0s autopkgtest [22:06:06]: starting date and time: 2025-03-15 22:06:06+0000 0s autopkgtest [22:06:06]: git checkout: 325255d2 Merge branch 'pin-any-arch' into 'ubuntu/production' 0s autopkgtest [22:06:06]: host juju-7f2275-prod-proposed-migration-environment-2; command line: /home/ubuntu/autopkgtest/runner/autopkgtest --output-dir /tmp/autopkgtest-work.dpn6jo9i/out --timeout-copy=6000 --setup-commands /home/ubuntu/autopkgtest-cloud/worker-config-production/setup-canonical.sh --apt-pocket=proposed=src:glibc --apt-upgrade r-cran-dosefinding --timeout-short=300 --timeout-copy=20000 --timeout-build=20000 --env=ADT_TEST_TRIGGERS=glibc/2.41-1ubuntu2 -- ssh -s /home/ubuntu/autopkgtest/ssh-setup/nova -- --flavor autopkgtest --security-groups autopkgtest-juju-7f2275-prod-proposed-migration-environment-2@lcy02-71.secgroup --name adt-plucky-amd64-r-cran-dosefinding-20250315-220606-juju-7f2275-prod-proposed-migration-environment-2-3e42c4f3-bee0-4546-a5c4-d13129a7d601 --image adt/ubuntu-plucky-amd64-server --keyname testbed-juju-7f2275-prod-proposed-migration-environment-2 --net-id=net_prod-proposed-migration -e TERM=linux -e ''"'"'http_proxy=http://squid.internal:3128'"'"'' -e ''"'"'https_proxy=http://squid.internal:3128'"'"'' -e ''"'"'no_proxy=127.0.0.1,127.0.1.1,login.ubuntu.com,localhost,localdomain,novalocal,internal,archive.ubuntu.com,ports.ubuntu.com,security.ubuntu.com,ddebs.ubuntu.com,changelogs.ubuntu.com,keyserver.ubuntu.com,launchpadlibrarian.net,launchpadcontent.net,launchpad.net,10.24.0.0/24,keystone.ps5.canonical.com,objectstorage.prodstack5.canonical.com,radosgw.ps5.canonical.com'"'"'' --mirror=http://ftpmaster.internal/ubuntu/ 47s autopkgtest [22:06:53]: testbed dpkg architecture: amd64 47s autopkgtest [22:06:53]: testbed apt version: 2.9.31ubuntu1 47s autopkgtest [22:06:53]: @@@@@@@@@@@@@@@@@@@@ test bed setup 47s autopkgtest [22:06:53]: testbed release detected to be: None 48s autopkgtest [22:06:54]: updating testbed package index (apt update) 48s Get:1 http://ftpmaster.internal/ubuntu plucky-proposed InRelease [126 kB] 48s Hit:2 http://ftpmaster.internal/ubuntu plucky InRelease 48s Hit:3 http://ftpmaster.internal/ubuntu plucky-updates InRelease 48s Hit:4 http://ftpmaster.internal/ubuntu plucky-security InRelease 48s Get:5 http://ftpmaster.internal/ubuntu plucky-proposed/main Sources [44.1 kB] 48s Get:6 http://ftpmaster.internal/ubuntu plucky-proposed/universe Sources [369 kB] 48s Get:7 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse Sources [14.5 kB] 48s Get:8 http://ftpmaster.internal/ubuntu plucky-proposed/main i386 Packages [67.4 kB] 48s Get:9 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 Packages [85.7 kB] 48s Get:10 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 c-n-f Metadata [1852 B] 48s Get:11 http://ftpmaster.internal/ubuntu plucky-proposed/restricted amd64 c-n-f Metadata [116 B] 48s Get:12 http://ftpmaster.internal/ubuntu plucky-proposed/universe amd64 Packages [342 kB] 48s Get:13 http://ftpmaster.internal/ubuntu plucky-proposed/universe i386 Packages [174 kB] 48s Get:14 http://ftpmaster.internal/ubuntu plucky-proposed/universe amd64 c-n-f Metadata [15.3 kB] 48s Get:15 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse i386 Packages [8544 B] 48s Get:16 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse amd64 Packages [16.1 kB] 48s Get:17 http://ftpmaster.internal/ubuntu plucky-proposed/multiverse amd64 c-n-f Metadata [628 B] 48s Fetched 1265 kB in 0s (5090 kB/s) 49s Reading package lists... 49s Reading package lists... 50s Building dependency tree... 50s Reading state information... 50s Calculating upgrade... 50s Calculating upgrade... 51s The following package was automatically installed and is no longer required: 51s libnl-genl-3-200 51s Use 'sudo apt autoremove' to remove it. 51s The following NEW packages will be installed: 51s bpftool libdebuginfod-common libdebuginfod1t64 linux-headers-6.14.0-10 51s linux-headers-6.14.0-10-generic linux-image-6.14.0-10-generic 51s linux-modules-6.14.0-10-generic linux-modules-extra-6.14.0-10-generic 51s linux-perf linux-tools-6.14.0-10 linux-tools-6.14.0-10-generic pnp.ids 51s The following packages will be upgraded: 51s apparmor apt apt-utils binutils binutils-common binutils-x86-64-linux-gnu 51s cloud-init cloud-init-base curl dosfstools fwupd gir1.2-girepository-2.0 51s gir1.2-glib-2.0 htop hwdata libapparmor1 libapt-pkg7.0 libaudit-common 51s libaudit1 libbinutils libbrotli1 libcap-ng0 libctf-nobfd0 libctf0 51s libcurl3t64-gnutls libcurl4t64 libestr0 libfwupd3 libgirepository-1.0-1 51s libglib2.0-0t64 libglib2.0-data libgprofng0 libjemalloc2 liblz4-1 liblzma5 51s libmm-glib0 libncurses6 libncursesw6 libnl-3-200 libnl-genl-3-200 51s libnl-route-3-200 libpci3 libpython3-stdlib libpython3.13 51s libpython3.13-minimal libpython3.13-stdlib libselinux1 libsframe1 51s libsqlite3-0 libtinfo6 libxml2 linux-firmware linux-generic 51s linux-headers-generic linux-headers-virtual linux-image-generic 51s linux-image-virtual linux-libc-dev linux-tools-common linux-virtual 51s media-types ncurses-base ncurses-bin ncurses-term pci.ids pciutils 51s pinentry-curses python-apt-common python3 python3-apt python3-cffi-backend 51s python3-dbus python3-gi python3-jinja2 python3-lazr.uri python3-markupsafe 51s python3-minimal python3-systemd python3-yaml python3.13 python3.13-gdbm 51s python3.13-minimal rsync rsyslog strace xz-utils 51s 86 upgraded, 12 newly installed, 0 to remove and 0 not upgraded. 51s Need to get 807 MB of archives. 51s After this operation, 326 MB of additional disk space will be used. 51s Get:1 http://ftpmaster.internal/ubuntu plucky/main amd64 ncurses-bin amd64 6.5+20250216-2 [194 kB] 51s Get:2 http://ftpmaster.internal/ubuntu plucky/main amd64 ncurses-base all 6.5+20250216-2 [25.9 kB] 51s Get:3 http://ftpmaster.internal/ubuntu plucky/main amd64 ncurses-term all 6.5+20250216-2 [276 kB] 51s Get:4 http://ftpmaster.internal/ubuntu plucky/main amd64 liblz4-1 amd64 1.10.0-4 [66.4 kB] 51s Get:5 http://ftpmaster.internal/ubuntu plucky/main amd64 liblzma5 amd64 5.6.4-1 [157 kB] 51s Get:6 http://ftpmaster.internal/ubuntu plucky/main amd64 libapt-pkg7.0 amd64 2.9.33 [1138 kB] 51s Get:7 http://ftpmaster.internal/ubuntu plucky/main amd64 apt amd64 2.9.33 [1439 kB] 51s Get:8 http://ftpmaster.internal/ubuntu plucky/main amd64 apt-utils amd64 2.9.33 [222 kB] 51s Get:9 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-minimal amd64 3.13.2-2 [27.7 kB] 51s Get:10 http://ftpmaster.internal/ubuntu plucky/main amd64 python3 amd64 3.13.2-2 [24.0 kB] 51s Get:11 http://ftpmaster.internal/ubuntu plucky/main amd64 libpython3.13 amd64 3.13.2-2 [2341 kB] 51s Get:12 http://ftpmaster.internal/ubuntu plucky/main amd64 media-types all 13.0.0 [29.9 kB] 51s Get:13 http://ftpmaster.internal/ubuntu plucky/main amd64 libncurses6 amd64 6.5+20250216-2 [126 kB] 51s Get:14 http://ftpmaster.internal/ubuntu plucky/main amd64 libncursesw6 amd64 6.5+20250216-2 [165 kB] 51s Get:15 http://ftpmaster.internal/ubuntu plucky/main amd64 libtinfo6 amd64 6.5+20250216-2 [119 kB] 51s Get:16 http://ftpmaster.internal/ubuntu plucky/main amd64 libsqlite3-0 amd64 3.46.1-2 [715 kB] 51s Get:17 http://ftpmaster.internal/ubuntu plucky/main amd64 python3.13 amd64 3.13.2-2 [735 kB] 51s Get:18 http://ftpmaster.internal/ubuntu plucky/main amd64 python3.13-minimal amd64 3.13.2-2 [2365 kB] 51s Get:19 http://ftpmaster.internal/ubuntu plucky/main amd64 libpython3.13-minimal amd64 3.13.2-2 [883 kB] 51s Get:20 http://ftpmaster.internal/ubuntu plucky/main amd64 libpython3.13-stdlib amd64 3.13.2-2 [2066 kB] 51s Get:21 http://ftpmaster.internal/ubuntu plucky/main amd64 libpython3-stdlib amd64 3.13.2-2 [10.4 kB] 51s Get:22 http://ftpmaster.internal/ubuntu plucky/main amd64 rsync amd64 3.4.1+ds1-3 [482 kB] 51s Get:23 http://ftpmaster.internal/ubuntu plucky/main amd64 libdebuginfod-common all 0.192-4 [15.4 kB] 51s Get:24 http://ftpmaster.internal/ubuntu plucky/main amd64 libaudit-common all 1:4.0.2-2ubuntu2 [6628 B] 51s Get:25 http://ftpmaster.internal/ubuntu plucky/main amd64 libcap-ng0 amd64 0.8.5-4build1 [15.6 kB] 51s Get:26 http://ftpmaster.internal/ubuntu plucky/main amd64 libaudit1 amd64 1:4.0.2-2ubuntu2 [54.0 kB] 51s Get:27 http://ftpmaster.internal/ubuntu plucky/main amd64 libselinux1 amd64 3.7-3ubuntu3 [87.3 kB] 51s Get:28 http://ftpmaster.internal/ubuntu plucky/main amd64 gir1.2-girepository-2.0 amd64 1.83.4-1 [25.3 kB] 51s Get:29 http://ftpmaster.internal/ubuntu plucky/main amd64 gir1.2-glib-2.0 amd64 2.84.0-1 [184 kB] 52s Get:30 http://ftpmaster.internal/ubuntu plucky/main amd64 libglib2.0-0t64 amd64 2.84.0-1 [1669 kB] 52s Get:31 http://ftpmaster.internal/ubuntu plucky/main amd64 libgirepository-1.0-1 amd64 1.83.4-1 [89.5 kB] 52s Get:32 http://ftpmaster.internal/ubuntu plucky/main amd64 libapparmor1 amd64 4.1.0~beta5-0ubuntu8 [55.0 kB] 52s Get:33 http://ftpmaster.internal/ubuntu plucky/main amd64 libestr0 amd64 0.1.11-2 [8340 B] 52s Get:34 http://ftpmaster.internal/ubuntu plucky/main amd64 libglib2.0-data all 2.84.0-1 [53.0 kB] 52s Get:35 http://ftpmaster.internal/ubuntu plucky/main amd64 libxml2 amd64 2.12.7+dfsg+really2.9.14-0.2ubuntu5 [772 kB] 52s Get:36 http://ftpmaster.internal/ubuntu plucky/main amd64 python-apt-common all 2.9.9build1 [21.3 kB] 52s Get:37 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-apt amd64 2.9.9build1 [172 kB] 52s Get:38 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-cffi-backend amd64 1.17.1-2build2 [96.6 kB] 52s Get:39 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-dbus amd64 1.3.2-5build5 [102 kB] 52s Get:40 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-gi amd64 3.50.0-4build1 [252 kB] 52s Get:41 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-yaml amd64 6.0.2-1build2 [144 kB] 52s Get:42 http://ftpmaster.internal/ubuntu plucky/main amd64 rsyslog amd64 8.2412.0-2ubuntu2 [555 kB] 52s Get:43 http://ftpmaster.internal/ubuntu plucky/main amd64 apparmor amd64 4.1.0~beta5-0ubuntu8 [701 kB] 52s Get:44 http://ftpmaster.internal/ubuntu plucky/main amd64 dosfstools amd64 4.2-1.2 [95.0 kB] 52s Get:45 http://ftpmaster.internal/ubuntu plucky/main amd64 libnl-genl-3-200 amd64 3.7.0-1 [12.2 kB] 52s Get:46 http://ftpmaster.internal/ubuntu plucky/main amd64 libnl-route-3-200 amd64 3.7.0-1 [191 kB] 52s Get:47 http://ftpmaster.internal/ubuntu plucky/main amd64 libnl-3-200 amd64 3.7.0-1 [64.9 kB] 52s Get:48 http://ftpmaster.internal/ubuntu plucky/main amd64 pci.ids all 0.0~2025.03.09-1 [285 kB] 52s Get:49 http://ftpmaster.internal/ubuntu plucky/main amd64 pciutils amd64 1:3.13.0-2 [110 kB] 52s Get:50 http://ftpmaster.internal/ubuntu plucky/main amd64 libpci3 amd64 1:3.13.0-2 [39.8 kB] 52s Get:51 http://ftpmaster.internal/ubuntu plucky/main amd64 strace amd64 6.13+ds-1ubuntu1 [622 kB] 52s Get:52 http://ftpmaster.internal/ubuntu plucky/main amd64 xz-utils amd64 5.6.4-1 [278 kB] 52s Get:53 http://ftpmaster.internal/ubuntu plucky/main amd64 libgprofng0 amd64 2.44-3ubuntu1 [886 kB] 52s Get:54 http://ftpmaster.internal/ubuntu plucky/main amd64 libctf0 amd64 2.44-3ubuntu1 [96.5 kB] 52s Get:55 http://ftpmaster.internal/ubuntu plucky/main amd64 libctf-nobfd0 amd64 2.44-3ubuntu1 [98.9 kB] 52s Get:56 http://ftpmaster.internal/ubuntu plucky/main amd64 binutils-x86-64-linux-gnu amd64 2.44-3ubuntu1 [1108 kB] 52s Get:57 http://ftpmaster.internal/ubuntu plucky/main amd64 libbinutils amd64 2.44-3ubuntu1 [585 kB] 52s Get:58 http://ftpmaster.internal/ubuntu plucky/main amd64 binutils amd64 2.44-3ubuntu1 [208 kB] 52s Get:59 http://ftpmaster.internal/ubuntu plucky/main amd64 binutils-common amd64 2.44-3ubuntu1 [215 kB] 52s Get:60 http://ftpmaster.internal/ubuntu plucky/main amd64 libsframe1 amd64 2.44-3ubuntu1 [14.8 kB] 52s Get:61 http://ftpmaster.internal/ubuntu plucky/main amd64 hwdata all 0.393-3 [1562 B] 52s Get:62 http://ftpmaster.internal/ubuntu plucky/main amd64 pnp.ids all 0.393-3 [29.5 kB] 52s Get:63 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-tools-common all 6.14.0-10.10 [295 kB] 52s Get:64 http://ftpmaster.internal/ubuntu plucky/main amd64 bpftool amd64 7.6.0+6.14.0-10.10 [1147 kB] 52s Get:65 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-markupsafe amd64 2.1.5-1build4 [13.4 kB] 52s Get:66 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-jinja2 all 3.1.5-2ubuntu1 [109 kB] 52s Get:67 http://ftpmaster.internal/ubuntu plucky/main amd64 cloud-init-base all 25.1-0ubuntu3 [616 kB] 52s Get:68 http://ftpmaster.internal/ubuntu plucky/main amd64 libbrotli1 amd64 1.1.0-2build4 [365 kB] 52s Get:69 http://ftpmaster.internal/ubuntu plucky/main amd64 curl amd64 8.12.1-3ubuntu1 [258 kB] 52s Get:70 http://ftpmaster.internal/ubuntu plucky/main amd64 libcurl4t64 amd64 8.12.1-3ubuntu1 [437 kB] 52s Get:71 http://ftpmaster.internal/ubuntu plucky/main amd64 libcurl3t64-gnutls amd64 8.12.1-3ubuntu1 [432 kB] 52s Get:72 http://ftpmaster.internal/ubuntu plucky/main amd64 fwupd amd64 2.0.6-4 [5408 kB] 52s Get:73 http://ftpmaster.internal/ubuntu plucky/main amd64 libfwupd3 amd64 2.0.6-4 [136 kB] 52s Get:74 http://ftpmaster.internal/ubuntu plucky/main amd64 libmm-glib0 amd64 1.23.4-0ubuntu3 [251 kB] 52s Get:75 http://ftpmaster.internal/ubuntu plucky/main amd64 htop amd64 3.4.0-2 [195 kB] 52s Get:76 http://ftpmaster.internal/ubuntu plucky/main amd64 libdebuginfod1t64 amd64 0.192-4 [21.0 kB] 52s Get:77 http://ftpmaster.internal/ubuntu plucky/main amd64 libjemalloc2 amd64 5.3.0-3 [277 kB] 52s Get:78 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-firmware amd64 20250310.git9e1370d3-0ubuntu1 [571 MB] 61s Get:79 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-modules-6.14.0-10-generic amd64 6.14.0-10.10 [41.2 MB] 61s Get:80 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-image-6.14.0-10-generic amd64 6.14.0-10.10 [15.3 MB] 62s Get:81 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-modules-extra-6.14.0-10-generic amd64 6.14.0-10.10 [120 MB] 63s Get:82 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-generic amd64 6.14.0-10.10 [1730 B] 63s Get:83 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-image-generic amd64 6.14.0-10.10 [11.1 kB] 63s Get:84 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-virtual amd64 6.14.0-10.10 [1722 B] 63s Get:85 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-image-virtual amd64 6.14.0-10.10 [11.1 kB] 63s Get:86 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-headers-virtual amd64 6.14.0-10.10 [1642 B] 63s Get:87 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-headers-6.14.0-10 all 6.14.0-10.10 [14.2 MB] 63s Get:88 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-headers-6.14.0-10-generic amd64 6.14.0-10.10 [3915 kB] 63s Get:89 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-headers-generic amd64 6.14.0-10.10 [11.0 kB] 63s Get:90 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-libc-dev amd64 6.14.0-10.10 [1723 kB] 63s Get:91 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-perf amd64 6.14.0-10.10 [4122 kB] 63s Get:92 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-tools-6.14.0-10 amd64 6.14.0-10.10 [1394 kB] 63s Get:93 http://ftpmaster.internal/ubuntu plucky/main amd64 linux-tools-6.14.0-10-generic amd64 6.14.0-10.10 [830 B] 63s Get:94 http://ftpmaster.internal/ubuntu plucky/main amd64 pinentry-curses amd64 1.3.1-2ubuntu3 [42.3 kB] 63s Get:95 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-lazr.uri all 1.0.6-6 [13.7 kB] 63s Get:96 http://ftpmaster.internal/ubuntu plucky/main amd64 python3-systemd amd64 235-1build6 [43.9 kB] 63s Get:97 http://ftpmaster.internal/ubuntu plucky/main amd64 python3.13-gdbm amd64 3.13.2-2 [31.9 kB] 63s Get:98 http://ftpmaster.internal/ubuntu plucky/main amd64 cloud-init all 25.1-0ubuntu3 [2100 B] 63s Preconfiguring packages ... 63s Fetched 807 MB in 12s (66.6 MB/s) 64s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 64s Preparing to unpack .../ncurses-bin_6.5+20250216-2_amd64.deb ... 64s Unpacking ncurses-bin (6.5+20250216-2) over (6.5+20250216-1) ... 64s Setting up ncurses-bin (6.5+20250216-2) ... 64s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 64s Preparing to unpack .../ncurses-base_6.5+20250216-2_all.deb ... 64s Unpacking ncurses-base (6.5+20250216-2) over (6.5+20250216-1) ... 64s Setting up ncurses-base (6.5+20250216-2) ... 64s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 64s Preparing to unpack .../ncurses-term_6.5+20250216-2_all.deb ... 64s Unpacking ncurses-term (6.5+20250216-2) over (6.5+20250216-1) ... 64s Preparing to unpack .../liblz4-1_1.10.0-4_amd64.deb ... 64s Unpacking liblz4-1:amd64 (1.10.0-4) over (1.10.0-3) ... 64s Setting up liblz4-1:amd64 (1.10.0-4) ... 64s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 64s Preparing to unpack .../liblzma5_5.6.4-1_amd64.deb ... 64s Unpacking liblzma5:amd64 (5.6.4-1) over (5.6.3-1) ... 64s Setting up liblzma5:amd64 (5.6.4-1) ... 65s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 65s Preparing to unpack .../libapt-pkg7.0_2.9.33_amd64.deb ... 65s Unpacking libapt-pkg7.0:amd64 (2.9.33) over (2.9.31ubuntu1) ... 65s Setting up libapt-pkg7.0:amd64 (2.9.33) ... 65s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 65s Preparing to unpack .../archives/apt_2.9.33_amd64.deb ... 65s Unpacking apt (2.9.33) over (2.9.31ubuntu1) ... 65s Setting up apt (2.9.33) ... 66s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 109138 files and directories currently installed.) 66s Preparing to unpack .../apt-utils_2.9.33_amd64.deb ... 66s Unpacking apt-utils (2.9.33) over (2.9.31ubuntu1) ... 66s Preparing to unpack .../python3-minimal_3.13.2-2_amd64.deb ... 66s Unpacking python3-minimal (3.13.2-2) over (3.13.2-1) ... 66s Setting up python3-minimal (3.13.2-2) ... 66s (Reading database ... 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Preparing to unpack .../68-python3-systemd_235-1build6_amd64.deb ... 82s Unpacking python3-systemd (235-1build6) over (235-1build5) ... 82s Preparing to unpack .../69-python3.13-gdbm_3.13.2-2_amd64.deb ... 82s Unpacking python3.13-gdbm (3.13.2-2) over (3.13.2-1) ... 82s Preparing to unpack .../70-cloud-init_25.1-0ubuntu3_all.deb ... 82s Unpacking cloud-init (25.1-0ubuntu3) over (25.1-0ubuntu2) ... 82s Setting up linux-headers-6.14.0-10 (6.14.0-10.10) ... 82s Setting up media-types (13.0.0) ... 82s Installing new version of config file /etc/mime.types ... 82s Setting up linux-headers-6.14.0-10-generic (6.14.0-10.10) ... 82s Setting up libapparmor1:amd64 (4.1.0~beta5-0ubuntu8) ... 82s Setting up pci.ids (0.0~2025.03.09-1) ... 82s Setting up apt-utils (2.9.33) ... 82s Setting up libdebuginfod-common (0.192-4) ... 82s Setting up linux-firmware (20250310.git9e1370d3-0ubuntu1) ... 82s Setting up bpftool (7.6.0+6.14.0-10.10) ... 82s Setting up libestr0:amd64 (0.1.11-2) ... 82s Setting up libbrotli1:amd64 (1.1.0-2build4) ... 82s Setting up libsqlite3-0:amd64 (3.46.1-2) ... 82s Setting up dosfstools (4.2-1.2) ... 82s Setting up rsyslog (8.2412.0-2ubuntu2) ... 82s info: The user `syslog' is already a member of `adm'. 83s Setting up binutils-common:amd64 (2.44-3ubuntu1) ... 83s Setting up libcurl3t64-gnutls:amd64 (8.12.1-3ubuntu1) ... 83s Setting up linux-libc-dev:amd64 (6.14.0-10.10) ... 83s Setting up libctf-nobfd0:amd64 (2.44-3ubuntu1) ... 83s Setting up linux-headers-generic (6.14.0-10.10) ... 83s Setting up libjemalloc2:amd64 (5.3.0-3) ... 83s Setting up libsframe1:amd64 (2.44-3ubuntu1) ... 83s Setting up libpython3.13-minimal:amd64 (3.13.2-2) ... 83s Setting up apparmor (4.1.0~beta5-0ubuntu8) ... 83s Installing new version of config file /etc/apparmor.d/openvpn ... 84s Reloading AppArmor profiles 86s Setting up libglib2.0-0t64:amd64 (2.84.0-1) ... 86s No schema files found: doing nothing. 86s Setting up libglib2.0-data (2.84.0-1) ... 86s Setting up libncurses6:amd64 (6.5+20250216-2) ... 86s Setting up strace (6.13+ds-1ubuntu1) ... 86s Setting up xz-utils (5.6.4-1) ... 86s Setting up gir1.2-glib-2.0:amd64 (2.84.0-1) ... 86s Setting up linux-modules-6.14.0-10-generic (6.14.0-10.10) ... 88s Setting up libncursesw6:amd64 (6.5+20250216-2) ... 88s Setting up libpci3:amd64 (1:3.13.0-2) ... 88s Setting up python-apt-common (2.9.9build1) ... 88s Setting up libmm-glib0:amd64 (1.23.4-0ubuntu3) ... 88s Setting up pnp.ids (0.393-3) ... 88s Setting up libnl-3-200:amd64 (3.7.0-1) ... 88s Setting up python3.13-minimal (3.13.2-2) ... 89s Setting up libgirepository-1.0-1:amd64 (1.83.4-1) ... 89s Setting up libbinutils:amd64 (2.44-3ubuntu1) ... 89s Setting up libpython3.13-stdlib:amd64 (3.13.2-2) ... 89s Setting up libxml2:amd64 (2.12.7+dfsg+really2.9.14-0.2ubuntu5) ... 89s Setting up rsync (3.4.1+ds1-3) ... 90s rsync.service is a disabled or a static unit not running, not starting it. 90s Setting up python3.13-gdbm (3.13.2-2) ... 90s Setting up libpython3-stdlib:amd64 (3.13.2-2) ... 90s Setting up ncurses-term (6.5+20250216-2) ... 90s Setting up libctf0:amd64 (2.44-3ubuntu1) ... 90s Setting up libpython3.13:amd64 (3.13.2-2) ... 90s Setting up pinentry-curses (1.3.1-2ubuntu3) ... 90s Setting up libdebuginfod1t64:amd64 (0.192-4) ... 90s Setting up linux-headers-virtual (6.14.0-10.10) ... 90s Setting up libcurl4t64:amd64 (8.12.1-3ubuntu1) ... 90s Setting up python3.13 (3.13.2-2) ... 90s Setting up htop (3.4.0-2) ... 90s Setting up linux-image-6.14.0-10-generic (6.14.0-10.10) ... 93s I: /boot/vmlinuz.old is now a symlink to vmlinuz-6.12.0-16-generic 93s I: /boot/initrd.img.old is now a symlink to initrd.img-6.12.0-16-generic 93s I: /boot/vmlinuz is now a symlink to vmlinuz-6.14.0-10-generic 93s I: /boot/initrd.img is now a symlink to initrd.img-6.14.0-10-generic 93s Setting up libfwupd3:amd64 (2.0.6-4) ... 93s Setting up python3 (3.13.2-2) ... 93s Setting up python3-markupsafe (2.1.5-1build4) ... 93s Setting up linux-modules-extra-6.14.0-10-generic (6.14.0-10.10) ... 95s Setting up libnl-route-3-200:amd64 (3.7.0-1) ... 95s Setting up hwdata (0.393-3) ... 95s Setting up python3-jinja2 (3.1.5-2ubuntu1) ... 95s Setting up libgprofng0:amd64 (2.44-3ubuntu1) ... 95s Setting up linux-perf (6.14.0-10.10) ... 95s Setting up gir1.2-girepository-2.0:amd64 (1.83.4-1) ... 95s Setting up python3-gi (3.50.0-4build1) ... 96s Setting up pciutils (1:3.13.0-2) ... 96s Setting up libnl-genl-3-200:amd64 (3.7.0-1) ... 96s Setting up curl (8.12.1-3ubuntu1) ... 96s Setting up linux-image-virtual (6.14.0-10.10) ... 96s Setting up linux-tools-common (6.14.0-10.10) ... 96s Setting up fwupd (2.0.6-4) ... 96s fwupd-refresh.service is a disabled or a static unit not running, not starting it. 96s fwupd.service is a disabled or a static unit not running, not starting it. 96s Setting up python3-systemd (235-1build6) ... 96s Setting up python3-cffi-backend:amd64 (1.17.1-2build2) ... 96s Setting up binutils-x86-64-linux-gnu (2.44-3ubuntu1) ... 96s Setting up linux-image-generic (6.14.0-10.10) ... 96s Setting up python3-dbus (1.3.2-5build5) ... 96s Setting up linux-tools-6.14.0-10 (6.14.0-10.10) ... 96s Setting up linux-generic (6.14.0-10.10) ... 96s Setting up python3-apt (2.9.9build1) ... 97s Setting up python3-yaml (6.0.2-1build2) ... 97s Setting up python3-lazr.uri (1.0.6-6) ... 97s Setting up binutils (2.44-3ubuntu1) ... 97s Setting up cloud-init-base (25.1-0ubuntu3) ... 98s Setting up linux-virtual (6.14.0-10.10) ... 98s Setting up linux-tools-6.14.0-10-generic (6.14.0-10.10) ... 98s Setting up cloud-init (25.1-0ubuntu3) ... 98s Processing triggers for systemd (257.3-1ubuntu3) ... 99s Processing triggers for man-db (2.13.0-1) ... 100s Processing triggers for dbus (1.16.2-1ubuntu1) ... 100s Processing triggers for libc-bin (2.41-1ubuntu1) ... 100s Processing triggers for initramfs-tools (0.146ubuntu1) ... 100s update-initramfs: Generating /boot/initrd.img-6.12.0-16-generic 100s W: No lz4 in /usr/bin:/sbin:/bin, using gzip 111s Processing triggers for linux-image-6.14.0-10-generic (6.14.0-10.10) ... 111s /etc/kernel/postinst.d/initramfs-tools: 111s update-initramfs: Generating /boot/initrd.img-6.14.0-10-generic 111s W: No lz4 in /usr/bin:/sbin:/bin, using gzip 121s /etc/kernel/postinst.d/zz-update-grub: 121s Sourcing file `/etc/default/grub' 121s Sourcing file `/etc/default/grub.d/50-cloudimg-settings.cfg' 121s Sourcing file `/etc/default/grub.d/90-autopkgtest.cfg' 121s Generating grub configuration file ... 121s Found linux image: /boot/vmlinuz-6.14.0-10-generic 121s Found initrd image: /boot/initrd.img-6.14.0-10-generic 121s Found linux image: /boot/vmlinuz-6.12.0-16-generic 121s Found initrd image: /boot/initrd.img-6.12.0-16-generic 121s Found linux image: /boot/vmlinuz-6.11.0-8-generic 121s Found initrd image: /boot/initrd.img-6.11.0-8-generic 121s Warning: os-prober will not be executed to detect other bootable partitions. 121s Systems on them will not be added to the GRUB boot configuration. 121s Check GRUB_DISABLE_OS_PROBER documentation entry. 121s Adding boot menu entry for UEFI Firmware Settings ... 121s done 123s Reading package lists... 123s Building dependency tree... 123s Reading state information... 123s Solving dependencies... 123s The following packages will be REMOVED: 123s libnl-genl-3-200* libnsl2* libpython3.12-minimal* libpython3.12-stdlib* 123s libpython3.12t64* linux-headers-6.11.0-8* linux-headers-6.11.0-8-generic* 123s linux-headers-6.12.0-16* linux-headers-6.12.0-16-generic* 123s linux-image-6.11.0-8-generic* linux-image-6.12.0-16-generic* 123s linux-modules-6.11.0-8-generic* linux-modules-6.12.0-16-generic* 123s linux-modules-extra-6.12.0-16-generic* linux-tools-6.11.0-8* 123s linux-tools-6.11.0-8-generic* linux-tools-6.12.0-16* 123s linux-tools-6.12.0-16-generic* 124s 0 upgraded, 0 newly installed, 18 to remove and 5 not upgraded. 124s After this operation, 545 MB disk space will be freed. 124s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 148643 files and directories currently installed.) 124s Removing libnl-genl-3-200:amd64 (3.7.0-1) ... 124s Removing linux-tools-6.11.0-8-generic (6.11.0-8.8) ... 124s Removing linux-tools-6.11.0-8 (6.11.0-8.8) ... 124s Removing libpython3.12t64:amd64 (3.12.9-1) ... 124s Removing libpython3.12-stdlib:amd64 (3.12.9-1) ... 124s Removing libnsl2:amd64 (1.3.0-3build3) ... 124s Removing libpython3.12-minimal:amd64 (3.12.9-1) ... 124s Removing linux-headers-6.11.0-8-generic (6.11.0-8.8) ... 125s Removing linux-headers-6.11.0-8 (6.11.0-8.8) ... 127s Removing linux-headers-6.12.0-16-generic (6.12.0-16.16) ... 127s Removing linux-headers-6.12.0-16 (6.12.0-16.16) ... 129s Removing linux-image-6.11.0-8-generic (6.11.0-8.8) ... 129s /etc/kernel/postrm.d/initramfs-tools: 129s update-initramfs: Deleting /boot/initrd.img-6.11.0-8-generic 129s /etc/kernel/postrm.d/zz-update-grub: 129s Sourcing file `/etc/default/grub' 129s Sourcing file `/etc/default/grub.d/50-cloudimg-settings.cfg' 129s Sourcing file `/etc/default/grub.d/90-autopkgtest.cfg' 129s Generating grub configuration file ... 130s Found linux image: /boot/vmlinuz-6.14.0-10-generic 130s Found initrd image: /boot/initrd.img-6.14.0-10-generic 130s Found linux image: /boot/vmlinuz-6.12.0-16-generic 130s Found initrd image: /boot/initrd.img-6.12.0-16-generic 130s Warning: os-prober will not be executed to detect other bootable partitions. 130s Systems on them will not be added to the GRUB boot configuration. 130s Check GRUB_DISABLE_OS_PROBER documentation entry. 130s Adding boot menu entry for UEFI Firmware Settings ... 130s done 130s Removing linux-image-6.12.0-16-generic (6.12.0-16.16) ... 130s W: Removing the running kernel 130s I: /boot/vmlinuz.old is now a symlink to vmlinuz-6.14.0-10-generic 130s I: /boot/initrd.img.old is now a symlink to initrd.img-6.14.0-10-generic 130s /etc/kernel/postrm.d/initramfs-tools: 130s update-initramfs: Deleting /boot/initrd.img-6.12.0-16-generic 130s /etc/kernel/postrm.d/zz-update-grub: 130s Sourcing file `/etc/default/grub' 130s Sourcing file `/etc/default/grub.d/50-cloudimg-settings.cfg' 130s Sourcing file `/etc/default/grub.d/90-autopkgtest.cfg' 130s Generating grub configuration file ... 131s Found linux image: /boot/vmlinuz-6.14.0-10-generic 131s Found initrd image: /boot/initrd.img-6.14.0-10-generic 131s Warning: os-prober will not be executed to detect other bootable partitions. 131s Systems on them will not be added to the GRUB boot configuration. 131s Check GRUB_DISABLE_OS_PROBER documentation entry. 131s Adding boot menu entry for UEFI Firmware Settings ... 131s done 131s Removing linux-modules-6.11.0-8-generic (6.11.0-8.8) ... 131s Removing linux-modules-extra-6.12.0-16-generic (6.12.0-16.16) ... 133s Removing linux-modules-6.12.0-16-generic (6.12.0-16.16) ... 133s Removing linux-tools-6.12.0-16-generic (6.12.0-16.16) ... 133s Removing linux-tools-6.12.0-16 (6.12.0-16.16) ... 133s Processing triggers for libc-bin (2.41-1ubuntu1) ... 133s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 76972 files and directories currently installed.) 133s Purging configuration files for linux-image-6.11.0-8-generic (6.11.0-8.8) ... 133s Purging configuration files for libpython3.12-minimal:amd64 (3.12.9-1) ... 133s Purging configuration files for linux-modules-extra-6.12.0-16-generic (6.12.0-16.16) ... 133s Purging configuration files for linux-modules-6.12.0-16-generic (6.12.0-16.16) ... 133s dpkg: warning: while removing linux-modules-6.12.0-16-generic, directory '/lib/modules/6.12.0-16-generic' not empty so not removed 133s Purging configuration files for linux-modules-6.11.0-8-generic (6.11.0-8.8) ... 133s Purging configuration files for linux-image-6.12.0-16-generic (6.12.0-16.16) ... 133s rmdir: failed to remove '/lib/modules/6.12.0-16-generic': Directory not empty 133s autopkgtest [22:08:19]: upgrading testbed (apt dist-upgrade and autopurge) 133s Reading package lists... 134s Building dependency tree... 134s Reading state information... 134s Calculating upgrade...Starting pkgProblemResolver with broken count: 0 134s Starting 2 pkgProblemResolver with broken count: 0 134s Done 135s Entering ResolveByKeep 135s 135s Calculating upgrade... 135s The following packages will be upgraded: 135s libc-bin libc-dev-bin libc6 libc6-dev locales 135s 5 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 135s Need to get 10.5 MB of archives. 135s After this operation, 1024 B of additional disk space will be used. 135s Get:1 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 libc6-dev amd64 2.41-1ubuntu2 [2183 kB] 135s Get:2 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 libc-dev-bin amd64 2.41-1ubuntu2 [24.7 kB] 135s Get:3 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 libc6 amd64 2.41-1ubuntu2 [3327 kB] 135s Get:4 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 libc-bin amd64 2.41-1ubuntu2 [700 kB] 135s Get:5 http://ftpmaster.internal/ubuntu plucky-proposed/main amd64 locales all 2.41-1ubuntu2 [4246 kB] 136s Preconfiguring packages ... 136s Fetched 10.5 MB in 0s (36.4 MB/s) 136s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 76968 files and directories currently installed.) 136s Preparing to unpack .../libc6-dev_2.41-1ubuntu2_amd64.deb ... 136s Unpacking libc6-dev:amd64 (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 136s Preparing to unpack .../libc-dev-bin_2.41-1ubuntu2_amd64.deb ... 136s Unpacking libc-dev-bin (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 136s Preparing to unpack .../libc6_2.41-1ubuntu2_amd64.deb ... 136s Unpacking libc6:amd64 (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 136s Setting up libc6:amd64 (2.41-1ubuntu2) ... 137s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 76968 files and directories currently installed.) 137s Preparing to unpack .../libc-bin_2.41-1ubuntu2_amd64.deb ... 137s Unpacking libc-bin (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 137s Setting up libc-bin (2.41-1ubuntu2) ... 137s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 76968 files and directories currently installed.) 137s Preparing to unpack .../locales_2.41-1ubuntu2_all.deb ... 137s Unpacking locales (2.41-1ubuntu2) over (2.41-1ubuntu1) ... 137s Setting up locales (2.41-1ubuntu2) ... 138s Generating locales (this might take a while)... 139s en_US.UTF-8... done 139s Generation complete. 139s Setting up libc-dev-bin (2.41-1ubuntu2) ... 139s Setting up libc6-dev:amd64 (2.41-1ubuntu2) ... 139s Processing triggers for man-db (2.13.0-1) ... 140s Processing triggers for systemd (257.3-1ubuntu3) ... 141s Reading package lists... 141s Building dependency tree... 141s Reading state information... 142s Starting pkgProblemResolver with broken count: 0 142s Starting 2 pkgProblemResolver with broken count: 0 142s Done 142s Solving dependencies... 142s 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. 142s autopkgtest [22:08:28]: rebooting testbed after setup commands that affected boot 163s autopkgtest [22:08:49]: testbed running kernel: Linux 6.14.0-10-generic #10-Ubuntu SMP PREEMPT_DYNAMIC Wed Mar 12 16:07:00 UTC 2025 164s autopkgtest [22:08:50]: @@@@@@@@@@@@@@@@@@@@ apt-source r-cran-dosefinding 165s Get:1 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (dsc) [2322 B] 165s Get:2 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (tar) [698 kB] 165s Get:3 http://ftpmaster.internal/ubuntu plucky/universe r-cran-dosefinding 1.3-1-1 (diff) [4244 B] 165s gpgv: Signature made Fri Mar 14 00:07:33 2025 UTC 165s gpgv: using RSA key 73471499CC60ED9EEE805946C5BD6C8F2295D502 165s gpgv: issuer "plessy@debian.org" 165s gpgv: Can't check signature: No public key 165s dpkg-source: warning: cannot verify inline signature for ./r-cran-dosefinding_1.3-1-1.dsc: no acceptable signature found 165s autopkgtest [22:08:51]: testing package r-cran-dosefinding version 1.3-1-1 166s autopkgtest [22:08:52]: build not needed 168s autopkgtest [22:08:54]: test run-unit-test: preparing testbed 169s Reading package lists... 