0s autopkgtest [15:23:47]: starting date and time: 2025-03-15 15:23:47+0000 0s autopkgtest [15:23:47]: git checkout: 325255d2 Merge branch 'pin-any-arch' into 'ubuntu/production' 0s autopkgtest [15:23:47]: host juju-7f2275-prod-proposed-migration-environment-15; command line: /home/ubuntu/autopkgtest/runner/autopkgtest --output-dir /tmp/autopkgtest-work.gyxwcna_/out --timeout-copy=6000 --setup-commands /home/ubuntu/autopkgtest-cloud/worker-config-production/setup-canonical.sh --apt-pocket=proposed=src:glibc --apt-upgrade r-cran-dosefinding --timeout-short=300 --timeout-copy=20000 --timeout-build=20000 --env=ADT_TEST_TRIGGERS=glibc/2.41-1ubuntu2 -- ssh -s /home/ubuntu/autopkgtest/ssh-setup/nova -- --flavor autopkgtest --security-groups autopkgtest-juju-7f2275-prod-proposed-migration-environment-15@bos03-arm64-12.secgroup --name adt-plucky-arm64-r-cran-dosefinding-20250315-152345-juju-7f2275-prod-proposed-migration-environment-15-ae110736-73de-477b-a603-4c58cee7a008 --image adt/ubuntu-plucky-arm64-server --keyname testbed-juju-7f2275-prod-proposed-migration-environment-15 --net-id=net_prod-proposed-migration -e TERM=linux -e ''"'"'http_proxy=http://squid.internal:3128'"'"'' -e ''"'"'https_proxy=http://squid.internal:3128'"'"'' -e ''"'"'no_proxy=127.0.0.1,127.0.1.1,login.ubuntu.com,localhost,localdomain,novalocal,internal,archive.ubuntu.com,ports.ubuntu.com,security.ubuntu.com,ddebs.ubuntu.com,changelogs.ubuntu.com,keyserver.ubuntu.com,launchpadlibrarian.net,launchpadcontent.net,launchpad.net,10.24.0.0/24,keystone.ps5.canonical.com,objectstorage.prodstack5.canonical.com,radosgw.ps5.canonical.com'"'"'' --mirror=http://ftpmaster.internal/ubuntu/ 137s autopkgtest [15:26:04]: testbed dpkg architecture: arm64 137s autopkgtest [15:26:04]: testbed apt version: 2.9.33 137s autopkgtest [15:26:04]: @@@@@@@@@@@@@@@@@@@@ test bed setup 138s autopkgtest [15:26:05]: testbed release detected to be: None 138s autopkgtest [15:26:05]: updating testbed package index (apt update) 139s Get:1 http://ftpmaster.internal/ubuntu plucky-proposed InRelease [126 kB] 139s Hit:2 http://ftpmaster.internal/ubuntu plucky InRelease 140s Hit:3 http://ftpmaster.internal/ubuntu plucky-updates InRelease 140s Hit:4 http://ftpmaster.internal/ubuntu plucky-security InRelease 140s Get:5 http://ftpmaster.internal/ubuntu plucky-proposed/universe Sources [404 kB] 140s Get:6 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse Sources [15.8 kB] 140s Get:7 http://ftpmaster.internal/ubuntu plucky-proposed/main Sources [101 kB] 140s Get:8 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 Packages [78.2 kB] 140s Get:9 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 c-n-f Metadata [1976 B] 140s Get:10 http://ftpmaster.internal/ubuntu plucky-proposed/restricted arm64 c-n-f Metadata [116 B] 140s Get:11 http://ftpmaster.internal/ubuntu plucky-proposed/universe arm64 Packages [346 kB] 141s Get:12 http://ftpmaster.internal/ubuntu plucky-proposed/universe arm64 c-n-f Metadata [15.8 kB] 141s Get:13 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse arm64 Packages [4948 B] 141s Get:14 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse arm64 c-n-f Metadata [572 B] 141s Fetched 1094 kB in 2s (535 kB/s) 142s Reading package lists... 143s + lsb_release --codename --short 143s + RELEASE=plucky 143s + cat 143s + [ plucky != trusty ] 143s + DEBIAN_FRONTEND=noninteractive eatmydata apt-get -y --allow-downgrades -o Dpkg::Options::=--force-confnew dist-upgrade 143s Reading package lists... 143s Building dependency tree... 143s Reading state information... 144s Calculating upgrade... 144s Calculating upgrade... 145s The following packages will be upgraded: 145s python3-jinja2 strace 145s 2 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 145s Need to get 608 kB of archives. 145s After this operation, 11.3 kB of additional disk space will be used. 145s Get:1 http://ftpmaster.internal/ubuntu plucky/main arm64 strace arm64 6.13+ds-1ubuntu1 [499 kB] 146s Get:2 http://ftpmaster.internal/ubuntu plucky/main arm64 python3-jinja2 all 3.1.5-2ubuntu1 [109 kB] 146s Fetched 608 kB in 1s (573 kB/s) 147s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 117701 files and directories currently installed.) 147s Preparing to unpack .../strace_6.13+ds-1ubuntu1_arm64.deb ... 147s Unpacking strace (6.13+ds-1ubuntu1) over (6.11-0ubuntu1) ... 147s Preparing to unpack .../python3-jinja2_3.1.5-2ubuntu1_all.deb ... 147s Unpacking python3-jinja2 (3.1.5-2ubuntu1) over (3.1.5-2) ... 147s Setting up python3-jinja2 (3.1.5-2ubuntu1) ... 147s Setting up strace (6.13+ds-1ubuntu1) ... 147s Processing triggers for man-db (2.13.0-1) ... 148s + rm /etc/apt/preferences.d/force-downgrade-to-release.pref 148s + /usr/lib/apt/apt-helper analyze-pattern ?true 148s + uname -r 148s + sed s/\./\\./g 148s + running_kernel_pattern=^linux-.*6\.14\.0-10-generic.* 148s + apt list ?obsolete 148s + tail -n+2 148s + cut -d/ -f1 148s + grep -v ^linux-.*6\.14\.0-10-generic.* 148s + obsolete_pkgs=linux-headers-6.11.0-8-generic 148s linux-headers-6.11.0-8 148s linux-image-6.11.0-8-generic 148s linux-modules-6.11.0-8-generic 148s linux-tools-6.11.0-8-generic 148s linux-tools-6.11.0-8 148s + DEBIAN_FRONTEND=noninteractive eatmydata apt-get -y purge --autoremove linux-headers-6.11.0-8-generic linux-headers-6.11.0-8 linux-image-6.11.0-8-generic linux-modules-6.11.0-8-generic linux-tools-6.11.0-8-generic linux-tools-6.11.0-8 148s Reading package lists... 149s Building dependency tree... 149s Reading state information... 150s Solving dependencies... 151s The following packages will be REMOVED: 151s libnsl2* libpython3.12-minimal* libpython3.12-stdlib* libpython3.12t64* 151s libunwind8* linux-headers-6.11.0-8* linux-headers-6.11.0-8-generic* 151s linux-image-6.11.0-8-generic* linux-modules-6.11.0-8-generic* 151s linux-tools-6.11.0-8* linux-tools-6.11.0-8-generic* 152s 0 upgraded, 0 newly installed, 11 to remove and 5 not upgraded. 152s After this operation, 267 MB disk space will be freed. 152s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 117701 files and directories currently installed.) 152s Removing linux-tools-6.11.0-8-generic (6.11.0-8.8) ... 152s Removing linux-tools-6.11.0-8 (6.11.0-8.8) ... 152s Removing libpython3.12t64:arm64 (3.12.9-1) ... 152s Removing libpython3.12-stdlib:arm64 (3.12.9-1) ... 152s Removing libnsl2:arm64 (1.3.0-3build3) ... 152s Removing libpython3.12-minimal:arm64 (3.12.9-1) ... 152s Removing libunwind8:arm64 (1.6.2-3.1) ... 152s Removing linux-headers-6.11.0-8-generic (6.11.0-8.8) ... 153s Removing linux-headers-6.11.0-8 (6.11.0-8.8) ... 154s Removing linux-image-6.11.0-8-generic (6.11.0-8.8) ... 154s I: /boot/vmlinuz.old is now a symlink to vmlinuz-6.14.0-10-generic 154s I: /boot/initrd.img.old is now a symlink to initrd.img-6.14.0-10-generic 154s /etc/kernel/postrm.d/initramfs-tools: 154s update-initramfs: Deleting /boot/initrd.img-6.11.0-8-generic 155s /etc/kernel/postrm.d/zz-flash-kernel: 155s flash-kernel: Kernel 6.11.0-8-generic has been removed. 155s flash-kernel: A higher version (6.14.0-10-generic) is still installed, no reflashing required. 155s /etc/kernel/postrm.d/zz-update-grub: 155s Sourcing file `/etc/default/grub' 155s Sourcing file `/etc/default/grub.d/50-cloudimg-settings.cfg' 155s Generating grub configuration file ... 155s Found linux image: /boot/vmlinuz-6.14.0-10-generic 155s Found initrd image: /boot/initrd.img-6.14.0-10-generic 156s Warning: os-prober will not be executed to detect other bootable partitions. 156s Systems on them will not be added to the GRUB boot configuration. 156s Check GRUB_DISABLE_OS_PROBER documentation entry. 156s Adding boot menu entry for UEFI Firmware Settings ... 156s done 156s Removing linux-modules-6.11.0-8-generic (6.11.0-8.8) ... 156s Processing triggers for libc-bin (2.41-1ubuntu1) ... 156s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 81650 files and directories currently installed.) 156s Purging configuration files for linux-image-6.11.0-8-generic (6.11.0-8.8) ... 157s Purging configuration files for libpython3.12-minimal:arm64 (3.12.9-1) ... 157s Purging configuration files for linux-modules-6.11.0-8-generic (6.11.0-8.8) ... 157s + grep -q trusty /etc/lsb-release 157s + [ ! -d /usr/share/doc/unattended-upgrades ] 157s + [ ! -d /usr/share/doc/lxd ] 157s + [ ! -d /usr/share/doc/lxd-client ] 157s + [ ! -d /usr/share/doc/snapd ] 157s + type iptables 157s + cat 157s + chmod 755 /etc/rc.local 157s + . /etc/rc.local 157s + iptables -w -t mangle -A FORWARD -p tcp --tcp-flags SYN,RST SYN -j TCPMSS --clamp-mss-to-pmtu 157s + iptables -A OUTPUT -d 10.255.255.1/32 -p tcp -j DROP 157s + iptables -A OUTPUT -d 10.255.255.2/32 -p tcp -j DROP 157s + uname -m 157s + [ aarch64 = ppc64le ] 157s + [ -d /run/systemd/system ] 157s + systemd-detect-virt --quiet --vm 157s + mkdir -p /etc/systemd/system/systemd-random-seed.service.d/ 157s + cat 157s + grep -q lz4 /etc/initramfs-tools/initramfs.conf 157s + echo COMPRESS=lz4 157s autopkgtest [15:26:24]: upgrading testbed (apt dist-upgrade and autopurge) 157s Reading package lists... 158s Building dependency tree... 158s Reading state information... 159s Calculating upgrade...Starting pkgProblemResolver with broken count: 0 159s Starting 2 pkgProblemResolver with broken count: 0 159s Done 161s Entering ResolveByKeep 162s 162s Calculating upgrade... 163s The following packages will be upgraded: 163s libc-bin libc-dev-bin libc6 libc6-dev locales 163s 5 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 163s Need to get 9530 kB of archives. 163s After this operation, 0 B of additional disk space will be used. 163s Get:1 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 libc6-dev arm64 2.41-1ubuntu2 [1750 kB] 165s Get:2 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 libc-dev-bin arm64 2.41-1ubuntu2 [24.0 kB] 165s Get:3 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 libc6 arm64 2.41-1ubuntu2 [2910 kB] 168s Get:4 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 libc-bin arm64 2.41-1ubuntu2 [600 kB] 168s Get:5 http://ftpmaster.internal/ubuntu plucky-proposed/main arm64 locales all 2.41-1ubuntu2 [4246 kB] 173s Preconfiguring packages ... 173s Fetched 9530 kB in 9s (1045 kB/s) 173s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 81647 files and directories currently installed.) 173s Preparing to unpack .../libc6-dev_2.41-1ubuntu2_arm64.deb ... 173s Unpacking libc6-dev:arm64 (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 173s Preparing to unpack .../libc-dev-bin_2.41-1ubuntu2_arm64.deb ... 173s Unpacking libc-dev-bin (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 173s Preparing to unpack .../libc6_2.41-1ubuntu2_arm64.deb ... 173s Unpacking libc6:arm64 (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 174s Setting up libc6:arm64 (2.41-1ubuntu2) ... 174s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 81647 files and directories currently installed.) 174s Preparing to unpack .../libc-bin_2.41-1ubuntu2_arm64.deb ... 174s Unpacking libc-bin (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 174s Setting up libc-bin (2.41-1ubuntu2) ... 174s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 81647 files and directories currently installed.) 174s Preparing to unpack .../locales_2.41-1ubuntu2_all.deb ... 174s Unpacking locales (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 174s Setting up locales (2.41-1ubuntu2) ... 176s Generating locales (this might take a while)... 180s en_US.UTF-8... done 180s Generation complete. 180s Setting up libc-dev-bin (2.41-1ubuntu2) ... 180s Setting up libc6-dev:arm64 (2.41-1ubuntu2) ... 180s Processing triggers for man-db (2.13.0-1) ... 181s Processing triggers for systemd (257.3-1ubuntu3) ... 182s Reading package lists... 182s Building dependency tree... 182s Reading state information... 183s Starting pkgProblemResolver with broken count: 0 184s Starting 2 pkgProblemResolver with broken count: 0 184s Done 184s Solving dependencies... 186s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 186s autopkgtest [15:26:53]: rebooting testbed after setup commands that affected boot 208s autopkgtest-virt-ssh: WARNING: ssh connection failed. Retrying in 3 seconds... 216s autopkgtest [15:27:23]: testbed running kernel: Linux 6.14.0-10-generic #10-Ubuntu SMP PREEMPT_DYNAMIC Wed Mar 12 15:45:31 UTC 2025 219s autopkgtest [15:27:26]: @@@@@@@@@@@@@@@@@@@@ apt-source r-cran-dosefinding 222s Get:1 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (dsc) [2322 B] 222s Get:2 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (tar) [698 kB] 222s Get:3 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (diff) [4244 B] 222s gpgv: Signature made Fri Mar 14 00:07:33 2025 UTC 222s gpgv: using RSA key 73471499CC60ED9EEE805946C5BD6C8F2295D502 222s gpgv: issuer "plessy@debian.org" 222s gpgv: Can't check signature: No public key 222s dpkg-source: warning: cannot verify inline signature for ./r-cran-dosefinding_1.3-1-1.dsc: no acceptable signature found 223s autopkgtest [15:27:30]: testing package r-cran-dosefinding version 1.3-1-1 223s autopkgtest [15:27:30]: build not needed 225s autopkgtest [15:27:32]: test run-unit-test: preparing testbed 226s Reading package lists... 226s Building dependency tree... 226s Reading state information... 226s Starting pkgProblemResolver with broken count: 0 227s Starting 2 pkgProblemResolver with broken count: 0 227s Done 227s The following NEW packages will be installed: 227s fontconfig fontconfig-config fonts-dejavu-core fonts-dejavu-mono 227s fonts-font-awesome fonts-glyphicons-halflings fonts-mathjax 227s javascript-common libblas3 libcairo2 libdatrie1 libdeflate0 libfontconfig1 227s libgfortran5 libgomp1 libgraphite2-3 libharfbuzz0b libice6 libjbig0 227s libjpeg-turbo8 libjpeg8 libjs-bootstrap libjs-bootstrap4 libjs-d3 227s libjs-es5-shim libjs-highlight.js libjs-jquery libjs-jquery-datatables 227s libjs-jquery-selectize.js libjs-jquery-ui libjs-json libjs-mathjax 227s libjs-microplugin.js libjs-modernizr libjs-popper.js libjs-prettify 227s libjs-sifter.js libjs-twitter-bootstrap-datepicker liblapack3 liblerc4 227s liblua5.4-0 libpango-1.0-0 libpangocairo-1.0-0 libpangoft2-1.0-0 227s libpaper-utils libpaper2 libpixman-1-0 libsharpyuv0 libsm6 libtcl8.6 227s libthai-data libthai0 libtiff6 libtk8.6 libwebp7 libxcb-render0 libxcb-shm0 227s libxft2 libxrender1 libxss1 libxt6t64 littler node-bootstrap-sass 227s node-html5shiv node-normalize.css pandoc pandoc-data r-base-core 227s r-cran-base64enc r-cran-brio r-cran-bslib r-cran-cachem r-cran-callr 227s r-cran-cli r-cran-codetools r-cran-colorspace r-cran-commonmark 227s r-cran-crayon r-cran-desc r-cran-diffobj r-cran-digest r-cran-dosefinding 227s r-cran-evaluate r-cran-fansi r-cran-farver r-cran-fastmap r-cran-fontawesome 227s r-cran-fs r-cran-ggplot2 r-cran-glue r-cran-gtable r-cran-highr 227s r-cran-htmltools r-cran-httpuv r-cran-isoband r-cran-jquerylib 227s r-cran-jsonlite r-cran-knitr r-cran-labeling r-cran-later r-cran-lattice 227s r-cran-lifecycle r-cran-littler r-cran-magrittr r-cran-mass r-cran-matrix 227s r-cran-memoise r-cran-mgcv r-cran-mime r-cran-multcomp r-cran-munsell 227s r-cran-mvtnorm r-cran-nlme r-cran-numderiv r-cran-pillar r-cran-pkgbuild 227s r-cran-pkgconfig r-cran-pkgkitten r-cran-pkgload r-cran-praise 227s r-cran-processx r-cran-promises r-cran-ps r-cran-quadprog r-cran-r6 227s r-cran-rappdirs r-cran-rcolorbrewer r-cran-rcpp r-cran-rlang 227s r-cran-rmarkdown r-cran-rprojroot r-cran-rsolnp r-cran-sandwich r-cran-sass 227s r-cran-scales r-cran-shiny r-cran-sourcetools r-cran-survival 227s r-cran-testthat r-cran-th.data r-cran-tibble r-cran-tinytex r-cran-truncnorm 227s r-cran-utf8 r-cran-vctrs r-cran-viridislite r-cran-waldo r-cran-withr 227s r-cran-xfun r-cran-xtable r-cran-yaml r-cran-zoo unzip x11-common xdg-utils 227s zip 228s 0 upgraded, 156 newly installed, 0 to remove and 0 not upgraded. 228s Need to get 153 MB of archives. 228s After this operation, 490 MB of additional disk space will be used. 228s Get:1 http://ftpmaster.internal/ubuntu plucky/main arm64 fonts-dejavu-mono all 2.37-8 [502 kB] 228s Get:2 http://ftpmaster.internal/ubuntu plucky/main arm64 fonts-dejavu-core all 2.37-8 [835 kB] 229s Get:3 http://ftpmaster.internal/ubuntu plucky/main arm64 fontconfig-config arm64 2.15.0-2ubuntu1 [37.5 kB] 229s Get:4 http://ftpmaster.internal/ubuntu plucky/main arm64 libfontconfig1 arm64 2.15.0-2ubuntu1 [144 kB] 229s Get:5 http://ftpmaster.internal/ubuntu plucky/main arm64 fontconfig arm64 2.15.0-2ubuntu1 [191 kB] 229s Get:6 http://ftpmaster.internal/ubuntu plucky/main arm64 fonts-font-awesome all 5.0.10+really4.7.0~dfsg-4.1 [516 kB] 229s Get:7 http://ftpmaster.internal/ubuntu plucky/universe arm64 fonts-glyphicons-halflings all 1.009~3.4.1+dfsg-3 [118 kB] 229s Get:8 http://ftpmaster.internal/ubuntu plucky/main arm64 fonts-mathjax all 2.7.9+dfsg-1 [2208 kB] 231s Get:9 http://ftpmaster.internal/ubuntu plucky/main arm64 javascript-common all 12 [5216 B] 231s Get:10 http://ftpmaster.internal/ubuntu plucky/main arm64 libblas3 arm64 3.12.1-2 [161 kB] 231s Get:11 http://ftpmaster.internal/ubuntu plucky/main arm64 libpixman-1-0 arm64 0.44.0-3 [197 kB] 231s Get:12 http://ftpmaster.internal/ubuntu plucky/main arm64 libxcb-render0 arm64 1.17.0-2 [16.6 kB] 231s Get:13 http://ftpmaster.internal/ubuntu plucky/main arm64 libxcb-shm0 arm64 1.17.0-2 [5884 B] 231s Get:14 http://ftpmaster.internal/ubuntu plucky/main arm64 libxrender1 arm64 1:0.9.10-1.1build1 [18.8 kB] 231s Get:15 http://ftpmaster.internal/ubuntu plucky/main arm64 libcairo2 arm64 1.18.2-2 [560 kB] 232s Get:16 http://ftpmaster.internal/ubuntu plucky/main arm64 libdatrie1 arm64 0.2.13-3build1 [19.2 kB] 232s Get:17 http://ftpmaster.internal/ubuntu plucky/main arm64 libdeflate0 arm64 1.23-1 [46.2 kB] 232s Get:18 http://ftpmaster.internal/ubuntu plucky/main arm64 libgfortran5 arm64 15-20250222-0ubuntu1 [444 kB] 232s Get:19 http://ftpmaster.internal/ubuntu plucky/main arm64 libgomp1 arm64 15-20250222-0ubuntu1 [146 kB] 232s Get:20 http://ftpmaster.internal/ubuntu plucky/main arm64 libgraphite2-3 arm64 1.3.14-2ubuntu1 [70.6 kB] 232s Get:21 http://ftpmaster.internal/ubuntu plucky/main arm64 libharfbuzz0b arm64 10.2.0-1 [490 kB] 232s Get:22 http://ftpmaster.internal/ubuntu plucky/main arm64 x11-common all 1:7.7+23ubuntu3 [21.7 kB] 232s Get:23 http://ftpmaster.internal/ubuntu plucky/main arm64 libice6 arm64 2:1.1.1-1 [42.3 kB] 232s Get:24 http://ftpmaster.internal/ubuntu plucky/main arm64 libjpeg-turbo8 arm64 2.1.5-3ubuntu2 [165 kB] 233s Get:25 http://ftpmaster.internal/ubuntu plucky/main arm64 libjpeg8 arm64 8c-2ubuntu11 [2148 B] 233s Get:26 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-bootstrap all 3.4.1+dfsg-3 [129 kB] 233s Get:27 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-popper.js all 1.16.1+ds-6 [54.1 kB] 233s Get:28 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-bootstrap4 all 4.6.1+dfsg1-4 [537 kB] 233s Get:29 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-d3 all 3.5.17-4 [132 kB] 233s Get:30 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-es5-shim all 4.6.7-2 [39.8 kB] 233s Get:31 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-highlight.js all 9.18.5+dfsg1-2 [385 kB] 234s Get:32 http://ftpmaster.internal/ubuntu plucky/main arm64 libjs-jquery all 3.6.1+dfsg+~3.5.14-1 [328 kB] 234s Get:33 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-jquery-datatables all 1.11.5+dfsg-2 [146 kB] 234s Get:34 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-sifter.js all 0.6.0+dfsg-3 [12.6 kB] 234s Get:35 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-microplugin.js all 0.0.3+dfsg-1.1 [3712 B] 234s Get:36 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-jquery-selectize.js all 0.12.6+dfsg-1.1 [51.0 kB] 234s Get:37 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-jquery-ui all 1.13.2+dfsg-1 [252 kB] 234s Get:38 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-json all 0~20221030+~1.0.8-1 [20.6 kB] 234s Get:39 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-prettify all 2015.12.04+dfsg-1.1 [39.3 kB] 234s Get:40 http://ftpmaster.internal/ubuntu plucky/main arm64 liblapack3 arm64 3.12.1-2 [2307 kB] 236s Get:41 http://ftpmaster.internal/ubuntu plucky/main arm64 liblerc4 arm64 4.0.0+ds-5ubuntu1 [167 kB] 236s Get:42 http://ftpmaster.internal/ubuntu plucky/main arm64 liblua5.4-0 arm64 5.4.7-1 [158 kB] 236s Get:43 http://ftpmaster.internal/ubuntu plucky/main arm64 libthai-data all 0.1.29-2build1 [158 kB] 237s Get:44 http://ftpmaster.internal/ubuntu plucky/main arm64 libthai0 arm64 0.1.29-2build1 [18.2 kB] 237s Get:45 http://ftpmaster.internal/ubuntu plucky/main arm64 libpango-1.0-0 arm64 1.56.2-1 [237 kB] 237s Get:46 http://ftpmaster.internal/ubuntu plucky/main arm64 libpangoft2-1.0-0 arm64 1.56.2-1 [49.5 kB] 237s Get:47 http://ftpmaster.internal/ubuntu plucky/main arm64 libpangocairo-1.0-0 arm64 1.56.2-1 [27.6 kB] 237s Get:48 http://ftpmaster.internal/ubuntu plucky/main arm64 libpaper2 arm64 2.2.5-0.3 [17.3 kB] 237s Get:49 http://ftpmaster.internal/ubuntu plucky/main arm64 libpaper-utils arm64 2.2.5-0.3 [15.4 kB] 237s Get:50 http://ftpmaster.internal/ubuntu plucky/main arm64 libsharpyuv0 arm64 1.5.0-0.1 [16.9 kB] 237s Get:51 http://ftpmaster.internal/ubuntu plucky/main arm64 libsm6 arm64 2:1.2.4-1 [16.4 kB] 237s Get:52 http://ftpmaster.internal/ubuntu plucky/main arm64 libtcl8.6 arm64 8.6.16+dfsg-1 [987 kB] 238s Get:53 http://ftpmaster.internal/ubuntu plucky/main arm64 libjbig0 arm64 2.1-6.1ubuntu2 [29.3 kB] 238s Get:54 http://ftpmaster.internal/ubuntu plucky/main arm64 libwebp7 arm64 1.5.0-0.1 [194 kB] 238s Get:55 http://ftpmaster.internal/ubuntu plucky/main arm64 libtiff6 arm64 4.5.1+git230720-4ubuntu4 [193 kB] 238s Get:56 http://ftpmaster.internal/ubuntu plucky/main arm64 libxft2 arm64 2.3.6-1build1 [44.1 kB] 238s Get:57 http://ftpmaster.internal/ubuntu plucky/main arm64 libxss1 arm64 1:1.2.3-1build3 [7244 B] 238s Get:58 http://ftpmaster.internal/ubuntu plucky/main arm64 libtk8.6 arm64 8.6.16-1 [776 kB] 238s Get:59 http://ftpmaster.internal/ubuntu plucky/main arm64 libxt6t64 arm64 1:1.2.1-1.2build1 [168 kB] 239s Get:60 http://ftpmaster.internal/ubuntu plucky/main arm64 zip arm64 3.0-14ubuntu2 [173 kB] 239s Get:61 http://ftpmaster.internal/ubuntu plucky/main arm64 unzip arm64 6.0-28ubuntu6 [178 kB] 239s Get:62 http://ftpmaster.internal/ubuntu plucky/main arm64 xdg-utils all 1.2.1-2ubuntu1 [66.0 kB] 239s Get:63 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-base-core arm64 4.4.3-1 [28.4 MB] 262s Get:64 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-littler arm64 0.3.20-2 [96.1 kB] 262s Get:65 http://ftpmaster.internal/ubuntu plucky/universe arm64 littler all 0.3.20-2 [2554 B] 262s Get:66 http://ftpmaster.internal/ubuntu plucky/universe arm64 node-bootstrap-sass all 3.4.3-2 [187 kB] 262s Get:67 http://ftpmaster.internal/ubuntu plucky/universe arm64 node-html5shiv all 3.7.3+dfsg-5 [13.5 kB] 262s Get:68 http://ftpmaster.internal/ubuntu plucky/universe arm64 node-normalize.css all 8.0.1-5 [10.8 kB] 262s Get:69 http://ftpmaster.internal/ubuntu plucky/universe arm64 pandoc-data all 3.1.11.1-3build1 [78.8 kB] 262s Get:70 http://ftpmaster.internal/ubuntu plucky/universe arm64 pandoc arm64 3.1.11.1+ds-2 [28.1 MB] 290s Get:71 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-base64enc arm64 0.1-3-3 [27.4 kB] 290s Get:72 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-brio arm64 1.1.5-1 [39.1 kB] 290s Get:73 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rlang arm64 1.1.5-1 [1707 kB] 292s Get:74 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-fastmap arm64 1.2.0-1 [70.6 kB] 292s Get:75 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-cachem arm64 1.1.0-1 [74.1 kB] 292s Get:76 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-digest arm64 0.6.37-1 [200 kB] 292s Get:77 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-htmltools arm64 0.5.8.1-1 [373 kB] 292s Get:78 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-jquerylib all 0.1.4+dfsg-4 [13.5 kB] 293s Get:79 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-jsonlite arm64 1.9.1+dfsg-1 [445 kB] 293s Get:80 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-cli arm64 3.6.4-1 [1374 kB] 295s Get:81 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-glue arm64 1.8.0-1 [163 kB] 295s Get:82 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-lifecycle all 1.0.4+dfsg-1 [110 kB] 295s Get:83 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-memoise all 2.0.1-1 [53.9 kB] 295s Get:84 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-mime arm64 0.12-2 [35.8 kB] 296s Get:85 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-fs arm64 1.6.5+dfsg-1 [244 kB] 296s Get:86 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-r6 all 2.6.1-1 [101 kB] 296s Get:87 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rappdirs arm64 0.3.3-1 [47.5 kB] 297s Get:88 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-sass arm64 0.4.9+dfsg-1 [957 kB] 298s Get:89 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-bslib all 0.8.0+dfsg-1 [4294 kB] 303s Get:90 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-ps arm64 1.9.0-1 [407 kB] 303s Get:91 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-processx arm64 3.8.6-1 [363 kB] 304s Get:92 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-callr all 3.7.6-1 [458 kB] 304s Get:93 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-codetools all 0.2-20-1 [90.5 kB] 305s Get:94 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-colorspace arm64 2.1-1+dfsg-1 [1563 kB] 307s Get:95 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-commonmark arm64 1.9.2-2 [129 kB] 307s Get:96 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-crayon all 1.5.3-1 [165 kB] 307s Get:97 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-desc all 1.4.3-1 [359 kB] 308s Get:98 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-diffobj arm64 0.3.5-1 [1116 kB] 309s Get:99 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-gtable all 0.3.6+dfsg-1 [199 kB] 309s Get:100 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-isoband arm64 0.2.7-1 [1481 kB] 311s Get:101 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-mass arm64 7.3-64-1 [1110 kB] 312s Get:102 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-lattice arm64 0.22-6-1 [1363 kB] 314s Get:103 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-nlme arm64 3.1.167-1 [2311 kB] 316s Get:104 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-matrix arm64 1.7-3-1 [4045 kB] 321s Get:105 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-mgcv arm64 1.9-1-1 [3248 kB] 324s Get:106 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-farver arm64 2.1.2-1 [1344 kB] 326s Get:107 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-labeling all 0.4.3-1 [62.1 kB] 326s Get:108 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-munsell all 0.5.1-1 [213 kB] 327s Get:109 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rcolorbrewer all 1.1-3-1build1 [55.4 kB] 327s Get:110 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-viridislite all 0.4.2-2 [1088 kB] 328s Get:111 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-scales all 1.3.0-1 [603 kB] 329s Get:112 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-fansi arm64 1.0.5-1 [616 kB] 330s Get:113 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-magrittr arm64 2.0.3-1 [154 kB] 330s Get:114 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-utf8 arm64 1.2.4-1 [140 kB] 330s Get:115 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-vctrs arm64 0.6.5-1 [1327 kB] 332s Get:116 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-pillar all 1.10.1+dfsg-1 [453 kB] 332s Get:117 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-pkgconfig all 2.0.3-2build1 [19.7 kB] 332s Get:118 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-tibble arm64 3.2.1+dfsg-3 [420 kB] 333s Get:119 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-withr all 3.0.2+dfsg-1 [214 kB] 333s Get:120 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-ggplot2 all 3.5.1+dfsg-1 [3940 kB] 338s Get:121 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-mvtnorm arm64 1.3-3-1 [921 kB] 339s Get:122 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-dosefinding arm64 1.3-1-1 [973 kB] 340s Get:123 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-evaluate all 1.0.3-1 [114 kB] 340s Get:124 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-fontawesome all 0.5.3-1 [1331 kB] 342s Get:125 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-xfun arm64 0.51+dfsg-1 [573 kB] 343s Get:126 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-highr all 0.11+dfsg-1 [38.5 kB] 343s Get:127 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-pkgkitten all 0.2.4-1 [27.2 kB] 343s Get:128 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rcpp arm64 1.0.14-1 [1978 kB] 346s Get:129 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-later arm64 1.4.1+dfsg-1 [141 kB] 346s Get:130 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-promises arm64 1.3.2+dfsg-1 [290 kB] 346s Get:131 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-httpuv arm64 1.6.15+dfsg-1 [489 kB] 347s Get:132 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-yaml arm64 2.3.10-1 [108 kB] 347s Get:133 http://ftpmaster.internal/ubuntu plucky/main arm64 libjs-mathjax all 2.7.9+dfsg-1 [5665 kB] 353s Get:134 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-knitr all 1.49+dfsg-1 [859 kB] 355s Get:135 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-survival arm64 3.8-3-1 [8213 kB] 363s Get:136 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-th.data all 1.1-3-1 [8723 kB] 373s Get:137 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-zoo arm64 1.8-13-1 [996 kB] 374s Get:138 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-sandwich all 3.1-1-1 [1483 kB] 376s Get:139 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-multcomp all 1.4-28-1 [700 kB] 376s Get:140 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-numderiv all 2016.8-1.1-3 [115 kB] 377s Get:141 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-pkgbuild all 1.4.6-1 [213 kB] 377s Get:142 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rprojroot all 2.0.4-2 [125 kB] 377s Get:143 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-pkgload all 1.4.0-1 [247 kB] 378s Get:144 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-praise all 1.0.0-4build1 [20.3 kB] 378s Get:145 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-quadprog arm64 1.5-8-1build1 [29.8 kB] 378s Get:146 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-tinytex all 0.56-1 [148 kB] 378s Get:147 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-modernizr all 3.13.0-0.1 [101 kB] 378s Get:148 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-xtable all 1:1.8-4-2 [689 kB] 379s Get:149 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-sourcetools arm64 0.1.7-1-1 [47.2 kB] 379s Get:150 http://ftpmaster.internal/ubuntu plucky/universe arm64 libjs-twitter-bootstrap-datepicker all 1.3.1+dfsg1-4.1 [28.5 kB] 379s Get:151 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-shiny all 1.10.0+dfsg-2 [3124 kB] 383s Get:152 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rmarkdown all 2.29+dfsg-1 [1501 kB] 384s Get:153 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-truncnorm arm64 1.0-9-2 [24.9 kB] 385s Get:154 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-rsolnp all 1.16+dfsg-4build1 [249 kB] 385s Get:155 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-waldo all 0.6.1-2 [150 kB] 385s Get:156 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-cran-testthat arm64 3.2.3-1 [1644 kB] 388s Preconfiguring packages ... 