(x + off) -0.0143714026 -0.0139200933 -0.0188552161 974s age 0.0001539174 0.0004143178 0.0002799329 974s centergreen 0.4142785346 0.4148464502 0.4153997441 974s centerred 0.8807582409 0.4133097826 0.4135270947 974s centersilver 0.4133097826 0.8349108233 0.4142615949 974s centeryellow 0.4135270947 0.4142615949 0.8709075166 974s $fit 974s [1] -3.511779 -3.480690 -3.450035 -1.567022 974s 974s $se.fit 974s [1] 1.1058048 1.1012159 1.0967017 0.8461873 974s 974s $fit 974s 1 2 3 4 974s -3.511779 -3.480690 -3.450035 -1.567022 974s 974s $se.fit 974s 1 2 3 4 974s 1.1058048 1.1012159 1.0967017 0.8461873 974s 974s $df 974s [1] 421 974s 974s $residual.scale 974s [1] 6.117927 974s 974s [1] 40.47058 974s [1] 54.33574 974s [1] 54.33574 974s Dose Response Model 974s 974s Model: quadratic 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -9.08e-01 -3.06e-01 3.08e-05 2.39e-01 7.57e-01 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -3.12e+00 9.19e-02 974s b1 -6.61e-04 1.47e-03 974s b2 5.18e-06 4.40e-06 974s 974s Residual standard error: 0.401 974s Degrees of freedom: 46 974s 974s Call: 974s lm(formula = y ~ x + I(x^2), data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -0.75741 -0.23947 -0.00003 0.30638 0.90831 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -3.118e+00 9.195e-02 -33.914 <2e-16 *** 974s x -6.612e-04 1.466e-03 -0.451 0.654 974s I(x^2) 5.175e-06 4.401e-06 1.176 0.246 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.4007 on 46 degrees of freedom 974s Multiple R-squared: 0.1193, Adjusted R-squared: 0.08097 974s F-statistic: 3.115 on 2 and 46 DF, p-value: 0.05388 974s 974s e0 b1 b2 974s e0 8.454726e-03 -7.868733e-05 1.608713e-07 974s b1 -7.868733e-05 2.149290e-06 -6.145868e-09 974s b2 1.608713e-07 -6.145868e-09 1.936461e-11 974s (Intercept) x I(x^2) 974s (Intercept) 8.454726e-03 -7.868733e-05 1.608713e-07 974s x -7.868733e-05 2.149290e-06 -6.145868e-09 974s I(x^2) 1.608713e-07 -6.145868e-09 1.936461e-11 974s $fit 974s [1] 0.49280484 0.00000000 0.05861756 0.00000000 0.25773527 0.00000000 974s [7] 0.05861756 0.00000000 0.25773527 0.05861756 0.25773527 -0.01991690 974s [13] 0.05861756 -0.01991690 0.05861756 0.02376374 0.05861756 0.05861756 974s [19] 0.02376374 0.49280484 0.00000000 0.49280484 0.00000000 0.05861756 974s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.02376374 974s [31] 0.25773527 0.00000000 0.25773527 -0.01991690 0.25773527 0.00000000 974s [37] 0.00000000 0.00000000 0.25773527 0.00000000 0.25773527 -0.01991690 974s [43] 0.25773527 0.02376374 0.05861756 -0.01991690 0.00000000 0.25773527 974s [49] 0.00000000 974s 974s $se.fit 974s [1] 0.19776187 0.00000000 0.13594191 0.00000000 0.13486241 0.00000000 974s [7] 0.13594191 0.00000000 0.13486241 0.13594191 0.13486241 0.09012454 974s [13] 0.13594191 0.09012454 0.13594191 0.13105561 0.13594191 0.13594191 974s [19] 0.13105561 0.19776187 0.00000000 0.19776187 0.00000000 0.13594191 974s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.13105561 974s [31] 0.13486241 0.00000000 0.13486241 0.09012454 0.13486241 0.00000000 974s [37] 0.00000000 0.00000000 0.13486241 0.00000000 0.13486241 0.09012454 974s [43] 0.13486241 0.13105561 0.13594191 0.09012454 0.00000000 0.13486241 974s [49] 0.00000000 974s 974s $fit 974s [1] -3.118383 -3.124477 -3.132746 974s 974s $se.fit 974s [1] 0.09194958 0.08435629 0.08409705 974s 974s $fit 974s 1 2 3 974s -3.118383 -3.124477 -3.132746 974s 974s $se.fit 974s 1 2 3 974s 0.09194958 0.08435629 0.08409705 974s 974s $df 974s [1] 46 974s 974s $residual.scale 974s [1] 0.4007027 974s 974s [1] 508.0679 974s [1] 62.95473 974s [1] 62.95473 974s Dose Response Model 974s 974s Model: quadratic 974s Fit-type: normal 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -0.87232 -0.24673 -0.00516 0.29930 0.65583 974s 974s Coefficients with approx. stand. error: 974s Estimate Std. Error 974s e0 -3.08e+00 1.69e-01 974s b1 -5.76e-04 1.59e-03 974s b2 4.82e-06 4.74e-06 974s age -1.60e-03 2.09e-03 974s centergreen -4.89e-03 2.03e-01 974s centerred 6.72e-02 1.75e-01 974s centersilver 7.81e-02 1.87e-01 974s centeryellow 9.70e-02 1.95e-01 974s 974s Residual standard error: 0.418 974s Degrees of freedom: 41 974s 974s Call: 974s lm(formula = y ~ x + I(x^2) + age + center, data = datset) 974s 974s Residuals: 974s Min 1Q Median 3Q Max 974s -0.65583 -0.29930 0.00516 0.24673 0.87232 974s 974s Coefficients: 974s Estimate Std. Error t value Pr(>|t|) 974s (Intercept) -3.076e+00 1.692e-01 -18.182 <2e-16 *** 974s x -5.756e-04 1.594e-03 -0.361 0.720 974s I(x^2) 4.822e-06 4.738e-06 1.018 0.315 974s age -1.604e-03 2.092e-03 -0.767 0.448 974s centergreen -4.891e-03 2.034e-01 -0.024 0.981 974s centerred 6.715e-02 1.753e-01 0.383 0.704 974s centersilver 7.814e-02 1.875e-01 0.417 0.679 974s centeryellow 9.700e-02 1.950e-01 0.497 0.622 974s --- 974s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 974s 974s Residual standard error: 0.4185 on 41 degrees of freedom 974s Multiple R-squared: 0.1437, Adjusted R-squared: -0.002451 974s F-statistic: 0.9832 on 7 and 41 DF, p-value: 0.4566 974s 974s e0 b1 b2 age 974s e0 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 974s b1 -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 974s b2 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 974s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 974s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 974s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 974s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 974s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 974s centergreen centerred centersilver centeryellow 974s e0 -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 974s b1 -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 974s b2 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 974s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 974s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 974s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 974s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 974s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 974s (Intercept) x I(x^2) age 974s (Intercept) 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 974s x -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 974s I(x^2) 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 974s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 974s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 974s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 974s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 974s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 974s centergreen centerred centersilver centeryellow 974s (Intercept) -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 974s x -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 974s I(x^2) 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 974s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 974s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 974s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 974s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 974s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 974s $fit 974s [1] -3.124527 -3.129801 -3.133870 974s 974s $se.fit 974s [1] 0.1418548 0.1377349 0.1475950 974s 974s $fit 974s 1 2 3 974s -3.124527 -3.129801 -3.133870 974s 974s $se.fit 974s 1 2 3 974s 0.1418548 0.1377349 0.1475950 974s 974s $df 974s [1] 41 974s 974s $residual.scale 974s [1] 0.418494 974s 974s [1] 215.5724 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974s Warning message: 974s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 974s mns is not a numeric but a array, converting with as.numeric() 974s [1] 0 0 0 0 0 974s [1] 0 0 0 0 0 974s Warning message: 974s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 974s mns is not a numeric but a array, converting with as.numeric() 974s Warning message: 974s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 974s mns is not a numeric but a array, converting with as.numeric() 974s e0 delta 974s 0.47569910 0.02447331 974s e0 delta 974s 0.47569910 0.02447331 974s Warning message: 974s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 974s mns is not a numeric but a array, converting with as.numeric() 974s testsFitting.R passed 974s Loading required package: DoseFinding 975s testsMCPMod.R passed 975s Loading required package: DoseFinding 976s Loading required package: multcomp 976s Loading required package: mvtnorm 976s Loading required package: survival 976s Loading required package: TH.data 976s Loading required package: MASS 976s 976s Attaching package: ‘TH.data’ 976s 976s The following object is masked from ‘package:MASS’: 976s 976s geyser 976s 976s 976s Simultaneous Tests for General Linear Hypotheses 976s 976s Multiple Comparisons of Means: User-defined Contrasts 976s 976s 976s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 976s 976s Linear Hypotheses: 976s Estimate Std. Error t value Pr(>t) 976s linear <= 0 0.07260 0.05755 1.262 0.1756 976s betaMod <= 0 0.12179 0.05559 2.191 0.0287 * 976s sigEmax <= 0 0.08677 0.05648 1.536 0.1114 976s --- 976s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 976s (Adjusted p values reported -- single-step method) 976s 976s Multiple Contrast Test 976s 976s Contrasts: 976s linear betaMod sigEmax 976s 0 -0.472 -0.492 -0.349 976s 172 -0.391 -0.345 -0.489 976s 285 -0.132 0.032 -0.240 976s 516 0.262 0.799 0.503 976s 761 0.733 0.007 0.574 976s 976s Contrast Correlation: 976s linear betaMod sigEmax 976s linear 1.000 0.645 0.942 976s betaMod 0.645 1.000 0.741 976s sigEmax 0.942 0.741 1.000 976s 976s Multiple Contrast Test: 976s t-Stat adj-p 976s betaMod 2.191 0.0287 976s sigEmax 1.536 0.1112 976s linear 1.262 0.1757 976s 976s Simultaneous Tests for General Linear Hypotheses 976s 976s Multiple Comparisons of Means: User-defined Contrasts 976s 976s 976s Fit: lm(formula = y ~ x, data = dd2) 976s 976s Linear Hypotheses: 976s Estimate Std. Error t value Pr(>t) 976s linear <= 0 0.07985 0.05691 1.403 0.1404 976s betaMod <= 0 0.11839 0.05507 2.150 0.0314 * 976s sigEmax <= 0 0.09407 0.05594 1.682 0.0853 . 976s --- 976s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 976s (Adjusted p values reported -- single-step method) 976s 976s Multiple Contrast Test 976s 976s Contrasts: 976s linear betaMod sigEmax 976s 0 -0.472 -0.487 -0.347 976s 172 -0.389 -0.348 -0.490 976s 285 -0.132 0.030 -0.239 976s 516 0.255 0.800 0.500 976s 761 0.738 0.005 0.576 976s 976s Contrast Correlation: 976s linear betaMod sigEmax 976s linear 1.000 0.642 0.941 976s betaMod 0.642 1.000 0.740 976s sigEmax 0.941 0.740 1.000 976s 976s Multiple Contrast Test: 976s t-Stat adj-p 976s betaMod 2.150 0.0317 976s sigEmax 1.682 0.0852 976s linear 1.403 0.1403 976s 976s Simultaneous Tests for General Linear Hypotheses 976s 976s Multiple Comparisons of Means: User-defined Contrasts 976s 976s 976s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 976s 976s Linear Hypotheses: 976s Estimate Std. Error t value Pr(>t) 976s linlog <= 0 0.09114 0.05971 1.526 0.1510 976s logistic1 <= 0 0.10293 0.05761 1.787 0.0940 . 976s logistic2 <= 0 0.09583 0.05707 1.679 0.1154 976s exponential <= 0 0.02544 0.05514 0.461 0.5623 976s quadratic <= 0 0.11676 0.05980 1.952 0.0674 . 