169s Building dependency tree... 169s Reading state information... 169s Starting pkgProblemResolver with broken count: 0 169s Starting 2 pkgProblemResolver with broken count: 0 169s Done 170s The following NEW packages will be installed: 170s fontconfig fontconfig-config fonts-dejavu-core fonts-dejavu-mono 170s fonts-font-awesome fonts-glyphicons-halflings fonts-mathjax 170s javascript-common libblas3 libcairo2 libdatrie1 libdeflate0 libfontconfig1 170s libgfortran5 libgomp1 libgraphite2-3 libharfbuzz0b libice6 libjbig0 170s libjpeg-turbo8 libjpeg8 libjs-bootstrap libjs-bootstrap4 libjs-d3 170s libjs-es5-shim libjs-highlight.js libjs-jquery libjs-jquery-datatables 170s libjs-jquery-selectize.js libjs-jquery-ui libjs-json libjs-mathjax 170s libjs-microplugin.js libjs-modernizr libjs-popper.js libjs-prettify 170s libjs-sifter.js libjs-twitter-bootstrap-datepicker liblapack3 liblerc4 170s liblua5.4-0 libpango-1.0-0 libpangocairo-1.0-0 libpangoft2-1.0-0 170s libpaper-utils libpaper2 libpixman-1-0 libsharpyuv0 libsm6 libtcl8.6 170s libthai-data libthai0 libtiff6 libtk8.6 libwebp7 libxcb-render0 libxcb-shm0 170s libxft2 libxrender1 libxss1 libxt6t64 littler node-bootstrap-sass 170s node-html5shiv node-normalize.css pandoc pandoc-data r-base-core 170s r-cran-base64enc r-cran-brio r-cran-bslib r-cran-cachem r-cran-callr 170s r-cran-cli r-cran-codetools r-cran-colorspace r-cran-commonmark 170s r-cran-crayon r-cran-desc r-cran-diffobj r-cran-digest r-cran-dosefinding 170s r-cran-evaluate r-cran-fansi r-cran-farver r-cran-fastmap r-cran-fontawesome 170s r-cran-fs r-cran-ggplot2 r-cran-glue r-cran-gtable r-cran-highr 170s r-cran-htmltools r-cran-httpuv r-cran-isoband r-cran-jquerylib 170s r-cran-jsonlite r-cran-knitr r-cran-labeling r-cran-later r-cran-lattice 170s r-cran-lifecycle r-cran-littler r-cran-magrittr r-cran-mass r-cran-matrix 170s r-cran-memoise r-cran-mgcv r-cran-mime r-cran-multcomp r-cran-munsell 170s r-cran-mvtnorm r-cran-nlme r-cran-numderiv r-cran-pillar r-cran-pkgbuild 170s r-cran-pkgconfig r-cran-pkgkitten r-cran-pkgload r-cran-praise 170s r-cran-processx r-cran-promises r-cran-ps r-cran-quadprog r-cran-r6 170s r-cran-rappdirs r-cran-rcolorbrewer r-cran-rcpp r-cran-rlang 170s r-cran-rmarkdown r-cran-rprojroot r-cran-rsolnp r-cran-sandwich r-cran-sass 170s r-cran-scales r-cran-shiny r-cran-sourcetools r-cran-survival 170s r-cran-testthat r-cran-th.data r-cran-tibble r-cran-tinytex r-cran-truncnorm 170s r-cran-utf8 r-cran-vctrs r-cran-viridislite r-cran-waldo r-cran-withr 170s r-cran-xfun r-cran-xtable r-cran-yaml r-cran-zoo unzip x11-common xdg-utils 170s zip 170s 0 upgraded, 156 newly installed, 0 to remove and 0 not upgraded. 170s Need to get 156 MB of archives. 170s After this operation, 481 MB of additional disk space will be used. 170s Get:1 http://ftpmaster.internal/ubuntu plucky/main amd64 fonts-dejavu-mono all 2.37-8 [502 kB] 170s Get:2 http://ftpmaster.internal/ubuntu plucky/main amd64 fonts-dejavu-core all 2.37-8 [835 kB] 170s Get:3 http://ftpmaster.internal/ubuntu plucky/main amd64 fontconfig-config amd64 2.15.0-2ubuntu1 [37.4 kB] 170s Get:4 http://ftpmaster.internal/ubuntu plucky/main amd64 libfontconfig1 amd64 2.15.0-2ubuntu1 [164 kB] 170s Get:5 http://ftpmaster.internal/ubuntu plucky/main amd64 fontconfig amd64 2.15.0-2ubuntu1 [180 kB] 170s Get:6 http://ftpmaster.internal/ubuntu plucky/main amd64 fonts-font-awesome all 5.0.10+really4.7.0~dfsg-4.1 [516 kB] 170s Get:7 http://ftpmaster.internal/ubuntu plucky/universe amd64 fonts-glyphicons-halflings all 1.009~3.4.1+dfsg-3 [118 kB] 170s Get:8 http://ftpmaster.internal/ubuntu plucky/main amd64 fonts-mathjax all 2.7.9+dfsg-1 [2208 kB] 170s Get:9 http://ftpmaster.internal/ubuntu plucky/main amd64 javascript-common all 12 [5216 B] 170s Get:10 http://ftpmaster.internal/ubuntu plucky/main amd64 libblas3 amd64 3.12.1-2 [359 kB] 170s Get:11 http://ftpmaster.internal/ubuntu plucky/main amd64 libpixman-1-0 amd64 0.44.0-3 [427 kB] 170s Get:12 http://ftpmaster.internal/ubuntu plucky/main amd64 libxcb-render0 amd64 1.17.0-2 [16.2 kB] 170s Get:13 http://ftpmaster.internal/ubuntu plucky/main amd64 libxcb-shm0 amd64 1.17.0-2 [5758 B] 170s Get:14 http://ftpmaster.internal/ubuntu plucky/main amd64 libxrender1 amd64 1:0.9.10-1.1build1 [19.0 kB] 170s Get:15 http://ftpmaster.internal/ubuntu plucky/main amd64 libcairo2 amd64 1.18.2-2 [569 kB] 170s Get:16 http://ftpmaster.internal/ubuntu plucky/main amd64 libdatrie1 amd64 0.2.13-3build1 [19.0 kB] 170s Get:17 http://ftpmaster.internal/ubuntu plucky/main amd64 libdeflate0 amd64 1.23-1 [64.1 kB] 170s Get:18 http://ftpmaster.internal/ubuntu plucky/main amd64 libgfortran5 amd64 15-20250222-0ubuntu1 [919 kB] 170s Get:19 http://ftpmaster.internal/ubuntu plucky/main amd64 libgomp1 amd64 15-20250222-0ubuntu1 [148 kB] 170s Get:20 http://ftpmaster.internal/ubuntu plucky/main amd64 libgraphite2-3 amd64 1.3.14-2ubuntu1 [73.1 kB] 170s Get:21 http://ftpmaster.internal/ubuntu plucky/main amd64 libharfbuzz0b amd64 10.2.0-1 [543 kB] 170s Get:22 http://ftpmaster.internal/ubuntu plucky/main amd64 x11-common all 1:7.7+23ubuntu3 [21.7 kB] 170s Get:23 http://ftpmaster.internal/ubuntu plucky/main amd64 libice6 amd64 2:1.1.1-1 [44.1 kB] 170s Get:24 http://ftpmaster.internal/ubuntu plucky/main amd64 libjpeg-turbo8 amd64 2.1.5-3ubuntu2 [179 kB] 170s Get:25 http://ftpmaster.internal/ubuntu plucky/main amd64 libjpeg8 amd64 8c-2ubuntu11 [2148 B] 170s Get:26 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-bootstrap all 3.4.1+dfsg-3 [129 kB] 170s Get:27 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-popper.js all 1.16.1+ds-6 [54.1 kB] 170s Get:28 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-bootstrap4 all 4.6.1+dfsg1-4 [537 kB] 170s Get:29 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-d3 all 3.5.17-4 [132 kB] 170s Get:30 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-es5-shim all 4.6.7-2 [39.8 kB] 170s Get:31 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-highlight.js all 9.18.5+dfsg1-2 [385 kB] 170s Get:32 http://ftpmaster.internal/ubuntu plucky/main amd64 libjs-jquery all 3.6.1+dfsg+~3.5.14-1 [328 kB] 170s Get:33 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-jquery-datatables all 1.11.5+dfsg-2 [146 kB] 170s Get:34 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-sifter.js all 0.6.0+dfsg-3 [12.6 kB] 170s Get:35 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-microplugin.js all 0.0.3+dfsg-1.1 [3712 B] 170s Get:36 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-jquery-selectize.js all 0.12.6+dfsg-1.1 [51.0 kB] 170s Get:37 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-jquery-ui all 1.13.2+dfsg-1 [252 kB] 170s Get:38 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-json all 0~20221030+~1.0.8-1 [20.6 kB] 170s Get:39 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-prettify all 2015.12.04+dfsg-1.1 [39.3 kB] 170s Get:40 http://ftpmaster.internal/ubuntu plucky/main amd64 liblapack3 amd64 3.12.1-2 [3179 kB] 170s Get:41 http://ftpmaster.internal/ubuntu plucky/main amd64 liblerc4 amd64 4.0.0+ds-5ubuntu1 [271 kB] 170s Get:42 http://ftpmaster.internal/ubuntu plucky/main amd64 liblua5.4-0 amd64 5.4.7-1 [196 kB] 170s Get:43 http://ftpmaster.internal/ubuntu plucky/main amd64 libthai-data all 0.1.29-2build1 [158 kB] 170s Get:44 http://ftpmaster.internal/ubuntu plucky/main amd64 libthai0 amd64 0.1.29-2build1 [18.9 kB] 170s Get:45 http://ftpmaster.internal/ubuntu plucky/main amd64 libpango-1.0-0 amd64 1.56.2-1 [255 kB] 170s Get:46 http://ftpmaster.internal/ubuntu plucky/main amd64 libpangoft2-1.0-0 amd64 1.56.2-1 [52.6 kB] 170s Get:47 http://ftpmaster.internal/ubuntu plucky/main amd64 libpangocairo-1.0-0 amd64 1.56.2-1 [29.1 kB] 170s Get:48 http://ftpmaster.internal/ubuntu plucky/main amd64 libpaper2 amd64 2.2.5-0.3 [17.4 kB] 170s Get:49 http://ftpmaster.internal/ubuntu plucky/main amd64 libpaper-utils amd64 2.2.5-0.3 [15.5 kB] 170s Get:50 http://ftpmaster.internal/ubuntu plucky/main amd64 libsharpyuv0 amd64 1.5.0-0.1 [25.9 kB] 170s Get:51 http://ftpmaster.internal/ubuntu plucky/main amd64 libsm6 amd64 2:1.2.4-1 [17.4 kB] 170s Get:52 http://ftpmaster.internal/ubuntu plucky/main amd64 libtcl8.6 amd64 8.6.16+dfsg-1 [1086 kB] 170s Get:53 http://ftpmaster.internal/ubuntu plucky/main amd64 libjbig0 amd64 2.1-6.1ubuntu2 [29.7 kB] 170s Get:54 http://ftpmaster.internal/ubuntu plucky/main amd64 libwebp7 amd64 1.5.0-0.1 [378 kB] 170s Get:55 http://ftpmaster.internal/ubuntu plucky/main amd64 libtiff6 amd64 4.5.1+git230720-4ubuntu4 [200 kB] 170s Get:56 http://ftpmaster.internal/ubuntu plucky/main amd64 libxft2 amd64 2.3.6-1build1 [45.3 kB] 170s Get:57 http://ftpmaster.internal/ubuntu plucky/main amd64 libxss1 amd64 1:1.2.3-1build3 [7204 B] 170s Get:58 http://ftpmaster.internal/ubuntu plucky/main amd64 libtk8.6 amd64 8.6.16-1 [868 kB] 170s Get:59 http://ftpmaster.internal/ubuntu plucky/main amd64 libxt6t64 amd64 1:1.2.1-1.2build1 [171 kB] 170s Get:60 http://ftpmaster.internal/ubuntu plucky/main amd64 zip amd64 3.0-14ubuntu2 [185 kB] 170s Get:61 http://ftpmaster.internal/ubuntu plucky/main amd64 unzip amd64 6.0-28ubuntu6 [181 kB] 170s Get:62 http://ftpmaster.internal/ubuntu plucky/main amd64 xdg-utils all 1.2.1-2ubuntu1 [66.0 kB] 170s Get:63 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-base-core amd64 4.4.3-1 [28.9 MB] 170s Get:64 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-littler amd64 0.3.20-2 [96.6 kB] 170s Get:65 http://ftpmaster.internal/ubuntu plucky/universe amd64 littler all 0.3.20-2 [2554 B] 170s Get:66 http://ftpmaster.internal/ubuntu plucky/universe amd64 node-bootstrap-sass all 3.4.3-2 [187 kB] 170s Get:67 http://ftpmaster.internal/ubuntu plucky/universe amd64 node-html5shiv all 3.7.3+dfsg-5 [13.5 kB] 170s Get:68 http://ftpmaster.internal/ubuntu plucky/universe amd64 node-normalize.css all 8.0.1-5 [10.8 kB] 170s Get:69 http://ftpmaster.internal/ubuntu plucky/universe amd64 pandoc-data all 3.1.11.1-3build1 [78.8 kB] 170s Get:70 http://ftpmaster.internal/ubuntu plucky/universe amd64 pandoc amd64 3.1.11.1+ds-2 [27.2 MB] 170s Get:71 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-base64enc amd64 0.1-3-3 [27.6 kB] 170s Get:72 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-brio amd64 1.1.5-1 [39.0 kB] 170s Get:73 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rlang amd64 1.1.5-1 [1719 kB] 170s Get:74 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-fastmap amd64 1.2.0-1 [73.8 kB] 170s Get:75 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-cachem amd64 1.1.0-1 [74.1 kB] 170s Get:76 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-digest amd64 0.6.37-1 [200 kB] 170s Get:77 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-htmltools amd64 0.5.8.1-1 [373 kB] 170s Get:78 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-jquerylib all 0.1.4+dfsg-4 [13.5 kB] 170s Get:79 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-jsonlite amd64 1.9.1+dfsg-1 [447 kB] 170s Get:80 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-cli amd64 3.6.4-1 [1394 kB] 170s Get:81 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-glue amd64 1.8.0-1 [164 kB] 170s Get:82 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-lifecycle all 1.0.4+dfsg-1 [110 kB] 170s Get:83 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-memoise all 2.0.1-1 [53.9 kB] 170s Get:84 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-mime amd64 0.12-2 [35.8 kB] 170s Get:85 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-fs amd64 1.6.5+dfsg-1 [246 kB] 170s Get:86 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-r6 all 2.6.1-1 [101 kB] 170s Get:87 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rappdirs amd64 0.3.3-1 [47.5 kB] 170s Get:88 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-sass amd64 0.4.9+dfsg-1 [1001 kB] 170s Get:89 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-bslib all 0.8.0+dfsg-1 [4294 kB] 170s Get:90 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-ps amd64 1.9.0-1 [408 kB] 170s Get:91 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-processx amd64 3.8.6-1 [365 kB] 170s Get:92 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-callr all 3.7.6-1 [458 kB] 170s Get:93 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-codetools all 0.2-20-1 [90.5 kB] 170s Get:94 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-colorspace amd64 2.1-1+dfsg-1 [1563 kB] 170s Get:95 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-commonmark amd64 1.9.2-2 [137 kB] 170s Get:96 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-crayon all 1.5.3-1 [165 kB] 170s Get:97 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-desc all 1.4.3-1 [359 kB] 170s Get:98 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-diffobj amd64 0.3.5-1 [1117 kB] 170s Get:99 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-gtable all 0.3.6+dfsg-1 [199 kB] 170s Get:100 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-isoband amd64 0.2.7-1 [1481 kB] 170s Get:101 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-mass amd64 7.3-64-1 [1114 kB] 170s Get:102 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-lattice amd64 0.22-6-1 [1340 kB] 170s Get:103 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-nlme amd64 3.1.167-1 [2320 kB] 170s Get:104 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-matrix amd64 1.7-3-1 [4349 kB] 171s Get:105 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-mgcv amd64 1.9-1-1 [3252 kB] 171s Get:106 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-farver amd64 2.1.2-1 [1355 kB] 171s Get:107 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-labeling all 0.4.3-1 [62.1 kB] 171s Get:108 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-munsell all 0.5.1-1 [213 kB] 171s Get:109 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rcolorbrewer all 1.1-3-1build1 [55.4 kB] 171s Get:110 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-viridislite all 0.4.2-2 [1088 kB] 171s Get:111 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-scales all 1.3.0-1 [603 kB] 171s Get:112 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-fansi amd64 1.0.5-1 [619 kB] 171s Get:113 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-magrittr amd64 2.0.3-1 [154 kB] 171s Get:114 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-utf8 amd64 1.2.4-1 [140 kB] 171s Get:115 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-vctrs amd64 0.6.5-1 [1335 kB] 171s Get:116 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-pillar all 1.10.1+dfsg-1 [453 kB] 171s Get:117 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-pkgconfig all 2.0.3-2build1 [19.7 kB] 171s Get:118 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-tibble amd64 3.2.1+dfsg-3 [419 kB] 171s Get:119 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-withr all 3.0.2+dfsg-1 [214 kB] 171s Get:120 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-ggplot2 all 3.5.1+dfsg-1 [3940 kB] 171s Get:121 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-mvtnorm amd64 1.3-3-1 [923 kB] 171s Get:122 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-dosefinding amd64 1.3-1-1 [973 kB] 171s Get:123 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-evaluate all 1.0.3-1 [114 kB] 171s Get:124 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-fontawesome all 0.5.3-1 [1331 kB] 171s Get:125 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-xfun amd64 0.51+dfsg-1 [574 kB] 171s Get:126 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-highr all 0.11+dfsg-1 [38.5 kB] 171s Get:127 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-pkgkitten all 0.2.4-1 [27.2 kB] 171s Get:128 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rcpp amd64 1.0.14-1 [1998 kB] 171s Get:129 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-later amd64 1.4.1+dfsg-1 [154 kB] 171s Get:130 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-promises amd64 1.3.2+dfsg-1 [291 kB] 171s Get:131 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-httpuv amd64 1.6.15+dfsg-1 [510 kB] 171s Get:132 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-yaml amd64 2.3.10-1 [109 kB] 171s Get:133 http://ftpmaster.internal/ubuntu plucky/main amd64 libjs-mathjax all 2.7.9+dfsg-1 [5665 kB] 171s Get:134 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-knitr all 1.49+dfsg-1 [859 kB] 171s Get:135 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-survival amd64 3.8-3-1 [8239 kB] 171s Get:136 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-th.data all 1.1-3-1 [8723 kB] 171s Get:137 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-zoo amd64 1.8-13-1 [999 kB] 171s Get:138 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-sandwich all 3.1-1-1 [1483 kB] 171s Get:139 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-multcomp all 1.4-28-1 [700 kB] 171s Get:140 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-numderiv all 2016.8-1.1-3 [115 kB] 171s Get:141 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-pkgbuild all 1.4.6-1 [213 kB] 171s Get:142 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rprojroot all 2.0.4-2 [125 kB] 171s Get:143 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-pkgload all 1.4.0-1 [247 kB] 171s Get:144 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-praise all 1.0.0-4build1 [20.3 kB] 171s Get:145 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-quadprog amd64 1.5-8-1build1 [30.9 kB] 171s Get:146 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-tinytex all 0.56-1 [148 kB] 171s Get:147 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-modernizr all 3.13.0-0.1 [101 kB] 171s Get:148 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-xtable all 1:1.8-4-2 [689 kB] 171s Get:149 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-sourcetools amd64 0.1.7-1-1 [48.1 kB] 171s Get:150 http://ftpmaster.internal/ubuntu plucky/universe amd64 libjs-twitter-bootstrap-datepicker all 1.3.1+dfsg1-4.1 [28.5 kB] 171s Get:151 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-shiny all 1.10.0+dfsg-2 [3124 kB] 171s Get:152 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rmarkdown all 2.29+dfsg-1 [1501 kB] 171s Get:153 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-truncnorm amd64 1.0-9-2 [25.3 kB] 171s Get:154 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-rsolnp all 1.16+dfsg-4build1 [249 kB] 171s Get:155 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-waldo all 0.6.1-2 [150 kB] 171s Get:156 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-cran-testthat amd64 3.2.3-1 [1651 kB] 172s Preconfiguring packages ... 172s Fetched 156 MB in 1s (118 MB/s) 172s Selecting previously unselected package fonts-dejavu-mono. 172s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 76968 files and directories currently installed.) 172s Preparing to unpack .../000-fonts-dejavu-mono_2.37-8_all.deb ... 172s Unpacking fonts-dejavu-mono (2.37-8) ... 172s Selecting previously unselected package fonts-dejavu-core. 172s Preparing to unpack .../001-fonts-dejavu-core_2.37-8_all.deb ... 172s Unpacking fonts-dejavu-core (2.37-8) ... 172s Selecting previously unselected package fontconfig-config. 172s Preparing to unpack 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previously unselected package r-cran-crayon. 177s Preparing to unpack .../095-r-cran-crayon_1.5.3-1_all.deb ... 177s Unpacking r-cran-crayon (1.5.3-1) ... 177s Selecting previously unselected package r-cran-desc. 177s Preparing to unpack .../096-r-cran-desc_1.4.3-1_all.deb ... 177s Unpacking r-cran-desc (1.4.3-1) ... 177s Selecting previously unselected package r-cran-diffobj. 177s Preparing to unpack .../097-r-cran-diffobj_0.3.5-1_amd64.deb ... 177s Unpacking r-cran-diffobj (0.3.5-1) ... 177s Selecting previously unselected package r-cran-gtable. 177s Preparing to unpack .../098-r-cran-gtable_0.3.6+dfsg-1_all.deb ... 177s Unpacking r-cran-gtable (0.3.6+dfsg-1) ... 177s Selecting previously unselected package r-cran-isoband. 177s Preparing to unpack .../099-r-cran-isoband_0.2.7-1_amd64.deb ... 177s Unpacking r-cran-isoband (0.2.7-1) ... 177s Selecting previously unselected package r-cran-mass. 177s Preparing to unpack .../100-r-cran-mass_7.3-64-1_amd64.deb ... 177s Unpacking r-cran-mass (7.3-64-1) ... 177s Selecting previously unselected package r-cran-lattice. 177s Preparing to unpack .../101-r-cran-lattice_0.22-6-1_amd64.deb ... 177s Unpacking r-cran-lattice (0.22-6-1) ... 177s Selecting previously unselected package r-cran-nlme. 177s Preparing to unpack .../102-r-cran-nlme_3.1.167-1_amd64.deb ... 177s Unpacking r-cran-nlme (3.1.167-1) ... 177s Selecting previously unselected package r-cran-matrix. 177s Preparing to unpack .../103-r-cran-matrix_1.7-3-1_amd64.deb ... 177s Unpacking r-cran-matrix (1.7-3-1) ... 177s Selecting previously unselected package r-cran-mgcv. 177s Preparing to unpack .../104-r-cran-mgcv_1.9-1-1_amd64.deb ... 177s Unpacking r-cran-mgcv (1.9-1-1) ... 177s Selecting previously unselected package r-cran-farver. 177s Preparing to unpack .../105-r-cran-farver_2.1.2-1_amd64.deb ... 177s Unpacking r-cran-farver (2.1.2-1) ... 177s Selecting previously unselected package r-cran-labeling. 177s Preparing to unpack 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previously unselected package r-cran-magrittr. 178s Preparing to unpack .../112-r-cran-magrittr_2.0.3-1_amd64.deb ... 178s Unpacking r-cran-magrittr (2.0.3-1) ... 178s Selecting previously unselected package r-cran-utf8. 178s Preparing to unpack .../113-r-cran-utf8_1.2.4-1_amd64.deb ... 178s Unpacking r-cran-utf8 (1.2.4-1) ... 178s Selecting previously unselected package r-cran-vctrs. 178s Preparing to unpack .../114-r-cran-vctrs_0.6.5-1_amd64.deb ... 178s Unpacking r-cran-vctrs (0.6.5-1) ... 178s Selecting previously unselected package r-cran-pillar. 178s Preparing to unpack .../115-r-cran-pillar_1.10.1+dfsg-1_all.deb ... 178s Unpacking r-cran-pillar (1.10.1+dfsg-1) ... 178s Selecting previously unselected package r-cran-pkgconfig. 178s Preparing to unpack .../116-r-cran-pkgconfig_2.0.3-2build1_all.deb ... 178s Unpacking r-cran-pkgconfig (2.0.3-2build1) ... 178s Selecting previously unselected package r-cran-tibble. 178s Preparing to unpack .../117-r-cran-tibble_3.2.1+dfsg-3_amd64.deb 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r-cran-fontawesome. 178s Preparing to unpack .../123-r-cran-fontawesome_0.5.3-1_all.deb ... 178s Unpacking r-cran-fontawesome (0.5.3-1) ... 178s Selecting previously unselected package r-cran-xfun. 178s Preparing to unpack .../124-r-cran-xfun_0.51+dfsg-1_amd64.deb ... 178s Unpacking r-cran-xfun (0.51+dfsg-1) ... 178s Selecting previously unselected package r-cran-highr. 178s Preparing to unpack .../125-r-cran-highr_0.11+dfsg-1_all.deb ... 178s Unpacking r-cran-highr (0.11+dfsg-1) ... 178s Selecting previously unselected package r-cran-pkgkitten. 178s Preparing to unpack .../126-r-cran-pkgkitten_0.2.4-1_all.deb ... 178s Unpacking r-cran-pkgkitten (0.2.4-1) ... 178s Selecting previously unselected package r-cran-rcpp. 178s Preparing to unpack .../127-r-cran-rcpp_1.0.14-1_amd64.deb ... 178s Unpacking r-cran-rcpp (1.0.14-1) ... 178s Selecting previously unselected package r-cran-later. 178s Preparing to unpack .../128-r-cran-later_1.4.1+dfsg-1_amd64.deb ... 178s Unpacking r-cran-later 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(0.4.9+dfsg-1) ... 184s Setting up r-cran-vctrs (0.6.5-1) ... 184s Setting up r-cran-pillar (1.10.1+dfsg-1) ... 184s Setting up r-cran-callr (3.7.6-1) ... 184s Setting up r-cran-desc (1.4.3-1) ... 184s Setting up r-cran-munsell (0.5.1-1) ... 184s Setting up r-cran-tibble (3.2.1+dfsg-3) ... 184s Setting up r-cran-sandwich (3.1-1-1) ... 184s Setting up r-cran-fontawesome (0.5.3-1) ... 184s Setting up r-cran-survival (3.8-3-1) ... 184s Setting up r-cran-jquerylib (0.1.4+dfsg-4) ... 184s Setting up r-cran-th.data (1.1-3-1) ... 184s Setting up r-cran-scales (1.3.0-1) ... 184s Setting up r-cran-memoise (2.0.1-1) ... 184s Setting up r-cran-promises (1.3.2+dfsg-1) ... 184s Setting up r-cran-multcomp (1.4-28-1) ... 184s Setting up r-cran-pkgbuild (1.4.6-1) ... 184s Setting up r-cran-pkgload (1.4.0-1) ... 184s Setting up r-cran-ggplot2 (3.5.1+dfsg-1) ... 184s Setting up r-cran-httpuv (1.6.15+dfsg-1) ... 184s Setting up r-cran-testthat (3.2.3-1) ... 184s Setting up r-cran-bslib (0.8.0+dfsg-1) ... 184s Setting up r-cran-dosefinding (1.3-1-1) ... 184s Setting up r-cran-shiny (1.10.0+dfsg-2) ... 184s Setting up r-cran-rmarkdown (2.29+dfsg-1) ... 184s Processing triggers for libc-bin (2.41-1ubuntu2) ... 184s Processing triggers for man-db (2.13.0-1) ... 185s Processing triggers for install-info (7.1.1-1) ... 186s autopkgtest [22:09:12]: test run-unit-test: [----------------------- 186s Loading required package: DoseFinding 187s Dose Response Model 187s 187s Model: linear 187s Fit-type: general 187s 187s Coefficients dose-response model 187s delta 187s 0.07484 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 3.472 187s Dose Response Model 187s 187s Model: linear 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 delta 187s 0.33400 0.07484 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 3.472 187s Dose Response Model 187s 187s Model: quadratic 187s Fit-type: general 187s 187s Coefficients dose-response model 187s b1 b2 187s 0.22800 -0.03811 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.9281 187s Dose Response Model 187s 187s Model: quadratic 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 b1 b2 187s 0.24950 0.22800 -0.03811 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.9281 187s Dose Response Model 187s 187s Model: linlog 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 delta 187s 0.47790 0.07728 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.1605 187s Dose Response Model 187s 187s Model: emax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s eMax ed50 187s 0.3771 0.3630 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.09815 187s Dose Response Model 187s 187s Model: emax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax ed50 187s 0.2221 0.3771 0.3630 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.09815 187s Dose Response Model 187s 187s Model: sigEmax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s eMax ed50 h 187s 0.4714 0.4880 0.5000 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.07825 187s Dose Response Model 187s 187s Model: sigEmax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax ed50 h 187s 0.2223 0.4714 0.4880 0.5000 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.07825 187s Dose Response Model 187s 187s Model: exponential 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e1 delta 187s 0.4391 8.0000 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 4.102 187s Dose Response Model 187s 187s Model: exponential 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 e1 delta 187s 0.3510 0.4391 8.0000 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 4.102 187s Dose Response Model 187s 187s Model: logistic 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax ed50 delta 187s -0.1095 0.6665 0.0040 0.4217 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.1951 187s Dose Response Model 187s 187s Model: betaMod 187s Fit-type: general 187s 187s Coefficients dose-response model 187s eMax delta1 delta2 187s 0.3468 0.2216 0.0500 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.0783 187s Dose Response Model 187s 187s Model: betaMod 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax delta1 delta2 187s 0.2222 0.3468 0.2216 0.0500 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.0783 187s Dose Response Model 187s 187s Model: linInt 187s Fit-type: general 187s 187s Coefficients dose-response model 187s d1 d2 d3 d4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0 187s Dose Response Model 187s 187s Model: linInt 187s Fit-type: general 187s 187s Coefficients dose-response model 187s d0 d1 d2 d3 d4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 1.484e-30 187s Dose Response Model 187s 187s Model: emax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s eMax ed50 187s 0.3771 0.3630 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.09815 187s Dose Response Model 187s 187s Model: emax 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax ed50 187s 0.2221 0.3771 0.3630 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.09815 187s Dose Response Model 187s 187s Model: betaMod 187s Fit-type: general 187s 187s Coefficients dose-response model 187s eMax delta1 delta2 187s 0.3468 0.2216 0.0500 187s 187s Fitted to: 187s 1 2 3 4 187s 0.2846 0.2965 0.3502 0.3480 187s 187s Generalized residual sum of squares: 0.0783 187s Dose Response Model 187s 187s Model: betaMod 187s Fit-type: general 187s 187s Coefficients dose-response model 187s e0 eMax delta1 delta2 187s 0.2222 0.3468 0.2216 0.0500 187s 187s Fitted to: 187s 0 1 2 3 4 187s 0.2220 0.5065 0.5185 0.5722 0.5700 187s 187s Generalized residual sum of squares: 0.0783 187s $fit 187s [1] 0.0000000 0.2756421 0.3165257 0.3387105 0.3466573 187s 187s $se.fit 187s [1] 0.0000000 0.1235753 0.1106156 0.1135736 0.1263900 187s 187s $fit 187s [1] 0.2756421 0.3165257 0.3387105 0.3466573 187s 187s $se.fit 187s [1] 0.1235753 0.1106156 0.1135736 0.1263900 187s 187s e0 eMax delta1 delta2 187s e0 0.0118410628 -0.008186899 0.003722514 -0.0008419768 187s eMax -0.0081868987 0.014334651 -0.016984400 -0.0239850502 187s delta1 0.0037225143 -0.016984400 0.475384247 0.3641344062 187s delta2 -0.0008419768 -0.023985050 0.364134406 0.3356088151 187s eMax delta1 delta2 187s eMax 0.01433465 -0.0169844 -0.02398505 187s delta1 -0.01698440 0.4753842 0.36413441 187s delta2 -0.02398505 0.3641344 0.33560882 187s Message: Setting predType to "ls-means" for "type = general" 187s $fit 187s [1] 0.2219856 0.5065390 0.5185323 0.5721580 0.5699850 187s 187s $se.fit 187s [1] 0.1088272 0.1048057 0.1044027 0.1046862 0.1088405 187s 187s $fit 187s [1] 0.0000000 0.2845534 0.2965467 0.3501724 0.3479994 187s 187s $se.fit 187s [1] 0.0000000 0.1252903 0.1265494 0.1279290 0.1273279 187s 187s $fit 187s [1] 0.2845534 0.2965467 0.3501724 0.3479994 187s 187s $se.fit 187s [1] 0.1252903 0.1265494 0.1279290 0.1273279 187s 187s Message: Setting predType to "effect-curve" for placebo-adjusted data 187s d0 d1 d2 d3 d4 187s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 187s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 187s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 187s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 187s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 187s d1 d2 d3 d4 187s d1 0.015697662 0.008221459 0.008223928 0.008215124 187s d2 0.008221459 0.016014746 0.008246506 0.008208911 187s d3 0.008223928 0.008246506 0.016365819 0.008204394 187s d4 0.008215124 0.008208911 0.008204394 0.016212400 187s d0 d1 d2 d3 d4 187s d0 0.011843358 0.003564965 0.003364270 0.003218371 0.003738601 187s d1 0.003564965 0.010984234 0.003307337 0.003163906 0.003675332 187s d2 0.003364270 0.003307337 0.010899929 0.002985790 0.003468425 187s d3 0.003218371 0.003163906 0.002985790 0.010959203 0.003318008 187s d4 0.003738601 0.003675332 0.003468425 0.003318008 0.011846244 187s gender2 -0.005149393 -0.005062250 -0.004777264 -0.004570087 -0.005308813 187s gender2 187s d0 -0.005149393 187s d1 -0.005062250 187s d2 -0.004777264 187s d3 -0.004570087 187s d4 -0.005308813 187s gender2 0.007312139 187s d0 d1 d2 d3 d4 187s d0 0.00819461 0.000000000 0.000000000 0.000000000 0.0000000 187s d1 0.00000000 0.007459197 0.000000000 0.000000000 0.0000000 187s d2 0.00000000 0.000000000 0.007757564 0.000000000 0.0000000 187s d3 0.00000000 0.000000000 0.000000000 0.008080796 0.0000000 187s d4 0.00000000 0.000000000 0.000000000 0.000000000 0.0079701 187s d1 d2 d3 d4 187s d1 0.015697662 0.008221459 0.008223928 0.008215124 187s d2 0.008221459 0.016014746 0.008246506 0.008208911 187s d3 0.008223928 0.008246506 0.016365819 0.008204394 187s d4 0.008215124 0.008208911 0.008204394 0.016212400 187s $fit 187s [1] 0.2845534 0.2965467 0.3501724 0.3479994 187s 187s $se.fit 187s [1] 0.1252903 0.1265494 0.1279290 0.1273279 187s 187s testgFit.R passed 187s testplanMod.R passed 187s Loading required package: DoseFinding 188s [1] 0.5099184 188s Calculated TD - optimal design: 188s 0 18.75 188s 0.50003 0.49997 188s Calculated TD - optimal design: 188s 0 104.52 188s 0.49993 0.50006 188s [1] 0.4286171 188s Calculated TD - optimal design: 188s 0 101.57 150 188s 0.43958 0.50000 0.06041 188s Calculated TD - optimal design: 188s 0 37.29 64.44 150 188s 0.40070 0.45303 0.09933 0.04694 188s [1] 0.1853293 188s Calculated TD - optimal design: 188s 0 50.22 188s 0.5 0.5 188s Calculated TD - optimal design: 188s 0 0.49 25.2 108.07 188s 0.44787 0.47652 0.05213 0.02348 188s [1] 0.130092 188s Calculated TD - optimal design: 