388s Fetched 153 MB in 2min 40s (961 kB/s) 388s Selecting previously unselected package fonts-dejavu-mono. 389s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 81647 files and directories currently installed.) 389s Preparing to unpack .../000-fonts-dejavu-mono_2.37-8_all.deb ... 389s Unpacking fonts-dejavu-mono (2.37-8) ... 389s Selecting previously unselected package fonts-dejavu-core. 389s Preparing to unpack .../001-fonts-dejavu-core_2.37-8_all.deb ... 389s Unpacking fonts-dejavu-core (2.37-8) ... 389s Selecting previously unselected package fontconfig-config. 389s Preparing to unpack .../002-fontconfig-config_2.15.0-2ubuntu1_arm64.deb ... 389s Unpacking fontconfig-config (2.15.0-2ubuntu1) ... 389s Selecting previously unselected package libfontconfig1:arm64. 389s Preparing to unpack .../003-libfontconfig1_2.15.0-2ubuntu1_arm64.deb ... 389s Unpacking libfontconfig1:arm64 (2.15.0-2ubuntu1) ... 389s Selecting previously unselected package fontconfig. 389s Preparing to unpack .../004-fontconfig_2.15.0-2ubuntu1_arm64.deb ... 389s Unpacking fontconfig (2.15.0-2ubuntu1) ... 389s Selecting previously unselected package fonts-font-awesome. 389s Preparing to unpack .../005-fonts-font-awesome_5.0.10+really4.7.0~dfsg-4.1_all.deb ... 389s Unpacking fonts-font-awesome (5.0.10+really4.7.0~dfsg-4.1) ... 389s Selecting previously unselected package fonts-glyphicons-halflings. 389s Preparing to unpack .../006-fonts-glyphicons-halflings_1.009~3.4.1+dfsg-3_all.deb ... 389s Unpacking fonts-glyphicons-halflings (1.009~3.4.1+dfsg-3) ... 389s Selecting previously unselected package fonts-mathjax. 389s Preparing to unpack .../007-fonts-mathjax_2.7.9+dfsg-1_all.deb ... 389s Unpacking fonts-mathjax (2.7.9+dfsg-1) ... 390s Selecting previously unselected package javascript-common. 390s Preparing to unpack .../008-javascript-common_12_all.deb ... 390s Unpacking javascript-common (12) ... 390s Selecting previously unselected package libblas3:arm64. 390s Preparing to unpack .../009-libblas3_3.12.1-2_arm64.deb ... 390s Unpacking libblas3:arm64 (3.12.1-2) ... 390s Selecting previously unselected package libpixman-1-0:arm64. 390s Preparing to unpack .../010-libpixman-1-0_0.44.0-3_arm64.deb ... 390s Unpacking libpixman-1-0:arm64 (0.44.0-3) ... 390s Selecting previously unselected package libxcb-render0:arm64. 390s Preparing to unpack .../011-libxcb-render0_1.17.0-2_arm64.deb ... 390s Unpacking libxcb-render0:arm64 (1.17.0-2) ... 390s Selecting previously unselected package libxcb-shm0:arm64. 390s Preparing to unpack .../012-libxcb-shm0_1.17.0-2_arm64.deb ... 390s Unpacking libxcb-shm0:arm64 (1.17.0-2) ... 390s Selecting previously unselected package libxrender1:arm64. 390s Preparing to unpack .../013-libxrender1_1%3a0.9.10-1.1build1_arm64.deb ... 390s Unpacking libxrender1:arm64 (1:0.9.10-1.1build1) ... 390s Selecting previously unselected package libcairo2:arm64. 390s Preparing to unpack .../014-libcairo2_1.18.2-2_arm64.deb ... 390s Unpacking libcairo2:arm64 (1.18.2-2) ... 390s Selecting previously unselected package libdatrie1:arm64. 390s Preparing to unpack .../015-libdatrie1_0.2.13-3build1_arm64.deb ... 390s Unpacking libdatrie1:arm64 (0.2.13-3build1) ... 390s Selecting previously unselected package libdeflate0:arm64. 390s Preparing to unpack .../016-libdeflate0_1.23-1_arm64.deb ... 390s Unpacking libdeflate0:arm64 (1.23-1) ... 390s Selecting previously unselected package libgfortran5:arm64. 390s Preparing to unpack .../017-libgfortran5_15-20250222-0ubuntu1_arm64.deb ... 390s Unpacking libgfortran5:arm64 (15-20250222-0ubuntu1) ... 390s Selecting previously unselected package libgomp1:arm64. 390s Preparing to unpack .../018-libgomp1_15-20250222-0ubuntu1_arm64.deb ... 390s Unpacking libgomp1:arm64 (15-20250222-0ubuntu1) ... 390s Selecting previously unselected package libgraphite2-3:arm64. 390s Preparing to unpack .../019-libgraphite2-3_1.3.14-2ubuntu1_arm64.deb ... 390s Unpacking libgraphite2-3:arm64 (1.3.14-2ubuntu1) ... 390s Selecting previously unselected package libharfbuzz0b:arm64. 390s Preparing to unpack .../020-libharfbuzz0b_10.2.0-1_arm64.deb ... 390s Unpacking libharfbuzz0b:arm64 (10.2.0-1) ... 390s Selecting previously unselected package x11-common. 390s Preparing to unpack .../021-x11-common_1%3a7.7+23ubuntu3_all.deb ... 390s Unpacking x11-common (1:7.7+23ubuntu3) ... 390s Selecting previously unselected package libice6:arm64. 390s Preparing to unpack .../022-libice6_2%3a1.1.1-1_arm64.deb ... 390s Unpacking libice6:arm64 (2:1.1.1-1) ... 390s Selecting previously unselected package libjpeg-turbo8:arm64. 391s Preparing to unpack .../023-libjpeg-turbo8_2.1.5-3ubuntu2_arm64.deb ... 391s Unpacking libjpeg-turbo8:arm64 (2.1.5-3ubuntu2) ... 391s Selecting previously unselected package libjpeg8:arm64. 391s Preparing to unpack .../024-libjpeg8_8c-2ubuntu11_arm64.deb ... 391s Unpacking libjpeg8:arm64 (8c-2ubuntu11) ... 391s Selecting previously unselected package libjs-bootstrap. 391s Preparing to unpack .../025-libjs-bootstrap_3.4.1+dfsg-3_all.deb ... 391s Unpacking libjs-bootstrap (3.4.1+dfsg-3) ... 391s Selecting previously unselected package libjs-popper.js. 391s Preparing to unpack .../026-libjs-popper.js_1.16.1+ds-6_all.deb ... 391s Unpacking libjs-popper.js (1.16.1+ds-6) ... 391s Selecting previously unselected package libjs-bootstrap4. 391s Preparing to unpack .../027-libjs-bootstrap4_4.6.1+dfsg1-4_all.deb ... 391s Unpacking libjs-bootstrap4 (4.6.1+dfsg1-4) ... 391s Selecting previously unselected package libjs-d3. 391s Preparing to unpack .../028-libjs-d3_3.5.17-4_all.deb ... 391s Unpacking libjs-d3 (3.5.17-4) ... 391s Selecting previously unselected package libjs-es5-shim. 391s Preparing to unpack .../029-libjs-es5-shim_4.6.7-2_all.deb ... 391s Unpacking libjs-es5-shim (4.6.7-2) ... 391s Selecting previously unselected package libjs-highlight.js. 391s Preparing to unpack .../030-libjs-highlight.js_9.18.5+dfsg1-2_all.deb ... 391s Unpacking libjs-highlight.js (9.18.5+dfsg1-2) ... 391s Selecting previously unselected package libjs-jquery. 391s Preparing to unpack .../031-libjs-jquery_3.6.1+dfsg+~3.5.14-1_all.deb ... 391s Unpacking libjs-jquery (3.6.1+dfsg+~3.5.14-1) ... 391s Selecting previously unselected package libjs-jquery-datatables. 391s Preparing to unpack .../032-libjs-jquery-datatables_1.11.5+dfsg-2_all.deb ... 391s Unpacking libjs-jquery-datatables (1.11.5+dfsg-2) ... 391s Selecting previously unselected package libjs-sifter.js. 391s Preparing to unpack .../033-libjs-sifter.js_0.6.0+dfsg-3_all.deb ... 391s Unpacking libjs-sifter.js (0.6.0+dfsg-3) ... 391s Selecting previously unselected package libjs-microplugin.js. 391s Preparing to unpack .../034-libjs-microplugin.js_0.0.3+dfsg-1.1_all.deb ... 391s Unpacking libjs-microplugin.js (0.0.3+dfsg-1.1) ... 391s Selecting previously unselected package libjs-jquery-selectize.js. 391s Preparing to unpack .../035-libjs-jquery-selectize.js_0.12.6+dfsg-1.1_all.deb ... 391s Unpacking libjs-jquery-selectize.js (0.12.6+dfsg-1.1) ... 391s Selecting previously unselected package libjs-jquery-ui. 391s Preparing to unpack .../036-libjs-jquery-ui_1.13.2+dfsg-1_all.deb ... 391s Unpacking libjs-jquery-ui (1.13.2+dfsg-1) ... 391s Selecting previously unselected package libjs-json. 391s Preparing to unpack .../037-libjs-json_0~20221030+~1.0.8-1_all.deb ... 391s Unpacking libjs-json (0~20221030+~1.0.8-1) ... 391s Selecting previously unselected package libjs-prettify. 391s Preparing to unpack .../038-libjs-prettify_2015.12.04+dfsg-1.1_all.deb ... 391s Unpacking libjs-prettify (2015.12.04+dfsg-1.1) ... 391s Selecting previously unselected package liblapack3:arm64. 391s Preparing to unpack .../039-liblapack3_3.12.1-2_arm64.deb ... 391s Unpacking liblapack3:arm64 (3.12.1-2) ... 392s Selecting previously unselected package liblerc4:arm64. 392s Preparing to unpack .../040-liblerc4_4.0.0+ds-5ubuntu1_arm64.deb ... 392s Unpacking liblerc4:arm64 (4.0.0+ds-5ubuntu1) ... 392s Selecting previously unselected package liblua5.4-0:arm64. 392s Preparing to unpack .../041-liblua5.4-0_5.4.7-1_arm64.deb ... 392s Unpacking liblua5.4-0:arm64 (5.4.7-1) ... 392s Selecting previously unselected package libthai-data. 392s Preparing to unpack .../042-libthai-data_0.1.29-2build1_all.deb ... 392s Unpacking libthai-data (0.1.29-2build1) ... 392s Selecting previously unselected package libthai0:arm64. 392s Preparing to unpack .../043-libthai0_0.1.29-2build1_arm64.deb ... 392s Unpacking libthai0:arm64 (0.1.29-2build1) ... 392s Selecting previously unselected package libpango-1.0-0:arm64. 392s Preparing to unpack .../044-libpango-1.0-0_1.56.2-1_arm64.deb ... 392s Unpacking libpango-1.0-0:arm64 (1.56.2-1) ... 392s Selecting previously unselected package libpangoft2-1.0-0:arm64. 392s Preparing to unpack .../045-libpangoft2-1.0-0_1.56.2-1_arm64.deb ... 392s Unpacking libpangoft2-1.0-0:arm64 (1.56.2-1) ... 392s Selecting previously unselected package libpangocairo-1.0-0:arm64. 392s Preparing to unpack .../046-libpangocairo-1.0-0_1.56.2-1_arm64.deb ... 392s Unpacking libpangocairo-1.0-0:arm64 (1.56.2-1) ... 392s Selecting previously unselected package libpaper2:arm64. 392s Preparing to unpack .../047-libpaper2_2.2.5-0.3_arm64.deb ... 392s Unpacking libpaper2:arm64 (2.2.5-0.3) ... 392s Selecting previously unselected package libpaper-utils. 392s Preparing to unpack .../048-libpaper-utils_2.2.5-0.3_arm64.deb ... 392s Unpacking libpaper-utils (2.2.5-0.3) ... 392s Selecting previously unselected package libsharpyuv0:arm64. 392s Preparing to unpack .../049-libsharpyuv0_1.5.0-0.1_arm64.deb ... 392s Unpacking libsharpyuv0:arm64 (1.5.0-0.1) ... 392s Selecting previously unselected package libsm6:arm64. 392s Preparing to unpack .../050-libsm6_2%3a1.2.4-1_arm64.deb ... 392s Unpacking libsm6:arm64 (2:1.2.4-1) ... 392s Selecting previously unselected package libtcl8.6:arm64. 392s Preparing to unpack .../051-libtcl8.6_8.6.16+dfsg-1_arm64.deb ... 392s Unpacking libtcl8.6:arm64 (8.6.16+dfsg-1) ... 392s Selecting previously unselected package libjbig0:arm64. 392s Preparing to unpack .../052-libjbig0_2.1-6.1ubuntu2_arm64.deb ... 392s Unpacking libjbig0:arm64 (2.1-6.1ubuntu2) ... 392s Selecting previously unselected package libwebp7:arm64. 392s Preparing to unpack .../053-libwebp7_1.5.0-0.1_arm64.deb ... 392s Unpacking libwebp7:arm64 (1.5.0-0.1) ... 392s Selecting previously unselected package libtiff6:arm64. 392s Preparing to unpack .../054-libtiff6_4.5.1+git230720-4ubuntu4_arm64.deb ... 392s Unpacking libtiff6:arm64 (4.5.1+git230720-4ubuntu4) ... 392s Selecting previously unselected package libxft2:arm64. 392s Preparing to unpack .../055-libxft2_2.3.6-1build1_arm64.deb ... 392s Unpacking libxft2:arm64 (2.3.6-1build1) ... 393s Selecting previously unselected package libxss1:arm64. 393s Preparing to unpack .../056-libxss1_1%3a1.2.3-1build3_arm64.deb ... 393s Unpacking libxss1:arm64 (1:1.2.3-1build3) ... 393s Selecting previously unselected package libtk8.6:arm64. 393s Preparing to unpack .../057-libtk8.6_8.6.16-1_arm64.deb ... 393s Unpacking libtk8.6:arm64 (8.6.16-1) ... 393s Selecting previously unselected package libxt6t64:arm64. 393s Preparing to unpack .../058-libxt6t64_1%3a1.2.1-1.2build1_arm64.deb ... 393s Unpacking libxt6t64:arm64 (1:1.2.1-1.2build1) ... 393s Selecting previously unselected package zip. 393s Preparing to unpack .../059-zip_3.0-14ubuntu2_arm64.deb ... 393s Unpacking zip (3.0-14ubuntu2) ... 393s Selecting previously unselected package unzip. 393s Preparing to unpack .../060-unzip_6.0-28ubuntu6_arm64.deb ... 393s Unpacking unzip (6.0-28ubuntu6) ... 393s Selecting previously unselected package xdg-utils. 393s Preparing to unpack .../061-xdg-utils_1.2.1-2ubuntu1_all.deb ... 393s Unpacking xdg-utils (1.2.1-2ubuntu1) ... 393s Selecting previously unselected package r-base-core. 393s Preparing to unpack .../062-r-base-core_4.4.3-1_arm64.deb ... 393s Unpacking r-base-core (4.4.3-1) ... 393s Selecting previously unselected package r-cran-littler. 394s Preparing to unpack .../063-r-cran-littler_0.3.20-2_arm64.deb ... 394s Unpacking r-cran-littler (0.3.20-2) ... 394s Selecting previously unselected package littler. 394s Preparing to unpack .../064-littler_0.3.20-2_all.deb ... 394s Unpacking littler (0.3.20-2) ... 394s Selecting previously unselected package node-bootstrap-sass. 394s Preparing to unpack .../065-node-bootstrap-sass_3.4.3-2_all.deb ... 394s Unpacking node-bootstrap-sass (3.4.3-2) ... 394s Selecting previously unselected package node-html5shiv. 394s Preparing to unpack .../066-node-html5shiv_3.7.3+dfsg-5_all.deb ... 394s Unpacking node-html5shiv (3.7.3+dfsg-5) ... 394s Selecting previously unselected package node-normalize.css. 394s Preparing to unpack .../067-node-normalize.css_8.0.1-5_all.deb ... 394s Unpacking node-normalize.css (8.0.1-5) ... 394s Selecting previously unselected package pandoc-data. 394s Preparing to unpack .../068-pandoc-data_3.1.11.1-3build1_all.deb ... 394s Unpacking pandoc-data (3.1.11.1-3build1) ... 394s Selecting previously unselected package pandoc. 394s Preparing to unpack .../069-pandoc_3.1.11.1+ds-2_arm64.deb ... 394s Unpacking pandoc (3.1.11.1+ds-2) ... 395s Selecting previously unselected package r-cran-base64enc. 395s Preparing to unpack .../070-r-cran-base64enc_0.1-3-3_arm64.deb ... 395s Unpacking r-cran-base64enc (0.1-3-3) ... 395s Selecting previously unselected package r-cran-brio. 395s Preparing to unpack .../071-r-cran-brio_1.1.5-1_arm64.deb ... 395s Unpacking r-cran-brio (1.1.5-1) ... 395s Selecting previously unselected package r-cran-rlang. 396s Preparing to unpack .../072-r-cran-rlang_1.1.5-1_arm64.deb ... 396s Unpacking r-cran-rlang (1.1.5-1) ... 396s Selecting previously unselected package r-cran-fastmap. 396s Preparing to unpack .../073-r-cran-fastmap_1.2.0-1_arm64.deb ... 396s Unpacking r-cran-fastmap (1.2.0-1) ... 396s Selecting previously unselected package r-cran-cachem. 396s Preparing to unpack .../074-r-cran-cachem_1.1.0-1_arm64.deb ... 396s Unpacking r-cran-cachem (1.1.0-1) ... 396s Selecting previously unselected package r-cran-digest. 396s Preparing to unpack .../075-r-cran-digest_0.6.37-1_arm64.deb ... 396s Unpacking r-cran-digest (0.6.37-1) ... 396s Selecting previously unselected package r-cran-htmltools. 396s Preparing to unpack .../076-r-cran-htmltools_0.5.8.1-1_arm64.deb ... 396s Unpacking r-cran-htmltools (0.5.8.1-1) ... 396s Selecting previously unselected package r-cran-jquerylib. 396s Preparing to unpack .../077-r-cran-jquerylib_0.1.4+dfsg-4_all.deb ... 396s Unpacking r-cran-jquerylib (0.1.4+dfsg-4) ... 396s Selecting previously unselected package r-cran-jsonlite. 396s Preparing to unpack .../078-r-cran-jsonlite_1.9.1+dfsg-1_arm64.deb ... 396s Unpacking r-cran-jsonlite (1.9.1+dfsg-1) ... 396s Selecting previously unselected package r-cran-cli. 396s Preparing to unpack .../079-r-cran-cli_3.6.4-1_arm64.deb ... 396s Unpacking r-cran-cli (3.6.4-1) ... 396s Selecting previously unselected package r-cran-glue. 396s Preparing to unpack .../080-r-cran-glue_1.8.0-1_arm64.deb ... 396s Unpacking r-cran-glue (1.8.0-1) ... 396s Selecting previously unselected package r-cran-lifecycle. 396s Preparing to unpack .../081-r-cran-lifecycle_1.0.4+dfsg-1_all.deb ... 396s Unpacking r-cran-lifecycle (1.0.4+dfsg-1) ... 396s Selecting previously unselected package r-cran-memoise. 396s Preparing to unpack .../082-r-cran-memoise_2.0.1-1_all.deb ... 396s Unpacking r-cran-memoise (2.0.1-1) ... 396s Selecting previously unselected package r-cran-mime. 396s Preparing to unpack .../083-r-cran-mime_0.12-2_arm64.deb ... 396s Unpacking r-cran-mime (0.12-2) ... 396s Selecting previously unselected package r-cran-fs. 396s Preparing to unpack .../084-r-cran-fs_1.6.5+dfsg-1_arm64.deb ... 396s Unpacking r-cran-fs (1.6.5+dfsg-1) ... 396s Selecting previously unselected package r-cran-r6. 396s Preparing to unpack .../085-r-cran-r6_2.6.1-1_all.deb ... 396s Unpacking r-cran-r6 (2.6.1-1) ... 396s Selecting previously unselected package r-cran-rappdirs. 396s Preparing to unpack .../086-r-cran-rappdirs_0.3.3-1_arm64.deb ... 396s Unpacking r-cran-rappdirs (0.3.3-1) ... 397s Selecting previously unselected package r-cran-sass. 397s Preparing to unpack .../087-r-cran-sass_0.4.9+dfsg-1_arm64.deb ... 397s Unpacking r-cran-sass (0.4.9+dfsg-1) ... 397s Selecting previously unselected package r-cran-bslib. 397s Preparing to unpack .../088-r-cran-bslib_0.8.0+dfsg-1_all.deb ... 397s Unpacking r-cran-bslib (0.8.0+dfsg-1) ... 397s Selecting previously unselected package r-cran-ps. 397s Preparing to unpack .../089-r-cran-ps_1.9.0-1_arm64.deb ... 397s Unpacking r-cran-ps (1.9.0-1) ... 397s Selecting previously unselected package r-cran-processx. 397s Preparing to unpack .../090-r-cran-processx_3.8.6-1_arm64.deb ... 397s Unpacking r-cran-processx (3.8.6-1) ... 397s Selecting previously unselected package r-cran-callr. 397s Preparing to unpack .../091-r-cran-callr_3.7.6-1_all.deb ... 397s Unpacking r-cran-callr (3.7.6-1) ... 397s Selecting previously unselected package r-cran-codetools. 397s Preparing to unpack .../092-r-cran-codetools_0.2-20-1_all.deb ... 397s Unpacking r-cran-codetools (0.2-20-1) ... 397s Selecting previously unselected package r-cran-colorspace. 397s Preparing to unpack .../093-r-cran-colorspace_2.1-1+dfsg-1_arm64.deb ... 397s Unpacking r-cran-colorspace (2.1-1+dfsg-1) ... 397s Selecting previously unselected package r-cran-commonmark. 397s Preparing to unpack .../094-r-cran-commonmark_1.9.2-2_arm64.deb ... 397s Unpacking r-cran-commonmark (1.9.2-2) ... 397s Selecting previously unselected package r-cran-crayon. 397s Preparing to unpack .../095-r-cran-crayon_1.5.3-1_all.deb ... 397s Unpacking r-cran-crayon (1.5.3-1) ... 397s Selecting previously unselected package r-cran-desc. 397s Preparing to unpack .../096-r-cran-desc_1.4.3-1_all.deb ... 397s Unpacking r-cran-desc (1.4.3-1) ... 397s Selecting previously unselected package r-cran-diffobj. 397s Preparing to unpack .../097-r-cran-diffobj_0.3.5-1_arm64.deb ... 397s Unpacking r-cran-diffobj (0.3.5-1) ... 397s Selecting previously unselected package r-cran-gtable. 397s Preparing to unpack .../098-r-cran-gtable_0.3.6+dfsg-1_all.deb ... 397s Unpacking r-cran-gtable (0.3.6+dfsg-1) ... 397s Selecting previously unselected package r-cran-isoband. 398s Preparing to unpack .../099-r-cran-isoband_0.2.7-1_arm64.deb ... 398s Unpacking r-cran-isoband (0.2.7-1) ... 398s Selecting previously unselected package r-cran-mass. 398s Preparing to unpack .../100-r-cran-mass_7.3-64-1_arm64.deb ... 398s Unpacking r-cran-mass (7.3-64-1) ... 398s Selecting previously unselected package r-cran-lattice. 398s Preparing to unpack .../101-r-cran-lattice_0.22-6-1_arm64.deb ... 398s Unpacking r-cran-lattice (0.22-6-1) ... 398s Selecting previously unselected package r-cran-nlme. 398s Preparing to unpack .../102-r-cran-nlme_3.1.167-1_arm64.deb ... 398s Unpacking r-cran-nlme (3.1.167-1) ... 398s Selecting previously unselected package r-cran-matrix. 398s Preparing to unpack .../103-r-cran-matrix_1.7-3-1_arm64.deb ... 398s Unpacking r-cran-matrix (1.7-3-1) ... 398s Selecting previously unselected package r-cran-mgcv. 398s Preparing to unpack .../104-r-cran-mgcv_1.9-1-1_arm64.deb ... 398s Unpacking r-cran-mgcv (1.9-1-1) ... 398s Selecting previously unselected package r-cran-farver. 398s Preparing to unpack .../105-r-cran-farver_2.1.2-1_arm64.deb ... 398s Unpacking r-cran-farver (2.1.2-1) ... 398s Selecting previously unselected package r-cran-labeling. 398s Preparing to unpack .../106-r-cran-labeling_0.4.3-1_all.deb ... 398s Unpacking r-cran-labeling (0.4.3-1) ... 398s Selecting previously unselected package r-cran-munsell. 398s Preparing to unpack .../107-r-cran-munsell_0.5.1-1_all.deb ... 398s Unpacking r-cran-munsell (0.5.1-1) ... 398s Selecting previously unselected package r-cran-rcolorbrewer. 398s Preparing to unpack .../108-r-cran-rcolorbrewer_1.1-3-1build1_all.deb ... 398s Unpacking r-cran-rcolorbrewer (1.1-3-1build1) ... 398s Selecting previously unselected package r-cran-viridislite. 398s Preparing to unpack .../109-r-cran-viridislite_0.4.2-2_all.deb ... 398s Unpacking r-cran-viridislite (0.4.2-2) ... 398s Selecting previously unselected package r-cran-scales. 398s Preparing to unpack .../110-r-cran-scales_1.3.0-1_all.deb ... 398s Unpacking r-cran-scales (1.3.0-1) ... 398s Selecting previously unselected package r-cran-fansi. 398s Preparing to unpack .../111-r-cran-fansi_1.0.5-1_arm64.deb ... 398s Unpacking r-cran-fansi (1.0.5-1) ... 399s Selecting previously unselected package r-cran-magrittr. 399s Preparing to unpack .../112-r-cran-magrittr_2.0.3-1_arm64.deb ... 399s Unpacking r-cran-magrittr (2.0.3-1) ... 399s Selecting previously unselected package r-cran-utf8. 399s Preparing to unpack .../113-r-cran-utf8_1.2.4-1_arm64.deb ... 399s Unpacking r-cran-utf8 (1.2.4-1) ... 399s Selecting previously unselected package r-cran-vctrs. 399s Preparing to unpack .../114-r-cran-vctrs_0.6.5-1_arm64.deb ... 399s Unpacking r-cran-vctrs (0.6.5-1) ... 399s Selecting previously unselected package r-cran-pillar. 399s Preparing to unpack .../115-r-cran-pillar_1.10.1+dfsg-1_all.deb ... 399s Unpacking r-cran-pillar (1.10.1+dfsg-1) ... 399s Selecting previously unselected package r-cran-pkgconfig. 399s Preparing to unpack .../116-r-cran-pkgconfig_2.0.3-2build1_all.deb ... 399s Unpacking r-cran-pkgconfig (2.0.3-2build1) ... 399s Selecting previously unselected package r-cran-tibble. 399s Preparing to unpack .../117-r-cran-tibble_3.2.1+dfsg-3_arm64.deb ... 399s Unpacking r-cran-tibble (3.2.1+dfsg-3) ... 399s Selecting previously unselected package r-cran-withr. 399s Preparing to unpack .../118-r-cran-withr_3.0.2+dfsg-1_all.deb ... 399s Unpacking r-cran-withr (3.0.2+dfsg-1) ... 399s Selecting previously unselected package r-cran-ggplot2. 399s Preparing to unpack .../119-r-cran-ggplot2_3.5.1+dfsg-1_all.deb ... 399s Unpacking r-cran-ggplot2 (3.5.1+dfsg-1) ... 399s Selecting previously unselected package r-cran-mvtnorm. 399s Preparing to unpack .../120-r-cran-mvtnorm_1.3-3-1_arm64.deb ... 399s Unpacking r-cran-mvtnorm (1.3-3-1) ... 399s Selecting previously unselected package r-cran-dosefinding. 399s Preparing to unpack .../121-r-cran-dosefinding_1.3-1-1_arm64.deb ... 399s Unpacking r-cran-dosefinding (1.3-1-1) ... 399s Selecting previously unselected package r-cran-evaluate. 399s Preparing to unpack .../122-r-cran-evaluate_1.0.3-1_all.deb ... 399s Unpacking r-cran-evaluate (1.0.3-1) ... 399s Selecting previously unselected package r-cran-fontawesome. 399s Preparing to unpack .../123-r-cran-fontawesome_0.5.3-1_all.deb ... 399s Unpacking r-cran-fontawesome (0.5.3-1) ... 399s Selecting previously unselected package r-cran-xfun. 400s Preparing to unpack .../124-r-cran-xfun_0.51+dfsg-1_arm64.deb ... 400s Unpacking r-cran-xfun (0.51+dfsg-1) ... 400s Selecting previously unselected package r-cran-highr. 400s Preparing to unpack .../125-r-cran-highr_0.11+dfsg-1_all.deb ... 400s Unpacking r-cran-highr (0.11+dfsg-1) ... 400s Selecting previously unselected package r-cran-pkgkitten. 400s Preparing to unpack .../126-r-cran-pkgkitten_0.2.4-1_all.deb ... 400s Unpacking r-cran-pkgkitten (0.2.4-1) ... 400s Selecting previously unselected package r-cran-rcpp. 400s Preparing to unpack .../127-r-cran-rcpp_1.0.14-1_arm64.deb ... 400s Unpacking r-cran-rcpp (1.0.14-1) ... 400s Selecting previously unselected package r-cran-later. 400s Preparing to unpack .../128-r-cran-later_1.4.1+dfsg-1_arm64.deb ... 400s Unpacking r-cran-later 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(0.4.9+dfsg-1) ... 407s Setting up r-cran-vctrs (0.6.5-1) ... 407s Setting up r-cran-pillar (1.10.1+dfsg-1) ... 407s Setting up r-cran-callr (3.7.6-1) ... 407s Setting up r-cran-desc (1.4.3-1) ... 407s Setting up r-cran-munsell (0.5.1-1) ... 407s Setting up r-cran-tibble (3.2.1+dfsg-3) ... 407s Setting up r-cran-sandwich (3.1-1-1) ... 407s Setting up r-cran-fontawesome (0.5.3-1) ... 407s Setting up r-cran-survival (3.8-3-1) ... 407s Setting up r-cran-jquerylib (0.1.4+dfsg-4) ... 407s Setting up r-cran-th.data (1.1-3-1) ... 407s Setting up r-cran-scales (1.3.0-1) ... 407s Setting up r-cran-memoise (2.0.1-1) ... 407s Setting up r-cran-promises (1.3.2+dfsg-1) ... 407s Setting up r-cran-multcomp (1.4-28-1) ... 407s Setting up r-cran-pkgbuild (1.4.6-1) ... 407s Setting up r-cran-pkgload (1.4.0-1) ... 407s Setting up r-cran-ggplot2 (3.5.1+dfsg-1) ... 407s Setting up r-cran-httpuv (1.6.15+dfsg-1) ... 407s Setting up r-cran-testthat (3.2.3-1) ... 407s Setting up r-cran-bslib (0.8.0+dfsg-1) ... 407s Setting up r-cran-dosefinding (1.3-1-1) ... 407s Setting up r-cran-shiny (1.10.0+dfsg-2) ... 407s Setting up r-cran-rmarkdown (2.29+dfsg-1) ... 407s Processing triggers for libc-bin (2.41-1ubuntu2) ... 407s Processing triggers for man-db (2.13.0-1) ... 409s Processing triggers for install-info (7.1.1-1) ... 410s autopkgtest [15:30:37]: test run-unit-test: [----------------------- 411s Loading required package: DoseFinding 412s Dose Response Model 412s 412s Model: linear 412s Fit-type: general 412s 412s Coefficients dose-response model 412s delta 412s 0.07484 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 3.472 412s Dose Response Model 412s 412s Model: linear 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 delta 412s 0.33400 0.07484 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 3.472 412s Dose Response Model 412s 412s Model: quadratic 412s Fit-type: general 412s 412s Coefficients dose-response model 412s b1 b2 412s 0.22800 -0.03811 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.9281 412s Dose Response Model 412s 412s Model: quadratic 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 b1 b2 412s 0.24950 0.22800 -0.03811 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.9281 412s Dose Response Model 412s 412s Model: linlog 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 delta 412s 0.47790 0.07728 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.1605 412s Dose Response Model 412s 412s Model: emax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s eMax ed50 412s 0.3771 0.3630 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.09815 412s Dose Response Model 412s 412s Model: emax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax ed50 412s 0.2221 0.3771 0.3630 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.09815 412s Dose Response Model 412s 412s Model: sigEmax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s eMax ed50 h 412s 0.4714 0.4880 0.5000 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.07825 412s Dose Response Model 412s 412s Model: sigEmax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax ed50 h 412s 0.2223 0.4714 0.4880 0.5000 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.07825 412s Dose Response Model 412s 412s Model: exponential 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e1 delta 412s 0.4391 8.0000 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 4.102 412s Dose Response Model 412s 412s Model: exponential 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 e1 delta 412s 0.3510 0.4391 8.0000 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 4.102 412s Dose Response Model 412s 412s Model: logistic 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax ed50 delta 412s -0.1095 0.6665 0.0040 0.4217 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.1951 412s Dose Response Model 412s 412s Model: betaMod 412s Fit-type: general 412s 412s Coefficients dose-response model 412s eMax delta1 delta2 412s 0.3468 0.2216 0.0500 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.0783 412s Dose Response Model 412s 412s Model: betaMod 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax delta1 delta2 412s 0.2222 0.3468 0.2216 0.0500 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.0783 412s Dose Response Model 412s 412s Model: linInt 412s Fit-type: general 412s 412s Coefficients dose-response model 412s d1 d2 d3 d4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0 412s Dose Response Model 412s 412s Model: linInt 412s Fit-type: general 412s 412s Coefficients dose-response model 412s d0 d1 d2 d3 d4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0 412s Dose Response Model 412s 412s Model: emax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s eMax ed50 412s 0.3771 0.3630 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.09815 412s Dose Response Model 412s 412s Model: emax 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax ed50 412s 0.2221 0.3771 0.3630 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.09815 412s Dose Response Model 412s 412s Model: betaMod 412s Fit-type: general 412s 412s Coefficients dose-response model 412s eMax delta1 delta2 412s 0.3468 0.2216 0.0500 412s 412s Fitted to: 412s 1 2 3 4 412s 0.2846 0.2965 0.3502 0.3480 412s 412s Generalized residual sum of squares: 0.0783 412s Dose Response Model 412s 412s Model: betaMod 412s Fit-type: general 412s 412s Coefficients dose-response model 412s e0 eMax delta1 delta2 412s 0.2222 0.3468 0.2216 0.0500 412s 412s Fitted to: 412s 0 1 2 3 4 412s 0.2220 0.5065 0.5185 0.5722 0.5700 412s 412s Generalized residual sum of squares: 0.0783 412s $fit 412s [1] 0.0000000 0.2756421 0.3165257 0.3387105 0.3466573 412s 412s $se.fit 412s [1] 0.0000000 0.1235753 0.1106156 0.1135736 0.1263900 412s 412s $fit 412s [1] 0.2756421 0.3165257 0.3387105 0.3466573 412s 412s $se.fit 412s [1] 0.1235753 0.1106156 0.1135736 0.1263900 412s 412s e0 eMax delta1 delta2 412s e0 0.0118410628 -0.008186899 0.003722514 -0.0008419768 412s eMax -0.0081868987 0.014334651 -0.016984399 -0.0239850493 412s delta1 0.0037225142 -0.016984399 0.475384246 0.3641344057 412s delta2 -0.0008419768 -0.023985049 0.364134406 0.3356088149 412s eMax delta1 delta2 412s eMax 0.01433465 -0.0169844 -0.02398505 412s delta1 -0.01698440 0.4753842 0.36413441 412s delta2 -0.02398505 0.3641344 0.33560881 413s Message: Setting predType to "ls-means" for "type = general" 413s $fit 413s [1] 0.2219856 0.5065390 0.5185323 0.5721580 0.5699850 413s 413s $se.fit 413s [1] 0.1088272 0.1048057 0.1044027 0.1046862 0.1088405 413s 413s Message: Setting predType to "effect-curve" for placebo-adjusted data 413s $fit 413s [1] 0.0000000 0.2845534 0.2965467 0.3501724 0.3479994 413s 413s $se.fit 413s [1] 0.0000000 0.1252903 0.1265494 0.1279290 0.1273279 413s 413s $fit 413s [1] 0.2845534 0.2965467 0.3501724 0.3479994 413s 