976s --- 976s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 976s (Adjusted p values reported -- single-step method) 976s 976s Multiple Contrast Test 976s 976s Contrasts: 976s linlog logistic1 logistic2 exponential quadratic 976s 0 -0.624 -0.448 -0.457 -0.268 -0.665 976s 172 -0.309 -0.590 -0.475 -0.347 -0.055 976s 285 -0.049 0.101 -0.118 -0.191 0.199 976s 516 0.366 0.500 0.499 -0.069 0.696 976s 761 0.616 0.437 0.550 0.875 -0.174 976s 976s Contrast Correlation: 976s linlog logistic1 logistic2 exponential quadratic 976s linlog 1.000 0.902 0.955 0.799 0.651 976s logistic1 0.902 1.000 0.949 0.671 0.660 976s logistic2 0.955 0.949 1.000 0.792 0.586 976s exponential 0.799 0.671 0.792 1.000 0.063 976s quadratic 0.651 0.660 0.586 0.063 1.000 976s 976s Multiple Contrast Test: 976s t-Stat adj-p 976s quadratic 1.952 0.0675 976s logistic1 1.787 0.0941 976s logistic2 1.679 0.1154 976s linlog 1.526 0.1506 976s exponential 0.461 0.5625 976s 976s Simultaneous Tests for General Linear Hypotheses 976s 976s Multiple Comparisons of Means: User-defined Contrasts 976s 976s 976s Fit: lm(formula = y ~ x, data = dd2) 976s 976s Linear Hypotheses: 976s Estimate Std. Error t value Pr(>t) 976s linlog <= 0 0.09484 0.05913 1.604 0.1320 976s logistic1 <= 0 0.10608 0.05706 1.859 0.0817 . 976s logistic2 <= 0 0.10119 0.05654 1.790 0.0928 . 976s exponential <= 0 0.03666 0.05440 0.674 0.4665 976s quadratic <= 0 0.10792 0.05938 1.817 0.0885 . 976s --- 976s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 976s (Adjusted p values reported -- single-step method) 976s 976s Multiple Contrast Test 976s 976s Contrasts: 976s linlog logistic1 logistic2 exponential quadratic 976s 0 -0.623 -0.445 -0.455 -0.270 -0.664 976s 172 -0.307 -0.592 -0.476 -0.342 -0.056 976s 285 -0.050 0.101 -0.118 -0.189 0.197 976s 516 0.358 0.497 0.496 -0.076 0.698 976s 761 0.622 0.440 0.554 0.877 -0.175 976s 976s Contrast Correlation: 976s linlog logistic1 logistic2 exponential quadratic 976s linlog 1.000 0.901 0.955 0.800 0.648 976s logistic1 0.901 1.000 0.949 0.670 0.658 976s logistic2 0.955 0.949 1.000 0.792 0.584 976s exponential 0.800 0.670 0.792 1.000 0.062 976s quadratic 0.648 0.658 0.584 0.062 1.000 976s 976s Multiple Contrast Test: 976s t-Stat adj-p 976s logistic1 1.859 0.0816 976s quadratic 1.817 0.0887 976s logistic2 1.790 0.0933 976s linlog 1.604 0.1316 976s exponential 0.674 0.4667 977s 977s Simultaneous Tests for General Linear Hypotheses 977s 977s Multiple Comparisons of Means: User-defined Contrasts 977s 977s 977s Fit: lm(formula = y ~ x, data = dd2) 977s 977s Linear Hypotheses: 977s Estimate Std. Error t value Pr(>t) 977s linlog <= 0 -0.2995 1.0212 -0.293 0.821 977s logistic1 <= 0 -0.1795 0.9837 -0.182 0.785 977s logistic2 <= 0 -0.1401 0.9877 -0.142 0.771 977s exponential <= 0 -0.2892 0.9568 -0.302 0.823 977s quadratic <= 0 -0.1973 1.2830 -0.154 0.776 977s (Adjusted p values reported -- single-step method) 977s 977s Multiple Contrast Test 977s 977s Contrasts: 977s linlog logistic1 logistic2 exponential quadratic 977s 0 -0.464 -0.268 -0.289 -0.207 -0.751 977s 124 -0.436 -0.627 -0.556 -0.450 -0.241 977s 272 0.013 -0.006 -0.083 -0.187 0.476 977s 560 0.127 0.196 0.172 -0.004 0.353 977s 865 0.761 0.705 0.755 0.848 0.164 977s 977s Contrast Correlation: 977s linlog logistic1 logistic2 exponential quadratic 977s linlog 1.000 0.950 0.963 0.890 0.665 977s logistic1 0.950 1.000 0.992 0.879 0.591 977s logistic2 0.963 0.992 1.000 0.922 0.542 977s exponential 0.890 0.879 0.922 1.000 0.252 977s quadratic 0.665 0.591 0.542 0.252 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s logistic2 -0.142 0.771 977s quadratic -0.154 0.776 977s logistic1 -0.182 0.785 977s linlog -0.293 0.821 977s exponential -0.302 0.823 977s 977s Simultaneous Tests for General Linear Hypotheses 977s 977s Multiple Comparisons of Means: User-defined Contrasts 977s 977s 977s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 977s 977s Linear Hypotheses: 977s Estimate Std. Error z value Pr(>z) 977s linear <= 0 0.19645 0.33561 0.585 0.395 977s betaMod <= 0 0.03813 0.31565 0.121 0.587 977s sigEmax <= 0 0.30472 0.34592 0.881 0.283 977s (Adjusted p values reported -- single-step method) 977s 977s Multiple Contrast Test 977s 977s Contrasts: 977s linear betaMod sigEmax 977s 0 -0.794 -0.793 -0.774 977s 190 -0.064 -0.022 -0.192 977s 344 0.197 0.577 0.317 977s 404 0.098 0.190 0.163 977s 616 0.563 0.048 0.487 977s 977s Contrast Correlation: 977s linear betaMod sigEmax 977s linear 1.000 0.723 0.962 977s betaMod 0.723 1.000 0.793 977s sigEmax 0.962 0.793 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s sigEmax 0.881 0.283 977s linear 0.585 0.395 977s betaMod 0.121 0.587 977s 977s Simultaneous Tests for General Linear Hypotheses 977s 977s Multiple Comparisons of Means: User-defined Contrasts 977s 977s 977s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 977s 977s Linear Hypotheses: 977s Estimate Std. Error z value Pr(>z) 977s linear <= 0 0.2547 0.1877 1.357 0.1500 977s betaMod <= 0 0.2367 0.2371 0.999 0.2555 977s sigEmax <= 0 0.3698 0.1889 1.958 0.0476 * 977s --- 977s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 977s (Adjusted p values reported -- single-step method) 977s 977s Multiple Contrast Test 977s 977s Contrasts: 977s linear betaMod sigEmax 977s 0 0.418 0.634 0.310 977s 68.5 0.114 0.150 0.139 977s 85.9 0.387 0.362 0.551 977s 166 0.027 -0.572 -0.033 977s 197 -0.015 -0.158 -0.054 977s 278 -0.129 -0.264 -0.172 977s 332 -0.803 -0.152 -0.740 977s 977s Contrast Correlation: 977s linear betaMod sigEmax 977s linear 1.000 0.635 0.967 977s betaMod 0.635 1.000 0.677 977s sigEmax 0.967 0.677 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s sigEmax 1.958 0.0477 977s linear 1.357 0.1501 977s betaMod 0.999 0.2556 977s 977s Simultaneous Tests for General Linear Hypotheses 977s 977s Multiple Comparisons