188s 0 27 94.89 150 188s 0.44879 0.47519 0.05121 0.02481 188s [1] 0.5013672 188s Calculated TD - optimal design: 188s 0 0.35 150 188s 0.49865 0.50000 0.00135 188s [1] 0.05572985 188s [1] 4.478701e-01 4.765233e-01 5.212994e-02 2.347673e-02 6.509032e-09 188s [1] 4.478701e-01 4.765233e-01 5.212991e-02 2.347669e-02 5.680430e-09 189s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 189s [1,] 0.246 0.142 0.122 0.000 0.000 0.241 0 0 0.249 189s [2,] 0.248 0.234 0.059 0.211 0.000 0.000 0 0 0.248 189s [3,] 0.247 0.000 0.000 0.224 0.081 0.203 0 0 0.246 189s [4,] 0.250 0.248 0.044 0.210 0.000 0.000 0 0 0.249 189s [5,] 0.250 0.248 0.191 0.064 0.000 0.000 0 0 0.247 189s [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] 189s [1,] 0.49 0.01 0.00 0.00 0.00 0.00 0.36 0.14 0.00 189s [2,] 0.48 0.02 0.00 0.32 0.18 0.00 0.00 0.00 0.00 189s [3,] 0.21 0.29 0.00 0.00 0.00 0.46 0.04 0.00 0.00 189s [4,] 0.50 0.00 0.49 0.01 0.00 0.00 0.00 0.00 0.00 189s [5,] 0.49 0.02 0.48 0.00 0.00 0.00 0.00 0.00 0.01 189s [1] 0.8823949 189s Calculated D - optimal design: 189s 0 1 189s 0.5 0.5 189s Calculated TD - optimal design: 189s 0 0.25 0.5 1 189s 0.48951 0.35517 0.14483 0.01049 189s testsDesign.R passed 189s Loading required package: DoseFinding 190s [1] 3714.641 190s [1] 3714.641 190s Dose Response Model 190s 190s Model: betaMod 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -23.368 -3.727 0.129 3.894 16.152 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 10.80 0.565 190s eMax 7.41 0.692 190s delta1 2.24 0.589 190s delta2 1.00 0.328 190s 190s Residual standard error: 5.64 190s Degrees of freedom: 585 190s 190s Formula: y ~ betaMod(x, e0, emax, delta1, delta2, 1.2 * max(datset$x)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s e0 10.7964 0.5653 19.098 < 2e-16 *** 190s emax 7.4106 0.6917 10.714 < 2e-16 *** 190s delta1 2.2357 0.5885 3.799 0.000161 *** 190s delta2 1.0047 0.3277 3.066 0.002271 ** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 5.637 on 585 degrees of freedom 190s 190s Number of iterations to convergence: 6 190s Achieved convergence tolerance: 4.028e-06 190s 190s e0 eMax delta1 delta2 190s e0 0.31958673 -0.28252697 0.20809234 0.09247897 190s eMax -0.28252697 0.47843297 -0.04177476 0.01244179 190s delta1 0.20809234 -0.04177476 0.34639417 0.18051781 190s delta2 0.09247897 0.01244179 0.18051781 0.10741016 190s e0 emax delta1 delta2 190s e0 0.31959066 -0.28253052 0.20808969 0.09247786 190s emax -0.28253052 0.47843381 -0.04177516 0.01244118 190s delta1 0.20808969 -0.04177516 0.34638195 0.18051234 190s delta2 0.09247786 0.01244118 0.18051234 0.10740756 190s $fit 190s [1] 6.0578751 6.8058158 7.2227652 6.0578751 3.1444084 6.8058158 7.2227652 190s [8] 3.1444084 6.0578751 0.0000000 6.0578751 6.0578751 7.2227652 3.1444084 190s [15] 0.8440180 0.0000000 6.0578751 3.1444084 3.1444084 0.0000000 7.2227652 190s [22] 0.0000000 7.2227652 6.8058158 6.8058158 3.1444084 6.8058158 6.8058158 190s [29] 3.1444084 6.0578751 7.2227652 6.8058158 3.1444084 3.1444084 3.1444084 190s [36] 0.0000000 0.0000000 3.1444084 6.8058158 3.1444084 3.1444084 0.8440180 190s [43] 3.1444084 6.0578751 3.1444084 6.0578751 0.8440180 7.2227652 0.8440180 190s [50] 0.8440180 0.0000000 7.2227652 6.8058158 6.8058158 7.2227652 3.1444084 190s [57] 7.2227652 6.8058158 0.8440180 0.8440180 3.1444084 0.0000000 7.2227652 190s [64] 6.8058158 6.8058158 6.8058158 0.0000000 7.2227652 3.1444084 6.0578751 190s [71] 0.0000000 0.8440180 0.8440180 6.8058158 3.1444084 3.1444084 6.0578751 190s [78] 0.0000000 6.0578751 6.8058158 6.8058158 3.1444084 3.1444084 3.1444084 190s [85] 3.1444084 7.2227652 6.8058158 0.8440180 0.0000000 0.8440180 7.2227652 190s [92] 6.8058158 3.1444084 7.2227652 6.0578751 6.8058158 6.0578751 6.8058158 190s [99] 6.8058158 6.8058158 3.1444084 6.0578751 6.8058158 0.0000000 6.0578751 190s [106] 6.8058158 0.0000000 6.8058158 3.1444084 3.1444084 0.8440180 6.8058158 190s [113] 6.0578751 3.1444084 0.1731496 6.0578751 6.0578751 0.0000000 6.8058158 190s [120] 0.0000000 0.0000000 6.8058158 0.1731496 0.8440180 0.0000000 6.0578751 190s [127] 6.8058158 3.1444084 6.0578751 0.8440180 6.8058158 0.8440180 7.2227652 190s [134] 6.8058158 3.1444084 6.0578751 6.8058158 7.2227652 6.8058158 0.1731496 190s [141] 6.8058158 6.8058158 0.8440180 6.8058158 6.0578751 7.2227652 6.8058158 190s [148] 3.1444084 3.1444084 0.0000000 6.0578751 3.1444084 0.0000000 3.1444084 190s [155] 6.8058158 7.2227652 6.8058158 0.0000000 0.0000000 0.8440180 3.1444084 190s [162] 0.0000000 0.1731496 3.1444084 3.1444084 6.0578751 0.0000000 0.8440180 190s [169] 0.0000000 3.1444084 3.1444084 6.0578751 6.0578751 0.0000000 7.2227652 190s [176] 0.8440180 0.0000000 6.0578751 0.0000000 7.2227652 0.0000000 3.1444084 190s [183] 6.0578751 6.0578751 3.1444084 3.1444084 0.1731496 7.2227652 3.1444084 190s [190] 0.8440180 7.2227652 7.2227652 0.8440180 0.0000000 7.2227652 3.1444084 190s [197] 7.2227652 7.2227652 0.1731496 3.1444084 0.0000000 7.2227652 3.1444084 190s [204] 6.8058158 6.8058158 7.2227652 6.8058158 7.2227652 0.8440180 6.0578751 190s [211] 3.1444084 3.1444084 3.1444084 0.0000000 0.0000000 6.0578751 6.0578751 190s [218] 3.1444084 3.1444084 0.1731496 7.2227652 7.2227652 0.0000000 0.8440180 190s [225] 7.2227652 0.8440180 3.1444084 0.8440180 0.0000000 7.2227652 3.1444084 190s [232] 6.8058158 6.8058158 3.1444084 0.8440180 6.0578751 0.8440180 0.0000000 190s [239] 0.0000000 6.8058158 7.2227652 6.8058158 6.0578751 3.1444084 7.2227652 190s [246] 6.8058158 3.1444084 7.2227652 0.8440180 0.8440180 7.2227652 6.0578751 190s [253] 0.1731496 7.2227652 6.8058158 6.8058158 7.2227652 6.8058158 6.0578751 190s [260] 6.8058158 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 0.8440180 190s [267] 6.8058158 3.1444084 3.1444084 0.8440180 3.1444084 0.8440180 0.0000000 190s [274] 3.1444084 0.8440180 0.8440180 0.1731496 6.0578751 6.0578751 0.8440180 190s [281] 0.0000000 0.0000000 0.0000000 6.0578751 0.0000000 3.1444084 3.1444084 190s [288] 0.0000000 0.8440180 6.0578751 0.0000000 6.0578751 7.2227652 0.8440180 190s [295] 7.2227652 6.8058158 0.8440180 0.1731496 7.2227652 7.2227652 0.0000000 190s [302] 6.0578751 6.8058158 7.2227652 0.0000000 6.0578751 6.0578751 6.8058158 190s [309] 0.0000000 0.8440180 6.0578751 6.8058158 6.8058158 3.1444084 0.8440180 190s [316] 6.8058158 3.1444084 7.2227652 6.0578751 0.8440180 3.1444084 0.8440180 190s [323] 7.2227652 6.0578751 6.0578751 7.2227652 3.1444084 6.0578751 6.8058158 190s [330] 0.8440180 0.8440180 6.8058158 6.8058158 7.2227652 0.8440180 3.1444084 190s [337] 3.1444084 6.0578751 6.0578751 0.0000000 3.1444084 6.8058158 0.8440180 190s [344] 3.1444084 6.0578751 7.2227652 3.1444084 3.1444084 0.1731496 6.0578751 190s [351] 7.2227652 7.2227652 3.1444084 6.0578751 3.1444084 6.0578751 3.1444084 190s [358] 6.0578751 3.1444084 7.2227652 0.8440180 3.1444084 6.8058158 0.8440180 190s [365] 3.1444084 0.1731496 6.8058158 3.1444084 6.8058158 7.2227652 3.1444084 190s [372] 6.8058158 6.8058158 3.1444084 0.0000000 0.8440180 0.8440180 6.8058158 190s [379] 0.0000000 7.2227652 0.8440180 0.8440180 6.0578751 3.1444084 0.8440180 190s [386] 7.2227652 3.1444084 7.2227652 6.8058158 3.1444084 3.1444084 6.8058158 190s [393] 6.0578751 3.1444084 6.8058158 0.0000000 6.8058158 0.8440180 0.0000000 190s [400] 3.1444084 6.8058158 0.8440180 6.0578751 6.0578751 0.1731496 6.0578751 190s [407] 0.8440180 3.1444084 0.8440180 3.1444084 3.1444084 6.8058158 0.8440180 190s [414] 6.8058158 7.2227652 0.0000000 6.8058158 0.8440180 0.0000000 7.2227652 190s [421] 6.8058158 3.1444084 3.1444084 6.8058158 6.8058158 6.0578751 6.0578751 190s [428] 6.0578751 7.2227652 0.1731496 7.2227652 6.8058158 0.0000000 3.1444084 190s [435] 7.2227652 6.8058158 6.8058158 0.8440180 0.0000000 3.1444084 7.2227652 190s [442] 6.8058158 6.0578751 3.1444084 6.0578751 7.2227652 6.0578751 7.2227652 190s [449] 0.0000000 7.2227652 7.2227652 0.8440180 6.0578751 6.8058158 0.0000000 190s [456] 0.8440180 6.0578751 0.1731496 3.1444084 7.2227652 7.2227652 6.0578751 190s [463] 6.0578751 3.1444084 0.1731496 7.2227652 6.8058158 0.8440180 0.0000000 190s [470] 0.8440180 6.8058158 6.8058158 7.2227652 6.0578751 7.2227652 0.8440180 190s [477] 3.1444084 7.2227652 7.2227652 0.1731496 3.1444084 7.2227652 7.2227652 190s [484] 3.1444084 6.8058158 0.0000000 7.2227652 6.0578751 0.8440180 3.1444084 190s [491] 7.2227652 7.2227652 6.0578751 3.1444084 7.2227652 6.0578751 0.0000000 190s [498] 0.8440180 6.0578751 6.8058158 3.1444084 6.0578751 0.0000000 7.2227652 190s [505] 3.1444084 0.0000000 0.8440180 7.2227652 6.8058158 6.8058158 3.1444084 190s [512] 6.8058158 0.1731496 0.0000000 3.1444084 3.1444084 3.1444084 6.8058158 190s [519] 6.8058158 0.0000000 6.8058158 6.8058158 3.1444084 7.2227652 3.1444084 190s [526] 0.8440180 0.8440180 7.2227652 6.0578751 6.0578751 3.1444084 6.8058158 190s [533] 7.2227652 6.0578751 6.8058158 3.1444084 3.1444084 3.1444084 7.2227652 190s [540] 0.0000000 0.0000000 6.8058158 3.1444084 0.1731496 0.0000000 6.0578751 190s [547] 7.2227652 6.0578751 6.0578751 7.2227652 6.0578751 6.0578751 6.8058158 190s [554] 0.0000000 0.0000000 3.1444084 6.0578751 7.2227652 7.2227652 3.1444084 190s [561] 3.1444084 6.8058158 7.2227652 6.8058158 6.8058158 0.0000000 6.8058158 190s [568] 3.1444084 7.2227652 0.8440180 0.0000000 3.1444084 0.8440180 6.8058158 190s [575] 7.2227652 3.1444084 6.0578751 0.8440180 6.8058158 3.1444084 0.0000000 190s [582] 7.2227652 6.8058158 0.8440180 6.0578751 3.1444084 6.8058158 0.8440180 190s [589] 6.0578751 190s 190s $se.fit 190s [1] 0.7643614 0.6580335 0.7488551 0.7643614 0.7997224 0.6580335 0.7488551 190s [8] 0.7997224 0.7643614 0.0000000 0.7643614 0.7643614 0.7488551 0.7997224 190s [15] 0.4790120 0.0000000 0.7643614 0.7997224 0.7997224 0.0000000 0.7488551 190s [22] 0.0000000 0.7488551 0.6580335 0.6580335 0.7997224 0.6580335 0.6580335 190s [29] 0.7997224 0.7643614 0.7488551 0.6580335 0.7997224 0.7997224 0.7997224 190s [36] 0.0000000 0.0000000 0.7997224 0.6580335 0.7997224 0.7997224 0.4790120 190s [43] 0.7997224 0.7643614 0.7997224 0.7643614 0.4790120 0.7488551 0.4790120 190s [50] 0.4790120 0.0000000 0.7488551 0.6580335 0.6580335 0.7488551 0.7997224 190s [57] 0.7488551 0.6580335 0.4790120 0.4790120 0.7997224 0.0000000 0.7488551 190s [64] 0.6580335 0.6580335 0.6580335 0.0000000 0.7488551 0.7997224 0.7643614 190s [71] 0.0000000 0.4790120 0.4790120 0.6580335 0.7997224 0.7997224 0.7643614 190s [78] 0.0000000 0.7643614 0.6580335 0.6580335 0.7997224 0.7997224 0.7997224 190s [85] 0.7997224 0.7488551 0.6580335 0.4790120 0.0000000 0.4790120 0.7488551 190s [92] 0.6580335 0.7997224 0.7488551 0.7643614 0.6580335 0.7643614 0.6580335 190s [99] 0.6580335 0.6580335 0.7997224 0.7643614 0.6580335 0.0000000 0.7643614 190s [106] 0.6580335 0.0000000 0.6580335 0.7997224 0.7997224 0.4790120 0.6580335 190s [113] 0.7643614 0.7997224 0.1680259 0.7643614 0.7643614 0.0000000 0.6580335 190s [120] 0.0000000 0.0000000 0.6580335 0.1680259 0.4790120 0.0000000 0.7643614 190s [127] 0.6580335 0.7997224 0.7643614 0.4790120 0.6580335 0.4790120 0.7488551 190s [134] 0.6580335 0.7997224 0.7643614 0.6580335 0.7488551 0.6580335 0.1680259 190s [141] 0.6580335 0.6580335 0.4790120 0.6580335 0.7643614 0.7488551 0.6580335 190s [148] 0.7997224 0.7997224 0.0000000 0.7643614 0.7997224 0.0000000 0.7997224 190s [155] 0.6580335 0.7488551 0.6580335 0.0000000 0.0000000 0.4790120 0.7997224 190s [162] 0.0000000 0.1680259 0.7997224 0.7997224 0.7643614 0.0000000 0.4790120 190s [169] 0.0000000 0.7997224 0.7997224 0.7643614 0.7643614 0.0000000 0.7488551 190s [176] 0.4790120 0.0000000 0.7643614 0.0000000 0.7488551 0.0000000 0.7997224 190s [183] 0.7643614 0.7643614 0.7997224 0.7997224 0.1680259 0.7488551 0.7997224 190s [190] 0.4790120 0.7488551 0.7488551 0.4790120 0.0000000 0.7488551 0.7997224 190s [197] 0.7488551 0.7488551 0.1680259 0.7997224 0.0000000 0.7488551 0.7997224 190s [204] 0.6580335 0.6580335 0.7488551 0.6580335 0.7488551 0.4790120 0.7643614 190s [211] 0.7997224 0.7997224 0.7997224 0.0000000 0.0000000 0.7643614 0.7643614 190s [218] 0.7997224 0.7997224 0.1680259 0.7488551 0.7488551 0.0000000 0.4790120 190s [225] 0.7488551 0.4790120 0.7997224 0.4790120 0.0000000 0.7488551 0.7997224 190s [232] 0.6580335 0.6580335 0.7997224 0.4790120 0.7643614 0.4790120 0.0000000 190s [239] 0.0000000 0.6580335 0.7488551 0.6580335 0.7643614 0.7997224 0.7488551 190s [246] 0.6580335 0.7997224 0.7488551 0.4790120 0.4790120 0.7488551 0.7643614 190s [253] 0.1680259 0.7488551 0.6580335 0.6580335 0.7488551 0.6580335 0.7643614 190s [260] 0.6580335 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.4790120 190s [267] 0.6580335 0.7997224 0.7997224 0.4790120 0.7997224 0.4790120 0.0000000 190s [274] 0.7997224 0.4790120 0.4790120 0.1680259 0.7643614 0.7643614 0.4790120 190s [281] 0.0000000 0.0000000 0.0000000 0.7643614 0.0000000 0.7997224 0.7997224 190s [288] 0.0000000 0.4790120 0.7643614 0.0000000 0.7643614 0.7488551 0.4790120 190s [295] 0.7488551 0.6580335 0.4790120 0.1680259 0.7488551 0.7488551 0.0000000 190s [302] 0.7643614 0.6580335 0.7488551 0.0000000 0.7643614 0.7643614 0.6580335 190s [309] 0.0000000 0.4790120 0.7643614 0.6580335 0.6580335 0.7997224 0.4790120 190s [316] 0.6580335 0.7997224 0.7488551 0.7643614 0.4790120 0.7997224 0.4790120 190s [323] 0.7488551 0.7643614 0.7643614 0.7488551 0.7997224 0.7643614 0.6580335 190s [330] 0.4790120 0.4790120 0.6580335 0.6580335 0.7488551 0.4790120 0.7997224 190s [337] 0.7997224 0.7643614 0.7643614 0.0000000 0.7997224 0.6580335 0.4790120 190s [344] 0.7997224 0.7643614 0.7488551 0.7997224 0.7997224 0.1680259 0.7643614 190s [351] 0.7488551 0.7488551 0.7997224 0.7643614 0.7997224 0.7643614 0.7997224 190s [358] 0.7643614 0.7997224 0.7488551 0.4790120 0.7997224 0.6580335 0.4790120 190s [365] 0.7997224 0.1680259 0.6580335 0.7997224 0.6580335 0.7488551 0.7997224 190s [372] 0.6580335 0.6580335 0.7997224 0.0000000 0.4790120 0.4790120 0.6580335 190s [379] 0.0000000 0.7488551 0.4790120 0.4790120 0.7643614 0.7997224 0.4790120 190s [386] 0.7488551 0.7997224 0.7488551 0.6580335 0.7997224 0.7997224 0.6580335 190s [393] 0.7643614 0.7997224 0.6580335 0.0000000 0.6580335 0.4790120 0.0000000 190s [400] 0.7997224 0.6580335 0.4790120 0.7643614 0.7643614 0.1680259 0.7643614 190s [407] 0.4790120 0.7997224 0.4790120 0.7997224 0.7997224 0.6580335 0.4790120 190s [414] 0.6580335 0.7488551 0.0000000 0.6580335 0.4790120 0.0000000 0.7488551 190s [421] 0.6580335 0.7997224 0.7997224 0.6580335 0.6580335 0.7643614 0.7643614 190s [428] 0.7643614 0.7488551 0.1680259 0.7488551 0.6580335 0.0000000 0.7997224 190s [435] 0.7488551 0.6580335 0.6580335 0.4790120 0.0000000 0.7997224 0.7488551 190s [442] 0.6580335 0.7643614 0.7997224 0.7643614 0.7488551 0.7643614 0.7488551 190s [449] 0.0000000 0.7488551 0.7488551 0.4790120 0.7643614 0.6580335 0.0000000 190s [456] 0.4790120 0.7643614 0.1680259 0.7997224 0.7488551 0.7488551 0.7643614 190s [463] 0.7643614 0.7997224 0.1680259 0.7488551 0.6580335 0.4790120 0.0000000 190s [470] 0.4790120 0.6580335 0.6580335 0.7488551 0.7643614 0.7488551 0.4790120 190s [477] 0.7997224 0.7488551 0.7488551 0.1680259 0.7997224 0.7488551 0.7488551 190s [484] 0.7997224 0.6580335 0.0000000 0.7488551 0.7643614 0.4790120 0.7997224 190s [491] 0.7488551 0.7488551 0.7643614 0.7997224 0.7488551 0.7643614 0.0000000 190s [498] 0.4790120 0.7643614 0.6580335 0.7997224 0.7643614 0.0000000 0.7488551 190s [505] 0.7997224 0.0000000 0.4790120 0.7488551 0.6580335 0.6580335 0.7997224 190s [512] 0.6580335 0.1680259 0.0000000 0.7997224 0.7997224 0.7997224 0.6580335 190s [519] 0.6580335 0.0000000 0.6580335 0.6580335 0.7997224 0.7488551 0.7997224 190s [526] 0.4790120 0.4790120 0.7488551 0.7643614 0.7643614 0.7997224 0.6580335 190s [533] 0.7488551 0.7643614 0.6580335 0.7997224 0.7997224 0.7997224 0.7488551 190s [540] 0.0000000 0.0000000 0.6580335 0.7997224 0.1680259 0.0000000 0.7643614 190s [547] 0.7488551 0.7643614 0.7643614 0.7488551 0.7643614 0.7643614 0.6580335 190s [554] 0.0000000 0.0000000 0.7997224 0.7643614 0.7488551 0.7488551 0.7997224 190s [561] 0.7997224 0.6580335 0.7488551 0.6580335 0.6580335 0.0000000 0.6580335 190s [568] 0.7997224 0.7488551 0.4790120 0.0000000 0.7997224 0.4790120 0.6580335 190s [575] 0.7488551 0.7997224 0.7643614 0.4790120 0.6580335 0.7997224 0.0000000 190s [582] 0.7488551 0.6580335 0.4790120 0.7643614 0.7997224 0.6580335 0.4790120 190s [589] 0.7643614 190s 190s $fit 190s [1] 16.85434 17.60229 18.01923 16.85434 13.94088 17.60229 18.01923 13.94088 190s [9] 16.85434 10.79647 16.85434 16.85434 18.01923 13.94088 11.64049 10.79647 190s [17] 16.85434 13.94088 13.94088 10.79647 18.01923 10.79647 18.01923 17.60229 190s [25] 17.60229 13.94088 17.60229 17.60229 13.94088 16.85434 18.01923 17.60229 190s [33] 13.94088 13.94088 13.94088 10.79647 10.79647 13.94088 17.60229 13.94088 190s [41] 13.94088 11.64049 13.94088 16.85434 13.94088 16.85434 11.64049 18.01923 190s [49] 11.64049 11.64049 10.79647 18.01923 17.60229 17.60229 18.01923 13.94088 190s [57] 18.01923 17.60229 11.64049 11.64049 13.94088 10.79647 18.01923 17.60229 190s [65] 17.60229 17.60229 10.79647 18.01923 13.94088 16.85434 10.79647 11.64049 190s [73] 11.64049 17.60229 13.94088 13.94088 16.85434 10.79647 16.85434 17.60229 190s [81] 17.60229 13.94088 13.94088 13.94088 13.94088 18.01923 17.60229 11.64049 190s [89] 10.79647 11.64049 18.01923 17.60229 13.94088 18.01923 16.85434 17.60229 190s [97] 16.85434 17.60229 17.60229 17.60229 13.94088 16.85434 17.60229 10.79647 190s [105] 16.85434 17.60229 10.79647 17.60229 13.94088 13.94088 11.64049 17.60229 190s [113] 16.85434 13.94088 10.96962 16.85434 16.85434 10.79647 17.60229 10.79647 190s [121] 10.79647 17.60229 10.96962 11.64049 10.79647 16.85434 17.60229 13.94088 190s [129] 16.85434 11.64049 17.60229 11.64049 18.01923 17.60229 13.94088 16.85434 190s [137] 17.60229 18.01923 17.60229 10.96962 17.60229 17.60229 11.64049 17.60229 190s [145] 16.85434 18.01923 17.60229 13.94088 13.94088 10.79647 16.85434 13.94088 190s [153] 10.79647 13.94088 17.60229 18.01923 17.60229 10.79647 10.79647 11.64049 190s [161] 13.94088 10.79647 10.96962 13.94088 13.94088 16.85434 10.79647 11.64049 190s [169] 10.79647 13.94088 13.94088 16.85434 16.85434 10.79647 18.01923 11.64049 190s [177] 10.79647 16.85434 10.79647 18.01923 10.79647 13.94088 16.85434 16.85434 190s [185] 13.94088 13.94088 10.96962 18.01923 13.94088 11.64049 18.01923 18.01923 190s [193] 11.64049 10.79647 18.01923 13.94088 18.01923 18.01923 10.96962 13.94088 190s [201] 10.79647 18.01923 13.94088 17.60229 17.60229 18.01923 17.60229 18.01923 190s [209] 11.64049 16.85434 13.94088 13.94088 13.94088 10.79647 10.79647 16.85434 190s [217] 16.85434 13.94088 13.94088 10.96962 18.01923 18.01923 10.79647 11.64049 190s [225] 18.01923 11.64049 13.94088 11.64049 10.79647 18.01923 13.94088 17.60229 190s [233] 17.60229 13.94088 11.64049 16.85434 11.64049 10.79647 10.79647 17.60229 190s [241] 18.01923 17.60229 16.85434 13.94088 18.01923 17.60229 13.94088 18.01923 190s [249] 11.64049 11.64049 18.01923 16.85434 10.96962 18.01923 17.60229 17.60229 190s [257] 18.01923 17.60229 16.85434 17.60229 11.64049 17.60229 17.60229 18.01923 190s [265] 16.85434 11.64049 17.60229 13.94088 13.94088 11.64049 13.94088 11.64049 190s [273] 10.79647 13.94088 11.64049 11.64049 10.96962 16.85434 16.85434 11.64049 190s [281] 10.79647 10.79647 10.79647 16.85434 10.79647 13.94088 13.94088 10.79647 190s [289] 11.64049 16.85434 10.79647 16.85434 18.01923 11.64049 18.01923 17.60229 190s [297] 11.64049 10.96962 18.01923 18.01923 10.79647 16.85434 17.60229 18.01923 190s [305] 10.79647 16.85434 16.85434 17.60229 10.79647 11.64049 16.85434 17.60229 190s [313] 17.60229 13.94088 11.64049 17.60229 13.94088 18.01923 16.85434 11.64049 190s [321] 13.94088 11.64049 18.01923 16.85434 16.85434 18.01923 13.94088 16.85434 190s [329] 17.60229 11.64049 11.64049 17.60229 17.60229 18.01923 11.64049 13.94088 190s [337] 13.94088 16.85434 16.85434 10.79647 13.94088 17.60229 11.64049 13.94088 190s [345] 16.85434 18.01923 13.94088 13.94088 10.96962 16.85434 18.01923 18.01923 190s [353] 13.94088 16.85434 13.94088 16.85434 13.94088 16.85434 13.94088 18.01923 190s [361] 11.64049 13.94088 17.60229 11.64049 13.94088 10.96962 17.60229 13.94088 190s [369] 17.60229 18.01923 13.94088 17.60229 17.60229 13.94088 10.79647 11.64049 190s [377] 11.64049 17.60229 10.79647 18.01923 11.64049 11.64049 16.85434 13.94088 190s [385] 11.64049 18.01923 13.94088 18.01923 17.60229 13.94088 13.94088 17.60229 190s [393] 16.85434 13.94088 17.60229 10.79647 17.60229 11.64049 10.79647 13.94088 190s [401] 17.60229 11.64049 16.85434 16.85434 10.96962 16.85434 11.64049 13.94088 190s [409] 11.64049 13.94088 13.94088 17.60229 11.64049 17.60229 18.01923 10.79647 190s [417] 17.60229 11.64049 10.79647 18.01923 17.60229 13.94088 13.94088 17.60229 190s [425] 17.60229 16.85434 16.85434 16.85434 18.01923 10.96962 18.01923 17.60229 190s [433] 10.79647 13.94088 18.01923 17.60229 17.60229 11.64049 10.79647 13.94088 190s [441] 18.01923 17.60229 16.85434 13.94088 16.85434 18.01923 16.85434 18.01923 190s [449] 10.79647 18.01923 18.01923 11.64049 16.85434 17.60229 10.79647 11.64049 190s [457] 16.85434 10.96962 13.94088 18.01923 18.01923 16.85434 16.85434 13.94088 190s [465] 10.96962 18.01923 17.60229 11.64049 10.79647 11.64049 17.60229 17.60229 190s [473] 18.01923 16.85434 18.01923 11.64049 13.94088 18.01923 18.01923 10.96962 190s [481] 13.94088 18.01923 18.01923 13.94088 17.60229 10.79647 18.01923 16.85434 190s [489] 11.64049 13.94088 18.01923 18.01923 16.85434 13.94088 18.01923 16.85434 190s [497] 10.79647 11.64049 16.85434 17.60229 13.94088 16.85434 10.79647 18.01923 190s [505] 13.94088 10.79647 11.64049 18.01923 17.60229 17.60229 13.94088 17.60229 190s [513] 10.96962 10.79647 13.94088 13.94088 13.94088 17.60229 17.60229 10.79647 190s [521] 17.60229 17.60229 13.94088 18.01923 13.94088 11.64049 11.64049 18.01923 190s [529] 16.85434 16.85434 13.94088 17.60229 18.01923 16.85434 17.60229 13.94088 190s [537] 13.94088 13.94088 18.01923 10.79647 10.79647 17.60229 13.94088 10.96962 190s [545] 10.79647 16.85434 18.01923 16.85434 16.85434 18.01923 16.85434 16.85434 190s [553] 17.60229 10.79647 10.79647 13.94088 16.85434 18.01923 18.01923 13.94088 190s [561] 13.94088 17.60229 18.01923 17.60229 17.60229 10.79647 17.60229 13.94088 190s [569] 18.01923 11.64049 10.79647 13.94088 11.64049 17.60229 18.01923 13.94088 190s [577] 16.85434 11.64049 17.60229 13.94088 10.79647 18.01923 17.60229 11.64049 190s [585] 16.85434 13.94088 17.60229 11.64049 16.85434 190s 190s $se.fit 190s [1] 0.4716508 0.3621952 0.5408090 0.4716508 0.4610877 0.3621952 0.5408090 190s [8] 0.4610877 0.4716508 0.5653200 0.4716508 0.4716508 0.5408090 0.4610877 190s [15] 0.3763389 0.5653200 0.4716508 0.4610877 0.4610877 0.5653200 0.5408090 190s [22] 0.5653200 0.5408090 0.3621952 0.3621952 0.4610877 0.3621952 0.3621952 190s [29] 0.4610877 0.4716508 0.5408090 0.3621952 0.4610877 0.4610877 0.4610877 190s [36] 0.5653200 0.5653200 0.4610877 0.3621952 0.4610877 0.4610877 0.3763389 190s [43] 0.4610877 0.4716508 0.4610877 0.4716508 0.3763389 0.5408090 0.3763389 190s [50] 0.3763389 0.5653200 0.5408090 0.3621952 0.3621952 0.5408090 0.4610877 190s [57] 0.5408090 0.3621952 0.3763389 0.3763389 0.4610877 0.5653200 0.5408090 190s [64] 0.3621952 0.3621952 0.3621952 0.5653200 0.5408090 0.4610877 0.4716508 190s [71] 0.5653200 0.3763389 0.3763389 0.3621952 0.4610877 0.4610877 0.4716508 190s [78] 0.5653200 0.4716508 0.3621952 0.3621952 0.4610877 0.4610877 0.4610877 190s [85] 0.4610877 0.5408090 0.3621952 0.3763389 0.5653200 0.3763389 0.5408090 190s [92] 0.3621952 0.4610877 0.5408090 0.4716508 0.3621952 0.4716508 0.3621952 190s [99] 0.3621952 0.3621952 0.4610877 0.4716508 0.3621952 0.5653200 0.4716508 190s [106] 0.3621952 0.5653200 0.3621952 0.4610877 0.4610877 0.3763389 0.3621952 190s [113] 0.4716508 0.4610877 0.4616804 0.4716508 0.4716508 0.5653200 0.3621952 190s [120] 0.5653200 0.5653200 0.3621952 0.4616804 0.3763389 0.5653200 0.4716508 190s [127] 0.3621952 0.4610877 0.4716508 0.3763389 0.3621952 0.3763389 0.5408090 190s [134] 0.3621952 0.4610877 0.4716508 0.3621952 0.5408090 0.3621952 0.4616804 190s [141] 0.3621952 0.3621952 0.3763389 0.3621952 0.4716508 0.5408090 0.3621952 190s [148] 0.4610877 0.4610877 0.5653200 0.4716508 0.4610877 0.5653200 0.4610877 190s [155] 0.3621952 0.5408090 0.3621952 0.5653200 0.5653200 0.3763389 0.4610877 190s [162] 0.5653200 0.4616804 0.4610877 0.4610877 0.4716508 0.5653200 0.3763389 190s [169] 0.5653200 0.4610877 0.4610877 0.4716508 0.4716508 0.5653200 0.5408090 190s [176] 0.3763389 0.5653200 0.4716508 0.5653200 0.5408090 0.5653200 0.4610877 190s [183] 0.4716508 0.4716508 0.4610877 0.4610877 0.4616804 0.5408090 0.4610877 190s [190] 0.3763389 0.5408090 0.5408090 0.3763389 0.5653200 0.5408090 0.4610877 190s [197] 0.5408090 0.5408090 0.4616804 0.4610877 0.5653200 0.5408090 0.4610877 190s [204] 0.3621952 0.3621952 0.5408090 0.3621952 0.5408090 0.3763389 0.4716508 190s [211] 0.4610877 0.4610877 0.4610877 0.5653200 0.5653200 0.4716508 0.4716508 190s [218] 0.4610877 0.4610877 0.4616804 0.5408090 0.5408090 0.5653200 0.3763389 190s [225] 0.5408090 0.3763389 0.4610877 0.3763389 0.5653200 0.5408090 0.4610877 190s [232] 0.3621952 0.3621952 0.4610877 0.3763389 0.4716508 0.3763389 0.5653200 190s [239] 0.5653200 0.3621952 0.5408090 0.3621952 0.4716508 0.4610877 0.5408090 190s [246] 0.3621952 0.4610877 0.5408090 0.3763389 0.3763389 0.5408090 0.4716508 190s [253] 0.4616804 0.5408090 0.3621952 0.3621952 0.5408090 0.3621952 0.4716508 190s [260] 0.3621952 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.3763389 190s [267] 0.3621952 0.4610877 0.4610877 0.3763389 0.4610877 0.3763389 0.5653200 190s [274] 0.4610877 0.3763389 0.3763389 0.4616804 0.4716508 0.4716508 0.3763389 190s [281] 0.5653200 0.5653200 0.5653200 0.4716508 0.5653200 0.4610877 0.4610877 190s [288] 0.5653200 0.3763389 0.4716508 0.5653200 0.4716508 0.5408090 0.3763389 190s [295] 0.5408090 0.3621952 0.3763389 0.4616804 0.5408090 0.5408090 0.5653200 190s [302] 0.4716508 0.3621952 0.5408090 0.5653200 0.4716508 0.4716508 0.3621952 190s [309] 0.5653200 0.3763389 0.4716508 0.3621952 0.3621952 0.4610877 0.3763389 190s [316] 0.3621952 0.4610877 0.5408090 0.4716508 0.3763389 0.4610877 0.3763389 190s [323] 0.5408090 0.4716508 0.4716508 0.5408090 0.4610877 0.4716508 0.3621952 190s [330] 0.3763389 0.3763389 0.3621952 0.3621952 0.5408090 0.3763389 0.4610877 190s [337] 0.4610877 0.4716508 0.4716508 0.5653200 0.4610877 0.3621952 0.3763389 190s [344] 0.4610877 0.4716508 0.5408090 0.4610877 0.4610877 0.4616804 0.4716508 190s [351] 0.5408090 0.5408090 0.4610877 0.4716508 0.4610877 0.4716508 0.4610877 190s [358] 0.4716508 0.4610877 0.5408090 0.3763389 0.4610877 0.3621952 0.3763389 190s [365] 0.4610877 0.4616804 0.3621952 0.4610877 0.3621952 0.5408090 0.4610877 190s [372] 0.3621952 0.3621952 0.4610877 0.5653200 0.3763389 0.3763389 0.3621952 190s [379] 0.5653200 0.5408090 0.3763389 0.3763389 0.4716508 0.4610877 0.3763389 190s [386] 0.5408090 0.4610877 0.5408090 0.3621952 0.4610877 0.4610877 0.3621952 190s [393] 0.4716508 0.4610877 0.3621952 0.5653200 0.3621952 0.3763389 0.5653200 190s [400] 0.4610877 0.3621952 0.3763389 0.4716508 0.4716508 0.4616804 0.4716508 190s [407] 0.3763389 0.4610877 0.3763389 0.4610877 0.4610877 0.3621952 0.3763389 190s [414] 0.3621952 0.5408090 0.5653200 0.3621952 0.3763389 0.5653200 0.5408090 190s [421] 0.3621952 0.4610877 0.4610877 0.3621952 0.3621952 0.4716508 0.4716508 190s [428] 0.4716508 0.5408090 0.4616804 0.5408090 0.3621952 0.5653200 0.4610877 190s [435] 0.5408090 0.3621952 0.3621952 0.3763389 0.5653200 0.4610877 0.5408090 190s [442] 0.3621952 0.4716508 0.4610877 0.4716508 0.5408090 0.4716508 0.5408090 190s [449] 0.5653200 0.5408090 0.5408090 0.3763389 0.4716508 0.3621952 0.5653200 190s [456] 0.3763389 0.4716508 0.4616804 0.4610877 0.5408090 0.5408090 0.4716508 190s [463] 0.4716508 0.4610877 0.4616804 0.5408090 0.3621952 0.3763389 0.5653200 190s [470] 0.3763389 0.3621952 0.3621952 0.5408090 0.4716508 0.5408090 0.3763389 190s [477] 0.4610877 0.5408090 0.5408090 0.4616804 0.4610877 0.5408090 0.5408090 190s [484] 0.4610877 0.3621952 0.5653200 0.5408090 0.4716508 0.3763389 0.4610877 190s [491] 0.5408090 0.5408090 0.4716508 0.4610877 0.5408090 0.4716508 0.5653200 190s [498] 0.3763389 0.4716508 0.3621952 0.4610877 0.4716508 0.5653200 0.5408090 190s [505] 0.4610877 0.5653200 0.3763389 0.5408090 0.3621952 0.3621952 0.4610877 190s [512] 0.3621952 0.4616804 0.5653200 0.4610877 0.4610877 0.4610877 0.3621952 190s [519] 0.3621952 0.5653200 0.3621952 0.3621952 0.4610877 0.5408090 0.4610877 190s [526] 0.3763389 0.3763389 0.5408090 0.4716508 0.4716508 0.4610877 0.3621952 190s [533] 0.5408090 0.4716508 0.3621952 0.4610877 0.4610877 0.4610877 0.5408090 190s [540] 0.5653200 0.5653200 0.3621952 0.4610877 0.4616804 0.5653200 0.4716508 190s [547] 0.5408090 0.4716508 0.4716508 0.5408090 0.4716508 0.4716508 0.3621952 190s [554] 0.5653200 0.5653200 0.4610877 0.4716508 0.5408090 0.5408090 0.4610877 190s [561] 0.4610877 0.3621952 0.5408090 0.3621952 0.3621952 0.5653200 0.3621952 190s [568] 0.4610877 0.5408090 0.3763389 0.5653200 0.4610877 0.3763389 0.3621952 190s [575] 0.5408090 0.4610877 0.4716508 0.3763389 0.3621952 0.4610877 0.5653200 190s [582] 0.5408090 0.3621952 0.3763389 0.4716508 0.4610877 0.3621952 0.3763389 190s [589] 0.4716508 190s 190s [1] 64.48518 190s [1] 3722.867 190s [1] 3722.867 190s Dose Response Model 190s 190s Model: betaMod 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -23.081 -4.023 0.069 3.767 16.317 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 1.02e+01 0.82024 190s eMax 7.36e+00 0.69530 190s delta1 2.25e+00 0.60058 190s delta2 1.01e+00 0.33271 190s age 5.72e-04 0.00829 190s centergreen 7.41e-01 0.73739 190s centerred 8.30e-01 0.74509 190s centersilver 7.30e-01 0.70097 190s centeryellow 6.56e-01 0.73274 190s 190s Residual standard error: 5.65 190s Degrees of freedom: 580 190s 190s Formula: y ~ cbind(XX, betaMod(x, 0, 1, delta1, delta2, scl)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s delta1 2.253e+00 6.006e-01 3.751 0.000194 *** 190s delta2 1.006e+00 3.327e-01 3.025 0.002600 ** 190s .lin.(Intercept) 1.023e+01 8.202e-01 12.470 < 2e-16 *** 190s .lin.centergreen 7.409e-01 7.374e-01 1.005 0.315410 190s .lin.centerred 8.298e-01 7.451e-01 1.114 0.265866 190s .lin.centersilver 7.301e-01 7.010e-01 1.042 0.298051 190s .lin.centeryellow 6.562e-01 7.327e-01 0.896 0.370886 190s .lin.age 5.723e-04 8.288e-03 0.069 0.944970 190s .lin7 7.357e+00 6.953e-01 10.581 < 2e-16 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 5.653 on 580 degrees of freedom 190s 190s Number of iterations to convergence: 6 190s Achieved convergence tolerance: 9.472e-06 190s 190s e0 eMax delta1 delta2 190s e0 0.672788555 -0.2729452009 2.029556e-01 8.893435e-02 190s eMax -0.272945201 0.4834404097 -4.411253e-02 1.212204e-02 190s delta1 0.202955602 -0.0441125316 3.606932e-01 1.869163e-01 190s delta2 0.088934352 0.0121220371 1.869163e-01 1.106931e-01 190s age -0.003530727 0.0001030079 4.984077e-05 7.767012e-05 190s centergreen -0.234450342 -0.0348602441 1.207912e-02 1.405608e-03 190s centerred -0.253662862 -0.0121021695 6.628052e-04 -2.474391e-03 190s centersilver -0.222055302 -0.0379891034 1.347032e-02 4.810797e-03 190s centeryellow -0.242096858 -0.0036488338 1.244170e-02 2.099443e-03 190s age centergreen centerred centersilver 190s e0 -3.530727e-03 -0.2344503416 -0.2536628616 -2.220553e-01 190s eMax 1.030079e-04 -0.0348602441 -0.0121021695 -3.798910e-02 190s delta1 4.984077e-05 0.0120791216 0.0006628052 1.347032e-02 190s delta2 7.767012e-05 0.0014056079 -0.0024743906 4.810797e-03 190s age 6.868689e-05 0.0001513555 0.0001912581 -2.484136e-05 190s centergreen 1.513555e-04 0.5437481113 0.2513884520 2.524566e-01 190s centerred 1.912581e-04 0.2513884520 0.5551521388 2.504165e-01 190s centersilver -2.484136e-05 0.2524565639 0.2504164883 4.913597e-01 190s centeryellow -1.767809e-05 0.2510775793 0.2504115027 2.500668e-01 190s centeryellow 190s e0 -2.420969e-01 190s eMax -3.648834e-03 190s delta1 1.244170e-02 190s delta2 2.099443e-03 190s age -1.767809e-05 190s centergreen 2.510776e-01 190s centerred 2.504115e-01 190s centersilver 2.500668e-01 190s centeryellow 5.369021e-01 190s delta1 delta2 .lin.(Intercept) .lin.centergreen 190s delta1 3.606961e-01 1.869176e-01 0.202956171 0.0120792615 190s delta2 1.869176e-01 1.106938e-01 0.088934648 0.0014056742 190s .lin.(Intercept) 2.029562e-01 8.893465e-02 0.672787602 -0.2344503743 190s .lin.centergreen 1.207926e-02 1.405674e-03 -0.234450374 0.5437481112 190s .lin.centerred 6.627065e-04 -2.474441e-03 -0.253662951 0.2513884457 190s .lin.centersilver 1.347037e-02 4.810825e-03 -0.222055391 0.2524565593 190s .lin.centeryellow 1.244156e-02 2.099363e-03 -0.242097015 0.2510775716 190s .lin.age 4.984142e-05 7.767047e-05 -0.003530726 0.0001513556 190s .lin7 -4.411231e-02 1.212224e-02 -0.272944309 -0.0348602205 190s .lin.centerred .lin.centersilver .lin.centeryellow 190s delta1 0.0006627065 1.347037e-02 1.244156e-02 190s delta2 -0.0024744413 4.810825e-03 2.099363e-03 190s .lin.(Intercept) -0.2536629506 -2.220554e-01 -2.420970e-01 190s .lin.centergreen 0.2513884457 2.524566e-01 2.510776e-01 190s .lin.centerred 0.5551521364 2.504165e-01 2.504115e-01 190s .lin.centersilver 0.2504164813 4.913597e-01 2.500668e-01 190s .lin.centeryellow 0.2504114958 2.500668e-01 5.369021e-01 190s .lin.age 0.0001912581 -2.484131e-05 -1.767806e-05 190s .lin7 -0.0121021533 -3.798904e-02 -3.648777e-03 190s .lin.age .lin7 190s delta1 4.984142e-05 -0.0441123055 190s delta2 7.767047e-05 0.0121222432 190s .lin.