413s $se.fit 413s [1] 0.1252903 0.1265494 0.1279290 0.1273279 413s 413s d0 d1 d2 d3 d4 413s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 413s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 413s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 413s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 413s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 413s d1 d2 d3 d4 413s d1 0.015697662 0.008221459 0.008223928 0.008215124 413s d2 0.008221459 0.016014746 0.008246506 0.008208911 413s d3 0.008223928 0.008246506 0.016365819 0.008204394 413s d4 0.008215124 0.008208911 0.008204394 0.016212400 413s d0 d1 d2 d3 d4 413s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 413s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 413s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 413s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 413s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 413s gender2 -0.005149393 -0.005062250 -0.004777264 -0.004570087 -0.005308813 413s gender2 413s d0 -0.005149393 413s d1 -0.005062250 413s d2 -0.004777264 413s d3 -0.004570087 413s d4 -0.005308813 413s gender2 0.007312139 413s d0 d1 d2 d3 d4 413s d0 0.00819461 0.000000000 0.000000000 0.000000000 0.0000000 413s d1 0.00000000 0.007459197 0.000000000 0.000000000 0.0000000 413s d2 0.00000000 0.000000000 0.007757564 0.000000000 0.0000000 413s d3 0.00000000 0.000000000 0.000000000 0.008080796 0.0000000 413s d4 0.00000000 0.000000000 0.000000000 0.000000000 0.0079701 413s d1 d2 d3 d4 413s d1 0.015697662 0.008221459 0.008223928 0.008215124 413s d2 0.008221459 0.016014746 0.008246506 0.008208911 413s d3 0.008223928 0.008246506 0.016365819 0.008204394 413s d4 0.008215124 0.008208911 0.008204394 0.016212400 413s $fit 413s [1] 0.2845534 0.2965467 0.3501724 0.3479994 413s 413s $se.fit 413s [1] 0.1252903 0.1265494 0.1279290 0.1273279 413s 413s testgFit.R passed 413s testplanMod.R passed 414s Loading required package: DoseFinding 415s [1] 0.5099184 415s Calculated TD - optimal design: 415s 0 18.75 415s 0.49999 0.50001 415s Calculated TD - optimal design: 415s 0 104.52 415s 0.49993 0.50006 415s [1] 0.4286171 415s Calculated TD - optimal design: 415s 0 101.57 150 415s 0.43958 0.50000 0.06041 415s Calculated TD - optimal design: 415s 0 37.29 64.44 150 415s 0.40070 0.45303 0.09933 0.04694 415s [1] 0.1853293 415s Calculated TD - optimal design: 415s 0 50.22 415s 0.5 0.5 415s Calculated TD - optimal design: 415s 0 0.49 25.2 108.07 415s 0.44787 0.47652 0.05213 0.02348 415s [1] 0.130092 415s Calculated TD - optimal design: 415s 0 27 94.89 150 415s 0.44879 0.47519 0.05121 0.02481 415s [1] 0.5013672 415s Calculated TD - optimal design: 415s 0 0.35 150 415s 0.49865 0.50000 0.00135 415s [1] 0.05572985 415s [1] 4.478701e-01 4.765233e-01 5.212994e-02 2.347673e-02 6.509030e-09 415s [1] 4.478701e-01 4.765233e-01 5.212991e-02 2.347669e-02 5.680431e-09 416s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 416s [1,] 0.246 0.142 0.122 0.000 0.000 0.241 0 0 0.249 416s [2,] 0.248 0.234 0.059 0.211 0.000 0.000 0 0 0.248 416s [3,] 0.247 0.000 0.000 0.224 0.081 0.203 0 0 0.246 416s [4,] 0.250 0.248 0.044 0.210 0.000 0.000 0 0 0.249 416s [5,] 0.250 0.248 0.191 0.064 0.000 0.000 0 0 0.247 416s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 416s [1,] 0.49 0.01 0.00 0.00 0.00 0.00 0.36 0.14 0.00 416s [2,] 0.48 0.02 0.00 0.32 0.18 0.00 0.00 0.00 0.00 416s [3,] 0.21 0.29 0.00 0.00 0.00 0.46 0.04 0.00 0.00 416s [4,] 0.50 0.00 0.49 0.01 0.00 0.00 0.00 0.00 0.00 416s [5,] 0.49 0.02 0.48 0.00 0.00 0.00 0.00 0.00 0.01 416s [1] 0.8823949 417s Calculated D - optimal design: 417s 0 1 417s 0.5 0.5 417s Calculated TD - optimal design: 417s 0 0.25 0.5 1 417s 0.48951 0.35517 0.14483 0.01049 417s testsDesign.R passed 417s Loading required package: DoseFinding 417s [1] 3714.641 417s [1] 3714.641 417s Dose Response Model 417s 417s Model: betaMod 417s Fit-type: normal 417s 417s Residuals: 417s Min 1Q Median 3Q Max 417s -23.368 -3.727 0.129 3.894 16.152 417s 417s Coefficients with approx. stand. error: 417s Estimate Std. Error 417s e0 10.80 0.565 418s eMax 7.41 0.692 418s delta1 2.24 0.589 418s delta2 1.00 0.328 418s 418s Residual standard error: 5.64 418s Degrees of freedom: 585 418s 418s Formula: y ~ betaMod(x, e0, emax, delta1, delta2, 1.2 * max(datset$x)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s e0 10.7964 0.5653 19.098 < 2e-16 *** 418s emax 7.4106 0.6917 10.714 < 2e-16 *** 418s delta1 2.2357 0.5885 3.799 0.000161 *** 418s delta2 1.0047 0.3277 3.066 0.002271 ** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 5.637 on 585 degrees of freedom 418s 418s Number of iterations to convergence: 6 418s Achieved convergence tolerance: 4.025e-06 418s 418s e0 eMax delta1 delta2 418s e0 0.31958673 -0.28252697 0.20809234 0.09247897 418s eMax -0.28252697 0.47843297 -0.04177476 0.01244179 418s delta1 0.20809234 -0.04177476 0.34639417 0.18051781 418s delta2 0.09247897 0.01244179 0.18051781 0.10741016 418s e0 emax delta1 delta2 418s e0 0.31959067 -0.28253043 0.2080897 0.09247786 418s emax -0.28253043 0.47843379 -0.0417750 0.01244127 418s delta1 0.20808969 -0.04177500 0.3463820 0.18051234 418s delta2 0.09247786 0.01244127 0.1805123 0.10740755 418s $fit 418s [1] 6.0578751 6.8058158 7.2227652 6.0578751 3.1444084 6.8058158 7.2227652 418s [8] 3.1444084 6.0578751 0.0000000 6.0578751 6.0578751 7.2227652 3.1444084 418s [15] 0.8440180 0.0000000 6.0578751 3.1444084 3.1444084 0.0000000 7.2227652 418s [22] 0.0000000 7.2227652 6.8058158 6.8058158 3.1444084 6.8058158 6.8058158 418s [29] 3.1444084 6.0578751 7.2227652 6.8058158 3.1444084 3.1444084 3.1444084 418s [36] 0.0000000 0.0000000 3.1444084 6.8058158 3.1444084 3.1444084 0.8440180 418s [43] 3.1444084 6.0578751 3.1444084 6.0578751 0.8440180 7.2227652 0.8440180 418s [50] 0.8440180 0.0000000 7.2227652 6.8058158 6.8058158 7.2227652 3.1444084 418s [57] 7.2227652 6.8058158 0.8440180 0.8440180 3.1444084 0.0000000 7.2227652 418s [64] 6.8058158 6.8058158 6.8058158 0.0000000 7.2227652 3.1444084 6.0578751 418s [71] 0.0000000 0.8440180 0.8440180 6.8058158 3.1444084 3.1444084 6.0578751 418s [78] 0.0000000 6.0578751 6.8058158 6.8058158 3.1444084 3.1444084 3.1444084 418s [85] 3.1444084 7.2227652 6.8058158 0.8440180 0.0000000 0.8440180 7.2227652 418s [92] 6.8058158 3.1444084 7.2227652 6.0578751 6.8058158 6.0578751 6.8058158 418s [99] 6.8058158 6.8058158 3.1444084 6.0578751 6.8058158 0.0000000 6.0578751 418s [106] 6.8058158 0.0000000 6.8058158 3.1444084 3.1444084 0.8440180 6.8058158 418s [113] 6.0578751 3.1444084 0.1731496 6.0578751 6.0578751 0.0000000 6.8058158 418s [120] 0.0000000 0.0000000 6.8058158 0.1731496 0.8440180 0.0000000 6.0578751 418s [127] 6.8058158 3.1444084 6.0578751 0.8440180 6.8058158 0.8440180 7.2227652 418s [134] 6.8058158 3.1444084 6.0578751 6.8058158 7.2227652 6.8058158 0.1731496 418s [141] 6.8058158 6.8058158 0.8440180 6.8058158 6.0578751 7.2227652 6.8058158 418s [148] 3.1444084 3.1444084 0.0000000 6.0578751 3.1444084 0.0000000 3.1444084 418s [155] 6.8058158 7.2227652 6.8058158 0.0000000 0.0000000 0.8440180 3.1444084 418s [162] 0.0000000 0.1731496 3.1444084 3.1444084 6.0578751 0.0000000 0.8440180 418s [169] 0.0000000 3.1444084 3.1444084 6.0578751 6.0578751 0.0000000 7.2227652 418s [176] 0.8440180 0.0000000 6.0578751 0.0000000 7.2227652 0.0000000 3.1444084 418s [183] 6.0578751 6.0578751 3.1444084 3.1444084 0.1731496 7.2227652 3.1444084 418s [190] 0.8440180 7.2227652 7.2227652 0.8440180 0.0000000 7.2227652 3.1444084 418s [197] 7.2227652 7.2227652 0.1731496 3.1444084 0.0000000 7.2227652 3.1444084 418s [204] 6.8058158 6.8058158 7.2227652 6.8058158 7.2227652 0.8440180 6.0578751 418s [211] 3.1444084 3.1444084 3.1444084 0.0000000 0.0000000 6.0578751 6.0578751 418s [218] 3.1444084 3.1444084 0.1731496 7.2227652 7.2227652 0.0000000 0.8440180 418s [225] 7.2227652 0.8440180 3.1444084 0.8440180 0.0000000 7.2227652 3.1444084 418s [232] 6.8058158 6.8058158 3.1444084 0.8440180 6.0578751 0.8440180 0.0000000 418s [239] 0.0000000 6.8058158 7.2227652 6.8058158 6.0578751 3.1444084 7.2227652 418s [246] 6.8058158 3.1444084 7.2227652 0.8440180 0.8440180 7.2227652 6.0578751 418s [253] 0.1731496 7.2227652 6.8058158 6.8058158 7.2227652 6.8058158 6.0578751 418s [260] 6.8058158 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 0.8440180 418s [267] 6.8058158 3.1444084 3.1444084 0.8440180 3.1444084 0.8440180 0.0000000 418s [274] 3.1444084 0.8440180 0.8440180 0.1731496 6.0578751 6.0578751 0.8440180 418s [281] 0.0000000 0.0000000 0.0000000 6.0578751 0.0000000 3.1444084 3.1444084 418s [288] 0.0000000 0.8440180 6.0578751 0.0000000 6.0578751 7.2227652 0.8440180 418s [295] 7.2227652 6.8058158 0.8440180 0.1731496 7.2227652 7.2227652 0.0000000 418s [302] 6.0578751 6.8058158 7.2227652 0.0000000 6.0578751 6.0578751 6.8058158 418s [309] 0.0000000 0.8440180 6.0578751 6.8058158 6.8058158 3.1444084 0.8440180 418s [316] 6.8058158 3.1444084 7.2227652 6.0578751 0.8440180 3.1444084 0.8440180 418s [323] 7.2227652 6.0578751 6.0578751 7.2227652 3.1444084 6.0578751 6.8058158 418s [330] 0.8440180 0.8440180 6.8058158 6.8058158 7.2227652 0.8440180 3.1444084 418s [337] 3.1444084 6.0578751 6.0578751 0.0000000 3.1444084 6.8058158 0.8440180 418s [344] 3.1444084 6.0578751 7.2227652 3.1444084 3.1444084 0.1731496 6.0578751 418s [351] 7.2227652 7.2227652 3.1444084 6.0578751 3.1444084 6.0578751 3.1444084 418s [358] 6.0578751 3.1444084 7.2227652 0.8440180 3.1444084 6.8058158 0.8440180 418s [365] 3.1444084 0.1731496 6.8058158 3.1444084 6.8058158 7.2227652 3.1444084 418s [372] 6.8058158 6.8058158 3.1444084 0.0000000 0.8440180 0.8440180 6.8058158 418s [379] 0.0000000 7.2227652 0.8440180 0.8440180 6.0578751 3.1444084 0.8440180 418s [386] 7.2227652 3.1444084 7.2227652 6.8058158 3.1444084 3.1444084 6.8058158 418s [393] 6.0578751 3.1444084 6.8058158 0.0000000 6.8058158 0.8440180 0.0000000 418s [400] 3.1444084 6.8058158 0.8440180 6.0578751 6.0578751 0.1731496 6.0578751 418s [407] 0.8440180 3.1444084 0.8440180 3.1444084 3.1444084 6.8058158 0.8440180 418s [414] 6.8058158 7.2227652 0.0000000 6.8058158 0.8440180 0.0000000 7.2227652 418s [421] 6.8058158 3.1444084 3.1444084 6.8058158 6.8058158 6.0578751 6.0578751 418s [428] 6.0578751 7.2227652 0.1731496 7.2227652 6.8058158 0.0000000 3.1444084 418s [435] 7.2227652 6.8058158 6.8058158 0.8440180 0.0000000 3.1444084 7.2227652 418s [442] 6.8058158 6.0578751 3.1444084 6.0578751 7.2227652 6.0578751 7.2227652 418s [449] 0.0000000 7.2227652 7.2227652 0.8440180 6.0578751 6.8058158 0.0000000 418s [456] 0.8440180 6.0578751 0.1731496 3.1444084 7.2227652 7.2227652 6.0578751 418s [463] 6.0578751 3.1444084 0.1731496 7.2227652 6.8058158 0.8440180 0.0000000 418s [470] 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 7.2227652 0.8440180 418s [477] 3.1444084 7.2227652 7.2227652 0.1731496 3.1444084 7.2227652 7.2227652 418s [484] 3.1444084 6.8058158 0.0000000 7.2227652 6.0578751 0.8440180 3.1444084 418s [491] 7.2227652 7.2227652 6.0578751 3.1444084 7.2227652 6.0578751 0.0000000 418s [498] 0.8440180 6.0578751 6.8058158 3.1444084 6.0578751 0.0000000 7.2227652 418s [505] 3.1444084 0.0000000 0.8440180 7.2227652 6.8058158 6.8058158 3.1444084 418s [512] 6.8058158 0.1731496 0.0000000 3.1444084 3.1444084 3.1444084 6.8058158 418s [519] 6.8058158 0.0000000 6.8058158 6.8058158 3.1444084 7.2227652 3.1444084 418s [526] 0.8440180 0.8440180 7.2227652 6.0578751 6.0578751 3.1444084 6.8058158 418s [533] 7.2227652 6.0578751 6.8058158 3.1444084 3.1444084 3.1444084 7.2227652 418s [540] 0.0000000 0.0000000 6.8058158 3.1444084 0.1731496 0.0000000 6.0578751 418s [547] 7.2227652 6.0578751 6.0578751 7.2227652 6.0578751 6.0578751 6.8058158 418s [554] 0.0000000 0.0000000 3.1444084 6.0578751 7.2227652 7.2227652 3.1444084 418s [561] 3.1444084 6.8058158 7.2227652 6.8058158 6.8058158 0.0000000 6.8058158 418s [568] 3.1444084 7.2227652 0.8440180 0.0000000 3.1444084 0.8440180 6.8058158 418s [575] 7.2227652 3.1444084 6.0578751 0.8440180 6.8058158 3.1444084 0.0000000 418s [582] 7.2227652 6.8058158 0.8440180 6.0578751 3.1444084 6.8058158 0.8440180 418s [589] 6.0578751 418s 418s $se.fit 418s [1] 0.7643614 0.6580335 0.7488551 0.7643614 0.7997224 0.6580335 0.7488551 418s [8] 0.7997224 0.7643614 0.0000000 0.7643614 0.7643614 0.7488551 0.7997224 418s [15] 0.4790120 0.0000000 0.7643614 0.7997224 0.7997224 0.0000000 0.7488551 418s [22] 0.0000000 0.7488551 0.6580335 0.6580335 0.7997224 0.6580335 0.6580335 418s [29] 0.7997224 0.7643614 0.7488551 0.6580335 0.7997224 0.7997224 0.7997224 418s [36] 0.0000000 0.0000000 0.7997224 0.6580335 0.7997224 0.7997224 0.4790120 418s [43] 0.7997224 0.7643614 0.7997224 0.7643614 0.4790120 0.7488551 0.4790120 418s [50] 0.4790120 0.0000000 0.7488551 0.6580335 0.6580335 0.7488551 0.7997224 418s [57] 0.7488551 0.6580335 0.4790120 0.4790120 0.7997224 0.0000000 0.7488551 418s [64] 0.6580335 0.6580335 0.6580335 0.0000000 0.7488551 0.7997224 0.7643614 418s [71] 0.0000000 0.4790120 0.4790120 0.6580335 0.7997224 0.7997224 0.7643614 418s [78] 0.0000000 0.7643614 0.6580335 0.6580335 0.7997224 0.7997224 0.7997224 418s [85] 0.7997224 0.7488551 0.6580335 0.4790120 0.0000000 0.4790120 0.7488551 418s [92] 0.6580335 0.7997224 0.7488551 0.7643614 0.6580335 0.7643614 0.6580335 418s [99] 0.6580335 0.6580335 0.7997224 0.7643614 0.6580335 0.0000000 0.7643614 418s [106] 0.6580335 0.0000000 0.6580335 0.7997224 0.7997224 0.4790120 0.6580335 418s [113] 0.7643614 0.7997224 0.1680259 0.7643614 0.7643614 0.0000000 0.6580335 418s [120] 0.0000000 0.0000000 0.6580335 0.1680259 0.4790120 0.0000000 0.7643614 418s [127] 0.6580335 0.7997224 0.7643614 0.4790120 0.6580335 0.4790120 0.7488551 418s [134] 0.6580335 0.7997224 0.7643614 0.6580335 0.7488551 0.6580335 0.1680259 418s [141] 0.6580335 0.6580335 0.4790120 0.6580335 0.7643614 0.7488551 0.6580335 418s [148] 0.7997224 0.7997224 0.0000000 0.7643614 0.7997224 0.0000000 0.7997224 418s [155] 0.6580335 0.7488551 0.6580335 0.0000000 0.0000000 0.4790120 0.7997224 418s [162] 0.0000000 0.1680259 0.7997224 0.7997224 0.7643614 0.0000000 0.4790120 418s [169] 0.0000000 0.7997224 0.7997224 0.7643614 0.7643614 0.0000000 0.7488551 418s [176] 0.4790120 0.0000000 0.7643614 0.0000000 0.7488551 0.0000000 0.7997224 418s [183] 0.7643614 0.7643614 0.7997224 0.7997224 0.1680259 0.7488551 0.7997224 418s [190] 0.4790120 0.7488551 0.7488551 0.4790120 0.0000000 0.7488551 0.7997224 418s [197] 0.7488551 0.7488551 0.1680259 0.7997224 0.0000000 0.7488551 0.7997224 418s [204] 0.6580335 0.6580335 0.7488551 0.6580335 0.7488551 0.4790120 0.7643614 418s [211] 0.7997224 0.7997224 0.7997224 0.0000000 0.0000000 0.7643614 0.7643614 418s [218] 0.7997224 0.7997224 0.1680259 0.7488551 0.7488551 0.0000000 0.4790120 418s [225] 0.7488551 0.4790120 0.7997224 0.4790120 0.0000000 0.7488551 0.7997224 418s [232] 0.6580335 0.6580335 0.7997224 0.4790120 0.7643614 0.4790120 0.0000000 418s [239] 0.0000000 0.6580335 0.7488551 0.6580335 0.7643614 0.7997224 0.7488551 418s [246] 0.6580335 0.7997224 0.7488551 0.4790120 0.4790120 0.7488551 0.7643614 418s [253] 0.1680259 0.7488551 0.6580335 0.6580335 0.7488551 0.6580335 0.7643614 418s [260] 0.6580335 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.4790120 418s [267] 0.6580335 0.7997224 0.7997224 0.4790120 0.7997224 0.4790120 0.0000000 418s [274] 0.7997224 0.4790120 0.4790120 0.1680259 0.7643614 0.7643614 0.4790120 418s [281] 0.0000000 0.0000000 0.0000000 0.7643614 0.0000000 0.7997224 0.7997224 418s [288] 0.0000000 0.4790120 0.7643614 0.0000000 0.7643614 0.7488551 0.4790120 418s [295] 0.7488551 0.6580335 0.4790120 0.1680259 0.7488551 0.7488551 0.0000000 418s [302] 0.7643614 0.6580335 0.7488551 0.0000000 0.7643614 0.7643614 0.6580335 418s [309] 0.0000000 0.4790120 0.7643614 0.6580335 0.6580335 0.7997224 0.4790120 418s [316] 0.6580335 0.7997224 0.7488551 0.7643614 0.4790120 0.7997224 0.4790120 418s [323] 0.7488551 0.7643614 0.7643614 0.7488551 0.7997224 0.7643614 0.6580335 418s [330] 0.4790120 0.4790120 0.6580335 0.6580335 0.7488551 0.4790120 0.7997224 418s [337] 0.7997224 0.7643614 0.7643614 0.0000000 0.7997224 0.6580335 0.4790120 418s [344] 0.7997224 0.7643614 0.7488551 0.7997224 0.7997224 0.1680259 0.7643614 418s [351] 0.7488551 0.7488551 0.7997224 0.7643614 0.7997224 0.7643614 0.7997224 418s [358] 0.7643614 0.7997224 0.7488551 0.4790120 0.7997224 0.6580335 0.4790120 418s [365] 0.7997224 0.1680259 0.6580335 0.7997224 0.6580335 0.7488551 0.7997224 418s [372] 0.6580335 0.6580335 0.7997224 0.0000000 0.4790120 0.4790120 0.6580335 418s [379] 0.0000000 0.7488551 0.4790120 0.4790120 0.7643614 0.7997224 0.4790120 418s [386] 0.7488551 0.7997224 0.7488551 0.6580335 0.7997224 0.7997224 0.6580335 418s [393] 0.7643614 0.7997224 0.6580335 0.0000000 0.6580335 0.4790120 0.0000000 418s [400] 0.7997224 0.6580335 0.4790120 0.7643614 0.7643614 0.1680259 0.7643614 418s [407] 0.4790120 0.7997224 0.4790120 0.7997224 0.7997224 0.6580335 0.4790120 418s [414] 0.6580335 0.7488551 0.0000000 0.6580335 0.4790120 0.0000000 0.7488551 418s [421] 0.6580335 0.7997224 0.7997224 0.6580335 0.6580335 0.7643614 0.7643614 418s [428] 0.7643614 0.7488551 0.1680259 0.7488551 0.6580335 0.0000000 0.7997224 418s [435] 0.7488551 0.6580335 0.6580335 0.4790120 0.0000000 0.7997224 0.7488551 418s [442] 0.6580335 0.7643614 0.7997224 0.7643614 0.7488551 0.7643614 0.7488551 418s [449] 0.0000000 0.7488551 0.7488551 0.4790120 0.7643614 0.6580335 0.0000000 418s [456] 0.4790120 0.7643614 0.1680259 0.7997224 0.7488551 0.7488551 0.7643614 418s [463] 0.7643614 0.7997224 0.1680259 0.7488551 0.6580335 0.4790120 0.0000000 418s [470] 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.7488551 0.4790120 418s [477] 0.7997224 0.7488551 0.7488551 0.1680259 0.7997224 0.7488551 0.7488551 418s [484] 0.7997224 0.6580335 0.0000000 0.7488551 0.7643614 0.4790120 0.7997224 418s [491] 0.7488551 0.7488551 0.7643614 0.7997224 0.7488551 0.7643614 0.0000000 418s [498] 0.4790120 0.7643614 0.6580335 0.7997224 0.7643614 0.0000000 0.7488551 418s [505] 0.7997224 0.0000000 0.4790120 0.7488551 0.6580335 0.6580335 0.7997224 418s [512] 0.6580335 0.1680259 0.0000000 0.7997224 0.7997224 0.7997224 0.6580335 418s [519] 0.6580335 0.0000000 0.6580335 0.6580335 0.7997224 0.7488551 0.7997224 418s [526] 0.4790120 0.4790120 0.7488551 0.7643614 0.7643614 0.7997224 0.6580335 418s [533] 0.7488551 0.7643614 0.6580335 0.7997224 0.7997224 0.7997224 0.7488551 418s [540] 0.0000000 0.0000000 0.6580335 0.7997224 0.1680259 0.0000000 0.7643614 418s [547] 0.7488551 0.7643614 0.7643614 0.7488551 0.7643614 0.7643614 0.6580335 418s [554] 0.0000000 0.0000000 0.7997224 0.7643614 0.7488551 0.7488551 0.7997224 418s [561] 0.7997224 0.6580335 0.7488551 0.6580335 0.6580335 0.0000000 0.6580335 418s [568] 0.7997224 0.7488551 0.4790120 0.0000000 0.7997224 0.4790120 0.6580335 418s [575] 0.7488551 0.7997224 0.7643614 0.4790120 0.6580335 0.7997224 0.0000000 418s [582] 0.7488551 0.6580335 0.4790120 0.7643614 0.7997224 0.6580335 0.4790120 418s [589] 0.7643614 418s 418s $fit 418s [1] 16.85434 17.60229 18.01923 16.85434 13.94088 17.60229 18.01923 13.94088 418s [9] 16.85434 10.79647 16.85434 16.85434 18.01923 13.94088 11.64049 10.79647 418s [17] 16.85434 13.94088 13.94088 10.79647 18.01923 10.79647 18.01923 17.60229 418s [25] 17.60229 13.94088 17.60229 17.60229 13.94088 16.85434 18.01923 17.60229 418s [33] 13.94088 13.94088 13.94088 10.79647 10.79647 13.94088 17.60229 13.94088 418s [41] 13.94088 11.64049 13.94088 16.85434 13.94088 16.85434 11.64049 18.01923 418s [49] 11.64049 11.64049 10.79647 18.01923 17.60229 17.60229 18.01923 13.94088 418s [57] 18.01923 17.60229 11.64049 11.64049 13.94088 10.79647 18.01923 17.60229 418s [65] 17.60229 17.60229 10.79647 18.01923 13.94088 16.85434 10.79647 11.64049 418s [73] 11.64049 17.60229 13.94088 13.94088 16.85434 10.79647 16.85434 17.60229 418s [81] 17.60229 13.94088 13.94088 13.94088 13.94088 18.01923 17.60229 11.64049 418s [89] 10.79647 11.64049 18.01923 17.60229 13.94088 18.01923 16.85434 17.60229 418s [97] 16.85434 17.60229 17.60229 17.60229 13.94088 16.85434 17.60229 10.79647 418s [105] 16.85434 17.60229 10.79647 17.60229 13.94088 13.94088 11.64049 17.60229 418s [113] 16.85434 13.94088 10.96962 16.85434 16.85434 10.79647 17.60229 10.79647 418s [121] 10.79647 17.60229 10.96962 11.64049 10.79647 16.85434 17.60229 13.94088 418s [129] 16.85434 11.64049 17.60229 11.64049 18.01923 17.60229 13.94088 16.85434 418s [137] 17.60229 18.01923 17.60229 10.96962 17.60229 17.60229 11.64049 17.60229 418s [145] 16.85434 18.01923 17.60229 13.94088 13.94088 10.79647 16.85434 13.94088 418s [153] 10.79647 13.94088 17.60229 18.01923 17.60229 10.79647 10.79647 11.64049 418s [161] 13.94088 10.79647 10.96962 13.94088 13.94088 16.85434 10.79647 11.64049 418s [169] 10.79647 13.94088 13.94088 16.85434 16.85434 10.79647 18.01923 11.64049 418s [177] 10.79647 16.85434 10.79647 18.01923 10.79647 13.94088 16.85434 16.85434 418s [185] 13.94088 13.94088 10.96962 18.01923 13.94088 11.64049 18.01923 18.01923 418s [193] 11.64049 10.79647 18.01923 13.94088 18.01923 18.01923 10.96962 13.94088 418s [201] 10.79647 18.01923 13.94088 17.60229 17.60229 18.01923 17.60229 18.01923 418s [209] 11.64049 16.85434 13.94088 13.94088 13.94088 10.79647 10.79647 16.85434 418s [217] 16.85434 13.94088 13.94088 10.96962 18.01923 18.01923 10.79647 11.64049 418s [225] 18.01923 11.64049 13.94088 11.64049 10.79647 18.01923 13.94088 17.60229 418s [233] 17.60229 13.94088 11.64049 16.85434 11.64049 10.79647 10.79647 17.60229 418s [241] 18.01923 17.60229 16.85434 13.94088 18.01923 17.60229 13.94088 18.01923 418s [249] 11.64049 11.64049 18.01923 16.85434 10.96962 18.01923 17.60229 17.60229 418s [257] 18.01923 17.60229 16.85434 17.60229 11.64049 17.60229 17.60229 18.01923 418s [265] 16.85434 11.64049 17.60229 13.94088 13.94088 11.64049 13.94088 11.64049 418s [273] 10.79647 13.94088 11.64049 11.64049 10.96962 16.85434 16.85434 11.64049 418s [281] 10.79647 10.79647 10.79647 16.85434 10.79647 13.94088 13.94088 10.79647 418s [289] 11.64049 16.85434 10.79647 16.85434 18.01923 11.64049 18.01923 17.60229 418s [297] 11.64049 10.96962 18.01923 18.01923 10.79647 16.85434 17.60229 18.01923 418s [305] 10.79647 16.85434 16.85434 17.60229 10.79647 11.64049 16.85434 17.60229 418s [313] 17.60229 13.94088 11.64049 17.60229 13.94088 18.01923 16.85434 11.64049 418s [321] 13.94088 11.64049 18.01923 16.85434 16.85434 18.01923 13.94088 16.85434 418s [329] 17.60229 11.64049 11.64049 17.60229 17.60229 18.01923 11.64049 13.94088 418s [337] 13.94088 16.85434 16.85434 10.79647 13.94088 17.60229 11.64049 13.94088 418s [345] 16.85434 18.01923 13.94088 13.94088 10.96962 16.85434 18.01923 18.01923 418s [353] 13.94088 16.85434 13.94088 16.85434 13.94088 16.85434 13.94088 18.01923 418s [361] 11.64049 13.94088 17.60229 11.64049 13.94088 10.96962 17.60229 13.94088 418s [369] 17.60229 18.01923 13.94088 17.60229 17.60229 13.94088 10.79647 11.64049 418s [377] 11.64049 17.60229 10.79647 18.01923 11.64049 11.64049 16.85434 13.94088 418s [385] 11.64049 18.01923 13.94088 18.01923 17.60229 13.94088 13.94088 17.60229 418s [393] 16.85434 13.94088 17.60229 10.79647 17.60229 11.64049 10.79647 13.94088 418s [401] 17.60229 11.64049 16.85434 16.85434 10.96962 16.85434 11.64049 13.94088 418s [409] 11.64049 13.94088 13.94088 17.60229 11.64049 17.60229 18.01923 10.79647 418s [417] 17.60229 11.64049 10.79647 18.01923 17.60229 13.94088 13.94088 17.60229 418s [425] 17.60229 16.85434 16.85434 16.85434 18.01923 10.96962 18.01923 17.60229 418s [433] 10.79647 13.94088 18.01923 17.60229 17.60229 11.64049 10.79647 13.94088 418s [441] 18.01923 17.60229 16.85434 13.94088 16.85434 18.01923 16.85434 18.01923 418s [449] 10.79647 18.01923 18.01923 11.64049 16.85434 17.60229 10.79647 11.64049 418s [457] 16.85434 10.96962 13.94088 18.01923 18.01923 16.85434 16.85434 13.94088 418s [465] 10.96962 18.01923 17.60229 11.64049 10.79647 11.64049 17.60229 17.60229 418s [473] 18.01923 16.85434 18.01923 11.64049 13.94088 18.01923 18.01923 10.96962 418s [481] 13.94088 18.01923 18.01923 13.94088 17.60229 10.79647 18.01923 16.85434 418s [489] 11.64049 13.94088 18.01923 18.01923 16.85434 13.94088 18.01923 16.85434 418s [497] 10.79647 11.64049 16.85434 17.60229 13.94088 16.85434 10.79647 18.01923 418s [505] 13.94088 10.79647 11.64049 18.01923 17.60229 17.60229 13.94088 17.60229 418s [513] 10.96962 10.79647 13.94088 13.94088 13.94088 17.60229 17.60229 10.79647 418s [521] 17.60229 17.60229 13.94088 18.01923 13.94088 11.64049 11.64049 18.01923 418s [529] 16.85434 16.85434 13.94088 17.60229 18.01923 16.85434 17.60229 13.94088 418s [537] 13.94088 13.94088 18.01923 10.79647 10.79647 17.60229 13.94088 10.96962 418s [545] 10.79647 16.85434 18.01923 16.85434 16.85434 18.01923 16.85434 16.85434 418s [553] 17.60229 10.79647 10.79647 13.94088 16.85434 18.01923 18.01923 13.94088 418s [561] 13.94088 17.60229 18.01923 17.60229 17.60229 10.79647 17.60229 13.94088 418s [569] 18.01923 11.64049 10.79647 13.94088 11.64049 17.60229 18.01923 13.94088 418s [577] 16.85434 11.64049 17.60229 13.94088 10.79647 18.01923 17.60229 11.64049 418s [585] 16.85434 13.94088 17.60229 11.64049 16.85434 418s 418s $se.fit 418s [1] 0.4716508 0.3621952 0.5408090 0.4716508 0.4610877 0.3621952 0.5408090 418s [8] 0.4610877 0.4716508 0.5653200 0.4716508 0.4716508 0.5408090 0.4610877 418s [15] 0.3763389 0.5653200 0.4716508 0.4610877 0.4610877 0.5653200 0.5408090 418s [22] 0.5653200 0.5408090 0.3621952 0.3621952 0.4610877 0.3621952 0.3621952 418s [29] 0.4610877 0.4716508 0.5408090 0.3621952 0.4610877 0.4610877 0.4610877 418s [36] 0.5653200 0.5653200 0.4610877 0.3621952 0.4610877 0.4610877 0.3763389 418s [43] 0.4610877 0.4716508 0.4610877 0.4716508 0.3763389 0.5408090 0.3763389 418s [50] 0.3763389 0.5653200 0.5408090 0.3621952 0.3621952 0.5408090 0.4610877 418s [57] 0.5408090 0.3621952 0.3763389 0.3763389 0.4610877 0.5653200 0.5408090 418s [64] 0.3621952 0.3621952 0.3621952 0.5653200 0.5408090 0.4610877 0.4716508 418s [71] 0.5653200 0.3763389 0.3763389 0.3621952 0.4610877 0.4610877 0.4716508 418s [78] 0.5653200 0.4716508 0.3621952 0.3621952 0.4610877 0.4610877 0.4610877 418s [85] 0.4610877 0.5408090 0.3621952 0.3763389 0.5653200 0.3763389 0.5408090 418s [92] 0.3621952 0.4610877 0.5408090 0.4716508 0.3621952 0.4716508 0.3621952 418s [99] 0.3621952 0.3621952 0.4610877 0.4716508 0.3621952 0.5653200 0.4716508 418s [106] 0.3621952 0.5653200 0.3621952 0.4610877 0.4610877 0.3763389 0.3621952 418s [113] 0.4716508 0.4610877 0.4616804 0.4716508 0.4716508 0.5653200 0.3621952 418s [120] 0.5653200 0.5653200 0.3621952 0.4616804 0.3763389 0.5653200 0.4716508 418s [127] 0.3621952 0.4610877 0.4716508 0.3763389 0.3621952 0.3763389 0.5408090 418s [134] 0.3621952 0.4610877 0.4716508 0.3621952 0.5408090 0.3621952 0.4616804 418s [141] 0.3621952 0.3621952 0.3763389 0.3621952 0.4716508 0.5408090 0.3621952 418s [148] 0.4610877 0.4610877 0.5653200 0.4716508 0.4610877 0.5653200 0.4610877 418s [155] 0.3621952 0.5408090 0.3621952 0.5653200 0.5653200 0.3763389 0.4610877 418s [162] 0.5653200 0.4616804 0.4610877 0.4610877 0.4716508 0.5653200 0.3763389 418s [169] 0.5653200 0.4610877 0.4610877 0.4716508 0.4716508 0.5653200 0.5408090 418s [176] 0.3763389 0.5653200 0.4716508 0.5653200 0.5408090 0.5653200 0.4610877 418s [183] 0.4716508 0.4716508 0.4610877 0.4610877 0.4616804 0.5408090 0.4610877 418s [190] 0.3763389 0.5408090 0.5408090 0.3763389 0.5653200 0.5408090 0.4610877 418s [197] 0.5408090 0.5408090 0.4616804 0.4610877 0.5653200 0.5408090 0.4610877 418s [204] 0.3621952 0.3621952 0.5408090 0.3621952 0.5408090 0.3763389 0.4716508 418s [211] 0.4610877 0.4610877 0.4610877 0.5653200 0.5653200 0.4716508 0.4716508 418s [218] 0.4610877 0.4610877 0.4616804 0.5408090 0.5408090 0.5653200 0.3763389 418s [225] 0.5408090 0.3763389 0.4610877 0.3763389 0.5653200 0.5408090 0.4610877 418s [232] 0.3621952 0.3621952 0.4610877 0.3763389 0.4716508 0.3763389 0.5653200 418s [239] 0.5653200 0.3621952 0.5408090 0.3621952 0.4716508 0.4610877 0.5408090 418s [246] 0.3621952 0.4610877 0.5408090 0.3763389 0.3763389 0.5408090 0.4716508 418s [253] 0.4616804 0.5408090 0.3621952 0.3621952 0.5408090 0.3621952 0.4716508 418s [260] 0.3621952 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.3763389 418s [267] 0.3621952 0.4610877 0.4610877 0.3763389 0.4610877 0.3763389 0.5653200 418s [274] 0.4610877 0.3763389 0.3763389 0.4616804 0.4716508 0.4716508 0.3763389 418s [281] 0.5653200 0.5653200 0.5653200 0.4716508 0.5653200 0.4610877 0.4610877 418s [288] 0.5653200 0.3763389 0.4716508 0.5653200 0.4716508 0.5408090 0.3763389 418s [295] 0.5408090 0.3621952 0.3763389 0.4616804 0.5408090 0.5408090 0.5653200 418s [302] 0.4716508 0.3621952 0.5408090 0.5653200 0.4716508 0.4716508 0.3621952 418s [309] 0.5653200 0.3763389 0.4716508 0.3621952 0.3621952 0.4610877 0.3763389 418s [316] 0.3621952 0.4610877 0.5408090 0.4716508 0.3763389 0.4610877 0.3763389 418s [323] 0.5408090 0.4716508 0.4716508 0.5408090 0.4610877 0.4716508 0.3621952 418s [330] 0.3763389 0.3763389 0.3621952 0.3621952 0.5408090 0.3763389 0.4610877 418s [337] 0.4610877 0.4716508 0.4716508 0.5653200 0.4610877 0.3621952 0.3763389 418s [344] 0.4610877 0.4716508 0.5408090 0.4610877 0.4610877 0.4616804 0.4716508 418s [351] 0.5408090 0.5408090 0.4610877 0.4716508 0.4610877 0.4716508 0.4610877 418s [358] 0.4716508 0.4610877 0.5408090 0.3763389 0.4610877 0.3621952 0.3763389 418s [365] 0.4610877 0.4616804 0.3621952 0.4610877 0.3621952 0.5408090 0.4610877 418s [372] 0.3621952 0.3621952 0.4610877 0.5653200 0.3763389 0.3763389 0.3621952 418s [379] 0.5653200 0.5408090 0.3763389 0.3763389 0.4716508 0.4610877 0.3763389 418s [386] 0.5408090 0.4610877 0.5408090 0.3621952 0.4610877 0.4610877 0.3621952 418s [393] 0.4716508 0.4610877 0.3621952 0.5653200 0.3621952 0.3763389 0.5653200 418s [400] 0.4610877 0.3621952 0.3763389 0.4716508 0.4716508 0.4616804 0.4716508 418s [407] 0.3763389 0.4610877 0.3763389 0.4610877 0.4610877 0.3621952 0.3763389 418s [414] 0.3621952 0.5408090 0.5653200 0.3621952 0.3763389 0.5653200 0.5408090 418s [421] 0.3621952 0.4610877 0.4610877 0.3621952 0.3621952 0.4716508 0.4716508 418s [428] 0.4716508 0.5408090 0.4616804 0.5408090 0.3621952 0.5653200 0.4610877 418s [435] 0.5408090 0.3621952 0.3621952 0.3763389 0.5653200 0.4610877 0.5408090 418s [442] 0.3621952 0.4716508 0.4610877 0.4716508 0.5408090 0.4716508 0.5408090 418s [449] 0.5653200 0.5408090 0.5408090 0.3763389 0.4716508 0.3621952 0.5653200 418s [456] 0.3763389 0.4716508 0.4616804 0.4610877 0.5408090 0.5408090 0.4716508 418s [463] 0.4716508 0.4610877 0.4616804 0.5408090 0.3621952 0.3763389 0.5653200 418s [470] 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.5408090 0.3763389 418s [477] 0.4610877 0.5408090 0.5408090 0.4616804 0.4610877 0.5408090 0.5408090 418s [484] 0.4610877 0.3621952 0.5653200 0.5408090 0.4716508 0.3763389 0.4610877 418s [491] 0.5408090 0.5408090 0.4716508 0.4610877 0.5408090 0.4716508 0.5653200 418s [498] 0.3763389 0.4716508 0.3621952 0.4610877 0.4716508 0.5653200 0.5408090 418s [505] 0.4610877 0.5653200 0.3763389 0.5408090 0.3621952 0.3621952 0.4610877 418s [512] 0.3621952 0.4616804 0.5653200 0.4610877 0.4610877 0.4610877 0.3621952 418s [519] 0.3621952 0.5653200 0.3621952 0.3621952 0.4610877 0.5408090 0.4610877 418s [526] 0.3763389 0.3763389 0.5408090 0.4716508 0.4716508 0.4610877 0.3621952 418s [533] 0.5408090 0.4716508 0.3621952 0.4610877 0.4610877 0.4610877 0.5408090 418s [540] 0.5653200 0.5653200 0.3621952 0.4610877 0.4616804 0.5653200 0.4716508 418s [547] 0.5408090 0.4716508 0.4716508 0.5408090 0.4716508 0.4716508 0.3621952 418s [554] 0.5653200 0.5653200 0.4610877 0.4716508 0.5408090 0.5408090 0.4610877 418s [561] 0.4610877 0.3621952 0.5408090 0.3621952 0.3621952 0.5653200 0.3621952 418s [568] 0.4610877 0.5408090 0.3763389 0.5653200 0.4610877 0.3763389 0.3621952 418s [575] 0.5408090 0.4610877 0.4716508 0.3763389 0.3621952 0.4610877 0.5653200 418s [582] 0.5408090 0.3621952 0.3763389 0.4716508 0.4610877 0.3621952 0.3763389 418s [589] 0.4716508 418s 418s [1] 64.48518 418s [1] 3722.867 418s [1] 3722.867 418s Dose Response Model 418s 418s Model: betaMod 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -23.081 -4.023 0.069 3.767 16.317 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 1.02e+01 0.82024 418s eMax 7.36e+00 0.69530 418s delta1 2.25e+00 0.60058 418s delta2 1.01e+00 0.33271 418s age 5.72e-04 0.00829 418s centergreen 7.41e-01 0.73739 418s centerred 8.30e-01 0.74509 418s centersilver 7.30e-01 0.70097 418s centeryellow 6.56e-01 0.73274 418s 418s Residual standard error: 5.65 418s Degrees of freedom: 580 418s 418s Formula: y ~ cbind(XX, betaMod(x, 0, 1, delta1, delta2, scl)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s delta1 2.253e+00 6.006e-01 3.751 0.000194 *** 418s delta2 1.006e+00 3.327e-01 3.025 0.002600 ** 418s .lin.