of Means: User-defined Contrasts 977s 977s 977s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 977s 977s Linear Hypotheses: 977s Estimate Std. Error z value Pr(>z) 977s linear <= 0 0.3391 0.3218 1.054 0.226 977s betaMod <= 0 0.3556 0.3124 1.138 0.201 977s sigEmax <= 0 0.2935 0.3497 0.839 0.299 977s (Adjusted p values reported -- single-step method) 977s 977s Multiple Contrast Test 977s 977s Contrasts: 977s linear betaMod sigEmax 977s 0 -0.721 -0.796 -0.547 977s 79.1 -0.129 -0.102 -0.312 977s 117 0.005 0.106 -0.137 977s 208 0.191 0.519 0.288 977s 398 0.654 0.274 0.708 977s 977s Contrast Correlation: 977s linear betaMod sigEmax 977s linear 1.000 0.785 0.954 977s betaMod 0.785 1.000 0.742 977s sigEmax 0.954 0.742 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s betaMod 1.138 0.201 977s linear 1.054 0.226 977s sigEmax 0.839 0.299 977s Warning message: 977s In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 977s Warning from mvtnorm::pmvt: univariate: using pnorm. 977s 977s Simultaneous Tests for General Linear Hypotheses 977s 977s Multiple Comparisons of Means: User-defined Contrasts 977s 977s 977s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 977s 977s Linear Hypotheses: 977s Estimate Std. Error z value Pr(>z) 977s linear <= 0 0.3391 0.3218 1.054 0.146 977s (Adjusted p values reported -- single-step method) 977s 977s Multiple Contrast Test 977s 977s Contrasts: 977s linear 977s 0 -0.721 977s 79.1 -0.129 977s 117 0.005 977s 208 0.191 977s 398 0.654 977s 977s Contrast Correlation: 977s linear 977s linear 1 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s linear 1.054 0.146 977s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 977s Dose Response Model 977s 977s Model: sigEmax 977s Fit-type: general 977s 977s Coefficients dose-response model 977s eMax ed50 h 977s 0.4714 0.4880 0.5000 977s 977s Fitted to: 977s 1 2 3 4 977s 0.2846 0.2965 0.3502 0.3480 977s 977s Generalized residual sum of squares: 0.07825 977s Multiple Contrast Test 977s 977s Contrasts: 977s emax linear logistic linInt 977s 1 0.462 -0.429 0.511 -0.672 977s 2 0.505 0.002 0.507 0.437 977s 3 0.504 0.400 0.485 0.418 977s 4 0.527 0.810 0.497 0.428 977s 977s Contrast Correlation: 977s emax linear logistic linInt 977s emax 1.000 0.715 1.000 0.617 977s linear 0.715 1.000 0.698 0.863 977s logistic 1.000 0.698 1.000 0.598 977s linInt 0.617 0.863 0.598 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s emax 3.178 0.00193 977s logistic 3.164 0.00194 977s linear 2.640 0.00968 977s linInt 2.247 0.02721 977s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 977s Dose Response Model 977s 977s Model: sigEmax 977s Fit-type: general 977s 977s Coefficients dose-response model 977s eMax ed50 h 977s 0.4714 0.4880 0.5000 977s 977s Fitted to: 977s 3 4 1 2 977s 0.3502 0.3480 0.2846 0.2965 977s 977s Generalized residual sum of squares: 0.07825 977s Multiple Contrast Test 977s 977s Contrasts: 977s emax linear logistic linInt 977s 1 0.462 -0.429 0.511 -0.672 977s 2 0.505 0.002 0.507 0.437 977s 3 0.504 0.400 0.485 0.418 977s 4 0.527 0.810 0.497 0.428 977s 977s Contrast Correlation: 977s emax linear logistic linInt 977s emax 1.000 0.715 1.000 0.617 977s linear 0.715 1.000 0.698 0.863 977s logistic 1.000 0.698 1.000 0.598 977s linInt 0.617 0.863 0.598 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s emax 3.178 0.00213 977s logistic 3.164 0.00174 977s linear 2.640 0.00941 977s linInt 2.247 0.02663 977s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 977s Dose Response Model 977s 977s Model: sigEmax 977s Fit-type: general 977s 977s Coefficients dose-response model 977s e0 eMax ed50 h 977s 0.2171 0.4714 0.4860 0.5000 977s 977s Fitted to: 977s 0 1 2 3 4 977s 0.2169 0.5016 0.5138 0.5677 0.5648 977s 977s Generalized residual sum of squares: 0.07892 977s Multiple Contrast Test 977s 977s Contrasts: 977s emax linear logistic linInt 977s 0 -0.894 -0.617 -0.894 -0.522 977s 1 0.207 -0.338 0.228 -0.573 977s 2 0.226 0.002 0.227 0.373 977s 3 0.227 0.315 0.218 0.358 977s 4 0.235 0.637 0.221 0.363 977s 977s Contrast Correlation: 977s emax linear logistic linInt 977s emax 1.000 0.715 1.000 0.618 977s linear 0.715 1.000 0.698 0.863 977s logistic 1.000 0.698 1.000 0.599 977s linInt 0.618 0.863 0.599 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s emax 3.186 0.00184 977s logistic 3.172 0.00177 977s linear 2.645 0.00956 977s linInt 2.254 0.02649 977s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 977s Dose Response Model 977s 977s Model: sigEmax 977s Fit-type: general 977s 977s Coefficients dose-response model 977s e0 eMax ed50 h 977s 0.2171 0.4714 0.4860 0.5000 977s 977s Fitted to: 977s 2 3 0 1 4 977s 0.5138 0.5677 0.2169 0.5016 0.5648 977s 977s Generalized residual sum of squares: 0.07892 977s Multiple Contrast Test 977s 977s Contrasts: 977s emax linear logistic linInt 977s 0 -0.894 -0.617 -0.894 -0.522 977s 1 0.207 -0.338 0.228 -0.573 977s 2 0.226 0.002 0.227 0.373 977s 3 0.227 0.315 0.218 0.358 977s 4 0.235 0.637 0.221 0.363 977s 977s Contrast Correlation: 977s emax linear logistic linInt 977s emax 1.000 0.715 1.000 0.618 977s linear 0.715 1.000 0.698 0.863 977s logistic 1.000 0.698 1.000 0.599 977s linInt 0.618 0.863 0.599 1.000 977s 977s Multiple Contrast Test: 977s t-Stat adj-p 977s emax 3.186 0.00163 977s logistic 3.172 0.00192 977s linear 2.645 0.00981 977s linInt 2.254 0.02699 977s Warning messages: 977s 1: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 977s Warning from mvtnorm::pmvt: Covariance matrix not positive semidefinite. 