(Intercept) -3.530726e-03 -0.2729443093 190s .lin.centergreen 1.513556e-04 -0.0348602205 190s .lin.centerred 1.912581e-04 -0.0121021533 190s .lin.centersilver -2.484131e-05 -0.0379890373 190s .lin.centeryellow -1.767806e-05 -0.0036487770 190s .lin.age 6.868689e-05 0.0001030081 190s .lin7 1.030081e-04 0.4834404337 190s $fit 190s [1] 0.000000 2.289162 190s 190s $se.fit 190s [1] 0.0000000 0.7519464 190s 190s $fit 190s [1] 10.91275 13.20191 190s 190s $se.fit 190s [1] 0.7364602 0.6423551 190s 190s [1] 65.39866 190s [1] -485.5937 190s [1] -485.5937 190s Dose Response Model 190s 190s Model: emax 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -0.0666 -0.0180 -0.0011 0.0193 0.0692 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -0.5830 6.00e-03 190s eMax 0.0163 3.36e-02 190s ed50 286.5994 1.91e+03 190s 190s Residual standard error: 0.0281 190s Degrees of freedom: 111 190s 190s Formula: y ~ emax(x, e0, emax, ed50) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s e0 -0.58297 0.00600 -97.164 <2e-16 *** 190s emax 0.01632 0.03356 0.486 0.628 190s ed50 286.45918 1905.11276 0.150 0.881 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.02814 on 111 degrees of freedom 190s 190s Number of iterations to convergence: 8 190s Achieved convergence tolerance: 9.607e-06 190s 190s e0 eMax ed50 190s e0 3.599786e-05 -2.913476e-05 1.313843e+00 190s eMax -2.913476e-05 1.126946e-03 6.130311e+01 190s ed50 1.313843e+00 6.130311e+01 3.631673e+06 190s e0 emax ed50 190s e0 3.599786e-05 -2.914142e-05 1.313001e+00 190s emax -2.914142e-05 1.126323e-03 6.126673e+01 190s ed50 1.313001e+00 6.126673e+01 3.629455e+06 190s $fit 190s [1] 0.01155472 0.01155472 0.00000000 0.01155472 0.01155472 0.01155472 190s [7] 0.01056820 0.01056820 0.01056820 0.01155472 0.01239306 0.01056820 190s [13] 0.00000000 0.01239306 0.01155472 0.01056820 0.01056820 0.00000000 190s [19] 0.01155472 0.01212084 0.01212084 0.01056820 0.00000000 0.01155472 190s [25] 0.01056820 0.01056820 0.01155472 0.00000000 0.00000000 0.01155472 190s [31] 0.01056820 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 190s [37] 0.01155472 0.01212084 0.00000000 0.01155472 0.01239306 0.01155472 190s [43] 0.01056820 0.01056820 0.01155472 0.01155472 0.01155472 0.00000000 190s [49] 0.01155472 0.01056820 0.01056820 0.00000000 0.01056820 0.01239306 190s [55] 0.00000000 0.01056820 0.01155472 0.01056820 0.01239306 0.01239306 190s [61] 0.01056820 0.01239306 0.01056820 0.01155472 0.01212084 0.01155472 190s [67] 0.01056820 0.01056820 0.01239306 0.01056820 0.00000000 0.01155472 190s [73] 0.01239306 0.01155472 0.01155472 0.01056820 0.00000000 0.00000000 190s [79] 0.01155472 0.00000000 0.00000000 0.00000000 0.01155472 0.01155472 190s [85] 0.01056820 0.01056820 0.01155472 0.01056820 0.01155472 0.01155472 190s [91] 0.01212084 0.01155472 0.01212084 0.01056820 0.00000000 0.01155472 190s [97] 0.01155472 0.01056820 0.01155472 0.00000000 0.01155472 0.01155472 190s [103] 0.01056820 0.01056820 0.01056820 0.00000000 0.01155472 0.00000000 190s [109] 0.01056820 0.01056820 0.01155472 0.01056820 0.00000000 0.01056820 190s 190s $se.fit 190s [1] 0.006800657 0.006800657 0.000000000 0.006800657 0.006800657 0.006800657 190s [7] 0.007368990 0.007368990 0.007368990 0.006800657 0.008598392 0.007368990 190s [13] 0.000000000 0.008598392 0.006800657 0.007368990 0.007368990 0.000000000 190s [19] 0.006800657 0.007779856 0.007779856 0.007368990 0.000000000 0.006800657 190s [25] 0.007368990 0.007368990 0.006800657 0.000000000 0.000000000 0.006800657 190s [31] 0.007368990 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 190s [37] 0.006800657 0.007779856 0.000000000 0.006800657 0.008598392 0.006800657 190s [43] 0.007368990 0.007368990 0.006800657 0.006800657 0.006800657 0.000000000 190s [49] 0.006800657 0.007368990 0.007368990 0.000000000 0.007368990 0.008598392 190s [55] 0.000000000 0.007368990 0.006800657 0.007368990 0.008598392 0.008598392 190s [61] 0.007368990 0.008598392 0.007368990 0.006800657 0.007779856 0.006800657 190s [67] 0.007368990 0.007368990 0.008598392 0.007368990 0.000000000 0.006800657 190s [73] 0.008598392 0.006800657 0.006800657 0.007368990 0.000000000 0.000000000 190s [79] 0.006800657 0.000000000 0.000000000 0.000000000 0.006800657 0.006800657 190s [85] 0.007368990 0.007368990 0.006800657 0.007368990 0.006800657 0.006800657 190s [91] 0.007779856 0.006800657 0.007779856 0.007368990 0.000000000 0.006800657 190s [97] 0.006800657 0.007368990 0.006800657 0.000000000 0.006800657 0.006800657 190s [103] 0.007368990 0.007368990 0.007368990 0.000000000 0.006800657 0.000000000 190s [109] 0.007368990 0.007368990 0.006800657 0.007368990 0.000000000 0.007368990 190s 190s $fit 190s [1] -0.5714146 -0.5714146 -0.5829694 -0.5714146 -0.5714146 -0.5714146 190s [7] -0.5724012 -0.5724012 -0.5724012 -0.5714146 -0.5705763 -0.5724012 190s [13] -0.5829694 -0.5705763 -0.5714146 -0.5724012 -0.5724012 -0.5829694 190s [19] -0.5714146 -0.5708485 -0.5708485 -0.5724012 -0.5829694 -0.5714146 190s [25] -0.5724012 -0.5724012 -0.5714146 -0.5829694 -0.5829694 -0.5714146 190s [31] -0.5724012 -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 190s [37] -0.5714146 -0.5708485 -0.5829694 -0.5714146 -0.5705763 -0.5714146 190s [43] -0.5724012 -0.5724012 -0.5714146 -0.5714146 -0.5714146 -0.5829694 190s [49] -0.5714146 -0.5724012 -0.5724012 -0.5829694 -0.5724012 -0.5705763 190s [55] -0.5829694 -0.5724012 -0.5714146 -0.5724012 -0.5705763 -0.5705763 190s [61] -0.5724012 -0.5705763 -0.5724012 -0.5714146 -0.5708485 -0.5714146 190s [67] -0.5724012 -0.5724012 -0.5705763 -0.5724012 -0.5829694 -0.5714146 190s [73] -0.5705763 -0.5714146 -0.5714146 -0.5724012 -0.5829694 -0.5829694 190s [79] -0.5714146 -0.5829694 -0.5829694 -0.5829694 -0.5714146 -0.5714146 190s [85] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5714146 -0.5714146 190s [91] -0.5708485 -0.5714146 -0.5708485 -0.5724012 -0.5829694 -0.5714146 190s [97] -0.5714146 -0.5724012 -0.5714146 -0.5829694 -0.5714146 -0.5714146 190s [103] -0.5724012 -0.5724012 -0.5724012 -0.5829694 -0.5714146 -0.5829694 190s [109] -0.5724012 -0.5724012 -0.5714146 -0.5724012 -0.5829694 -0.5724012 190s 190s $se.fit 190s [1] 0.003169353 0.003169353 0.005999821 0.003169353 0.003169353 0.003169353 190s [7] 0.004290400 0.004290400 0.004290400 0.003169353 0.006190654 0.004290400 190s [13] 0.005999821 0.006190654 0.003169353 0.004290400 0.004290400 0.005999821 190s [19] 0.003169353 0.004963663 0.004963663 0.004290400 0.005999821 0.003169353 190s [25] 0.004290400 0.004290400 0.003169353 0.005999821 0.005999821 0.003169353 190s [31] 0.004290400 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 190s [37] 0.003169353 0.004963663 0.005999821 0.003169353 0.006190654 0.003169353 190s [43] 0.004290400 0.004290400 0.003169353 0.003169353 0.003169353 0.005999821 190s [49] 0.003169353 0.004290400 0.004290400 0.005999821 0.004290400 0.006190654 190s [55] 0.005999821 0.004290400 0.003169353 0.004290400 0.006190654 0.006190654 190s [61] 0.004290400 0.006190654 0.004290400 0.003169353 0.004963663 0.003169353 190s [67] 0.004290400 0.004290400 0.006190654 0.004290400 0.005999821 0.003169353 190s [73] 0.006190654 0.003169353 0.003169353 0.004290400 0.005999821 0.005999821 190s [79] 0.003169353 0.005999821 0.005999821 0.005999821 0.003169353 0.003169353 190s [85] 0.004290400 0.004290400 0.003169353 0.004290400 0.003169353 0.003169353 190s [91] 0.004963663 0.003169353 0.004963663 0.004290400 0.005999821 0.003169353 190s [97] 0.003169353 0.004290400 0.003169353 0.005999821 0.003169353 0.003169353 190s [103] 0.004290400 0.004290400 0.004290400 0.005999821 0.003169353 0.005999821 190s [109] 0.004290400 0.004290400 0.003169353 0.004290400 0.005999821 0.004290400 190s 190s [1] 126.5178 190s [1] -481.376 190s [1] -481.378 190s Dose Response Model 190s 190s Model: emax 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -0.07408 -0.01641 -0.00232 0.01807 0.07476 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -5.81e-01 8.97e-03 190s eMax 2.93e-02 9.13e-02 190s ed50 9.03e+02 5.00e+03 190s age -1.22e-04 1.06e-04 190s centergreen 1.07e-02 8.31e-03 190s centerred 9.27e-03 7.73e-03 190s centersilver 1.22e-03 8.91e-03 190s centeryellow -4.65e-03 8.50e-03 190s 190s Residual standard error: 0.0281 190s Degrees of freedom: 106 190s 190s Formula: y ~ cbind(XX, emax(x, 0, 1, ed50)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s ed50 1.111e+03 6.451e+03 0.172 0.864 190s .lin.(Intercept) -5.813e-01 8.970e-03 -64.810 <2e-16 *** 190s .lin.centergreen 1.071e-02 8.309e-03 1.288 0.200 190s .lin.centerred 9.301e-03 7.726e-03 1.204 0.231 190s .lin.centersilver 1.196e-03 8.915e-03 0.134 0.894 190s .lin.centeryellow -4.665e-03 8.497e-03 -0.549 0.584 190s .lin.age -1.213e-04 1.057e-04 -1.148 0.254 190s .lin7 3.300e-02 1.170e-01 0.282 0.778 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.02808 on 106 degrees of freedom 190s 190s Number of iterations to convergence: 9 190s Achieved convergence tolerance: 7.028e-06 190s 190s e0 eMax ed50 age 190s e0 8.046543e-05 -3.844545e-05 2.355425e+00 -4.980066e-07 190s eMax -3.844545e-05 8.342573e-03 4.493061e+02 1.107091e-06 190s ed50 2.355425e+00 4.493061e+02 2.497229e+07 6.444381e-02 190s age -4.980066e-07 1.107091e-06 6.444381e-02 1.116195e-08 190s centergreen -1.978501e-05 6.446464e-05 4.524614e+00 -8.645567e-08 190s centerred -3.432079e-05 7.922237e-05 3.670388e+00 1.157010e-08 190s centersilver -1.753629e-05 -7.656779e-05 -3.796015e+00 -2.309374e-07 190s centeryellow -3.332560e-05 -5.044361e-05 -2.141277e+00 1.346886e-07 190s centergreen centerred centersilver centeryellow 190s e0 -1.978501e-05 -3.432079e-05 -1.753629e-05 -3.332560e-05 190s eMax 6.446464e-05 7.922237e-05 -7.656779e-05 -5.044361e-05 190s ed50 4.524614e+00 3.670388e+00 -3.796015e+00 -2.141277e+00 190s age -8.645567e-08 1.157010e-08 -2.309374e-07 1.346886e-07 190s centergreen 6.902160e-05 3.007695e-05 3.223410e-05 2.943878e-05 190s centerred 3.007695e-05 5.968790e-05 2.924362e-05 2.945739e-05 190s centersilver 3.223410e-05 2.924362e-05 7.947639e-05 2.823145e-05 190s centeryellow 2.943878e-05 2.945739e-05 2.823145e-05 7.219729e-05 190s ed50 .lin.(Intercept) .lin.centergreen 190s ed50 4.162109e+07 3.618133e+00 6.072527e+00 190s .lin.(Intercept) 3.618133e+00 8.045192e-05 -1.978784e-05 190s .lin.centergreen 6.072527e+00 -1.978784e-05 6.904772e-05 190s .lin.centerred 4.627132e+00 -3.432899e-05 3.008663e-05 190s .lin.centersilver -4.847154e+00 -1.752828e-05 3.222029e-05 190s .lin.centeryellow -2.727240e+00 -3.332482e-05 2.942341e-05 190s .lin.age 8.505295e-02 -4.980346e-07 -8.605363e-08 190s .lin7 7.456212e+02 -2.614221e-05 9.001668e-05 190s .lin.centerred .lin.centersilver .lin.centeryellow 190s ed50 4.627132e+00 -4.847154e+00 -2.727240e+00 190s .lin.(Intercept) -3.432899e-05 -1.752828e-05 -3.332482e-05 190s .lin.centergreen 3.008663e-05 3.222029e-05 2.942341e-05 190s .lin.centerred 5.968601e-05 2.924192e-05 2.945040e-05 190s .lin.centersilver 2.924192e-05 7.947836e-05 2.823890e-05 190s .lin.centeryellow 2.945040e-05 2.823890e-05 7.220391e-05 190s .lin.age 1.172543e-08 -2.311322e-07 1.344697e-07 190s .lin7 9.802604e-05 -9.643580e-05 -6.245218e-05 190s .lin.age .lin7 190s ed50 8.505295e-02 7.456212e+02 190s .lin.(Intercept) -4.980346e-07 -2.614221e-05 190s .lin.centergreen -8.605363e-08 9.001668e-05 190s .lin.centerred 1.172543e-08 9.802604e-05 190s .lin.centersilver -2.311322e-07 -9.643580e-05 190s .lin.centeryellow 1.344697e-07 -6.245218e-05 190s .lin.age 1.116761e-08 1.469361e-06 190s .lin7 1.469361e-06 1.368628e-02 190s $fit 190s [1] 0.000000000 0.002916944 190s 190s $se.fit 190s [1] 0.000000 0.005795 190s 190s $fit 190s [1] -0.5861913 -0.5832744 190s 190s $se.fit 190s [1] 0.008937545 0.009550033 190s 190s [1] 186.1323 190s [1] 2049.321 190s [1] 2049.321 190s Dose Response Model 190s 190s Model: sigEmax 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -13.6383 -2.8339 0.0791 3.0983 10.5294 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -10.92 0.555 190s eMax 17.17 3.430 190s ed50 379.22 148.679 190s h 1.38 0.349 190s 190s Residual standard error: 4.37 190s Degrees of freedom: 349 190s 190s Formula: y ~ sigEmax(x, e0, emax, ed50, h) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s e0 -10.9166 0.5552 -19.664 < 2e-16 *** 190s emax 17.1659 3.4296 5.005 8.87e-07 *** 190s ed50 379.2177 148.6773 2.551 0.0112 * 190s h 1.3754 0.3490 3.941 9.81e-05 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 4.372 on 349 degrees of freedom 190s 190s Number of iterations to convergence: 4 190s Achieved convergence tolerance: 7.009e-07 190s 190s e0 eMax ed50 h 190s e0 0.30821303 -0.518459 6.111486 0.06026433 190s eMax -0.51845900 11.762553 468.796873 -1.10430569 190s ed50 6.11148634 468.796873 22105.397044 -40.29692787 190s h 0.06026433 -1.104306 -40.296928 0.12181039 190s e0 emax ed50 h 190s e0 0.30821303 -0.5184566 6.111568 0.06026447 190s emax -0.51845655 11.7623435 468.787156 -1.10429851 190s ed50 6.11156813 468.7871558 22104.941251 -40.29652562 190s h 0.06026447 -1.1042985 -40.296526 0.12181099 190s $fit 190s [1] 12.497935 12.497935 13.842361 2.869998 13.842361 13.842361 0.000000 190s [8] 0.000000 13.842361 2.869998 12.497935 12.497935 11.114421 12.497935 190s [15] 12.497935 12.497935 12.497935 12.497935 0.000000 12.497935 12.497935 190s [22] 0.000000 13.842361 13.842361 0.000000 0.000000 2.869998 12.497935 190s [29] 2.869998 2.869998 13.842361 0.000000 11.114421 12.497935 0.000000 190s [36] 13.842361 13.842361 12.497935 13.842361 2.869998 12.497935 12.497935 190s [43] 12.497935 2.869998 12.497935 12.497935 11.114421 12.497935 13.842361 190s [50] 13.842361 12.497935 0.000000 12.497935 12.497935 0.000000 12.497935 190s [57] 0.000000 13.842361 12.497935 2.869998 12.497935 13.842361 12.497935 190s [64] 13.842361 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 190s [71] 12.497935 2.869998 12.497935 12.497935 0.000000 13.842361 0.000000 190s [78] 13.842361 12.497935 12.497935 12.497935 12.497935 13.842361 2.869998 190s [85] 12.497935 12.497935 12.497935 0.000000 0.000000 0.000000 0.000000 190s [92] 2.869998 12.497935 12.497935 2.869998 12.497935 12.497935 2.869998 190s [99] 12.497935 0.000000 12.497935 0.000000 2.869998 2.869998 2.869998 190s [106] 12.497935 13.842361 12.497935 2.869998 0.000000 13.842361 2.869998 190s [113] 12.497935 0.000000 12.497935 0.000000 13.842361 12.497935 0.000000 190s [120] 12.497935 11.114421 13.842361 12.497935 12.497935 0.000000 12.497935 190s [127] 2.869998 13.842361 12.497935 13.842361 12.497935 2.869998 12.497935 190s [134] 12.497935 12.497935 12.497935 12.497935 13.842361 13.842361 0.000000 190s [141] 11.114421 12.497935 0.000000 12.497935 13.842361 12.497935 11.114421 190s [148] 12.497935 0.000000 0.000000 2.869998 13.842361 0.000000 2.869998 190s [155] 13.842361 2.869998 11.114421 11.114421 12.497935 0.000000 12.497935 190s [162] 12.497935 2.869998 2.869998 12.497935 12.497935 12.497935 12.497935 190s [169] 2.869998 11.114421 0.000000 13.842361 12.497935 11.114421 12.497935 190s [176] 13.842361 13.842361 12.497935 12.497935 12.497935 12.497935 12.497935 190s [183] 2.869998 13.842361 0.000000 12.497935 12.497935 12.497935 2.869998 190s [190] 13.842361 12.497935 13.842361 2.869998 13.842361 12.497935 12.497935 190s [197] 12.497935 0.000000 11.114421 2.869998 12.497935 2.869998 12.497935 190s [204] 0.000000 12.497935 13.842361 12.497935 13.842361 12.497935 2.869998 190s [211] 2.869998 12.497935 13.842361 13.842361 2.869998 0.000000 13.842361 190s [218] 12.497935 12.497935 0.000000 13.842361 12.497935 12.497935 0.000000 190s [225] 13.842361 11.114421 12.497935 2.869998 12.497935 0.000000 12.497935 190s [232] 12.497935 13.842361 0.000000 12.497935 12.497935 13.842361 0.000000 190s [239] 13.842361 13.842361 12.497935 13.842361 0.000000 2.869998 12.497935 190s [246] 13.842361 12.497935 12.497935 13.842361 2.869998 0.000000 0.000000 190s [253] 11.114421 2.869998 12.497935 2.869998 13.842361 0.000000 12.497935 190s [260] 12.497935 12.497935 12.497935 11.114421 0.000000 0.000000 0.000000 190s [267] 0.000000 0.000000 0.000000 12.497935 13.842361 13.842361 2.869998 190s [274] 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 13.842361 190s [281] 12.497935 12.497935 12.497935 12.497935 2.869998 13.842361 12.497935 190s [288] 11.114421 0.000000 12.497935 12.497935 0.000000 2.869998 12.497935 190s [295] 0.000000 0.000000 13.842361 0.000000 12.497935 13.842361 12.497935 190s [302] 12.497935 13.842361 12.497935 12.497935 2.869998 12.497935 2.869998 190s [309] 11.114421 2.869998 2.869998 0.000000 13.842361 0.000000 12.497935 190s [316] 2.869998 13.842361 0.000000 13.842361 11.114421 12.497935 0.000000 190s [323] 12.497935 12.497935 0.000000 13.842361 13.842361 13.842361 13.842361 190s [330] 11.114421 2.869998 0.000000 12.497935 0.000000 12.497935 13.842361 190s [337] 12.497935 12.497935 12.497935 12.497935 12.497935 13.842361 12.497935 190s [344] 2.869998 13.842361 13.842361 2.869998 11.114421 2.869998 12.497935 190s [351] 12.497935 12.497935 13.842361 190s 190s $se.fit 190s [1] 0.6365415 0.6365415 0.7457881 0.8126372 0.7457881 0.7457881 0.0000000 190s [8] 0.0000000 0.7457881 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 190s [15] 0.6365415 0.6365415 0.6365415 0.6365415 0.0000000 0.6365415 0.6365415 190s [22] 0.0000000 0.7457881 0.7457881 0.0000000 0.0000000 0.8126372 0.6365415 190s [29] 0.8126372 0.8126372 0.7457881 0.0000000 0.8003756 0.6365415 0.0000000 190s [36] 0.7457881 0.7457881 0.6365415 0.7457881 0.8126372 0.6365415 0.6365415 190s [43] 0.6365415 0.8126372 0.6365415 0.6365415 0.8003756 0.6365415 0.7457881 190s [50] 0.7457881 0.6365415 0.0000000 0.6365415 0.6365415 0.0000000 0.6365415 190s [57] 0.0000000 0.7457881 0.6365415 0.8126372 0.6365415 0.7457881 0.6365415 190s [64] 0.7457881 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 190s [71] 0.6365415 0.8126372 0.6365415 0.6365415 0.0000000 0.7457881 0.0000000 190s [78] 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.8126372 190s [85] 0.6365415 0.6365415 0.6365415 0.0000000 0.0000000 0.0000000 0.0000000 190s [92] 0.8126372 0.6365415 0.6365415 0.8126372 0.6365415 0.6365415 0.8126372 190s [99] 0.6365415 0.0000000 0.6365415 0.0000000 0.8126372 0.8126372 0.8126372 190s [106] 0.6365415 0.7457881 0.6365415 0.8126372 0.0000000 0.7457881 0.8126372 190s [113] 0.6365415 0.0000000 0.6365415 0.0000000 0.7457881 0.6365415 0.0000000 190s [120] 0.6365415 0.8003756 0.7457881 0.6365415 0.6365415 0.0000000 0.6365415 190s [127] 0.8126372 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 0.6365415 190s [134] 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.7457881 0.0000000 190s [141] 0.8003756 0.6365415 0.0000000 0.6365415 0.7457881 0.6365415 0.8003756 190s [148] 0.6365415 0.0000000 0.0000000 0.8126372 0.7457881 0.0000000 0.8126372 190s [155] 0.7457881 0.8126372 0.8003756 0.8003756 0.6365415 0.0000000 0.6365415 190s [162] 0.6365415 0.8126372 0.8126372 0.6365415 0.6365415 0.6365415 0.6365415 190s [169] 0.8126372 0.8003756 0.0000000 0.7457881 0.6365415 0.8003756 0.6365415 190s [176] 0.7457881 0.7457881 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 190s [183] 0.8126372 0.7457881 0.0000000 0.6365415 0.6365415 0.6365415 0.8126372 190s [190] 0.7457881 0.6365415 0.7457881 0.8126372 0.7457881 0.6365415 0.6365415 190s [197] 0.6365415 0.0000000 0.8003756 0.8126372 0.6365415 0.8126372 0.6365415 190s [204] 0.0000000 0.6365415 0.7457881 0.6365415 0.7457881 0.6365415 0.8126372 190s [211] 0.8126372 0.6365415 0.7457881 0.7457881 0.8126372 0.0000000 0.7457881 190s [218] 0.6365415 0.6365415 0.0000000 0.7457881 0.6365415 0.6365415 0.0000000 190s [225] 0.7457881 0.8003756 0.6365415 0.8126372 0.6365415 0.0000000 0.6365415 190s [232] 0.6365415 0.7457881 0.0000000 0.6365415 0.6365415 0.7457881 0.0000000 190s [239] 0.7457881 0.7457881 0.6365415 0.7457881 0.0000000 0.8126372 0.6365415 190s [246] 0.7457881 0.6365415 0.6365415 0.7457881 0.8126372 0.0000000 0.0000000 190s [253] 0.8003756 0.8126372 0.6365415 0.8126372 0.7457881 0.0000000 0.6365415 190s [260] 0.6365415 0.6365415 0.6365415 0.8003756 0.0000000 0.0000000 0.0000000 190s [267] 0.0000000 0.0000000 0.0000000 0.6365415 0.7457881 0.7457881 0.8126372 190s [274] 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 0.7457881 190s [281] 0.6365415 0.6365415 0.6365415 0.6365415 0.8126372 0.7457881 0.6365415 190s [288] 0.8003756 0.0000000 0.6365415 0.6365415 0.0000000 0.8126372 0.6365415 190s [295] 0.0000000 0.0000000 0.7457881 0.0000000 0.6365415 0.7457881 0.6365415 190s [302] 0.6365415 0.7457881 0.6365415 0.6365415 0.8126372 0.6365415 0.8126372 190s [309] 0.8003756 0.8126372 0.8126372 0.0000000 0.7457881 0.0000000 0.6365415 190s [316] 0.8126372 0.7457881 0.0000000 0.7457881 0.8003756 0.6365415 0.0000000 190s [323] 0.6365415 0.6365415 0.0000000 0.7457881 0.7457881 0.7457881 0.7457881 190s [330] 0.8003756 0.8126372 0.0000000 0.6365415 0.0000000 0.6365415 0.7457881 190s [337] 0.6365415 0.6365415 0.6365415 0.6365415 0.6365415 0.7457881 0.6365415 190s [344] 0.8126372 0.7457881 0.7457881 0.8126372 0.8003756 0.8126372 0.6365415 190s [351] 0.6365415 0.6365415 0.7457881 190s 190s $fit 190s [1] 1.5813420 1.5813420 2.9257679 -8.0465953 2.9257679 2.9257679 190s [7] -10.9165932 -10.9165932 2.9257679 -8.0465953 1.5813420 1.5813420 190s [13] 0.1978277 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 190s [19] -10.9165932 1.5813420 1.5813420 -10.9165932 2.9257679 2.9257679 190s [25] -10.9165932 -10.9165932 -8.0465953 1.5813420 -8.0465953 -8.0465953 190s [31] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 2.9257679 190s [37] 2.9257679 1.5813420 2.9257679 -8.0465953 1.5813420 1.5813420 190s [43] 1.5813420 -8.0465953 1.5813420 1.5813420 0.1978277 1.5813420 190s [49] 2.9257679 2.9257679 1.5813420 -10.9165932 1.5813420 1.5813420 190s [55] -10.9165932 1.5813420 -10.9165932 2.9257679 1.5813420 -8.0465953 190s [61] 1.5813420 2.9257679 1.5813420 2.9257679 2.9257679 1.5813420 190s [67] 1.5813420 -8.0465953 1.5813420 -8.0465953 1.5813420 -8.0465953 190s [73] 1.5813420 1.5813420 -10.9165932 2.9257679 -10.9165932 2.9257679 190s [79] 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 -8.0465953 190s [85] 1.5813420 1.5813420 1.5813420 -10.9165932 -10.9165932 -10.9165932 190s [91] -10.9165932 -8.0465953 1.5813420 1.5813420 -8.0465953 1.5813420 190s [97] 1.5813420 -8.0465953 1.5813420 -10.9165932 1.5813420 -10.9165932 190s [103] -8.0465953 -8.0465953 -8.0465953 1.5813420 2.9257679 1.5813420 190s [109] -8.0465953 -10.9165932 2.9257679 -8.0465953 1.5813420 -10.9165932 190s [115] 1.5813420 -10.9165932 2.9257679 1.5813420 -10.9165932 1.5813420 190s [121] 0.1978277 2.9257679 1.5813420 1.5813420 -10.9165932 1.5813420 190s [127] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 190s [133] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 190s [139] 2.9257679 -10.9165932 0.1978277 1.5813420 -10.9165932 1.5813420 190s [145] 2.9257679 1.5813420 0.1978277 1.5813420 -10.9165932 -10.9165932 190s [151] -8.0465953 2.9257679 -10.9165932 -8.0465953 2.9257679 -8.0465953 190s [157] 0.1978277 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 190s [163] -8.0465953 -8.0465953 1.5813420 1.5813420 1.5813420 1.5813420 190s [169] -8.0465953 0.1978277 -10.9165932 2.9257679 1.5813420 0.1978277 190s [175] 1.5813420 2.9257679 2.9257679 1.5813420 1.5813420 1.5813420 190s [181] 1.5813420 1.5813420 -8.0465953 2.9257679 -10.9165932 1.5813420 190s [187] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 2.9257679 190s [193] -8.0465953 2.9257679 1.5813420 1.5813420 1.5813420 -10.9165932 190s [199] 0.1978277 -8.0465953 1.5813420 -8.0465953 1.5813420 -10.9165932 190s [205] 1.5813420 2.9257679 1.5813420 2.9257679 1.5813420 -8.0465953 190s [211] -8.0465953 1.5813420 2.9257679 2.9257679 -8.0465953 -10.9165932 190s [217] 2.9257679 1.5813420 1.5813420 -10.9165932 2.9257679 1.5813420 190s [223] 1.5813420 -10.9165932 2.9257679 0.1978277 1.5813420 -8.0465953 190s [229] 1.5813420 -10.9165932 1.5813420 1.5813420 2.9257679 -10.9165932 190s [235] 1.5813420 1.5813420 2.9257679 -10.9165932 2.9257679 2.9257679 190s [241] 1.5813420 2.9257679 -10.9165932 -8.0465953 1.5813420 2.9257679 190s [247] 1.5813420 1.5813420 2.9257679 -8.0465953 -10.9165932 -10.9165932 190s [253] 0.1978277 -8.0465953 1.5813420 -8.0465953 2.9257679 -10.9165932 190s [259] 1.5813420 1.5813420 1.5813420 1.5813420 0.1978277 -10.9165932 190s [265] -10.9165932 -10.9165932 -10.9165932 -10.9165932 -10.9165932 1.5813420 190s [271] 2.9257679 2.9257679 -8.0465953 1.5813420 1.5813420 1.5813420 190s [277] -8.0465953 2.9257679 1.5813420 2.9257679 1.5813420 1.5813420 190s [283] 1.5813420 1.5813420 -8.0465953 2.9257679 1.5813420 0.1978277 190s [289] -10.9165932 1.5813420 1.5813420 -10.9165932 -8.0465953 1.5813420 190s [295] -10.9165932 -10.9165932 2.9257679 -10.9165932 1.5813420 2.9257679 190s [301] 1.5813420 1.5813420 2.9257679 1.5813420 1.5813420 -8.0465953 190s [307] 1.5813420 -8.0465953 0.1978277 -8.0465953 -8.0465953 -10.9165932 190s [313] 2.9257679 -10.9165932 1.5813420 -8.0465953 2.9257679 -10.9165932 190s [319] 2.9257679 0.1978277 1.5813420 -10.9165932 1.5813420 1.5813420 190s [325] -10.9165932 2.9257679 2.9257679 2.9257679 2.9257679 0.1978277 190s [331] -8.0465953 -10.9165932 1.5813420 -10.9165932 1.5813420 2.9257679 190s [337] 1.5813420 1.5813420 1.5813420 1.5813420 1.5813420 2.9257679 190s [343] 1.5813420 -8.0465953 2.9257679 2.9257679 -8.0465953 0.1978277 190s [349] -8.0465953 1.5813420 1.5813420 1.5813420 2.9257679 190s 190s $se.fit 190s [1] 0.3179632 0.3179632 0.4944930 0.5940988 0.4944930 0.4944930 0.5551694 190s [8] 0.5551694 0.4944930 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 190s [15] 0.3179632 0.3179632 0.3179632 0.3179632 0.5551694 0.3179632 0.3179632 190s [22] 0.5551694 0.4944930 0.4944930 0.5551694 0.5551694 0.5940988 0.3179632 190s [29] 0.5940988 0.5940988 0.4944930 0.5551694 0.5590023 0.3179632 0.5551694 190s [36] 0.4944930 0.4944930 0.3179632 0.4944930 0.5940988 0.3179632 0.3179632 190s [43] 0.3179632 0.5940988 0.3179632 0.3179632 0.5590023 0.3179632 0.4944930 190s [50] 0.4944930 0.3179632 0.5551694 0.3179632 0.3179632 0.5551694 0.3179632 190s [57] 0.5551694 0.4944930 0.3179632 0.5940988 0.3179632 0.4944930 0.3179632 190s [64] 0.4944930 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 190s [71] 0.3179632 0.5940988 0.3179632 0.3179632 0.5551694 0.4944930 0.5551694 190s [78] 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.5940988 190s [85] 0.3179632 0.3179632 0.3179632 0.5551694 0.5551694 0.5551694 0.5551694 190s [92] 0.5940988 0.3179632 0.3179632 0.5940988 0.3179632 0.3179632 0.5940988 190s [99] 0.3179632 0.5551694 0.3179632 0.5551694 0.5940988 0.5940988 0.5940988 190s [106] 0.3179632 0.4944930 0.3179632 0.5940988 0.5551694 0.4944930 0.5940988 190s [113] 0.3179632 0.5551694 0.3179632 0.5551694 0.4944930 0.3179632 0.5551694 190s [120] 0.3179632 0.5590023 0.4944930 0.3179632 0.3179632 0.5551694 0.3179632 190s [127] 0.5940988 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 0.3179632 190s [134] 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.4944930 0.5551694 190s [141] 0.5590023 0.3179632 0.5551694 0.3179632 0.4944930 0.3179632 0.5590023 190s [148] 0.3179632 0.5551694 0.5551694 0.5940988 0.4944930 0.5551694 0.5940988 190s [155] 0.4944930 0.5940988 0.5590023 0.5590023 0.3179632 0.5551694 0.3179632 190s [162] 0.3179632 0.5940988 0.5940988 0.3179632 0.3179632 0.3179632 0.3179632 190s [169] 0.5940988 0.5590023 0.5551694 0.4944930 0.3179632 0.5590023 0.3179632 190s [176] 0.4944930 0.4944930 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 190s [183] 0.5940988 0.4944930 0.5551694 0.3179632 0.3179632 0.3179632 0.5940988 190s [190] 0.4944930 0.3179632 0.4944930 0.5940988 0.4944930 0.3179632 0.3179632 190s [197] 0.3179632 0.5551694 0.5590023 0.5940988 0.3179632 0.5940988 0.3179632 190s [204] 0.5551694 0.3179632 0.4944930 0.3179632 0.4944930 0.3179632 0.5940988 190s [211] 0.5940988 0.3179632 0.4944930 0.4944930 0.5940988 0.5551694 0.4944930 190s [218] 0.3179632 0.3179632 0.5551694 0.4944930 0.3179632 0.3179632 0.5551694 190s [225] 0.4944930 0.5590023 0.3179632 0.5940988 0.3179632 0.5551694 0.3179632 190s [232] 0.3179632 0.4944930 0.5551694 0.3179632 0.3179632 0.4944930 0.5551694 190s [239] 0.4944930 0.4944930 0.3179632 0.4944930 0.5551694 0.5940988 0.3179632 190s [246] 0.4944930 0.3179632 0.3179632 0.4944930 0.5940988 0.5551694 0.5551694 190s [253] 0.5590023 0.5940988 0.3179632 0.5940988 0.4944930 0.5551694 0.3179632 190s [260] 0.3179632 0.3179632 0.3179632 0.5590023 0.5551694 0.5551694 0.5551694 190s [267] 0.5551694 0.5551694 0.5551694 0.3179632 0.4944930 0.4944930 0.5940988 190s [274] 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 0.4944930 190s [281] 0.3179632 0.3179632 0.3179632 0.3179632 0.5940988 0.4944930 0.3179632 190s [288] 0.5590023 0.5551694 0.3179632 0.3179632 0.5551694 0.5940988 0.3179632 190s [295] 0.5551694 0.5551694 0.4944930 0.5551694 0.3179632 0.4944930 0.3179632 190s [302] 0.3179632 0.4944930 0.3179632 0.3179632 0.5940988 0.3179632 0.5940988 190s [309] 0.5590023 0.5940988 0.5940988 0.5551694 0.4944930 0.5551694 0.3179632 190s [316] 0.5940988 0.4944930 0.5551694 0.4944930 0.5590023 0.3179632 0.5551694 190s [323] 0.3179632 0.3179632 0.5551694 0.4944930 0.4944930 0.4944930 0.4944930 190s [330] 0.5590023 0.5940988 0.5551694 0.3179632 0.5551694 0.3179632 0.4944930 190s [337] 0.3179632 0.3179632 0.3179632 0.3179632 0.3179632 0.4944930 0.3179632 190s [344] 0.5940988 0.4944930 0.4944930 0.5940988 0.5590023 0.5940988 0.3179632 190s [351] 0.3179632 0.3179632 0.4944930 190s 190s [1] 50.13645 190s [1] 2052.27 190s [1] 2052.27 190s Dose Response Model 190s 190s Model: sigEmax 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -13.6642 -2.5494 -0.0589 3.1494 10.8255 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -9.3604 8.43e-01 190s eMax 18.0312 4.04e+00 190s ed50 427.8168 1.83e+02 190s h 1.3276 3.36e-01 190s age -0.0117 8.11e-03 190s centergreen -0.7488 7.57e-01 190s centerred -0.8859 7.12e-01 190s centersilver -1.4084 7.52e-01 190s centeryellow -1.4438 7.33e-01 190s 190s Residual standard error: 4.36 190s Degrees of freedom: 344 190s 190s Formula: y ~ cbind(XX, sigEmax(x, 0, 1, ed50, h)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s ed50 427.813485 182.738231 2.341 0.0198 * 190s h 1.327626 0.335875 3.953 9.38e-05 *** 190s .lin.(Intercept) -9.360422 0.842795 -11.106 < 2e-16 *** 190s .lin.centergreen -0.748766 0.757412 -0.989 0.3236 190s .lin.centerred -0.885871 0.711909 -1.244 0.2142 190s .lin.centersilver -1.408359 0.752071 -1.873 0.0620 . 190s .lin.centeryellow -1.443811 0.733469 -1.968 0.0498 * 190s .lin.age -0.011703 0.008114 -1.442 0.1501 190s .lin7 18.031101 4.042408 4.460 1.11e-05 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 4.36 on 344 degrees of freedom 190s 190s Number of iterations to convergence: 4 190s Achieved convergence tolerance: 7.015e-06 190s 190s e0 eMax ed50 h 190s e0 0.710302651 -4.248050e-01 12.9547646 5.611113e-02 190s eMax -0.424805031 1.634158e+01 694.3472385 -1.241172e+00 190s ed50 12.954764634 6.943472e+02 33394.5386095 -4.820462e+01 190s h 0.056111134 -1.241172e+00 -48.2046174 1.128111e-01 190s age -0.003282055 -7.347999e-04 -0.0251683 3.613375e-05 190s centergreen -0.239527553 2.751352e-02 1.4126289 -4.650674e-03 190s centerred -0.290825609 -1.412230e-01 -9.3345325 5.133219e-03 190s centersilver -0.296694203 -2.684223e-01 -15.5401130 1.239080e-02 190s centeryellow -0.294618448 -1.827692e-01 -11.6914478 8.045886e-03 190s age centergreen centerred centersilver 190s e0 -3.282055e-03 -0.2395275534 -2.908256e-01 -2.966942e-01 190s eMax -7.347999e-04 0.0275135152 -1.412230e-01 -2.684223e-01 190s ed50 -2.516830e-02 1.4126288560 -9.334532e+00 -1.554011e+01 190s h 3.613375e-05 -0.0046506738 5.133219e-03 1.239080e-02 190s age 6.584109e-05 -0.0004705249 3.847994e-05 1.268608e-04 190s centergreen -4.705249e-04 0.5736725480 2.674552e-01 2.669211e-01 190s centerred 3.847994e-05 0.2674552437 5.068148e-01 2.741110e-01 190s centersilver 1.268608e-04 0.2669210775 2.741110e-01 5.656114e-01 190s centeryellow 3.360823e-05 0.2672881708 2.729000e-01 2.753064e-01 190s centeryellow 190s e0 -2.946184e-01 190s eMax -1.827692e-01 190s ed50 -1.169145e+01 190s h 8.045886e-03 190s age 3.360823e-05 190s centergreen 2.672882e-01 190s centerred 2.729000e-01 190s centersilver 2.753064e-01 190s centeryellow 5.379774e-01 190s ed50 h .lin.(Intercept) .lin.centergreen 190s ed50 3.339326e+04 -4.820368e+01 12.954858536 1.4125956498 190s h -4.820368e+01 1.128119e-01 0.056111300 -0.0046506961 190s .lin.(Intercept) 1.295486e+01 5.611130e-02 0.710302646 -0.2395275486 190s .lin.centergreen 1.412596e+00 -4.650696e-03 -0.239527549 0.5736725489 190s .lin.centerred -9.334399e+00 5.133264e-03 -0.290825609 0.2674552405 190s .lin.centersilver -1.553987e+01 1.239088e-02 -0.296694200 0.2669210724 190s .lin.centeryellow -1.169127e+01 8.045945e-03 -0.294618447 0.2672881668 190s .lin.age -2.516784e-02 3.613396e-05 -0.003282055 -0.0004705249 190s .lin7 6.943216e+02 -1.241157e+00 -0.424801861 0.0275129941 190s .lin.centerred .lin.centersilver .lin.centeryellow 190s ed50 -9.334399e+00 -1.553987e+01 -1.169127e+01 190s h 5.133264e-03 1.239088e-02 8.045945e-03 190s .lin.