(Intercept) 1.023e+01 8.202e-01 12.470 < 2e-16 *** 418s .lin.centergreen 7.409e-01 7.374e-01 1.005 0.315410 418s .lin.centerred 8.298e-01 7.451e-01 1.114 0.265866 418s .lin.centersilver 7.301e-01 7.010e-01 1.042 0.298051 418s .lin.centeryellow 6.562e-01 7.327e-01 0.896 0.370886 418s .lin.age 5.723e-04 8.288e-03 0.069 0.944970 418s .lin7 7.357e+00 6.953e-01 10.581 < 2e-16 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 5.653 on 580 degrees of freedom 418s 418s Number of iterations to convergence: 6 418s Achieved convergence tolerance: 9.483e-06 418s 418s e0 eMax delta1 delta2 418s e0 0.672788555 -0.2729452008 2.029556e-01 8.893435e-02 418s eMax -0.272945201 0.4834404095 -4.411253e-02 1.212204e-02 418s delta1 0.202955602 -0.0441125317 3.606932e-01 1.869163e-01 418s delta2 0.088934352 0.0121220371 1.869163e-01 1.106931e-01 418s age -0.003530727 0.0001030079 4.984077e-05 7.767012e-05 418s centergreen -0.234450342 -0.0348602441 1.207912e-02 1.405608e-03 418s centerred -0.253662862 -0.0121021694 6.628052e-04 -2.474391e-03 418s centersilver -0.222055302 -0.0379891034 1.347032e-02 4.810797e-03 418s centeryellow -0.242096858 -0.0036488338 1.244170e-02 2.099443e-03 418s age centergreen centerred centersilver 418s e0 -3.530727e-03 -0.2344503416 -0.2536628616 -2.220553e-01 418s eMax 1.030079e-04 -0.0348602441 -0.0121021694 -3.798910e-02 418s delta1 4.984077e-05 0.0120791216 0.0006628052 1.347032e-02 418s delta2 7.767012e-05 0.0014056079 -0.0024743906 4.810797e-03 418s age 6.868689e-05 0.0001513555 0.0001912581 -2.484136e-05 418s centergreen 1.513555e-04 0.5437481113 0.2513884520 2.524566e-01 418s centerred 1.912581e-04 0.2513884520 0.5551521388 2.504165e-01 418s centersilver -2.484136e-05 0.2524565639 0.2504164883 4.913597e-01 418s centeryellow -1.767809e-05 0.2510775793 0.2504115027 2.500668e-01 418s centeryellow 418s e0 -2.420969e-01 418s eMax -3.648834e-03 418s delta1 1.244170e-02 418s delta2 2.099443e-03 418s age -1.767809e-05 418s centergreen 2.510776e-01 418s centerred 2.504115e-01 418s centersilver 2.500668e-01 418s centeryellow 5.369021e-01 418s delta1 delta2 .lin.(Intercept) .lin.centergreen 418s delta1 3.606961e-01 1.869176e-01 0.202956175 0.0120792619 418s delta2 1.869176e-01 1.106938e-01 0.088934647 0.0014056742 418s .lin.(Intercept) 2.029562e-01 8.893465e-02 0.672787602 -0.2344503742 418s .lin.centergreen 1.207926e-02 1.405674e-03 -0.234450374 0.5437481112 418s .lin.centerred 6.627069e-04 -2.474441e-03 -0.253662950 0.2513884457 418s .lin.centersilver 1.347037e-02 4.810825e-03 -0.222055391 0.2524565593 418s .lin.centeryellow 1.244156e-02 2.099364e-03 -0.242097015 0.2510775716 418s .lin.age 4.984143e-05 7.767047e-05 -0.003530726 0.0001513556 418s .lin7 -4.411219e-02 1.212231e-02 -0.272944257 -0.0348602206 418s .lin.centerred .lin.centersilver .lin.centeryellow 418s delta1 0.0006627069 1.347037e-02 1.244156e-02 418s delta2 -0.0024744411 4.810825e-03 2.099364e-03 418s .lin.(Intercept) -0.2536629505 -2.220554e-01 -2.420970e-01 418s .lin.centergreen 0.2513884457 2.524566e-01 2.510776e-01 418s .lin.centerred 0.5551521364 2.504165e-01 2.504115e-01 418s .lin.centersilver 0.2504164813 4.913597e-01 2.500668e-01 418s .lin.centeryellow 0.2504114958 2.500668e-01 5.369021e-01 418s .lin.age 0.0001912581 -2.484131e-05 -1.767806e-05 418s .lin7 -0.0121021553 -3.798903e-02 -3.648776e-03 418s .lin.age .lin7 418s delta1 4.984143e-05 -0.0441121927 418s delta2 7.767047e-05 0.0121223132 418s .lin.(Intercept) -3.530726e-03 -0.2729442573 418s .lin.centergreen 1.513556e-04 -0.0348602206 418s .lin.centerred 1.912581e-04 -0.0121021553 418s .lin.centersilver -2.484131e-05 -0.0379890347 418s .lin.centeryellow -1.767806e-05 -0.0036487765 418s .lin.age 6.868689e-05 0.0001030081 418s .lin7 1.030081e-04 0.4834404610 418s $fit 418s [1] 0.000000 2.289162 418s 418s $se.fit 418s [1] 0.0000000 0.7519464 418s 418s $fit 418s [1] 10.91275 13.20191 418s 418s $se.fit 418s [1] 0.7364602 0.6423551 418s 418s [1] 65.39866 418s [1] -485.5937 418s [1] -485.5937 418s Dose Response Model 418s 418s Model: emax 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -0.0666 -0.0180 -0.0011 0.0193 0.0692 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -0.5830 6.00e-03 418s eMax 0.0163 3.36e-02 418s ed50 286.5994 1.91e+03 418s 418s Residual standard error: 0.0281 418s Degrees of freedom: 111 418s 418s Formula: y ~ emax(x, e0, emax, ed50) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s e0 -0.58297 0.00600 -97.164 <2e-16 *** 418s emax 0.01632 0.03356 0.486 0.628 418s ed50 286.46623 1905.12541 0.150 0.881 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.02814 on 111 degrees of freedom 418s 418s Number of iterations to convergence: 8 418s Achieved convergence tolerance: 9.285e-06 418s 418s e0 eMax ed50 418s e0 3.599786e-05 -2.913476e-05 1.313843e+00 418s eMax -2.913476e-05 1.126946e-03 6.130312e+01 418s ed50 1.313843e+00 6.130312e+01 3.631673e+06 418s e0 emax ed50 418s e0 3.599786e-05 -2.914111e-05 1.313042e+00 418s emax -2.914111e-05 1.126337e-03 6.126751e+01 418s ed50 1.313042e+00 6.126751e+01 3.629503e+06 418s $fit 418s [1] 0.01155472 0.01155472 0.00000000 0.01155472 0.01155472 0.01155472 418s [7] 0.01056820 0.01056820 0.01056820 0.01155472 0.01239306 0.01056820 418s [13] 0.00000000 0.01239306 0.01155472 0.01056820 0.01056820 0.00000000 418s [19] 0.01155472 0.01212084 0.01212084 0.01056820 0.00000000 0.01155472 418s [25] 0.01056820 0.01056820 0.01155472 0.00000000 0.00000000 0.01155472 418s [31] 0.01056820 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 418s [37] 0.01155472 0.01212084 0.00000000 0.01155472 0.01239306 0.01155472 418s [43] 0.01056820 0.01056820 0.01155472 0.01155472 0.01155472 0.00000000 418s [49] 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 0.01239306 418s [55] 0.00000000 0.01056820 0.01155472 0.01056820 0.01239306 0.01239306 418s [61] 0.01056820 0.01239306 0.01056820 0.01155472 0.01212084 0.01155472 418s [67] 0.01056820 0.01056820 0.01239306 0.01056820 0.00000000 0.01155472 418s [73] 0.01239306 0.01155472 0.01155472 0.01056820 0.00000000 0.00000000 418s [79] 0.01155472 0.00000000 0.00000000 0.00000000 0.01155472 0.01155472 418s [85] 0.01056820 0.01056820 0.01155472 0.01056820 0.01155472 0.01155472 418s [91] 0.01212084 0.01155472 0.01212084 0.01056820 0.00000000 0.01155472 418s [97] 0.01155472 0.01056820 0.01155472 0.00000000 0.01155472 0.01155472 418s [103] 0.01056820 0.01056820 0.01056820 0.00000000 0.01155472 0.00000000 418s [109] 0.01056820 0.01056820 0.01155472 0.01056820 0.00000000 0.01056820 418s 418s $se.fit 418s [1] 0.006800657 0.006800657 0.000000000 0.006800657 0.006800657 0.006800657 418s [7] 0.007368990 0.007368990 0.007368990 0.006800657 0.008598392 0.007368990 418s [13] 0.000000000 0.008598392 0.006800657 0.007368990 0.007368990 0.000000000 418s [19] 0.006800657 0.007779856 0.007779856 0.007368990 0.000000000 0.006800657 418s [25] 0.007368990 0.007368990 0.006800657 0.000000000 0.000000000 0.006800657 418s [31] 0.007368990 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 418s [37] 0.006800657 0.007779856 0.000000000 0.006800657 0.008598392 0.006800657 418s [43] 0.007368990 0.007368990 0.006800657 0.006800657 0.006800657 0.000000000 418s [49] 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 0.008598392 418s [55] 0.000000000 0.007368990 0.006800657 0.007368990 0.008598392 0.008598392 418s [61] 0.007368990 0.008598392 0.007368990 0.006800657 0.007779856 0.006800657 418s [67] 0.007368990 0.007368990 0.008598392 0.007368990 0.000000000 0.006800657 418s [73] 0.008598392 0.006800657 0.006800657 0.007368990 0.000000000 0.000000000 418s [79] 0.006800657 0.000000000 0.000000000 0.000000000 0.006800657 0.006800657 418s [85] 0.007368990 0.007368990 0.006800657 0.007368990 0.006800657 0.006800657 418s [91] 0.007779856 0.006800657 0.007779856 0.007368990 0.000000000 0.006800657 418s [97] 0.006800657 0.007368990 0.006800657 0.000000000 0.006800657 0.006800657 418s [103] 0.007368990 0.007368990 0.007368990 0.000000000 0.006800657 0.000000000 418s [109] 0.007368990 0.007368990 0.006800657 0.007368990 0.000000000 0.007368990 418s 418s $fit 418s [1] -0.5714146 -0.5714146 -0.5829694 -0.5714146 -0.5714146 -0.5714146 418s [7] -0.5724012 -0.5724012 -0.5724012 -0.5714146 -0.5705763 -0.5724012 418s [13] -0.5829694 -0.5705763 -0.5714146 -0.5724012 -0.5724012 -0.5829694 418s [19] -0.5714146 -0.5708485 -0.5708485 -0.5724012 -0.5829694 -0.5714146 418s [25] -0.5724012 -0.5724012 -0.5714146 -0.5829694 -0.5829694 -0.5714146 418s [31] -0.5724012 -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 418s [37] -0.5714146 -0.5708485 -0.5829694 -0.5714146 -0.5705763 -0.5714146 418s [43] -0.5724012 -0.5724012 -0.5714146 -0.5714146 -0.5714146 -0.5829694 418s [49] -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 -0.5705763 418s [55] -0.5829694 -0.5724012 -0.5714146 -0.5724012 -0.5705763 -0.5705763 418s [61] -0.5724012 -0.5705763 -0.5724012 -0.5714146 -0.5708485 -0.5714146 418s [67] -0.5724012 -0.5724012 -0.5705763 -0.5724012 -0.5829694 -0.5714146 418s [73] -0.5705763 -0.5714146 -0.5714146 -0.5724012 -0.5829694 -0.5829694 418s [79] -0.5714146 -0.5829694 -0.5829694 -0.5829694 -0.5714146 -0.5714146 418s [85] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5714146 -0.5714146 418s [91] -0.5708485 -0.5714146 -0.5708485 -0.5724012 -0.5829694 -0.5714146 418s [97] -0.5714146 -0.5724012 -0.5714146 -0.5829694 -0.5714146 -0.5714146 418s [103] -0.5724012 -0.5724012 -0.5724012 -0.5829694 -0.5714146 -0.5829694 418s [109] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5829694 -0.5724012 418s 418s $se.fit 418s [1] 0.003169353 0.003169353 0.005999821 0.003169353 0.003169353 0.003169353 418s [7] 0.004290400 0.004290400 0.004290400 0.003169353 0.006190654 0.004290400 418s [13] 0.005999821 0.006190654 0.003169353 0.004290400 0.004290400 0.005999821 418s [19] 0.003169353 0.004963663 0.004963663 0.004290400 0.005999821 0.003169353 418s [25] 0.004290400 0.004290400 0.003169353 0.005999821 0.005999821 0.003169353 418s [31] 0.004290400 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 418s [37] 0.003169353 0.004963663 0.005999821 0.003169353 0.006190654 0.003169353 418s [43] 0.004290400 0.004290400 0.003169353 0.003169353 0.003169353 0.005999821 418s [49] 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 0.006190654 418s [55] 0.005999821 0.004290400 0.003169353 0.004290400 0.006190654 0.006190654 418s [61] 0.004290400 0.006190654 0.004290400 0.003169353 0.004963663 0.003169353 418s [67] 0.004290400 0.004290400 0.006190654 0.004290400 0.005999821 0.003169353 418s [73] 0.006190654 0.003169353 0.003169353 0.004290400 0.005999821 0.005999821 418s [79] 0.003169353 0.005999821 0.005999821 0.005999821 0.003169353 0.003169353 418s [85] 0.004290400 0.004290400 0.003169353 0.004290400 0.003169353 0.003169353 418s [91] 0.004963663 0.003169353 0.004963663 0.004290400 0.005999821 0.003169353 418s [97] 0.003169353 0.004290400 0.003169353 0.005999821 0.003169353 0.003169353 418s [103] 0.004290400 0.004290400 0.004290400 0.005999821 0.003169353 0.005999821 418s [109] 0.004290400 0.004290400 0.003169353 0.004290400 0.005999821 0.004290400 418s 418s [1] 126.5178 418s [1] -481.376 418s [1] -481.378 418s Dose Response Model 418s 418s Model: emax 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -0.07408 -0.01641 -0.00232 0.01807 0.07476 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -5.81e-01 8.97e-03 418s eMax 2.93e-02 9.13e-02 418s ed50 9.03e+02 5.00e+03 418s age -1.22e-04 1.06e-04 418s centergreen 1.07e-02 8.31e-03 418s centerred 9.27e-03 7.73e-03 418s centersilver 1.22e-03 8.91e-03 418s centeryellow -4.65e-03 8.50e-03 418s 418s Residual standard error: 0.0281 418s Degrees of freedom: 106 418s 418s Formula: y ~ cbind(XX, emax(x, 0, 1, ed50)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s ed50 1.111e+03 6.451e+03 0.172 0.864 418s .lin.(Intercept) -5.813e-01 8.970e-03 -64.810 <2e-16 *** 418s .lin.centergreen 1.071e-02 8.309e-03 1.288 0.200 418s .lin.centerred 9.301e-03 7.726e-03 1.204 0.231 418s .lin.centersilver 1.196e-03 8.915e-03 0.134 0.894 418s .lin.centeryellow -4.665e-03 8.497e-03 -0.549 0.584 418s .lin.age -1.213e-04 1.057e-04 -1.148 0.254 418s .lin7 3.300e-02 1.170e-01 0.282 0.778 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.02808 on 106 degrees of freedom 418s 418s Number of iterations to convergence: 9 418s Achieved convergence tolerance: 7.042e-06 418s 418s e0 eMax ed50 age 418s e0 8.046543e-05 -3.844545e-05 2.355425e+00 -4.980066e-07 418s eMax -3.844545e-05 8.342573e-03 4.493061e+02 1.107091e-06 418s ed50 2.355425e+00 4.493061e+02 2.497229e+07 6.444381e-02 418s age -4.980066e-07 1.107091e-06 6.444381e-02 1.116195e-08 418s centergreen -1.978501e-05 6.446464e-05 4.524614e+00 -8.645567e-08 418s centerred -3.432079e-05 7.922237e-05 3.670388e+00 1.157010e-08 418s centersilver -1.753629e-05 -7.656779e-05 -3.796015e+00 -2.309374e-07 418s centeryellow -3.332560e-05 -5.044361e-05 -2.141277e+00 1.346886e-07 418s centergreen centerred centersilver centeryellow 418s e0 -1.978501e-05 -3.432079e-05 -1.753629e-05 -3.332560e-05 418s eMax 6.446464e-05 7.922237e-05 -7.656779e-05 -5.044361e-05 418s ed50 4.524614e+00 3.670388e+00 -3.796015e+00 -2.141277e+00 418s age -8.645567e-08 1.157010e-08 -2.309374e-07 1.346886e-07 418s centergreen 6.902160e-05 3.007695e-05 3.223410e-05 2.943878e-05 418s centerred 3.007695e-05 5.968790e-05 2.924362e-05 2.945739e-05 418s centersilver 3.223410e-05 2.924362e-05 7.947639e-05 2.823145e-05 418s centeryellow 2.943878e-05 2.945739e-05 2.823145e-05 7.219729e-05 418s ed50 .lin.(Intercept) .lin.centergreen 418s ed50 4.162110e+07 3.618133e+00 6.072528e+00 418s .lin.(Intercept) 3.618133e+00 8.045192e-05 -1.978784e-05 418s .lin.centergreen 6.072528e+00 -1.978784e-05 6.904772e-05 418s .lin.centerred 4.627133e+00 -3.432899e-05 3.008663e-05 418s .lin.centersilver -4.847154e+00 -1.752828e-05 3.222029e-05 418s .lin.centeryellow -2.727240e+00 -3.332482e-05 2.942341e-05 418s .lin.age 8.505296e-02 -4.980346e-07 -8.605363e-08 418s .lin7 7.456213e+02 -2.614221e-05 9.001669e-05 418s .lin.centerred .lin.centersilver .lin.centeryellow 418s ed50 4.627133e+00 -4.847154e+00 -2.727240e+00 418s .lin.(Intercept) -3.432899e-05 -1.752828e-05 -3.332482e-05 418s .lin.centergreen 3.008663e-05 3.222029e-05 2.942341e-05 418s .lin.centerred 5.968601e-05 2.924192e-05 2.945040e-05 418s .lin.centersilver 2.924192e-05 7.947836e-05 2.823890e-05 418s .lin.centeryellow 2.945040e-05 2.823890e-05 7.220391e-05 418s .lin.age 1.172543e-08 -2.311322e-07 1.344697e-07 418s .lin7 9.802604e-05 -9.643580e-05 -6.245218e-05 418s .lin.age .lin7 418s ed50 8.505296e-02 7.456213e+02 418s .lin.(Intercept) -4.980346e-07 -2.614221e-05 418s .lin.centergreen -8.605363e-08 9.001669e-05 418s .lin.centerred 1.172543e-08 9.802604e-05 418s .lin.centersilver -2.311322e-07 -9.643580e-05 418s .lin.centeryellow 1.344697e-07 -6.245218e-05 418s .lin.age 1.116761e-08 1.469361e-06 418s .lin7 1.469361e-06 1.368628e-02 418s $fit 418s [1] 0.000000000 0.002916944 418s 418s $se.fit 418s [1] 0.000000 0.005795 418s 418s $fit 418s [1] -0.5861913 -0.5832744 418s 418s $se.fit 418s [1] 0.008937545 0.009550033 418s 418s [1] 186.1323 418s [1] 2049.321 418s [1] 2049.321 418s Dose Response Model 418s 418s Model: sigEmax 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -13.6383 -2.8339 0.0791 3.0983 10.5294 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -10.92 0.555 418s eMax 17.17 3.430 418s ed50 379.22 148.679 418s h 1.38 0.349 418s 418s Residual standard error: 4.37 418s Degrees of freedom: 349 418s 418s Formula: y ~ sigEmax(x, e0, emax, ed50, h) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s e0 -10.9166 0.5552 -19.664 < 2e-16 *** 418s emax 17.1659 3.4296 5.005 8.87e-07 *** 418s ed50 379.2177 148.6773 2.551 0.0112 * 418s h 1.3754 0.3490 3.941 9.81e-05 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 4.372 on 349 degrees of freedom 418s 418s Number of iterations to convergence: 4 418s Achieved convergence tolerance: 7.003e-07 418s 418s e0 eMax ed50 h 418s e0 0.30821303 -0.518459 6.111486 0.06026433 418s eMax -0.51845901 11.762554 468.796909 -1.10430572 418s ed50 6.11148598 468.796909 22105.398796 -40.29692932 418s h 0.06026433 -1.104306 -40.296929 0.12181039 418s e0 emax ed50 h 418s e0 0.30821303 -0.5184565 6.111572 0.06026446 418s emax -0.51845645 11.7623445 468.787220 -1.10429855 418s ed50 6.11157250 468.7872203 22104.945028 -40.29652906 418s h 0.06026446 -1.1042985 -40.296529 0.12181099 418s $fit 418s [1] 12.497935 12.497935 13.842361 2.869998 13.842361 13.842361 0.000000 418s [8] 0.000000 13.842361 2.869998 12.497935 12.497935 11.114421 12.497935 418s [15] 12.497935 12.497935 12.497935 12.497935 0.000000 12.497935 12.497935 418s [22] 0.000000 13.842361 13.842361 0.000000 0.000000 2.869998 12.497935 418s [29] 2.869998 2.869998 13.842361 0.000000 11.114421 12.497935 0.000000 418s [36] 13.842361 13.842361 12.497935 13.842361 2.869998 12.497935 12.497935 418s [43] 12.497935 2.869998 12.497935 12.497935 11.114421 12.497935 13.842361 418s [50] 13.842361 12.497935 0.000000 12.497935 12.497935 0.000000 12.497935 418s [57] 0.000000 13.842361 12.497935 2.869998 12.497935 13.842361 12.497935 418s [64] 13.842361 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 418s [71] 12.497935 2.869998 12.497935 12.497935 0.000000 13.842361 0.000000 418s [78] 13.842361 12.497935 12.497935 12.497935 12.497935 13.842361 2.869998 418s [85] 12.497935 12.497935 12.497935 0.000000 0.000000 0.000000 0.000000 418s [92] 2.869998 12.497935 12.497935 2.869998 12.497935 12.497935 2.869998 418s [99] 12.497935 0.000000 12.497935 0.000000 2.869998 2.869998 2.869998 418s [106] 12.497935 13.842361 12.497935 2.869998 0.000000 13.842361 2.869998 418s [113] 12.497935 0.000000 12.497935 0.000000 13.842361 12.497935 0.000000 418s [120] 12.497935 11.114421 13.842361 12.497935 12.497935 0.000000 12.497935 418s [127] 2.869998 13.842361 12.497935 13.842361 12.497935 2.869998 12.497935 418s [134] 12.497935 12.497935 12.497935 12.497935 13.842361 13.842361 0.000000 418s [141] 11.114421 12.497935 0.000000 12.497935 13.842361 12.497935 11.114421 418s [148] 12.497935 0.000000 0.000000 2.869998 13.842361 0.000000 2.869998 418s [155] 13.842361 2.869998 11.114421 11.114421 12.497935 0.000000 12.497935 418s [162] 12.497935 2.869998 2.869998 12.497935 12.497935 12.497935 12.497935 418s [169] 2.869998 11.114421 0.000000 13.842361 12.497935 11.114421 12.497935 418s [176] 13.842361 13.842361 12.497935 12.497935 12.497935 12.497935 12.497935 418s [183] 2.869998 13.842361 0.000000 12.497935 12.497935 12.497935 2.869998 418s [190] 13.842361 12.497935 13.842361 2.869998 13.842361 12.497935 12.497935 418s [197] 12.497935 0.000000 11.114421 2.869998 12.497935 2.869998 12.497935 418s [204] 0.000000 12.497935 13.842361 12.497935 13.842361 12.497935 2.869998 418s [211] 2.869998 12.497935 13.842361 13.842361 2.869998 0.000000 13.842361 418s [218] 12.497935 12.497935 0.000000 13.842361 12.497935 12.497935 0.000000 418s [225] 13.842361 11.114421 12.497935 2.869998 12.497935 0.000000 12.497935 418s [232] 12.497935 13.842361 0.000000 12.497935 12.497935 13.842361 0.000000 418s [239] 13.842361 13.842361 12.497935 13.842361 0.000000 2.869998 12.497935 418s [246] 13.842361 12.497935 12.497935 13.842361 2.869998 0.000000 0.000000 418s [253] 11.114421 2.869998 12.497935 2.869998 13.842361 0.000000 12.497935 418s [260] 12.497935 12.497935 12.497935 11.114421 0.000000 0.000000 0.000000 418s [267] 0.000000 0.000000 0.000000 12.497935 13.842361 13.842361 2.869998 418s [274] 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 13.842361 418s [281] 12.497935 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 418s [288] 11.114421 0.000000 12.497935 12.497935 0.000000 2.869998 12.497935 418s [295] 0.000000 0.000000 13.842361 0.000000 12.497935 13.842361 12.497935 418s [302] 12.497935 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 418s [309] 11.114421 2.869998 2.869998 0.000000 13.842361 0.000000 12.497935 418s [316] 2.869998 13.842361 0.000000 13.842361 11.114421 12.497935 0.000000 418s [323] 12.497935 12.497935 0.000000 13.842361 13.842361 13.842361 13.842361 418s [330] 11.114421 2.869998 0.000000 12.497935 0.000000 12.497935 13.842361 418s [337] 12.497935 12.497935 12.497935 12.497935 12.497935 13.842361 12.497935 418s [344] 2.869998 13.842361 13.842361 2.869998 11.114421 2.869998 12.497935 418s [351] 12.497935 12.497935 13.842361 418s 418s $se.fit 418s [1] 0.6365415 0.6365415 0.7457881 0.8126372 0.7457881 0.7457881 0.0000000 418s [8] 0.0000000 0.7457881 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 418s [15] 0.6365415 0.6365415 0.6365415 0.6365415 0.0000000 0.6365415 0.6365415 418s [22] 0.0000000 0.7457881 0.7457881 0.0000000 0.0000000 0.8126372 0.6365415 418s [29] 0.8126372 0.8126372 0.7457881 0.0000000 0.8003756 0.6365415 0.0000000 418s [36] 0.7457881 0.7457881 0.6365415 0.7457881 0.8126372 0.6365415 0.6365415 418s [43] 0.6365415 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 0.7457881 418s [50] 0.7457881 0.6365415 0.0000000 0.6365415 0.6365415 0.0000000 0.6365415 418s [57] 0.0000000 0.7457881 0.6365415 0.8126372 0.6365415 0.7457881 0.6365415 418s [64] 0.7457881 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 418s [71] 0.6365415 0.8126372 0.6365415 0.6365415 0.0000000 0.7457881 0.0000000 418s [78] 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.8126372 418s [85] 0.6365415 0.6365415 0.6365415 0.0000000 0.0000000 0.0000000 0.0000000 418s [92] 0.8126372 0.6365415 0.6365415 0.8126372 0.6365415 0.6365415 0.8126372 418s [99] 0.6365415 0.0000000 0.6365415 0.0000000 0.8126372 0.8126372 0.8126372 418s [106] 0.6365415 0.7457881 0.6365415 0.8126372 0.0000000 0.7457881 0.8126372 418s [113] 0.6365415 0.0000000 0.6365415 0.0000000 0.7457881 0.6365415 0.0000000 418s [120] 0.6365415 0.8003756 0.7457881 0.6365415 0.6365415 0.0000000 0.6365415 418s [127] 0.8126372 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 0.6365415 418s [134] 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.7457881 0.0000000 418s [141] 0.8003756 0.6365415 0.0000000 0.6365415 0.7457881 0.6365415 0.8003756 418s [148] 0.6365415 0.0000000 0.0000000 0.8126372 0.7457881 0.0000000 0.8126372 418s [155] 0.7457881 0.8126372 0.8003756 0.8003756 0.6365415 0.0000000 0.6365415 418s [162] 0.6365415 0.8126372 0.8126372 0.6365415 0.6365415 0.6365415 0.6365415 418s [169] 0.8126372 0.8003756 0.0000000 0.7457881 0.6365415 0.8003756 0.6365415 418s [176] 0.7457881 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 418s [183] 0.8126372 0.7457881 0.0000000 0.6365415 0.6365415 0.6365415 0.8126372 418s [190] 0.7457881 0.6365415 0.7457881 0.8126372 0.7457881 0.6365415 0.6365415 418s [197] 0.6365415 0.0000000 0.8003756 0.8126372 0.6365415 0.8126372 0.6365415 418s [204] 0.0000000 0.6365415 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 418s [211] 0.8126372 0.6365415 0.7457881 0.7457881 0.8126372 0.0000000 0.7457881 418s [218] 0.6365415 0.6365415 0.0000000 0.7457881 0.6365415 0.6365415 0.0000000 418s [225] 0.7457881 0.8003756 0.6365415 0.8126372 0.6365415 0.0000000 0.6365415 418s [232] 0.6365415 0.7457881 0.0000000 0.6365415 0.6365415 0.7457881 0.0000000 418s [239] 0.7457881 0.7457881 0.6365415 0.7457881 0.0000000 0.8126372 0.6365415 418s [246] 0.7457881 0.6365415 0.6365415 0.7457881 0.8126372 0.0000000 0.0000000 418s [253] 0.8003756 0.8126372 0.6365415 0.8126372 0.7457881 0.0000000 0.6365415 418s [260] 0.6365415 0.6365415 0.6365415 0.8003756 0.0000000 0.0000000 0.0000000 418s [267] 0.0000000 0.0000000 0.0000000 0.6365415 0.7457881 0.7457881 0.8126372 418s [274] 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 0.7457881 418s [281] 0.6365415 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 418s [288] 0.8003756 0.0000000 0.6365415 0.6365415 0.0000000 0.8126372 0.6365415 418s [295] 0.0000000 0.0000000 0.7457881 0.0000000 0.6365415 0.7457881 0.6365415 418s [302] 0.6365415 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 418s [309] 0.8003756 0.8126372 0.8126372 0.0000000 0.7457881 0.0000000 0.6365415 418s [316] 0.8126372 0.7457881 0.0000000 0.7457881 0.8003756 0.6365415 0.0000000 418s [323] 0.6365415 0.6365415 0.0000000 0.7457881 0.7457881 0.7457881 0.7457881 418s [330] 0.8003756 0.8126372 0.0000000 0.6365415 0.0000000 0.6365415 0.7457881 418s [337] 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.6365415 418s [344] 0.8126372 0.7457881 0.7457881 0.8126372 0.8003756 0.8126372 0.6365415 418s [351] 0.6365415 0.6365415 0.7457881 418s 418s $fit 418s [1] 1.5813420 1.5813420 2.9257679 -8.0465953 2.9257679 2.9257679 418s [7] -10.9165932 -10.9165932 2.9257679 -8.0465953 1.5813420 1.5813420 418s [13] 0.1978277 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 418s [19] -10.9165932 1.5813420 1.5813420 -10.9165932 2.9257679 2.9257679 418s [25] -10.9165932 -10.9165932 -8.0465953 1.5813420 -8.0465953 -8.0465953 418s [31] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 2.9257679 418s [37] 2.9257679 1.5813420 2.9257679 -8.0465953 1.5813420 1.5813420 418s [43] 1.5813420 -8.0465953 1.5813420 1.5813420 0.1978277 1.5813420 418s [49] 2.9257679 2.9257679 1.5813420 -10.9165932 1.5813420 1.5813420 418s [55] -10.9165932 1.5813420 -10.9165932 2.9257679 1.5813420 -8.0465953 418s [61] 1.5813420 2.9257679 1.5813420 2.9257679 2.9257679 1.5813420 418s [67] 1.5813420 -8.0465953 1.5813420 -8.0465953 1.5813420 -8.0465953 418s [73] 1.5813420 1.5813420 -10.9165932 2.9257679 -10.9165932 2.9257679 418s [79] 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 -8.0465953 418s [85] 1.5813420 1.5813420 1.5813420 -10.9165932 -10.9165932 -10.9165932 418s [91] -10.9165932 -8.0465953 1.5813420 1.5813420 -8.0465953 1.5813420 418s [97] 1.5813420 -8.0465953 1.5813420 -10.9165932 1.5813420 -10.9165932 418s [103] -8.0465953 -8.0465953 -8.0465953 1.5813420 2.9257679 1.5813420 418s [109] -8.0465953 -10.9165932 2.9257679 -8.0465953 1.5813420 -10.9165932 418s [115] 1.5813420 -10.9165932 2.9257679 1.5813420 -10.9165932 1.5813420 418s [121] 0.1978277 2.9257679 1.5813420 1.5813420 -10.9165932 1.5813420 418s [127] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 418s [133] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 418s [139] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 1.5813420 418s [145] 2.9257679 1.5813420 0.1978277 1.5813420 -10.9165932 -10.9165932 418s [151] -8.0465953 2.9257679 -10.9165932 -8.0465953 2.9257679 -8.0465953 418s [157] 0.1978277 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 418s [163] -8.0465953 -8.0465953 1.5813420 1.5813420 1.5813420 1.5813420 418s [169] -8.0465953 0.1978277 -10.9165932 2.9257679 1.5813420 0.1978277 418s [175] 1.5813420 2.9257679 2.9257679 1.5813420 1.5813420 1.5813420 418s [181] 1.5813420 1.5813420 -8.0465953 2.9257679 -10.9165932 1.5813420 418s [187] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 2.9257679 418s [193] -8.0465953 2.9257679 1.5813420 1.5813420 1.5813420 -10.9165932 418s [199] 0.1978277 -8.0465953 1.5813420 -8.0465953 1.5813420 -10.9165932 418s [205] 1.5813420 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 418s [211] -8.0465953 1.5813420 2.9257679 2.9257679 -8.0465953 -10.9165932 418s [217] 2.9257679 1.5813420 1.5813420 -10.9165932 2.9257679 1.5813420 418s [223] 1.5813420 -10.9165932 2.9257679 0.1978277 1.5813420 -8.0465953 418s [229] 1.5813420 -10.9165932 1.5813420 1.5813420 2.9257679 -10.9165932 418s [235] 1.5813420 1.5813420 2.9257679 -10.9165932 2.9257679 2.9257679 418s [241] 1.5813420 2.9257679 -10.9165932 -8.0465953 1.5813420 2.9257679 418s [247] 1.5813420 1.5813420 2.9257679 -8.0465953 -10.9165932 -10.9165932 418s [253] 0.1978277 -8.0465953 1.5813420 -8.0465953 2.9257679 -10.9165932 418s [259] 1.5813420 1.5813420 1.5813420 1.5813420 0.1978277 -10.9165932 418s [265] -10.9165932 -10.9165932 -10.9165932 -10.9165932 -10.9165932 1.5813420 418s [271] 2.9257679 2.9257679 -8.0465953 1.5813420 1.5813420 1.5813420 418s [277] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 1.5813420 418s [283] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 0.1978277 418s [289] -10.9165932 1.5813420 1.5813420 -10.9165932 -8.0465953 1.5813420 418s [295] -10.9165932 -10.9165932 2.9257679 -10.9165932 1.5813420 2.9257679 418s [301] 1.5813420 1.5813420 2.9257679 1.5813420 1.5813420 -8.0465953 418s [307] 1.5813420 -8.0465953 0.1978277 -8.0465953 -8.0465953 -10.9165932 418s [313] 2.9257679 -10.9165932 1.5813420 -8.0465953 2.9257679 -10.9165932 418s [319] 2.9257679 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 418s [325] -10.9165932 2.9257679 2.9257679 2.9257679 2.9257679 0.1978277 418s [331] -8.0465953 -10.9165932 1.5813420 -10.9165932 1.5813420 2.9257679 418s [337] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 418s [343] 1.5813420 -8.0465953 2.9257679 2.9257679 -8.0465953 0.1978277 418s [349] -8.0465953 1.5813420 1.5813420 1.5813420 2.9257679 418s 418s $se.fit 418s [1] 0.3179632 0.3179632 0.4944930 0.5940988 0.4944930 0.4944930 0.5551694 418s [8] 0.5551694 0.4944930 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 418s [15] 0.3179632 0.3179632 0.3179632 0.3179632 0.5551694 0.3179632 0.3179632 418s [22] 0.5551694 0.4944930 0.4944930 0.5551694 0.5551694 0.5940988 0.3179632 418s [29] 0.5940988 0.5940988 0.4944930 0.5551694 0.5590023 0.3179632 0.5551694 418s [36] 0.4944930 0.4944930 0.3179632 0.4944930 0.5940988 0.3179632 0.3179632 418s [43] 0.3179632 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 0.4944930 418s [50] 0.4944930 0.3179632 0.5551694 0.3179632 0.3179632 0.5551694 0.3179632 418s [57] 0.5551694 0.4944930 0.3179632 0.5940988 0.3179632 0.4944930 0.3179632 418s [64] 0.4944930 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 418s [71] 0.3179632 0.5940988 0.3179632 0.3179632 0.5551694 0.4944930 0.5551694 418s [78] 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.5940988 418s [85] 0.3179632 0.3179632 0.3179632 0.5551694 0.5551694 0.5551694 0.5551694 418s [92] 0.5940988 0.3179632 0.3179632 0.5940988 0.3179632 0.3179632 0.5940988 418s [99] 0.3179632 0.5551694 0.3179632 0.5551694 0.5940988 0.5940988 0.5940988 418s [106] 0.3179632 0.4944930 0.3179632 0.5940988 0.5551694 0.4944930 0.5940988 418s [113] 0.3179632 0.5551694 0.3179632 0.5551694 0.4944930 0.3179632 0.5551694 418s [120] 0.3179632 0.5590023 0.4944930 0.3179632 0.3179632 0.5551694 0.3179632 418s [127] 0.5940988 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 0.3179632 418s [134] 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.4944930 0.5551694 418s [141] 0.5590023 0.3179632 0.5551694 0.3179632 0.4944930 0.3179632 0.5590023 418s [148] 0.3179632 0.5551694 0.5551694 0.5940988 0.4944930 0.5551694 0.5940988 418s [155] 0.4944930 0.5940988 0.5590023 0.5590023 0.3179632 0.5551694 0.3179632 418s [162] 0.3179632 0.5940988 0.5940988 0.3179632 0.3179632 0.3179632 0.3179632 418s [169] 0.5940988 0.5590023 0.5551694 0.4944930 0.3179632 0.5590023 0.3179632 418s [176] 0.4944930 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 418s [183] 0.5940988 0.4944930 0.5551694 0.3179632 0.3179632 0.3179632 0.5940988 418s [190] 0.4944930 0.3179632 0.4944930 0.5940988 0.4944930 0.3179632 0.3179632 418s [197] 0.3179632 0.5551694 0.5590023 0.5940988 0.3179632 0.5940988 0.3179632 418s [204] 0.5551694 0.3179632 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 418s [211] 0.5940988 0.3179632 0.4944930 0.4944930 0.5940988 0.5551694 0.4944930 418s [218] 0.3179632 0.3179632 0.5551694 0.4944930 0.3179632 0.3179632 0.5551694 418s [225] 0.4944930 0.5590023 0.3179632 0.5940988 0.3179632 0.5551694 0.3179632 418s [232] 0.3179632 0.4944930 0.5551694 0.3179632 0.3179632 0.4944930 0.5551694 418s [239] 0.4944930 0.4944930 0.3179632 0.4944930 0.5551694 0.5940988 0.3179632 418s [246] 0.4944930 0.3179632 0.3179632 0.4944930 0.5940988 0.5551694 0.5551694 418s [253] 0.5590023 0.5940988 0.3179632 0.5940988 0.4944930 0.5551694 0.3179632 418s [260] 0.3179632 0.3179632 0.3179632 0.5590023 0.5551694 0.5551694 0.5551694 418s [267] 0.5551694 0.5551694 0.5551694 0.3179632 0.4944930 0.4944930 0.5940988 418s [274] 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 0.4944930 418s [281] 0.3179632 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 418s [288] 0.5590023 0.5551694 0.3179632 0.3179632 0.5551694 0.5940988 0.3179632 418s [295] 0.5551694 0.5551694 0.4944930 0.5551694 0.3179632 0.4944930 0.3179632 418s [302] 0.3179632 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 418s [309] 0.5590023 0.5940988 0.5940988 0.5551694 0.4944930 0.5551694 0.3179632 418s [316] 0.5940988 0.4944930 0.5551694 0.4944930 0.5590023 0.3179632 0.5551694 418s [323] 0.3179632 0.3179632 0.5551694 0.4944930 0.4944930 0.4944930 0.4944930 418s [330] 0.5590023 0.5940988 0.5551694 0.3179632 0.5551694 0.3179632 0.4944930 418s [337] 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.3179632 418s [344] 0.5940988 0.4944930 0.4944930 0.5940988 0.5590023 0.5940988 0.3179632 418s [351] 0.3179632 0.3179632 0.4944930 418s 418s [1] 50.13645 418s [1] 2052.27 418s [1] 2052.27 418s Dose Response Model 418s 418s Model: sigEmax 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -13.6642 -2.5494 -0.0589 3.1494 10.8255 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -9.3604 8.43e-01 418s eMax 18.0312 4.04e+00 418s ed50 427.8168 1.83e+02 418s h 1.3276 3.36e-01 418s age -0.0117 8.11e-03 418s centergreen -0.7488 7.57e-01 418s centerred -0.8859 7.12e-01 418s centersilver -1.4084 7.52e-01 418s centeryellow -1.4438 7.33e-01 418s 418s Residual standard error: 4.36 418s Degrees of freedom: 344 418s 418s Formula: y ~ cbind(XX, sigEmax(x, 0, 1, ed50, h)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s ed50 427.813485 182.738235 2.341 0.0198 * 418s h 1.327626 0.335875 3.953 9.38e-05 *** 418s .lin.