977s 2: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 977s Setting calculated p-value to NA 977s [1] TRUE 977s testsMCT.R passed 977s Loading required package: DoseFinding 977s Loading required package: quadprog 977s Loading required package: Rsolnp 977s testsoptContr.R passed 977s testsplotDRMod.R consists only from comments and returns non-zero exit value ... ignored 977s testssampSize.R passed 977s Loading required package: DoseFinding 978s [1] 0.3076509 978s [1] 0.6153019 978s [1] 0.9229528 978s [1] 2.673503 978s [1] 0.7028559 978s [1] 2.064397 978s [1] NA 978s testssamplMod.R passed 979s /usr/bin/xdg-open: 1032: www-browser: not found 979s /usr/bin/xdg-open: 1032: links2: not found 979s /usr/bin/xdg-open: 1032: elinks: not found 979s /usr/bin/xdg-open: 1032: links: not found 979s /usr/bin/xdg-open: 1032: lynx: not found 979s /usr/bin/xdg-open: 1032: w3m: not found 979s xdg-open: no method available for opening 'https://huisophiesunrshiny.shinyapps.io/designmcpmod/' 979s [ FAIL 0 | WARN 0 | SKIP 0 | PASS 53 ] 979s testthat.R passed 979s autopkgtest [23:41:49]: test run-unit-test: -----------------------] 980s run-unit-test PASS 980s autopkgtest [23:41:50]: test run-unit-test: - - - - - - - - - - results - - - - - - - - - - 980s autopkgtest [23:41:50]: test pkg-r-autopkgtest: preparing testbed 980s Reading package lists... 980s Building dependency tree... 980s Reading state information... 980s Solving dependencies... 981s The following NEW packages will be installed: 981s build-essential cpp cpp-15 cpp-15-x86-64-linux-gnu cpp-x86-64-linux-gnu 981s dctrl-tools g++ g++-15 g++-15-x86-64-linux-gnu g++-x86-64-linux-gnu gcc 981s gcc-15 gcc-15-x86-64-linux-gnu gcc-x86-64-linux-gnu gfortran gfortran-15 981s gfortran-15-x86-64-linux-gnu gfortran-x86-64-linux-gnu icu-devtools libasan8 981s libblas-dev libbz2-dev libc-dev-bin libc6-dev libcc1-0 libcrypt-dev 981s libdeflate-dev libgcc-15-dev libgfortran-15-dev libhwasan0 libicu-dev 981s libisl23 libitm1 libjpeg-dev libjpeg-turbo8-dev libjpeg8-dev liblapack-dev 981s liblsan0 liblzma-dev libmpc3 libncurses-dev libpcre2-16-0 libpcre2-32-0 981s libpcre2-dev libpcre2-posix3 libpkgconf3 libpng-dev libquadmath0 981s libreadline-dev libstdc++-15-dev libtirpc-dev libtsan2 libubsan1 libzstd-dev 981s linux-libc-dev pkg-r-autopkgtest pkgconf pkgconf-bin r-base-dev rpcsvc-proto 981s zlib1g-dev 981s 0 upgraded, 61 newly installed, 0 to remove and 0 not upgraded. 981s Need to get 112 MB of archives. 981s After this operation, 401 MB of additional disk space will be used. 981s Get:1 http://ftpmaster.internal/ubuntu resolute/main amd64 libc-dev-bin amd64 2.42-2ubuntu4 [23.3 kB] 981s Get:2 http://ftpmaster.internal/ubuntu resolute/main amd64 linux-libc-dev amd64 6.19.0-3.3 [1846 kB] 984s Get:3 http://ftpmaster.internal/ubuntu resolute/main amd64 libcrypt-dev amd64 1:4.5.1-1 [122 kB] 984s Get:4 http://ftpmaster.internal/ubuntu resolute/main amd64 rpcsvc-proto amd64 1.4.3-1build1 [68.3 kB] 984s Get:5 http://ftpmaster.internal/ubuntu resolute/main amd64 libc6-dev amd64 2.42-2ubuntu4 [2207 kB] 989s Get:6 http://ftpmaster.internal/ubuntu resolute/main amd64 libisl23 amd64 0.27-1build1 [691 kB] 990s Get:7 http://ftpmaster.internal/ubuntu resolute/main amd64 libmpc3 amd64 1.3.1-2 [54.8 kB] 990s Get:8 http://ftpmaster.internal/ubuntu resolute/main amd64 cpp-15-x86-64-linux-gnu amd64 15.2.0-12ubuntu1 [12.9 MB] 1016s Get:9 http://ftpmaster.internal/ubuntu resolute/main amd64 cpp-15 amd64 15.2.0-12ubuntu1 [1034 B] 1016s Get:10 http://ftpmaster.internal/ubuntu resolute/main amd64 cpp-x86-64-linux-gnu amd64 4:15.2.0-4ubuntu1 [5746 B] 1016s Get:11 http://ftpmaster.internal/ubuntu resolute/main amd64 cpp amd64 4:15.2.0-4ubuntu1 [22.4 kB] 1016s Get:12 http://ftpmaster.internal/ubuntu resolute/main amd64 libcc1-0 amd64 15.2.0-12ubuntu1 [47.4 kB] 1016s Get:13 http://ftpmaster.internal/ubuntu resolute/main amd64 libitm1 amd64 15.2.0-12ubuntu1 [29.5 kB] 1016s Get:14 http://ftpmaster.internal/ubuntu resolute/main amd64 libasan8 amd64 15.2.0-12ubuntu1 [3070 kB] 1022s Get:15 http://ftpmaster.internal/ubuntu resolute/main amd64 liblsan0 amd64 15.2.0-12ubuntu1 [1360 kB] 1026s Get:16 http://ftpmaster.internal/ubuntu resolute/main amd64 libtsan2 amd64 15.2.0-12ubuntu1 [2757 kB] 1036s Get:17 http://ftpmaster.internal/ubuntu resolute/main amd64 libubsan1 amd64 15.2.0-12ubuntu1 [1210 kB] 1038s Get:18 http://ftpmaster.internal/ubuntu resolute/main amd64 libhwasan0 amd64 15.2.0-12ubuntu1 [1685 kB] 1042s Get:19 http://ftpmaster.internal/ubuntu resolute/main amd64 libquadmath0 amd64 15.2.0-12ubuntu1 [153 kB] 1042s Get:20 http://ftpmaster.internal/ubuntu resolute/main amd64 libgcc-15-dev amd64 15.2.0-12ubuntu1 [2866 kB] 1049s Get:21 http://ftpmaster.internal/ubuntu resolute/main amd64 gcc-15-x86-64-linux-gnu amd64 15.2.0-12ubuntu1 [25.4 MB] 1096s Get:22 http://ftpmaster.internal/ubuntu resolute/main amd64 gcc-15 amd64 15.2.0-12ubuntu1 [530 kB] 1097s Get:23 http://ftpmaster.internal/ubuntu resolute/main amd64 gcc-x86-64-linux-gnu amd64 4:15.2.0-4ubuntu1 [1208 B] 1097s Get:24 http://ftpmaster.internal/ubuntu resolute/main amd64 gcc amd64 4:15.2.0-4ubuntu1 [5024 B] 1097s Get:25 http://ftpmaster.internal/ubuntu resolute/main amd64 libstdc++-15-dev amd64 15.2.0-12ubuntu1 [2553 kB] 1101s Get:26 http://ftpmaster.internal/ubuntu resolute/main amd64 g++-15-x86-64-linux-gnu amd64 15.2.0-12ubuntu1 [14.4 MB] 1130s Get:27 http://ftpmaster.internal/ubuntu resolute/main amd64 g++-15 amd64 15.2.0-12ubuntu1 [25.3 kB] 1130s Get:28 http://ftpmaster.internal/ubuntu resolute/main amd64 g++-x86-64-linux-gnu amd64 4:15.2.0-4ubuntu1 [966 B] 1130s Get:29 http://ftpmaster.internal/ubuntu resolute/main amd64 g++ amd64 4:15.2.0-4ubuntu1 [1100 B] 1130s Get:30 http://ftpmaster.internal/ubuntu resolute/main amd64 build-essential amd64 12.12ubuntu2 [5256 B] 1130s Get:31 