(Intercept) -2.908256e-01 -2.966942e-01 -2.946184e-01 190s .lin.centergreen 2.674552e-01 2.669211e-01 2.672882e-01 190s .lin.centerred 5.068148e-01 2.741110e-01 2.729000e-01 190s .lin.centersilver 2.741110e-01 5.656114e-01 2.753064e-01 190s .lin.centeryellow 2.729000e-01 2.753064e-01 5.379774e-01 190s .lin.age 3.847993e-05 1.268608e-04 3.360822e-05 190s .lin7 -1.412207e-01 -2.684181e-01 -1.827662e-01 190s .lin.age .lin7 190s ed50 -2.516784e-02 694.321579932 190s h 3.613396e-05 -1.241156974 190s .lin.(Intercept) -3.282055e-03 -0.424801861 190s .lin.centergreen -4.705249e-04 0.027512994 190s .lin.centerred 3.847993e-05 -0.141220710 190s .lin.centersilver 1.268608e-04 -0.268418091 190s .lin.centeryellow 3.360822e-05 -0.182766244 190s .lin.age 6.584109e-05 -0.000734791 190s .lin7 -7.347910e-04 16.341065046 190s $fit 190s [1] 0.000000 2.286007 190s 190s $se.fit 190s [1] 0.0000000 0.7638951 190s 190s $fit 190s [1] -11.353936 -9.067928 190s 190s $se.fit 190s [1] 0.7291152 0.7547668 190s 190s [1] 50.56495 190s [1] 336.0966 190s [1] 336.0966 190s Dose Response Model 190s 190s Model: logistic 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -6.606 -1.402 -0.298 1.561 5.618 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -8.93 1.09 190s eMax 7.45 1.19 190s ed50 288.28 49.89 190s delta 43.71 37.57 190s 190s Residual standard error: 2.32 190s Degrees of freedom: 69 190s 190s Formula: y ~ logistic(x, e0, emax, ed50, delta) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s e0 -8.931 1.092 -8.179 9.42e-12 *** 190s emax 7.453 1.192 6.251 2.94e-08 *** 190s ed50 288.282 49.890 5.778 1.99e-07 *** 190s delta 43.709 37.566 1.164 0.249 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 2.323 on 69 degrees of freedom 190s 190s Number of iterations to convergence: 5 190s Achieved convergence tolerance: 1.876e-07 190s 190s e0 eMax ed50 delta 190s e0 1.192360 -1.220565 45.77140 -33.34815 190s eMax -1.220565 1.421491 -43.96678 35.28563 190s ed50 45.771405 -43.966776 2488.99412 -1733.71529 190s delta -33.348146 35.285634 -1733.71529 1411.22519 190s e0 emax ed50 delta 190s e0 1.192360 -1.220566 45.77134 -33.34807 190s emax -1.220566 1.421491 -43.96671 35.28556 190s ed50 45.771344 -43.966710 2488.98697 -1733.70785 190s delta -33.348068 35.285556 -1733.70785 1411.21841 190s $fit 190s [1] 0.0000000 5.6020564 7.4419763 7.4430636 5.6020564 0.3578039 7.4430636 190s [8] 0.3578039 7.4130064 7.4419763 5.6020564 5.6020564 5.6020564 5.6020564 190s [15] 5.6020564 5.6020564 7.4130064 0.3578039 0.3578039 7.4419763 0.3578039 190s [22] 7.4430636 0.3578039 7.4419763 7.4430636 0.3578039 7.4419763 7.4419763 190s [29] 5.6020564 0.0000000 7.4419763 5.6020564 7.4130064 7.4130064 7.4430636 190s [36] 0.0000000 7.4419763 7.4430636 5.6020564 5.6020564 5.6020564 7.4419763 190s [43] 5.6020564 0.3578039 7.4130064 5.6020564 7.4419763 0.3578039 5.6020564 190s [50] 0.0000000 5.6020564 7.4130064 7.4430636 5.6020564 0.3578039 7.4419763 190s [57] 7.4130064 7.4430636 7.4419763 7.4430636 0.0000000 5.6020564 5.6020564 190s [64] 5.6020564 7.4419763 5.6020564 7.4419763 7.4130064 7.4419763 5.6020564 190s [71] 5.6020564 0.3578039 5.6020564 190s 190s $se.fit 190s [1] 0.000000 1.134891 1.131632 1.137062 1.134891 1.244804 1.137062 1.244804 190s [9] 1.051179 1.131632 1.134891 1.134891 1.134891 1.134891 1.134891 1.134891 190s [17] 1.051179 1.244804 1.244804 1.131632 1.244804 1.137062 1.244804 1.131632 190s [25] 1.137062 1.244804 1.131632 1.131632 1.134891 0.000000 1.131632 1.134891 190s [33] 1.051179 1.051179 1.137062 0.000000 1.131632 1.137062 1.134891 1.134891 190s [41] 1.134891 1.131632 1.134891 1.244804 1.051179 1.134891 1.131632 1.244804 190s [49] 1.134891 0.000000 1.134891 1.051179 1.137062 1.134891 1.244804 1.131632 190s [57] 1.051179 1.137062 1.131632 1.137062 0.000000 1.134891 1.134891 1.134891 190s [65] 1.131632 1.134891 1.131632 1.051179 1.131632 1.134891 1.134891 1.244804 190s [73] 1.134891 190s 190s $fit 190s [1] -8.920547 -3.318491 -1.478571 -1.477483 -3.318491 -8.562743 -1.477483 190s [8] -8.562743 -1.507541 -1.478571 -3.318491 -3.318491 -3.318491 -3.318491 190s [15] -3.318491 -3.318491 -1.507541 -8.562743 -8.562743 -1.478571 -8.562743 190s [22] -1.477483 -8.562743 -1.478571 -1.477483 -8.562743 -1.478571 -1.478571 190s [29] -3.318491 -8.920547 -1.478571 -3.318491 -1.507541 -1.507541 -1.477483 190s [36] -8.920547 -1.478571 -1.477483 -3.318491 -3.318491 -3.318491 -1.478571 190s [43] -3.318491 -8.562743 -1.507541 -3.318491 -1.478571 -8.562743 -3.318491 190s [50] -8.920547 -3.318491 -1.507541 -1.477483 -3.318491 -8.562743 -1.478571 190s [57] -1.507541 -1.477483 -1.478571 -1.477483 -8.920547 -3.318491 -3.318491 190s [64] -3.318491 -1.478571 -3.318491 -1.478571 -1.507541 -1.478571 -3.318491 190s [71] -3.318491 -8.562743 -3.318491 190s 190s $se.fit 190s [1] 1.0345960 0.4644528 0.4144011 0.4155112 0.4644528 0.6986843 0.4155112 190s [8] 0.6986843 0.4088615 0.4144011 0.4644528 0.4644528 0.4644528 0.4644528 190s [15] 0.4644528 0.4644528 0.4088615 0.6986843 0.6986843 0.4144011 0.6986843 190s [22] 0.4155112 0.6986843 0.4144011 0.4155112 0.6986843 0.4144011 0.4144011 190s [29] 0.4644528 1.0345960 0.4144011 0.4644528 0.4088615 0.4088615 0.4155112 190s [36] 1.0345960 0.4144011 0.4155112 0.4644528 0.4644528 0.4644528 0.4144011 190s [43] 0.4644528 0.6986843 0.4088615 0.4644528 0.4144011 0.6986843 0.4644528 190s [50] 1.0345960 0.4644528 0.4088615 0.4155112 0.4644528 0.6986843 0.4144011 190s [57] 0.4088615 0.4155112 0.4144011 0.4155112 1.0345960 0.4644528 0.4644528 190s [64] 0.4644528 0.4144011 0.4644528 0.4144011 0.4088615 0.4144011 0.4644528 190s [71] 0.4644528 0.6986843 0.4644528 190s 190s [1] 174.1673 190s [1] 345.1575 190s [1] 345.1575 190s Dose Response Model 190s 190s Model: logistic 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -6.924 -1.388 -0.179 1.618 5.265 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -8.98657 1.419 190s eMax 7.65181 1.269 190s ed50 286.51988 50.767 190s delta 43.51040 36.726 190s age -0.00402 0.011 190s centergreen -0.12880 0.873 190s centerred 0.10022 0.975 190s centersilver 0.60689 0.985 190s centeryellow 0.06974 0.968 190s 190s Residual standard error: 2.4 190s Degrees of freedom: 64 190s 190s Formula: y ~ cbind(XX, logistic(x, 0, 1, ed50, delta)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s ed50 286.519963 50.768013 5.644 4.08e-07 *** 190s delta 43.510064 36.726739 1.185 0.241 190s .lin.(Intercept) -8.986562 1.418992 -6.333 2.71e-08 *** 190s .lin.centergreen -0.128797 0.873355 -0.147 0.883 190s .lin.centerred 0.100221 0.975122 0.103 0.918 190s .lin.centersilver 0.606894 0.985016 0.616 0.540 190s .lin.centeryellow 0.069737 0.968243 0.072 0.943 190s .lin.age -0.004017 0.011024 -0.364 0.717 190s .lin7 7.651799 1.268713 6.031 8.96e-08 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 2.396 on 64 degrees of freedom 190s 190s Number of iterations to convergence: 4 190s Achieved convergence tolerance: 6.656e-06 190s 190s e0 eMax ed50 delta 190s e0 2.013542598 -1.386381624 4.801326e+01 -3.320465e+01 190s eMax -1.386381624 1.609637809 -4.594280e+01 3.537786e+01 190s ed50 48.013263925 -45.942796986 2.577339e+03 -1.719550e+03 190s delta -33.204646034 35.377861782 -1.719550e+03 1.348832e+03 190s age -0.006268645 0.001147196 1.238916e-02 -1.182615e-04 190s centergreen -0.334052153 -0.153718220 1.779756e+00 -1.607538e+00 190s centerred -0.399667176 -0.068891593 -2.561521e+00 7.131922e-01 190s centersilver -0.538856175 0.113916607 8.446386e-02 -1.524166e+00 190s centeryellow -0.463856043 -0.044371048 -3.153773e+00 1.284203e+00 190s age centergreen centerred centersilver 190s e0 -0.0062686454 -0.3340521534 -0.399667176 -0.5388561747 190s eMax 0.0011471962 -0.1537182198 -0.068891593 0.1139166068 190s ed50 0.0123891577 1.7797560819 -2.561520564 0.0844638637 190s delta -0.0001182615 -1.6075377838 0.713192228 -1.5241663474 190s age 0.0001215321 -0.0007558322 -0.001348561 -0.0006628626 190s centergreen -0.0007558322 0.7627491953 0.499187248 0.4609636575 190s centerred -0.0013485609 0.4991872483 0.950863865 0.4738663247 190s centersilver -0.0006628626 0.4609636575 0.473866325 0.9702565708 190s centeryellow -0.0003700776 0.4923423826 0.498378928 0.4677967285 190s centeryellow 190s e0 -0.4638560434 190s eMax -0.0443710477 190s ed50 -3.1537729812 190s delta 1.2842028644 190s age -0.0003700776 190s centergreen 0.4923423826 190s centerred 0.4983789279 190s centersilver 0.4677967285 190s centeryellow 0.9374951281 190s ed50 delta .lin.(Intercept) .lin.centergreen 190s ed50 2.577391e+03 -1.719586e+03 48.013675185 1.7797792085 190s delta -1.719586e+03 1.348853e+03 -33.204886930 -1.6075529969 190s .lin.(Intercept) 4.801368e+01 -3.320489e+01 2.013538892 -0.3340522689 190s .lin.centergreen 1.779779e+00 -1.607553e+00 -0.334052269 0.7627491915 190s .lin.centerred -2.561536e+00 7.132042e-01 -0.399667184 0.4991872439 190s .lin.centersilver 8.448334e-02 -1.524165e+00 -0.538856203 0.4609636569 190s .lin.centeryellow -3.153788e+00 1.284211e+00 -0.463855840 0.4923423903 190s .lin.age 1.238909e-02 -1.181868e-04 -0.006268647 -0.0007558323 190s .lin7 -4.594320e+01 3.537808e+01 -1.386377258 -0.1537180630 190s .lin.centerred .lin.centersilver .lin.centeryellow 190s ed50 -2.561536031 0.0844833421 -3.1537878657 190s delta 0.713204179 -1.5241654679 1.2842107129 190s .lin.(Intercept) -0.399667184 -0.5388562027 -0.4638558403 190s .lin.centergreen 0.499187244 0.4609636569 0.4923423903 190s .lin.centerred 0.950863862 0.4738663195 0.4983789308 190s .lin.centersilver 0.473866320 0.9702565794 0.4677967413 190s .lin.centeryellow 0.498378931 0.4677967413 0.9374951277 190s .lin.age -0.001348561 -0.0006628628 -0.0003700776 190s .lin7 -0.068891567 0.1139166792 -0.0443712829 190s .lin.age .lin7 190s ed50 0.0123890859 -45.943204762 190s delta -0.0001181868 35.378079613 190s .lin.(Intercept) -0.0062686471 -1.386377258 190s .lin.centergreen -0.0007558323 -0.153718063 190s .lin.centerred -0.0013485609 -0.068891567 190s .lin.centersilver -0.0006628628 0.113916679 190s .lin.centeryellow -0.0003700776 -0.044371283 190s .lin.age 0.0001215321 0.001147198 190s .lin7 0.0011471982 1.609632577 190s $fit 190s [1] 0.00000000 0.09322688 190s 190s $se.fit 190s [1] 0.0000000 0.4246053 190s 190s $fit 190s [1] -8.389208 -8.295981 190s 190s $se.fit 190s [1] 1.306647 1.060317 190s 190s [1] 46.37307 190s [1] -1501.193 190s [1] -1501.193 190s Dose Response Model 190s 190s Model: exponential 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -2.70e-01 -5.95e-02 7.18e-05 5.87e-02 2.44e-01 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -0.466 6.03e-03 190s e1 0.125 9.54e-02 190s delta 972.943 4.86e+02 190s 190s Residual standard error: 0.0841 190s Degrees of freedom: 710 190s 190s Formula: y ~ exponential(x, e0, e1, delta) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s e0 -0.466094 0.006025 -77.359 <2e-16 *** 190s e1 0.124504 0.095374 1.305 0.1922 190s delta 972.943160 485.901974 2.002 0.0456 * 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.08415 on 710 degrees of freedom 190s 190s Number of iterations to convergence: 0 190s Achieved convergence tolerance: 2.866e-08 190s 190s e0 e1 delta 190s e0 3.630154e-05 -0.0004207859 -2.060286 190s e1 -4.207859e-04 0.0090961445 46.252664 190s delta -2.060286e+00 46.2526644930 236100.519975 190s e0 e1 delta 190s e0 3.630155e-05 -0.0004207863 -2.060288 190s e1 -4.207863e-04 0.0090961522 46.252705 190s delta -2.060288e+00 46.2527045249 236100.728446 190s $fit 190s [1] 0.00000000 0.03271671 0.00000000 0.11169230 0.01605388 0.18278309 190s [7] 0.18278309 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 190s [13] 0.11169230 0.01605388 0.18278309 0.18278309 0.18278309 0.18278309 190s [19] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.00000000 190s [25] 0.01605388 0.00000000 0.11169230 0.00000000 0.18278309 0.03271671 190s [31] 0.18278309 0.01605388 0.00000000 0.03271671 0.00000000 0.03271671 190s [37] 0.03271671 0.11169230 0.00000000 0.03271671 0.01605388 0.18278309 190s [43] 0.01605388 0.03271671 0.01605388 0.01605388 0.01605388 0.18278309 190s [49] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 190s [55] 0.03271671 0.03271671 0.01605388 0.00000000 0.11169230 0.18278309 190s [61] 0.00000000 0.18278309 0.18278309 0.03271671 0.03271671 0.01605388 190s [67] 0.00000000 0.03271671 0.18278309 0.01605388 0.03271671 0.00000000 190s [73] 0.00000000 0.01605388 0.18278309 0.01605388 0.00000000 0.01605388 190s [79] 0.01605388 0.01605388 0.18278309 0.18278309 0.00000000 0.01605388 190s [85] 0.11169230 0.11169230 0.01605388 0.18278309 0.11169230 0.03271671 190s [91] 0.03271671 0.18278309 0.01605388 0.11169230 0.03271671 0.00000000 190s [97] 0.18278309 0.00000000 0.00000000 0.01605388 0.11169230 0.00000000 190s [103] 0.11169230 0.03271671 0.11169230 0.18278309 0.01605388 0.00000000 190s [109] 0.11169230 0.01605388 0.11169230 0.00000000 0.00000000 0.01605388 190s [115] 0.11169230 0.01605388 0.11169230 0.11169230 0.18278309 0.01605388 190s [121] 0.11169230 0.18278309 0.00000000 0.03271671 0.18278309 0.01605388 190s [127] 0.01605388 0.03271671 0.03271671 0.11169230 0.11169230 0.18278309 190s [133] 0.00000000 0.00000000 0.01605388 0.01605388 0.01605388 0.01605388 190s [139] 0.01605388 0.18278309 0.18278309 0.01605388 0.00000000 0.18278309 190s [145] 0.00000000 0.01605388 0.18278309 0.03271671 0.18278309 0.01605388 190s [151] 0.00000000 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 190s [157] 0.01605388 0.01605388 0.00000000 0.11169230 0.00000000 0.00000000 190s [163] 0.01605388 0.03271671 0.03271671 0.00000000 0.11169230 0.18278309 190s [169] 0.18278309 0.01605388 0.03271671 0.03271671 0.11169230 0.01605388 190s [175] 0.01605388 0.03271671 0.03271671 0.00000000 0.01605388 0.01605388 190s [181] 0.11169230 0.01605388 0.03271671 0.18278309 0.11169230 0.01605388 190s [187] 0.11169230 0.03271671 0.01605388 0.03271671 0.00000000 0.18278309 190s [193] 0.03271671 0.03271671 0.01605388 0.01605388 0.01605388 0.11169230 190s [199] 0.01605388 0.00000000 0.11169230 0.11169230 0.01605388 0.03271671 190s [205] 0.00000000 0.01605388 0.00000000 0.00000000 0.01605388 0.01605388 190s [211] 0.01605388 0.03271671 0.01605388 0.03271671 0.01605388 0.18278309 190s [217] 0.01605388 0.11169230 0.01605388 0.18278309 0.11169230 0.01605388 190s [223] 0.11169230 0.18278309 0.03271671 0.18278309 0.03271671 0.11169230 190s [229] 0.11169230 0.00000000 0.01605388 0.01605388 0.11169230 0.00000000 190s [235] 0.18278309 0.03271671 0.01605388 0.11169230 0.18278309 0.18278309 190s [241] 0.01605388 0.03271671 0.00000000 0.03271671 0.18278309 0.01605388 190s [247] 0.01605388 0.03271671 0.01605388 0.11169230 0.03271671 0.03271671 190s [253] 0.11169230 0.00000000 0.00000000 0.00000000 0.01605388 0.11169230 190s [259] 0.18278309 0.01605388 0.18278309 0.01605388 0.18278309 0.03271671 190s [265] 0.01605388 0.03271671 0.01605388 0.18278309 0.18278309 0.03271671 190s [271] 0.01605388 0.18278309 0.11169230 0.01605388 0.18278309 0.01605388 190s [277] 0.01605388 0.18278309 0.11169230 0.01605388 0.18278309 0.03271671 190s [283] 0.18278309 0.01605388 0.00000000 0.01605388 0.01605388 0.01605388 190s [289] 0.11169230 0.03271671 0.03271671 0.01605388 0.03271671 0.01605388 190s [295] 0.03271671 0.00000000 0.00000000 0.01605388 0.00000000 0.01605388 190s [301] 0.11169230 0.11169230 0.18278309 0.11169230 0.01605388 0.01605388 190s [307] 0.01605388 0.03271671 0.03271671 0.03271671 0.01605388 0.18278309 190s [313] 0.03271671 0.03271671 0.11169230 0.01605388 0.03271671 0.11169230 190s [319] 0.03271671 0.11169230 0.03271671 0.01605388 0.01605388 0.01605388 190s [325] 0.18278309 0.11169230 0.01605388 0.03271671 0.18278309 0.01605388 190s [331] 0.11169230 0.03271671 0.01605388 0.03271671 0.03271671 0.01605388 190s [337] 0.01605388 0.11169230 0.01605388 0.03271671 0.01605388 0.01605388 190s [343] 0.00000000 0.01605388 0.03271671 0.01605388 0.11169230 0.18278309 190s [349] 0.01605388 0.01605388 0.01605388 0.18278309 0.11169230 0.03271671 190s [355] 0.18278309 0.01605388 0.11169230 0.03271671 0.03271671 0.01605388 190s [361] 0.01605388 0.01605388 0.01605388 0.00000000 0.03271671 0.18278309 190s [367] 0.03271671 0.18278309 0.18278309 0.01605388 0.01605388 0.11169230 190s [373] 0.01605388 0.11169230 0.01605388 0.18278309 0.18278309 0.01605388 190s [379] 0.18278309 0.18278309 0.11169230 0.11169230 0.18278309 0.03271671 190s [385] 0.18278309 0.03271671 0.18278309 0.01605388 0.11169230 0.00000000 190s [391] 0.01605388 0.00000000 0.00000000 0.01605388 0.01605388 0.03271671 190s [397] 0.03271671 0.03271671 0.00000000 0.00000000 0.01605388 0.00000000 190s [403] 0.11169230 0.03271671 0.03271671 0.00000000 0.03271671 0.01605388 190s [409] 0.01605388 0.18278309 0.03271671 0.01605388 0.03271671 0.11169230 190s [415] 0.01605388 0.11169230 0.18278309 0.11169230 0.01605388 0.03271671 190s [421] 0.01605388 0.01605388 0.18278309 0.03271671 0.11169230 0.01605388 190s [427] 0.03271671 0.00000000 0.18278309 0.01605388 0.11169230 0.01605388 190s [433] 0.01605388 0.01605388 0.00000000 0.01605388 0.11169230 0.00000000 190s [439] 0.03271671 0.03271671 0.01605388 0.01605388 0.01605388 0.03271671 190s [445] 0.00000000 0.00000000 0.01605388 0.01605388 0.00000000 0.03271671 190s [451] 0.18278309 0.01605388 0.11169230 0.00000000 0.01605388 0.00000000 190s [457] 0.01605388 0.00000000 0.18278309 0.01605388 0.01605388 0.11169230 190s [463] 0.01605388 0.03271671 0.18278309 0.18278309 0.11169230 0.18278309 190s [469] 0.01605388 0.01605388 0.00000000 0.01605388 0.01605388 0.03271671 190s [475] 0.18278309 0.03271671 0.01605388 0.18278309 0.03271671 0.11169230 190s [481] 0.00000000 0.01605388 0.18278309 0.03271671 0.01605388 0.03271671 190s [487] 0.18278309 0.11169230 0.18278309 0.01605388 0.11169230 0.18278309 190s [493] 0.11169230 0.18278309 0.03271671 0.01605388 0.18278309 0.03271671 190s [499] 0.03271671 0.01605388 0.18278309 0.11169230 0.18278309 0.18278309 190s [505] 0.01605388 0.00000000 0.01605388 0.18278309 0.18278309 0.01605388 190s [511] 0.03271671 0.01605388 0.18278309 0.01605388 0.01605388 0.03271671 190s [517] 0.01605388 0.01605388 0.03271671 0.00000000 0.03271671 0.03271671 190s [523] 0.18278309 0.03271671 0.03271671 0.03271671 0.03271671 0.00000000 190s [529] 0.01605388 0.18278309 0.03271671 0.11169230 0.18278309 0.01605388 190s [535] 0.01605388 0.01605388 0.01605388 0.11169230 0.18278309 0.00000000 190s [541] 0.03271671 0.11169230 0.03271671 0.18278309 0.03271671 0.01605388 190s [547] 0.03271671 0.00000000 0.00000000 0.18278309 0.03271671 0.11169230 190s [553] 0.11169230 0.01605388 0.00000000 0.03271671 0.00000000 0.01605388 190s [559] 0.01605388 0.01605388 0.18278309 0.18278309 0.18278309 0.03271671 190s [565] 0.03271671 0.01605388 0.11169230 0.11169230 0.03271671 0.01605388 190s [571] 0.11169230 0.00000000 0.00000000 0.01605388 0.00000000 0.01605388 190s [577] 0.03271671 0.03271671 0.00000000 0.01605388 0.01605388 0.11169230 190s [583] 0.03271671 0.18278309 0.01605388 0.11169230 0.18278309 0.01605388 190s [589] 0.01605388 0.01605388 0.18278309 0.01605388 0.18278309 0.01605388 190s [595] 0.18278309 0.18278309 0.11169230 0.03271671 0.03271671 0.01605388 190s [601] 0.01605388 0.01605388 0.18278309 0.03271671 0.03271671 0.01605388 190s [607] 0.01605388 0.18278309 0.18278309 0.11169230 0.03271671 0.18278309 190s [613] 0.18278309 0.01605388 0.01605388 0.00000000 0.18278309 0.01605388 190s [619] 0.11169230 0.01605388 0.11169230 0.00000000 0.01605388 0.01605388 190s [625] 0.18278309 0.01605388 0.03271671 0.03271671 0.00000000 0.00000000 190s [631] 0.00000000 0.00000000 0.00000000 0.01605388 0.18278309 0.03271671 190s [637] 0.00000000 0.01605388 0.11169230 0.18278309 0.01605388 0.11169230 190s [643] 0.01605388 0.00000000 0.01605388 0.03271671 0.03271671 0.01605388 190s [649] 0.00000000 0.01605388 0.11169230 0.11169230 0.18278309 0.18278309 190s [655] 0.11169230 0.01605388 0.03271671 0.03271671 0.01605388 0.01605388 190s [661] 0.00000000 0.01605388 0.03271671 0.11169230 0.01605388 0.01605388 190s [667] 0.01605388 0.01605388 0.01605388 0.01605388 0.00000000 0.01605388 190s [673] 0.03271671 0.18278309 0.01605388 0.01605388 0.18278309 0.00000000 190s [679] 0.03271671 0.01605388 0.18278309 0.03271671 0.11169230 0.01605388 190s [685] 0.18278309 0.18278309 0.11169230 0.03271671 0.00000000 0.03271671 190s [691] 0.01605388 0.01605388 0.01605388 0.11169230 0.18278309 0.01605388 190s [697] 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 0.01605388 190s [703] 0.11169230 0.11169230 0.01605388 0.01605388 0.01605388 0.01605388 190s [709] 0.03271671 0.11169230 0.01605388 0.18278309 0.01605388 190s 190s $se.fit 190s [1] 0.000000000 0.006873006 0.000000000 0.011203793 0.003837298 0.008771443 190s [7] 0.008771443 0.006873006 0.011203793 0.003837298 0.006873006 0.011203793 190s [13] 0.011203793 0.003837298 0.008771443 0.008771443 0.008771443 0.008771443 190s [19] 0.003837298 0.003837298 0.008771443 0.008771443 0.008771443 0.000000000 190s [25] 0.003837298 0.000000000 0.011203793 0.000000000 0.008771443 0.006873006 190s [31] 0.008771443 0.003837298 0.000000000 0.006873006 0.000000000 0.006873006 190s [37] 0.006873006 0.011203793 0.000000000 0.006873006 0.003837298 0.008771443 190s [43] 0.003837298 0.006873006 0.003837298 0.003837298 0.003837298 0.008771443 190s [49] 0.003837298 0.003837298 0.003837298 0.003837298 0.003837298 0.003837298 190s [55] 0.006873006 0.006873006 0.003837298 0.000000000 0.011203793 0.008771443 190s [61] 0.000000000 0.008771443 0.008771443 0.006873006 0.006873006 0.003837298 190s [67] 0.000000000 0.006873006 0.008771443 0.003837298 0.006873006 0.000000000 190s [73] 0.000000000 0.003837298 0.008771443 0.003837298 0.000000000 0.003837298 190s [79] 0.003837298 0.003837298 0.008771443 0.008771443 0.000000000 0.003837298 190s [85] 0.011203793 0.011203793 0.003837298 0.008771443 0.011203793 0.006873006 190s [91] 0.006873006 0.008771443 0.003837298 0.011203793 0.006873006 0.000000000 190s [97] 0.008771443 0.000000000 0.000000000 0.003837298 0.011203793 0.000000000 190s [103] 0.011203793 0.006873006 0.011203793 0.008771443 0.003837298 0.000000000 190s [109] 0.011203793 0.003837298 0.011203793 0.000000000 0.000000000 0.003837298 190s [115] 0.011203793 0.003837298 0.011203793 0.011203793 0.008771443 0.003837298 190s [121] 0.011203793 0.008771443 0.000000000 0.006873006 0.008771443 0.003837298 190s [127] 0.003837298 0.006873006 0.006873006 0.011203793 0.011203793 0.008771443 190s [133] 0.000000000 0.000000000 0.003837298 0.003837298 0.003837298 0.003837298 190s [139] 0.003837298 0.008771443 0.008771443 0.003837298 0.000000000 0.008771443 190s [145] 0.000000000 0.003837298 0.008771443 0.006873006 0.008771443 0.003837298 190s [151] 0.000000000 0.006873006 0.003837298 0.003837298 0.003837298 0.006873006 190s [157] 0.003837298 0.003837298 0.000000000 0.011203793 0.000000000 0.000000000 190s [163] 0.003837298 0.006873006 0.006873006 0.000000000 0.011203793 0.008771443 190s [169] 0.008771443 0.003837298 0.006873006 0.006873006 0.011203793 0.003837298 190s [175] 0.003837298 0.006873006 0.006873006 0.000000000 0.003837298 0.003837298 190s [181] 0.011203793 0.003837298 0.006873006 0.008771443 0.011203793 0.003837298 190s [187] 0.011203793 0.006873006 0.003837298 0.006873006 0.000000000 0.008771443 190s [193] 0.006873006 0.006873006 0.003837298 0.003837298 0.003837298 0.011203793 190s [199] 0.003837298 0.000000000 0.011203793 0.011203793 0.003837298 0.006873006 190s [205] 0.000000000 0.003837298 0.000000000 0.000000000 0.003837298 0.003837298 190s [211] 0.003837298 0.006873006 0.003837298 0.006873006 0.003837298 0.008771443 190s [217] 0.003837298 0.011203793 0.003837298 0.008771443 0.011203793 0.003837298 190s [223] 0.011203793 0.008771443 0.006873006 0.008771443 0.006873006 0.011203793 190s [229] 0.011203793 0.000000000 0.003837298 0.003837298 0.011203793 0.000000000 190s [235] 0.008771443 0.006873006 0.003837298 0.011203793 0.008771443 0.008771443 190s [241] 0.003837298 0.006873006 0.000000000 0.006873006 0.008771443 0.003837298 190s [247] 0.003837298 0.006873006 0.003837298 0.011203793 0.006873006 0.006873006 190s [253] 0.011203793 0.000000000 0.000000000 0.000000000 0.003837298 0.011203793 190s [259] 0.008771443 0.003837298 0.008771443 0.003837298 0.008771443 0.006873006 190s [265] 0.003837298 0.006873006 0.003837298 0.008771443 0.008771443 0.006873006 190s [271] 0.003837298 0.008771443 0.011203793 0.003837298 0.008771443 0.003837298 190s [277] 0.003837298 0.008771443 0.011203793 0.003837298 0.008771443 0.006873006 190s [283] 0.008771443 0.003837298 0.000000000 0.003837298 0.003837298 0.003837298 190s [289] 0.011203793 0.006873006 0.006873006 0.003837298 0.006873006 0.003837298 190s [295] 0.006873006 0.000000000 0.000000000 0.003837298 0.000000000 0.003837298 190s [301] 0.011203793 0.011203793 0.008771443 0.011203793 0.003837298 0.003837298 190s [307] 0.003837298 0.006873006 0.006873006 0.006873006 0.003837298 0.008771443 190s [313] 0.006873006 0.006873006 0.011203793 0.003837298 0.006873006 0.011203793 190s [319] 0.006873006 0.011203793 0.006873006 0.003837298 0.003837298 0.003837298 190s [325] 0.008771443 0.011203793 0.003837298 0.006873006 0.008771443 0.003837298 190s [331] 0.011203793 0.006873006 0.003837298 0.006873006 0.006873006 0.003837298 190s [337] 0.003837298 0.011203793 0.003837298 0.006873006 0.003837298 0.003837298 190s [343] 0.000000000 0.003837298 0.006873006 0.003837298 0.011203793 0.008771443 190s [349] 0.003837298 0.003837298 0.003837298 0.008771443 0.011203793 0.006873006 190s [355] 0.008771443 0.003837298 0.011203793 0.006873006 0.006873006 0.003837298 190s [361] 0.003837298 0.003837298 0.003837298 0.000000000 0.006873006 0.008771443 190s [367] 0.006873006 0.008771443 0.008771443 0.003837298 0.003837298 0.011203793 190s [373] 0.003837298 0.011203793 0.003837298 0.008771443 0.008771443 0.003837298 190s [379] 0.008771443 0.008771443 0.011203793 0.011203793 0.008771443 0.006873006 190s [385] 0.008771443 0.006873006 0.008771443 0.003837298 0.011203793 0.000000000 190s [391] 0.003837298 0.000000000 0.000000000 0.003837298 0.003837298 0.006873006 190s [397] 0.006873006 0.006873006 0.000000000 0.000000000 0.003837298 0.000000000 190s [403] 0.011203793 0.006873006 0.006873006 0.000000000 0.006873006 0.003837298 190s [409] 0.003837298 0.008771443 0.006873006 0.003837298 0.006873006 0.011203793 190s [415] 0.003837298 0.011203793 0.008771443 0.011203793 0.003837298 0.006873006 190s [421] 0.003837298 0.003837298 0.008771443 0.006873006 0.011203793 0.003837298 190s [427] 0.006873006 0.000000000 0.008771443 0.003837298 0.011203793 0.003837298 190s [433] 0.003837298 0.003837298 0.000000000 0.003837298 0.011203793 0.000000000 190s [439] 0.006873006 0.006873006 0.003837298 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[79] 0.003835233 0.003835233 0.007313632 0.007313632 0.006025076 0.003835233 190s [85] 0.006884091 0.006884091 0.003835233 0.007313632 0.006884091 0.004212735 190s [91] 0.004212735 0.007313632 0.003835233 0.006884091 0.004212735 0.006025076 190s [97] 0.007313632 0.006025076 0.006025076 0.003835233 0.006884091 0.006025076 190s [103] 0.006884091 0.004212735 0.006884091 0.007313632 0.003835233 0.006025076 190s [109] 0.006884091 0.003835233 0.006884091 0.006025076 0.006025076 0.003835233 190s [115] 0.006884091 0.003835233 0.006884091 0.006884091 0.007313632 0.003835233 190s [121] 0.006884091 0.007313632 0.006025076 0.004212735 0.007313632 0.003835233 190s [127] 0.003835233 0.004212735 0.004212735 0.006884091 0.006884091 0.007313632 190s [133] 0.006025076 0.006025076 0.003835233 0.003835233 0.003835233 0.003835233 190s [139] 0.003835233 0.007313632 0.007313632 0.003835233 0.006025076 0.007313632 190s [145] 0.006025076 0.003835233 0.007313632 0.004212735 0.007313632 0.003835233 190s [151] 0.006025076 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 190s [157] 0.003835233 0.003835233 0.006025076 0.006884091 0.006025076 0.006025076 190s [163] 0.003835233 0.004212735 0.004212735 0.006025076 0.006884091 0.007313632 190s [169] 0.007313632 0.003835233 0.004212735 0.004212735 0.006884091 0.003835233 190s [175] 0.003835233 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 190s [181] 0.006884091 0.003835233 0.004212735 0.007313632 0.006884091 0.003835233 190s [187] 0.006884091 0.004212735 0.003835233 0.004212735 0.006025076 0.007313632 190s [193] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.006884091 190s [199] 0.003835233 0.006025076 0.006884091 0.006884091 0.003835233 0.004212735 190s [205] 0.006025076 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 190s [211] 0.003835233 0.004212735 0.003835233 0.004212735 0.003835233 0.007313632 190s [217] 0.003835233 0.006884091 0.003835233 0.007313632 0.006884091 0.003835233 190s [223] 0.006884091 0.007313632 0.004212735 0.007313632 0.004212735 0.006884091 190s [229] 0.006884091 0.006025076 0.003835233 0.003835233 0.006884091 0.006025076 190s [235] 0.007313632 0.004212735 0.003835233 0.006884091 0.007313632 0.007313632 190s [241] 0.003835233 0.004212735 0.006025076 0.004212735 0.007313632 0.003835233 190s [247] 0.003835233 0.004212735 0.003835233 0.006884091 0.004212735 0.004212735 190s [253] 0.006884091 0.006025076 0.006025076 0.006025076 0.003835233 0.006884091 190s [259] 0.007313632 0.003835233 0.007313632 0.003835233 0.007313632 0.004212735 190s [265] 0.003835233 0.004212735 0.003835233 0.007313632 0.007313632 0.004212735 190s [271] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.003835233 190s [277] 0.003835233 0.007313632 0.006884091 0.003835233 0.007313632 0.004212735 190s [283] 0.007313632 0.003835233 0.006025076 0.003835233 0.003835233 0.003835233 190s [289] 0.006884091 0.004212735 0.004212735 0.003835233 0.004212735 0.003835233 190s [295] 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 190s [301] 0.006884091 0.006884091 0.007313632 0.006884091 0.003835233 0.003835233 190s [307] 0.003835233 0.004212735 0.004212735 0.004212735 0.003835233 0.007313632 190s [313] 0.004212735 0.004212735 0.006884091 0.003835233 0.004212735 0.006884091 190s [319] 0.004212735 0.006884091 0.004212735 0.003835233 0.003835233 0.003835233 190s [325] 0.007313632 0.006884091 0.003835233 0.004212735 0.007313632 0.003835233 190s [331] 0.006884091 0.004212735 0.003835233 0.004212735 0.004212735 0.003835233 190s [337] 0.003835233 0.006884091 0.003835233 0.004212735 0.003835233 0.003835233 190s [343] 0.006025076 0.003835233 0.004212735 0.003835233 0.006884091 0.007313632 190s [349] 0.003835233 0.003835233 0.003835233 0.007313632 0.006884091 0.004212735 190s [355] 0.007313632 0.003835233 0.006884091 0.004212735 0.004212735 0.003835233 190s [361] 0.003835233 0.003835233 0.003835233 0.006025076 0.004212735 0.007313632 190s [367] 0.004212735 0.007313632 0.007313632 0.003835233 0.003835233 0.006884091 190s [373] 0.003835233 0.006884091 0.003835233 0.007313632 0.007313632 0.003835233 190s [379] 0.007313632 0.007313632 0.006884091 0.006884091 0.007313632 0.004212735 190s [385] 0.007313632 0.004212735 0.007313632 0.003835233 0.006884091 0.006025076 190s [391] 0.003835233 0.006025076 0.006025076 0.003835233 0.003835233 0.004212735 190s [397] 0.004212735 0.004212735 0.006025076 0.006025076 0.003835233 0.006025076 190s [403] 0.006884091 0.004212735 0.004212735 0.006025076 0.004212735 0.003835233 190s [409] 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 0.006884091 190s [415] 0.003835233 0.006884091 0.007313632 0.006884091 0.003835233 0.004212735 190s [421] 0.003835233 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 190s [427] 0.004212735 0.006025076 0.007313632 0.003835233 0.006884091 0.003835233 190s [433] 0.003835233 0.003835233 0.006025076 0.003835233 0.006884091 0.006025076 190s [439] 0.004212735 0.004212735 0.003835233 0.003835233 0.003835233 0.004212735 190s [445] 0.006025076 0.006025076 0.003835233 0.003835233 0.006025076 0.004212735 190s [451] 0.007313632 0.003835233 0.006884091 0.006025076 0.003835233 0.006025076 190s [457] 0.003835233 0.006025076 0.007313632 0.003835233 0.003835233 0.006884091 190s [463] 0.003835233 0.004212735 0.007313632 0.007313632 0.006884091 0.007313632 190s [469] 0.003835233 0.003835233 0.006025076 0.003835233 0.003835233 0.004212735 190s [475] 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 190s [481] 0.006025076 0.003835233 0.007313632 0.004212735 0.003835233 0.004212735 190s [487] 0.007313632 0.006884091 0.007313632 0.003835233 0.006884091 0.007313632 190s [493] 0.006884091 0.007313632 0.004212735 0.003835233 0.007313632 0.004212735 190s [499] 0.004212735 0.003835233 0.007313632 0.006884091 0.007313632 0.007313632 190s [505] 0.003835233 0.006025076 0.003835233 0.007313632 0.007313632 0.003835233 190s [511] 0.004212735 0.003835233 0.007313632 0.003835233 0.003835233 0.004212735 190s [517] 0.003835233 0.003835233 0.004212735 0.006025076 0.004212735 0.004212735 190s [523] 0.007313632 0.004212735 0.004212735 0.004212735 0.004212735 0.006025076 190s [529] 0.003835233 0.007313632 0.004212735 0.006884091 0.007313632 0.003835233 190s [535] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.006025076 190s [541] 0.004212735 0.006884091 0.004212735 0.007313632 0.004212735 0.003835233 190s [547] 0.004212735 0.006025076 0.006025076 0.007313632 0.004212735 0.006884091 190s [553] 0.006884091 0.003835233 0.006025076 0.004212735 0.006025076 0.003835233 190s [559] 0.003835233 0.003835233 0.007313632 0.007313632 0.007313632 0.004212735 190s [565] 0.004212735 0.003835233 0.006884091 0.006884091 0.004212735 0.003835233 190s [571] 0.006884091 0.006025076 0.006025076 0.003835233 0.006025076 0.003835233 190s [577] 0.004212735 0.004212735 0.006025076 0.003835233 0.003835233 0.006884091 190s [583] 0.004212735 0.007313632 0.003835233 0.006884091 0.007313632 0.003835233 190s [589] 0.003835233 0.003835233 0.007313632 0.003835233 0.007313632 0.003835233 190s [595] 0.007313632 0.007313632 0.006884091 0.004212735 0.004212735 0.003835233 190s [601] 0.003835233 0.003835233 0.007313632 0.004212735 0.004212735 0.003835233 190s [607] 0.003835233 0.007313632 0.007313632 0.006884091 0.004212735 0.007313632 190s [613] 0.007313632 0.003835233 0.003835233 0.006025076 0.007313632 0.003835233 190s [619] 0.006884091 0.003835233 0.006884091 0.006025076 0.003835233 0.003835233 190s [625] 0.007313632 0.003835233 0.004212735 0.004212735 0.006025076 0.006025076 190s [631] 0.006025076 0.006025076 0.006025076 0.003835233 0.007313632 0.004212735 190s [637] 0.006025076 0.003835233 0.006884091 0.007313632 0.003835233 0.006884091 190s [643] 0.003835233 0.006025076 0.003835233 0.004212735 0.004212735 0.003835233 190s [649] 0.006025076 0.003835233 0.006884091 0.006884091 0.007313632 0.007313632 190s [655] 0.006884091 0.003835233 0.004212735 0.004212735 0.003835233 0.003835233 190s [661] 0.006025076 0.003835233 0.004212735 0.006884091 0.003835233 0.003835233 190s [667] 0.003835233 0.003835233 0.003835233 0.003835233 0.006025076 0.003835233 190s [673] 0.004212735 0.007313632 0.003835233 0.003835233 0.007313632 0.006025076 190s [679] 0.004212735 0.003835233 0.007313632 0.004212735 0.006884091 0.003835233 190s [685] 0.007313632 0.007313632 0.006884091 0.004212735 0.006025076 0.004212735 190s [691] 0.003835233 0.003835233 0.003835233 0.006884091 0.007313632 0.003835233 190s [697] 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 0.003835233 190s [703] 0.006884091 0.006884091 0.003835233 0.003835233 0.003835233 0.003835233 190s [709] 0.004212735 0.006884091 0.003835233 0.007313632 0.003835233 190s 190s [1] 573.604 190s [1] -1502.21 190s [1] -1502.21 190s Dose Response Model 190s 190s Model: exponential 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -2.72e-01 -5.96e-02 -5.44e-06 5.59e-02 2.43e-01 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -4.57e-01 1.03e-02 190s e1 1.24e-01 9.45e-02 190s delta 9.69e+02 4.79e+02 190s age -2.46e-04 1.09e-04 190s centergreen -2.26e-03 9.93e-03 190s centerred 7.10e-03 9.88e-03 190s centersilver 1.68e-02 1.02e-02 190s centeryellow -4.45e-03 1.01e-02 190s 190s Residual standard error: 0.0838 190s Degrees of freedom: 705 190s 190s Formula: y ~ cbind(XX, exponential(x, 0, 1, delta)) 190s 190s Parameters: 190s Estimate Std. Error t value Pr(>|t|) 190s delta 9.692e+02 4.795e+02 2.021 0.0436 * 190s .lin.