(Intercept) -9.360422 0.842795 -11.106 < 2e-16 *** 418s .lin.centergreen -0.748766 0.757412 -0.989 0.3236 418s .lin.centerred -0.885871 0.711909 -1.244 0.2142 418s .lin.centersilver -1.408359 0.752071 -1.873 0.0620 . 418s .lin.centeryellow -1.443811 0.733469 -1.968 0.0498 * 418s .lin.age -0.011703 0.008114 -1.442 0.1501 418s .lin7 18.031101 4.042408 4.460 1.11e-05 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 4.36 on 344 degrees of freedom 418s 418s Number of iterations to convergence: 4 418s Achieved convergence tolerance: 7.011e-06 418s 418s e0 eMax ed50 h 418s e0 0.710302651 -4.248050e-01 12.9547646 5.611113e-02 418s eMax -0.424805031 1.634158e+01 694.3472381 -1.241172e+00 418s ed50 12.954764636 6.943472e+02 33394.5385877 -4.820462e+01 418s h 0.056111134 -1.241172e+00 -48.2046174 1.128111e-01 418s age -0.003282055 -7.347999e-04 -0.0251683 3.613375e-05 418s centergreen -0.239527553 2.751352e-02 1.4126289 -4.650674e-03 418s centerred -0.290825609 -1.412230e-01 -9.3345325 5.133219e-03 418s centersilver -0.296694203 -2.684223e-01 -15.5401130 1.239080e-02 418s centeryellow -0.294618448 -1.827692e-01 -11.6914478 8.045886e-03 418s age centergreen centerred centersilver 418s e0 -3.282055e-03 -0.2395275534 -2.908256e-01 -2.966942e-01 418s eMax -7.347999e-04 0.0275135152 -1.412230e-01 -2.684223e-01 418s ed50 -2.516830e-02 1.4126288554 -9.334532e+00 -1.554011e+01 418s h 3.613375e-05 -0.0046506738 5.133219e-03 1.239080e-02 418s age 6.584109e-05 -0.0004705249 3.847994e-05 1.268608e-04 418s centergreen -4.705249e-04 0.5736725480 2.674552e-01 2.669211e-01 418s centerred 3.847994e-05 0.2674552437 5.068148e-01 2.741110e-01 418s centersilver 1.268608e-04 0.2669210775 2.741110e-01 5.656114e-01 418s centeryellow 3.360823e-05 0.2672881708 2.729000e-01 2.753064e-01 418s centeryellow 418s e0 -2.946184e-01 418s eMax -1.827692e-01 418s ed50 -1.169145e+01 418s h 8.045886e-03 418s age 3.360823e-05 418s centergreen 2.672882e-01 418s centerred 2.729000e-01 418s centersilver 2.753064e-01 418s centeryellow 5.379774e-01 418s ed50 h .lin.(Intercept) .lin.centergreen 418s ed50 3.339326e+04 -4.820368e+01 12.954857951 1.4125968763 418s h -4.820368e+01 1.128119e-01 0.056111301 -0.0046506977 418s .lin.(Intercept) 1.295486e+01 5.611130e-02 0.710302646 -0.2395275479 418s .lin.centergreen 1.412597e+00 -4.650698e-03 -0.239527548 0.5736725490 418s .lin.centerred -9.334399e+00 5.133265e-03 -0.290825609 0.2674552401 418s .lin.centersilver -1.553987e+01 1.239088e-02 -0.296694200 0.2669210719 418s .lin.centeryellow -1.169127e+01 8.045945e-03 -0.294618447 0.2672881664 418s .lin.age -2.516783e-02 3.613396e-05 -0.003282055 -0.0004705249 418s .lin7 6.943216e+02 -1.241157e+00 -0.424801883 0.0275130191 418s .lin.centerred .lin.centersilver .lin.centeryellow 418s ed50 -9.334399e+00 -1.553987e+01 -1.169127e+01 418s h 5.133265e-03 1.239088e-02 8.045945e-03 418s .lin.(Intercept) -2.908256e-01 -2.966942e-01 -2.946184e-01 418s .lin.centergreen 2.674552e-01 2.669211e-01 2.672882e-01 418s .lin.centerred 5.068148e-01 2.741110e-01 2.729000e-01 418s .lin.centersilver 2.741110e-01 5.656114e-01 2.753064e-01 418s .lin.centeryellow 2.729000e-01 2.753064e-01 5.379774e-01 418s .lin.age 3.847993e-05 1.268608e-04 3.360822e-05 418s .lin7 -1.412207e-01 -2.684181e-01 -1.827663e-01 418s .lin.age .lin7 418s ed50 -2.516783e-02 6.943216e+02 418s h 3.613396e-05 -1.241157e+00 418s .lin.(Intercept) -3.282055e-03 -4.248019e-01 418s .lin.centergreen -4.705249e-04 2.751302e-02 418s .lin.centerred 3.847993e-05 -1.412207e-01 418s .lin.centersilver 1.268608e-04 -2.684181e-01 418s .lin.centeryellow 3.360822e-05 -1.827663e-01 418s .lin.age 6.584109e-05 -7.347909e-04 418s .lin7 -7.347909e-04 1.634107e+01 418s $fit 418s [1] 0.000000 2.286007 418s 418s $se.fit 418s [1] 0.0000000 0.7638951 418s 418s $fit 418s [1] -11.353936 -9.067928 418s 418s $se.fit 418s [1] 0.7291152 0.7547668 418s 418s [1] 50.56495 418s [1] 336.0966 418s [1] 336.0966 418s Dose Response Model 418s 418s Model: logistic 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -6.606 -1.402 -0.298 1.561 5.618 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -8.93 1.09 418s eMax 7.45 1.19 418s ed50 288.28 49.89 418s delta 43.71 37.57 418s 418s Residual standard error: 2.32 418s Degrees of freedom: 69 418s 418s Formula: y ~ logistic(x, e0, emax, ed50, delta) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s e0 -8.931 1.092 -8.179 9.42e-12 *** 418s emax 7.453 1.192 6.251 2.94e-08 *** 418s ed50 288.282 49.890 5.778 1.99e-07 *** 418s delta 43.709 37.566 1.164 0.249 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 2.323 on 69 degrees of freedom 418s 418s Number of iterations to convergence: 5 418s Achieved convergence tolerance: 1.919e-07 418s 418s e0 eMax ed50 delta 418s e0 1.192360 -1.220565 45.77140 -33.34815 418s eMax -1.220565 1.421491 -43.96678 35.28563 418s ed50 45.771404 -43.966775 2488.99403 -1733.71521 418s delta -33.348145 35.285633 -1733.71521 1411.22511 418s e0 emax ed50 delta 418s e0 1.192360 -1.220566 45.77135 -33.34807 418s emax -1.220566 1.421491 -43.96672 35.28556 418s ed50 45.771350 -43.966716 2488.98722 -1733.70801 418s delta -33.348072 35.285560 -1733.70801 1411.21852 418s $fit 418s [1] 0.0000000 5.6020564 7.4419763 7.4430636 5.6020564 0.3578039 7.4430636 418s [8] 0.3578039 7.4130064 7.4419763 5.6020564 5.6020564 5.6020564 5.6020564 418s [15] 5.6020564 5.6020564 7.4130064 0.3578039 0.3578039 7.4419763 0.3578039 418s [22] 7.4430636 0.3578039 7.4419763 7.4430636 0.3578039 7.4419763 7.4419763 418s [29] 5.6020564 0.0000000 7.4419763 5.6020564 7.4130064 7.4130064 7.4430636 418s [36] 0.0000000 7.4419763 7.4430636 5.6020564 5.6020564 5.6020564 7.4419763 418s [43] 5.6020564 0.3578039 7.4130064 5.6020564 7.4419763 0.3578039 5.6020564 418s [50] 0.0000000 5.6020564 7.4130064 7.4430636 5.6020564 0.3578039 7.4419763 418s [57] 7.4130064 7.4430636 7.4419763 7.4430636 0.0000000 5.6020564 5.6020564 418s [64] 5.6020564 7.4419763 5.6020564 7.4419763 7.4130064 7.4419763 5.6020564 418s [71] 5.6020564 0.3578039 5.6020564 418s 418s $se.fit 418s [1] 0.000000 1.134891 1.131632 1.137062 1.134891 1.244804 1.137062 1.244804 418s [9] 1.051179 1.131632 1.134891 1.134891 1.134891 1.134891 1.134891 1.134891 418s [17] 1.051179 1.244804 1.244804 1.131632 1.244804 1.137062 1.244804 1.131632 418s [25] 1.137062 1.244804 1.131632 1.131632 1.134891 0.000000 1.131632 1.134891 418s [33] 1.051179 1.051179 1.137062 0.000000 1.131632 1.137062 1.134891 1.134891 418s [41] 1.134891 1.131632 1.134891 1.244804 1.051179 1.134891 1.131632 1.244804 418s [49] 1.134891 0.000000 1.134891 1.051179 1.137062 1.134891 1.244804 1.131632 418s [57] 1.051179 1.137062 1.131632 1.137062 0.000000 1.134891 1.134891 1.134891 418s [65] 1.131632 1.134891 1.131632 1.051179 1.131632 1.134891 1.134891 1.244804 418s [73] 1.134891 418s 418s $fit 418s [1] -8.920547 -3.318491 -1.478571 -1.477483 -3.318491 -8.562743 -1.477483 418s [8] -8.562743 -1.507541 -1.478571 -3.318491 -3.318491 -3.318491 -3.318491 418s [15] -3.318491 -3.318491 -1.507541 -8.562743 -8.562743 -1.478571 -8.562743 418s [22] -1.477483 -8.562743 -1.478571 -1.477483 -8.562743 -1.478571 -1.478571 418s [29] -3.318491 -8.920547 -1.478571 -3.318491 -1.507541 -1.507541 -1.477483 418s [36] -8.920547 -1.478571 -1.477483 -3.318491 -3.318491 -3.318491 -1.478571 418s [43] -3.318491 -8.562743 -1.507541 -3.318491 -1.478571 -8.562743 -3.318491 418s [50] -8.920547 -3.318491 -1.507541 -1.477483 -3.318491 -8.562743 -1.478571 418s [57] -1.507541 -1.477483 -1.478571 -1.477483 -8.920547 -3.318491 -3.318491 418s [64] -3.318491 -1.478571 -3.318491 -1.478571 -1.507541 -1.478571 -3.318491 418s [71] -3.318491 -8.562743 -3.318491 418s 418s $se.fit 418s [1] 1.0345960 0.4644528 0.4144011 0.4155112 0.4644528 0.6986843 0.4155112 418s [8] 0.6986843 0.4088615 0.4144011 0.4644528 0.4644528 0.4644528 0.4644528 418s [15] 0.4644528 0.4644528 0.4088615 0.6986843 0.6986843 0.4144011 0.6986843 418s [22] 0.4155112 0.6986843 0.4144011 0.4155112 0.6986843 0.4144011 0.4144011 418s [29] 0.4644528 1.0345960 0.4144011 0.4644528 0.4088615 0.4088615 0.4155112 418s [36] 1.0345960 0.4144011 0.4155112 0.4644528 0.4644528 0.4644528 0.4144011 418s [43] 0.4644528 0.6986843 0.4088615 0.4644528 0.4144011 0.6986843 0.4644528 418s [50] 1.0345960 0.4644528 0.4088615 0.4155112 0.4644528 0.6986843 0.4144011 418s [57] 0.4088615 0.4155112 0.4144011 0.4155112 1.0345960 0.4644528 0.4644528 418s [64] 0.4644528 0.4144011 0.4644528 0.4144011 0.4088615 0.4144011 0.4644528 418s [71] 0.4644528 0.6986843 0.4644528 418s 418s [1] 174.1673 418s [1] 345.1575 418s [1] 345.1575 418s Dose Response Model 418s 418s Model: logistic 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -6.924 -1.388 -0.179 1.618 5.265 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -8.98657 1.419 418s eMax 7.65181 1.269 418s ed50 286.51988 50.767 418s delta 43.51040 36.726 418s age -0.00402 0.011 418s centergreen -0.12880 0.873 418s centerred 0.10022 0.975 418s centersilver 0.60689 0.985 418s centeryellow 0.06974 0.968 418s 418s Residual standard error: 2.4 418s Degrees of freedom: 64 418s 418s Formula: y ~ cbind(XX, logistic(x, 0, 1, ed50, delta)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s ed50 286.519964 50.768015 5.644 4.08e-07 *** 418s delta 43.510063 36.726740 1.185 0.241 418s .lin.(Intercept) -8.986562 1.418992 -6.333 2.71e-08 *** 418s .lin.centergreen -0.128797 0.873355 -0.147 0.883 418s .lin.centerred 0.100221 0.975122 0.103 0.918 418s .lin.centersilver 0.606894 0.985016 0.616 0.540 418s .lin.centeryellow 0.069737 0.968243 0.072 0.943 418s .lin.age -0.004017 0.011024 -0.364 0.717 418s .lin7 7.651799 1.268713 6.031 8.96e-08 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 2.396 on 64 degrees of freedom 418s 418s Number of iterations to convergence: 4 418s Achieved convergence tolerance: 6.662e-06 418s 418s e0 eMax ed50 delta 418s e0 2.013542598 -1.386381624 4.801326e+01 -3.320465e+01 418s eMax -1.386381624 1.609637809 -4.594280e+01 3.537786e+01 418s ed50 48.013263927 -45.942796989 2.577339e+03 -1.719550e+03 418s delta -33.204646040 35.377861787 -1.719550e+03 1.348832e+03 418s age -0.006268645 0.001147196 1.238916e-02 -1.182615e-04 418s centergreen -0.334052153 -0.153718220 1.779756e+00 -1.607538e+00 418s centerred -0.399667176 -0.068891593 -2.561521e+00 7.131922e-01 418s centersilver -0.538856175 0.113916607 8.446386e-02 -1.524166e+00 418s centeryellow -0.463856043 -0.044371048 -3.153773e+00 1.284203e+00 418s age centergreen centerred centersilver 418s e0 -0.0062686454 -0.3340521534 -0.399667176 -0.5388561747 418s eMax 0.0011471962 -0.1537182198 -0.068891593 0.1139166068 418s ed50 0.0123891577 1.7797560821 -2.561520564 0.0844638637 418s delta -0.0001182615 -1.6075377841 0.713192229 -1.5241663474 418s age 0.0001215321 -0.0007558322 -0.001348561 -0.0006628626 418s centergreen -0.0007558322 0.7627491953 0.499187248 0.4609636575 418s centerred -0.0013485609 0.4991872483 0.950863865 0.4738663247 418s centersilver -0.0006628626 0.4609636575 0.473866325 0.9702565708 418s centeryellow -0.0003700776 0.4923423826 0.498378928 0.4677967285 418s centeryellow 418s e0 -0.4638560434 418s eMax -0.0443710477 418s ed50 -3.1537729813 418s delta 1.2842028647 418s age -0.0003700776 418s centergreen 0.4923423826 418s centerred 0.4983789279 418s centersilver 0.4677967285 418s centeryellow 0.9374951281 418s ed50 delta .lin.(Intercept) .lin.centergreen 418s ed50 2.577391e+03 -1.719586e+03 48.013677315 1.7797792567 418s delta -1.719586e+03 1.348853e+03 -33.204888391 -1.6075530130 418s .lin.(Intercept) 4.801368e+01 -3.320489e+01 2.013538898 -0.3340522698 418s .lin.centergreen 1.779779e+00 -1.607553e+00 -0.334052270 0.7627491914 418s .lin.centerred -2.561536e+00 7.132043e-01 -0.399667186 0.4991872438 418s .lin.centersilver 8.448346e-02 -1.524166e+00 -0.538856201 0.4609636569 418s .lin.centeryellow -3.153788e+00 1.284211e+00 -0.463855836 0.4923423906 418s .lin.age 1.238908e-02 -1.181843e-04 -0.006268647 -0.0007558323 418s .lin7 -4.594321e+01 3.537808e+01 -1.386377238 -0.1537180607 418s .lin.centerred .lin.centersilver .lin.centeryellow 418s ed50 -2.561536182 0.0844834632 -3.1537877329 418s delta 0.713204316 -1.5241655404 1.2842105849 418s .lin.(Intercept) -0.399667186 -0.5388562012 -0.4638558362 418s .lin.centergreen 0.499187244 0.4609636569 0.4923423906 418s .lin.centerred 0.950863862 0.4738663194 0.4983789309 418s .lin.centersilver 0.473866319 0.9702565797 0.4677967416 418s .lin.centeryellow 0.498378931 0.4677967416 0.9374951276 418s .lin.age -0.001348561 -0.0006628628 -0.0003700776 418s .lin7 -0.068891565 0.1139166786 -0.0443712888 418s .lin.age .lin7 418s ed50 0.0123890830 -45.943205630 418s delta -0.0001181843 35.378080025 418s .lin.(Intercept) -0.0062686472 -1.386377238 418s .lin.centergreen -0.0007558323 -0.153718061 418s .lin.centerred -0.0013485609 -0.068891565 418s .lin.centersilver -0.0006628628 0.113916679 418s .lin.centeryellow -0.0003700776 -0.044371289 418s .lin.age 0.0001215321 0.001147198 418s .lin7 0.0011471983 1.609632528 418s $fit 418s [1] 0.00000000 0.09322688 418s 418s $se.fit 418s [1] 0.0000000 0.4246053 418s 418s $fit 418s [1] -8.389208 -8.295981 418s 418s $se.fit 418s [1] 1.306647 1.060317 418s 418s [1] 46.37307 418s [1] -1501.193 418s [1] -1501.193 418s Dose Response Model 418s 418s Model: exponential 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -2.70e-01 -5.95e-02 7.18e-05 5.87e-02 2.44e-01 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -0.466 6.03e-03 418s e1 0.125 9.54e-02 418s delta 972.943 4.86e+02 418s 418s Residual standard error: 0.0841 418s Degrees of freedom: 710 418s 418s Formula: y ~ exponential(x, e0, e1, delta) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s e0 -0.466094 0.006025 -77.359 <2e-16 *** 418s e1 0.124504 0.095374 1.305 0.1922 418s delta 972.943061 485.901662 2.002 0.0456 * 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.08415 on 710 degrees of freedom 418s 418s Number of iterations to convergence: 0 418s Achieved convergence tolerance: 1.033e-08 418s 418s e0 e1 delta 418s e0 3.630153e-05 -0.0004207858 -2.060285 418s e1 -4.207858e-04 0.0090961407 46.252646 418s delta -2.060285e+00 46.2526456895 236100.427432 418s e0 e1 delta 418s e0 3.630155e-05 -0.000420786 -2.060286 418s e1 -4.207860e-04 0.009096141 46.252645 418s delta -2.060286e+00 46.252645043 236100.424914 418s $fit 418s [1] 0.00000000 0.03271671 0.00000000 0.11169230 0.01605388 0.18278309 418s [7] 0.18278309 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 418s [13] 0.11169230 0.01605388 0.18278309 0.18278309 0.18278309 0.18278309 418s [19] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.00000000 418s [25] 0.01605388 0.00000000 0.11169230 0.00000000 0.18278309 0.03271671 418s [31] 0.18278309 0.01605388 0.00000000 0.03271671 0.00000000 0.03271671 418s [37] 0.03271671 0.11169230 0.00000000 0.03271671 0.01605388 0.18278309 418s [43] 0.01605388 0.03271671 0.01605388 0.01605388 0.01605388 0.18278309 418s [49] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 418s [55] 0.03271671 0.03271671 0.01605388 0.00000000 0.11169230 0.18278309 418s [61] 0.00000000 0.18278309 0.18278309 0.03271671 0.03271671 0.01605388 418s [67] 0.00000000 0.03271671 0.18278309 0.01605388 0.03271671 0.00000000 418s [73] 0.00000000 0.01605388 0.18278309 0.01605388 0.00000000 0.01605388 418s [79] 0.01605388 0.01605388 0.18278309 0.18278309 0.00000000 0.01605388 418s [85] 0.11169230 0.11169230 0.01605388 0.18278309 0.11169230 0.03271671 418s [91] 0.03271671 0.18278309 0.01605388 0.11169230 0.03271671 0.00000000 418s [97] 0.18278309 0.00000000 0.00000000 0.01605388 0.11169230 0.00000000 418s [103] 0.11169230 0.03271671 0.11169230 0.18278309 0.01605388 0.00000000 418s [109] 0.11169230 0.01605388 0.11169230 0.00000000 0.00000000 0.01605388 418s [115] 0.11169230 0.01605388 0.11169230 0.11169230 0.18278309 0.01605388 418s [121] 0.11169230 0.18278309 0.00000000 0.03271671 0.18278309 0.01605388 418s [127] 0.01605388 0.03271671 0.03271671 0.11169230 0.11169230 0.18278309 418s [133] 0.00000000 0.00000000 0.01605388 0.01605388 0.01605388 0.01605388 418s [139] 0.01605388 0.18278309 0.18278309 0.01605388 0.00000000 0.18278309 418s [145] 0.00000000 0.01605388 0.18278309 0.03271671 0.18278309 0.01605388 418s [151] 0.00000000 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 418s [157] 0.01605388 0.01605388 0.00000000 0.11169230 0.00000000 0.00000000 418s [163] 0.01605388 0.03271671 0.03271671 0.00000000 0.11169230 0.18278309 418s [169] 0.18278309 0.01605388 0.03271671 0.03271671 0.11169230 0.01605388 418s [175] 0.01605388 0.03271671 0.03271671 0.00000000 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0.006025075 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 418s [157] 0.003835233 0.003835233 0.006025075 0.006884091 0.006025075 0.006025075 418s [163] 0.003835233 0.004212735 0.004212735 0.006025075 0.006884091 0.007313632 418s [169] 0.007313632 0.003835233 0.004212735 0.004212735 0.006884091 0.003835233 418s [175] 0.003835233 0.004212735 0.004212735 0.006025075 0.003835233 0.003835233 418s [181] 0.006884091 0.003835233 0.004212735 0.007313632 0.006884091 0.003835233 418s [187] 0.006884091 0.004212735 0.003835233 0.004212735 0.006025075 0.007313632 418s [193] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.006884091 418s [199] 0.003835233 0.006025075 0.006884091 0.006884091 0.003835233 0.004212735 418s [205] 0.006025075 0.003835233 0.006025075 0.006025075 0.003835233 0.003835233 418s [211] 0.003835233 0.004212735 0.003835233 0.004212735 0.003835233 0.007313632 418s [217] 0.003835233 0.006884091 0.003835233 0.007313632 0.006884091 0.003835233 418s [223] 0.006884091 0.007313632 0.004212735 0.007313632 0.004212735 0.006884091 418s [229] 0.006884091 0.006025075 0.003835233 0.003835233 0.006884091 0.006025075 418s [235] 0.007313632 0.004212735 0.003835233 0.006884091 0.007313632 0.007313632 418s [241] 0.003835233 0.004212735 0.006025075 0.004212735 0.007313632 0.003835233 418s [247] 0.003835233 0.004212735 0.003835233 0.006884091 0.004212735 0.004212735 418s [253] 0.006884091 0.006025075 0.006025075 0.006025075 0.003835233 0.006884091 418s [259] 0.007313632 0.003835233 0.007313632 0.003835233 0.007313632 0.004212735 418s [265] 0.003835233 0.004212735 0.003835233 0.007313632 0.007313632 0.004212735 418s [271] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.003835233 418s [277] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.004212735 418s [283] 0.007313632 0.003835233 0.006025075 0.003835233 0.003835233 0.003835233 418s [289] 0.006884091 0.004212735 0.004212735 0.003835233 0.004212735 0.003835233 418s [295] 0.004212735 0.006025075 0.006025075 0.003835233 0.006025075 0.003835233 418s [301] 0.006884091 0.006884091 0.007313632 0.006884091 0.003835233 0.003835233 418s [307] 0.003835233 0.004212735 0.004212735 0.004212735 0.003835233 0.007313632 418s [313] 0.004212735 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 418s [319] 0.004212735 0.006884091 0.004212735 0.003835233 0.003835233 0.003835233 418s [325] 0.007313632 0.006884091 0.003835233 0.004212735 0.007313632 0.003835233 418s [331] 0.006884091 0.004212735 0.003835233 0.004212735 0.004212735 0.003835233 418s [337] 0.003835233 0.006884091 0.003835233 0.004212735 0.003835233 0.003835233 418s [343] 0.006025075 0.003835233 0.004212735 0.003835233 0.006884091 0.007313632 418s [349] 0.003835233 0.003835233 0.003835233 0.007313632 0.006884091 0.004212735 418s [355] 0.007313632 0.003835233 0.006884091 0.004212735 0.004212735 0.003835233 418s [361] 0.003835233 0.003835233 0.003835233 0.006025075 0.004212735 0.007313632 418s [367] 0.004212735 0.007313632 0.007313632 0.003835233 0.003835233 0.006884091 418s [373] 0.003835233 0.006884091 0.003835233 0.007313632 0.007313632 0.003835233 418s [379] 0.007313632 0.007313632 0.006884091 0.006884091 0.007313632 0.004212735 418s [385] 0.007313632 0.004212735 0.007313632 0.003835233 0.006884091 0.006025075 418s [391] 0.003835233 0.006025075 0.006025075 0.003835233 0.003835233 0.004212735 418s [397] 0.004212735 0.004212735 0.006025075 0.006025075 0.003835233 0.006025075 418s [403] 0.006884091 0.004212735 0.004212735 0.006025075 0.004212735 0.003835233 418s [409] 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 0.006884091 418s [415] 0.003835233 0.006884091 0.007313632 0.006884091 0.003835233 0.004212735 418s [421] 0.003835233 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 418s [427] 0.004212735 0.006025075 0.007313632 0.003835233 0.006884091 0.003835233 418s [433] 0.003835233 0.003835233 0.006025075 0.003835233 0.006884091 0.006025075 418s [439] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 418s [445] 0.006025075 0.006025075 0.003835233 0.003835233 0.006025075 0.004212735 418s [451] 0.007313632 0.003835233 0.006884091 0.006025075 0.003835233 0.006025075 418s [457] 0.003835233 0.006025075 0.007313632 0.003835233 0.003835233 0.006884091 418s [463] 0.003835233 0.004212735 0.007313632 0.007313632 0.006884091 0.007313632 418s [469] 0.003835233 0.003835233 0.006025075 0.003835233 0.003835233 0.004212735 418s [475] 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 418s [481] 0.006025075 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 418s [487] 0.007313632 0.006884091 0.007313632 0.003835233 0.006884091 0.007313632 418s [493] 0.006884091 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 418s [499] 0.004212735 0.003835233 0.007313632 0.006884091 0.007313632 0.007313632 418s [505] 0.003835233 0.006025075 0.003835233 0.007313632 0.007313632 0.003835233 418s [511] 0.004212735 0.003835233 0.007313632 0.003835233 0.003835233 0.004212735 418s [517] 0.003835233 0.003835233 0.004212735 0.006025075 0.004212735 0.004212735 418s [523] 0.007313632 0.004212735 0.004212735 0.004212735 0.004212735 0.006025075 418s [529] 0.003835233 0.007313632 0.004212735 0.006884091 0.007313632 0.003835233 418s [535] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.006025075 418s [541] 0.004212735 0.006884091 0.004212735 0.007313632 0.004212735 0.003835233 418s [547] 0.004212735 0.006025075 0.006025075 0.007313632 0.004212735 0.006884091 418s [553] 0.006884091 0.003835233 0.006025075 0.004212735 0.006025075 0.003835233 418s [559] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.004212735 418s [565] 0.004212735 0.003835233 0.006884091 0.006884091 0.004212735 0.003835233 418s [571] 0.006884091 0.006025075 0.006025075 0.003835233 0.006025075 0.003835233 418s [577] 0.004212735 0.004212735 0.006025075 0.003835233 0.003835233 0.006884091 418s [583] 0.004212735 0.007313632 0.003835233 0.006884091 0.007313632 0.003835233 418s [589] 0.003835233 0.003835233 0.007313632 0.003835233 0.007313632 0.003835233 418s [595] 0.007313632 0.007313632 0.006884091 0.004212735 0.004212735 0.003835233 418s [601] 0.003835233 0.003835233 0.007313632 0.004212735 0.004212735 0.003835233 418s [607] 0.003835233 0.007313632 0.007313632 0.006884091 0.004212735 0.007313632 418s [613] 0.007313632 0.003835233 0.003835233 0.006025075 0.007313632 0.003835233 418s [619] 0.006884091 0.003835233 0.006884091 0.006025075 0.003835233 0.003835233 418s [625] 0.007313632 0.003835233 0.004212735 0.004212735 0.006025075 0.006025075 418s [631] 0.006025075 0.006025075 0.006025075 0.003835233 0.007313632 0.004212735 418s [637] 0.006025075 0.003835233 0.006884091 0.007313632 0.003835233 0.006884091 418s [643] 0.003835233 0.006025075 0.003835233 0.004212735 0.004212735 0.003835233 418s [649] 0.006025075 0.003835233 0.006884091 0.006884091 0.007313632 0.007313632 418s [655] 0.006884091 0.003835233 0.004212735 0.004212735 0.003835233 0.003835233 418s [661] 0.006025075 0.003835233 0.004212735 0.006884091 0.003835233 0.003835233 418s [667] 0.003835233 0.003835233 0.003835233 0.003835233 0.006025075 0.003835233 418s [673] 0.004212735 0.007313632 0.003835233 0.003835233 0.007313632 0.006025075 418s [679] 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 418s [685] 0.007313632 0.007313632 0.006884091 0.004212735 0.006025075 0.004212735 418s [691] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.003835233 418s [697] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 418s [703] 0.006884091 0.006884091 0.003835233 0.003835233 0.003835233 0.003835233 418s [709] 0.004212735 0.006884091 0.003835233 0.007313632 0.003835233 418s 418s [1] 573.604 418s [1] -1502.21 418s [1] -1502.21 418s Dose Response Model 418s 418s Model: exponential 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -2.72e-01 -5.96e-02 -5.44e-06 5.59e-02 2.43e-01 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -4.57e-01 1.03e-02 418s e1 1.24e-01 9.45e-02 418s delta 9.69e+02 4.79e+02 418s age -2.46e-04 1.09e-04 418s centergreen -2.26e-03 9.93e-03 418s centerred 7.10e-03 9.88e-03 418s centersilver 1.68e-02 1.02e-02 418s centeryellow -4.45e-03 1.01e-02 418s 418s Residual standard error: 0.0838 418s Degrees of freedom: 705 418s 418s Formula: y ~ cbind(XX, exponential(x, 0, 1, delta)) 418s 418s Parameters: 418s Estimate Std. Error t value Pr(>|t|) 418s delta 9.692e+02 4.795e+02 2.021 0.0436 * 418s .lin.(Intercept) -4.574e-01 1.035e-02 -44.200 <2e-16 *** 418s .lin.centergreen -2.256e-03 9.934e-03 -0.227 0.8204 418s .lin.centerred 7.104e-03 9.875e-03 0.719 0.4721 418s .lin.centersilver 1.682e-02 1.018e-02 1.652 0.0989 . 418s .lin.centeryellow -4.446e-03 1.005e-02 -0.442 0.6584 418s .lin.age -2.463e-04 1.090e-04 -2.259 0.0242 * 418s .lin7 1.244e-01 9.455e-02 1.316 0.1886 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.0838 on 705 degrees of freedom 418s 418s Number of iterations to convergence: 7 418s Achieved convergence tolerance: 8.746e-06 418s 418s e0 e1 delta age 418s e0 1.070950e-04 -3.644583e-04 -1.760351e+00 -6.235809e-07 418s e1 -3.644583e-04 8.939482e-03 4.524833e+01 -1.892275e-07 418s delta -1.760351e+00 4.524833e+01 2.299190e+05 -9.417514e-04 418s age -6.235809e-07 -1.892275e-07 -9.417514e-04 1.188604e-08 418s centergreen -4.990019e-05 -7.223387e-05 -3.668152e-01 4.308966e-08 418s centerred -5.090480e-05 -5.257812e-05 -2.765207e-01 2.992730e-08 418s centersilver -5.269569e-05 -5.104404e-05 -2.725146e-01 5.557593e-08 418s centeryellow -5.416568e-05 -3.395837e-05 -1.820278e-01 7.695026e-08 418s centergreen centerred centersilver centeryellow 418s e0 -4.990019e-05 -5.090480e-05 -5.269569e-05 -5.416568e-05 418s e1 -7.223387e-05 -5.257812e-05 -5.104404e-05 -3.395837e-05 418s delta -3.668152e-01 -2.765207e-01 -2.725146e-01 -1.820278e-01 418s age 4.308966e-08 2.992730e-08 5.557593e-08 7.695026e-08 418s centergreen 9.869293e-05 5.105736e-05 5.114013e-05 5.107251e-05 418s centerred 5.105736e-05 9.752101e-05 5.111632e-05 5.102188e-05 418s centersilver 5.114013e-05 5.111632e-05 1.036881e-04 5.122455e-05 418s centeryellow 5.107251e-05 5.102188e-05 5.122455e-05 1.010538e-04 418s delta .lin.(Intercept) .lin.centergreen 418s delta 2.299104e+05 -1.760315e+00 -3.668085e-01 418s .lin.