http://ftpmaster.internal/ubuntu resolute/main amd64 dctrl-tools amd64 2.24-3build4 [104 kB] 1130s Get:32 http://ftpmaster.internal/ubuntu resolute/main amd64 libgfortran-15-dev amd64 15.2.0-12ubuntu1 [973 kB] 1134s Get:33 http://ftpmaster.internal/ubuntu resolute/main amd64 gfortran-15-x86-64-linux-gnu amd64 15.2.0-12ubuntu1 [13.6 MB] 1170s Get:34 http://ftpmaster.internal/ubuntu resolute/main amd64 gfortran-15 amd64 15.2.0-12ubuntu1 [18.1 kB] 1170s Get:35 http://ftpmaster.internal/ubuntu resolute/main amd64 gfortran-x86-64-linux-gnu amd64 4:15.2.0-4ubuntu1 [1014 B] 1170s Get:36 http://ftpmaster.internal/ubuntu resolute/main amd64 gfortran amd64 4:15.2.0-4ubuntu1 [1172 B] 1170s Get:37 http://ftpmaster.internal/ubuntu resolute/main amd64 icu-devtools amd64 78.2-1ubuntu1 [214 kB] 1170s Get:38 http://ftpmaster.internal/ubuntu resolute/main amd64 libblas-dev amd64 3.12.1-7ubuntu1 [235 kB] 1170s Get:39 http://ftpmaster.internal/ubuntu resolute/main amd64 libbz2-dev amd64 1.0.8-6build2 [36.2 kB] 1170s Get:40 http://ftpmaster.internal/ubuntu resolute/main amd64 libdeflate-dev amd64 1.23-2build1 [58.8 kB] 1170s Get:41 http://ftpmaster.internal/ubuntu resolute/main amd64 libicu-dev amd64 78.2-1ubuntu1 [12.5 MB] 1194s Get:42 http://ftpmaster.internal/ubuntu resolute/main amd64 libjpeg-turbo8-dev amd64 2.1.5-4ubuntu3 [300 kB] 1194s Get:43 http://ftpmaster.internal/ubuntu resolute/main amd64 libjpeg8-dev amd64 8c-2ubuntu11 [1484 B] 1194s Get:44 http://ftpmaster.internal/ubuntu resolute/main amd64 libjpeg-dev amd64 8c-2ubuntu11 [1482 B] 1194s Get:45 http://ftpmaster.internal/ubuntu resolute/main amd64 liblapack-dev amd64 3.12.1-7ubuntu1 [5433 kB] 1204s Get:46 http://ftpmaster.internal/ubuntu resolute/main amd64 libncurses-dev amd64 6.6+20251231-1 [389 kB] 1204s Get:47 http://ftpmaster.internal/ubuntu resolute/main amd64 libpcre2-16-0 amd64 10.46-1 [243 kB] 1204s Get:48 http://ftpmaster.internal/ubuntu resolute/main amd64 libpcre2-32-0 amd64 10.46-1 [230 kB] 1204s Get:49 http://ftpmaster.internal/ubuntu resolute/main amd64 libpcre2-posix3 amd64 10.46-1 [7354 B] 1204s Get:50 http://ftpmaster.internal/ubuntu resolute/main amd64 libpcre2-dev amd64 10.46-1 [832 kB] 1205s Get:51 http://ftpmaster.internal/ubuntu resolute/main amd64 libpkgconf3 amd64 1.8.1-4build1 [32.8 kB] 1205s Get:52 http://ftpmaster.internal/ubuntu resolute/main amd64 zlib1g-dev amd64 1:1.3.dfsg+really1.3.1-1ubuntu2 [898 kB] 1207s Get:53 http://ftpmaster.internal/ubuntu resolute/main amd64 libpng-dev amd64 1.6.54-1 [273 kB] 1207s Get:54 http://ftpmaster.internal/ubuntu resolute/main amd64 libreadline-dev amd64 8.3-3 [189 kB] 1207s Get:55 http://ftpmaster.internal/ubuntu resolute/main amd64 libzstd-dev amd64 1.5.7+dfsg-3 [376 kB] 1207s Get:56 http://ftpmaster.internal/ubuntu resolute/main amd64 liblzma-dev amd64 5.8.2-2 [179 kB] 1207s Get:57 http://ftpmaster.internal/ubuntu resolute/main amd64 pkgconf-bin amd64 1.8.1-4build1 [21.7 kB] 1207s Get:58 http://ftpmaster.internal/ubuntu resolute/main amd64 pkgconf amd64 1.8.1-4build1 [16.8 kB] 1207s Get:59 http://ftpmaster.internal/ubuntu resolute/main amd64 libtirpc-dev amd64 1.3.6+ds-1 [195 kB] 1207s Get:60 http://ftpmaster.internal/ubuntu resolute/universe amd64 r-base-dev all 4.5.2-1ubuntu2 [1880 B] 1207s Get:61 http://ftpmaster.internal/ubuntu resolute/universe amd64 pkg-r-autopkgtest all 20250812 [6158 B] 1207s Fetched 112 MB in 3min 46s (493 kB/s) 1207s Selecting previously unselected package libc-dev-bin. 1207s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 142722 files and directories currently installed.) 1207s Preparing to unpack .../00-libc-dev-bin_2.42-2ubuntu4_amd64.deb ... 1207s Unpacking libc-dev-bin (2.42-2ubuntu4) ... 1207s Selecting previously unselected package linux-libc-dev:amd64. 1207s Preparing to unpack .../01-linux-libc-dev_6.19.0-3.3_amd64.deb ... 1207s Unpacking linux-libc-dev:amd64 (6.19.0-3.3) ... 1207s Selecting previously unselected package libcrypt-dev:amd64. 1207s Preparing to unpack .../02-libcrypt-dev_1%3a4.5.1-1_amd64.deb ... 1207s Unpacking libcrypt-dev:amd64 (1:4.5.1-1) ... 1207s Selecting previously unselected package rpcsvc-proto. 1207s Preparing to unpack .../03-rpcsvc-proto_1.4.3-1build1_amd64.deb ... 1207s Unpacking rpcsvc-proto (1.4.3-1build1) ... 1207s Selecting previously unselected package libc6-dev:amd64. 1207s Preparing to unpack .../04-libc6-dev_2.42-2ubuntu4_amd64.deb ... 1207s Unpacking libc6-dev:amd64 (2.42-2ubuntu4) ... 1207s Selecting previously unselected package libisl23:amd64. 1207s Preparing to unpack .../05-libisl23_0.27-1build1_amd64.deb ... 1207s Unpacking libisl23:amd64 (0.27-1build1) ... 1207s Selecting previously unselected package libmpc3:amd64. 1207s Preparing to unpack .../06-libmpc3_1.3.1-2_amd64.deb ... 1207s Unpacking libmpc3:amd64 (1.3.1-2) ... 1207s Selecting previously unselected package cpp-15-x86-64-linux-gnu. 1207s Preparing to unpack .../07-cpp-15-x86-64-linux-gnu_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking cpp-15-x86-64-linux-gnu (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package cpp-15. 1207s Preparing to unpack .../08-cpp-15_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking cpp-15 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package cpp-x86-64-linux-gnu. 1207s Preparing to unpack .../09-cpp-x86-64-linux-gnu_4%3a15.2.0-4ubuntu1_amd64.deb ... 1207s Unpacking cpp-x86-64-linux-gnu (4:15.2.0-4ubuntu1) ... 1207s Selecting previously unselected package cpp. 1207s Preparing to unpack .../10-cpp_4%3a15.2.0-4ubuntu1_amd64.deb ... 1207s Unpacking cpp (4:15.2.0-4ubuntu1) ... 1207s Selecting previously unselected package libcc1-0:amd64. 