(Intercept) -4.574e-01 1.035e-02 -44.200 <2e-16 *** 190s .lin.centergreen -2.256e-03 9.934e-03 -0.227 0.8204 190s .lin.centerred 7.104e-03 9.875e-03 0.719 0.4721 190s .lin.centersilver 1.682e-02 1.018e-02 1.652 0.0989 . 190s .lin.centeryellow -4.446e-03 1.005e-02 -0.442 0.6584 190s .lin.age -2.463e-04 1.090e-04 -2.259 0.0242 * 190s .lin7 1.244e-01 9.455e-02 1.316 0.1886 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.0838 on 705 degrees of freedom 190s 190s Number of iterations to convergence: 7 190s Achieved convergence tolerance: 8.761e-06 190s 190s e0 e1 delta age 190s e0 1.070950e-04 -3.644584e-04 -1.760351e+00 -6.235809e-07 190s e1 -3.644584e-04 8.939486e-03 4.524835e+01 -1.892276e-07 190s delta -1.760351e+00 4.524835e+01 2.299191e+05 -9.417516e-04 190s age -6.235809e-07 -1.892276e-07 -9.417516e-04 1.188604e-08 190s centergreen -4.990019e-05 -7.223389e-05 -3.668153e-01 4.308966e-08 190s centerred -5.090480e-05 -5.257813e-05 -2.765207e-01 2.992730e-08 190s centersilver -5.269569e-05 -5.104405e-05 -2.725147e-01 5.557593e-08 190s centeryellow -5.416568e-05 -3.395837e-05 -1.820279e-01 7.695026e-08 190s centergreen centerred centersilver centeryellow 190s e0 -4.990019e-05 -5.090480e-05 -5.269569e-05 -5.416568e-05 190s e1 -7.223389e-05 -5.257813e-05 -5.104405e-05 -3.395837e-05 190s delta -3.668153e-01 -2.765207e-01 -2.725147e-01 -1.820279e-01 190s age 4.308966e-08 2.992730e-08 5.557593e-08 7.695026e-08 190s centergreen 9.869293e-05 5.105736e-05 5.114013e-05 5.107251e-05 190s centerred 5.105736e-05 9.752101e-05 5.111632e-05 5.102188e-05 190s centersilver 5.114013e-05 5.111632e-05 1.036881e-04 5.122455e-05 190s centeryellow 5.107251e-05 5.102188e-05 5.122455e-05 1.010538e-04 190s delta .lin.(Intercept) .lin.centergreen 190s delta 2.299104e+05 -1.760315e+00 -3.668084e-01 190s .lin.(Intercept) -1.760315e+00 1.070949e-04 -4.990020e-05 190s .lin.centergreen -3.668084e-01 -4.990020e-05 9.869293e-05 190s .lin.centerred -2.765154e-01 -5.090480e-05 5.105736e-05 190s .lin.centersilver -2.725097e-01 -5.269570e-05 5.114013e-05 190s .lin.centeryellow -1.820244e-01 -5.416569e-05 5.107251e-05 190s .lin.age -9.417341e-04 -6.235810e-07 4.308966e-08 190s .lin7 4.524658e+01 -3.644504e-04 -7.223243e-05 190s .lin.centerred .lin.centersilver .lin.centeryellow 190s delta -2.765154e-01 -2.725097e-01 -1.820244e-01 190s .lin.(Intercept) -5.090480e-05 -5.269570e-05 -5.416569e-05 190s .lin.centergreen 5.105736e-05 5.114013e-05 5.107251e-05 190s .lin.centerred 9.752101e-05 5.111632e-05 5.102188e-05 190s .lin.centersilver 5.111632e-05 1.036881e-04 5.122455e-05 190s .lin.centeryellow 5.102188e-05 5.122455e-05 1.010538e-04 190s .lin.age 2.992730e-08 5.557593e-08 7.695026e-08 190s .lin7 -5.257703e-05 -5.104303e-05 -3.395768e-05 190s .lin.age .lin7 190s delta -9.417341e-04 4.524658e+01 190s .lin.(Intercept) -6.235810e-07 -3.644504e-04 190s .lin.centergreen 4.308966e-08 -7.223243e-05 190s .lin.centerred 2.992730e-08 -5.257703e-05 190s .lin.centersilver 5.557593e-08 -5.104303e-05 190s .lin.centeryellow 7.695026e-08 -3.395768e-05 190s .lin.age 1.188604e-08 -1.892238e-07 190s .lin7 -1.892238e-07 8.939124e-03 190s $fit 190s [1] 0.00000000 0.01352276 190s 190s $se.fit 190s [1] 0.000000000 0.003277925 190s 190s $fit 190s [1] -0.4697265 -0.4562037 190s 190s $se.fit 190s [1] 0.008628557 0.007549824 190s 190s [1] 571.7033 190s [1] 4189.744 190s [1] 4189.744 190s Dose Response Model 190s 190s Model: linear 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -20.3923 -4.1973 -0.0226 3.8448 25.3694 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -11.2122 0.393654 190s delta 0.0136 0.000531 190s 190s Residual standard error: 6.43 190s Degrees of freedom: 636 190s 190s Call: 190s lm(formula = y ~ x, data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -25.3694 -3.8448 0.0226 4.1973 20.3923 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -1.121e+01 3.937e-01 -28.48 <2e-16 *** 190s x 1.358e-02 5.313e-04 25.57 <2e-16 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 6.433 on 636 degrees of freedom 190s Multiple R-squared: 0.5069, Adjusted R-squared: 0.5061 190s F-statistic: 653.7 on 1 and 636 DF, p-value: < 2.2e-16 190s 190s e0 delta 190s e0 0.1549638101 -1.594693e-04 190s delta -0.0001594693 2.822434e-07 190s (Intercept) x 190s (Intercept) 0.1549638101 -1.594693e-04 190s x -0.0001594693 2.822434e-07 190s $fit 190s [1] 3.382287 6.560821 12.605469 12.605469 17.251020 0.000000 0.000000 190s [8] 6.560821 17.251020 3.382287 15.892672 3.382287 0.000000 9.671438 190s [15] 15.892672 17.251020 12.605469 17.251020 3.382287 17.251020 17.251020 190s [22] 9.671438 3.382287 12.605469 0.000000 12.605469 3.382287 6.560821 190s [29] 0.000000 17.251020 0.000000 9.671438 12.605469 3.382287 3.382287 190s [36] 0.000000 0.000000 12.605469 0.000000 12.605469 0.000000 15.892672 190s [43] 12.605469 15.892672 3.382287 17.251020 17.251020 6.560821 3.382287 190s [50] 0.000000 9.671438 17.251020 15.892672 0.000000 3.382287 17.251020 190s [57] 6.560821 17.251020 0.000000 3.382287 12.605469 12.605469 0.000000 190s [64] 0.000000 15.892672 15.892672 0.000000 12.605469 15.892672 3.382287 190s [71] 15.892672 6.560821 3.382287 17.251020 12.605469 0.000000 12.605469 190s [78] 12.605469 3.382287 0.000000 0.000000 0.000000 3.382287 3.382287 190s [85] 3.382287 6.560821 3.382287 0.000000 3.382287 17.251020 6.560821 190s [92] 3.382287 17.251020 9.671438 3.382287 0.000000 3.382287 3.382287 190s [99] 12.605469 0.000000 3.382287 3.382287 12.605469 0.000000 0.000000 190s [106] 17.251020 0.000000 6.560821 15.892672 17.251020 3.382287 17.251020 190s [113] 3.382287 0.000000 0.000000 3.382287 6.560821 0.000000 6.560821 190s [120] 3.382287 0.000000 0.000000 6.560821 15.892672 12.605469 12.605469 190s [127] 0.000000 17.251020 0.000000 17.251020 3.382287 0.000000 12.605469 190s [134] 17.251020 0.000000 3.382287 0.000000 6.560821 6.560821 6.560821 190s [141] 3.382287 17.251020 0.000000 0.000000 3.382287 0.000000 15.892672 190s [148] 17.251020 3.382287 15.892672 0.000000 17.251020 6.560821 3.382287 190s [155] 12.605469 6.560821 6.560821 3.382287 3.382287 0.000000 3.382287 190s [162] 0.000000 3.382287 12.605469 3.382287 0.000000 17.251020 0.000000 190s [169] 0.000000 3.382287 17.251020 3.382287 17.251020 15.892672 6.560821 190s [176] 12.605469 3.382287 0.000000 12.605469 0.000000 12.605469 17.251020 190s [183] 12.605469 0.000000 0.000000 12.605469 3.382287 12.605469 17.251020 190s [190] 3.382287 3.382287 17.251020 3.382287 6.560821 3.382287 17.251020 190s [197] 17.251020 0.000000 12.605469 0.000000 12.605469 3.382287 6.560821 190s [204] 12.605469 12.605469 3.382287 3.382287 12.605469 17.251020 12.605469 190s [211] 3.382287 3.382287 17.251020 0.000000 6.560821 3.382287 3.382287 190s [218] 0.000000 6.560821 0.000000 6.560821 6.560821 3.382287 0.000000 190s [225] 3.382287 3.382287 17.251020 3.382287 0.000000 17.251020 3.382287 190s [232] 6.560821 17.251020 0.000000 0.000000 3.382287 3.382287 12.605469 190s [239] 6.560821 12.605469 3.382287 12.605469 17.251020 6.560821 17.251020 190s [246] 17.251020 15.892672 0.000000 3.382287 3.382287 3.382287 0.000000 190s [253] 12.605469 15.892672 6.560821 3.382287 3.382287 0.000000 0.000000 190s [260] 12.605469 6.560821 3.382287 3.382287 12.605469 17.251020 0.000000 190s [267] 6.560821 15.892672 3.382287 15.892672 3.382287 12.605469 0.000000 190s [274] 17.251020 15.892672 6.560821 3.382287 12.605469 0.000000 3.382287 190s [281] 3.382287 12.605469 3.382287 0.000000 17.251020 15.892672 17.251020 190s [288] 3.382287 17.251020 3.382287 3.382287 3.382287 15.892672 0.000000 190s [295] 0.000000 17.251020 17.251020 12.605469 0.000000 12.605469 17.251020 190s [302] 15.892672 15.892672 0.000000 3.382287 12.605469 12.605469 15.892672 190s [309] 6.560821 15.892672 12.605469 12.605469 17.251020 0.000000 17.251020 190s [316] 3.382287 17.251020 3.382287 12.605469 0.000000 6.560821 3.382287 190s [323] 0.000000 15.892672 17.251020 17.251020 17.251020 3.382287 6.560821 190s [330] 0.000000 0.000000 12.605469 12.605469 12.605469 0.000000 12.605469 190s [337] 0.000000 15.892672 6.560821 17.251020 12.605469 12.605469 6.560821 190s [344] 0.000000 0.000000 17.251020 0.000000 0.000000 12.605469 0.000000 190s [351] 3.382287 3.382287 6.560821 17.251020 9.671438 0.000000 9.671438 190s [358] 9.671438 12.605469 3.382287 12.605469 3.382287 17.251020 0.000000 190s [365] 12.605469 0.000000 3.382287 0.000000 3.382287 6.560821 0.000000 190s [372] 6.560821 6.560821 17.251020 15.892672 0.000000 17.251020 0.000000 190s [379] 3.382287 17.251020 3.382287 12.605469 3.382287 3.382287 12.605469 190s [386] 3.382287 3.382287 0.000000 15.892672 0.000000 12.605469 0.000000 190s [393] 15.892672 6.560821 15.892672 15.892672 6.560821 6.560821 3.382287 190s [400] 3.382287 17.251020 17.251020 6.560821 12.605469 9.671438 15.892672 190s [407] 17.251020 6.560821 3.382287 0.000000 6.560821 6.560821 15.892672 190s [414] 3.382287 0.000000 0.000000 0.000000 0.000000 3.382287 3.382287 190s [421] 0.000000 3.382287 3.382287 12.605469 17.251020 17.251020 17.251020 190s [428] 0.000000 15.892672 17.251020 17.251020 0.000000 0.000000 17.251020 190s [435] 12.605469 6.560821 0.000000 0.000000 3.382287 0.000000 15.892672 190s [442] 12.605469 17.251020 3.382287 12.605469 0.000000 17.251020 0.000000 190s [449] 6.560821 12.605469 6.560821 12.605469 15.892672 12.605469 12.605469 190s [456] 0.000000 0.000000 3.382287 0.000000 3.382287 0.000000 0.000000 190s [463] 0.000000 17.251020 6.560821 17.251020 12.605469 12.605469 3.382287 190s [470] 17.251020 0.000000 3.382287 0.000000 6.560821 0.000000 0.000000 190s [477] 3.382287 15.892672 3.382287 12.605469 0.000000 3.382287 12.605469 190s [484] 6.560821 17.251020 9.671438 15.892672 17.251020 15.892672 0.000000 190s [491] 0.000000 3.382287 3.382287 17.251020 0.000000 6.560821 12.605469 190s [498] 12.605469 12.605469 3.382287 3.382287 3.382287 15.892672 0.000000 190s [505] 6.560821 3.382287 17.251020 3.382287 12.605469 12.605469 15.892672 190s [512] 0.000000 12.605469 17.251020 6.560821 0.000000 3.382287 0.000000 190s [519] 15.892672 0.000000 12.605469 12.605469 0.000000 17.251020 0.000000 190s [526] 9.671438 0.000000 3.382287 15.892672 3.382287 3.382287 3.382287 190s [533] 17.251020 15.892672 0.000000 0.000000 0.000000 15.892672 6.560821 190s [540] 17.251020 17.251020 6.560821 0.000000 0.000000 3.382287 12.605469 190s [547] 12.605469 0.000000 3.382287 15.892672 0.000000 0.000000 3.382287 190s [554] 0.000000 0.000000 0.000000 17.251020 17.251020 17.251020 12.605469 190s [561] 0.000000 15.892672 0.000000 3.382287 3.382287 12.605469 6.560821 190s [568] 12.605469 3.382287 3.382287 0.000000 17.251020 6.560821 15.892672 190s [575] 0.000000 9.671438 3.382287 3.382287 0.000000 12.605469 3.382287 190s [582] 12.605469 3.382287 0.000000 6.560821 0.000000 3.382287 17.251020 190s [589] 3.382287 12.605469 12.605469 17.251020 3.382287 9.671438 0.000000 190s [596] 17.251020 0.000000 6.560821 9.671438 9.671438 0.000000 0.000000 190s [603] 0.000000 12.605469 17.251020 12.605469 12.605469 6.560821 6.560821 190s [610] 15.892672 3.382287 6.560821 6.560821 9.671438 17.251020 17.251020 190s [617] 0.000000 3.382287 12.605469 15.892672 3.382287 0.000000 17.251020 190s [624] 12.605469 6.560821 17.251020 17.251020 0.000000 6.560821 15.892672 190s [631] 6.560821 6.560821 0.000000 15.892672 17.251020 0.000000 3.382287 190s [638] 17.251020 190s 190s $se.fit 190s [1] 0.1322852 0.2566014 0.4930147 0.4930147 0.6747076 0.0000000 0.0000000 190s [8] 0.2566014 0.6747076 0.1322852 0.6215810 0.1322852 0.0000000 0.3782613 190s [15] 0.6215810 0.6747076 0.4930147 0.6747076 0.1322852 0.6747076 0.6747076 190s [22] 0.3782613 0.1322852 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 190s [29] 0.0000000 0.6747076 0.0000000 0.3782613 0.4930147 0.1322852 0.1322852 190s [36] 0.0000000 0.0000000 0.4930147 0.0000000 0.4930147 0.0000000 0.6215810 190s [43] 0.4930147 0.6215810 0.1322852 0.6747076 0.6747076 0.2566014 0.1322852 190s [50] 0.0000000 0.3782613 0.6747076 0.6215810 0.0000000 0.1322852 0.6747076 190s [57] 0.2566014 0.6747076 0.0000000 0.1322852 0.4930147 0.4930147 0.0000000 190s [64] 0.0000000 0.6215810 0.6215810 0.0000000 0.4930147 0.6215810 0.1322852 190s [71] 0.6215810 0.2566014 0.1322852 0.6747076 0.4930147 0.0000000 0.4930147 190s [78] 0.4930147 0.1322852 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 190s [85] 0.1322852 0.2566014 0.1322852 0.0000000 0.1322852 0.6747076 0.2566014 190s [92] 0.1322852 0.6747076 0.3782613 0.1322852 0.0000000 0.1322852 0.1322852 190s [99] 0.4930147 0.0000000 0.1322852 0.1322852 0.4930147 0.0000000 0.0000000 190s [106] 0.6747076 0.0000000 0.2566014 0.6215810 0.6747076 0.1322852 0.6747076 190s [113] 0.1322852 0.0000000 0.0000000 0.1322852 0.2566014 0.0000000 0.2566014 190s [120] 0.1322852 0.0000000 0.0000000 0.2566014 0.6215810 0.4930147 0.4930147 190s [127] 0.0000000 0.6747076 0.0000000 0.6747076 0.1322852 0.0000000 0.4930147 190s [134] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.2566014 0.2566014 190s [141] 0.1322852 0.6747076 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 190s [148] 0.6747076 0.1322852 0.6215810 0.0000000 0.6747076 0.2566014 0.1322852 190s [155] 0.4930147 0.2566014 0.2566014 0.1322852 0.1322852 0.0000000 0.1322852 190s [162] 0.0000000 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.0000000 190s [169] 0.0000000 0.1322852 0.6747076 0.1322852 0.6747076 0.6215810 0.2566014 190s [176] 0.4930147 0.1322852 0.0000000 0.4930147 0.0000000 0.4930147 0.6747076 190s [183] 0.4930147 0.0000000 0.0000000 0.4930147 0.1322852 0.4930147 0.6747076 190s [190] 0.1322852 0.1322852 0.6747076 0.1322852 0.2566014 0.1322852 0.6747076 190s [197] 0.6747076 0.0000000 0.4930147 0.0000000 0.4930147 0.1322852 0.2566014 190s [204] 0.4930147 0.4930147 0.1322852 0.1322852 0.4930147 0.6747076 0.4930147 190s [211] 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.1322852 0.1322852 190s [218] 0.0000000 0.2566014 0.0000000 0.2566014 0.2566014 0.1322852 0.0000000 190s [225] 0.1322852 0.1322852 0.6747076 0.1322852 0.0000000 0.6747076 0.1322852 190s [232] 0.2566014 0.6747076 0.0000000 0.0000000 0.1322852 0.1322852 0.4930147 190s [239] 0.2566014 0.4930147 0.1322852 0.4930147 0.6747076 0.2566014 0.6747076 190s [246] 0.6747076 0.6215810 0.0000000 0.1322852 0.1322852 0.1322852 0.0000000 190s [253] 0.4930147 0.6215810 0.2566014 0.1322852 0.1322852 0.0000000 0.0000000 190s [260] 0.4930147 0.2566014 0.1322852 0.1322852 0.4930147 0.6747076 0.0000000 190s [267] 0.2566014 0.6215810 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 190s [274] 0.6747076 0.6215810 0.2566014 0.1322852 0.4930147 0.0000000 0.1322852 190s [281] 0.1322852 0.4930147 0.1322852 0.0000000 0.6747076 0.6215810 0.6747076 190s [288] 0.1322852 0.6747076 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 190s [295] 0.0000000 0.6747076 0.6747076 0.4930147 0.0000000 0.4930147 0.6747076 190s [302] 0.6215810 0.6215810 0.0000000 0.1322852 0.4930147 0.4930147 0.6215810 190s [309] 0.2566014 0.6215810 0.4930147 0.4930147 0.6747076 0.0000000 0.6747076 190s [316] 0.1322852 0.6747076 0.1322852 0.4930147 0.0000000 0.2566014 0.1322852 190s [323] 0.0000000 0.6215810 0.6747076 0.6747076 0.6747076 0.1322852 0.2566014 190s [330] 0.0000000 0.0000000 0.4930147 0.4930147 0.4930147 0.0000000 0.4930147 190s [337] 0.0000000 0.6215810 0.2566014 0.6747076 0.4930147 0.4930147 0.2566014 190s [344] 0.0000000 0.0000000 0.6747076 0.0000000 0.0000000 0.4930147 0.0000000 190s [351] 0.1322852 0.1322852 0.2566014 0.6747076 0.3782613 0.0000000 0.3782613 190s [358] 0.3782613 0.4930147 0.1322852 0.4930147 0.1322852 0.6747076 0.0000000 190s [365] 0.4930147 0.0000000 0.1322852 0.0000000 0.1322852 0.2566014 0.0000000 190s [372] 0.2566014 0.2566014 0.6747076 0.6215810 0.0000000 0.6747076 0.0000000 190s [379] 0.1322852 0.6747076 0.1322852 0.4930147 0.1322852 0.1322852 0.4930147 190s [386] 0.1322852 0.1322852 0.0000000 0.6215810 0.0000000 0.4930147 0.0000000 190s [393] 0.6215810 0.2566014 0.6215810 0.6215810 0.2566014 0.2566014 0.1322852 190s [400] 0.1322852 0.6747076 0.6747076 0.2566014 0.4930147 0.3782613 0.6215810 190s [407] 0.6747076 0.2566014 0.1322852 0.0000000 0.2566014 0.2566014 0.6215810 190s [414] 0.1322852 0.0000000 0.0000000 0.0000000 0.0000000 0.1322852 0.1322852 190s [421] 0.0000000 0.1322852 0.1322852 0.4930147 0.6747076 0.6747076 0.6747076 190s [428] 0.0000000 0.6215810 0.6747076 0.6747076 0.0000000 0.0000000 0.6747076 190s [435] 0.4930147 0.2566014 0.0000000 0.0000000 0.1322852 0.0000000 0.6215810 190s [442] 0.4930147 0.6747076 0.1322852 0.4930147 0.0000000 0.6747076 0.0000000 190s [449] 0.2566014 0.4930147 0.2566014 0.4930147 0.6215810 0.4930147 0.4930147 190s [456] 0.0000000 0.0000000 0.1322852 0.0000000 0.1322852 0.0000000 0.0000000 190s [463] 0.0000000 0.6747076 0.2566014 0.6747076 0.4930147 0.4930147 0.1322852 190s [470] 0.6747076 0.0000000 0.1322852 0.0000000 0.2566014 0.0000000 0.0000000 190s [477] 0.1322852 0.6215810 0.1322852 0.4930147 0.0000000 0.1322852 0.4930147 190s [484] 0.2566014 0.6747076 0.3782613 0.6215810 0.6747076 0.6215810 0.0000000 190s [491] 0.0000000 0.1322852 0.1322852 0.6747076 0.0000000 0.2566014 0.4930147 190s [498] 0.4930147 0.4930147 0.1322852 0.1322852 0.1322852 0.6215810 0.0000000 190s [505] 0.2566014 0.1322852 0.6747076 0.1322852 0.4930147 0.4930147 0.6215810 190s [512] 0.0000000 0.4930147 0.6747076 0.2566014 0.0000000 0.1322852 0.0000000 190s [519] 0.6215810 0.0000000 0.4930147 0.4930147 0.0000000 0.6747076 0.0000000 190s [526] 0.3782613 0.0000000 0.1322852 0.6215810 0.1322852 0.1322852 0.1322852 190s [533] 0.6747076 0.6215810 0.0000000 0.0000000 0.0000000 0.6215810 0.2566014 190s [540] 0.6747076 0.6747076 0.2566014 0.0000000 0.0000000 0.1322852 0.4930147 190s [547] 0.4930147 0.0000000 0.1322852 0.6215810 0.0000000 0.0000000 0.1322852 190s [554] 0.0000000 0.0000000 0.0000000 0.6747076 0.6747076 0.6747076 0.4930147 190s [561] 0.0000000 0.6215810 0.0000000 0.1322852 0.1322852 0.4930147 0.2566014 190s [568] 0.4930147 0.1322852 0.1322852 0.0000000 0.6747076 0.2566014 0.6215810 190s [575] 0.0000000 0.3782613 0.1322852 0.1322852 0.0000000 0.4930147 0.1322852 190s [582] 0.4930147 0.1322852 0.0000000 0.2566014 0.0000000 0.1322852 0.6747076 190s [589] 0.1322852 0.4930147 0.4930147 0.6747076 0.1322852 0.3782613 0.0000000 190s [596] 0.6747076 0.0000000 0.2566014 0.3782613 0.3782613 0.0000000 0.0000000 190s [603] 0.0000000 0.4930147 0.6747076 0.4930147 0.4930147 0.2566014 0.2566014 190s [610] 0.6215810 0.1322852 0.2566014 0.2566014 0.3782613 0.6747076 0.6747076 190s [617] 0.0000000 0.1322852 0.4930147 0.6215810 0.1322852 0.0000000 0.6747076 190s [624] 0.4930147 0.2566014 0.6747076 0.6747076 0.0000000 0.2566014 0.6215810 190s [631] 0.2566014 0.2566014 0.0000000 0.6215810 0.6747076 0.0000000 0.1322852 190s [638] 0.6747076 190s 190s [1] 73.61884 190s [1] 4193.584 190s [1] 4193.584 190s Dose Response Model 190s 190s Model: linear 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -19.855 -3.996 -0.064 3.775 24.956 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -11.1996 0.811196 190s delta 0.0136 0.000532 190s age -0.0126 0.009027 190s centergreen 0.0191 0.793736 190s centerred 1.1979 0.810341 190s centersilver 0.7446 0.817870 190s centeryellow 1.2027 0.826882 190s 190s Residual standard error: 6.43 190s Degrees of freedom: 631 190s 190s Call: 190s lm(formula = y ~ x + age + center, data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -24.956 -3.775 0.064 3.996 19.855 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -1.120e+01 8.112e-01 -13.806 <2e-16 *** 190s x 1.360e-02 5.316e-04 25.575 <2e-16 *** 190s age -1.255e-02 9.027e-03 -1.391 0.165 190s centergreen 1.906e-02 7.937e-01 0.024 0.981 190s centerred 1.198e+00 8.103e-01 1.478 0.140 190s centersilver 7.446e-01 8.179e-01 0.910 0.363 190s centeryellow 1.203e+00 8.269e-01 1.455 0.146 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 6.427 on 631 degrees of freedom 190s Multiple R-squared: 0.5116, Adjusted R-squared: 0.507 190s F-statistic: 110.2 on 6 and 631 DF, p-value: < 2.2e-16 190s 190s e0 delta age centergreen 190s e0 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 190s delta -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 190s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 190s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 190s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 190s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 190s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 190s centerred centersilver centeryellow 190s e0 -3.460807e-01 -3.642369e-01 -3.253015e-01 190s delta -1.885394e-06 1.847581e-05 3.596102e-06 190s age 2.140485e-04 3.347250e-04 -2.387489e-04 190s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 190s centerred 6.566532e-01 3.366063e-01 3.351988e-01 190s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 190s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 190s (Intercept) x age centergreen 190s (Intercept) 0.6580393306 -1.631958e-04 -4.307448e-03 -3.626158e-01 190s x -0.0001631958 2.826129e-07 -4.180339e-09 -8.076204e-07 190s age -0.0043074482 -4.180339e-09 8.148624e-05 5.148937e-04 190s centergreen -0.3626157873 -8.076204e-07 5.148937e-04 6.300174e-01 190s centerred -0.3460806667 -1.885394e-06 2.140485e-04 3.372074e-01 190s centersilver -0.3642369060 1.847581e-05 3.347250e-04 3.379136e-01 190s centeryellow -0.3253014822 3.596102e-06 -2.387489e-04 3.343312e-01 190s centerred centersilver centeryellow 190s (Intercept) -3.460807e-01 -3.642369e-01 -3.253015e-01 190s x -1.885394e-06 1.847581e-05 3.596102e-06 190s age 2.140485e-04 3.347250e-04 -2.387489e-04 190s centergreen 3.372074e-01 3.379136e-01 3.343312e-01 190s centerred 6.566532e-01 3.366063e-01 3.351988e-01 190s centersilver 3.366063e-01 6.689109e-01 3.351035e-01 190s centeryellow 3.351988e-01 3.351035e-01 6.837334e-01 190s $fit 190s [1] 3.385405 6.566871 12.617093 12.617093 17.266927 0.000000 0.000000 190s [8] 6.566871 17.266927 3.385405 15.907326 3.385405 0.000000 9.680356 190s [15] 15.907326 17.266927 12.617093 17.266927 3.385405 17.266927 17.266927 190s [22] 9.680356 3.385405 12.617093 0.000000 12.617093 3.385405 6.566871 190s [29] 0.000000 17.266927 0.000000 9.680356 12.617093 3.385405 3.385405 190s [36] 0.000000 0.000000 12.617093 0.000000 12.617093 0.000000 15.907326 190s [43] 12.617093 15.907326 3.385405 17.266927 17.266927 6.566871 3.385405 190s [50] 0.000000 9.680356 17.266927 15.907326 0.000000 3.385405 17.266927 190s [57] 6.566871 17.266927 0.000000 3.385405 12.617093 12.617093 0.000000 190s [64] 0.000000 15.907326 15.907326 0.000000 12.617093 15.907326 3.385405 190s [71] 15.907326 6.566871 3.385405 17.266927 12.617093 0.000000 12.617093 190s [78] 12.617093 3.385405 0.000000 0.000000 0.000000 3.385405 3.385405 190s [85] 3.385405 6.566871 3.385405 0.000000 3.385405 17.266927 6.566871 190s [92] 3.385405 17.266927 9.680356 3.385405 0.000000 3.385405 3.385405 190s [99] 12.617093 0.000000 3.385405 3.385405 12.617093 0.000000 0.000000 190s [106] 17.266927 0.000000 6.566871 15.907326 17.266927 3.385405 17.266927 190s [113] 3.385405 0.000000 0.000000 3.385405 6.566871 0.000000 6.566871 190s [120] 3.385405 0.000000 0.000000 6.566871 15.907326 12.617093 12.617093 190s [127] 0.000000 17.266927 0.000000 17.266927 3.385405 0.000000 12.617093 190s [134] 17.266927 0.000000 3.385405 0.000000 6.566871 6.566871 6.566871 190s [141] 3.385405 17.266927 0.000000 0.000000 3.385405 0.000000 15.907326 190s [148] 17.266927 3.385405 15.907326 0.000000 17.266927 6.566871 3.385405 190s [155] 12.617093 6.566871 6.566871 3.385405 3.385405 0.000000 3.385405 190s [162] 0.000000 3.385405 12.617093 3.385405 0.000000 17.266927 0.000000 190s [169] 0.000000 3.385405 17.266927 3.385405 17.266927 15.907326 6.566871 190s [176] 12.617093 3.385405 0.000000 12.617093 0.000000 12.617093 17.266927 190s [183] 12.617093 0.000000 0.000000 12.617093 3.385405 12.617093 17.266927 190s [190] 3.385405 3.385405 17.266927 3.385405 6.566871 3.385405 17.266927 190s [197] 17.266927 0.000000 12.617093 0.000000 12.617093 3.385405 6.566871 190s [204] 12.617093 12.617093 3.385405 3.385405 12.617093 17.266927 12.617093 190s [211] 3.385405 3.385405 17.266927 0.000000 6.566871 3.385405 3.385405 190s [218] 0.000000 6.566871 0.000000 6.566871 6.566871 3.385405 0.000000 190s [225] 3.385405 3.385405 17.266927 3.385405 0.000000 17.266927 3.385405 190s [232] 6.566871 17.266927 0.000000 0.000000 3.385405 3.385405 12.617093 190s [239] 6.566871 12.617093 3.385405 12.617093 17.266927 6.566871 17.266927 190s [246] 17.266927 15.907326 0.000000 3.385405 3.385405 3.385405 0.000000 190s [253] 12.617093 15.907326 6.566871 3.385405 3.385405 0.000000 0.000000 190s [260] 12.617093 6.566871 3.385405 3.385405 12.617093 17.266927 0.000000 190s [267] 6.566871 15.907326 3.385405 15.907326 3.385405 12.617093 0.000000 190s [274] 17.266927 15.907326 6.566871 3.385405 12.617093 0.000000 3.385405 190s [281] 3.385405 12.617093 3.385405 0.000000 17.266927 15.907326 17.266927 190s [288] 3.385405 17.266927 3.385405 3.385405 3.385405 15.907326 0.000000 190s [295] 0.000000 17.266927 17.266927 12.617093 0.000000 12.617093 17.266927 190s [302] 15.907326 15.907326 0.000000 3.385405 12.617093 12.617093 15.907326 190s [309] 6.566871 15.907326 12.617093 12.617093 17.266927 0.000000 17.266927 190s [316] 3.385405 17.266927 3.385405 12.617093 0.000000 6.566871 3.385405 190s [323] 0.000000 15.907326 17.266927 17.266927 17.266927 3.385405 6.566871 190s [330] 0.000000 0.000000 12.617093 12.617093 12.617093 0.000000 12.617093 190s [337] 0.000000 15.907326 6.566871 17.266927 12.617093 12.617093 6.566871 190s [344] 0.000000 0.000000 17.266927 0.000000 0.000000 12.617093 0.000000 190s [351] 3.385405 3.385405 6.566871 17.266927 9.680356 0.000000 9.680356 190s [358] 9.680356 12.617093 3.385405 12.617093 3.385405 17.266927 0.000000 190s [365] 12.617093 0.000000 3.385405 0.000000 3.385405 6.566871 0.000000 190s [372] 6.566871 6.566871 17.266927 15.907326 0.000000 17.266927 0.000000 190s [379] 3.385405 17.266927 3.385405 12.617093 3.385405 3.385405 12.617093 190s [386] 3.385405 3.385405 0.000000 15.907326 0.000000 12.617093 0.000000 190s [393] 15.907326 6.566871 15.907326 15.907326 6.566871 6.566871 3.385405 190s [400] 3.385405 17.266927 17.266927 6.566871 12.617093 9.680356 15.907326 190s [407] 17.266927 6.566871 3.385405 0.000000 6.566871 6.566871 15.907326 190s [414] 3.385405 0.000000 0.000000 0.000000 0.000000 3.385405 3.385405 190s [421] 0.000000 3.385405 3.385405 12.617093 17.266927 17.266927 17.266927 190s [428] 0.000000 15.907326 17.266927 17.266927 0.000000 0.000000 17.266927 190s [435] 12.617093 6.566871 0.000000 0.000000 3.385405 0.000000 15.907326 190s [442] 12.617093 17.266927 3.385405 12.617093 0.000000 17.266927 0.000000 190s [449] 6.566871 12.617093 6.566871 12.617093 15.907326 12.617093 12.617093 190s [456] 0.000000 0.000000 3.385405 0.000000 3.385405 0.000000 0.000000 190s [463] 0.000000 17.266927 6.566871 17.266927 12.617093 12.617093 3.385405 190s [470] 17.266927 0.000000 3.385405 0.000000 6.566871 0.000000 0.000000 190s [477] 3.385405 15.907326 3.385405 12.617093 0.000000 3.385405 12.617093 190s [484] 6.566871 17.266927 9.680356 15.907326 17.266927 15.907326 0.000000 190s [491] 0.000000 3.385405 3.385405 17.266927 0.000000 6.566871 12.617093 190s [498] 12.617093 12.617093 3.385405 3.385405 3.385405 15.907326 0.000000 190s [505] 6.566871 3.385405 17.266927 3.385405 12.617093 12.617093 15.907326 190s [512] 0.000000 12.617093 17.266927 6.566871 0.000000 3.385405 0.000000 190s [519] 15.907326 0.000000 12.617093 12.617093 0.000000 17.266927 0.000000 190s [526] 9.680356 0.000000 3.385405 15.907326 3.385405 3.385405 3.385405 190s [533] 17.266927 15.907326 0.000000 0.000000 0.000000 15.907326 6.566871 190s [540] 17.266927 17.266927 6.566871 0.000000 0.000000 3.385405 12.617093 190s [547] 12.617093 0.000000 3.385405 15.907326 0.000000 0.000000 3.385405 190s [554] 0.000000 0.000000 0.000000 17.266927 17.266927 17.266927 12.617093 190s [561] 0.000000 15.907326 0.000000 3.385405 3.385405 12.617093 6.566871 190s [568] 12.617093 3.385405 3.385405 0.000000 17.266927 6.566871 15.907326 190s [575] 0.000000 9.680356 3.385405 3.385405 0.000000 12.617093 3.385405 190s [582] 12.617093 3.385405 0.000000 6.566871 0.000000 3.385405 17.266927 190s [589] 3.385405 12.617093 12.617093 17.266927 3.385405 9.680356 0.000000 190s [596] 17.266927 0.000000 6.566871 9.680356 9.680356 0.000000 0.000000 190s [603] 0.000000 12.617093 17.266927 12.617093 12.617093 6.566871 6.566871 190s [610] 15.907326 3.385405 6.566871 6.566871 9.680356 17.266927 17.266927 190s [617] 0.000000 3.385405 12.617093 15.907326 3.385405 0.000000 17.266927 190s [624] 12.617093 6.566871 17.266927 17.266927 0.000000 6.566871 15.907326 190s [631] 6.566871 6.566871 0.000000 15.907326 17.266927 0.000000 3.385405 190s [638] 17.266927 190s 190s $se.fit 190s [1] 0.1323718 0.2567693 0.4933373 0.4933373 0.6751491 0.0000000 0.0000000 190s [8] 0.2567693 0.6751491 0.1323718 0.6219878 0.1323718 0.0000000 0.3785088 190s [15] 0.6219878 0.6751491 0.4933373 0.6751491 0.1323718 0.6751491 0.6751491 190s [22] 0.3785088 0.1323718 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 190s [29] 0.0000000 0.6751491 0.0000000 0.3785088 0.4933373 0.1323718 0.1323718 190s [36] 0.0000000 0.0000000 0.4933373 0.0000000 0.4933373 0.0000000 0.6219878 190s [43] 0.4933373 0.6219878 0.1323718 0.6751491 0.6751491 0.2567693 0.1323718 190s [50] 0.0000000 0.3785088 0.6751491 0.6219878 0.0000000 0.1323718 0.6751491 190s [57] 0.2567693 0.6751491 0.0000000 0.1323718 0.4933373 0.4933373 0.0000000 190s [64] 0.0000000 0.6219878 0.6219878 0.0000000 0.4933373 0.6219878 0.1323718 190s [71] 0.6219878 0.2567693 0.1323718 0.6751491 0.4933373 0.0000000 0.4933373 190s [78] 0.4933373 0.1323718 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 190s [85] 0.1323718 0.2567693 0.1323718 0.0000000 0.1323718 0.6751491 0.2567693 190s [92] 0.1323718 0.6751491 0.3785088 0.1323718 0.0000000 0.1323718 0.1323718 190s [99] 0.4933373 0.0000000 0.1323718 0.1323718 0.4933373 0.0000000 0.0000000 190s [106] 0.6751491 0.0000000 0.2567693 0.6219878 0.6751491 0.1323718 0.6751491 190s [113] 0.1323718 0.0000000 0.0000000 0.1323718 0.2567693 0.0000000 0.2567693 190s [120] 0.1323718 0.0000000 0.0000000 0.2567693 0.6219878 0.4933373 0.4933373 190s [127] 