(Intercept) -1.760315e+00 1.070949e-04 -4.990020e-05 418s .lin.centergreen -3.668085e-01 -4.990020e-05 9.869293e-05 418s .lin.centerred -2.765154e-01 -5.090480e-05 5.105736e-05 418s .lin.centersilver -2.725097e-01 -5.269570e-05 5.114013e-05 418s .lin.centeryellow -1.820244e-01 -5.416569e-05 5.107251e-05 418s .lin.age -9.417341e-04 -6.235810e-07 4.308966e-08 418s .lin7 4.524658e+01 -3.644504e-04 -7.223243e-05 418s .lin.centerred .lin.centersilver .lin.centeryellow 418s delta -2.765154e-01 -2.725097e-01 -1.820244e-01 418s .lin.(Intercept) -5.090480e-05 -5.269570e-05 -5.416569e-05 418s .lin.centergreen 5.105736e-05 5.114013e-05 5.107251e-05 418s .lin.centerred 9.752101e-05 5.111632e-05 5.102188e-05 418s .lin.centersilver 5.111632e-05 1.036881e-04 5.122455e-05 418s .lin.centeryellow 5.102188e-05 5.122455e-05 1.010538e-04 418s .lin.age 2.992730e-08 5.557593e-08 7.695026e-08 418s .lin7 -5.257703e-05 -5.104303e-05 -3.395767e-05 418s .lin.age .lin7 418s delta -9.417341e-04 4.524658e+01 418s .lin.(Intercept) -6.235810e-07 -3.644504e-04 418s .lin.centergreen 4.308966e-08 -7.223243e-05 418s .lin.centerred 2.992730e-08 -5.257703e-05 418s .lin.centersilver 5.557593e-08 -5.104303e-05 418s .lin.centeryellow 7.695026e-08 -3.395767e-05 418s .lin.age 1.188604e-08 -1.892238e-07 418s .lin7 -1.892238e-07 8.939124e-03 418s $fit 418s [1] 0.00000000 0.01352276 418s 418s $se.fit 418s [1] 0.000000000 0.003277925 418s 418s $fit 418s [1] -0.4697265 -0.4562037 418s 418s $se.fit 418s [1] 0.008628557 0.007549824 418s 418s [1] 571.7033 418s [1] 4189.744 418s [1] 4189.744 418s Dose Response Model 418s 418s Model: linear 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -20.3923 -4.1973 -0.0226 3.8448 25.3694 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -11.2122 0.393654 418s delta 0.0136 0.000531 418s 418s Residual standard error: 6.43 418s Degrees of freedom: 636 418s 418s Call: 418s lm(formula = y ~ x, data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -25.3694 -3.8448 0.0226 4.1973 20.3923 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -1.121e+01 3.937e-01 -28.48 <2e-16 *** 418s x 1.358e-02 5.313e-04 25.57 <2e-16 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 6.433 on 636 degrees of freedom 418s Multiple R-squared: 0.5069, Adjusted R-squared: 0.5061 418s F-statistic: 653.7 on 1 and 636 DF, p-value: < 2.2e-16 418s 418s e0 delta 418s e0 0.1549638101 -1.594693e-04 418s delta -0.0001594693 2.822434e-07 418s (Intercept) x 418s (Intercept) 0.1549638101 -1.594693e-04 418s x -0.0001594693 2.822434e-07 418s $fit 418s [1] 3.382287 6.560821 12.605469 12.605469 17.251020 0.000000 0.000000 418s [8] 6.560821 17.251020 3.382287 15.892672 3.382287 0.000000 9.671438 418s [15] 15.892672 17.251020 12.605469 17.251020 3.382287 17.251020 17.251020 418s [22] 9.671438 3.382287 12.605469 0.000000 12.605469 3.382287 6.560821 418s [29] 0.000000 17.251020 0.000000 9.671438 12.605469 3.382287 3.382287 418s [36] 0.000000 0.000000 12.605469 0.000000 12.605469 0.000000 15.892672 418s [43] 12.605469 15.892672 3.382287 17.251020 17.251020 6.560821 3.382287 418s [50] 0.000000 9.671438 17.251020 15.892672 0.000000 3.382287 17.251020 418s [57] 6.560821 17.251020 0.000000 3.382287 12.605469 12.605469 0.000000 418s [64] 0.000000 15.892672 15.892672 0.000000 12.605469 15.892672 3.382287 418s [71] 15.892672 6.560821 3.382287 17.251020 12.605469 0.000000 12.605469 418s [78] 12.605469 3.382287 0.000000 0.000000 0.000000 3.382287 3.382287 418s [85] 3.382287 6.560821 3.382287 0.000000 3.382287 17.251020 6.560821 418s [92] 3.382287 17.251020 9.671438 3.382287 0.000000 3.382287 3.382287 418s [99] 12.605469 0.000000 3.382287 3.382287 12.605469 0.000000 0.000000 418s [106] 17.251020 0.000000 6.560821 15.892672 17.251020 3.382287 17.251020 418s [113] 3.382287 0.000000 0.000000 3.382287 6.560821 0.000000 6.560821 418s [120] 3.382287 0.000000 0.000000 6.560821 15.892672 12.605469 12.605469 418s [127] 0.000000 17.251020 0.000000 17.251020 3.382287 0.000000 12.605469 418s [134] 17.251020 0.000000 3.382287 0.000000 6.560821 6.560821 6.560821 418s [141] 3.382287 17.251020 0.000000 0.000000 3.382287 0.000000 15.892672 418s [148] 17.251020 3.382287 15.892672 0.000000 17.251020 6.560821 3.382287 418s [155] 12.605469 6.560821 6.560821 3.382287 3.382287 0.000000 3.382287 418s [162] 0.000000 3.382287 12.605469 3.382287 0.000000 17.251020 0.000000 418s [169] 0.000000 3.382287 17.251020 3.382287 17.251020 15.892672 6.560821 418s [176] 12.605469 3.382287 0.000000 12.605469 0.000000 12.605469 17.251020 418s [183] 12.605469 0.000000 0.000000 12.605469 3.382287 12.605469 17.251020 418s [190] 3.382287 3.382287 17.251020 3.382287 6.560821 3.382287 17.251020 418s [197] 17.251020 0.000000 12.605469 0.000000 12.605469 3.382287 6.560821 418s [204] 12.605469 12.605469 3.382287 3.382287 12.605469 17.251020 12.605469 418s [211] 3.382287 3.382287 17.251020 0.000000 6.560821 3.382287 3.382287 418s [218] 0.000000 6.560821 0.000000 6.560821 6.560821 3.382287 0.000000 418s [225] 3.382287 3.382287 17.251020 3.382287 0.000000 17.251020 3.382287 418s [232] 6.560821 17.251020 0.000000 0.000000 3.382287 3.382287 12.605469 418s [239] 6.560821 12.605469 3.382287 12.605469 17.251020 6.560821 17.251020 418s [246] 17.251020 15.892672 0.000000 3.382287 3.382287 3.382287 0.000000 418s [253] 12.605469 15.892672 6.560821 3.382287 3.382287 0.000000 0.000000 418s [260] 12.605469 6.560821 3.382287 3.382287 12.605469 17.251020 0.000000 418s [267] 6.560821 15.892672 3.382287 15.892672 3.382287 12.605469 0.000000 418s [274] 17.251020 15.892672 6.560821 3.382287 12.605469 0.000000 3.382287 418s [281] 3.382287 12.605469 3.382287 0.000000 17.251020 15.892672 17.251020 418s [288] 3.382287 17.251020 3.382287 3.382287 3.382287 15.892672 0.000000 418s [295] 0.000000 17.251020 17.251020 12.605469 0.000000 12.605469 17.251020 418s [302] 15.892672 15.892672 0.000000 3.382287 12.605469 12.605469 15.892672 418s [309] 6.560821 15.892672 12.605469 12.605469 17.251020 0.000000 17.251020 418s [316] 3.382287 17.251020 3.382287 12.605469 0.000000 6.560821 3.382287 418s [323] 0.000000 15.892672 17.251020 17.251020 17.251020 3.382287 6.560821 418s [330] 0.000000 0.000000 12.605469 12.605469 12.605469 0.000000 12.605469 418s [337] 0.000000 15.892672 6.560821 17.251020 12.605469 12.605469 6.560821 418s [344] 0.000000 0.000000 17.251020 0.000000 0.000000 12.605469 0.000000 418s [351] 3.382287 3.382287 6.560821 17.251020 9.671438 0.000000 9.671438 418s [358] 9.671438 12.605469 3.382287 12.605469 3.382287 17.251020 0.000000 418s [365] 12.605469 0.000000 3.382287 0.000000 3.382287 6.560821 0.000000 418s [372] 6.560821 6.560821 17.251020 15.892672 0.000000 17.251020 0.000000 418s [379] 3.382287 17.251020 3.382287 12.605469 3.382287 3.382287 12.605469 418s [386] 3.382287 3.382287 0.000000 15.892672 0.000000 12.605469 0.000000 418s [393] 15.892672 6.560821 15.892672 15.892672 6.560821 6.560821 3.382287 418s [400] 3.382287 17.251020 17.251020 6.560821 12.605469 9.671438 15.892672 418s [407] 17.251020 6.560821 3.382287 0.000000 6.560821 6.560821 15.892672 418s [414] 3.382287 0.000000 0.000000 0.000000 0.000000 3.382287 3.382287 418s [421] 0.000000 3.382287 3.382287 12.605469 17.251020 17.251020 17.251020 418s [428] 0.000000 15.892672 17.251020 17.251020 0.000000 0.000000 17.251020 418s [435] 12.605469 6.560821 0.000000 0.000000 3.382287 0.000000 15.892672 418s [442] 12.605469 17.251020 3.382287 12.605469 0.000000 17.251020 0.000000 418s [449] 6.560821 12.605469 6.560821 12.605469 15.892672 12.605469 12.605469 418s [456] 0.000000 0.000000 3.382287 0.000000 3.382287 0.000000 0.000000 418s [463] 0.000000 17.251020 6.560821 17.251020 12.605469 12.605469 3.382287 418s [470] 17.251020 0.000000 3.382287 0.000000 6.560821 0.000000 0.000000 418s [477] 3.382287 15.892672 3.382287 12.605469 0.000000 3.382287 12.605469 418s [484] 6.560821 17.251020 9.671438 15.892672 17.251020 15.892672 0.000000 418s [491] 0.000000 3.382287 3.382287 17.251020 0.000000 6.560821 12.605469 418s [498] 12.605469 12.605469 3.382287 3.382287 3.382287 15.892672 0.000000 418s [505] 6.560821 3.382287 17.251020 3.382287 12.605469 12.605469 15.892672 418s [512] 0.000000 12.605469 17.251020 6.560821 0.000000 3.382287 0.000000 418s [519] 15.892672 0.000000 12.605469 12.605469 0.000000 17.251020 0.000000 418s [526] 9.671438 0.000000 3.382287 15.892672 3.382287 3.382287 3.382287 418s [533] 17.251020 15.892672 0.000000 0.000000 0.000000 15.892672 6.560821 418s [540] 17.251020 17.251020 6.560821 0.000000 0.000000 3.382287 12.605469 418s [547] 12.605469 0.000000 3.382287 15.892672 0.000000 0.000000 3.382287 418s [554] 0.000000 0.000000 0.000000 17.251020 17.251020 17.251020 12.605469 418s [561] 0.000000 15.892672 0.000000 3.382287 3.382287 12.605469 6.560821 418s [568] 12.605469 3.382287 3.382287 0.000000 17.251020 6.560821 15.892672 418s [575] 0.000000 9.671438 3.382287 3.382287 0.000000 12.605469 3.382287 418s [582] 12.605469 3.382287 0.000000 6.560821 0.000000 3.382287 17.251020 418s [589] 3.382287 12.605469 12.605469 17.251020 3.382287 9.671438 0.000000 418s [596] 17.251020 0.000000 6.560821 9.671438 9.671438 0.000000 0.000000 418s [603] 0.000000 12.605469 17.251020 12.605469 12.605469 6.560821 6.560821 418s [610] 15.892672 3.382287 6.560821 6.560821 9.671438 17.251020 17.251020 418s [617] 0.000000 3.382287 12.605469 15.892672 3.382287 0.000000 17.251020 418s [624] 12.605469 6.560821 17.251020 17.251020 0.000000 6.560821 15.892672 418s [631] 6.560821 6.560821 0.000000 15.892672 17.251020 0.000000 3.382287 418s [638] 17.251020 418s 418s $se.fit 418s [1] 0.1322852 0.2566014 0.4930147 0.4930147 0.6747076 0.0000000 0.0000000 418s [8] 0.2566014 0.6747076 0.1322852 0.6215810 0.1322852 0.0000000 0.3782613 418s [15] 0.6215810 0.6747076 0.4930147 0.6747076 0.1322852 0.6747076 0.6747076 418s [22] 0.3782613 0.1322852 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 418s [29] 0.0000000 0.6747076 0.0000000 0.3782613 0.4930147 0.1322852 0.1322852 418s [36] 0.0000000 0.0000000 0.4930147 0.0000000 0.4930147 0.0000000 0.6215810 418s [43] 0.4930147 0.6215810 0.1322852 0.6747076 0.6747076 0.2566014 0.1322852 418s [50] 0.0000000 0.3782613 0.6747076 0.6215810 0.0000000 0.1322852 0.6747076 418s [57] 0.2566014 0.6747076 0.0000000 0.1322852 0.4930147 0.4930147 0.0000000 418s [64] 0.0000000 0.6215810 0.6215810 0.0000000 0.4930147 0.6215810 0.1322852 418s [71] 0.6215810 0.2566014 0.1322852 0.6747076 0.4930147 0.0000000 0.4930147 418s [78] 0.4930147 0.1322852 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 418s [85] 0.1322852 0.2566014 0.1322852 0.0000000 0.1322852 0.6747076 0.2566014 418s [92] 0.1322852 0.6747076 0.3782613 0.1322852 0.0000000 0.1322852 0.1322852 418s [99] 0.4930147 0.0000000 0.1322852 0.1322852 0.4930147 0.0000000 0.0000000 418s [106] 0.6747076 0.0000000 0.2566014 0.6215810 0.6747076 0.1322852 0.6747076 418s [113] 0.1322852 0.0000000 0.0000000 0.1322852 0.2566014 0.0000000 0.2566014 418s [120] 0.1322852 0.0000000 0.0000000 0.2566014 0.6215810 0.4930147 0.4930147 418s [127] 0.0000000 0.6747076 0.0000000 0.6747076 0.1322852 0.0000000 0.4930147 418s [134] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.2566014 0.2566014 418s [141] 0.1322852 0.6747076 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 418s [148] 0.6747076 0.1322852 0.6215810 0.0000000 0.6747076 0.2566014 0.1322852 418s [155] 0.4930147 0.2566014 0.2566014 0.1322852 0.1322852 0.0000000 0.1322852 418s [162] 0.0000000 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.0000000 418s [169] 0.0000000 0.1322852 0.6747076 0.1322852 0.6747076 0.6215810 0.2566014 418s [176] 0.4930147 0.1322852 0.0000000 0.4930147 0.0000000 0.4930147 0.6747076 418s [183] 0.4930147 0.0000000 0.0000000 0.4930147 0.1322852 0.4930147 0.6747076 418s [190] 0.1322852 0.1322852 0.6747076 0.1322852 0.2566014 0.1322852 0.6747076 418s [197] 0.6747076 0.0000000 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 418s [204] 0.4930147 0.4930147 0.1322852 0.1322852 0.4930147 0.6747076 0.4930147 418s [211] 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.1322852 0.1322852 418s [218] 0.0000000 0.2566014 0.0000000 0.2566014 0.2566014 0.1322852 0.0000000 418s [225] 0.1322852 0.1322852 0.6747076 0.1322852 0.0000000 0.6747076 0.1322852 418s [232] 0.2566014 0.6747076 0.0000000 0.0000000 0.1322852 0.1322852 0.4930147 418s [239] 0.2566014 0.4930147 0.1322852 0.4930147 0.6747076 0.2566014 0.6747076 418s [246] 0.6747076 0.6215810 0.0000000 0.1322852 0.1322852 0.1322852 0.0000000 418s [253] 0.4930147 0.6215810 0.2566014 0.1322852 0.1322852 0.0000000 0.0000000 418s [260] 0.4930147 0.2566014 0.1322852 0.1322852 0.4930147 0.6747076 0.0000000 418s [267] 0.2566014 0.6215810 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 418s [274] 0.6747076 0.6215810 0.2566014 0.1322852 0.4930147 0.0000000 0.1322852 418s [281] 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.6215810 0.6747076 418s [288] 0.1322852 0.6747076 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 418s [295] 0.0000000 0.6747076 0.6747076 0.4930147 0.0000000 0.4930147 0.6747076 418s [302] 0.6215810 0.6215810 0.0000000 0.1322852 0.4930147 0.4930147 0.6215810 418s [309] 0.2566014 0.6215810 0.4930147 0.4930147 0.6747076 0.0000000 0.6747076 418s [316] 0.1322852 0.6747076 0.1322852 0.4930147 0.0000000 0.2566014 0.1322852 418s [323] 0.0000000 0.6215810 0.6747076 0.6747076 0.6747076 0.1322852 0.2566014 418s [330] 0.0000000 0.0000000 0.4930147 0.4930147 0.4930147 0.0000000 0.4930147 418s [337] 0.0000000 0.6215810 0.2566014 0.6747076 0.4930147 0.4930147 0.2566014 418s [344] 0.0000000 0.0000000 0.6747076 0.0000000 0.0000000 0.4930147 0.0000000 418s [351] 0.1322852 0.1322852 0.2566014 0.6747076 0.3782613 0.0000000 0.3782613 418s [358] 0.3782613 0.4930147 0.1322852 0.4930147 0.1322852 0.6747076 0.0000000 418s [365] 0.4930147 0.0000000 0.1322852 0.0000000 0.1322852 0.2566014 0.0000000 418s [372] 0.2566014 0.2566014 0.6747076 0.6215810 0.0000000 0.6747076 0.0000000 418s [379] 0.1322852 0.6747076 0.1322852 0.4930147 0.1322852 0.1322852 0.4930147 418s [386] 0.1322852 0.1322852 0.0000000 0.6215810 0.0000000 0.4930147 0.0000000 418s [393] 0.6215810 0.2566014 0.6215810 0.6215810 0.2566014 0.2566014 0.1322852 418s [400] 0.1322852 0.6747076 0.6747076 0.2566014 0.4930147 0.3782613 0.6215810 418s [407] 0.6747076 0.2566014 0.1322852 0.0000000 0.2566014 0.2566014 0.6215810 418s [414] 0.1322852 0.0000000 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 418s [421] 0.0000000 0.1322852 0.1322852 0.4930147 0.6747076 0.6747076 0.6747076 418s [428] 0.0000000 0.6215810 0.6747076 0.6747076 0.0000000 0.0000000 0.6747076 418s [435] 0.4930147 0.2566014 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 418s [442] 0.4930147 0.6747076 0.1322852 0.4930147 0.0000000 0.6747076 0.0000000 418s [449] 0.2566014 0.4930147 0.2566014 0.4930147 0.6215810 0.4930147 0.4930147 418s [456] 0.0000000 0.0000000 0.1322852 0.0000000 0.1322852 0.0000000 0.0000000 418s [463] 0.0000000 0.6747076 0.2566014 0.6747076 0.4930147 0.4930147 0.1322852 418s [470] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.0000000 0.0000000 418s [477] 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 0.1322852 0.4930147 418s [484] 0.2566014 0.6747076 0.3782613 0.6215810 0.6747076 0.6215810 0.0000000 418s [491] 0.0000000 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.4930147 418s [498] 0.4930147 0.4930147 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 418s [505] 0.2566014 0.1322852 0.6747076 0.1322852 0.4930147 0.4930147 0.6215810 418s [512] 0.0000000 0.4930147 0.6747076 0.2566014 0.0000000 0.1322852 0.0000000 418s [519] 0.6215810 0.0000000 0.4930147 0.4930147 0.0000000 0.6747076 0.0000000 418s [526] 0.3782613 0.0000000 0.1322852 0.6215810 0.1322852 0.1322852 0.1322852 418s [533] 0.6747076 0.6215810 0.0000000 0.0000000 0.0000000 0.6215810 0.2566014 418s [540] 0.6747076 0.6747076 0.2566014 0.0000000 0.0000000 0.1322852 0.4930147 418s [547] 0.4930147 0.0000000 0.1322852 0.6215810 0.0000000 0.0000000 0.1322852 418s [554] 0.0000000 0.0000000 0.0000000 0.6747076 0.6747076 0.6747076 0.4930147 418s [561] 0.0000000 0.6215810 0.0000000 0.1322852 0.1322852 0.4930147 0.2566014 418s [568] 0.4930147 0.1322852 0.1322852 0.0000000 0.6747076 0.2566014 0.6215810 418s [575] 0.0000000 0.3782613 0.1322852 0.1322852 0.0000000 0.4930147 0.1322852 418s [582] 0.4930147 0.1322852 0.0000000 0.2566014 0.0000000 0.1322852 0.6747076 418s [589] 0.1322852 0.4930147 0.4930147 0.6747076 0.1322852 0.3782613 0.0000000 418s [596] 0.6747076 0.0000000 0.2566014 0.3782613 0.3782613 0.0000000 0.0000000 418s [603] 0.0000000 0.4930147 0.6747076 0.4930147 0.4930147 0.2566014 0.2566014 418s [610] 0.6215810 0.1322852 0.2566014 0.2566014 0.3782613 0.6747076 0.6747076 418s [617] 0.0000000 0.1322852 0.4930147 0.6215810 0.1322852 0.0000000 0.6747076 418s [624] 0.4930147 0.2566014 0.6747076 0.6747076 0.0000000 0.2566014 0.6215810 418s [631] 0.2566014 0.2566014 0.0000000 0.6215810 0.6747076 0.0000000 0.1322852 418s [638] 0.6747076 418s 418s [1] 73.61884 418s [1] 4193.584 418s [1] 4193.584 418s Dose Response Model 418s 418s Model: linear 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -19.855 -3.996 -0.064 3.775 24.956 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -11.1996 0.811196 418s delta 0.0136 0.000532 418s age -0.0126 0.009027 418s centergreen 0.0191 0.793736 418s centerred 1.1979 0.810341 418s centersilver 0.7446 0.817870 418s centeryellow 1.2027 0.826882 418s 418s Residual standard error: 6.43 418s Degrees of freedom: 631 418s 418s Call: 418s lm(formula = y ~ x + age + center, data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -24.956 -3.775 0.064 3.996 19.855 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -1.120e+01 8.112e-01 -13.806 <2e-16 *** 418s x 1.360e-02 5.316e-04 25.575 <2e-16 *** 418s age -1.255e-02 9.027e-03 -1.391 0.165 418s centergreen 1.906e-02 7.937e-01 0.024 0.981 418s centerred 1.198e+00 8.103e-01 1.478 0.140 418s centersilver 7.446e-01 8.179e-01 0.910 0.363 418s centeryellow 1.203e+00 8.269e-01 1.455 0.146 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 6.427 on 631 degrees of freedom 418s Multiple R-squared: 0.5116, Adjusted R-squared: 0.507 418s F-statistic: 110.2 on 6 and 631 DF, p-value: < 2.2e-16 418s 418s e0 delta age centergreen 418s e0 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 418s delta -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 418s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 418s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 418s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 418s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 418s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 418s centerred centersilver centeryellow 418s e0 -3.460807e-01 -3.642369e-01 -3.253015e-01 418s delta -1.885394e-06 1.847581e-05 3.596102e-06 418s age 2.140485e-04 3.347250e-04 -2.387489e-04 418s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 418s centerred 6.566532e-01 3.366063e-01 3.351988e-01 418s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 418s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 418s (Intercept) x age centergreen 418s (Intercept) 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 418s x -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 418s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 418s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 418s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 418s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 418s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 418s centerred centersilver centeryellow 418s (Intercept) -3.460807e-01 -3.642369e-01 -3.253015e-01 418s x -1.885394e-06 1.847581e-05 3.596102e-06 418s age 2.140485e-04 3.347250e-04 -2.387489e-04 418s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 418s centerred 6.566532e-01 3.366063e-01 3.351988e-01 418s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 418s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 418s $fit 418s [1] 3.385405 6.566871 12.617093 12.617093 17.266927 0.000000 0.000000 418s [8] 6.566871 17.266927 3.385405 15.907326 3.385405 0.000000 9.680356 418s [15] 15.907326 17.266927 12.617093 17.266927 3.385405 17.266927 17.266927 418s [22] 9.680356 3.385405 12.617093 0.000000 12.617093 3.385405 6.566871 418s [29] 0.000000 17.266927 0.000000 9.680356 12.617093 3.385405 3.385405 418s [36] 0.000000 0.000000 12.617093 0.000000 12.617093 0.000000 15.907326 418s [43] 12.617093 15.907326 3.385405 17.266927 17.266927 6.566871 3.385405 418s [50] 0.000000 9.680356 17.266927 15.907326 0.000000 3.385405 17.266927 418s [57] 6.566871 17.266927 0.000000 3.385405 12.617093 12.617093 0.000000 418s [64] 0.000000 15.907326 15.907326 0.000000 12.617093 15.907326 3.385405 418s [71] 15.907326 6.566871 3.385405 17.266927 12.617093 0.000000 12.617093 418s [78] 12.617093 3.385405 0.000000 0.000000 0.000000 3.385405 3.385405 418s [85] 3.385405 6.566871 3.385405 0.000000 3.385405 17.266927 6.566871 418s [92] 3.385405 17.266927 9.680356 3.385405 0.000000 3.385405 3.385405 418s [99] 12.617093 0.000000 3.385405 3.385405 12.617093 0.000000 0.000000 418s [106] 17.266927 0.000000 6.566871 15.907326 17.266927 3.385405 17.266927 418s [113] 3.385405 0.000000 0.000000 3.385405 6.566871 0.000000 6.566871 418s [120] 3.385405 0.000000 0.000000 6.566871 15.907326 12.617093 12.617093 418s [127] 0.000000 17.266927 0.000000 17.266927 3.385405 0.000000 12.617093 418s [134] 17.266927 0.000000 3.385405 0.000000 6.566871 6.566871 6.566871 418s [141] 3.385405 17.266927 0.000000 0.000000 3.385405 0.000000 15.907326 418s [148] 17.266927 3.385405 15.907326 0.000000 17.266927 6.566871 3.385405 418s [155] 12.617093 6.566871 6.566871 3.385405 3.385405 0.000000 3.385405 418s [162] 0.000000 3.385405 12.617093 3.385405 0.000000 17.266927 0.000000 418s [169] 0.000000 3.385405 17.266927 3.385405 17.266927 15.907326 6.566871 418s [176] 12.617093 3.385405 0.000000 12.617093 0.000000 12.617093 17.266927 418s [183] 12.617093 0.000000 0.000000 12.617093 3.385405 12.617093 17.266927 418s [190] 3.385405 3.385405 17.266927 3.385405 6.566871 3.385405 17.266927 418s [197] 17.266927 0.000000 12.617093 0.000000 12.617093 3.385405 6.566871 418s [204] 12.617093 12.617093 3.385405 3.385405 12.617093 17.266927 12.617093 418s [211] 3.385405 3.385405 17.266927 0.000000 6.566871 3.385405 3.385405 418s [218] 0.000000 6.566871 0.000000 6.566871 6.566871 3.385405 0.000000 418s [225] 3.385405 3.385405 17.266927 3.385405 0.000000 17.266927 3.385405 418s [232] 6.566871 17.266927 0.000000 0.000000 3.385405 3.385405 12.617093 418s [239] 6.566871 12.617093 3.385405 12.617093 17.266927 6.566871 17.266927 418s [246] 17.266927 15.907326 0.000000 3.385405 3.385405 3.385405 0.000000 418s [253] 12.617093 15.907326 6.566871 3.385405 3.385405 0.000000 0.000000 418s [260] 12.617093 6.566871 3.385405 3.385405 12.617093 17.266927 0.000000 418s [267] 6.566871 15.907326 3.385405 15.907326 3.385405 12.617093 0.000000 418s [274] 17.266927 15.907326 6.566871 3.385405 12.617093 0.000000 3.385405 418s [281] 3.385405 12.617093 3.385405 0.000000 17.266927 15.907326 17.266927 418s [288] 3.385405 17.266927 3.385405 3.385405 3.385405 15.907326 0.000000 418s [295] 0.000000 17.266927 17.266927 12.617093 0.000000 12.617093 17.266927 418s [302] 15.907326 15.907326 0.000000 3.385405 12.617093 12.617093 15.907326 418s [309] 6.566871 15.907326 12.617093 12.617093 17.266927 0.000000 17.266927 418s [316] 3.385405 17.266927 3.385405 12.617093 0.000000 6.566871 3.385405 418s [323] 0.000000 15.907326 17.266927 17.266927 17.266927 3.385405 6.566871 418s [330] 0.000000 0.000000 12.617093 12.617093 12.617093 0.000000 12.617093 418s [337] 0.000000 15.907326 6.566871 17.266927 12.617093 12.617093 6.566871 418s [344] 0.000000 0.000000 17.266927 0.000000 0.000000 12.617093 0.000000 418s [351] 3.385405 3.385405 6.566871 17.266927 9.680356 0.000000 9.680356 418s [358] 9.680356 12.617093 3.385405 12.617093 3.385405 17.266927 0.000000 418s [365] 12.617093 0.000000 3.385405 0.000000 3.385405 6.566871 0.000000 418s [372] 6.566871 6.566871 17.266927 15.907326 0.000000 17.266927 0.000000 418s [379] 3.385405 17.266927 3.385405 12.617093 3.385405 3.385405 12.617093 418s [386] 3.385405 3.385405 0.000000 15.907326 0.000000 12.617093 0.000000 418s [393] 15.907326 6.566871 15.907326 15.907326 6.566871 6.566871 3.385405 418s [400] 3.385405 17.266927 17.266927 6.566871 12.617093 9.680356 15.907326 418s [407] 17.266927 6.566871 3.385405 0.000000 6.566871 6.566871 15.907326 418s [414] 3.385405 0.000000 0.000000 0.000000 0.000000 3.385405 3.385405 418s [421] 0.000000 3.385405 3.385405 12.617093 17.266927 17.266927 17.266927 418s [428] 0.000000 15.907326 17.266927 17.266927 0.000000 0.000000 17.266927 418s [435] 12.617093 6.566871 0.000000 0.000000 3.385405 0.000000 15.907326 418s [442] 12.617093 17.266927 3.385405 12.617093 0.000000 17.266927 0.000000 418s [449] 6.566871 12.617093 6.566871 12.617093 15.907326 12.617093 12.617093 418s [456] 0.000000 0.000000 3.385405 0.000000 3.385405 0.000000 0.000000 418s [463] 0.000000 17.266927 6.566871 17.266927 12.617093 12.617093 3.385405 418s [470] 17.266927 0.000000 3.385405 0.000000 6.566871 0.000000 0.000000 418s [477] 3.385405 15.907326 3.385405 12.617093 0.000000 3.385405 12.617093 418s [484] 6.566871 17.266927 9.680356 15.907326 17.266927 15.907326 0.000000 418s [491] 0.000000 3.385405 3.385405 17.266927 0.000000 6.566871 12.617093 418s [498] 12.617093 12.617093 3.385405 3.385405 3.385405 15.907326 0.000000 418s [505] 6.566871 3.385405 17.266927 3.385405 12.617093 12.617093 15.907326 418s [512] 0.000000 12.617093 17.266927 6.566871 0.000000 3.385405 0.000000 418s [519] 15.907326 0.000000 12.617093 12.617093 0.000000 17.266927 0.000000 418s [526] 9.680356 0.000000 3.385405 15.907326 3.385405 3.385405 3.385405 418s [533] 17.266927 15.907326 0.000000 0.000000 0.000000 15.907326 6.566871 418s [540] 17.266927 17.266927 6.566871 0.000000 0.000000 3.385405 12.617093 418s [547] 12.617093 0.000000 3.385405 15.907326 0.000000 0.000000 3.385405 418s [554] 0.000000 0.000000 0.000000 17.266927 17.266927 17.266927 12.617093 418s [561] 0.000000 15.907326 0.000000 3.385405 3.385405 12.617093 6.566871 418s [568] 12.617093 3.385405 3.385405 0.000000 17.266927 6.566871 15.907326 418s [575] 0.000000 9.680356 3.385405 3.385405 0.000000 12.617093 3.385405 418s [582] 12.617093 3.385405 0.000000 6.566871 0.000000 3.385405 17.266927 418s [589] 3.385405 12.617093 12.617093 17.266927 3.385405 9.680356 0.000000 418s [596] 17.266927 0.000000 6.566871 9.680356 9.680356 0.000000 0.000000 418s [603] 0.000000 12.617093 17.266927 12.617093 12.617093 6.566871 6.566871 418s [610] 15.907326 3.385405 6.566871 6.566871 9.680356 17.266927 17.266927 418s [617] 0.000000 3.385405 12.617093 15.907326 3.385405 0.000000 17.266927 418s [624] 12.617093 6.566871 17.266927 17.266927 0.000000 6.566871 15.907326 418s [631] 6.566871 6.566871 0.000000 15.907326 17.266927 0.000000 3.385405 418s [638] 17.266927 418s 418s $se.fit 418s [1] 0.1323718 0.2567693 0.4933373 0.4933373 0.6751491 0.0000000 0.0000000 418s [8] 0.2567693 0.6751491 0.1323718 0.6219878 0.1323718 0.0000000 0.3785088 418s [15] 0.6219878 0.6751491 0.4933373 0.6751491 0.1323718 0.6751491 0.6751491 418s [22] 0.3785088 0.1323718 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 418s [29] 0.0000000 0.6751491 0.0000000 0.3785088 0.4933373 0.1323718 0.1323718 418s [36] 0.0000000 0.0000000 0.4933373 0.0000000 0.4933373 0.0000000 0.6219878 418s [43] 0.4933373 0.6219878 0.1323718 0.6751491 0.6751491 0.2567693 0.1323718 418s [50] 0.0000000 0.3785088 0.6751491 0.6219878 0.0000000 0.1323718 0.6751491 418s [57] 0.2567693 0.6751491 0.0000000 0.1323718 0.4933373 0.4933373 0.0000000 418s [64] 0.0000000 0.6219878 0.6219878 0.0000000 0.4933373 0.6219878 0.1323718 418s [71] 0.6219878 0.2567693 0.1323718 0.6751491 0.4933373 0.0000000 0.4933373 418s [78] 0.4933373 0.1323718 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 418s [85] 0.1323718 0.2567693 0.1323718 0.0000000 0.1323718 0.6751491 0.2567693 418s [92] 0.1323718 0.6751491 0.3785088 0.1323718 0.0000000 0.1323718 0.1323718 418s [99] 0.4933373 0.0000000 0.1323718 0.1323718 0.4933373 0.0000000 0.0000000 418s [106] 0.6751491 0.0000000 0.2567693 0.6219878 0.6751491 0.1323718 0.6751491 418s [113] 0.1323718 0.0000000 0.0000000 0.1323718 0.2567693 0.0000000 0.2567693 418s [120] 0.1323718 0.0000000 0.0000000 0.2567693 0.6219878 0.4933373 0.4933373 418s [127] 0.0000000 0.6751491 0.0000000 0.6751491 0.1323718 0.0000000 0.4933373 418s [134] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.2567693 0.2567693 418s [141] 0.1323718 0.6751491 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 418s [148] 0.6751491 0.1323718 0.6219878 0.0000000 0.6751491 0.2567693 0.1323718 418s [155] 0.4933373 0.2567693 0.2567693 0.1323718 0.1323718 0.0000000 0.1323718 418s [162] 0.0000000 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.0000000 418s [169] 0.0000000 0.1323718 0.6751491 0.1323718 0.6751491 0.6219878 0.2567693 418s [176] 0.4933373 0.1323718 0.0000000 0.4933373 0.0000000 0.4933373 0.6751491 418s [183] 0.4933373 0.0000000 0.0000000 0.4933373 0.1323718 0.4933373 0.6751491 418s [190] 0.1323718 0.1323718 0.6751491 0.1323718 0.2567693 0.1323718 0.6751491 418s [197] 0.6751491 0.0000000 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 418s [204] 0.4933373 0.4933373 0.1323718 0.1323718 0.4933373 0.6751491 0.4933373 418s [211] 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.1323718 0.1323718 418s [218] 0.0000000 0.2567693 0.0000000 0.2567693 0.2567693 0.1323718 0.0000000 418s [225] 0.1323718 0.1323718 0.6751491 0.1323718 0.0000000 0.6751491 0.1323718 418s [232] 0.2567693 0.6751491 0.0000000 0.0000000 0.1323718 0.1323718 0.4933373 418s [239] 0.2567693 0.4933373 0.1323718 0.4933373 0.6751491 0.2567693 0.6751491 418s [246] 0.6751491 0.6219878 0.0000000 0.1323718 0.1323718 0.1323718 0.0000000 418s [253] 0.4933373 0.6219878 0.2567693 0.1323718 0.1323718 0.0000000 0.0000000 418s [260] 0.4933373 0.2567693 0.1323718 0.1323718 0.4933373 0.6751491 0.0000000 418s [267] 0.2567693 0.6219878 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 418s [274] 0.6751491 0.6219878 0.2567693 0.1323718 0.4933373 0.0000000 0.1323718 418s [281] 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.6219878 0.6751491 418s [288] 0.1323718 0.6751491 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 418s [295] 0.0000000 0.6751491 0.6751491 0.4933373 0.0000000 0.4933373 0.6751491 418s [302] 0.6219878 0.6219878 0.0000000 0.1323718 0.4933373 0.4933373 0.6219878 418s [309] 0.2567693 0.6219878 0.4933373 0.4933373 0.6751491 0.0000000 0.6751491 418s [316] 0.1323718 0.6751491 0.1323718 0.4933373 0.0000000 0.2567693 0.1323718 418s [323] 0.0000000 0.6219878 0.6751491 0.6751491 0.6751491 0.1323718 0.2567693 418s [330] 0.0000000 0.0000000 0.4933373 0.4933373 0.4933373 0.0000000 0.4933373 418s [337] 0.0000000 0.6219878 0.2567693 0.6751491 0.4933373 0.4933373 0.2567693 418s [344] 0.0000000 0.0000000 0.6751491 0.0000000 0.0000000 0.4933373 0.0000000 418s [351] 0.1323718 0.1323718 0.2567693 0.6751491 0.3785088 0.0000000 0.3785088 418s [358] 0.3785088 0.4933373 0.1323718 0.4933373 0.1323718 0.6751491 0.0000000 418s [365] 0.4933373 0.0000000 0.1323718 0.0000000 