1207s Preparing to unpack .../11-libcc1-0_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libcc1-0:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libitm1:amd64. 1207s Preparing to unpack .../12-libitm1_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libitm1:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libasan8:amd64. 1207s Preparing to unpack .../13-libasan8_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libasan8:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package liblsan0:amd64. 1207s Preparing to unpack .../14-liblsan0_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking liblsan0:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libtsan2:amd64. 1207s Preparing to unpack .../15-libtsan2_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libtsan2:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libubsan1:amd64. 1207s Preparing to unpack .../16-libubsan1_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libubsan1:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libhwasan0:amd64. 1207s Preparing to unpack .../17-libhwasan0_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libhwasan0:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libquadmath0:amd64. 1207s Preparing to unpack .../18-libquadmath0_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libquadmath0:amd64 (15.2.0-12ubuntu1) ... 1207s Selecting previously unselected package libgcc-15-dev:amd64. 1207s Preparing to unpack .../19-libgcc-15-dev_15.2.0-12ubuntu1_amd64.deb ... 1207s Unpacking libgcc-15-dev:amd64 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gcc-15-x86-64-linux-gnu. 1208s Preparing to unpack .../20-gcc-15-x86-64-linux-gnu_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking gcc-15-x86-64-linux-gnu (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gcc-15. 1208s Preparing to unpack .../21-gcc-15_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking gcc-15 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gcc-x86-64-linux-gnu. 1208s Preparing to unpack .../22-gcc-x86-64-linux-gnu_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking gcc-x86-64-linux-gnu (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package gcc. 1208s Preparing to unpack .../23-gcc_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking gcc (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package libstdc++-15-dev:amd64. 1208s Preparing to unpack .../24-libstdc++-15-dev_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking libstdc++-15-dev:amd64 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package g++-15-x86-64-linux-gnu. 1208s Preparing to unpack .../25-g++-15-x86-64-linux-gnu_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking g++-15-x86-64-linux-gnu (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package g++-15. 1208s Preparing to unpack .../26-g++-15_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking g++-15 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package g++-x86-64-linux-gnu. 1208s Preparing to unpack .../27-g++-x86-64-linux-gnu_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking g++-x86-64-linux-gnu (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package g++. 1208s Preparing to unpack .../28-g++_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking g++ (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package build-essential. 1208s Preparing to unpack .../29-build-essential_12.12ubuntu2_amd64.deb ... 1208s Unpacking build-essential (12.12ubuntu2) ... 1208s Selecting previously unselected package dctrl-tools. 1208s Preparing to unpack .../30-dctrl-tools_2.24-3build4_amd64.deb ... 1208s Unpacking dctrl-tools (2.24-3build4) ... 1208s Selecting previously unselected package libgfortran-15-dev:amd64. 1208s Preparing to unpack .../31-libgfortran-15-dev_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking libgfortran-15-dev:amd64 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gfortran-15-x86-64-linux-gnu. 1208s Preparing to unpack .../32-gfortran-15-x86-64-linux-gnu_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking gfortran-15-x86-64-linux-gnu (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gfortran-15. 1208s Preparing to unpack .../33-gfortran-15_15.2.0-12ubuntu1_amd64.deb ... 1208s Unpacking gfortran-15 (15.2.0-12ubuntu1) ... 1208s Selecting previously unselected package gfortran-x86-64-linux-gnu. 1208s Preparing to unpack .../34-gfortran-x86-64-linux-gnu_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking gfortran-x86-64-linux-gnu (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package gfortran. 1208s Preparing to unpack .../35-gfortran_4%3a15.2.0-4ubuntu1_amd64.deb ... 1208s Unpacking gfortran (4:15.2.0-4ubuntu1) ... 1208s Selecting previously unselected package icu-devtools. 1208s Preparing to unpack .../36-icu-devtools_78.2-1ubuntu1_amd64.deb ... 1208s Unpacking icu-devtools (78.2-1ubuntu1) ... 1208s Selecting previously unselected package libblas-dev:amd64. 1208s Preparing to unpack .../37-libblas-dev_3.12.1-7ubuntu1_amd64.deb ... 1208s Unpacking libblas-dev:amd64 (3.12.1-7ubuntu1) ... 1208s Selecting previously unselected package libbz2-dev:amd64. 1208s Preparing to unpack .../38-libbz2-dev_1.0.8-6build2_amd64.deb ... 1208s Unpacking libbz2-dev:amd64 (1.0.8-6build2) ... 1208s Selecting previously unselected package libdeflate-dev:amd64. 1208s Preparing to unpack .../39-libdeflate-dev_1.23-2build1_amd64.deb ... 1208s Unpacking libdeflate-dev:amd64 (1.23-2build1) ... 1208s Selecting previously unselected package libicu-dev:amd64. 1208s Preparing to unpack .../40-libicu-dev_78.2-1ubuntu1_amd64.deb ... 1208s Unpacking libicu-dev:amd64 (78.2-1ubuntu1) ... 