0.0000000 0.6751491 0.0000000 0.6751491 0.1323718 0.0000000 0.4933373 190s [134] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.2567693 0.2567693 190s [141] 0.1323718 0.6751491 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 190s [148] 0.6751491 0.1323718 0.6219878 0.0000000 0.6751491 0.2567693 0.1323718 190s [155] 0.4933373 0.2567693 0.2567693 0.1323718 0.1323718 0.0000000 0.1323718 190s [162] 0.0000000 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.0000000 190s [169] 0.0000000 0.1323718 0.6751491 0.1323718 0.6751491 0.6219878 0.2567693 190s [176] 0.4933373 0.1323718 0.0000000 0.4933373 0.0000000 0.4933373 0.6751491 190s [183] 0.4933373 0.0000000 0.0000000 0.4933373 0.1323718 0.4933373 0.6751491 190s [190] 0.1323718 0.1323718 0.6751491 0.1323718 0.2567693 0.1323718 0.6751491 190s [197] 0.6751491 0.0000000 0.4933373 0.0000000 0.4933373 0.1323718 0.2567693 190s [204] 0.4933373 0.4933373 0.1323718 0.1323718 0.4933373 0.6751491 0.4933373 190s [211] 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.1323718 0.1323718 190s [218] 0.0000000 0.2567693 0.0000000 0.2567693 0.2567693 0.1323718 0.0000000 190s [225] 0.1323718 0.1323718 0.6751491 0.1323718 0.0000000 0.6751491 0.1323718 190s [232] 0.2567693 0.6751491 0.0000000 0.0000000 0.1323718 0.1323718 0.4933373 190s [239] 0.2567693 0.4933373 0.1323718 0.4933373 0.6751491 0.2567693 0.6751491 190s [246] 0.6751491 0.6219878 0.0000000 0.1323718 0.1323718 0.1323718 0.0000000 190s [253] 0.4933373 0.6219878 0.2567693 0.1323718 0.1323718 0.0000000 0.0000000 190s [260] 0.4933373 0.2567693 0.1323718 0.1323718 0.4933373 0.6751491 0.0000000 190s [267] 0.2567693 0.6219878 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 190s [274] 0.6751491 0.6219878 0.2567693 0.1323718 0.4933373 0.0000000 0.1323718 190s [281] 0.1323718 0.4933373 0.1323718 0.0000000 0.6751491 0.6219878 0.6751491 190s [288] 0.1323718 0.6751491 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 190s [295] 0.0000000 0.6751491 0.6751491 0.4933373 0.0000000 0.4933373 0.6751491 190s [302] 0.6219878 0.6219878 0.0000000 0.1323718 0.4933373 0.4933373 0.6219878 190s [309] 0.2567693 0.6219878 0.4933373 0.4933373 0.6751491 0.0000000 0.6751491 190s [316] 0.1323718 0.6751491 0.1323718 0.4933373 0.0000000 0.2567693 0.1323718 190s [323] 0.0000000 0.6219878 0.6751491 0.6751491 0.6751491 0.1323718 0.2567693 190s [330] 0.0000000 0.0000000 0.4933373 0.4933373 0.4933373 0.0000000 0.4933373 190s [337] 0.0000000 0.6219878 0.2567693 0.6751491 0.4933373 0.4933373 0.2567693 190s [344] 0.0000000 0.0000000 0.6751491 0.0000000 0.0000000 0.4933373 0.0000000 190s [351] 0.1323718 0.1323718 0.2567693 0.6751491 0.3785088 0.0000000 0.3785088 190s [358] 0.3785088 0.4933373 0.1323718 0.4933373 0.1323718 0.6751491 0.0000000 190s [365] 0.4933373 0.0000000 0.1323718 0.0000000 0.1323718 0.2567693 0.0000000 190s [372] 0.2567693 0.2567693 0.6751491 0.6219878 0.0000000 0.6751491 0.0000000 190s [379] 0.1323718 0.6751491 0.1323718 0.4933373 0.1323718 0.1323718 0.4933373 190s [386] 0.1323718 0.1323718 0.0000000 0.6219878 0.0000000 0.4933373 0.0000000 190s [393] 0.6219878 0.2567693 0.6219878 0.6219878 0.2567693 0.2567693 0.1323718 190s [400] 0.1323718 0.6751491 0.6751491 0.2567693 0.4933373 0.3785088 0.6219878 190s [407] 0.6751491 0.2567693 0.1323718 0.0000000 0.2567693 0.2567693 0.6219878 190s [414] 0.1323718 0.0000000 0.0000000 0.0000000 0.0000000 0.1323718 0.1323718 190s [421] 0.0000000 0.1323718 0.1323718 0.4933373 0.6751491 0.6751491 0.6751491 190s [428] 0.0000000 0.6219878 0.6751491 0.6751491 0.0000000 0.0000000 0.6751491 190s [435] 0.4933373 0.2567693 0.0000000 0.0000000 0.1323718 0.0000000 0.6219878 190s [442] 0.4933373 0.6751491 0.1323718 0.4933373 0.0000000 0.6751491 0.0000000 190s [449] 0.2567693 0.4933373 0.2567693 0.4933373 0.6219878 0.4933373 0.4933373 190s [456] 0.0000000 0.0000000 0.1323718 0.0000000 0.1323718 0.0000000 0.0000000 190s [463] 0.0000000 0.6751491 0.2567693 0.6751491 0.4933373 0.4933373 0.1323718 190s [470] 0.6751491 0.0000000 0.1323718 0.0000000 0.2567693 0.0000000 0.0000000 190s [477] 0.1323718 0.6219878 0.1323718 0.4933373 0.0000000 0.1323718 0.4933373 190s [484] 0.2567693 0.6751491 0.3785088 0.6219878 0.6751491 0.6219878 0.0000000 190s [491] 0.0000000 0.1323718 0.1323718 0.6751491 0.0000000 0.2567693 0.4933373 190s [498] 0.4933373 0.4933373 0.1323718 0.1323718 0.1323718 0.6219878 0.0000000 190s [505] 0.2567693 0.1323718 0.6751491 0.1323718 0.4933373 0.4933373 0.6219878 190s [512] 0.0000000 0.4933373 0.6751491 0.2567693 0.0000000 0.1323718 0.0000000 190s [519] 0.6219878 0.0000000 0.4933373 0.4933373 0.0000000 0.6751491 0.0000000 190s [526] 0.3785088 0.0000000 0.1323718 0.6219878 0.1323718 0.1323718 0.1323718 190s [533] 0.6751491 0.6219878 0.0000000 0.0000000 0.0000000 0.6219878 0.2567693 190s [540] 0.6751491 0.6751491 0.2567693 0.0000000 0.0000000 0.1323718 0.4933373 190s [547] 0.4933373 0.0000000 0.1323718 0.6219878 0.0000000 0.0000000 0.1323718 190s [554] 0.0000000 0.0000000 0.0000000 0.6751491 0.6751491 0.6751491 0.4933373 190s [561] 0.0000000 0.6219878 0.0000000 0.1323718 0.1323718 0.4933373 0.2567693 190s [568] 0.4933373 0.1323718 0.1323718 0.0000000 0.6751491 0.2567693 0.6219878 190s [575] 0.0000000 0.3785088 0.1323718 0.1323718 0.0000000 0.4933373 0.1323718 190s [582] 0.4933373 0.1323718 0.0000000 0.2567693 0.0000000 0.1323718 0.6751491 190s [589] 0.1323718 0.4933373 0.4933373 0.6751491 0.1323718 0.3785088 0.0000000 190s [596] 0.6751491 0.0000000 0.2567693 0.3785088 0.3785088 0.0000000 0.0000000 190s [603] 0.0000000 0.4933373 0.6751491 0.4933373 0.4933373 0.2567693 0.2567693 190s [610] 0.6219878 0.1323718 0.2567693 0.2567693 0.3785088 0.6751491 0.6751491 190s [617] 0.0000000 0.1323718 0.4933373 0.6219878 0.1323718 0.0000000 0.6751491 190s [624] 0.4933373 0.2567693 0.6751491 0.6751491 0.0000000 0.2567693 0.6219878 190s [631] 0.2567693 0.2567693 0.0000000 0.6219878 0.6751491 0.0000000 0.1323718 190s [638] 0.6751491 190s 190s $fit 190s [1] -11.57621 -11.56261 -11.54901 -10.21661 190s 190s $se.fit 190s [1] 0.6876991 0.6874618 0.6872248 0.6656515 190s 190s $fit 190s 1 2 3 4 190s -11.57621 -11.56261 -11.54901 -10.21661 190s 190s $se.fit 190s 1 2 3 4 190s 0.6876991 0.6874618 0.6872248 0.6656515 190s 190s $df 190s [1] 631 190s 190s $residual.scale 190s [1] 6.427248 190s 190s [1] 73.55102 190s [1] 2768.739 190s [1] 2768.739 190s Dose Response Model 190s 190s Model: linlog 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -18.804 -3.875 -0.163 4.453 17.258 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -13.65 2.626 190s delta 2.21 0.402 190s 190s Residual standard error: 6.12 190s Degrees of freedom: 426 190s 190s Call: 190s lm(formula = y ~ log(x + off), data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -17.2582 -4.4526 0.1627 3.8749 18.8035 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -13.6486 2.6260 -5.197 3.14e-07 *** 190s log(x + off) 2.2117 0.4016 5.508 6.29e-08 *** 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 6.116 on 426 degrees of freedom 190s Multiple R-squared: 0.06648, Adjusted R-squared: 0.06429 190s F-statistic: 30.34 on 1 and 426 DF, p-value: 6.29e-08 190s 190s e0 delta 190s e0 6.896082 -1.0477868 190s delta -1.047787 0.1612436 190s (Intercept) log(x + off) 190s (Intercept) 6.896082 -1.0477868 190s log(x + off) -1.047787 0.1612436 190s $fit 190s [1] 6.008369 5.658359 0.000000 4.514640 4.877164 4.115493 6.008369 6.641510 190s [9] 0.000000 4.115493 5.658359 6.247655 4.514640 6.247655 4.514640 4.514640 190s [17] 4.115493 0.000000 6.008369 4.877164 4.877164 6.247655 6.733679 6.247655 190s [25] 4.115493 4.877164 0.000000 6.733679 6.641510 4.514640 4.514640 5.658359 190s [33] 6.008369 4.877164 4.877164 0.000000 6.008369 6.733679 4.877164 6.008369 190s [41] 6.733679 4.877164 6.008369 6.008369 4.877164 5.658359 4.514640 4.877164 190s [49] 0.000000 4.514640 5.658359 0.000000 4.877164 6.733679 4.877164 4.514640 190s [57] 4.877164 5.658359 6.641510 4.877164 6.733679 5.658359 0.000000 6.247655 190s [65] 6.247655 5.658359 4.877164 4.877164 4.115493 4.877164 6.733679 6.247655 190s [73] 5.658359 5.658359 4.877164 5.535104 6.008369 5.535104 6.247655 6.008369 190s [81] 6.247655 6.008369 5.535104 4.115493 5.658359 4.877164 6.008369 4.877164 190s [89] 6.247655 0.000000 6.008369 4.514640 4.514640 6.008369 4.877164 5.658359 190s [97] 4.877164 6.008369 6.733679 5.658359 4.115493 6.247655 0.000000 6.008369 190s [105] 6.247655 4.877164 6.733679 5.658359 4.115493 5.658359 5.658359 5.658359 190s [113] 6.008369 6.008369 6.733679 4.115493 4.877164 4.115493 4.877164 5.658359 190s [121] 4.514640 6.247655 4.877164 6.641510 4.115493 4.877164 5.658359 4.877164 190s [129] 4.514640 0.000000 6.008369 4.514640 6.733679 4.877164 4.514640 4.877164 190s [137] 5.658359 5.658359 4.115493 6.247655 6.641510 4.877164 5.658359 4.514640 190s [145] 4.115493 4.115493 6.733679 4.877164 0.000000 4.877164 5.658359 4.514640 190s [153] 6.641510 4.514640 4.877164 4.115493 6.247655 4.115493 6.008369 4.877164 190s [161] 4.514640 4.115493 4.877164 6.733679 6.247655 4.514640 4.877164 5.658359 190s [169] 4.115493 0.000000 5.658359 5.658359 4.877164 4.514640 4.115493 4.877164 190s [177] 0.000000 5.658359 6.247655 6.733679 0.000000 6.008369 4.514640 4.877164 190s [185] 0.000000 6.733679 5.658359 6.247655 4.514640 5.535104 5.658359 4.877164 190s [193] 5.658359 6.733679 6.641510 4.514640 6.008369 4.115493 4.877164 4.877164 190s [201] 4.115493 6.247655 5.658359 6.247655 5.535104 0.000000 4.115493 6.641510 190s [209] 6.247655 6.008369 4.115493 4.514640 4.514640 6.641510 6.733679 6.733679 190s [217] 5.658359 5.658359 6.008369 4.115493 5.658359 6.641510 6.641510 4.877164 190s [225] 0.000000 4.877164 0.000000 4.115493 4.877164 5.535104 4.115493 5.658359 190s [233] 6.733679 4.514640 6.733679 4.514640 4.514640 5.658359 6.008369 5.658359 190s [241] 4.877164 4.514640 4.115493 4.115493 4.115493 6.247655 5.658359 0.000000 190s [249] 4.115493 4.514640 6.247655 6.733679 6.008369 4.877164 4.115493 4.514640 190s [257] 0.000000 0.000000 5.658359 5.658359 4.514640 5.658359 4.514640 4.115493 190s [265] 4.877164 4.877164 4.514640 5.658359 6.008369 4.514640 4.115493 0.000000 190s [273] 4.877164 4.877164 4.115493 6.008369 4.514640 6.008369 4.514640 4.877164 190s [281] 6.008369 0.000000 0.000000 5.658359 6.247655 6.008369 6.008369 6.247655 190s [289] 4.877164 4.877164 4.514640 6.008369 6.008369 4.115493 6.641510 6.733679 190s [297] 4.514640 4.877164 4.877164 4.877164 6.008369 6.641510 4.877164 5.658359 190s [305] 4.514640 5.535104 4.877164 6.008369 6.008369 5.658359 4.514640 6.008369 190s [313] 6.247655 5.658359 6.733679 6.008369 6.247655 5.658359 5.535104 4.877164 190s [321] 5.658359 4.877164 4.877164 5.658359 5.658359 4.877164 4.115493 4.877164 190s [329] 5.658359 4.877164 4.877164 4.877164 5.658359 6.733679 6.008369 6.247655 190s [337] 4.877164 5.535104 6.008369 4.115493 6.008369 6.247655 4.115493 6.008369 190s [345] 5.658359 4.877164 6.247655 6.641510 5.658359 4.115493 6.733679 6.008369 190s [353] 5.658359 4.115493 4.514640 4.877164 6.733679 5.658359 0.000000 6.641510 190s [361] 6.733679 4.115493 6.247655 4.877164 4.877164 5.658359 4.514640 4.115493 190s [369] 4.877164 4.877164 4.877164 5.658359 4.877164 0.000000 5.658359 4.877164 190s [377] 4.877164 4.514640 4.514640 6.733679 6.008369 6.733679 4.514640 4.514640 190s [385] 4.115493 5.535104 4.877164 4.877164 6.247655 5.658359 6.733679 4.514640 190s [393] 4.877164 5.658359 6.733679 6.733679 4.514640 6.008369 5.658359 6.733679 190s [401] 6.733679 6.733679 0.000000 6.641510 6.733679 4.115493 4.877164 6.247655 190s [409] 0.000000 4.115493 4.514640 4.877164 4.877164 4.514640 6.733679 6.247655 190s [417] 5.658359 4.877164 4.877164 0.000000 4.877164 4.877164 0.000000 6.008369 190s [425] 4.115493 4.514640 4.877164 0.000000 190s 190s $se.fit 190s [1] 1.0908488 1.0273028 0.0000000 0.8196550 0.8854731 0.7471878 1.0908488 190s [8] 1.2057987 0.0000000 0.7471878 1.0273028 1.1342924 0.8196550 1.1342924 190s [15] 0.8196550 0.8196550 0.7471878 0.0000000 1.0908488 0.8854731 0.8854731 190s [22] 1.1342924 1.2225325 1.1342924 0.7471878 0.8854731 0.0000000 1.2225325 190s [29] 1.2057987 0.8196550 0.8196550 1.0273028 1.0908488 0.8854731 0.8854731 190s [36] 0.0000000 1.0908488 1.2225325 0.8854731 1.0908488 1.2225325 0.8854731 190s [43] 1.0908488 1.0908488 0.8854731 1.0273028 0.8196550 0.8854731 0.0000000 190s [50] 0.8196550 1.0273028 0.0000000 0.8854731 1.2225325 0.8854731 0.8196550 190s [57] 0.8854731 1.0273028 1.2057987 0.8854731 1.2225325 1.0273028 0.0000000 190s [64] 1.1342924 1.1342924 1.0273028 0.8854731 0.8854731 0.7471878 0.8854731 190s [71] 1.2225325 1.1342924 1.0273028 1.0273028 0.8854731 1.0049252 1.0908488 190s [78] 1.0049252 1.1342924 1.0908488 1.1342924 1.0908488 1.0049252 0.7471878 190s [85] 1.0273028 0.8854731 1.0908488 0.8854731 1.1342924 0.0000000 1.0908488 190s [92] 0.8196550 0.8196550 1.0908488 0.8854731 1.0273028 0.8854731 1.0908488 190s [99] 1.2225325 1.0273028 0.7471878 1.1342924 0.0000000 1.0908488 1.1342924 190s [106] 0.8854731 1.2225325 1.0273028 0.7471878 1.0273028 1.0273028 1.0273028 190s [113] 1.0908488 1.0908488 1.2225325 0.7471878 0.8854731 0.7471878 0.8854731 190s [120] 1.0273028 0.8196550 1.1342924 0.8854731 1.2057987 0.7471878 0.8854731 190s [127] 1.0273028 0.8854731 0.8196550 0.0000000 1.0908488 0.8196550 1.2225325 190s [134] 0.8854731 0.8196550 0.8854731 1.0273028 1.0273028 0.7471878 1.1342924 190s [141] 1.2057987 0.8854731 1.0273028 0.8196550 0.7471878 0.7471878 1.2225325 190s [148] 0.8854731 0.0000000 0.8854731 1.0273028 0.8196550 1.2057987 0.8196550 190s [155] 0.8854731 0.7471878 1.1342924 0.7471878 1.0908488 0.8854731 0.8196550 190s [162] 0.7471878 0.8854731 1.2225325 1.1342924 0.8196550 0.8854731 1.0273028 190s [169] 0.7471878 0.0000000 1.0273028 1.0273028 0.8854731 0.8196550 0.7471878 190s [176] 0.8854731 0.0000000 1.0273028 1.1342924 1.2225325 0.0000000 1.0908488 190s [183] 0.8196550 0.8854731 0.0000000 1.2225325 1.0273028 1.1342924 0.8196550 190s [190] 1.0049252 1.0273028 0.8854731 1.0273028 1.2225325 1.2057987 0.8196550 190s [197] 1.0908488 0.7471878 0.8854731 0.8854731 0.7471878 1.1342924 1.0273028 190s [204] 1.1342924 1.0049252 0.0000000 0.7471878 1.2057987 1.1342924 1.0908488 190s [211] 0.7471878 0.8196550 0.8196550 1.2057987 1.2225325 1.2225325 1.0273028 190s [218] 1.0273028 1.0908488 0.7471878 1.0273028 1.2057987 1.2057987 0.8854731 190s [225] 0.0000000 0.8854731 0.0000000 0.7471878 0.8854731 1.0049252 0.7471878 190s [232] 1.0273028 1.2225325 0.8196550 1.2225325 0.8196550 0.8196550 1.0273028 190s [239] 1.0908488 1.0273028 0.8854731 0.8196550 0.7471878 0.7471878 0.7471878 190s [246] 1.1342924 1.0273028 0.0000000 0.7471878 0.8196550 1.1342924 1.2225325 190s [253] 1.0908488 0.8854731 0.7471878 0.8196550 0.0000000 0.0000000 1.0273028 190s [260] 1.0273028 0.8196550 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 190s [267] 0.8196550 1.0273028 1.0908488 0.8196550 0.7471878 0.0000000 0.8854731 190s [274] 0.8854731 0.7471878 1.0908488 0.8196550 1.0908488 0.8196550 0.8854731 190s [281] 1.0908488 0.0000000 0.0000000 1.0273028 1.1342924 1.0908488 1.0908488 190s [288] 1.1342924 0.8854731 0.8854731 0.8196550 1.0908488 1.0908488 0.7471878 190s [295] 1.2057987 1.2225325 0.8196550 0.8854731 0.8854731 0.8854731 1.0908488 190s [302] 1.2057987 0.8854731 1.0273028 0.8196550 1.0049252 0.8854731 1.0908488 190s [309] 1.0908488 1.0273028 0.8196550 1.0908488 1.1342924 1.0273028 1.2225325 190s [316] 1.0908488 1.1342924 1.0273028 1.0049252 0.8854731 1.0273028 0.8854731 190s [323] 0.8854731 1.0273028 1.0273028 0.8854731 0.7471878 0.8854731 1.0273028 190s [330] 0.8854731 0.8854731 0.8854731 1.0273028 1.2225325 1.0908488 1.1342924 190s [337] 0.8854731 1.0049252 1.0908488 0.7471878 1.0908488 1.1342924 0.7471878 190s [344] 1.0908488 1.0273028 0.8854731 1.1342924 1.2057987 1.0273028 0.7471878 190s [351] 1.2225325 1.0908488 1.0273028 0.7471878 0.8196550 0.8854731 1.2225325 190s [358] 1.0273028 0.0000000 1.2057987 1.2225325 0.7471878 1.1342924 0.8854731 190s [365] 0.8854731 1.0273028 0.8196550 0.7471878 0.8854731 0.8854731 0.8854731 190s [372] 1.0273028 0.8854731 0.0000000 1.0273028 0.8854731 0.8854731 0.8196550 190s [379] 0.8196550 1.2225325 1.0908488 1.2225325 0.8196550 0.8196550 0.7471878 190s [386] 1.0049252 0.8854731 0.8854731 1.1342924 1.0273028 1.2225325 0.8196550 190s [393] 0.8854731 1.0273028 1.2225325 1.2225325 0.8196550 1.0908488 1.0273028 190s [400] 1.2225325 1.2225325 1.2225325 0.0000000 1.2057987 1.2225325 0.7471878 190s [407] 0.8854731 1.1342924 0.0000000 0.7471878 0.8196550 0.8854731 0.8854731 190s [414] 0.8196550 1.2225325 1.1342924 1.0273028 0.8854731 0.8854731 0.0000000 190s [421] 0.8854731 0.8854731 0.0000000 1.0908488 0.7471878 0.8196550 0.8854731 190s [428] 0.0000000 190s 190s [1] 40.01633 190s [1] 2773.961 190s [1] 2773.961 190s Dose Response Model 190s 190s Model: linlog 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -17.993 -3.920 -0.142 4.548 17.772 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -12.53812 2.7627 190s delta 2.19176 0.4045 190s age -0.00815 0.0103 190s centergreen -0.11764 0.9231 190s centerred -1.68381 0.9385 190s centersilver -0.40779 0.9137 190s centeryellow -0.83235 0.9332 190s 190s Residual standard error: 6.12 190s Degrees of freedom: 421 190s 190s Call: 190s lm(formula = y ~ log(x + off) + age + center, data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -17.7720 -4.5476 0.1417 3.9205 17.9926 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -12.538125 2.762741 -4.538 7.41e-06 *** 190s log(x + off) 2.191761 0.404501 5.418 1.01e-07 *** 190s age -0.008153 0.010337 -0.789 0.4308 190s centergreen -0.117636 0.923131 -0.127 0.8987 190s centerred -1.683810 0.938487 -1.794 0.0735 . 190s centersilver -0.407788 0.913735 -0.446 0.6556 190s centeryellow -0.832351 0.933224 -0.892 0.3730 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 6.118 on 421 degrees of freedom 190s Multiple R-squared: 0.07685, Adjusted R-squared: 0.06369 190s F-statistic: 5.841 on 6 and 421 DF, p-value: 7.284e-06 190s 190s e0 delta age centergreen 190s e0 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 190s delta -1.065954459 0.1636213662 0.0003614495 -0.0285500750 190s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 190s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 190s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 190s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 190s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 190s centerred centersilver centeryellow 190s e0 -0.3271697994 -0.3433662837 -0.3049047728 190s delta -0.0143714026 -0.0139200933 -0.0188552161 190s age 0.0001539174 0.0004143178 0.0002799329 190s centergreen 0.4142785346 0.4148464502 0.4153997441 190s centerred 0.8807582409 0.4133097826 0.4135270947 190s centersilver 0.4133097826 0.8349108233 0.4142615949 190s centeryellow 0.4135270947 0.4142615949 0.8709075166 190s (Intercept) log(x + off) age centergreen 190s (Intercept) 7.632738169 -1.0659544595 -0.0077749645 -0.2388230420 190s log(x + off) -1.065954459 0.1636213662 0.0003614495 -0.0285500750 190s age -0.007774965 0.0003614495 0.0001068627 0.0002013374 190s centergreen -0.238823042 -0.0285500750 0.0002013374 0.8521701509 190s centerred -0.327169799 -0.0143714026 0.0001539174 0.4142785346 190s centersilver -0.343366284 -0.0139200933 0.0004143178 0.4148464502 190s centeryellow -0.304904773 -0.0188552161 0.0002799329 0.4153997441 190s centerred centersilver centeryellow 190s (Intercept) -0.3271697994 -0.3433662837 -0.3049047728 190s log(x + off) -0.0143714026 -0.0139200933 -0.0188552161 190s age 0.0001539174 0.0004143178 0.0002799329 190s centergreen 0.4142785346 0.4148464502 0.4153997441 190s centerred 0.8807582409 0.4133097826 0.4135270947 190s centersilver 0.4133097826 0.8349108233 0.4142615949 190s centeryellow 0.4135270947 0.4142615949 0.8709075166 190s $fit 190s [1] -3.511779 -3.480690 -3.450035 -1.567022 190s 190s $se.fit 190s [1] 1.1058048 1.1012159 1.0967017 0.8461873 190s 190s $fit 190s 1 2 3 4 190s -3.511779 -3.480690 -3.450035 -1.567022 190s 190s $se.fit 190s 1 2 3 4 190s 1.1058048 1.1012159 1.0967017 0.8461873 190s 190s $df 190s [1] 421 190s 190s $residual.scale 190s [1] 6.117927 190s 190s [1] 40.47058 190s [1] 54.33574 190s [1] 54.33574 190s Dose Response Model 190s 190s Model: quadratic 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -9.08e-01 -3.06e-01 3.08e-05 2.39e-01 7.57e-01 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -3.12e+00 9.19e-02 190s b1 -6.61e-04 1.47e-03 190s b2 5.18e-06 4.40e-06 190s 190s Residual standard error: 0.401 190s Degrees of freedom: 46 190s 190s Call: 190s lm(formula = y ~ x + I(x^2), data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -0.75741 -0.23947 -0.00003 0.30638 0.90831 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -3.118e+00 9.195e-02 -33.914 <2e-16 *** 190s x -6.612e-04 1.466e-03 -0.451 0.654 190s I(x^2) 5.175e-06 4.401e-06 1.176 0.246 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.4007 on 46 degrees of freedom 190s Multiple R-squared: 0.1193, Adjusted R-squared: 0.08097 190s F-statistic: 3.115 on 2 and 46 DF, p-value: 0.05388 190s 190s e0 b1 b2 190s e0 8.454726e-03 -7.868733e-05 1.608713e-07 190s b1 -7.868733e-05 2.149290e-06 -6.145868e-09 190s b2 1.608713e-07 -6.145868e-09 1.936461e-11 190s (Intercept) x I(x^2) 190s (Intercept) 8.454726e-03 -7.868733e-05 1.608713e-07 190s x -7.868733e-05 2.149290e-06 -6.145868e-09 190s I(x^2) 1.608713e-07 -6.145868e-09 1.936461e-11 190s $fit 190s [1] 0.49280484 0.00000000 0.05861756 0.00000000 0.25773527 0.00000000 190s [7] 0.05861756 0.00000000 0.25773527 0.05861756 0.25773527 -0.01991690 190s [13] 0.05861756 -0.01991690 0.05861756 0.02376374 0.05861756 0.05861756 190s [19] 0.02376374 0.49280484 0.00000000 0.49280484 0.00000000 0.05861756 190s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.02376374 190s [31] 0.25773527 0.00000000 0.25773527 -0.01991690 0.25773527 0.00000000 190s [37] 0.00000000 0.00000000 0.25773527 0.00000000 0.25773527 -0.01991690 190s [43] 0.25773527 0.02376374 0.05861756 -0.01991690 0.00000000 0.25773527 190s [49] 0.00000000 190s 190s $se.fit 190s [1] 0.19776187 0.00000000 0.13594191 0.00000000 0.13486241 0.00000000 190s [7] 0.13594191 0.00000000 0.13486241 0.13594191 0.13486241 0.09012454 190s [13] 0.13594191 0.09012454 0.13594191 0.13105561 0.13594191 0.13594191 190s [19] 0.13105561 0.19776187 0.00000000 0.19776187 0.00000000 0.13594191 190s [25] 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.13105561 190s [31] 0.13486241 0.00000000 0.13486241 0.09012454 0.13486241 0.00000000 190s [37] 0.00000000 0.00000000 0.13486241 0.00000000 0.13486241 0.09012454 190s [43] 0.13486241 0.13105561 0.13594191 0.09012454 0.00000000 0.13486241 190s [49] 0.00000000 190s 190s $fit 190s [1] -3.118383 -3.124477 -3.132746 190s 190s $se.fit 190s [1] 0.09194958 0.08435629 0.08409705 190s 190s $fit 190s 1 2 3 190s -3.118383 -3.124477 -3.132746 190s 190s $se.fit 190s 1 2 3 190s 0.09194958 0.08435629 0.08409705 190s 190s $df 190s [1] 46 190s 190s $residual.scale 190s [1] 0.4007027 190s 190s [1] 508.0679 190s [1] 62.95473 190s [1] 62.95473 190s Dose Response Model 190s 190s Model: quadratic 190s Fit-type: normal 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -0.87232 -0.24673 -0.00516 0.29930 0.65583 190s 190s Coefficients with approx. stand. error: 190s Estimate Std. Error 190s e0 -3.08e+00 1.69e-01 190s b1 -5.76e-04 1.59e-03 190s b2 4.82e-06 4.74e-06 190s age -1.60e-03 2.09e-03 190s centergreen -4.89e-03 2.03e-01 190s centerred 6.72e-02 1.75e-01 190s centersilver 7.81e-02 1.87e-01 190s centeryellow 9.70e-02 1.95e-01 190s 190s Residual standard error: 0.418 190s Degrees of freedom: 41 190s 190s Call: 190s lm(formula = y ~ x + I(x^2) + age + center, data = datset) 190s 190s Residuals: 190s Min 1Q Median 3Q Max 190s -0.65583 -0.29930 0.00516 0.24673 0.87232 190s 190s Coefficients: 190s Estimate Std. Error t value Pr(>|t|) 190s (Intercept) -3.076e+00 1.692e-01 -18.182 <2e-16 *** 190s x -5.756e-04 1.594e-03 -0.361 0.720 190s I(x^2) 4.822e-06 4.738e-06 1.018 0.315 190s age -1.604e-03 2.092e-03 -0.767 0.448 190s centergreen -4.891e-03 2.034e-01 -0.024 0.981 190s centerred 6.715e-02 1.753e-01 0.383 0.704 190s centersilver 7.814e-02 1.875e-01 0.417 0.679 190s centeryellow 9.700e-02 1.950e-01 0.497 0.622 190s --- 190s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 190s 190s Residual standard error: 0.4185 on 41 degrees of freedom 190s Multiple R-squared: 0.1437, Adjusted R-squared: -0.002451 190s F-statistic: 0.9832 on 7 and 41 DF, p-value: 0.4566 190s 190s e0 b1 b2 age 190s e0 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 190s b1 -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 190s b2 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 190s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 190s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 190s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 190s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 190s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 190s centergreen centerred centersilver centeryellow 190s e0 -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 190s b1 -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 190s b2 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 190s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 190s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 190s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 190s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 190s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 190s (Intercept) x I(x^2) age 190s (Intercept) 2.862812e-02 -7.239847e-05 1.267650e-07 -2.074072e-04 190s x -7.239847e-05 2.540221e-06 -7.184577e-09 5.108591e-08 190s I(x^2) 1.267650e-07 -7.184577e-09 2.245217e-11 3.521184e-11 190s age -2.074072e-04 5.108591e-08 3.521184e-11 4.376769e-06 190s centergreen -6.997613e-03 -8.024708e-05 1.931149e-07 -9.351576e-05 190s centerred -1.143502e-02 -7.161311e-06 3.686110e-08 -7.667700e-05 190s centersilver -1.190681e-02 -4.175985e-05 1.275528e-07 -4.035812e-05 190s centeryellow -1.311971e-02 -2.255991e-05 1.246186e-08 1.810824e-05 190s centergreen centerred centersilver centeryellow 190s (Intercept) -6.997613e-03 -1.143502e-02 -1.190681e-02 -1.311971e-02 190s x -8.024708e-05 -7.161311e-06 -4.175985e-05 -2.255991e-05 190s I(x^2) 1.931149e-07 3.686110e-08 1.275528e-07 1.246186e-08 190s age -9.351576e-05 -7.667700e-05 -4.035812e-05 1.810824e-05 190s centergreen 4.137795e-02 1.614879e-02 1.658732e-02 1.565529e-02 190s centerred 1.614879e-02 3.073191e-02 1.550655e-02 1.384931e-02 190s centersilver 1.658732e-02 1.550655e-02 3.515550e-02 1.452661e-02 190s centeryellow 1.565529e-02 1.384931e-02 1.452661e-02 3.804408e-02 190s $fit 190s [1] -3.124527 -3.129801 -3.133870 190s 190s $se.fit 190s [1] 0.1418548 0.1377349 0.1475950 190s 190s $fit 190s 1 2 3 190s -3.124527 -3.129801 -3.133870 190s 190s $se.fit 190s 1 2 3 190s 0.1418548 0.1377349 0.1475950 190s 190s $df 190s [1] 41 190s 190s $residual.scale 190s [1] 0.418494 190s 190s [1] 215.5724 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [38] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [75] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [112] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [149] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [186] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [223] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [260] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [297] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [334] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190s [1] 0 0 0 0 0 190s [1] 0 0 0 0 0 190s e0 delta 190s 0.47569910 0.02447331 190s e0 delta 190s 0.47569910 0.02447331 190s Warning message: 190s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 190s mns is not a numeric but a array, converting with as.numeric() 190s Warning message: 190s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 190s mns is not a numeric but a array, converting with as.numeric() 190s Warning message: 190s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 190s mns is not a numeric but a array, converting with as.numeric() 190s Warning message: 190s In checkAnalyArgs(dose, resp, data, S, type, addCovars, placAdj, : 190s mns is not a numeric but a array, converting with as.numeric() 190s testsFitting.R passed 190s Loading required package: DoseFinding 192s testsMCPMod.R passed 192s Loading required package: DoseFinding 193s Loading required package: multcomp 193s Loading required package: mvtnorm 193s Loading required package: survival 193s Loading required package: TH.data 193s Loading required package: MASS 193s 193s Attaching package: ‘TH.data’ 193s 193s The following object is masked from ‘package:MASS’: 193s 193s geyser 193s 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 194s 194s Linear Hypotheses: 194s Estimate Std. Error t value Pr(>t) 194s linear <= 0 0.07260 0.05755 1.262 0.1756 194s betaMod <= 0 0.12179 0.05559 2.191 0.0287 * 194s sigEmax <= 0 0.08677 0.05648 1.536 0.1114 194s --- 194s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear betaMod sigEmax 194s 0 -0.472 -0.492 -0.349 194s 172 -0.391 -0.345 -0.489 194s 285 -0.132 0.032 -0.240 194s 516 0.262 0.799 0.503 194s 761 0.733 0.007 0.574 194s 194s Contrast Correlation: 194s linear betaMod sigEmax 194s linear 1.000 0.645 0.942 194s betaMod 0.645 1.000 0.741 194s sigEmax 0.942 0.741 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s betaMod 2.191 0.0287 194s sigEmax 1.536 0.1112 194s linear 1.262 0.1757 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: lm(formula = y ~ x, data = dd2) 194s 194s Linear Hypotheses: 194s Estimate Std. Error t value Pr(>t) 194s linear <= 0 0.07985 0.05691 1.403 0.1404 194s betaMod <= 0 0.11839 0.05507 2.150 0.0314 * 194s sigEmax <= 0 0.09407 0.05594 1.682 0.0853 . 194s --- 194s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear betaMod sigEmax 194s 0 -0.472 -0.487 -0.347 194s 172 -0.389 -0.348 -0.490 194s 285 -0.132 0.030 -0.239 194s 516 0.255 0.800 0.500 194s 761 0.738 0.005 0.576 194s 194s Contrast Correlation: 194s linear betaMod sigEmax 194s linear 1.000 0.642 0.941 194s betaMod 0.642 1.000 0.740 194s sigEmax 0.941 0.740 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s betaMod 2.150 0.0317 194s sigEmax 1.682 0.0852 194s linear 1.403 0.1403 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: lm(formula = y ~ x + cov1 + cov2, data = dd2) 194s 194s Linear Hypotheses: 194s Estimate Std. Error t value Pr(>t) 194s linlog <= 0 0.09114 0.05971 1.526 0.1510 194s logistic1 <= 0 0.10293 0.05761 1.787 0.0940 . 194s logistic2 <= 0 0.09583 0.05707 1.679 0.1154 194s exponential <= 0 0.02544 0.05514 0.461 0.5623 194s quadratic <= 0 0.11676 0.05980 1.952 0.0674 . 194s --- 194s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linlog logistic1 logistic2 exponential quadratic 194s 0 -0.624 -0.448 -0.457 -0.268 -0.665 194s 172 -0.309 -0.590 -0.475 -0.347 -0.055 194s 285 -0.049 0.101 -0.118 -0.191 0.199 194s 516 0.366 0.500 0.499 -0.069 0.696 194s 761 0.616 0.437 0.550 0.875 -0.174 194s 194s Contrast Correlation: 194s linlog logistic1 logistic2 exponential quadratic 194s linlog 1.000 0.902 0.955 0.799 0.651 194s logistic1 0.902 1.000 0.949 0.671 0.660 194s logistic2 0.955 0.949 1.000 0.792 0.586 194s exponential 0.799 0.671 0.792 1.000 0.063 194s quadratic 0.651 0.660 0.586 0.063 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s quadratic 1.952 0.0675 194s logistic1 1.787 0.0941 194s logistic2 1.679 0.1154 194s linlog 1.526 0.1506 194s exponential 0.461 0.5625 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: lm(formula = y ~ x, data = dd2) 194s 194s Linear Hypotheses: 194s Estimate Std. Error t value Pr(>t) 194s linlog <= 0 0.09484 0.05913 1.604 0.1320 194s logistic1 <= 0 0.10608 0.05706 1.859 0.0817 . 194s logistic2 <= 0 0.10119 0.05654 1.790 0.0928 . 194s exponential <= 0 0.03666 0.05440 0.674 0.4665 194s quadratic <= 0 0.10792 0.05938 1.817 0.0885 . 