0.1323718 0.2567693 0.0000000 418s [372] 0.2567693 0.2567693 0.6751491 0.6219878 0.0000000 0.6751491 0.0000000 418s [379] 0.1323718 0.6751491 0.1323718 0.4933373 0.1323718 0.1323718 0.4933373 418s [386] 0.1323718 0.1323718 0.0000000 0.6219878 0.0000000 0.4933373 0.0000000 418s [393] 0.6219878 0.2567693 0.6219878 0.6219878 0.2567693 0.2567693 0.1323718 418s [400] 0.1323718 0.6751491 0.6751491 0.2567693 0.4933373 0.3785088 0.6219878 418s [407] 0.6751491 0.2567693 0.1323718 0.0000000 0.2567693 0.2567693 0.6219878 418s [414] 0.1323718 0.0000000 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 418s [421] 0.0000000 0.1323718 0.1323718 0.4933373 0.6751491 0.6751491 0.6751491 418s [428] 0.0000000 0.6219878 0.6751491 0.6751491 0.0000000 0.0000000 0.6751491 418s [435] 0.4933373 0.2567693 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 418s [442] 0.4933373 0.6751491 0.1323718 0.4933373 0.0000000 0.6751491 0.0000000 418s [449] 0.2567693 0.4933373 0.2567693 0.4933373 0.6219878 0.4933373 0.4933373 418s [456] 0.0000000 0.0000000 0.1323718 0.0000000 0.1323718 0.0000000 0.0000000 418s [463] 0.0000000 0.6751491 0.2567693 0.6751491 0.4933373 0.4933373 0.1323718 418s [470] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.0000000 0.0000000 418s [477] 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 0.1323718 0.4933373 418s [484] 0.2567693 0.6751491 0.3785088 0.6219878 0.6751491 0.6219878 0.0000000 418s [491] 0.0000000 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.4933373 418s [498] 0.4933373 0.4933373 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 418s [505] 0.2567693 0.1323718 0.6751491 0.1323718 0.4933373 0.4933373 0.6219878 418s [512] 0.0000000 0.4933373 0.6751491 0.2567693 0.0000000 0.1323718 0.0000000 418s [519] 0.6219878 0.0000000 0.4933373 0.4933373 0.0000000 0.6751491 0.0000000 418s [526] 0.3785088 0.0000000 0.1323718 0.6219878 0.1323718 0.1323718 0.1323718 418s [533] 0.6751491 0.6219878 0.0000000 0.0000000 0.0000000 0.6219878 0.2567693 418s [540] 0.6751491 0.6751491 0.2567693 0.0000000 0.0000000 0.1323718 0.4933373 418s [547] 0.4933373 0.0000000 0.1323718 0.6219878 0.0000000 0.0000000 0.1323718 418s [554] 0.0000000 0.0000000 0.0000000 0.6751491 0.6751491 0.6751491 0.4933373 418s [561] 0.0000000 0.6219878 0.0000000 0.1323718 0.1323718 0.4933373 0.2567693 418s [568] 0.4933373 0.1323718 0.1323718 0.0000000 0.6751491 0.2567693 0.6219878 418s [575] 0.0000000 0.3785088 0.1323718 0.1323718 0.0000000 0.4933373 0.1323718 418s [582] 0.4933373 0.1323718 0.0000000 0.2567693 0.0000000 0.1323718 0.6751491 418s [589] 0.1323718 0.4933373 0.4933373 0.6751491 0.1323718 0.3785088 0.0000000 418s [596] 0.6751491 0.0000000 0.2567693 0.3785088 0.3785088 0.0000000 0.0000000 418s [603] 0.0000000 0.4933373 0.6751491 0.4933373 0.4933373 0.2567693 0.2567693 418s [610] 0.6219878 0.1323718 0.2567693 0.2567693 0.3785088 0.6751491 0.6751491 418s [617] 0.0000000 0.1323718 0.4933373 0.6219878 0.1323718 0.0000000 0.6751491 418s [624] 0.4933373 0.2567693 0.6751491 0.6751491 0.0000000 0.2567693 0.6219878 418s [631] 0.2567693 0.2567693 0.0000000 0.6219878 0.6751491 0.0000000 0.1323718 418s [638] 0.6751491 418s 418s $fit 418s [1] -11.57621 -11.56261 -11.54901 -10.21661 418s 418s $se.fit 418s [1] 0.6876991 0.6874618 0.6872248 0.6656515 418s 418s $fit 418s 1 2 3 4 418s -11.57621 -11.56261 -11.54901 -10.21661 418s 418s $se.fit 418s 1 2 3 4 418s 0.6876991 0.6874618 0.6872248 0.6656515 418s 418s $df 418s [1] 631 418s 418s $residual.scale 418s [1] 6.427248 418s 418s [1] 73.55102 418s [1] 2768.739 418s [1] 2768.739 418s Dose Response Model 418s 418s Model: linlog 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -18.804 -3.875 -0.163 4.453 17.258 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -13.65 2.626 418s delta 2.21 0.402 418s 418s Residual standard error: 6.12 418s Degrees of freedom: 426 418s 418s Call: 418s lm(formula = y ~ log(x + off), data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -17.2582 -4.4526 0.1627 3.8749 18.8035 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -13.6486 2.6260 -5.197 3.14e-07 *** 418s log(x + off) 2.2117 0.4016 5.508 6.29e-08 *** 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 6.116 on 426 degrees of freedom 418s Multiple R-squared: 0.06648, Adjusted R-squared: 0.06429 418s F-statistic: 30.34 on 1 and 426 DF, p-value: 6.29e-08 418s 418s e0 delta 418s e0 6.896082 -1.0477868 418s delta -1.047787 0.1612436 418s (Intercept) log(x + off) 418s (Intercept) 6.896082 -1.0477868 418s log(x + off) -1.047787 0.1612436 418s $fit 418s [1] 6.008369 5.658359 0.000000 4.514640 4.877164 4.115493 6.008369 6.641510 418s [9] 0.000000 4.115493 5.658359 6.247655 4.514640 6.247655 4.514640 4.514640 418s [17] 4.115493 0.000000 6.008369 4.877164 4.877164 6.247655 6.733679 6.247655 418s [25] 4.115493 4.877164 0.000000 6.733679 6.641510 4.514640 4.514640 5.658359 418s [33] 6.008369 4.877164 4.877164 0.000000 6.008369 6.733679 4.877164 6.008369 418s [41] 6.733679 4.877164 6.008369 6.008369 4.877164 5.658359 4.514640 4.877164 418s [49] 0.000000 4.514640 5.658359 0.000000 4.877164 6.733679 4.877164 4.514640 418s [57] 4.877164 5.658359 6.641510 4.877164 6.733679 5.658359 0.000000 6.247655 418s [65] 6.247655 5.658359 4.877164 4.877164 4.115493 4.877164 6.733679 6.247655 418s [73] 5.658359 5.658359 4.877164 5.535104 6.008369 5.535104 6.247655 6.008369 418s [81] 6.247655 6.008369 5.535104 4.115493 5.658359 4.877164 6.008369 4.877164 418s [89] 6.247655 0.000000 6.008369 4.514640 4.514640 6.008369 4.877164 5.658359 418s [97] 4.877164 6.008369 6.733679 5.658359 4.115493 6.247655 0.000000 6.008369 418s [105] 6.247655 4.877164 6.733679 5.658359 4.115493 5.658359 5.658359 5.658359 418s [113] 6.008369 6.008369 6.733679 4.115493 4.877164 4.115493 4.877164 5.658359 418s [121] 4.514640 6.247655 4.877164 6.641510 4.115493 4.877164 5.658359 4.877164 418s [129] 4.514640 0.000000 6.008369 4.514640 6.733679 4.877164 4.514640 4.877164 418s [137] 5.658359 5.658359 4.115493 6.247655 6.641510 4.877164 5.658359 4.514640 418s [145] 4.115493 4.115493 6.733679 4.877164 0.000000 4.877164 5.658359 4.514640 418s [153] 6.641510 4.514640 4.877164 4.115493 6.247655 4.115493 6.008369 4.877164 418s [161] 4.514640 4.115493 4.877164 6.733679 6.247655 4.514640 4.877164 5.658359 418s [169] 4.115493 0.000000 5.658359 5.658359 4.877164 4.514640 4.115493 4.877164 418s [177] 0.000000 5.658359 6.247655 6.733679 0.000000 6.008369 4.514640 4.877164 418s [185] 0.000000 6.733679 5.658359 6.247655 4.514640 5.535104 5.658359 4.877164 418s [193] 5.658359 6.733679 6.641510 4.514640 6.008369 4.115493 4.877164 4.877164 418s [201] 4.115493 6.247655 5.658359 6.247655 5.535104 0.000000 4.115493 6.641510 418s [209] 6.247655 6.008369 4.115493 4.514640 4.514640 6.641510 6.733679 6.733679 418s [217] 5.658359 5.658359 6.008369 4.115493 5.658359 6.641510 6.641510 4.877164 418s [225] 0.000000 4.877164 0.000000 4.115493 4.877164 5.535104 4.115493 5.658359 418s [233] 6.733679 4.514640 6.733679 4.514640 4.514640 5.658359 6.008369 5.658359 418s [241] 4.877164 4.514640 4.115493 4.115493 4.115493 6.247655 5.658359 0.000000 418s [249] 4.115493 4.514640 6.247655 6.733679 6.008369 4.877164 4.115493 4.514640 418s [257] 0.000000 0.000000 5.658359 5.658359 4.514640 5.658359 4.514640 4.115493 418s [265] 4.877164 4.877164 4.514640 5.658359 6.008369 4.514640 4.115493 0.000000 418s [273] 4.877164 4.877164 4.115493 6.008369 4.514640 6.008369 4.514640 4.877164 418s [281] 6.008369 0.000000 0.000000 5.658359 6.247655 6.008369 6.008369 6.247655 418s [289] 4.877164 4.877164 4.514640 6.008369 6.008369 4.115493 6.641510 6.733679 418s [297] 4.514640 4.877164 4.877164 4.877164 6.008369 6.641510 4.877164 5.658359 418s [305] 4.514640 5.535104 4.877164 6.008369 6.008369 5.658359 4.514640 6.008369 418s [313] 6.247655 5.658359 6.733679 6.008369 6.247655 5.658359 5.535104 4.877164 418s [321] 5.658359 4.877164 4.877164 5.658359 5.658359 4.877164 4.115493 4.877164 418s [329] 5.658359 4.877164 4.877164 4.877164 5.658359 6.733679 6.008369 6.247655 418s [337] 4.877164 5.535104 6.008369 4.115493 6.008369 6.247655 4.115493 6.008369 418s [345] 5.658359 4.877164 6.247655 6.641510 5.658359 4.115493 6.733679 6.008369 418s [353] 5.658359 4.115493 4.514640 4.877164 6.733679 5.658359 0.000000 6.641510 418s [361] 6.733679 4.115493 6.247655 4.877164 4.877164 5.658359 4.514640 4.115493 418s [369] 4.877164 4.877164 4.877164 5.658359 4.877164 0.000000 5.658359 4.877164 418s [377] 4.877164 4.514640 4.514640 6.733679 6.008369 6.733679 4.514640 4.514640 418s [385] 4.115493 5.535104 4.877164 4.877164 6.247655 5.658359 6.733679 4.514640 418s [393] 4.877164 5.658359 6.733679 6.733679 4.514640 6.008369 5.658359 6.733679 418s [401] 6.733679 6.733679 0.000000 6.641510 6.733679 4.115493 4.877164 6.247655 418s [409] 0.000000 4.115493 4.514640 4.877164 4.877164 4.514640 6.733679 6.247655 418s [417] 5.658359 4.877164 4.877164 0.000000 4.877164 4.877164 0.000000 6.008369 418s [425] 4.115493 4.514640 4.877164 0.000000 418s 418s $se.fit 418s [1] 1.0908488 1.0273028 0.0000000 0.8196550 0.8854731 0.7471878 1.0908488 418s [8] 1.2057987 0.0000000 0.7471878 1.0273028 1.1342924 0.8196550 1.1342924 418s [15] 0.8196550 0.8196550 0.7471878 0.0000000 1.0908488 0.8854731 0.8854731 418s [22] 1.1342924 1.2225325 1.1342924 0.7471878 0.8854731 0.0000000 1.2225325 418s [29] 1.2057987 0.8196550 0.8196550 1.0273028 1.0908488 0.8854731 0.8854731 418s [36] 0.0000000 1.0908488 1.2225325 0.8854731 1.0908488 1.2225325 0.8854731 418s [43] 1.0908488 1.0908488 0.8854731 1.0273028 0.8196550 0.8854731 0.0000000 418s [50] 0.8196550 1.0273028 0.0000000 0.8854731 1.2225325 0.8854731 0.8196550 418s [57] 0.8854731 1.0273028 1.2057987 0.8854731 1.2225325 1.0273028 0.0000000 418s [64] 1.1342924 1.1342924 1.0273028 0.8854731 0.8854731 0.7471878 0.8854731 418s [71] 1.2225325 1.1342924 1.0273028 1.0273028 0.8854731 1.0049252 1.0908488 418s [78] 1.0049252 1.1342924 1.0908488 1.1342924 1.0908488 1.0049252 0.7471878 418s [85] 1.0273028 0.8854731 1.0908488 0.8854731 1.1342924 0.0000000 1.0908488 418s [92] 0.8196550 0.8196550 1.0908488 0.8854731 1.0273028 0.8854731 1.0908488 418s [99] 1.2225325 1.0273028 0.7471878 1.1342924 0.0000000 1.0908488 1.1342924 418s [106] 0.8854731 1.2225325 1.0273028 0.7471878 1.0273028 1.0273028 1.0273028 418s [113] 1.0908488 1.0908488 1.2225325 0.7471878 0.8854731 0.7471878 0.8854731 418s [120] 1.0273028 0.8196550 1.1342924 0.8854731 1.2057987 0.7471878 0.8854731 418s [127] 1.0273028 0.8854731 0.8196550 0.0000000 1.0908488 0.8196550 1.2225325 418s [134] 0.8854731 0.8196550 0.8854731 1.0273028 1.0273028 0.7471878 1.1342924 418s [141] 1.2057987 0.8854731 1.0273028 0.8196550 0.7471878 0.7471878 1.2225325 418s [148] 0.8854731 0.0000000 0.8854731 1.0273028 0.8196550 1.2057987 0.8196550 418s [155] 0.8854731 0.7471878 1.1342924 0.7471878 1.0908488 0.8854731 0.8196550 418s [162] 0.7471878 0.8854731 1.2225325 1.1342924 0.8196550 0.8854731 1.0273028 418s [169] 0.7471878 0.0000000 1.0273028 1.0273028 0.8854731 0.8196550 0.7471878 418s [176] 0.8854731 0.0000000 1.0273028 1.1342924 1.2225325 0.0000000 1.0908488 418s [183] 0.8196550 0.8854731 0.0000000 1.2225325 1.0273028 1.1342924 0.8196550 418s [190] 1.0049252 1.0273028 0.8854731 1.0273028 1.2225325 1.2057987 0.8196550 418s [197] 1.0908488 0.7471878 0.8854731 0.8854731 0.7471878 1.1342924 1.0273028 418s [204] 1.1342924 1.0049252 0.0000000 0.7471878 1.2057987 1.1342924 1.0908488 418s [211] 0.7471878 0.8196550 0.8196550 1.2057987 1.2225325 1.2225325 1.0273028 418s [218] 1.0273028 1.0908488 0.7471878 1.0273028 1.2057987 1.2057987 0.8854731 418s [225] 0.0000000 0.8854731 0.0000000 0.7471878 0.8854731 1.0049252 0.7471878 418s [232] 1.0273028 1.2225325 0.8196550 1.2225325 0.8196550 0.8196550 1.0273028 418s [239] 1.0908488 1.0273028 0.8854731 0.8196550 0.7471878 0.7471878 0.7471878 418s [246] 1.1342924 1.0273028 0.0000000 0.7471878 0.8196550 1.1342924 1.2225325 418s [253] 1.0908488 0.8854731 0.7471878 0.8196550 0.0000000 0.0000000 1.0273028 418s [260] 1.0273028 0.8196550 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 418s [267] 0.8196550 1.0273028 1.0908488 0.8196550 0.7471878 0.0000000 0.8854731 418s [274] 0.8854731 0.7471878 1.0908488 0.8196550 1.0908488 0.8196550 0.8854731 418s [281] 1.0908488 0.0000000 0.0000000 1.0273028 1.1342924 1.0908488 1.0908488 418s [288] 1.1342924 0.8854731 0.8854731 0.8196550 1.0908488 1.0908488 0.7471878 418s [295] 1.2057987 1.2225325 0.8196550 0.8854731 0.8854731 0.8854731 1.0908488 418s [302] 1.2057987 0.8854731 1.0273028 0.8196550 1.0049252 0.8854731 1.0908488 418s [309] 1.0908488 1.0273028 0.8196550 1.0908488 1.1342924 1.0273028 1.2225325 418s [316] 1.0908488 1.1342924 1.0273028 1.0049252 0.8854731 1.0273028 0.8854731 418s [323] 0.8854731 1.0273028 1.0273028 0.8854731 0.7471878 0.8854731 1.0273028 418s [330] 0.8854731 0.8854731 0.8854731 1.0273028 1.2225325 1.0908488 1.1342924 418s [337] 0.8854731 1.0049252 1.0908488 0.7471878 1.0908488 1.1342924 0.7471878 418s [344] 1.0908488 1.0273028 0.8854731 1.1342924 1.2057987 1.0273028 0.7471878 418s [351] 1.2225325 1.0908488 1.0273028 0.7471878 0.8196550 0.8854731 1.2225325 418s [358] 1.0273028 0.0000000 1.2057987 1.2225325 0.7471878 1.1342924 0.8854731 418s [365] 0.8854731 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 0.8854731 418s [372] 1.0273028 0.8854731 0.0000000 1.0273028 0.8854731 0.8854731 0.8196550 418s [379] 0.8196550 1.2225325 1.0908488 1.2225325 0.8196550 0.8196550 0.7471878 418s [386] 1.0049252 0.8854731 0.8854731 1.1342924 1.0273028 1.2225325 0.8196550 418s [393] 0.8854731 1.0273028 1.2225325 1.2225325 0.8196550 1.0908488 1.0273028 418s [400] 1.2225325 1.2225325 1.2225325 0.0000000 1.2057987 1.2225325 0.7471878 418s [407] 0.8854731 1.1342924 0.0000000 0.7471878 0.8196550 0.8854731 0.8854731 418s [414] 0.8196550 1.2225325 1.1342924 1.0273028 0.8854731 0.8854731 0.0000000 418s [421] 0.8854731 0.8854731 0.0000000 1.0908488 0.7471878 0.8196550 0.8854731 418s [428] 0.0000000 418s 418s [1] 40.01633 418s [1] 2773.961 418s [1] 2773.961 418s Dose Response Model 418s 418s Model: linlog 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -17.993 -3.920 -0.142 4.548 17.772 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -12.53812 2.7627 418s delta 2.19176 0.4045 418s age -0.00815 0.0103 418s centergreen -0.11764 0.9231 418s centerred -1.68381 0.9385 418s centersilver -0.40779 0.9137 418s centeryellow -0.83235 0.9332 418s 418s Residual standard error: 6.12 418s Degrees of freedom: 421 418s 418s Call: 418s lm(formula = y ~ log(x + off) + age + center, data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -17.7720 -4.5476 0.1417 3.9205 17.9926 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -12.538125 2.762741 -4.538 7.41e-06 *** 418s log(x + off) 2.191761 0.404501 5.418 1.01e-07 *** 418s age -0.008153 0.010337 -0.789 0.4308 418s centergreen -0.117636 0.923131 -0.127 0.8987 418s centerred -1.683810 0.938487 -1.794 0.0735 . 418s centersilver -0.407788 0.913735 -0.446 0.6556 418s centeryellow -0.832351 0.933224 -0.892 0.3730 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 6.118 on 421 degrees of freedom 418s Multiple R-squared: 0.07685, Adjusted R-squared: 0.06369 418s F-statistic: 5.841 on 6 and 421 DF, p-value: 7.284e-06 418s 418s e0 delta age centergreen 418s e0 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 418s delta -1.065954459 0.1636213662 0.0003614495 -0.0285500750 418s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 418s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 418s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 418s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 418s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 418s centerred centersilver centeryellow 418s e0 -0.3271697994 -0.3433662837 -0.3049047728 418s delta -0.0143714026 -0.0139200933 -0.0188552161 418s age 0.0001539174 0.0004143178 0.0002799329 418s centergreen 0.4142785346 0.4148464502 0.4153997441 418s centerred 0.8807582409 0.4133097826 0.4135270947 418s centersilver 0.4133097826 0.8349108233 0.4142615949 418s centeryellow 0.4135270947 0.4142615949 0.8709075166 418s (Intercept) log(x + off) age centergreen 418s (Intercept) 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 418s log(x + off) -1.065954459 0.1636213662 0.0003614495 -0.0285500750 418s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 418s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 418s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 418s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 418s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 418s centerred centersilver centeryellow 418s (Intercept) -0.3271697994 -0.3433662837 -0.3049047728 418s log(x + off) -0.0143714026 -0.0139200933 -0.0188552161 418s age 0.0001539174 0.0004143178 0.0002799329 418s centergreen 0.4142785346 0.4148464502 0.4153997441 418s centerred 0.8807582409 0.4133097826 0.4135270947 418s centersilver 0.4133097826 0.8349108233 0.4142615949 418s centeryellow 0.4135270947 0.4142615949 0.8709075166 418s $fit 418s [1] -3.511779 -3.480690 -3.450035 -1.567022 418s 418s $se.fit 418s [1] 1.1058048 1.1012159 1.0967017 0.8461873 418s 418s $fit 418s 1 2 3 4 418s -3.511779 -3.480690 -3.450035 -1.567022 418s 418s $se.fit 418s 1 2 3 4 418s 1.1058048 1.1012159 1.0967017 0.8461873 418s 418s $df 418s [1] 421 418s 418s $residual.scale 418s [1] 6.117927 418s 418s [1] 40.47058 418s [1] 54.33574 418s [1] 54.33574 418s Dose Response Model 418s 418s Model: quadratic 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -9.08e-01 -3.06e-01 3.08e-05 2.39e-01 7.57e-01 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -3.12e+00 9.19e-02 418s b1 -6.61e-04 1.47e-03 418s b2 5.18e-06 4.40e-06 418s 418s Residual standard error: 0.401 418s Degrees of freedom: 46 418s 418s Call: 418s lm(formula = y ~ x + I(x^2), data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -0.75741 -0.23947 -0.00003 0.30638 0.90831 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -3.118e+00 9.195e-02 -33.914 <2e-16 *** 418s x -6.612e-04 1.466e-03 -0.451 0.654 418s I(x^2) 5.175e-06 4.401e-06 1.176 0.246 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.4007 on 46 degrees of freedom 418s Multiple R-squared: 0.1193, Adjusted R-squared: 0.08097 418s F-statistic: 3.115 on 2 and 46 DF, p-value: 0.05388 418s 418s e0 b1 b2 418s e0 8.454726e-03 -7.868733e-05 1.608713e-07 418s b1 -7.868733e-05 2.149290e-06 -6.145868e-09 418s b2 1.608713e-07 -6.145868e-09 1.936461e-11 418s (Intercept) x I(x^2) 418s (Intercept) 8.454726e-03 -7.868733e-05 1.608713e-07 418s x -7.868733e-05 2.149290e-06 -6.145868e-09 418s I(x^2) 1.608713e-07 -6.145868e-09 1.936461e-11 418s $fit 418s [1] 0.49280484 0.00000000 0.05861756 0.00000000 0.25773527 0.00000000 418s [7] 0.05861756 0.00000000 0.25773527 0.05861756 0.25773527 -0.01991690 418s [13] 0.05861756 -0.01991690 0.05861756 0.02376374 0.05861756 0.05861756 418s [19] 0.02376374 0.49280484 0.00000000 0.49280484 0.00000000 0.05861756 418s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.02376374 418s [31] 0.25773527 0.00000000 0.25773527 -0.01991690 0.25773527 0.00000000 418s [37] 0.00000000 0.00000000 0.25773527 0.00000000 0.25773527 -0.01991690 418s [43] 0.25773527 0.02376374 0.05861756 -0.01991690 0.00000000 0.25773527 418s [49] 0.00000000 418s 418s $se.fit 418s [1] 0.19776187 0.00000000 0.13594191 0.00000000 0.13486241 0.00000000 418s [7] 0.13594191 0.00000000 0.13486241 0.13594191 0.13486241 0.09012454 418s [13] 0.13594191 0.09012454 0.13594191 0.13105561 0.13594191 0.13594191 418s [19] 0.13105561 0.19776187 0.00000000 0.19776187 0.00000000 0.13594191 418s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.13105561 418s [31] 0.13486241 0.00000000 0.13486241 0.09012454 0.13486241 0.00000000 418s [37] 0.00000000 0.00000000 0.13486241 0.00000000 0.13486241 0.09012454 418s [43] 0.13486241 0.13105561 0.13594191 0.09012454 0.00000000 0.13486241 418s [49] 0.00000000 418s 418s $fit 418s [1] -3.118383 -3.124477 -3.132746 418s 418s $se.fit 418s [1] 0.09194958 0.08435629 0.08409705 418s 418s $fit 418s 1 2 3 418s -3.118383 -3.124477 -3.132746 418s 418s $se.fit 418s 1 2 3 418s 0.09194958 0.08435629 0.08409705 418s 418s $df 418s [1] 46 418s 418s $residual.scale 418s [1] 0.4007027 418s 418s [1] 508.0679 418s [1] 62.95473 418s [1] 62.95473 418s Dose Response Model 418s 418s Model: quadratic 418s Fit-type: normal 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -0.87232 -0.24673 -0.00516 0.29930 0.65583 418s 418s Coefficients with approx. stand. error: 418s Estimate Std. Error 418s e0 -3.08e+00 1.69e-01 418s b1 -5.76e-04 1.59e-03 418s b2 4.82e-06 4.74e-06 418s age -1.60e-03 2.09e-03 418s centergreen -4.89e-03 2.03e-01 418s centerred 6.72e-02 1.75e-01 418s centersilver 7.81e-02 1.87e-01 418s centeryellow 9.70e-02 1.95e-01 418s 418s Residual standard error: 0.418 418s Degrees of freedom: 41 418s 418s Call: 418s lm(formula = y ~ x + I(x^2) + age + center, data = datset) 418s 418s Residuals: 418s Min 1Q Median 3Q Max 418s -0.65583 -0.29930 0.00516 0.24673 0.87232 418s 418s Coefficients: 418s Estimate Std. Error t value Pr(>|t|) 418s (Intercept) -3.076e+00 1.692e-01 -18.182 <2e-16 *** 418s x -5.756e-04 1.594e-03 -0.361 0.720 418s I(x^2) 4.822e-06 4.738e-06 1.018 0.315 418s age -1.604e-03 2.092e-03 -0.767 0.448 418s centergreen -4.891e-03 2.034e-01 -0.024 0.981 418s centerred 6.715e-02 1.753e-01 0.383 0.704 418s centersilver 7.814e-02 1.875e-01 0.417 0.679 418s centeryellow 9.700e-02 1.950e-01 0.497 0.622 418s --- 418s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 418s 418s Residual standard error: 0.4185 on 41 degrees of freedom 418s Multiple R-squared: 0.1437, Adjusted R-squared: -0.002451 418s F-statistic: 0.9832 on 7 and 41 DF, p-value: 0.4566 418s 418s e0 b1 b2 age 418s e0 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 418s b1 -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 418s b2 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 418s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 418s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 418s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 418s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 418s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 418s centergreen centerred centersilver centeryellow 418s e0 -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 418s b1 -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 418s b2 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 418s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 418s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 418s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 418s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 418s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 418s (Intercept) x I(x^2) age 418s (Intercept) 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 418s x -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 418s I(x^2) 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 418s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 418s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 418s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 418s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 418s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 418s centergreen centerred centersilver centeryellow 418s (Intercept) -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 418s x -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 418s I(x^2) 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 418s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 418s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 418s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 418s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 418s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 418s $fit 418s [1] -3.124527 -3.129801 -3.133870 418s 418s $se.fit 418s [1] 0.1418548 0.1377349 0.1475950 418s 418s $fit 418s 1 2 3 418s -3.124527 -3.129801 -3.133870 418s 418s $se.fit 418s 1 2 3 418s 0.1418548 0.1377349 0.1475950 418s 418s $df 418s [1] 41 418s 418s $residual.scale 418s [1] 0.418494 418s 418s [1] 215.5724 418s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 0 0Warning message: 418s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 418s mns is not a numeric but a array, converting with as.numeric() 418s Warning message: 418s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 418s mns is not a numeric but a array, converting with as.numeric() 418s Warning message: 418s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 418s mns is not a numeric but a array, converting with as.numeric() 418s 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418s [1] 0 0 0 0 0 418s [1] 0 0 0 0 0 418s e0 delta 418s 0.47569910 0.02447331 418s e0 delta 418s 0.47569910 0.02447331 418s Warning message: 418s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 418s mns is not a numeric but a array, converting with as.numeric() 418s testsFitting.R passed 418s Loading required package: DoseFinding 421s testsMCPMod.R passed 421s Loading required package: DoseFinding 422s Loading required package: multcomp 422s Loading required package: mvtnorm 422s Loading required package: survival 423s Loading required package: TH.data 423s Loading required package: MASS 423s 423s Attaching package: ‘TH.data’ 423s 423s The following object is masked from ‘package:MASS’: 423s 423s geyser 423s 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 424s 424s Linear Hypotheses: 424s Estimate Std. Error t value Pr(>t) 424s linear <= 0 0.07260 0.05755 1.262 0.1756 424s betaMod <= 0 0.12179 0.05559 2.191 0.0287 * 424s sigEmax <= 0 0.08677 0.05648 1.536 0.1114 424s --- 424s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear betaMod sigEmax 424s 0 -0.472 -0.492 -0.349 424s 172 -0.391 -0.345 -0.489 424s 285 -0.132 0.032 -0.240 424s 516 0.262 0.799 0.503 424s 761 0.733 0.007 0.574 424s 424s Contrast Correlation: 424s linear betaMod sigEmax 424s linear 1.000 0.645 0.942 424s betaMod 0.645 1.000 0.741 424s sigEmax 0.942 0.741 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s betaMod 2.191 0.0287 424s sigEmax 1.536 0.1112 424s linear 1.262 0.1757 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: lm(formula = y ~ x, data = dd2) 424s 424s Linear Hypotheses: 424s Estimate Std. Error t value Pr(>t) 424s linear <= 0 0.07985 0.05691 1.403 0.1404 424s betaMod <= 0 0.11839 0.05507 2.150 0.0314 * 424s sigEmax <= 0 0.09407 0.05594 1.682 0.0853 . 424s --- 424s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear betaMod sigEmax 424s 0 -0.472 -0.487 -0.347 424s 172 -0.389 -0.348 -0.490 424s 285 -0.132 0.030 -0.239 424s 516 0.255 0.800 0.500 424s 761 0.738 0.005 0.576 424s 424s Contrast Correlation: 424s linear betaMod sigEmax 424s linear 1.000 0.642 0.941 424s betaMod 0.642 1.000 0.740 424s sigEmax 0.941 0.740 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s betaMod 2.150 0.0317 424s sigEmax 1.682 0.0852 424s linear 1.403 0.1403 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 424s 424s Linear Hypotheses: 424s Estimate Std. Error t value Pr(>t) 424s linlog <= 0 0.09114 0.05971 1.526 0.1510 424s logistic1 <= 0 0.10293 0.05761 1.787 0.0940 . 424s logistic2 <= 0 0.09583 0.05707 1.679 0.1154 424s exponential <= 0 0.02544 0.05514 0.461 0.5623 424s quadratic <= 0 0.11676 0.05980 1.952 0.0674 . 424s --- 424s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linlog logistic1 logistic2 exponential quadratic 424s 0 -0.624 -0.448 -0.457 -0.268 -0.665 424s 172 -0.309 -0.590 -0.475 -0.347 -0.055 424s 285 -0.049 0.101 -0.118 -0.191 0.199 424s 516 0.366 0.500 0.499 -0.069 0.696 424s 761 0.616 0.437 0.550 0.875 -0.174 424s 424s Contrast Correlation: 424s linlog logistic1 logistic2 exponential quadratic 424s linlog 1.000 0.902 0.955 0.799 0.651 424s logistic1 0.902 1.000 0.949 0.671 0.660 424s logistic2 0.955 0.949 1.000 0.792 0.586 424s exponential 0.799 0.671 0.792 1.000 0.063 424s quadratic 0.651 0.660 0.586 0.063 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s quadratic 1.952 0.0675 424s logistic1 1.787 0.0941 424s logistic2 1.679 0.1154 424s linlog 1.526 0.1506 424s exponential 0.461 0.5625 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: lm(formula = y ~ x, data = dd2) 424s 424s Linear Hypotheses: 424s Estimate Std. Error t value Pr(>t) 424s linlog <= 0 0.09484 0.05913 1.604 0.1320 424s logistic1 <= 0 0.10608 0.05706 1.859 0.0817 . 424s logistic2 <= 0 0.10119 0.05654 1.790 0.0928 . 424s exponential <= 0 0.03666 0.05440 0.674 0.4665 424s quadratic <= 0 0.10792 0.05938 1.817 0.0885 . 424s --- 424s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linlog logistic1 logistic2 exponential quadratic 424s 0 -0.623 -0.445 -0.455 -0.270 -0.664 424s 172 -0.307 -0.592 -0.476 -0.342 -0.056 424s 285 -0.050 0.101 -0.118 -0.189 0.197 424s 516 0.358 0.497 0.496 -0.076 0.698 424s 761 0.622 0.440 0.554 0.877 -0.175 424s 424s Contrast Correlation: 424s linlog logistic1 logistic2 exponential quadratic 424s linlog 1.000 0.901 0.955 0.800 0.648 424s logistic1 0.901 1.000 0.949 0.670 0.658 424s logistic2 0.955 0.949 1.000 0.792 0.584 424s exponential 0.800 0.670 0.792 1.000 0.062 424s quadratic 0.648 0.658 0.584 0.062 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s logistic1 1.859 0.0816 424s quadratic 1.817 0.0887 424s logistic2 1.790 0.0933 424s linlog 1.604 0.1316 424s exponential 0.674 0.4667 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: lm(formula = y ~ x, data = dd2) 424s 424s Linear Hypotheses: 424s Estimate Std. Error t value Pr(>t) 424s linlog <= 0 -0.2995 1.0212 -0.293 0.821 424s logistic1 <= 0 -0.1795 0.9837 -0.182 0.785 424s logistic2 <= 0 -0.1401 0.9877 -0.142 0.771 424s exponential <= 0 -0.2892 0.9568 -0.302 0.823 424s quadratic <= 0 -0.1973 1.2830 -0.154 0.776 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linlog logistic1 logistic2 exponential quadratic 424s 0 -0.464 -0.268 -0.289 -0.207 -0.751 424s 124 -0.436 -0.627 -0.556 -0.450 -0.241 424s 272 0.013 -0.006 -0.083 -0.187 0.476 424s 560 0.127 0.196 0.172 -0.004 0.353 424s 865 0.761 0.705 0.755 0.848 0.164 424s 424s Contrast Correlation: 424s linlog logistic1 logistic2 exponential quadratic 424s linlog 1.000 0.950 0.963 0.890 0.665 424s logistic1 0.950 1.000 0.992 0.879 0.591 424s logistic2 0.963 0.992 1.000 0.922 0.542 424s exponential 0.890 0.879 0.922 1.000 0.252 424s quadratic 0.665 0.591 0.542 0.252 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s logistic2 -0.142 0.771 424s quadratic -0.154 0.776 424s logistic1 -0.182 0.785 424s linlog -0.293 0.821 424s exponential -0.302 0.823 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 424s 424s Linear Hypotheses: 424s Estimate Std. Error z value Pr(>z) 424s linear <= 0 0.19645 0.33561 0.585 0.395 424s betaMod <= 0 0.03813 0.31565 0.121 0.587 424s sigEmax <= 0 0.30472 0.34592 0.881 0.283 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear betaMod sigEmax 424s 0 -0.794 -0.793 -0.774 424s 190 -0.064 -0.022 -0.192 424s 344 0.197 0.577 0.317 424s 404 0.098 0.190 0.163 424s 616 0.563 0.048 0.487 424s 424s Contrast Correlation: 424s linear betaMod sigEmax 424s linear 1.000 0.723 0.962 424s betaMod 0.723 1.000 0.793 424s sigEmax 0.962 0.793 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s sigEmax 0.881 0.283 424s linear 0.585 0.395 424s betaMod 0.121 0.587 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 424s 424s Linear Hypotheses: 424s Estimate Std. Error z value Pr(>z) 424s linear <= 0 0.2547 0.1877 1.357 0.1500 424s betaMod <= 0 0.2367 0.2371 0.999 0.2555 424s sigEmax <= 0 0.3698 0.1889 1.958 0.0476 * 424s --- 424s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear betaMod sigEmax 424s 0 0.418 0.634 0.310 424s 68.5 0.114 0.150 0.139 424s 85.9 0.387 0.362 0.551 424s 166 0.027 -0.572 -0.033 424s 197 -0.015 -0.158 -0.054 424s 278 -0.129 -0.264 -0.172 424s 332 -0.803 -0.152 -0.740 424s 424s Contrast Correlation: 424s linear betaMod sigEmax 424s linear 1.000 0.635 0.967 424s betaMod 0.635 1.000 0.677 424s sigEmax 0.967 0.677 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s sigEmax 1.958 0.0477 424s linear 1.357 0.1501 424s betaMod 0.999 0.2556 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 424s 424s Linear Hypotheses: 424s Estimate Std. Error z value Pr(>z) 424s linear <= 0 0.3391 0.3218 1.054 0.226 424s betaMod <= 0 0.3556 0.3124 1.138 0.201 424s sigEmax <= 0 0.2935 0.3497 0.839 0.299 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear betaMod sigEmax 424s 0 -0.721 -0.796 -0.547 424s 79.1 -0.129 -0.102 -0.312 424s 117 0.005 0.106 -0.137 424s 208 0.191 0.519 0.288 424s 398 0.654 0.274 0.708 424s 424s Contrast Correlation: 424s linear betaMod sigEmax 424s linear 1.000 0.785 0.954 424s betaMod 0.785 1.000 0.742 424s sigEmax 0.954 0.742 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s betaMod 1.138 0.201 424s linear 1.054 0.226 424s sigEmax 0.839 0.299 424s Warning message: 424s In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 424s Warning from mvtnorm::pmvt: univariate: using pnorm. 