1208s Selecting previously unselected package libjpeg-turbo8-dev:amd64. 1208s Preparing to unpack .../41-libjpeg-turbo8-dev_2.1.5-4ubuntu3_amd64.deb ... 1208s Unpacking libjpeg-turbo8-dev:amd64 (2.1.5-4ubuntu3) ... 1208s Selecting previously unselected package libjpeg8-dev:amd64. 1208s Preparing to unpack .../42-libjpeg8-dev_8c-2ubuntu11_amd64.deb ... 1208s Unpacking libjpeg8-dev:amd64 (8c-2ubuntu11) ... 1208s Selecting previously unselected package libjpeg-dev:amd64. 1209s Preparing to unpack .../43-libjpeg-dev_8c-2ubuntu11_amd64.deb ... 1209s Unpacking libjpeg-dev:amd64 (8c-2ubuntu11) ... 1209s Selecting previously unselected package liblapack-dev:amd64. 1209s Preparing to unpack .../44-liblapack-dev_3.12.1-7ubuntu1_amd64.deb ... 1209s Unpacking liblapack-dev:amd64 (3.12.1-7ubuntu1) ... 1209s Selecting previously unselected package libncurses-dev:amd64. 1209s Preparing to unpack .../45-libncurses-dev_6.6+20251231-1_amd64.deb ... 1209s Unpacking libncurses-dev:amd64 (6.6+20251231-1) ... 1209s Selecting previously unselected package libpcre2-16-0:amd64. 1209s Preparing to unpack .../46-libpcre2-16-0_10.46-1_amd64.deb ... 1209s Unpacking libpcre2-16-0:amd64 (10.46-1) ... 1209s Selecting previously unselected package libpcre2-32-0:amd64. 1209s Preparing to unpack .../47-libpcre2-32-0_10.46-1_amd64.deb ... 1209s Unpacking libpcre2-32-0:amd64 (10.46-1) ... 1209s Selecting previously unselected package libpcre2-posix3:amd64. 1209s Preparing to unpack .../48-libpcre2-posix3_10.46-1_amd64.deb ... 1209s Unpacking libpcre2-posix3:amd64 (10.46-1) ... 1209s Selecting previously unselected package libpcre2-dev:amd64. 1209s Preparing to unpack .../49-libpcre2-dev_10.46-1_amd64.deb ... 1209s Unpacking libpcre2-dev:amd64 (10.46-1) ... 1209s Selecting previously unselected package libpkgconf3:amd64. 1209s Preparing to unpack .../50-libpkgconf3_1.8.1-4build1_amd64.deb ... 1209s Unpacking libpkgconf3:amd64 (1.8.1-4build1) ... 1209s Selecting previously unselected package zlib1g-dev:amd64. 1209s Preparing to unpack .../51-zlib1g-dev_1%3a1.3.dfsg+really1.3.1-1ubuntu2_amd64.deb ... 1209s Unpacking zlib1g-dev:amd64 (1:1.3.dfsg+really1.3.1-1ubuntu2) ... 1209s Selecting previously unselected package libpng-dev:amd64. 1209s Preparing to unpack .../52-libpng-dev_1.6.54-1_amd64.deb ... 1209s Unpacking libpng-dev:amd64 (1.6.54-1) ... 1209s Selecting previously unselected package libreadline-dev:amd64. 1209s Preparing to unpack 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1209s Setting up libubsan1:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libpcre2-posix3:amd64 (10.46-1) ... 1209s Setting up libhwasan0:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libcrypt-dev:amd64 (1:4.5.1-1) ... 1209s Setting up libasan8:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libtsan2:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libisl23:amd64 (0.27-1build1) ... 1209s Setting up libc-dev-bin (2.42-2ubuntu4) ... 1209s Setting up libdeflate-dev:amd64 (1.23-2build1) ... 1209s Setting up libcc1-0:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up liblsan0:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libblas-dev:amd64 (3.12.1-7ubuntu1) ... 1209s update-alternatives: using /usr/lib/x86_64-linux-gnu/blas/libblas.so to provide /usr/lib/x86_64-linux-gnu/libblas.so (libblas.so-x86_64-linux-gnu) in auto mode 1209s Setting up dctrl-tools (2.24-3build4) ... 1209s Setting up libitm1:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up libgcc-15-dev:amd64 (15.2.0-12ubuntu1) ... 1209s Setting up 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skip creation of /usr/share/man/man1/f95.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f95) doesn't exist 1209s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f77 (f77) in auto mode 1209s update-alternatives: warning: skip creation of /usr/share/man/man1/f77.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f77) doesn't exist 1209s Setting up g++ (4:15.2.0-4ubuntu1) ... 1209s update-alternatives: using /usr/bin/g++ to provide /usr/bin/c++ (c++) in auto mode 1209s Setting up build-essential (12.12ubuntu2) ... 1209s Setting up r-base-dev (4.5.2-1ubuntu2) ... 1209s Setting up pkg-r-autopkgtest (20250812) ... 1209s Processing triggers for libc-bin (2.42-2ubuntu4) ... 1209s Processing triggers for man-db (2.13.1-1build1) ... 1210s Processing triggers for install-info (7.2-5) ... 1210s autopkgtest [23:45:40]: test pkg-r-autopkgtest: /usr/share/dh-r/pkg-r-autopkgtest 1210s autopkgtest [23:45:40]: test pkg-r-autopkgtest: [----------------------- 1211s Test: Try to load the R library DoseFinding 1211s 1211s R version 4.5.2 (2025-10-31) -- "[Not] Part in a Rumble" 1211s Copyright (C) 2025 The R Foundation for Statistical Computing 1211s Platform: x86_64-pc-linux-gnu 1211s 1211s R is free software and comes with ABSOLUTELY NO WARRANTY. 1211s You are welcome to redistribute it under certain conditions. 1211s Type 'license()' or 'licence()' for distribution details. 1211s 1211s R is a collaborative project with many contributors. 1211s Type 'contributors()' for more information and 1211s 'citation()' on how to cite R or R packages in publications. 1211s 1211s Type 'demo()' for some demos, 'help()' for on-line help, or 1211s 'help.start()' for an HTML browser interface to help. 1211s Type 'q()' to quit R. 1211s 1211s > library('DoseFinding') 1211s > 1211s autopkgtest [23:45:41]: test pkg-r-autopkgtest: -----------------------] 1212s pkg-r-autopkgtest PASS 1212s autopkgtest [23:45:42]: test pkg-r-autopkgtest: - - - - - - - - - - results - - - - - - - - - - 1212s autopkgtest [23:45:42]: @@@@@@@@@@@@@@@@@@@@ summary 1212s run-unit-test PASS 1212s pkg-r-autopkgtest PASS