194s --- 194s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linlog logistic1 logistic2 exponential quadratic 194s 0 -0.623 -0.445 -0.455 -0.270 -0.664 194s 172 -0.307 -0.592 -0.476 -0.342 -0.056 194s 285 -0.050 0.101 -0.118 -0.189 0.197 194s 516 0.358 0.497 0.496 -0.076 0.698 194s 761 0.622 0.440 0.554 0.877 -0.175 194s 194s Contrast Correlation: 194s linlog logistic1 logistic2 exponential quadratic 194s linlog 1.000 0.901 0.955 0.800 0.648 194s logistic1 0.901 1.000 0.949 0.670 0.658 194s logistic2 0.955 0.949 1.000 0.792 0.584 194s exponential 0.800 0.670 0.792 1.000 0.062 194s quadratic 0.648 0.658 0.584 0.062 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s logistic1 1.859 0.0816 194s quadratic 1.817 0.0887 194s logistic2 1.790 0.0933 194s linlog 1.604 0.1316 194s exponential 0.674 0.4667 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: lm(formula = y ~ x, data = dd2) 194s 194s Linear Hypotheses: 194s Estimate Std. Error t value Pr(>t) 194s linlog <= 0 -0.2995 1.0212 -0.293 0.821 194s logistic1 <= 0 -0.1795 0.9837 -0.182 0.785 194s logistic2 <= 0 -0.1401 0.9877 -0.142 0.771 194s exponential <= 0 -0.2892 0.9568 -0.302 0.823 194s quadratic <= 0 -0.1973 1.2830 -0.154 0.776 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linlog logistic1 logistic2 exponential quadratic 194s 0 -0.464 -0.268 -0.289 -0.207 -0.751 194s 124 -0.436 -0.627 -0.556 -0.450 -0.241 194s 272 0.013 -0.006 -0.083 -0.187 0.476 194s 560 0.127 0.196 0.172 -0.004 0.353 194s 865 0.761 0.705 0.755 0.848 0.164 194s 194s Contrast Correlation: 194s linlog logistic1 logistic2 exponential quadratic 194s linlog 1.000 0.950 0.963 0.890 0.665 194s logistic1 0.950 1.000 0.992 0.879 0.591 194s logistic2 0.963 0.992 1.000 0.922 0.542 194s exponential 0.890 0.879 0.922 1.000 0.252 194s quadratic 0.665 0.591 0.542 0.252 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s logistic2 -0.142 0.771 194s quadratic -0.154 0.776 194s logistic1 -0.182 0.785 194s linlog -0.293 0.821 194s exponential -0.302 0.823 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 194s 194s Linear Hypotheses: 194s Estimate Std. Error z value Pr(>z) 194s linear <= 0 0.19645 0.33561 0.585 0.395 194s betaMod <= 0 0.03813 0.31565 0.121 0.587 194s sigEmax <= 0 0.30472 0.34592 0.881 0.283 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear betaMod sigEmax 194s 0 -0.794 -0.793 -0.774 194s 190 -0.064 -0.022 -0.192 194s 344 0.197 0.577 0.317 194s 404 0.098 0.190 0.163 194s 616 0.563 0.048 0.487 194s 194s Contrast Correlation: 194s linear betaMod sigEmax 194s linear 1.000 0.723 0.962 194s betaMod 0.723 1.000 0.793 194s sigEmax 0.962 0.793 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s sigEmax 0.881 0.283 194s linear 0.585 0.395 194s betaMod 0.121 0.587 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 194s 194s Linear Hypotheses: 194s Estimate Std. Error z value Pr(>z) 194s linear <= 0 0.2547 0.1877 1.357 0.1500 194s betaMod <= 0 0.2367 0.2371 0.999 0.2555 194s sigEmax <= 0 0.3698 0.1889 1.958 0.0476 * 194s --- 194s Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear betaMod sigEmax 194s 0 0.418 0.634 0.310 194s 68.5 0.114 0.150 0.139 194s 85.9 0.387 0.362 0.551 194s 166 0.027 -0.572 -0.033 194s 197 -0.015 -0.158 -0.054 194s 278 -0.129 -0.264 -0.172 194s 332 -0.803 -0.152 -0.740 194s 194s Contrast Correlation: 194s linear betaMod sigEmax 194s linear 1.000 0.635 0.967 194s betaMod 0.635 1.000 0.677 194s sigEmax 0.967 0.677 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s sigEmax 1.958 0.0477 194s linear 1.357 0.1501 194s betaMod 0.999 0.2556 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 194s 194s Linear Hypotheses: 194s Estimate Std. Error z value Pr(>z) 194s linear <= 0 0.3391 0.3218 1.054 0.226 194s betaMod <= 0 0.3556 0.3124 1.138 0.201 194s sigEmax <= 0 0.2935 0.3497 0.839 0.299 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear betaMod sigEmax 194s 0 -0.721 -0.796 -0.547 194s 79.1 -0.129 -0.102 -0.312 194s 117 0.005 0.106 -0.137 194s 208 0.191 0.519 0.288 194s 398 0.654 0.274 0.708 194s 194s Contrast Correlation: 194s linear betaMod sigEmax 194s linear 1.000 0.785 0.954 194s betaMod 0.785 1.000 0.742 194s sigEmax 0.954 0.742 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s betaMod 1.138 0.201 194s linear 1.054 0.226 194s sigEmax 0.839 0.299 194s Warning message: 194s In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 194s Warning from mvtnorm::pmvt: univariate: using pnorm. 194s 194s Simultaneous Tests for General Linear Hypotheses 194s 194s Multiple Comparisons of Means: User-defined Contrasts 194s 194s 194s Fit: glm(formula = y ~ x - 1, family = binomial, data = dd2, weights = n) 194s 194s Linear Hypotheses: 194s Estimate Std. Error z value Pr(>z) 194s linear <= 0 0.3391 0.3218 1.054 0.146 194s (Adjusted p values reported -- single-step method) 194s 194s Multiple Contrast Test 194s 194s Contrasts: 194s linear 194s 0 -0.721 194s 79.1 -0.129 194s 117 0.005 194s 208 0.191 194s 398 0.654 194s 194s Contrast Correlation: 194s linear 194s linear 1 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s linear 1.054 0.146 194s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 194s Dose Response Model 194s 194s Model: sigEmax 194s Fit-type: general 194s 194s Coefficients dose-response model 194s eMax ed50 h 194s 0.4714 0.4880 0.5000 194s 194s Fitted to: 194s 1 2 3 4 194s 0.2846 0.2965 0.3502 0.3480 194s 194s Generalized residual sum of squares: 0.07825 194s Multiple Contrast Test 194s 194s Contrasts: 194s emax linear logistic linInt 194s 1 0.462 -0.429 0.511 -0.672 194s 2 0.505 0.002 0.507 0.437 194s 3 0.504 0.400 0.485 0.418 194s 4 0.527 0.810 0.497 0.428 194s 194s Contrast Correlation: 194s emax linear logistic linInt 194s emax 1.000 0.715 1.000 0.617 194s linear 0.715 1.000 0.698 0.863 194s logistic 1.000 0.698 1.000 0.598 194s linInt 0.617 0.863 0.598 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s emax 3.178 0.00193 194s logistic 3.164 0.00194 194s linear 2.640 0.00968 194s linInt 2.247 0.02721 194s Dose Response Model 194s 194s Model: sigEmax 194s Fit-type: generalMessage: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 194s 194s 194s Coefficients dose-response model 194s eMax ed50 h 194s 0.4714 0.4880 0.5000 194s 194s Fitted to: 194s 3 4 1 2 194s 0.3502 0.3480 0.2846 0.2965 194s 194s Generalized residual sum of squares: 0.07825 194s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 194s Multiple Contrast Test 194s 194s Contrasts: 194s emax linear logistic linInt 194s 1 0.462 -0.429 0.511 -0.672 194s 2 0.505 0.002 0.507 0.437 194s 3 0.504 0.400 0.485 0.418 194s 4 0.527 0.810 0.497 0.428 194s 194s Contrast Correlation: 194s emax linear logistic linInt 194s emax 1.000 0.715 1.000 0.617 194s linear 0.715 1.000 0.698 0.863 194s logistic 1.000 0.698 1.000 0.598 194s linInt 0.617 0.863 0.598 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s emax 3.178 0.00213 194s logistic 3.164 0.00174 194s linear 2.640 0.00941 194s linInt 2.247 0.02663 194s Dose Response Model 194s 194s Model: sigEmax 194s Fit-type: general 194s 194s Coefficients dose-response model 194s e0 eMax ed50 h 194s 0.2171 0.4714 0.4860 0.5000 194s 194s Fitted to: 194s 0 1 2 3 4 194s 0.2169 0.5016 0.5138 0.5677 0.5648 194s 194s Generalized residual sum of squares: 0.07892 194s Multiple Contrast Test 194s 194s Contrasts: 194s emax linear logistic linInt 194s 0 -0.894 -0.617 -0.894 -0.522 194s 1 0.207 -0.338 0.228 -0.573 194s 2 0.226 0.002 0.227 0.373 194s 3 0.227 0.315 0.218 0.358 194s 4 0.235 0.637 0.221 0.363 194s 194s Contrast Correlation: 194s emax linear logistic linInt 194s emax 1.000 0.715 1.000 0.618 194s linear 0.715 1.000 0.698 0.863 194s logistic 1.000 0.698 1.000 0.599 194s linInt 0.618 0.863 0.599 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s emax 3.186 0.00184 194s logistic 3.172 0.00177 194s linear 2.645 0.00956 194s linInt 2.254 0.02649 194s Message: Need bounds in "bnds" for nonlinear models, using default bounds from "defBnds". 194s Dose Response Model 194s 194s Model: sigEmax 194s Fit-type: general 194s 194s Coefficients dose-response model 194s e0 eMax ed50 h 194s 0.2171 0.4714 0.4860 0.5000 194s 194s Fitted to: 194s 2 3 0 1 4 194s 0.5138 0.5677 0.2169 0.5016 0.5648 194s 194s Generalized residual sum of squares: 0.07892 194s Multiple Contrast Test 194s 194s Contrasts: 194s emax linear logistic linInt 194s 0 -0.894 -0.617 -0.894 -0.522 194s 1 0.207 -0.338 0.228 -0.573 194s 2 0.226 0.002 0.227 0.373 194s 3 0.227 0.315 0.218 0.358 194s 4 0.235 0.637 0.221 0.363 194s 194s Contrast Correlation: 194s emax linear logistic linInt 194s emax 1.000 0.715 1.000 0.618 194s linear 0.715 1.000 0.698 0.863 194s logistic 1.000 0.698 1.000 0.599 194s linInt 0.618 0.863 0.599 1.000 194s 194s Multiple Contrast Test: 194s t-Stat adj-p 194s emax 3.186 0.00163 194s logistic 3.172 0.00192 194s linear 2.645 0.00981 194s linInt 2.254 0.02699 194s [1] TRUE 194s Warning messages: 194s 1: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 194s Warning from mvtnorm::pmvt: Covariance matrix not positive semidefinite. 194s 2: In MCTpval(contMat, corMat, df, tStat, alternative, mvtcontrol) : 194s Setting calculated p-value to NA 194s testsMCT.R passed 194s Loading required package: DoseFinding 195s Loading required package: quadprog 195s Loading required package: Rsolnp 195s testsoptContr.R passed 195s testsplotDRMod.R consists only from comments and returns non-zero exit value ... ignored 195s testssampSize.R passed 195s Loading required package: DoseFinding 196s [1] 0.3076509 196s [1] 0.6153019 196s [1] 0.9229528 196s [1] 2.673503 196s [1] 0.7028559 196s [1] 2.064397 196s [1] NA 197s testssamplMod.R passed 198s /usr/bin/xdg-open: 1032: www-browser: not found 198s /usr/bin/xdg-open: 1032: links2: not found 198s /usr/bin/xdg-open: 1032: elinks: not found 198s /usr/bin/xdg-open: 1032: links: not found 198s /usr/bin/xdg-open: 1032: lynx: not found 198s /usr/bin/xdg-open: 1032: w3m: not found 198s xdg-open: no method available for opening 'https://huisophiesunrshiny.shinyapps.io/designmcpmod/' 198s [ FAIL 0 | WARN 0 | SKIP 0 | PASS 53 ] 198s testthat.R passed 199s autopkgtest [22:09:25]: test run-unit-test: -----------------------] 199s run-unit-test PASS 199s autopkgtest [22:09:25]: test run-unit-test: - - - - - - - - - - results - - - - - - - - - - 199s autopkgtest [22:09:25]: test pkg-r-autopkgtest: preparing testbed 199s Reading package lists... 199s Building dependency tree... 199s Reading state information... 200s Starting pkgProblemResolver with broken count: 0 200s Starting 2 pkgProblemResolver with broken count: 0 200s Done 200s The following NEW packages will be installed: 200s build-essential cpp cpp-14 cpp-14-x86-64-linux-gnu cpp-x86-64-linux-gnu 200s dctrl-tools g++ g++-14 g++-14-x86-64-linux-gnu g++-x86-64-linux-gnu gcc 200s gcc-14 gcc-14-x86-64-linux-gnu gcc-x86-64-linux-gnu gfortran gfortran-14 200s gfortran-14-x86-64-linux-gnu gfortran-x86-64-linux-gnu icu-devtools libasan8 200s libblas-dev libbz2-dev libcc1-0 libdeflate-dev libgcc-14-dev 200s libgfortran-14-dev libhwasan0 libicu-dev libisl23 libitm1 libjpeg-dev 200s libjpeg-turbo8-dev libjpeg8-dev liblapack-dev liblsan0 liblzma-dev libmpc3 200s libncurses-dev libpcre2-16-0 libpcre2-32-0 libpcre2-dev libpcre2-posix3 200s libpkgconf3 libpng-dev libquadmath0 libreadline-dev libstdc++-14-dev 200s libtirpc-dev libtsan2 libubsan1 pkg-r-autopkgtest pkgconf pkgconf-bin 200s r-base-dev zlib1g-dev 200s 0 upgraded, 55 newly installed, 0 to remove and 0 not upgraded. 200s Need to get 103 MB of archives. 200s After this operation, 363 MB of additional disk space will be used. 200s Get:1 http://ftpmaster.internal/ubuntu plucky/main amd64 libisl23 amd64 0.27-1 [685 kB] 200s Get:2 http://ftpmaster.internal/ubuntu plucky/main amd64 libmpc3 amd64 1.3.1-1build2 [55.3 kB] 200s Get:3 http://ftpmaster.internal/ubuntu plucky/main amd64 cpp-14-x86-64-linux-gnu amd64 14.2.0-17ubuntu3 [11.9 MB] 201s Get:4 http://ftpmaster.internal/ubuntu plucky/main amd64 cpp-14 amd64 14.2.0-17ubuntu3 [1030 B] 201s Get:5 http://ftpmaster.internal/ubuntu plucky/main amd64 cpp-x86-64-linux-gnu amd64 4:14.2.0-1ubuntu1 [5586 B] 201s Get:6 http://ftpmaster.internal/ubuntu plucky/main amd64 cpp amd64 4:14.2.0-1ubuntu1 [22.4 kB] 201s Get:7 http://ftpmaster.internal/ubuntu plucky/main amd64 libcc1-0 amd64 15-20250222-0ubuntu1 [47.0 kB] 201s Get:8 http://ftpmaster.internal/ubuntu plucky/main amd64 libitm1 amd64 15-20250222-0ubuntu1 [28.6 kB] 201s Get:9 http://ftpmaster.internal/ubuntu plucky/main amd64 libasan8 amd64 15-20250222-0ubuntu1 [3055 kB] 201s Get:10 http://ftpmaster.internal/ubuntu plucky/main amd64 liblsan0 amd64 15-20250222-0ubuntu1 [1355 kB] 201s Get:11 http://ftpmaster.internal/ubuntu plucky/main amd64 libtsan2 amd64 15-20250222-0ubuntu1 [2756 kB] 201s Get:12 http://ftpmaster.internal/ubuntu plucky/main amd64 libubsan1 amd64 15-20250222-0ubuntu1 [1205 kB] 201s Get:13 http://ftpmaster.internal/ubuntu plucky/main amd64 libhwasan0 amd64 15-20250222-0ubuntu1 [1677 kB] 201s Get:14 http://ftpmaster.internal/ubuntu plucky/main amd64 libquadmath0 amd64 15-20250222-0ubuntu1 [152 kB] 201s Get:15 http://ftpmaster.internal/ubuntu plucky/main amd64 libgcc-14-dev amd64 14.2.0-17ubuntu3 [2816 kB] 201s Get:16 http://ftpmaster.internal/ubuntu plucky/main amd64 gcc-14-x86-64-linux-gnu amd64 14.2.0-17ubuntu3 [23.3 MB] 201s Get:17 http://ftpmaster.internal/ubuntu plucky/main amd64 gcc-14 amd64 14.2.0-17ubuntu3 [536 kB] 201s Get:18 http://ftpmaster.internal/ubuntu plucky/main amd64 gcc-x86-64-linux-gnu amd64 4:14.2.0-1ubuntu1 [1208 B] 201s Get:19 http://ftpmaster.internal/ubuntu plucky/main amd64 gcc amd64 4:14.2.0-1ubuntu1 [5004 B] 201s Get:20 http://ftpmaster.internal/ubuntu plucky/main amd64 libstdc++-14-dev amd64 14.2.0-17ubuntu3 [2486 kB] 201s Get:21 http://ftpmaster.internal/ubuntu plucky/main amd64 g++-14-x86-64-linux-gnu amd64 14.2.0-17ubuntu3 [13.4 MB] 201s Get:22 http://ftpmaster.internal/ubuntu plucky/main amd64 g++-14 amd64 14.2.0-17ubuntu3 [21.8 kB] 201s Get:23 http://ftpmaster.internal/ubuntu plucky/main amd64 g++-x86-64-linux-gnu amd64 4:14.2.0-1ubuntu1 [968 B] 201s Get:24 http://ftpmaster.internal/ubuntu plucky/main amd64 g++ amd64 4:14.2.0-1ubuntu1 [1100 B] 201s Get:25 http://ftpmaster.internal/ubuntu plucky/main amd64 build-essential amd64 12.10ubuntu1 [4928 B] 201s Get:26 http://ftpmaster.internal/ubuntu plucky/main amd64 dctrl-tools amd64 2.24-3build3 [106 kB] 201s Get:27 http://ftpmaster.internal/ubuntu plucky/main amd64 libgfortran-14-dev amd64 14.2.0-17ubuntu3 [966 kB] 201s Get:28 http://ftpmaster.internal/ubuntu plucky/main amd64 gfortran-14-x86-64-linux-gnu amd64 14.2.0-17ubuntu3 [12.6 MB] 201s Get:29 http://ftpmaster.internal/ubuntu plucky/main amd64 gfortran-14 amd64 14.2.0-17ubuntu3 [13.6 kB] 201s Get:30 http://ftpmaster.internal/ubuntu plucky/main amd64 gfortran-x86-64-linux-gnu amd64 4:14.2.0-1ubuntu1 [1022 B] 201s Get:31 http://ftpmaster.internal/ubuntu plucky/main amd64 gfortran amd64 4:14.2.0-1ubuntu1 [1174 B] 201s Get:32 http://ftpmaster.internal/ubuntu plucky/main amd64 icu-devtools amd64 76.1-1ubuntu2 [237 kB] 201s Get:33 http://ftpmaster.internal/ubuntu plucky/main amd64 libblas-dev amd64 3.12.1-2 [338 kB] 201s Get:34 http://ftpmaster.internal/ubuntu plucky/main amd64 libbz2-dev amd64 1.0.8-6 [33.8 kB] 201s Get:35 http://ftpmaster.internal/ubuntu plucky/main amd64 libdeflate-dev amd64 1.23-1 [71.7 kB] 201s Get:36 http://ftpmaster.internal/ubuntu plucky/main amd64 libicu-dev amd64 76.1-1ubuntu2 [12.6 MB] 201s Get:37 http://ftpmaster.internal/ubuntu plucky/main amd64 libjpeg-turbo8-dev amd64 2.1.5-3ubuntu2 [324 kB] 201s Get:38 http://ftpmaster.internal/ubuntu plucky/main amd64 libjpeg8-dev amd64 8c-2ubuntu11 [1484 B] 201s Get:39 http://ftpmaster.internal/ubuntu plucky/main amd64 libjpeg-dev amd64 8c-2ubuntu11 [1482 B] 201s Get:40 http://ftpmaster.internal/ubuntu plucky/main amd64 liblapack-dev amd64 3.12.1-2 [6489 kB] 201s Get:41 http://ftpmaster.internal/ubuntu plucky/main amd64 libncurses-dev amd64 6.5+20250216-2 [424 kB] 201s Get:42 http://ftpmaster.internal/ubuntu plucky/main amd64 libpcre2-16-0 amd64 10.45-1 [268 kB] 201s Get:43 http://ftpmaster.internal/ubuntu plucky/main amd64 libpcre2-32-0 amd64 10.45-1 [251 kB] 201s Get:44 http://ftpmaster.internal/ubuntu plucky/main amd64 libpcre2-posix3 amd64 10.45-1 [7204 B] 201s Get:45 http://ftpmaster.internal/ubuntu plucky/main amd64 libpcre2-dev amd64 10.45-1 [908 kB] 201s Get:46 http://ftpmaster.internal/ubuntu plucky/main amd64 libpkgconf3 amd64 1.8.1-4 [32.3 kB] 201s Get:47 http://ftpmaster.internal/ubuntu plucky/main amd64 zlib1g-dev amd64 1:1.3.dfsg+really1.3.1-1ubuntu1 [895 kB] 201s Get:48 http://ftpmaster.internal/ubuntu plucky/main amd64 libpng-dev amd64 1.6.47-1 [298 kB] 201s Get:49 http://ftpmaster.internal/ubuntu plucky/main amd64 libreadline-dev amd64 8.2-6 [184 kB] 201s Get:50 http://ftpmaster.internal/ubuntu plucky/main amd64 liblzma-dev amd64 5.6.4-1 [189 kB] 201s Get:51 http://ftpmaster.internal/ubuntu plucky/main amd64 pkgconf-bin amd64 1.8.1-4 [21.6 kB] 201s Get:52 http://ftpmaster.internal/ubuntu plucky/main amd64 pkgconf amd64 1.8.1-4 [16.8 kB] 201s Get:53 http://ftpmaster.internal/ubuntu plucky/main amd64 libtirpc-dev amd64 1.3.4+ds-1.3 [193 kB] 201s Get:54 http://ftpmaster.internal/ubuntu plucky/universe amd64 r-base-dev all 4.4.3-1 [4176 B] 201s Get:55 http://ftpmaster.internal/ubuntu plucky/universe amd64 pkg-r-autopkgtest all 20231212ubuntu1 [6448 B] 202s Fetched 103 MB in 1s (117 MB/s) 202s Selecting previously unselected package libisl23:amd64. 202s (Reading database ... (Reading database ... 5% (Reading database ... 10% (Reading database ... 15% (Reading database ... 20% (Reading database ... 25% (Reading database ... 30% (Reading database ... 35% (Reading database ... 40% (Reading database ... 45% (Reading database ... 50% (Reading database ... 55% (Reading database ... 60% (Reading database ... 65% (Reading database ... 70% (Reading database ... 75% (Reading database ... 80% (Reading database ... 85% (Reading database ... 90% (Reading database ... 95% (Reading database ... 100% (Reading database ... 94682 files and directories currently installed.) 202s Preparing to unpack .../00-libisl23_0.27-1_amd64.deb ... 202s Unpacking libisl23:amd64 (0.27-1) ... 202s Selecting previously unselected package libmpc3:amd64. 202s Preparing to unpack .../01-libmpc3_1.3.1-1build2_amd64.deb ... 202s Unpacking libmpc3:amd64 (1.3.1-1build2) ... 202s Selecting previously unselected package cpp-14-x86-64-linux-gnu. 202s Preparing to unpack .../02-cpp-14-x86-64-linux-gnu_14.2.0-17ubuntu3_amd64.deb ... 202s Unpacking cpp-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 202s Selecting previously unselected package cpp-14. 202s Preparing to unpack .../03-cpp-14_14.2.0-17ubuntu3_amd64.deb ... 202s Unpacking cpp-14 (14.2.0-17ubuntu3) ... 202s Selecting previously unselected package cpp-x86-64-linux-gnu. 202s Preparing to unpack .../04-cpp-x86-64-linux-gnu_4%3a14.2.0-1ubuntu1_amd64.deb ... 202s Unpacking cpp-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 202s Selecting previously unselected package cpp. 202s Preparing to unpack .../05-cpp_4%3a14.2.0-1ubuntu1_amd64.deb ... 202s Unpacking cpp (4:14.2.0-1ubuntu1) ... 202s Selecting previously unselected package libcc1-0:amd64. 202s Preparing to unpack .../06-libcc1-0_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libcc1-0:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package libitm1:amd64. 202s Preparing to unpack .../07-libitm1_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libitm1:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package libasan8:amd64. 202s Preparing to unpack .../08-libasan8_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libasan8:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package liblsan0:amd64. 202s Preparing to unpack .../09-liblsan0_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking liblsan0:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package libtsan2:amd64. 202s Preparing to unpack .../10-libtsan2_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libtsan2:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package libubsan1:amd64. 202s Preparing to unpack .../11-libubsan1_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libubsan1:amd64 (15-20250222-0ubuntu1) ... 202s Selecting previously unselected package libhwasan0:amd64. 202s Preparing to unpack .../12-libhwasan0_15-20250222-0ubuntu1_amd64.deb ... 202s Unpacking libhwasan0:amd64 (15-20250222-0ubuntu1) ... 203s Selecting previously unselected package libquadmath0:amd64. 203s Preparing to unpack .../13-libquadmath0_15-20250222-0ubuntu1_amd64.deb ... 203s Unpacking libquadmath0:amd64 (15-20250222-0ubuntu1) ... 203s Selecting previously unselected package libgcc-14-dev:amd64. 203s Preparing to unpack .../14-libgcc-14-dev_14.2.0-17ubuntu3_amd64.deb ... 203s Unpacking libgcc-14-dev:amd64 (14.2.0-17ubuntu3) ... 203s Selecting previously unselected package gcc-14-x86-64-linux-gnu. 203s Preparing to unpack .../15-gcc-14-x86-64-linux-gnu_14.2.0-17ubuntu3_amd64.deb ... 203s Unpacking gcc-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 203s Selecting previously unselected package gcc-14. 203s Preparing to unpack .../16-gcc-14_14.2.0-17ubuntu3_amd64.deb ... 203s Unpacking gcc-14 (14.2.0-17ubuntu3) ... 203s Selecting previously unselected package gcc-x86-64-linux-gnu. 203s Preparing to unpack .../17-gcc-x86-64-linux-gnu_4%3a14.2.0-1ubuntu1_amd64.deb ... 203s Unpacking gcc-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 203s Selecting previously unselected package gcc. 203s Preparing to unpack .../18-gcc_4%3a14.2.0-1ubuntu1_amd64.deb ... 203s Unpacking gcc (4:14.2.0-1ubuntu1) ... 203s Selecting previously unselected package libstdc++-14-dev:amd64. 203s Preparing to unpack .../19-libstdc++-14-dev_14.2.0-17ubuntu3_amd64.deb ... 203s Unpacking libstdc++-14-dev:amd64 (14.2.0-17ubuntu3) ... 203s Selecting previously unselected package g++-14-x86-64-linux-gnu. 203s Preparing to unpack .../20-g++-14-x86-64-linux-gnu_14.2.0-17ubuntu3_amd64.deb ... 203s Unpacking g++-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 204s Selecting previously unselected package g++-14. 204s Preparing to unpack .../21-g++-14_14.2.0-17ubuntu3_amd64.deb ... 204s Unpacking g++-14 (14.2.0-17ubuntu3) ... 204s Selecting previously unselected package g++-x86-64-linux-gnu. 204s Preparing to unpack .../22-g++-x86-64-linux-gnu_4%3a14.2.0-1ubuntu1_amd64.deb ... 204s Unpacking g++-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 204s Selecting previously unselected package g++. 204s Preparing to unpack .../23-g++_4%3a14.2.0-1ubuntu1_amd64.deb ... 204s Unpacking g++ (4:14.2.0-1ubuntu1) ... 204s Selecting previously unselected package build-essential. 204s Preparing to unpack .../24-build-essential_12.10ubuntu1_amd64.deb ... 204s Unpacking build-essential (12.10ubuntu1) ... 204s Selecting previously unselected package dctrl-tools. 204s Preparing to unpack .../25-dctrl-tools_2.24-3build3_amd64.deb ... 204s Unpacking dctrl-tools (2.24-3build3) ... 204s Selecting previously unselected package libgfortran-14-dev:amd64. 204s Preparing to unpack .../26-libgfortran-14-dev_14.2.0-17ubuntu3_amd64.deb ... 204s Unpacking libgfortran-14-dev:amd64 (14.2.0-17ubuntu3) ... 204s Selecting previously unselected package gfortran-14-x86-64-linux-gnu. 204s Preparing to unpack .../27-gfortran-14-x86-64-linux-gnu_14.2.0-17ubuntu3_amd64.deb ... 204s Unpacking gfortran-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 204s Selecting previously unselected package gfortran-14. 204s Preparing to unpack .../28-gfortran-14_14.2.0-17ubuntu3_amd64.deb ... 204s Unpacking gfortran-14 (14.2.0-17ubuntu3) ... 204s Selecting previously unselected package gfortran-x86-64-linux-gnu. 204s Preparing to unpack .../29-gfortran-x86-64-linux-gnu_4%3a14.2.0-1ubuntu1_amd64.deb ... 204s Unpacking gfortran-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 204s Selecting previously unselected package gfortran. 204s Preparing to unpack .../30-gfortran_4%3a14.2.0-1ubuntu1_amd64.deb ... 204s Unpacking gfortran (4:14.2.0-1ubuntu1) ... 204s Selecting previously unselected package icu-devtools. 204s Preparing to unpack .../31-icu-devtools_76.1-1ubuntu2_amd64.deb ... 204s Unpacking icu-devtools (76.1-1ubuntu2) ... 204s Selecting previously unselected package libblas-dev:amd64. 204s Preparing to unpack .../32-libblas-dev_3.12.1-2_amd64.deb ... 204s Unpacking libblas-dev:amd64 (3.12.1-2) ... 204s Selecting previously unselected package libbz2-dev:amd64. 204s Preparing to unpack .../33-libbz2-dev_1.0.8-6_amd64.deb ... 204s Unpacking libbz2-dev:amd64 (1.0.8-6) ... 204s Selecting previously unselected package libdeflate-dev:amd64. 204s Preparing to unpack .../34-libdeflate-dev_1.23-1_amd64.deb ... 204s Unpacking libdeflate-dev:amd64 (1.23-1) ... 204s Selecting previously unselected package libicu-dev:amd64. 204s Preparing to unpack .../35-libicu-dev_76.1-1ubuntu2_amd64.deb ... 204s Unpacking libicu-dev:amd64 (76.1-1ubuntu2) ... 205s Selecting previously unselected package libjpeg-turbo8-dev:amd64. 205s Preparing to unpack .../36-libjpeg-turbo8-dev_2.1.5-3ubuntu2_amd64.deb ... 205s Unpacking libjpeg-turbo8-dev:amd64 (2.1.5-3ubuntu2) ... 205s Selecting previously unselected package libjpeg8-dev:amd64. 205s Preparing to unpack .../37-libjpeg8-dev_8c-2ubuntu11_amd64.deb ... 205s Unpacking libjpeg8-dev:amd64 (8c-2ubuntu11) ... 205s Selecting previously unselected package libjpeg-dev:amd64. 205s Preparing to unpack .../38-libjpeg-dev_8c-2ubuntu11_amd64.deb ... 205s Unpacking libjpeg-dev:amd64 (8c-2ubuntu11) ... 205s Selecting previously unselected package liblapack-dev:amd64. 205s Preparing to unpack .../39-liblapack-dev_3.12.1-2_amd64.deb ... 205s Unpacking liblapack-dev:amd64 (3.12.1-2) ... 205s Selecting previously unselected package libncurses-dev:amd64. 205s Preparing to unpack .../40-libncurses-dev_6.5+20250216-2_amd64.deb ... 205s Unpacking libncurses-dev:amd64 (6.5+20250216-2) ... 205s Selecting previously unselected package libpcre2-16-0:amd64. 205s Preparing to unpack .../41-libpcre2-16-0_10.45-1_amd64.deb ... 205s Unpacking libpcre2-16-0:amd64 (10.45-1) ... 205s Selecting previously unselected package libpcre2-32-0:amd64. 205s Preparing to unpack .../42-libpcre2-32-0_10.45-1_amd64.deb ... 205s Unpacking libpcre2-32-0:amd64 (10.45-1) ... 205s Selecting previously unselected package libpcre2-posix3:amd64. 205s Preparing to unpack .../43-libpcre2-posix3_10.45-1_amd64.deb ... 205s Unpacking libpcre2-posix3:amd64 (10.45-1) ... 205s Selecting previously unselected package libpcre2-dev:amd64. 205s Preparing to unpack .../44-libpcre2-dev_10.45-1_amd64.deb ... 205s Unpacking libpcre2-dev:amd64 (10.45-1) ... 205s Selecting previously unselected package libpkgconf3:amd64. 205s Preparing to unpack .../45-libpkgconf3_1.8.1-4_amd64.deb ... 205s Unpacking libpkgconf3:amd64 (1.8.1-4) ... 205s Selecting previously unselected package zlib1g-dev:amd64. 205s Preparing to unpack .../46-zlib1g-dev_1%3a1.3.dfsg+really1.3.1-1ubuntu1_amd64.deb ... 205s Unpacking zlib1g-dev:amd64 (1:1.3.dfsg+really1.3.1-1ubuntu1) ... 205s Selecting previously unselected package libpng-dev:amd64. 205s Preparing to unpack .../47-libpng-dev_1.6.47-1_amd64.deb ... 205s Unpacking libpng-dev:amd64 (1.6.47-1) ... 205s Selecting previously unselected package libreadline-dev:amd64. 205s Preparing to unpack .../48-libreadline-dev_8.2-6_amd64.deb ... 205s Unpacking libreadline-dev:amd64 (8.2-6) ... 205s Selecting previously unselected package liblzma-dev:amd64. 205s Preparing to unpack .../49-liblzma-dev_5.6.4-1_amd64.deb ... 205s Unpacking liblzma-dev:amd64 (5.6.4-1) ... 205s Selecting previously unselected package pkgconf-bin. 205s Preparing to unpack .../50-pkgconf-bin_1.8.1-4_amd64.deb ... 205s Unpacking pkgconf-bin (1.8.1-4) ... 205s Selecting previously unselected package pkgconf:amd64. 205s Preparing to unpack .../51-pkgconf_1.8.1-4_amd64.deb ... 205s Unpacking pkgconf:amd64 (1.8.1-4) ... 205s Selecting previously unselected package libtirpc-dev:amd64. 205s Preparing to unpack .../52-libtirpc-dev_1.3.4+ds-1.3_amd64.deb ... 205s Unpacking libtirpc-dev:amd64 (1.3.4+ds-1.3) ... 205s Selecting previously unselected package r-base-dev. 205s Preparing to unpack .../53-r-base-dev_4.4.3-1_all.deb ... 205s Unpacking r-base-dev (4.4.3-1) ... 205s Selecting previously unselected package pkg-r-autopkgtest. 206s Preparing to unpack .../54-pkg-r-autopkgtest_20231212ubuntu1_all.deb ... 206s Unpacking pkg-r-autopkgtest (20231212ubuntu1) ... 206s Setting up libjpeg-turbo8-dev:amd64 (2.1.5-3ubuntu2) ... 206s Setting up libncurses-dev:amd64 (6.5+20250216-2) ... 206s Setting up libreadline-dev:amd64 (8.2-6) ... 206s Setting up libpcre2-16-0:amd64 (10.45-1) ... 206s Setting up libpcre2-32-0:amd64 (10.45-1) ... 206s Setting up libtirpc-dev:amd64 (1.3.4+ds-1.3) ... 206s Setting up libpkgconf3:amd64 (1.8.1-4) ... 206s Setting up libquadmath0:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libmpc3:amd64 (1.3.1-1build2) ... 206s Setting up icu-devtools (76.1-1ubuntu2) ... 206s Setting up pkgconf-bin (1.8.1-4) ... 206s Setting up liblzma-dev:amd64 (5.6.4-1) ... 206s Setting up libubsan1:amd64 (15-20250222-0ubuntu1) ... 206s Setting up zlib1g-dev:amd64 (1:1.3.dfsg+really1.3.1-1ubuntu1) ... 206s Setting up libpcre2-posix3:amd64 (10.45-1) ... 206s Setting up libhwasan0:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libasan8:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libtsan2:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libjpeg8-dev:amd64 (8c-2ubuntu11) ... 206s Setting up libisl23:amd64 (0.27-1) ... 206s Setting up libdeflate-dev:amd64 (1.23-1) ... 206s Setting up libicu-dev:amd64 (76.1-1ubuntu2) ... 206s Setting up libcc1-0:amd64 (15-20250222-0ubuntu1) ... 206s Setting up liblsan0:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libblas-dev:amd64 (3.12.1-2) ... 206s update-alternatives: using /usr/lib/x86_64-linux-gnu/blas/libblas.so to provide /usr/lib/x86_64-linux-gnu/libblas.so (libblas.so-x86_64-linux-gnu) in auto mode 206s Setting up dctrl-tools (2.24-3build3) ... 206s Setting up libitm1:amd64 (15-20250222-0ubuntu1) ... 206s Setting up libbz2-dev:amd64 (1.0.8-6) ... 206s Setting up libpcre2-dev:amd64 (10.45-1) ... 206s Setting up libpng-dev:amd64 (1.6.47-1) ... 206s Setting up libjpeg-dev:amd64 (8c-2ubuntu11) ... 206s Setting up pkgconf:amd64 (1.8.1-4) ... 206s Setting up liblapack-dev:amd64 (3.12.1-2) ... 206s update-alternatives: using /usr/lib/x86_64-linux-gnu/lapack/liblapack.so to provide /usr/lib/x86_64-linux-gnu/liblapack.so (liblapack.so-x86_64-linux-gnu) in auto mode 206s Setting up cpp-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 206s Setting up cpp-14 (14.2.0-17ubuntu3) ... 206s Setting up libgcc-14-dev:amd64 (14.2.0-17ubuntu3) ... 206s Setting up libstdc++-14-dev:amd64 (14.2.0-17ubuntu3) ... 206s Setting up cpp-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 206s Setting up libgfortran-14-dev:amd64 (14.2.0-17ubuntu3) ... 206s Setting up cpp (4:14.2.0-1ubuntu1) ... 206s Setting up gcc-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 206s Setting up gcc-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 206s Setting up gcc-14 (14.2.0-17ubuntu3) ... 206s Setting up gfortran-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 206s Setting up g++-14-x86-64-linux-gnu (14.2.0-17ubuntu3) ... 206s Setting up g++-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 206s Setting up g++-14 (14.2.0-17ubuntu3) ... 206s Setting up gfortran-14 (14.2.0-17ubuntu3) ... 206s Setting up gfortran-x86-64-linux-gnu (4:14.2.0-1ubuntu1) ... 206s Setting up gcc (4:14.2.0-1ubuntu1) ... 206s Setting up g++ (4:14.2.0-1ubuntu1) ... 206s update-alternatives: using /usr/bin/g++ to provide /usr/bin/c++ (c++) in auto mode 206s Setting up build-essential (12.10ubuntu1) ... 206s Setting up gfortran (4:14.2.0-1ubuntu1) ... 206s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f95 (f95) in auto mode 206s update-alternatives: warning: skip creation of /usr/share/man/man1/f95.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f95) doesn't exist 206s update-alternatives: using /usr/bin/gfortran to provide /usr/bin/f77 (f77) in auto mode 206s update-alternatives: warning: skip creation of /usr/share/man/man1/f77.1.gz because associated file /usr/share/man/man1/gfortran.1.gz (of link group f77) doesn't exist 206s Setting up r-base-dev (4.4.3-1) ... 206s Setting up pkg-r-autopkgtest (20231212ubuntu1) ... 206s Processing triggers for libc-bin (2.41-1ubuntu2) ... 206s Processing triggers for man-db (2.13.0-1) ... 207s Processing triggers for install-info (7.1.1-1) ... 207s autopkgtest [22:09:33]: test pkg-r-autopkgtest: /usr/share/dh-r/pkg-r-autopkgtest 207s autopkgtest [22:09:33]: test pkg-r-autopkgtest: [----------------------- 207s Test: Try to load the R library DoseFinding 208s 208s R version 4.4.3 (2025-02-28) -- "Trophy Case" 208s Copyright (C) 2025 The R Foundation for Statistical Computing 208s Platform: x86_64-pc-linux-gnu 208s 208s R is free software and comes with ABSOLUTELY NO WARRANTY. 208s You are welcome to redistribute it under certain conditions. 208s Type 'license()' or 'licence()' for distribution details. 208s 208s R is a collaborative project with many contributors. 208s Type 'contributors()' for more information and 208s 'citation()' on how to cite R or R packages in publications. 208s 208s Type 'demo()' for some demos, 'help()' for on-line help, or 208s 'help.start()' for an HTML browser interface to help. 208s Type 'q()' to quit R. 208s 208s > library('DoseFinding') 208s > 208s > 208s Other tests are currently unsupported! 208s They will be progressively added. 209s autopkgtest [22:09:35]: test pkg-r-autopkgtest: -----------------------] 209s pkg-r-autopkgtest PASS 209s autopkgtest [22:09:35]: test pkg-r-autopkgtest: - - - - - - - - - - results - - - - - - - - - - 209s autopkgtest [22:09:35]: @@@@@@@@@@@@@@@@@@@@ summary 209s run-unit-test PASS 209s pkg-r-autopkgtest PASS 227s nova [W] Skipping flock for amd64 227s Creating nova instance adt-plucky-amd64-r-cran-dosefinding-20250315-220606-juju-7f2275-prod-proposed-migration-environment-2-3e42c4f3-bee0-4546-a5c4-d13129a7d601 from image adt/ubuntu-plucky-amd64-server-20250306.img (UUID 60d877d7-b74c-4f24-920d-f4570db0a338)... 227s nova [W] Timed out waiting for be35c9e7-d172-4807-95b9-a6009112767b to get deleted.