424s 424s Simultaneous Tests for General Linear Hypotheses 424s 424s Multiple Comparisons of Means: User-defined Contrasts 424s 424s 424s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 424s 424s Linear Hypotheses: 424s Estimate Std. Error z value Pr(>z) 424s linear <= 0 0.3391 0.3218 1.054 0.146 424s (Adjusted p values reported -- single-step method) 424s 424s Multiple Contrast Test 424s 424s Contrasts: 424s linear 424s 0 -0.721 424s 79.1 -0.129 424s 117 0.005 424s 208 0.191 424s 398 0.654 424s 424s Contrast Correlation: 424s linear 424s linear 1 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s linear 1.054 0.146 424s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 424s Dose Response Model 424s 424s Model: sigEmax 424s Fit-type: general 424s 424s Coefficients dose-response model 424s eMax ed50 h 424s 0.4714 0.4880 0.5000 424s 424s Fitted to: 424s 1 2 3 4 424s 0.2846 0.2965 0.3502 0.3480 424s 424s Generalized residual sum of squares: 0.07825 424s Multiple Contrast Test 424s 424s Contrasts: 424s emax linear logistic linInt 424s 1 0.462Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 424s -0.429 0.511 -0.672 424s 2 0.505 0.002 0.507 0.437 424s 3 0.504 0.400 0.485 0.418 424s 4 0.527 0.810 0.497 0.428 424s 424s Contrast Correlation: 424s emax linear logistic linInt 424s emax 1.000 0.715 1.000 0.617 424s linear 0.715 1.000 0.698 0.863 424s logistic 1.000 0.698 1.000 0.598 424s linInt 0.617 0.863 0.598 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s emax 3.178 0.00193 424s logistic 3.164 0.00194 424s linear 2.640 0.00968 424s linInt 2.247 0.02721 424s Dose Response Model 424s 424s Model: sigEmax 424s Fit-type: general 424s 424s Coefficients dose-response model 424s eMax ed50 h 424s 0.4714 0.4880 0.5000 424s 424s Fitted to: 424s 3 4 1 2 424s 0.3502 0.3480 0.2846 0.2965 424s 424s Generalized residual sum of squares: 0.07825 424s Multiple Contrast Test 424s 424s Contrasts: 424s emax linear logistic linInt 424s 1 0.462 -0.429 0.511 -0.672 424s 2 0.505 0.002 0.507 0.437 424s 3 0.504 0.400 0.485 0.418 424s 4 0.527 0.810 0.497 0.428 424s 424s Contrast Correlation: 424s emax linear logistic linInt 424s emax 1.000 0.715 1.000 0.617 424s linear 0.715 1.000 0.698 0.863 424s logistic 1.000 0.698 1.000 0.598 424s linInt Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 424s 0.617 0.863 0.598 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s emax 3.178 0.00213 424s logistic 3.164 0.00174 424s linear 2.640 0.00941 424s linInt 2.247 0.02663 424s Dose Response Model 424s 424s Model: sigEmax 424s Fit-type: general 424s 424s Coefficients dose-response model 424s e0 eMax ed50 h 424s 0.2171 0.4714 0.4860 0.5000 424s 424s Fitted to: 424s 0 1 2 3 4 424s 0.2169 0.5016 0.5138 0.5677 0.5648 424s 424s Generalized residual sum of squares: 0.07892 424s Multiple Contrast Test 424s 424s Contrasts: 424s emax linear logistic linInt 424s 0 -0.894 -0.617 -0.894 -0.522 424s 1 0.207 -0.338 0.228 -0.573 424s 2 0.226 0.002 0.227 0.373 424s 3 0.227 0.315 0.218 0.358 424s 4 0.235 0.637 0.221 0.363 424s 424s Contrast Correlation: 424s emax linear logistic linInt 424s emax 1.000 0.715 1.000 0.618 424s linear 0.715 1.000 0.698 0.863 424s logistic 1.000 0.698 1.000 0.599 424s linInt 0.618 0.863 0.599 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s emax 3.186 0.00184 424s logistic 3.172 0.00177 424s linear 2.645 0.00956 424s linInt 2.254 0.02649 424s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 424s Dose Response Model 424s 424s Model: sigEmax 424s Fit-type: general 424s 424s Coefficients dose-response model 424s e0 eMax ed50 h 424s 0.2171 0.4714 0.4860 0.5000 424s 424s Fitted to: 424s 2 3 0 1 4 424s 0.5138 0.5677 0.2169 0.5016 0.5648 424s 424s Generalized residual sum of squares: 0.07892 424s Multiple Contrast Test 424s 424s Contrasts: 424s emax linear logistic linInt 424s 0 -0.894 -0.617 -0.894 -0.522 424s 1 0.207 -0.338 0.228 -0.573 424s 2 0.226 0.002 0.227 0.373 424s 3 0.227 0.315 0.218 0.358 424s 4 0.235 0.637 0.221 0.363 424s 424s Contrast Correlation: 424s emax linear logistic linInt 424s emax 1.000 0.715 1.000 0.618 424s linear 0.715 1.000 0.698 0.863 424s logistic 1.000 0.698 1.000 0.599 424s linInt 0.618 0.863 0.599 1.000 424s 424s Multiple Contrast Test: 424s t-Stat adj-p 424s emax 3.186 0.00163 424s logistic 3.172 0.00192 424s linear 2.645 0.00981 424s linInt 2.254 0.02699 424s Warning messages: 424s 1: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 424s Warning from mvtnorm::pmvt: Covariance matrix not positive semidefinite. 424s 2: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 424s Setting calculated p-value to NA 424s [1] TRUE 424s testsMCT.R passed 425s Loading required package: DoseFinding 425s Loading required package: quadprog 425s Loading required package: Rsolnp 425s testsoptContr.R passed 425s testsplotDRMod.R consists only from comments and returns non-zero exit value ... ignored 426s testssampSize.R passed 426s Loading required package: DoseFinding 428s [1] 0.3076509 428s [1] 0.6153019 428s [1] 0.9229528 428s [1] 2.673503 428s [1] 0.7028559 428s [1] 2.064397 428s [1] NA 429s testssamplMod.R passed 430s /usr/bin/xdg-open: 1032: www-browser: not found 430s /usr/bin/xdg-open: 1032: links2: not found 430s /usr/bin/xdg-open: 1032: elinks: not found 430s /usr/bin/xdg-open: 1032: links: not found 430s /usr/bin/xdg-open: 1032: lynx: not found 430s /usr/bin/xdg-open: 1032: w3m: not found 430s xdg-open: no method available for opening 'https://huisophiesunrshiny.shinyapps.io/designmcpmod/' 431s [ FAIL 0 | WARN 0 | SKIP 0 | PASS 53 ] 431s testthat.R passed 431s autopkgtest [15:30:58]: test run-unit-test: -----------------------] 432s autopkgtest [15:30:59]: test run-unit-test: - - - - - - - - - - results - - - - - - - - - - 432s run-unit-test PASS 433s autopkgtest [15:31:00]: test pkg-r-autopkgtest: preparing testbed 433s Reading package lists... 433s Building dependency tree... 433s Reading state information... 434s Starting pkgProblemResolver with broken count: 0 434s Starting 2 pkgProblemResolver with broken count: 0 434s Done 435s The following NEW packages will be installed: 435s build-essential cpp cpp-14 cpp-14-aarch64-linux-gnu cpp-aarch64-linux-gnu 435s dctrl-tools g++ g++-14 g++-14-aarch64-linux-gnu g++-aarch64-linux-gnu gcc 435s gcc-14 gcc-14-aarch64-linux-gnu gcc-aarch64-linux-gnu gfortran gfortran-14 435s gfortran-14-aarch64-linux-gnu gfortran-aarch64-linux-gnu icu-devtools 435s libasan8 libblas-dev libbz2-dev libcc1-0 libdeflate-dev libgcc-14-dev 435s libgfortran-14-dev libhwasan0 libicu-dev libisl23 libitm1 libjpeg-dev 435s libjpeg-turbo8-dev libjpeg8-dev liblapack-dev liblsan0 liblzma-dev libmpc3 435s libncurses-dev libpcre2-16-0 libpcre2-32-0 libpcre2-dev libpcre2-posix3 435s libpkgconf3 libpng-dev libreadline-dev libstdc++-14-dev libtirpc-dev 435s libtsan2 libubsan1 pkg-r-autopkgtest pkgconf pkgconf-bin r-base-dev 435s zlib1g-dev 435s 0 upgraded, 54 newly installed, 0 to remove and 0 not upgraded. 435s Need to get 92.7 MB of archives. 435s After this operation, 334 MB of additional disk space will be used. 435s Get:1 http://ftpmaster.internal/ubuntu plucky/main arm64 libisl23 arm64 0.27-1 [676 kB] 436s Get:2 http://ftpmaster.internal/ubuntu plucky/main arm64 libmpc3 arm64 1.3.1-1build2 [56.8 kB] 437s Get:3 http://ftpmaster.internal/ubuntu plucky/main arm64 cpp-14-aarch64-linux-gnu arm64 14.2.0-17ubuntu3 [10.6 MB] 448s Get:4 http://ftpmaster.internal/ubuntu plucky/main arm64 cpp-14 arm64 14.2.0-17ubuntu3 [1028 B] 448s Get:5 http://ftpmaster.internal/ubuntu plucky/main arm64 cpp-aarch64-linux-gnu arm64 4:14.2.0-1ubuntu1 [5558 B] 448s Get:6 http://ftpmaster.internal/ubuntu plucky/main arm64 cpp arm64 4:14.2.0-1ubuntu1 [22.4 kB] 448s Get:7 http://ftpmaster.internal/ubuntu plucky/main arm64 libcc1-0 arm64 15-20250222-0ubuntu1 [44.2 kB] 448s Get:8 http://ftpmaster.internal/ubuntu plucky/main arm64 libitm1 arm64 15-20250222-0ubuntu1 [28.0 kB] 448s Get:9 http://ftpmaster.internal/ubuntu plucky/main arm64 libasan8 arm64 15-20250222-0ubuntu1 [2924 kB] 451s Get:10 http://ftpmaster.internal/ubuntu plucky/main arm64 liblsan0 arm64 15-20250222-0ubuntu1 [1319 kB] 453s Get:11 http://ftpmaster.internal/ubuntu plucky/main arm64 libtsan2 arm64 15-20250222-0ubuntu1 [2694 kB] 456s Get:12 http://ftpmaster.internal/ubuntu plucky/main arm64 libubsan1 arm64 15-20250222-0ubuntu1 [1178 kB] 458s Get:13 http://ftpmaster.internal/ubuntu plucky/main arm64 libhwasan0 arm64 15-20250222-0ubuntu1 [1642 kB] 459s Get:14 http://ftpmaster.internal/ubuntu plucky/main arm64 libgcc-14-dev arm64 14.2.0-17ubuntu3 [2593 kB] 462s Get:15 http://ftpmaster.internal/ubuntu plucky/main arm64 gcc-14-aarch64-linux-gnu arm64 14.2.0-17ubuntu3 [20.9 MB] 486s Get:16 http://ftpmaster.internal/ubuntu plucky/main arm64 gcc-14 arm64 14.2.0-17ubuntu3 [526 kB] 486s Get:17 http://ftpmaster.internal/ubuntu plucky/main arm64 gcc-aarch64-linux-gnu arm64 4:14.2.0-1ubuntu1 [1200 B] 486s Get:18 http://ftpmaster.internal/ubuntu plucky/main arm64 gcc arm64 4:14.2.0-1ubuntu1 [4998 B] 486s Get:19 http://ftpmaster.internal/ubuntu plucky/main arm64 libstdc++-14-dev arm64 14.2.0-17ubuntu3 [2499 kB] 489s Get:20 http://ftpmaster.internal/ubuntu plucky/main arm64 g++-14-aarch64-linux-gnu arm64 14.2.0-17ubuntu3 [12.1 MB] 502s Get:21 http://ftpmaster.internal/ubuntu plucky/main arm64 g++-14 arm64 14.2.0-17ubuntu3 [21.8 kB] 502s Get:22 http://ftpmaster.internal/ubuntu plucky/main arm64 g++-aarch64-linux-gnu arm64 4:14.2.0-1ubuntu1 [956 B] 502s Get:23 http://ftpmaster.internal/ubuntu plucky/main arm64 g++ arm64 4:14.2.0-1ubuntu1 [1080 B] 502s Get:24 http://ftpmaster.internal/ubuntu plucky/main arm64 build-essential arm64 12.10ubuntu1 [4932 B] 502s Get:25 http://ftpmaster.internal/ubuntu plucky/main arm64 dctrl-tools arm64 2.24-3build3 [103 kB] 502s Get:26 http://ftpmaster.internal/ubuntu plucky/main arm64 libgfortran-14-dev arm64 14.2.0-17ubuntu3 [498 kB] 503s Get:27 http://ftpmaster.internal/ubuntu plucky/main arm64 gfortran-14-aarch64-linux-gnu arm64 14.2.0-17ubuntu3 [11.4 MB] 515s Get:28 http://ftpmaster.internal/ubuntu plucky/main arm64 gfortran-14 arm64 14.2.0-17ubuntu3 [13.6 kB] 515s Get:29 http://ftpmaster.internal/ubuntu plucky/main arm64 gfortran-aarch64-linux-gnu arm64 4:14.2.0-1ubuntu1 [1022 B] 515s Get:30 http://ftpmaster.internal/ubuntu plucky/main arm64 gfortran arm64 4:14.2.0-1ubuntu1 [1166 B] 515s Get:31 http://ftpmaster.internal/ubuntu plucky/main arm64 icu-devtools arm64 76.1-1ubuntu2 [213 kB] 515s Get:32 http://ftpmaster.internal/ubuntu plucky/main arm64 libblas-dev arm64 3.12.1-2 [126 kB] 516s Get:33 http://ftpmaster.internal/ubuntu plucky/main arm64 libbz2-dev arm64 1.0.8-6 [36.1 kB] 516s Get:34 http://ftpmaster.internal/ubuntu plucky/main arm64 libdeflate-dev arm64 1.23-1 [53.7 kB] 516s Get:35 http://ftpmaster.internal/ubuntu plucky/main arm64 libicu-dev arm64 76.1-1ubuntu2 [12.2 MB] 528s Get:36 http://ftpmaster.internal/ubuntu plucky/main arm64 libjpeg-turbo8-dev arm64 2.1.5-3ubuntu2 [306 kB] 529s Get:37 http://ftpmaster.internal/ubuntu plucky/main arm64 libjpeg8-dev arm64 8c-2ubuntu11 [1484 B] 529s Get:38 http://ftpmaster.internal/ubuntu plucky/main arm64 libjpeg-dev arm64 8c-2ubuntu11 [1482 B] 529s Get:39 http://ftpmaster.internal/ubuntu plucky/main arm64 liblapack-dev arm64 3.12.1-2 [4439 kB] 534s Get:40 http://ftpmaster.internal/ubuntu plucky/main arm64 libncurses-dev arm64 6.5+20250216-2 [389 kB] 534s Get:41 http://ftpmaster.internal/ubuntu plucky/main arm64 libpcre2-16-0 arm64 10.45-1 [222 kB] 534s Get:42 http://ftpmaster.internal/ubuntu plucky/main arm64 libpcre2-32-0 arm64 10.45-1 [210 kB] 535s Get:43 http://ftpmaster.internal/ubuntu plucky/main arm64 libpcre2-posix3 arm64 10.45-1 [7084 B] 535s Get:44 http://ftpmaster.internal/ubuntu plucky/main arm64 libpcre2-dev arm64 10.45-1 [768 kB] 536s Get:45 http://ftpmaster.internal/ubuntu plucky/main arm64 libpkgconf3 arm64 1.8.1-4 [31.4 kB] 536s Get:46 http://ftpmaster.internal/ubuntu plucky/main arm64 zlib1g-dev arm64 1:1.3.dfsg+really1.3.1-1ubuntu1 [894 kB] 537s Get:47 http://ftpmaster.internal/ubuntu plucky/main arm64 libpng-dev arm64 1.6.47-1 [269 kB] 537s Get:48 http://ftpmaster.internal/ubuntu plucky/main arm64 libreadline-dev arm64 8.2-6 [179 kB] 537s Get:49 http://ftpmaster.internal/ubuntu plucky/main arm64 liblzma-dev arm64 5.6.4-1 [180 kB] 537s Get:50 http://ftpmaster.internal/ubuntu plucky/main arm64 pkgconf-bin arm64 1.8.1-4 [20.9 kB] 537s Get:51 http://ftpmaster.internal/ubuntu plucky/main arm64 pkgconf arm64 1.8.1-4 [16.7 kB] 537s Get:52 http://ftpmaster.internal/ubuntu plucky/main arm64 libtirpc-dev arm64 1.3.4+ds-1.3 [201 kB] 538s Get:53 http://ftpmaster.internal/ubuntu plucky/universe arm64 r-base-dev all 4.4.3-1 [4176 B] 538s Get:54 http://ftpmaster.internal/ubuntu plucky/universe arm64 pkg-r-autopkgtest all 20231212ubuntu1 [6448 B] 538s Fetched 92.7 MB in 1min 43s (904 kB/s) 538s Selecting previously unselected package libisl23:arm64. 538s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 99319 files and directories currently installed.) 538s Preparing to unpack .../00-libisl23_0.27-1_arm64.deb ... 538s Unpacking libisl23:arm64 (0.27-1) ... 539s Selecting previously unselected package libmpc3:arm64. 539s Preparing to unpack .../01-libmpc3_1.3.1-1build2_arm64.deb ... 539s Unpacking libmpc3:arm64 (1.3.1-1build2) ... 539s Selecting previously unselected package cpp-14-aarch64-linux-gnu. 539s Preparing to unpack .../02-cpp-14-aarch64-linux-gnu_14.2.0-17ubuntu3_arm64.deb ... 539s Unpacking cpp-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 539s Selecting previously unselected package cpp-14. 539s Preparing to unpack .../03-cpp-14_14.2.0-17ubuntu3_arm64.deb ... 539s Unpacking cpp-14 (14.2.0-17ubuntu3) ... 539s Selecting previously unselected package cpp-aarch64-linux-gnu. 539s Preparing to unpack .../04-cpp-aarch64-linux-gnu_4%3a14.2.0-1ubuntu1_arm64.deb ... 539s Unpacking cpp-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 539s Selecting previously unselected package cpp. 539s Preparing to unpack .../05-cpp_4%3a14.2.0-1ubuntu1_arm64.deb ... 539s Unpacking cpp (4:14.2.0-1ubuntu1) ... 539s Selecting previously unselected package libcc1-0:arm64. 539s Preparing to unpack .../06-libcc1-0_15-20250222-0ubuntu1_arm64.deb ... 539s Unpacking libcc1-0:arm64 (15-20250222-0ubuntu1) ... 539s Selecting previously unselected package libitm1:arm64. 539s Preparing to unpack .../07-libitm1_15-20250222-0ubuntu1_arm64.deb ... 539s Unpacking libitm1:arm64 (15-20250222-0ubuntu1) ... 539s Selecting previously unselected package libasan8:arm64. 539s Preparing to unpack .../08-libasan8_15-20250222-0ubuntu1_arm64.deb ... 539s Unpacking libasan8:arm64 (15-20250222-0ubuntu1) ... 539s Selecting previously unselected package liblsan0:arm64. 539s Preparing to unpack .../09-liblsan0_15-20250222-0ubuntu1_arm64.deb ... 539s Unpacking liblsan0:arm64 (15-20250222-0ubuntu1) ... 539s Selecting previously unselected package libtsan2:arm64. 539s Preparing to unpack .../10-libtsan2_15-20250222-0ubuntu1_arm64.deb ... 539s Unpacking libtsan2:arm64 (15-20250222-0ubuntu1) ... 540s Selecting previously unselected package libubsan1:arm64. 540s Preparing to unpack .../11-libubsan1_15-20250222-0ubuntu1_arm64.deb ... 540s Unpacking libubsan1:arm64 (15-20250222-0ubuntu1) ... 540s Selecting previously unselected package libhwasan0:arm64. 540s Preparing to unpack .../12-libhwasan0_15-20250222-0ubuntu1_arm64.deb ... 540s Unpacking libhwasan0:arm64 (15-20250222-0ubuntu1) ... 540s Selecting previously unselected package libgcc-14-dev:arm64. 540s Preparing to unpack .../13-libgcc-14-dev_14.2.0-17ubuntu3_arm64.deb ... 540s Unpacking libgcc-14-dev:arm64 (14.2.0-17ubuntu3) ... 540s Selecting previously unselected package gcc-14-aarch64-linux-gnu. 540s Preparing to unpack .../14-gcc-14-aarch64-linux-gnu_14.2.0-17ubuntu3_arm64.deb ... 540s Unpacking gcc-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 541s Selecting previously unselected package gcc-14. 541s Preparing to unpack .../15-gcc-14_14.2.0-17ubuntu3_arm64.deb ... 541s Unpacking gcc-14 (14.2.0-17ubuntu3) ... 541s Selecting previously unselected package gcc-aarch64-linux-gnu. 541s Preparing to unpack .../16-gcc-aarch64-linux-gnu_4%3a14.2.0-1ubuntu1_arm64.deb ... 541s Unpacking gcc-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 541s Selecting previously unselected package gcc. 541s Preparing to unpack .../17-gcc_4%3a14.2.0-1ubuntu1_arm64.deb ... 541s Unpacking gcc (4:14.2.0-1ubuntu1) ... 541s Selecting previously unselected package libstdc++-14-dev:arm64. 541s Preparing to unpack .../18-libstdc++-14-dev_14.2.0-17ubuntu3_arm64.deb ... 541s Unpacking libstdc++-14-dev:arm64 (14.2.0-17ubuntu3) ... 541s Selecting previously unselected package g++-14-aarch64-linux-gnu. 541s Preparing to unpack .../19-g++-14-aarch64-linux-gnu_14.2.0-17ubuntu3_arm64.deb ... 541s Unpacking g++-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 541s Selecting previously unselected package g++-14. 541s Preparing to unpack .../20-g++-14_14.2.0-17ubuntu3_arm64.deb ... 541s Unpacking g++-14 (14.2.0-17ubuntu3) ... 541s Selecting previously unselected package g++-aarch64-linux-gnu. 541s Preparing to unpack .../21-g++-aarch64-linux-gnu_4%3a14.2.0-1ubuntu1_arm64.deb ... 541s Unpacking g++-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 541s Selecting previously unselected package g++. 541s Preparing to unpack .../22-g++_4%3a14.2.0-1ubuntu1_arm64.deb ... 541s Unpacking g++ (4:14.2.0-1ubuntu1) ... 542s Selecting previously unselected package build-essential. 542s Preparing to unpack .../23-build-essential_12.10ubuntu1_arm64.deb ... 542s Unpacking build-essential (12.10ubuntu1) ... 542s Selecting previously unselected package dctrl-tools. 542s Preparing to unpack .../24-dctrl-tools_2.24-3build3_arm64.deb ... 542s Unpacking dctrl-tools (2.24-3build3) ... 542s Selecting previously unselected package libgfortran-14-dev:arm64. 542s Preparing to unpack .../25-libgfortran-14-dev_14.2.0-17ubuntu3_arm64.deb ... 542s Unpacking libgfortran-14-dev:arm64 (14.2.0-17ubuntu3) ... 542s Selecting previously unselected package gfortran-14-aarch64-linux-gnu. 542s Preparing to unpack .../26-gfortran-14-aarch64-linux-gnu_14.2.0-17ubuntu3_arm64.deb ... 542s Unpacking gfortran-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 542s Selecting previously unselected package gfortran-14. 542s Preparing to unpack .../27-gfortran-14_14.2.0-17ubuntu3_arm64.deb ... 542s Unpacking gfortran-14 (14.2.0-17ubuntu3) ... 542s Selecting previously unselected package gfortran-aarch64-linux-gnu. 542s Preparing to unpack .../28-gfortran-aarch64-linux-gnu_4%3a14.2.0-1ubuntu1_arm64.deb ... 542s Unpacking gfortran-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 542s Selecting previously unselected package gfortran. 542s Preparing to unpack .../29-gfortran_4%3a14.2.0-1ubuntu1_arm64.deb ... 542s Unpacking gfortran (4:14.2.0-1ubuntu1) ... 542s Selecting previously unselected package icu-devtools. 542s Preparing to unpack .../30-icu-devtools_76.1-1ubuntu2_arm64.deb ... 542s Unpacking icu-devtools (76.1-1ubuntu2) ... 542s Selecting previously unselected package libblas-dev:arm64. 542s Preparing to unpack .../31-libblas-dev_3.12.1-2_arm64.deb ... 542s Unpacking libblas-dev:arm64 (3.12.1-2) ... 542s Selecting previously unselected package libbz2-dev:arm64. 542s Preparing to unpack .../32-libbz2-dev_1.0.8-6_arm64.deb ... 542s Unpacking libbz2-dev:arm64 (1.0.8-6) ... 542s Selecting previously unselected package libdeflate-dev:arm64. 542s Preparing to unpack .../33-libdeflate-dev_1.23-1_arm64.deb ... 542s Unpacking libdeflate-dev:arm64 (1.23-1) ... 543s Selecting previously unselected package libicu-dev:arm64. 543s Preparing to unpack .../34-libicu-dev_76.1-1ubuntu2_arm64.deb ... 543s Unpacking libicu-dev:arm64 (76.1-1ubuntu2) ... 543s Selecting previously unselected package libjpeg-turbo8-dev:arm64. 543s Preparing to unpack .../35-libjpeg-turbo8-dev_2.1.5-3ubuntu2_arm64.deb ... 543s Unpacking libjpeg-turbo8-dev:arm64 (2.1.5-3ubuntu2) ... 543s Selecting previously unselected package libjpeg8-dev:arm64. 543s Preparing to unpack .../36-libjpeg8-dev_8c-2ubuntu11_arm64.deb ... 543s Unpacking libjpeg8-dev:arm64 (8c-2ubuntu11) ... 543s Selecting previously unselected package libjpeg-dev:arm64. 543s Preparing to unpack .../37-libjpeg-dev_8c-2ubuntu11_arm64.deb ... 543s Unpacking libjpeg-dev:arm64 (8c-2ubuntu11) ... 543s Selecting previously unselected package liblapack-dev:arm64. 543s Preparing to unpack .../38-liblapack-dev_3.12.1-2_arm64.deb ... 543s Unpacking liblapack-dev:arm64 (3.12.1-2) ... 543s Selecting previously unselected package libncurses-dev:arm64. 543s Preparing to unpack .../39-libncurses-dev_6.5+20250216-2_arm64.deb ... 543s Unpacking libncurses-dev:arm64 (6.5+20250216-2) ... 543s Selecting previously unselected package libpcre2-16-0:arm64. 543s Preparing to unpack .../40-libpcre2-16-0_10.45-1_arm64.deb ... 543s Unpacking libpcre2-16-0:arm64 (10.45-1) ... 544s Selecting previously unselected package libpcre2-32-0:arm64. 544s Preparing to unpack .../41-libpcre2-32-0_10.45-1_arm64.deb ... 544s Unpacking libpcre2-32-0:arm64 (10.45-1) ... 544s Selecting previously unselected package libpcre2-posix3:arm64. 544s Preparing to unpack .../42-libpcre2-posix3_10.45-1_arm64.deb ... 544s Unpacking libpcre2-posix3:arm64 (10.45-1) ... 544s Selecting previously unselected package libpcre2-dev:arm64. 544s Preparing to unpack .../43-libpcre2-dev_10.45-1_arm64.deb ... 544s Unpacking libpcre2-dev:arm64 (10.45-1) ... 544s Selecting previously unselected package libpkgconf3:arm64. 544s Preparing to unpack .../44-libpkgconf3_1.8.1-4_arm64.deb ... 544s Unpacking libpkgconf3:arm64 (1.8.1-4) ... 544s Selecting previously unselected package zlib1g-dev:arm64. 544s Preparing to unpack .../45-zlib1g-dev_1%3a1.3.dfsg+really1.3.1-1ubuntu1_arm64.deb ... 544s Unpacking zlib1g-dev:arm64 (1:1.3.dfsg+really1.3.1-1ubuntu1) ... 544s Selecting previously unselected package libpng-dev:arm64. 544s Preparing to unpack .../46-libpng-dev_1.6.47-1_arm64.deb ... 544s Unpacking libpng-dev:arm64 (1.6.47-1) ... 544s Selecting previously unselected package libreadline-dev:arm64. 544s Preparing to unpack .../47-libreadline-dev_8.2-6_arm64.deb ... 544s Unpacking libreadline-dev:arm64 (8.2-6) ... 544s Selecting previously unselected package liblzma-dev:arm64. 544s Preparing to unpack .../48-liblzma-dev_5.6.4-1_arm64.deb ... 544s Unpacking liblzma-dev:arm64 (5.6.4-1) ... 544s Selecting previously unselected package pkgconf-bin. 544s Preparing to unpack .../49-pkgconf-bin_1.8.1-4_arm64.deb ... 544s Unpacking pkgconf-bin (1.8.1-4) ... 544s Selecting previously unselected package pkgconf:arm64. 544s Preparing to unpack .../50-pkgconf_1.8.1-4_arm64.deb ... 544s Unpacking pkgconf:arm64 (1.8.1-4) ... 544s Selecting previously unselected package libtirpc-dev:arm64. 544s Preparing to unpack .../51-libtirpc-dev_1.3.4+ds-1.3_arm64.deb ... 544s Unpacking libtirpc-dev:arm64 (1.3.4+ds-1.3) ... 544s Selecting previously unselected package r-base-dev. 544s Preparing to unpack .../52-r-base-dev_4.4.3-1_all.deb ... 544s Unpacking r-base-dev (4.4.3-1) ... 544s Selecting previously unselected package pkg-r-autopkgtest. 544s Preparing to unpack .../53-pkg-r-autopkgtest_20231212ubuntu1_all.deb ... 544s Unpacking pkg-r-autopkgtest (20231212ubuntu1) ... 544s Setting up libjpeg-turbo8-dev:arm64 (2.1.5-3ubuntu2) ... 544s Setting up libncurses-dev:arm64 (6.5+20250216-2) ... 544s Setting up libreadline-dev:arm64 (8.2-6) ... 544s Setting up libpcre2-16-0:arm64 (10.45-1) ... 544s Setting up libpcre2-32-0:arm64 (10.45-1) ... 544s Setting up libtirpc-dev:arm64 (1.3.4+ds-1.3) ... 544s Setting up libpkgconf3:arm64 (1.8.1-4) ... 544s Setting up libmpc3:arm64 (1.3.1-1build2) ... 544s Setting up icu-devtools (76.1-1ubuntu2) ... 544s Setting up pkgconf-bin (1.8.1-4) ... 544s Setting up liblzma-dev:arm64 (5.6.4-1) ... 544s Setting up libubsan1:arm64 (15-20250222-0ubuntu1) ... 544s Setting up zlib1g-dev:arm64 (1:1.3.dfsg+really1.3.1-1ubuntu1) ... 544s Setting up libpcre2-posix3:arm64 (10.45-1) ... 544s Setting up libhwasan0:arm64 (15-20250222-0ubuntu1) ... 544s Setting up libasan8:arm64 (15-20250222-0ubuntu1) ... 544s Setting up libtsan2:arm64 (15-20250222-0ubuntu1) ... 544s Setting up libjpeg8-dev:arm64 (8c-2ubuntu11) ... 544s Setting up libisl23:arm64 (0.27-1) ... 544s Setting up libdeflate-dev:arm64 (1.23-1) ... 544s Setting up libicu-dev:arm64 (76.1-1ubuntu2) ... 544s Setting up libcc1-0:arm64 (15-20250222-0ubuntu1) ... 544s Setting up liblsan0:arm64 (15-20250222-0ubuntu1) ... 544s Setting up libblas-dev:arm64 (3.12.1-2) ... 544s update-alternatives: using /usr/lib/aarch64-linux-gnu/blas/libblas.so to provide /usr/lib/aarch64-linux-gnu/libblas.so (libblas.so-aarch64-linux-gnu) in auto mode 544s Setting up dctrl-tools (2.24-3build3) ... 544s Setting up libitm1:arm64 (15-20250222-0ubuntu1) ... 544s Setting up libbz2-dev:arm64 (1.0.8-6) ... 544s Setting up libpcre2-dev:arm64 (10.45-1) ... 544s Setting up libpng-dev:arm64 (1.6.47-1) ... 544s Setting up libjpeg-dev:arm64 (8c-2ubuntu11) ... 544s Setting up pkgconf:arm64 (1.8.1-4) ... 544s Setting up liblapack-dev:arm64 (3.12.1-2) ... 544s update-alternatives: using /usr/lib/aarch64-linux-gnu/lapack/liblapack.so to provide /usr/lib/aarch64-linux-gnu/liblapack.so (liblapack.so-aarch64-linux-gnu) in auto mode 544s Setting up cpp-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 544s Setting up libgcc-14-dev:arm64 (14.2.0-17ubuntu3) ... 544s Setting up libstdc++-14-dev:arm64 (14.2.0-17ubuntu3) ... 544s Setting up libgfortran-14-dev:arm64 (14.2.0-17ubuntu3) ... 544s Setting up cpp-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 544s Setting up cpp-14 (14.2.0-17ubuntu3) ... 544s Setting up cpp (4:14.2.0-1ubuntu1) ... 544s Setting up gcc-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 544s Setting up gcc-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 544s Setting up g++-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 544s Setting up gcc-14 (14.2.0-17ubuntu3) ... 544s Setting up gfortran-14-aarch64-linux-gnu (14.2.0-17ubuntu3) ... 544s Setting up g++-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 544s Setting up gfortran-aarch64-linux-gnu (4:14.2.0-1ubuntu1) ... 544s Setting up g++-14 (14.2.0-17ubuntu3) ... 544s Setting up gfortran-14 (14.2.0-17ubuntu3) ... 544s Setting up gcc (4:14.2.0-1ubuntu1) ... 545s Setting up g++ (4:14.2.0-1ubuntu1) ... 545s update-alternatives: using /usr/bin/g++ to provide /usr/bin/c++ (c++) in auto mode 545s Setting up build-essential (12.10ubuntu1) ... 545s Setting up gfortran (4:14.2.0-1ubuntu1) ... 545s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f95 (f95) in auto mode 545s update-alternatives: warning: skip creation of /usr/share/man/man1/f95.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f95) doesn't exist 545s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f77 (f77) in auto mode 545s update-alternatives: warning: skip creation of /usr/share/man/man1/f77.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f77) doesn't exist 545s Setting up r-base-dev (4.4.3-1) ... 545s Setting up pkg-r-autopkgtest (20231212ubuntu1) ... 545s Processing triggers for libc-bin (2.41-1ubuntu2) ... 545s Processing triggers for man-db (2.13.0-1) ... 546s Processing triggers for install-info (7.1.1-1) ... 547s autopkgtest [15:32:54]: test pkg-r-autopkgtest: /usr/share/dh-r/pkg-r-autopkgtest 547s autopkgtest [15:32:54]: test pkg-r-autopkgtest: [----------------------- 547s Test: Try to load the R library DoseFinding 547s 547s R version 4.4.3 (2025-02-28) -- "Trophy Case" 547s Copyright (C) 2025 The R Foundation for Statistical Computing 547s Platform: aarch64-unknown-linux-gnu 547s 547s R is free software and comes with ABSOLUTELY NO WARRANTY. 547s You are welcome to redistribute it under certain conditions. 547s Type 'license()' or 'licence()' for distribution details. 547s 547s R is a collaborative project with many contributors. 547s Type 'contributors()' for more information and 547s 'citation()' on how to cite R or R packages in publications. 547s 547s Type 'demo()' for some demos, 'help()' for on-line help, or 547s 'help.start()' for an HTML browser interface to help. 547s Type 'q()' to quit R. 547s 548s > library('DoseFinding') 549s > 549s > 549s Other tests are currently unsupported! 549s They will be progressively added. 549s autopkgtest [15:32:56]: test pkg-r-autopkgtest: -----------------------] 550s autopkgtest [15:32:57]: test pkg-r-autopkgtest: - - - - - - - - - - results - - - - - - - - - - 550s pkg-r-autopkgtest PASS 550s autopkgtest [15:32:57]: @@@@@@@@@@@@@@@@@@@@ summary 550s run-unit-test PASS 550s pkg-r-autopkgtest PASS 568s nova [W] Using flock in prodstack6-arm64 568s flock: timeout while waiting to get lock 568s Creating nova instance adt-plucky-arm64-r-cran-dosefinding-20250315-152345-juju-7f2275-prod-proposed-migration-environment-15-ae110736-73de-477b-a603-4c58cee7a008 from image adt/ubuntu-plucky-arm64-server-20250315.img (UUID bd6e766c-b51f-4b53-86d6-23aa4d18f524)... 568s nova [W] Timed out waiting for f0766043-ad5e-4a5d-8b94-21ee425db46b to get deleted.